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Scott David R - - 2013
We describe a 2-year old boy with consanguineous parents who recently emigrated from India and presented with oral ulcers and lymphadenopathy. He also had a history of recurrent fevers, polyarticular arthritis, chronic diarrhea, failure to thrive, and developmental delay. Infectious workup revealed herpes simplex virus 1 viremia and radiological evaluation ...
Aydin Mustafa - - 2013
We read with great interest the article by Prempunpong et al (1) that evaluated the effect of the therapeutic hypothermia (TH) on fluid balance and incidence of hyponatraemia in newborns with moderate to severe hypoxic-ischemic encephalopathy (HIE). The authors suggest that implementation of TH increases fluid overload and incidence of hyponatraemia. ...
Inchingolo R - - 2013
Fetal hydronephrosis is the most common anomaly detected on antenatal ultrasound examination, affecting 1-5% pregnancies. A new management in mild antenatal renal pelvis dilatation (ARPD), using a technique based on both morphological and dynamical evaluation. Prospective study conducted during a 36-months period in 180 consecutive newborns referred as having mild ...
Smit Marrit - - 2013
to evaluate the feasibility of using pulse oximetry (PO) for evaluating infants born in community-based midwifery care. a prospective, observational study of infants born after midwifery supervised (home) births. 27 midwives from seven practices providing primary care in (home) births used PO at birth or the early puerperal period over ...
Kayıran Petek Genc - - 2013
Abstract Contrary to traditional belief, breast milk is not a sterile fluid, even in healthy women. Breast milk may contain pathogenic bacteria that could cause serious infections especially in premature infants. There is no recommendation to evaluate breast milk routinely for pathogenic bacteria. However discontinuation of breastfeeding is not recommended ...
St Aubin Melissa - - 2013
There is no consensus on the extent and mode of postnatal imaging after a diagnosis of prenatal hydronephrosis. We validated the protocol of our practice, which parallels current Society for Fetal Urology (SFU) recommendations, in limiting voiding cystourethrogram, while examining its impact on the incidence of febrile urinary tract infections. ...
Abdel-Salam Z - - 2013
This study focuses on the use of laser-induced breakdown spectroscopy (LIBS) for the evaluation of the nutrients in maternal milk and some commercially available infant formulas. The results of such evaluation are vital for adequate and healthy feeding for babies during lactation period. Laser-induced breakdown spectroscopy offers special advantages in ...
Vergano Samantha A SA Section of Biochemical Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, - - 2013
Prompt ascertainment is crucial for the management of hyperammonemic infants. Because these patients are rare and recognition of hyperammonemia is often delayed, we designed and implemented an electronic medical record (EMR)-based tool to assist physicians in the detection of hyperammonemia. We retrospectively evaluated the hospitalizations of prior hyperammonemic infants to ...
Arayici Sema - - 2013
We read with great interest the paper by Dargaville et al. whose objective was to evaluate the fluid recovery during lung lavage in meconium aspiration syndrome (MAS) (1). They found that heightened recovery of lavage fluid, and thus meconium, is associated with improved respiratory outcome after lung lavage in ventilated infants ...
Serafini Fausta - - 2013
Bifidobacteria are extensively exploited by the food industry as health-promoting microorganisms. However, very little is known about the molecular mechanisms responsible for these beneficial activities, or the molecular players that sustain their ability to colonize and persist within the human gut. Here, we have investigated the enteric adaptation features of ...
Berk David R - - 2013
The natural history of inherited epidermolysis bullosa (EB) varies significantly across subtypes. When confronted with an infant suspected to have EB, rapidly determining the type and subtype is critical in counselling families accurately about the infant's diagnosis and prognosis. Although transmission electron microscopy (TEM) has been considered the criterion standard ...
Staat Mary Allen - - 2013
Prevalence of polymerase chain reaction-confirmed respiratory syncytial virus (RSV) among infants presenting to 31 US emergency departments with lower respiratory infection or apnea (N=4172) was evaluated outside the traditional RSV season (September-October and April-May) relative to January-February. The Mid-Atlantic and Southeast (HHS regions 3 [Philadelphia] and 4 [Atlanta]), demonstrated positivity ...
Gandhi Bheru - - 2013
OBJECTIVE: To determine whether resuscitation teams can better maintain newborn transitional oxygen saturation (SpO(2)) values within a prespecified target range using a graphical display of the targets and real-time SpO(2) data compared with using only numerical oximeter values. STUDY DESIGN: Preterm neonates were enrolled in this prospective cohort evaluation of ...
