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Du Lei L Department of Pediatric Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, No.1665, Kongjiang Road, Shanghai, 200092, - - 2014
The survival rate of infants with gastroschisis has improved significantly. It is over 90% in developed countries, but 50% in developing countries. This study aimed to investigate the factors improving the survival rate of infants with gastroschisis in developing countries. Neonates meeting the inclusion criteria, who presented to our center ...
Aliaga Sofia S Division of Neonatal-Perinatal Medicine, University of North Carolina, Chapel Hill, North - - 2014
Neonatal invasive candidiasis is associated with significant morbidity and mortality. We describe the association between invasive candidiasis and changes in use of antifungal prophylaxis, empirical antifungal therapy, and broad-spectrum antibacterial antibiotics over time. We examined data from 709 325 infants at 322 NICUs managed by the Pediatrix Medical Group from 1997 ...
Knirsch Walter W Division of Pediatric Cardiology, University Children's Hospital, Steinwiesstrasse 75, 8032, Zurich, Switzerland, - - 2014
Infants with hypoplastic left heart syndrome (HLHS) are at risk for interstage morbidity and mortality, especially between the first and second surgical stages after the Norwood and hybrid procedures. This study compared the morbidity and mortality of patients treated by either the Norwood or the hybrid procedure for HLHS between ...
Meyer-Marcotty Philipp P Department of Orthodontics (Head: Prof. Dr. A. Stellzig-Eisenhauer), Dental Clinic of the Medical Faculty, University of Wuerzburg, Germany. Electronic address: - - 2014
This study analyses pathomorphological and physiological head shapes and classifies the pathomorphology in positional plagiocephaly and brachycephaly. 78 infants with a positional plagiocephaly (5.99 months) and 32 infants with a positional brachycephaly (6.53 months) with a Cephalic index > 94% were investigated in this study and compared to a matched control group ...
Lim Kathleen K Department of Pediatrics, Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, - - 2014
The precision of oxygen saturation (SpO2) targeting in preterm infants on continuous positive airway pressure (CPAP) is incompletely characterized. We therefore evaluated SpO2 targeting in infants solely receiving CPAP, aiming to describe their SpO2 profile, to document the frequency of prolonged hyperoxia and hypoxia episodes and of fraction of inspired ...
Kadlub Natacha N APHP (Head: Prof. Vazquez), Hôpital Necker Enfants Malades, Service de chirurgie Maxillofaciale, Paris 75015, France; Université Paris V, UFR de Médecine Paris Descartes, Paris 75006, France; Centre de références des malformations de la face et de la cavité buccale (Head: Prof. Vazquez), Paris 75015, France; Laboratoire de Physiopathologie orale et Moléculaire (Head: Prof. Berdal), INSERM, UMRS 872, Equipe 5, Centre de recherche des Cordeliers, Paris 75006, France. Electronic address: - - 2014
In children, and specifically in infants, odontogenic myxomas are extremely rare. In infants, myxoma seems to display mostly the same clinical, radiological and pathological characteristics. This paper presents a series of odontogenic myxomas in infant patients. Four infant patients were included in this retrospective study. The clinical, radiological and pathological ...
Vemulakonda Vijaya M VM Department of Pediatric Urology, Children's Hospital Colorado, Division of Urology, Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado. Electronic address: - - 2014
To identify geographic variability in the imaging of infants with congenital hydronephrosis at initial pediatric urologic evaluation. We performed a retrospective review of infants aged ≤12 months with congenital hydronephrosis seen as new patients from October 2010 to September 2011 at 3 regionally diverse pediatric urology practices: University of Virginia Hospital, ...
Ramzan Mohammed M 1Pediatric Hematology Oncology & Bone Marrow Transplant Unit, Department of Pediatrics, Institute of Child Health, Sir Ganga Ram Hospital , Old Rajinder Nagar, New Delhi , - - 2014
There is paucity of outcome data for hemophagocytic lymphohistiocytosis (HLH) in infants from India, especially post stem cell transplant (SCT). We report outcome data of eight infants diagnosed with HLH. Mean age was 7.1 months (range 2-11). Mutation analysis was possible in seven patients. One patient had Griscelli syndrome. In ...
