Search Results
Results 201 - 250 of 808
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Larson Austin - - 2013
Topical anesthetics are commonly used in many health care settings and for many clinical conditions. However, there are a number of potential adverse effects associated with their use. Their widespread administration can convey a false sense of security and failure to appreciate possible complications. We present the case of an ...
Streimish Iris - - 2013
Objective To assess the sensitivity and specificity of neutrophil CD64 as a diagnostic marker for clinical sepsis (based on a hematologic score) and as an additional marker with hematologic parameters for culture-proven sepsis in neonates.Study Design Prospective observational cohort over 18 months in a single-center neonatal intensive care unit.Results Hematologic ...
Murguía-Peniche Teresa - - 2013
The interplay between microorganisms and the intestine of newborn infants is associated with diverse functional and clinical outcomes that result from the specific interactions among microbial communities, their products, and the unique characteristics of the gastrointestinal tract. Multiple mechanisms of action for infant formula ingredients with probiotic activity appear to ...
Bodilis Hélène - - 2013
Bordetella pertussis isolates that do not express pertactin (PRN) are increasing in regions where acellular pertussis vaccines have been used for >7 years. We analyzed data from France and compared clinical symptoms among infants <6 months old infected by PRN-positive or PRN-negative isolates. No major clinical differences were found between ...
Naing Zin - - 2013
AIM: Premature neonates represent a population highly vulnerable to infection. This study aims to profile viral colonisation of gut and the associated clinical manifestations among premature neonates admitted to a neonatal intensive care unit (NICU) in Australia. METHODS: In a cohort of 75 premature neonates born at less than 32 ...
Ciliberto Heather - - 2013
Two infants developed hyperpigmented curvilinear patches on the posterior heel after wearing heel-length socks. Both of the patient's lesions improved after discontinuing the use of the heel-length socks. Hyperpigmented patches called sock-line or mitten-line hyperpigmentation have been reported at sites of tight elastic bands from socks or mittens in infants ...
Emerenciano Mariana - - 2013
Acute leukaemia in early childhood - and mainly infant leukaemia (IL) - is characterized by acquired genetic alterations, most commonly by the presence of distinct MLL rearrangements (MLL-r). The aim of this study was to investigate possible correlations between clinical features and molecular analyses of a series of 545 childhood ...
Kovacs Christopher S - - 2013
Recent research efforts have focused on the roles that vitamin D may play in skeletal and non-skeletal health during pregnancy, lactation, and fetal or neonatal development. Animal and clinical studies have shown that the mother provides calcium to the fetus and neonate without requiring vitamin D, calcitriol, or the vitamin ...
Shehabi Asem A - - 2013
BACKGROUND: Colonization of infants with MRSA carried specific toxin genes especially PVL are a risk factor for subsequent infection during hospitalization. This prospective study investigated important epidemiological characteristics of Staphylococcus aureus colonizing the nares and intestines of Jordanian infants. METHODS: A total of 860 nasal and stool specimens were obtained ...
Burge D M - - 2013
Reports on the management and outcome of rare conditions, such as oesophageal atresia, are frequently limited to case series reporting single-centre experience over many years. The aim of this study was to identify all infants born with oesophageal atresia in the UK and Ireland to describe current clinical practice and ...
Katheria A C - - 2013
Objective:To evaluate the hemodynamic changes occurring after rescue surfactant dosing in relation to the clinical respiratory response in preterm infants with respiratory distress syndrome.Study Design:We studied 20 infants who received surfactant (poractant alfa) after failing continuous positive airway pressure (CPAP) beyond 2 h of life. Consecutive echocardiograms were performed before the ...
Amin Sachin C SC Department of Pediatrics, Division of Neonatology, Center for Neonatal and Pediatric Gastrointestinal Disease, University of Illinois at Chicago, 840 South Wood Street, CSB 1257, Chicago, IL 60612, - - 2013
Short bowel syndrome (SBS) is the most common cause of intestinal failure in infants. In neonates and young infants, necrotizing enterocolitis, gastroschisis, intestinal atresia, and intestinal malrotation/volvulus are the leading causes of SBS. Following an acute postsurgical phase, the residual gastrointestinal tract adapts with reorganization of the crypt-villus histoarchitecture and ...
