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Soares Daniele de Almeida - - 2012
Exploratory behaviors of 9 late preterm infants and 10 full-term infants were evaluated longitudinally at 5, 6 and 7months of age. Eight exploratory behaviors were coded. The preterm infants mouthed the object less and had delayed gains in Waving compared to the full-term infants.
Fishbein Mark - - 2012
Background: Symptoms of infantile gastroesophageal reflux disease (GERD) may overlap with oropharyngeal dysphagia, but the evaluation and treatment of these conditions vary greatly. In this investigation, the incidence of oropharyngeal dysphagia in infants with GERD-like symptoms is determined. Materials and Methods: A retrospective chart review was performed on infants referred ...
Brennan Tara - - 2012
Laryngomalacia is the most common cause of neonatal stridor, accounting for up to 60% of cases [1]. Less common causes of neonatal stridor include subglottic or tracheal stenosis, or congenital masses of the upper airway. Neonates with an identified congenital etiology of symptomatic upper airway obstruction often have synchronous airway ...
Azmeh Roua - - 2012
BACKGROUND: Children may present in early infancy for evaluation of decreased visual responsiveness. Most such infants have systemic or ocular abnormalities that explain their poor fixation and tracking. Some infants, however, have no other medical or ocular problems. This study evaluated prognostic factors in this latter group of otherwise normal ...
Bertino E - - 2012
Preterm infantsÂ’ survival has greatly increased in the last few decades thanks to the improvement in obstetrical and neonatal care. The correct evaluation of postnatal growth of these babies is nowadays of primary concern, although the definition of their optimal postnatal growth pattern is still controversial. Concerns have also been ...
Bertino E - - 2012
Auxological evaluation of the newborn should be based on accurate anthropometry at birth and a reliable estimate of gestational age (GA). However, a comprehensive evaluation of the neonate should consider not only anthropometric traits at birth, but also fetal ultrasound biometry and Doppler velocimetry. Many charts have been proposed, but ...
Yaji Prabhat Radhakrishna PR Department of General Surgery, Vijayangara Institute of Medical Sciences, Bellary, - - 2013
Gastric teratoma is a rare tumor, accounting for less than 1 % of all teratomas in infants & children. To date, only about 102 cases have been reported in the literature. A 10 month old infant was brought with a history of upper abdominal mass which was otherwise asymptomatic. On evaluation it ...
Hunter Sharon K - - 2012
Prenatal maternal anxiety has detrimental effects on the offspring's neurocognitive development, including impaired attentional function. Antidepressants are commonly used during pregnancy, yet their impact on offspring attention and their interaction with maternal anxiety has not been assessed. The authors used P50 auditory sensory gating, a putative marker of early attentional ...
Singer Lynn T LT Department of Environmental Health Sciences, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA. - - 2012
3,4-methylenedioxymethamphetamine (MDMA) or "Ecstasy" is one of the most widely used illicit recreational drugs among young adults. MDMA is an indirect monoaminergic agonist and reuptake inhibitor that primarily affects the serotonin system. Preclinical studies in animals have found prenatal exposure related to neonatal tremors and long-term learning and memory impairments. ...
Kontomanolis E N - - 2012
The ductus venosus is a short vessel, present in the newborn infant on the dorsal surface of the liver, connecting the portal and umbilical circulation with the inferior vena cava. Agenesis of the duct is a rare anomaly. A 28-year-old woman was referred to our department for the first trimester ...
Cresi Francesco - - 2012
The clinical significance of weakly acidic reflux in infants is unclear. Skin conductance is a novel not-invasive method to evaluate discomfort. The aim of our study was to evaluate reflux-induced discomfort in infants with gastroesophageal reflux disease using simultaneously combined skin conductance and esophageal multichannel intraluminal impedance and pH monitoring. ...
Hamilton Kimberly M - - 2011
Encephaloceles are acquired or congenital defects in which intracranial contents protrude through a defect in the calvaria. The embryogenesis of these lesions is incompletely understood. The vast majority of lesions occur at or near the anatomical midline. The authors present an extremely rare case of a laterally oriented, pathologically proven ...
Shah Vibhuti - - 2011
Glycerin laxatives are often prescribed in the neonatal population for meconium evacuation and to promote enteral feeding. However, the literature regarding their effectiveness has not been systematically reviewed. To assess the effectiveness of glycerin enema or suppository in preventing feeding intolerance in preterm infants at ≤32 weeks' gestational age or ...