Puopolo Karen M - - 2013
PURPOSE OF REVIEW: Neonatal early-onset sepsis (EOS) is a very low-incidence, but potentially fatal condition among term and late preterm newborns. EOS algorithms based on risk-factor threshold values result in evaluation and empiric antibiotic treatment of large numbers of uninfected newborns, leading to unnecessary antibiotic exposures and maternal/infant separation. Ideally, ...
Narvaez-Arzate Ricardo V - - 2013
Abstract Objectives. To determine the incidence of congenital cytomegalovirus (CMV) infection and the frequency of postnatal infection in a Neonatal Intensive Care Unit (NICU). Methods. Urine samples of 135 infants who were admitted to the NICU during a six month period were evaluated to detect CMV using a nested PCR ...
Li Zhiping - - 2013
OBJECTIVES: To develop population pharmacokinetic (PK) models for piperacillin/tazobactam in neonates and infants of less than 2 months of age in order to determine the appropriate dosing regimen and provide a rational basis for the development of preliminary dosing guidelines suitable for this population. METHODS: A two-stage, open-label study was conducted ...
Kutuk Mehmet Serdar - - 2013
BACKGROUND: This study aimed to evaluate postnatal outcome of fetuses affected by nonprogressive, isolated, mild (≥10 and ≤12 mm) borderline ventriculomegaly (BVM). METHODS: We studied 25 consecutive fetuses with BMV and evaluated patients' characteristic, ultrasonographic findings, and the neurodevelopmental outcome at age ≥24 months. RESULTS: The mean gestational age at diagnosis was ...
Weinbauer Gerhard F - - 2013
The enhanced pre- and postnatal (ePPND) study design has been developed in response to new scientific knowledge and subsequent guideline changes [ICH M3(R2) and ICH S6(R1)]. The changes in study design were basically driven by the experiences obtained during preclinical development of biopharmaceuticals. The standard ePPND concept does not apply ...
Kanakogi Yasuhiro - - 2013
Despite its essential role in human coexistence, the developmental origins and progression of sympathy in infancy are not yet fully understood. We show that preverbal 10-month-olds manifest sympathetic responses, evinced in their preference for attacked others according to their evaluations of the respective roles of victim, aggressor, and neutral party. ...
Coppa Giovanni Valentino - - 2013
Recently, a complete characterization and detailed evaluation of the glycosaminoglycans of human milk were performed. The total glycosaminoglycans content in milk from healthy mothers having delivered term or preterm newborns showed a constant pattern which was essentially composed of two main polysaccharides: chondroitin sulfate (60-70%) and heparin (30-40%). Moreover, considerable ...
Hasvold J - - 2013
Neonatal sepsis is a significant cause of morbidity and mortality among term and preterm infants. Ampicillin and gentamicin are standard empiric therapy for early onset sepsis. Four cases of neonatal sepsis secondary to Escherichia coli (E. coli) found to be gentamicin resistant occurred within a five week period in one ...
O'Neill Marie S MS University of Michigan School of Public Health, Ann Arbor, MI, USA. - - 2013
Preterm birth is one of the leading causes of perinatal mortality and is associated with long-term adverse health consequences for surviving infants. Preterm birth rates are rising worldwide, and no effective means for prevention currently exists. Air pollution exposure may be a significant cause of prematurity, but many published studies ...
Bagci Soyhan - - 2012
PURPOSE: The aim of this pilot study was to evaluate the diagnostic value of pleth variability index (PVI) to predict fluid responsiveness in newborn infants during surgery. METHODS: PVI was continuously recorded in 29 mechanically ventilated newborn infants during surgery, and episodes of clinically indicated volume expansion (VE) (≥10 ml/kg in ...
Martinelli Roberta Lopes de Castro - - 2012
An experimental protocol model for frenulum evaluation was first designed, and administered to ten infants in 2010. After obtaining the data and statistical analysis, the protocol was re-designed and administered to 100 infants. The aim of this study is to present an efficient and effective lingual frenulum protocol with scores ...
Whiting Terry L - - 2012
Cattle death by starvation is a persistent annual event in Manitoba. Herds with more than 10% overwinter death loss are usually identified in the late winter or early spring. Field and postmortem findings suggest that there is complete mobilization of fat followed by inability to maintain adequate thermoregulation and death ...