Farhath Sabeena - - 2013
Abstract: Objective: To study the relationship between pepsinogen/pepsin in a mouth swab and clinical gastroesophageal reflux (GER) in preterm infants. Methods: Preterm infants [birth weight (BW) ≤ 2000 grams] on full enteral feeds were enrolled. Mouth swabs from cheek and below the tongue were collected 1, 2 and 3 hours ...
Dilena Robertino - - 2013
Congenital myasthenic syndromes are inherited disorders caused by various defects in neuromuscular transmission. Although the typical presentation is fatigable weakness with prominent cranial involvement, neonates can lack these hallmark manifestations, and in those with choline acetyltransferase gene mutations, basal electrophysiological testing can yield negative findings. The authors report the case ...
Woods Patricia - - 2013
AIMS: The aim of the study was to examine the prevalence and management of outborn babies with a post-natally confirmed diagnosis of transposition of the great arteries (TGA) requiring transport by the Newborn and Paediatric Emergency Transport Service (NETS), New South Wales during the epoch 1991-2010. METHOD: A retrospective audit ...
Gutteridge Kathryn - - 2013
This article follows the journey of Sandwell and West Birmingham Hospitals NHS Trust quest for improving normal birth outcomes for a complex and diverse population. The opportunities that led to commissioning a colocated and freestanding birth centre are explored and how the design was influenced by less clinical beliefs about ...
Aggarwal Arun K - - 2013
This study was conducted to evaluate the performance of World Health Organisation (WHO) verbal autopsy tool in determining major causes of neonatal deaths. From a tertiary care hospital and a government multispecialty hospital, the attending paediatricians ascertained a clinical cause of death for 371 neonatal deaths. Trained field workers conducted ...
Moayedoddin A - - 2013
Depression and anxiety are major causes of distress amongst parents during the perinatal period. Their pervasive effects on the parents' self-confidence, on the parent-infant relationship and on the child's development have been well documented. The aims of the present study were to describe the psychological characteristics of mothers consulting during ...
Galinsky Robert - - 2013
Preterm birth is a major cause of perinatal mortality and long-term morbidity. Chorioamnionitis is a common cause of preterm birth. Clinical chorioamnionitis, characterised by maternal fever, leukocytosis, tachycardia, uterine tenderness, and preterm rupture of membranes, is less common than subclinical/histologic chorioamnionitis, which is asymptomatic and defined by inflammation of the ...
Schmölzer Georg M - - 2013
The main indications for interhospital neonatal transports are radiographic studies (e.g., magnet resonance imaging) and surgical interventions. Specialized neonatal transport teams need to be skilled in patient care, communication, and equipment management and extensively trained in resuscitation, stabilization, and transport of critically ill infants. However, there is increasing evidence that ...
Johnson Patricia J - - 2013
Normal sa line (NS) bolus infusions are indicated during resuscitation of the newborn to treat hypovolemia and resulting lactic acidosis because of inadequate tissue perfusion. However, in the neonatal intensive care settings, NS bolus infusions are also used to treat clinical hypoperfusion in the absence of confirmed volume loss or ...
Turrentine Mark A - - 2013
Background. Infants born to mothers who are colonized with group B streptococcus (GBS) but received <4 hours of intrapartum antibiotic prophylaxis (IAP) are at-risk for presenting later with sepsis. We assessed if <4 hours of maternal IAP for GBS are associated with an increased incidence of clinical neonatal sepsis. Materials ...
McCowan Lesley M E - - 2013
Small for gestational age (SGA) infants comprise up to 50% of all stillbirths and a minority are detected before birth. We aimed to develop and validate early pregnancy predictive models for SGA infants. 5628 participants from SCOPE, a prospective study of nulliparous pregnant women, were interviewed at 15±1 weeks' gestation. ...
Ozkan Aybars - - 2013
Uncontaminated urine samples are indispensable to precisely diagnose urinary tract infections in new-borns or infants. Among many clinical interventions for urine collection are described, the most common noninvasive practice is using sterile bags, associated with significant contamination of samples. In children, however, invasive methods i.e. catheterization, are generally needed for ...
Lista Gianluca - - 2013
Preterm infants with RDS need adequate resuscitation maneuvers and appropriate timing of surfactant replacement but about the latter there is not an universal consensus. A correct evaluation should consider at the same time the administration of antenatal steroids, the radiological criteria, the clinical presentation, the FiO2 level, OI and a/ApO2.
