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Barnhart Kurt T KT Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: - - 2014
Well-designed and -conducted clinical trials are needed to further advance the field for reproductive medicine. However, current reporting of outcomes of trials is ambiguous and disparate. In this review it is offered that the preferred outcome for clinical trials in reproductive medicine should be live birth. Multiple births should be ...
Aydın Halil Ibrahim HI Department of Pediatrics, Gülhane Military Medical Academy, Ankara. - - 2014
The aim in this study was to determine the factors affecting leptin and soluble leptin receptor (sOB-R) levels in term small for gestational age (SGA) and appropriate for gestational age (AGA) newborns. The study group consisted of SGA (n=20) and AGA (n=20) newborns and their mothers. The leptin and sOB-R ...
Van Noolen L L Département de Biochimie, Toxicologie et Pharmacologie, Institut de Biologie et Pathologie, CHU Grenoble, Grenoble, - - 2014
Vitamin B12 deficiency can lead to serious haematological and neurological signs in infants. The reported clinical cases of vitamin B12 deficiency were found in exclusively breast-fed infants whose asymptomatic mothers were diagnosed later with pernicious anaemia. For the infants, the diagnosis required urinary methylmalonic acid quantification (grossly elevated in these ...
Finkel Richard S RS Divisions of Neurology, Nemours Children's Hospital, Orlando, - - 2014
To determine the feasibility and safety of respiratory muscle function testing in weak infants with a progressive neuromuscular disorder. Respiratory insufficiency is the major cause of morbidity and mortality in infants with spinal muscular atrophy type I (SMA-I). Tests of respiratory muscle strength, endurance, and breathing patterns can be performed ...
Benkoe Thomas M TM Department of Pediatric Surgery, Medical University of Vienna, Austria. Electronic address: - - 2014
In recent years several potential biochemical markers have been evaluated to facilitate a reliable diagnosis of necrotizing enterocolitis (NEC), but none have made progress to clinical routine. We performed a comparative assessment in premature infants to evaluate the diagnostic value of the routinely available cytokine interleukin (IL)-8, and two promising ...
Tidmarsh G F GF Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, - - 2014
Hemolytic disease in newborns can result from a number of conditions, which can place such infants at an increased risk for the development of severe hyperbilirubinemia. Because the catabolism of heme produces equimolar amounts of carbon monoxide (CO) and bilirubin, measurements of end-tidal breath CO (corrected for ambient CO) or ...
Patel Shyama D SD *Department of Pediatrics/Newborn Medicine, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10025, - - 2014
Neonatal encephalopathy resulting from HI (hypoxia-ischaemia) continues to be a significant cause of mortality and morbidity in infants and children, affecting 1-2/1000 live term births and up to 60% of pre-term births. In order to understand the pathophysiology of this insult, as well as design therapeutic interventions, it is important ...
Erfanianahmadpoor Mahmood M Anatomy Department, Mashhad Medical Branch, Islamic Azad University, Mashhad, - - 2014
To assess specific anti-cytomegalovirus (CMV) antibodies, clinical status, and demographic data in pregnant women and their infants in northeast Iran. This cross-sectional study was conducted on 225 systematic randomly selected-pregnant women and their newborns attending public hospitals in Mashhad, Iran between December 2007 and January 2008. Two specialists performed clinical ...
Geneva Ina E - - 2014
To explore the capacity of somatosensory evoked potentials (SEP) to assess maturation processes in the development of the nervous system, and the characteristics of SEP in healthy full-term infants and full-term newborns with perinatal asphyxia and their follow up until the age of 14 months. SEP were studied in 21 ...
Shemie Sam D SD Canadian Blood Services and Division of Critical Care, Montreal Children's Hospital, McGill University Health Centre, 2300 Tupper Street room C-806, Montreal, QC, H3H 1P3, Canada, - - 2014
This report summarizes the results of the first phase in the development of international guidelines for death determination, focusing on the biology of death and the dying process, developed by an invitational forum of international content experts and representatives of a number of professional societies. Precise terminology was developed in ...
Avhad Rajendra R Assistant Professor, Department of Prosthetic Dentistry, Government Dental College and Hospital, Mumbai, Maharashtra, - - 2014
A cleft lip and palate consists of fissures of the upper lip and/or palate, and is the most commonly seen orofacial anomaly that involves the middle third of the face. Early treatment of patients with a cleft lip and palate is important because of esthetic, functional, and psychological concerns. Nasoalveolar ...
Zanelli S S Department of Pediatrics, University of Virginia, Charlottesville, VA, USA. Electronic address: - - 2014
Hypoxemic events are common in sick preterm and term infants and represent the most common cause of seizures in the newborn period. Neonatal seizures often lack clinical correlates and are only recognized by electroencephalogram (EEG). The mechanisms leading from a hypoxic/ischemic insult to acute seizures in neonates remain poorly understood. ...
Falkenstein-Hagander Kathy K Department of Pediatrics, Skåne University Hospital Malmö, Lund University, Sweden; Department of Anesthesiology, Children's Hospital Boston, Boston, MA, - - 2014
To determine the prevalence of various types of viruses in infants hospitalised due to respiratory distress, compare molecular diagnostic tests and evaluate symptom severity METHODS: All 136 nasopharyngeal aspirates from infants hospitalised for respiratory distress over a nine-month period were analysed for virus type by in-house respiratory syncytial virus (RSV) ...
Meadows John Thomas JT Jr Division of Neonatology, University of Tennessee Medical Center, Knoxville, Tennessee. Electronic address: - - 2014
Rachischisis totalis is a rare open neural tube defect often associated with lethal acrania. When acrania is not present, mortality remains high and morbidity for survivors is extreme. We describe is a term newborn with in-utero diagnosed rachischisis totalis without acrania and Chiari II malformation with subsequent hydrocephalus. At birth, ...