Alemzadeh-Ansari Mohammad Hasan - - 2014
Introduction. Urinary calculi in infants are relatively infrequent, but their incidence has increased in the recent decades. The aim of this study was to investigate the clinical presentation, metabolic risk factors, and urinary tract abnormalities in infants suffering from kidney calculus. Materials and Methods. A total of 152 infants were ...
Liu Bo B Department of Radiology, Children's Hospital of Chongqing Medical University, Chongqing, - - 2014
Magnetic resonance cholangiopancreatography (MRCP) is widely accepted for visualization of the biliary system. However, the sensitivity and specificity of MRCP for the diagnosis of biliary atresia (BA) are still not fully elucidated. This study aimed to investigate the diagnostic value of three-dimensional MRCP (3D-MRCP) for BA in a large cohort ...
Shahjahan M M Dr Md Shahjahan, MS, Pediatric Surgery, Department of Pediatric Surgery, Dhaka Shishu (Children) Hospital, Dhaka, - - 2014
Hirschsprung's disease (HD) is developmental disorder of the enteric nervous system. Diagnosis can be confirmed by rectal biopsy. The surgical management of HD includes so many procedures. The purpose of this study was to evaluate the out come of single-stage transanal endorectal pull-through operation for short segment HD in neonates ...
Stathis George G Department of Radiology, School of Medicine, National and Kapodistrian University of Athens, General University Hospital "ATTIKON", Chaidari, GR 124 62, Athens, - - 2014
Acute lipoid pneumonia (LP) in children is a rare disorder caused by the aspiration of oil-based substances and is difficult to diagnose due to non-specific clinical symptoms and radiological findings. We report the case of a 5-month-old male infant with acute LP caused by accidental aspiration of a large amount ...
Bawa Pritish P 0000-0003-4130-7554 Department of Radiology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, - - 2014
Pulmonary interstitial emphysema (PIE) is not an uncommon finding in premature infants with respiratory distress who need respiratory support by mechanical ventilation. PIE has been reported in a few cases of neonates in whom either no treatment other than room air was given or they were given continuous positive end-expiratory ...
Albanna Ehab Am EA Department of Pediatrics, Faulty of Medicine Zagazig University, - - 2014
Calprotectin is a 36 kDa protein present in the cytoplasm of the neutrophil has antimicrobial and apoptosis inducing activities. In vitro studies have shown that calprotectin inhibits the growth of various microorganisms. Necrotizing enterocolitis (NEC) remains one of the leading causes of morbidity and mortality in neonatal intensive care units ...
Jani P P Grace Centre's for Newborn Care, The Children's Hospital at Westmead, University of Sydney, Westmead, NSW, - - 2014
To provide analysis on infants treated for right-sided congenital diaphragmatic hernia (RCDH) including mortality, neonatal morbidities, and associated congenital anomalies. We reviewed records of infants admitted with RCDH from 1985 to 2010. A total of 160 infants with CDH were identified; of them 22 infants had RCDH, 14 (64%) were ...
Laudanski Piotr P 0000-0001-8955-8198 Department of Perinatology and Obstetrics, Medical University of Bialystok, Bialystok, 15-276 Podlasie, Poland ; Department of Perinatology and Obstetrics, Medical University of Bialystok, Marii Sklodowskiej Curie 24a, 15-273 Bialystok, - - 2014
Introduction. Nowadays it is thought that the main cause of premature birth is subclinical infection. However, none of the currently used methods provide effective prevention to preterm labor. The aim of the study was to determine the concentration of selected chemokines in sera of patients with premature birth without clinical ...
Whitsett Jeffrey A JA Perinatal Institute, Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, and the University of Cincinnati College of Medicine, Cincinnati, Ohio, - - 2014
Advances in the physiology, biochemistry, molecular and cell biology of the pulmonary surfactant system transformed the clinical care and outcome of preterm infants with respiratory distress syndrome. The molecular era of surfactant biology provided genetic insights into the pathogenesis of pulmonary disorders, previously termed 'idiopathic', that affect newborn infants, children ...
El Mazloum Dania D Unit of Pediatric Respiratory Medicine and Allergy, Women's and Children's Health Department, University of Padova, Padova, - - 2014
Chronic respiratory morbidity is a common adverse outcome of preterm birth, especially in infants who develop bronchopulmonary dysplasia (BPD), which is still a major cause of long-term lung dysfunction with a heavy burden on health care services and medical resources throughout childhood. The most severely affected patients remain symptomatic even ...