Courville Amber B - - 2011
DHA (22 : 6n-3) in pregnancy has previously been shown to benefit infant brain and retinal development. Fatty acid consumption during pregnancy may also have an impact on infant adipose tissue development. The objective of the present study was to assess the prenatal impact of a DHA-containing functional food (DHA-FF) ...
Kim Joon Sik - - 2011
In the pediatric literature, excessive crying has been reported solely in association with 3-month colic and is described, if at all, as unexplained crying and fussing during the first 3 months of life. The bouts of crying are generally thought to be triggered by abdominal colic (over-inflation of the still ...
Ovono Abessolo Félix - - 2011
Objectives: To study the maturation of breast milk by the course of immunoglobulins A, G and M during the first three weeks of breast feeding. Material and methods: This longitudinal and prospective survey took place from August to October, 2007, in Libreville, the capital of Gabon. The population comprised women ...
Belderbos Mirjam E - - 2011
Background: Respiratory syncytial virus (RSV) is the most important pathogen causing severe lower respiratory tract infection (LRTI) in infants. Epidemiologic and basic studies suggest that vitamin D may protect against RSV LRTI. Objective: To determine the association between plasma vitamin D concentrations at birth and the subsequent risk of RSV ...
van den Broek Paul P Dept. of Pediatrics, Div. of Neonatology, University Medical Center Groningen, Hanzeplein 1, 9700 RB, The Netherlands. - - 2011
Sepsis is associated with an increased production of oxidant species and a decrease in endogenous antioxidant defenses. Mortality is high, especially when endotoxins are involved, e.g., in infants with Gram-negative sepsis. Yet, chronic as well as acute unconjugated hyperbilirubinemia has been shown to protect against endotoxin-induced shock in vivo in ...
Chin Brian - - 2011
A survival regression model that allows for spatially correlated random effects is used to predict the hazard of dying among 12,714 children born between 1996 and 2006 in Nepal. The maps of fitted hazard rates show that even after accounting for individual and community-level covariates, a residual spatial pattern in ...
Kambia Nicolas - - 2011
Background: Plasticizers such as di(2-ethylhexyl) phthalate (DEHP) are added to polyvinyl chloride (PVC) to confer flexibility. However, DEHP is associated with reproductive disorders in humans. Because of its noncovalent bond to the PVC matrix, this plasticizer tends to leach easily. Infants and children undergoing cyclic, long-term parenteral nutrition (PN) could ...
Okogbule-Wonodi Adora C AC Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland 21201, - - 2011
The study objective was to determine whether Ureaplasma respiratory tract colonization of preterm infants <33 wk gestation is associated with an increased risk for necrotizing enterocolitis (NEC). One or more tracheal or nasopharyngeal aspirates for Ureaplasma culture and PCR were obtained during the first week of life from 368 infants ...
Nakamura Ikeda Rie - - 2011
OBJECTIVE: to assess the bed climate of infants in their homes in Japan. DESIGN: descriptive, exploratory, non-experimental research design. SETTING: the data were collected at the participants' homes under normal circumstances. PARTICIPANTS: nineteen healthy infants between the ages of two and five months. Their mothers, who joined a parenting class ...
Deng Bo - - 2011
Sixty breast milk samples were collected in Shenzhen, China from July to November in 2007. The samples were analyzed of the concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs). The range of upper-bound for ∑TEQ-(PCDD/Fs+PCBs) in the samples was 4.10-35.3pgTEQg(-1) lipid (median: 10.6pgTEQg(-1) lipid; mean: 11.9pgTEQg(-1) ...
Savino Francesco F Department of Pediatrics, Regina Margherita Children's Hospital, Piazza Polonia 94-10126, Turin, Italy. - - 2011
To test if total ghrelin is present in infant formulas. Using a radioimmunoassay, we measured total ghrelin concentrations in 19 samples of commercial infant formulas and in 20 samples of human milk. We also determined ghrelin concentration in the serum of infants and lactating mothers. Ghrelin concentrations were significantly higher ...
Castellote Cristina - - 2011
Human breast milk is the ideal nutrition for the newborn, and in addition to its nutritional contribution, necessary for infant growth and development, it contains various immune bioactive factors that confer some of the numerous beneficial effects of breastfeeding. The current study analyzed the concentrations of IgA, growth factors such ...