Soares Daniele de Almeida - - 2012
Exploratory behaviors of 9 late preterm infants and 10 full-term infants were evaluated longitudinally at 5, 6 and 7months of age. Eight exploratory behaviors were coded. The preterm infants mouthed the object less and had delayed gains in Waving compared to the full-term infants.
Fishbein Mark - - 2012
Background: Symptoms of infantile gastroesophageal reflux disease (GERD) may overlap with oropharyngeal dysphagia, but the evaluation and treatment of these conditions vary greatly. In this investigation, the incidence of oropharyngeal dysphagia in infants with GERD-like symptoms is determined. Materials and Methods: A retrospective chart review was performed on infants referred ...
Brennan Tara - - 2012
Laryngomalacia is the most common cause of neonatal stridor, accounting for up to 60% of cases [1]. Less common causes of neonatal stridor include subglottic or tracheal stenosis, or congenital masses of the upper airway. Neonates with an identified congenital etiology of symptomatic upper airway obstruction often have synchronous airway ...
Azmeh Roua - - 2012
BACKGROUND: Children may present in early infancy for evaluation of decreased visual responsiveness. Most such infants have systemic or ocular abnormalities that explain their poor fixation and tracking. Some infants, however, have no other medical or ocular problems. This study evaluated prognostic factors in this latter group of otherwise normal ...
Bertino E - - 2012
Preterm infants’ survival has greatly increased in the last few decades thanks to the improvement in obstetrical and neonatal care. The correct evaluation of postnatal growth of these babies is nowadays of primary concern, although the definition of their optimal postnatal growth pattern is still controversial. Concerns have also been ...
Bertino E - - 2012
Auxological evaluation of the newborn should be based on accurate anthropometry at birth and a reliable estimate of gestational age (GA). However, a comprehensive evaluation of the neonate should consider not only anthropometric traits at birth, but also fetal ultrasound biometry and Doppler velocimetry. Many charts have been proposed, but ...
Yaji Prabhat Radhakrishna PR Department of General Surgery, Vijayangara Institute of Medical Sciences, Bellary, - - 2013
Gastric teratoma is a rare tumor, accounting for less than 1 % of all teratomas in infants & children. To date, only about 102 cases have been reported in the literature. A 10 month old infant was brought with a history of upper abdominal mass which was otherwise asymptomatic. On evaluation it ...
Hunter Sharon K - - 2012
Prenatal maternal anxiety has detrimental effects on the offspring's neurocognitive development, including impaired attentional function. Antidepressants are commonly used during pregnancy, yet their impact on offspring attention and their interaction with maternal anxiety has not been assessed. The authors used P50 auditory sensory gating, a putative marker of early attentional ...
Singer Lynn T LT Department of Environmental Health Sciences, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA. - - 2012
3,4-methylenedioxymethamphetamine (MDMA) or "Ecstasy" is one of the most widely used illicit recreational drugs among young adults. MDMA is an indirect monoaminergic agonist and reuptake inhibitor that primarily affects the serotonin system. Preclinical studies in animals have found prenatal exposure related to neonatal tremors and long-term learning and memory impairments. ...
Kontomanolis E N - - 2012
The ductus venosus is a short vessel, present in the newborn infant on the dorsal surface of the liver, connecting the portal and umbilical circulation with the inferior vena cava. Agenesis of the duct is a rare anomaly. A 28-year-old woman was referred to our department for the first trimester ...
Cresi Francesco - - 2012
The clinical significance of weakly acidic reflux in infants is unclear. Skin conductance is a novel not-invasive method to evaluate discomfort. The aim of our study was to evaluate reflux-induced discomfort in infants with gastroesophageal reflux disease using simultaneously combined skin conductance and esophageal multichannel intraluminal impedance and pH monitoring. ...
Hamilton Kimberly M - - 2011
Encephaloceles are acquired or congenital defects in which intracranial contents protrude through a defect in the calvaria. The embryogenesis of these lesions is incompletely understood. The vast majority of lesions occur at or near the anatomical midline. The authors present an extremely rare case of a laterally oriented, pathologically proven ...
Shah Vibhuti - - 2011
Glycerin laxatives are often prescribed in the neonatal population for meconium evacuation and to promote enteral feeding. However, the literature regarding their effectiveness has not been systematically reviewed. To assess the effectiveness of glycerin enema or suppository in preventing feeding intolerance in preterm infants at ≤32 weeks' gestational age or ...