Vento Máximo M Neonatal Research Unit, Division of Neonatology, University and Polytechnic Hospital La Fe, Valencia, - - 2014
Oxygen is one of the most widely used drugs in the neonatal period. A lack of knowledge of oxygen metabolism and toxicity has prompted guidelines to fluctuate from liberal use to treat respiratory distress to restriction to avoid retinopathy of prematurity. In recent years, studies performed in the immediate postnatal ...
Gallini F F Department of Pediatrics, Neonatal Unit Catholic University Largo F. Vito 1, 00136 Rome - Italy. - - 2014
Bronchopulmonary dysplasia (BPD) is a chronic lung disorder common among very preterm infants affecting significantly not only mortality and morbidity but also neurodevelopmental outcomes. This review aims to identify the short and long-term neurodevelopmental outcomes of infants with BPD, considering that the new definition of BPD allows to relate severity ...
Ventura M L ML . - - 2014
Despite a even more frequent use to non-invasive respiratory support, mechanical ventilation is stilloften necessary for supporting premature infants with lung disease. Protracted mechanical ventilation is associatedwith increased morbidity and mortality and thus the earliest weaning from invasive respiratory supportis desirable. Weaning protocols may be helpful in achieving more rapid ...
Wright Lydia K LK Emory University School of Medicine, Atlanta, Georgia; Seattle Children's Hospital, Seattle, - - 2013
Prenatal diagnosis of congenital heart defects (CHDs) is increasingly common, but it is still unclear whether it translates to improved postoperative outcomes. We performed a retrospective cohort study of all infants (aged <1 year) who underwent surgery for CHDs from 2006 to 2011 at a single institution. Primary outcomes were in-hospital ...
Seltzer Laurie E LE Department of Neurology, University of Rochester Medical Center, Rochester, New York. Electronic address: - - 2013
During the surgical repair of infants with congenital cardiac defects, there can be periods of decreased cerebral blood flow, particularly during deep hypothermic circulatory arrest. As a result, these infants are at increased risk for seizures and long-term neurodevelopmental difficulties. Thirty-two infants with congenital heart disease had continuous video-electroencephalographic (EEG) ...
Hernández-Bou Susanna S Paediatric Emergency Department, Hospital Sant Joan de Déu Barcelona, - - 2013
Some authors have assessed the utility of considering various risk factors in predicting bacteremia in young infants with urinary tract infection (UTI) in studies that included only febrile patients. Our aims were to determine whether fever was a predictor for bacteremia and to identify other associated risk factors. A retrospective ...
Anderson de Moreno Lauren C LC Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, Indianapolis, Indiana, - - 2013
To determine if patients who were born premature have a higher incidence of aspiration following supraglottoplasty compared to patients born full term. Retrospective study. Two thousand three hundred sixty (2360) patient charts from Riley Hospital for Children were reviewed retrospectively. Patients had already been treated for laryngomalacia with supraglottoplasty by ...
Greenberg S Bruce - - 2013
Airway abnormalities are frequently associated with congenital heart disease in infants and children. Respiratory distress in these children frequently requires prolonged respiratory support. Wide-detector dynamic pulmonary computed tomography angiography (DP-CTA) is a non-invasive technique that completely evaluates vascular and airway abnormalities during a single breathe. Our purpose was to evaluate ...
Valentine M C - - 2013
Infant leukemia (IL) is a rare sporadic cancer with a grim prognosis. While most cases are accompanied by MLL-rearrangements and harbor very few somatic mutations; less is known about the genetics of the cases without MLL translocations. We performed the largest exome sequencing study to date on matched non-cancer DNA ...
van Wijk Michiel - - 2013
To evaluate the mechanisms underlying gastroesophageal reflux (GER) following esophageal atresia (EA) repair and gastroesophageal function in infants and adults born with EA. Ten consecutive infants born with EA as well as 10 randomly selected adult EA patients were studied during their first postoperative follow-up visit and a purposely planned ...