Zhang Lei - - 2011
Seven polybrominated diphenyl ethers (PBDEs) congeners (BDE-28, BDE-47, BDE-99, BDE-100, BDE-153, BDE-154 and BDE-183) and six indicator polychlorinated biphenyls (PCBs) congeners (CB-28, CB-52, CB-101, CB-138, CB-153 and CB-180) were measured in 24 pooled human milk samples comprised of 1237 individual samples from 12 provinces in China. The samples were taken ...
Tov Amir Ben - - 2011
Abstract Background: Parathyroid hormone-related protein (PTHrP) has the ability to activate parathyroid hormone receptors and cause hypercalcemia. In a previous study we have demonstrated high concentrations of PTHrP in both term and preterm human milk (HM). PTHrP intestinal absorption and its influence upon calcium homeostasis of the preterm infant have ...
Kinjo Tadamune - - 2011
BACKGROUND: Cytokines and chemokines during perinatal period may involve the neurological development of newborns. AIMS: We investigated the association of circulating chemokines during neonatal period with the outcome of premature infants. STUDY DESIGN: The prospective study enrolled 29 very low birth weight (<1500g) and appropriate-for-date infants having no underlying diseases. ...
Schiess Sonia A - - 2011
Background: Little information is available on infants' age at first introduction of potentially allergenic foods as part of complementary feeding. We aimed to analyze age at the introduction of potentially allergenic foods in healthy term infants relative to recommendations in 5 European countries. Method: Recruitment was conducted from October 2002 ...
Lessa Marques Ana Lúcia Silveira - - 2011
High incidences of Gram-negative bacteria are found in neonatal nosocomial infections. Our aim was to investigate placental transmission of IgG reactive with LPS from Klebsiella pneumoniae, Pseudomonas aeruginosa and Escherichia coli O111, O6 and O26. Total and LPS-specific IgM and IgG were determined in 11 maternal/umbilical-cord sera aged ≤33 weeks ...
Basavanna Girishkumar G Fermentation Technology and Bioengineering Department, Central Food Technological Research Institute, Mysore, Karnataka - - 2013
Functional properties of the Lactobacillus fermentum CFR 2195, isolated from healthy infant feces have been evaluated. The adherence of L. fermentum to HT-29 and Caco-2 cell-lines were found to be 197.66 ± 15.62 and 100.33 ± 15.69 per 100 cells, respectively. The effect of different concentrations of FOS (0.5, 1.0, 1.5, 2.0 and 2.5%) ...
Owino Victor O - - 2011
Lipid-based ready-to-use foods are currently used for infant feeding, but their potential effect on breast-milk intake is not well documented. The objective was to assess the breast-milk intake of 9-10-mo-old infants given either a ready-to-use complementary food (RUCF) paste or a standard corn-soy blend (UNIMIX) porridge in South Kivu, Democratic ...
Benzing Jörg - - 2011
Context: Copeptin is a stable by-product of arginine-vasopressin synthesis and reflects its secretion by the pituitary. Objective: The objective of the study was to investigate perinatal factors affecting copeptin concentrations in preterm infants at birth and at 3 d of life. Design and Setting: This was a prospective cross-sectional study ...
Wikström Sverre - - 2011
Objectives: To investigate if Paco(2) and plasma glucose levels affect electrocortical activity. Methods: Ours was an observational study of 32 infants with a gestational age of 22 to 27 weeks. We performed simultaneous single-channel electroencephalogram (EEG) and repeated blood gas/plasma glucose analyses during the first 3 days (n = 247 ...
Cohen-Wolkowiez M M Department of Pediatrics, Duke University, Durham, North Carolina, USA. - - 2011
Candida infections are common and often fatal in infants and neonates. Anidulafungin has excellent activity against Candida species, but the pharmacokinetics (PK) and safety of the drug in infants and neonates are unknown. The object of our study was to determine the PK and safety of anidulafungin in infants and ...
Fromme H - - 2011
Phthalates have long been used as plasticizers to soften plastic products and, thus, are ubiquitous in modern life. As part of the Bavarian Monitoring of Breast Milk (BAMBI), we aimed to characterize the exposure of infants to phthalates in Germany. Overall, 15 phthalates, including di-2-ethylhexyl phthalate (DEHP), di-n-butyl phthalate (DnBP), ...
Salman Sam - - 2011
PURPOSE: The aim of this investigation was to demonstrate that nonlinear mixed-effects population pharmacokinetic (PK) modeling can be used to evaluate data from studies of drug transport/excretion into human milk and hence to estimate infant exposure. METHODS: A sparse dataset from a previously published study of the use of oral ...