Vaccari Sabina - - 2013
Calcinosis cutis is a rare disorder resulting from the precipitation and deposition of insoluble calcium and phosphate salts (hydroxyapatite crystals) in the dermis and subcutaneous tissue. It is generally divided into four main groups on the basis of etiology and pathogenesis. Clinical presentation of cutaneous calcinosis cutis varies according to ...
Perenyi Agnes - - 2013
To assess the clinical usefulness of measurement of corpus callosum (CC) size in head ultrasound (HUS) to predict short-term neurodevelopmental (ND) outcomes in preterm infants. We hypothesised that including CC measurements in routine HUS will be an additional tool for early identification of infants at risk of adverse short-term ND ...
Pacifici Gian Maria GM Section of Pharmacology, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa 56100, Italy. - - 2013
Furosemide is the diuretic most used in newborn infants. It blocks the Na+-K+-2Cl- symporter in the thick ascending limb of the loop of Henle increasing urinary excretion of Na+ and Cl-. This article aimed to review the published data on the clinical pharmacology of furosemide in neonates to provide a ...
Wei Xufeng X Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland 21201, - - 2013
The infant Jarvik 2000 heart is a very small, hermetically sealed, intracorporeal, axial-flow ventricular assist device (VAD) designed for circulatory support in neonates and infants. The anatomic fit, short-term biocompatibility and hemodynamic performance of the device were evaluated in a neonate piglet model. The infant Jarvik 2000 heart with two ...
Abhyankar Swapna S National Library of Medicine, Bethesda, - - 2013
Knowledge about maternal history is critical for guiding certain aspects of newborn clinical care as well as for research on neonatal issues. However, often the only maternal history available in the newborn record is in the clinical notes. We are using data from the MIMIC-II database for a clinical study ...
García Evamariely - - 2013
Adrenocortical carcinoma (ACC) is a rare neoplasm in children. Most patients with ACC suffer syndromes of adrenal hormone overproduction including hypercortisolism, hyperaidosteronism or virilization. We describe the case of an infant girl who presented features of virilization associated with elevated testosterone and DHEA levels due to the presence of a ...
Hoppe Camilla C Division of Nutrition , National Food Institute, Technical University of Denmark , Mørkhøj Bygade 19, DK-2860 Søborg , - - 2013
Coeliac disease (CD) affects about 1 % of the general population. Information concerning gluten intake in the general population is scarce. In particular, variation in gluten intake during the complementary feeding period may be an independent risk factor in CD pathogenesis. We determined the intake of gluten from wheat, barley, rye ...
Davies Hr H Division of Human Nutrition, Stellenbosch - - 2013
The aim of this study was to investigate the ability of the gestational body mass index (BMI) method to screen for adverse birth outcomes and maternal morbidities. This was a substudy of a randomised controlled trial, the Philani Mentor Mothers' study. The Philani Mentor Mothers' study took place in a ...
Bekhof Jolita - - 2012
Late-onset neonatal sepsis (LOS) in preterm infants is an important cause of morbidity and mortality in preterm infants. Since presenting symptoms may be non-specific and subtle, early and correct diagnosis is challenging. We aimed to develop a nomogram based on clinical signs, to assess the likelihood of LOS in preterms ...
Tokumasu Hironobu - - 2012
BACKGROUND: Clinical chorioamnionitis and histological chorioamnionitis are important risk factors for neonatal complications and neurodevelopmental impairment in premature infants. However, it is unclear whether a diagnosis of clinical chorioamnionitis is sufficient to establish a diagnosis of histological chorioamnionitis. Here, we evaluated the predictive value of clinical chorioamnionitis in the diagnosis ...
van Thuijl Anders - - 2012
The double-blind placebo-controlled food challenge (DBPCFC) is currently the gold standard to diagnose cow's milk allergy (CMA). However, DBPCFCs are burdensome, expensive and require specialised facilities. For primary care physicians, selective and consistent referral to DBPCFC of infants suspected of CMA may be difficult. The objective of this study was ...
Schmölzer Georg M - - 2012
Tracheal intubation remains a common procedure during neonatal intensive care. Rapid confirmation of correct tube placement is important because tube malposition is associated with serious adverse outcomes. The current gold standard test to confirm tube position is a chest radiograph, however this is often delayed until after ventilation has commenced. ...
El-Khashab Mostafa - - 2012
Brain abscess in young infants is extremely rare and usually associated with a previous history of bacterial meningitis or septicemia. Here we report a cerebellar abscess mimicking brain tumor with atypical clinical and paraclinical presentations. A two-month old previously well-baby boy was referred to us with persistent vomiting, strabismus and ...