Lally Kevin P - - 2013
Congenital diaphragmatic hernia (CDH) remains a significant cause of neonatal death. A wide spectrum of disease severity and treatment strategies makes comparisons challenging. The objective of this study was to create a standardized reporting system for CDH. Data were prospectively collected on all live born infants with CDH from 51 ...
Banani Seyed Abbas SA Shiraz University of Medical Sciences (SUMS), Department of Pediatric Surgery, Shiraz, - - 2013
Skin damage secondary to peristomal leakage is a fairly common complication of ileostomies in infants. Traditional conservative measures, including skin barriers, ointments, and agents to reduce bowel movements, initially may be helpful but not in all patients. The purpose of this case series was to describe a new and relatively ...
Han Chang Woo CW Division of Pediatric Cardiology, Department of Pediatrics, Congenital Heart Disease Center, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, - - 2013
Prolonging of the corrected QT interval (QTc) has been reported after cardiac surgery in some studies. However, there have not been many studies on infant open cardiac surgery for ventricular septal defect (VSD) repair. This study was performed to define the changes in QTc and to find related post-surgery factors ...
Yoo Suk Dong SD Department of Pediatrics, Pusan National University School of Medicine, Yangsan, - - 2013
To investigate the clinical characteristics and outcomes among infants and toddlers with failure to thrive (FTT). This retrospective study was done with 123 patients who had visited Pusan National University Children's Hospital during their first two years of life and had received an FTT diagnosis. We compared the clinical characteristics ...
Afroze Farzana F Clinical Services Centre, icddr,b, GPO Box 128, Dhaka 1000, - - 2013
A one month and twenty-five days old baby girl with problems of acute watery diarrhoea, severe dehydration, severe malnutrition, and reduced activity was admitted to the gastrointestinal unit of Dhaka Hospital of icddr,b. The differentials included dehydration, dyselectrolytaemia and severe sepsis. She was treated following the protocolized management guidelines of ...
Hasegawa Hisaya - - 2013
The breathing intolerance index (BITI) is used to justify ventilator use in adult patients with pulmonary or chest wall diseases in adults. BITI in ventilated patients were mostly at or above 0.15. The mean BITI of healthy adults in the upright sitting position and the supine position were 0.050 ±0.009 ...
Bojan Mirela - - 2013
Urine neutrophil gelatinase-associated lipocalin (uNGAL) has been shown to accurately predict and allow early detection of AKI, as assessed by an increase in serum creatinine in children and adults. The present study explores the accuracy of uNGAL for the prediction of severe AKI-related outcomes in neonates and infants undergoing cardiac ...
Klingenberg Claus - - 2013
To compare patient comfort in preterm infants treated with heated humidified high flow nasal cannulae (HHHFNC) versus nasal continuous positive airway pressure (NCPAP). Randomised cross-over trial (2×24 h). Single tertiary neonatal unit. 20 infants less than 34 weeks postmenstrual age treated with NCPAP due to mild respiratory illness. After parental ...
Rodrigues Regina Maria - - 2013
To investigate the influence of hypotonic parenteral hydration on serum and urinary sodium and osmolality in infants with moderate bronchiolitis. We studied 36 infants (mean age 3.7 ± 2.3 months), with a diagnosis of moderate bronchiolitis admitted to a paediatric emergency unit in São Paulo, Brazil. Patients received a standard ...
Dodsworth Charlotte - - 2013
Records were reviewed on all patients with mucopolysaccharidosis type II (Hunter syndrome) seen at a single institution from 1999 to 2013 to identify those with a history of neonatal intensive care. Eleven of 34 patients were in a neonatal intensive care unit and all had respiratory distress with 8 diagnoses ...
Williams Sophia N SN Pediatric Pulmonology/Allergy/Immunology, Miller Children's Hospital, Long Beach, University of California, - - 2014
Newly implemented newborn screening (NBS) programs in California have resulted in a large subset of patients in whom at least two cystic fibrosis transmembrane conductance regulator (CFTR) mutations are identified, but subsequent sweat chloride analysis reveals normal or indeterminate values. These patients are diagnosed with CFTR-Related Metabolic Syndrome (CRMS). However, ...