Vigh Eva - - 2011
The presence of macrophage migration inhibitory factor (MIF) in breast milk has been reported before, but its concentration at distinct phases of lactation has not yet been delineated. We have measured the MIF content in the aqueous phase of 63 milk samples from 21 mothers at postpartum days 5, 12 ...
Karatas Zehra - - 2011
The aim of this study was to evaluate the changes in the ghrelin, leptin, and fat levels in the foremilk and hindmilk and the possible relationship between these levels with the age and growth of term healthy infants. Sixty-two babies were subdivided (according to their nutrition) into breastfed (BF), formula-fed ...
Imamura Takashi - - 2011
Objective. To examine the expression levels of glucocorticoid receptor (GR) isoforms in peripheral blood mononuclear cells (PBMCs) and serum cortisol levels in cord blood from term infants. Methods. The study population consisted of 172 term infants who were delivered from healthy pregnant women. GRalpha and GRbeta expression levels, and serum cortisol level ...
Ng Pak C - - 2011
The normal range of serum cortisol concentrations and the appropriate levels of circulating cortisol in different clinical situations in preterm infants are not well defined. This study aimed to evaluate the impact of perinatal factors on circulating cortisol levels in preterm infants, and to create a quantitative model that could ...
Boyce Philip M - - 2011
OBJECTIVE: Duloxetine is an efficacious antidepressant; however, its safety during the perinatal period is uncertain. The objective of this study was to assess the transfer across the placenta and provide data on infant exposure to duloxetine via breast milk. METHODS: A multiparous 31-year-old woman with recurrent melancholic depression had responded ...
Siltanen Mirjami - - 2011
BACKGROUND: Immunologic pathways are primed in early life. Preterm birth can influence this process and thereby affect whether a person will have atopy later in life. Previous studies on the effects of preterm birth on atopy in adulthood have been inconclusive and limited to children or subjects born moderately preterm. ...
Goedhart Geertje - - 2011
BACKGROUND: The etiology of excessive infant crying is largely unknown. We hypothesize that excessive infant crying may have an early nutritional origin during fetal development. AIMS: This study is the first to explore whether (1) maternal vitamin B-12 and folate status during pregnancy are associated with excessive infant crying, and ...
Hansen-Pupp Ingrid - - 2011
Context: IGF-I and IGF binding protein-3 (IGFBP-3) are essential for growth and maturation of the developing brain. Objective: The aim of this study was to evaluate the association between postnatal serum concentrations of IGF-I and IGFBP-3 and brain volumes at term in very preterm infants. Design: Fifty-one infants with a ...
Drover James R - - 2011
BACKGROUND: Studies investigating cognitive outcomes following docosahexaenoic acid (DHA) supplementation of infant formula yield conflicting results, perhaps due to inadequate dietary concentrations. AIM: To determine the optimal DHA concentration in term formula to support cognitive maturation. DESIGN: This was a double-masked, randomized, controlled, prospective trial. A total of 181 infants ...
Pedersen Mark E - - 2011
The aim of the present pilot study was to evaluate the safety and clinical application of intraperitoneal microdialysis (MD) in preterm infants operated on for necrotizing enterocolitis (NEC). Fourteen infants underwent MD. Two were excluded from analysis: 1 because of catheter malfunction and 1 because of fatal outcome immediately after ...
Berle Jan Øystein - - 2011
BACKGROUND: The treatment of breastfeeding mothers with depression raises several dilemmas, including the possible risk of drug exposure through breast milk for the infant. This article provides background information and presents practical advice and recommendations for the clinician dealing with the treatment of depression and related disorders in the postpartum ...
Georgiou Harry M - - 2011
OBJECTIVE: The purpose of this study was to investigate whether birth of a small-for-gestational-age (SGA) baby (birthweight, <10th percentile) is preceded by altered maternal serum cytokine profiles at early pregnancy, compared with control babies (birthweight, 30-80th percentile). STUDY DESIGN: A retrospective case-control study of maternal serum collected prospectively across 7-10 ...
Han Young-Hee - - 2011
To evaluate the effect of feeding methods on growth and zinc nutritional status of infants early in life, we monitored from birth to 36 months in 51 infants who were exclusively fed human milk (HM, n = 20), casein-based formula (CBF, n = 12), or soy-based formula (SBF, n = ...
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