Shankaran Seetha - - 2012
This article covers the outcome of full-term infants with encephalopathy due to hypoxic-ischemia and pathophysiology of brain injury following hypoxic-ischemia. Clinical and imaging evidence for hypothermia for neuroprotection is presented. The outcome of infants with hypothermia for encephalopathy due to hypoxic-ischemia from recent trials is summarized. Facts regarding the clinical ...
Shore Richard M - - 2012
This is the continuation of a two-part review of rickets. This part emphasizes the specific pathophysiology, clinical features, pathoanatomy and radiographic findings of vitamin D deficiency rickets. Other forms of rickets, differential diagnostic considerations and the potential relationship between low levels of vitamin D metabolites and unexplained fractures in infants ...
Mussap M - - 2012
Despite a 35% decline in the mortality rate for infants aged <5 years over the past two decades, every year nearly 40% of all deaths in this age group occur in the neonatal period, defined as the first 28 days of life. New knowledge on molecular and biochemical pathways in ...
Ohishi Akira - - 2013
We report on a Filipino neonate with early onset and prolonged hyperbilirubinemia who was delivered by a vacuum extraction due to a prolonged labor. Subsequent studies revealed adrenal hemorrhage and glucose-6-phosphate dehydrogenase (G6PD) deficiency. It is likely that asphyxia and resultant hypoxia underlie the occurrence of adrenal hemorrhage and the ...
Bailey Dana D Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, - - 2013
With an ever-increasing clinical interest in vitamin D insufficiency, numerous automated immunoassays, protein binding assays, and in-house LC-MS/MS methods are being developed for the quantification of 25-hydroxyvitamin D(3) (25(OH)D(3)). Recently, LC-MS/MS methods have identified an epimeric form of 25(OH)D(3) that has been shown to contribute significantly to 25(OH)D(3) concentration, particularly ...
Nelson Karin B KB Children's Hospital National Medical Center, Washington, District of Columbia, USA. - - 2012
Neonatal encephalopathy (NE) is a major predictor of death and long-term neurologic disability, but there are few studies of antecedents of NE. To identify antecedents in a large registry of infants who had NE. This was a maternal and infant record review of 4165 singleton neonates, gestational age of ≥ ...
SÅ‚omka Artur - - 2012
Abstract Objective: To assess the relationship between parameters of iron homeostasis in infants and clinical features characterising newborns and their mothers. Methods: The goal of the present work was to determine nine iron status parameters, i.e. hepcidin, prohepcidin, soluble transferrin receptor, ferritin, total iron binding capacity, unsaturated iron binding capacity, ...
Maclean Joanna E - - 2012
OBJECTIVE: To determine the prevalence of sleep-disordered breathing (SDB) symptoms and respiratory events during sleep in infants with cleft lip and/or palate (CL/P). DESIGN: Prospective observational study. SETTING: Cleft palate clinic, tertiary care paediatric hospital, before palate surgery. PATIENTS: Consecutive newborn infants with CL/P. MAIN OUTCOME MEASURES: Demographics, clinical history, ...
Hussain Shanawaz - - 2012
The authors report a case of hyperekplexia presenting in the neonatal period resistant to clonazepam that responded subsequently to levetiracetam. Hyperekplexia is often misdiagnosed as epilepsy and can be difficult to manage with a particular concern over neonatal apnea and an increased risk of sudden infant death syndrome. The mainstay ...
Trevisanuto Daniele - - 2012
Oxygen has been widely used in neonatal resuscitation for about 300 years. In October 2010, the International Liaison Committee on Neonatal Resuscitation released new guidelines. Based on experimental studies and randomized clinical trials, the recommendations on evaluation and monitoring of oxygenation status and oxygen supplementation in the delivery room were ...
Cerbo R M - - 2012
Near infrared spectroscopy (NIRS) measures the regional tissue oxygen saturation (rSO2) of various organs and provides a reflection of the balance between tissue oxygen supply and demand. Oxymetry assessed via NIRS has been proposed as a 'standard of care' and today it is already widely used in the NICU. This ...
Amin Sachin C - - 2012
Objective: Several case reports and retrospective studies have reported a temporal association between red blood cell (RBC) transfusions and necrotizing enterocolitis (NEC). In this article, we review the clinical evidence and biological plausibility of the association between RBC transfusions and NEC. Methods: A literature search was performed using the databases ...
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