Kiryazov Kiril - - 2013
Topical ocular medications have been widely prescribed and successfully used in children for the management of different ophthalmic disorders. We present 2 infants admitted to our pediatric intensive care unit who developed altered state of consciousness, hypotonia, hypothermia, bradycardia, and apnea after instillation of ophthalmic drops. The second infant also ...
Pirojsakul Kwanchai K Division of Nephrology, Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. - - 2013
Ornithine transcabamylase (OTC) deficiency is the most common and severe form of abnormal urea synthesis. It can result in hyperammonemia, severe neurologic manifestation, brain edema, and early death. Rapid removal of ammonia by hemodialysis can decrease mortality and morbidity in the patients with severe increase of ammonia levels. However hemodialysis ...
Miller Thomas A - - 2013
The risk of necrotizing enterocolitis (NEC) in association with congenital heart disease is highest in patients with hypoplastic left heart syndrome (HLHS). Within the HLHS population, however, risk factors for NEC remain debated. We hypothesized that some infants with HLHS have vascular changes that contribute to gut hypoperfusion independent of ...
Pugni Lorenza L NICU, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Via Commenda 12, 20122, Milan, Italy, - - 2014
Severe hypertriglyceridemia (sHTG) (plasma triglyceride level > 10 mmol/L) due to lipoprotein lipase (LPL) deficiency is a known risk factor for acute pancreatitis. A 23-day-old male with sHTG was admitted to the Neonatal Intensive Care Unit for plasmapheresis being at high risk for acute pancreatitis. Given the potential hazard of ...
Brito Maria A - - 2013
Kernicterus is an irreversible brain damage caused by bilirubin deposition in selective brain regions. Sick and preterm infants with hyperbilirubinemia are particularly susceptible to the condition. We studied autopsied brain tissue from a premature female infant with kernicterus with a bilirubin:albumin molar ratio of 1.0, hypoxia, acidosis, and seizures. The ...
Aarts Lonneke A M LA Department of Pediatrics, Máxima Medical Center, Veldhoven, The Netherlands. Electronic address: - - 2013
Presently the heart rate is monitored in the Neonatal Intensive Care Unit with contact sensors: electrocardiogram or pulse oximetry. These techniques can cause injuries and infections, particularly in very premature infants with fragile skin. Camera based plethysmography was recently demonstrated in adults as a contactless method to determine heart rate. ...
Lozinsky Adriana Chebar - - 2013
To review the literature for clinical data on infants with allergic or eosinophilic colitis. MEDLINE search of all indexes was performed using the words "colitis or proctocolitis and eosinophilic" or "colitis or proctocolitis and allergic" between 1966 and February of 2013. All articles that described patients' characteristics were selected. A ...
Lee Ji-Hyuk - - 2013
Cow's milk protein (CMP)-specific IgG4 responses and the efficacy of oral desensitization in infants with cow's milk allergy (CMA) warrant more clarification. To explore whether CMP-specific IgG4 responses develop during infancy and whether regular CM exposure is efficacious for inducing a CMP-specific IgG4 response accompanying CM desensitization in 7- to ...
Ozer Esra Arun EA Department of Neonatology, Tepecik Teaching and Research Hospital, Izmir, - - 2013
Pneumothorax in newborns may result in a significant mortality and morbidity. To predict who will survive or die is of great importance in the clinical management. The aim of this study is to address whether assessment of pneumothorax size on chest X-ray may be a predictor of prognosis in newborns ...
Monajemzadeh Maryam M Department of Pathology, Tehran University of Medical Sciences, Tehran, Iran ; Infectious Disease Research Center, Children's Medical Center Hospital, Tehran University of Medical Sciences, Tehran, - - 2013
Alpha1-antitrypsin deficiency (A1ATD) is the most important indication for liver transplantation in children. The gene frequencies vary in different ethnic groups. In the present study, we attempt to determine the frequencies of the most common defective alleles, Z and S, in Iranian children suffering from idiopathic neonatal cholestasis. Eighty-seven infants ...
Galambos Csaba C 1 Department of - - 2013
Bronchopulmonary dysplasia (BPD) is the chronic lung disease of infancy that occurs in premature infants after oxygen and ventilator therapy for acute respiratory disease at birth. Despite improvement in current therapies, the clinical course of infants with BPD is often characterized by marked hypoxemia that can become refractory to therapy. ...
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