Courville Amber B - - 2011
DHA (22 : 6n-3) in pregnancy has previously been shown to benefit infant brain and retinal development. Fatty acid consumption during pregnancy may also have an impact on infant adipose tissue development. The objective of the present study was to assess the prenatal impact of a DHA-containing functional food (DHA-FF) ...
Kim Joon Sik - - 2011
In the pediatric literature, excessive crying has been reported solely in association with 3-month colic and is described, if at all, as unexplained crying and fussing during the first 3 months of life. The bouts of crying are generally thought to be triggered by abdominal colic (over-inflation of the still ...
Ovono Abessolo Félix - - 2011
Objectives: To study the maturation of breast milk by the course of immunoglobulins A, G and M during the first three weeks of breast feeding. Material and methods: This longitudinal and prospective survey took place from August to October, 2007, in Libreville, the capital of Gabon. The population comprised women ...
Belderbos Mirjam E - - 2011
Background: Respiratory syncytial virus (RSV) is the most important pathogen causing severe lower respiratory tract infection (LRTI) in infants. Epidemiologic and basic studies suggest that vitamin D may protect against RSV LRTI. Objective: To determine the association between plasma vitamin D concentrations at birth and the subsequent risk of RSV ...
van den Broek Paul P Dept. of Pediatrics, Div. of Neonatology, University Medical Center Groningen, Hanzeplein 1, 9700 RB, The Netherlands. - - 2011
Sepsis is associated with an increased production of oxidant species and a decrease in endogenous antioxidant defenses. Mortality is high, especially when endotoxins are involved, e.g., in infants with Gram-negative sepsis. Yet, chronic as well as acute unconjugated hyperbilirubinemia has been shown to protect against endotoxin-induced shock in vivo in ...
Chin Brian - - 2011
A survival regression model that allows for spatially correlated random effects is used to predict the hazard of dying among 12,714 children born between 1996 and 2006 in Nepal. The maps of fitted hazard rates show that even after accounting for individual and community-level covariates, a residual spatial pattern in ...
Kambia Nicolas - - 2011
Background: Plasticizers such as di(2-ethylhexyl) phthalate (DEHP) are added to polyvinyl chloride (PVC) to confer flexibility. However, DEHP is associated with reproductive disorders in humans. Because of its noncovalent bond to the PVC matrix, this plasticizer tends to leach easily. Infants and children undergoing cyclic, long-term parenteral nutrition (PN) could ...
Okogbule-Wonodi Adora C AC Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland 21201, - - 2011
The study objective was to determine whether Ureaplasma respiratory tract colonization of preterm infants <33 wk gestation is associated with an increased risk for necrotizing enterocolitis (NEC). One or more tracheal or nasopharyngeal aspirates for Ureaplasma culture and PCR were obtained during the first week of life from 368 infants ...
Nakamura Ikeda Rie - - 2011
OBJECTIVE: to assess the bed climate of infants in their homes in Japan. DESIGN: descriptive, exploratory, non-experimental research design. SETTING: the data were collected at the participants' homes under normal circumstances. PARTICIPANTS: nineteen healthy infants between the ages of two and five months. Their mothers, who joined a parenting class ...
Deng Bo - - 2011
Sixty breast milk samples were collected in Shenzhen, China from July to November in 2007. The samples were analyzed of the concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs). The range of upper-bound for ∑TEQ-(PCDD/Fs+PCBs) in the samples was 4.10-35.3pgTEQg(-1) lipid (median: 10.6pgTEQg(-1) lipid; mean: 11.9pgTEQg(-1) ...
Savino Francesco F Department of Pediatrics, Regina Margherita Children's Hospital, Piazza Polonia 94-10126, Turin, Italy. - - 2011
To test if total ghrelin is present in infant formulas. Using a radioimmunoassay, we measured total ghrelin concentrations in 19 samples of commercial infant formulas and in 20 samples of human milk. We also determined ghrelin concentration in the serum of infants and lactating mothers. Ghrelin concentrations were significantly higher ...
Castellote Cristina - - 2011
Human breast milk is the ideal nutrition for the newborn, and in addition to its nutritional contribution, necessary for infant growth and development, it contains various immune bioactive factors that confer some of the numerous beneficial effects of breastfeeding. The current study analyzed the concentrations of IgA, growth factors such ...
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