Carcillo Joseph A JA Department of Pediatrics and Critical Care Medicine, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA. Electronic address: - - 2014
This is a synopsis of the term newborn and infant portion of the 2007 document (Brierley et al., Crit Care Med 2009;37(2):666-88) which examined and graded new studies performed to test the utility and efficacy of the 2002 recommendations. This 2007 document examined and graded relevant new treatment and outcome ...
Thorley Virginia - - 2014
In 20th century Australia, free well-baby clinics were run by maternal and child health nurses, although the funding and organisational structure varied from state to state. It was assumed that women who attended followed the advice assiduously; yet attendance did not necessarily equate to practice. In Queensland, the state government's ...
Canty Kristi M KM From the Section of Dermatology, Children's Mercy Hospitals and Clinics, and the Department of Radiology, University of Missouri-Kansas City School of Medicine, Kansas City, - - 2014
The objectives of the study were to determine the rate of hepatic hemangiomas in infants with cutaneous infantile hemangiomas that were screened by abdominal ultrasound; identify morphological subtypes and number of cutaneous infantile hemangiomas that are likely to suggest the presence of hepatic hemangiomas; and identify clinical history, physical findings, ...
Liu Jing J Department of Neonatology, NICU, Bayi Children's Hospital Affiliated to Beijing Military General Hospital, Beijing, - - 2014
Respiratory distress syndrome (RDS) is a common critical disease in term neonates, but reasons for the occurrence of RDS remains unclear. This study aimed to investigate the cause of RDS in full-term neonates by a retrospective case-control study. Case-control study. Among the patients admitted to Bayi Children's Hospital between January ...
Nimbalkar Somashekhar Marutirao SM Professor, Department of Paediatrics, Pramukhswami Medical College , Karamsad, Gujarat, India - - 2014
Tracheal Agenesis (TA) presents with respiratory distress at birth. Diagnosis requires recognition of clinical signs in newborns like failure of endotracheal intubation, respiratory distress with absent air entry over both side of chest and inaudible cry. We describe a TA Floyd Type I with a Tracheo-Oesophageal Fistula (TOF) without other ...
Torkildsen Oivind O The Norwegian Multiple Sclerosis Competence Centre, Department of Neurology, Haukeland University Hospital Bergen, Norway ; Kristian Gerhard Jebsen Centre for MS-Research, Department of Clinical Medicine, University of Bergen Bergen, - - 2014
A month of birth effect on multiple sclerosis (MS) risk has been reported from different countries. Recent critics have suggested that this finding is caused by confounding and that adequately adjusting for year and place of birth would markedly reduce this effect. All inhabitants in Norway are registered in the ...
Richter Linda L Human Sciences Research Council, Durban, KwaZulu-Natal, South - - 2014
Throughout Africa, Peer Mentors who are women living with HIV (WLH) are supporting pregnant WLH at antenatal and primary healthcare clinics (McColl in BMJ 344:e1590, 2012). We evaluate a program using this intervention strategy at 1.5 months post-birth. In a cluster randomized controlled trial in KwaZulu-Natal, South Africa, eight clinics were ...
Zhou Wei-Qin WQ Department of Pediatrics, BaYi Children's Hospital Affiliated to the Clinical Medical College of the General Hospital of Beijing Military Region, Southern Medical University, Beijing, - - 2014
Information about clinical outcomes of very preterm (VPT) infants in tertiary neonatal intensive care unit (NICU) setting is scant in China. This study aimed to investigate the mortality and morbidity of VPT infants admitted to BaYi Children's Hospital, which serves as a NICU referral center for the city of Beijing, ...
Rotheram-Borus Mary Jane MJ Global Center for Children and Families, University of California, Los Angeles, California, United States of - - 2014
We evaluate the effect of clinic-based support by HIV-positive Peer Mentors, in addition to standard clinic care, on maternal and infant well-being among Women Living with HIV (WLH) from pregnancy through the infant's first year of life. In a cluster randomized controlled trial in KwaZulu-Natal, South Africa, eight clinics were ...
Tsai Ming-Horng MH Division of Neonatology and Pediatric Hematology/Oncology, Department of Pediatrics, Chang Gung Memorial Hospital, Yunlin, Taiwan ; College of Medicine, Chang Gung University, Taoyuan, Taiwan ; Chang Gung University of Science and Technology, Chiayi, - - 2014
Polymicrobial bloodstream infections (PBSIs) have been associated with complex underlying medical conditions and a high incidence of specific microorganisms in several settings, but the relevant data are scarce in neonates. Positive blood cultures from January 2004 to December 2011 in the neonatal intensive care unit (NICU) of Chang Gung Memorial ...
Sullivan Brynne A BA Department of Pediatrics, University of Virginia Health System, Charlottesville, - - 2014
To identify clinical conditions associated with a large increase (spike) in the heart rate characteristics index in very low birth weight (VLBW) infants. Retrospective medical record review within a day of all large heart rate characteristics index spikes (increase of ≥3 from the previous 5-day average) in VLBW infants at ...
Maastrup Ragnhild R Knowledge Centre for Breastfeeding Infants with Special Needs at Department of Neonatology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark ; Department of Health Sciences, Faculty of Medicine, Lund University, Lund, Sweden ; Danish National Panel of Experts on Breastfeeding Infants with Special - - 2014
Evidence-based knowledge of how to guide the mothers of preterm infants in breastfeeding establishment is contradictive or sparse. The aim was to investigate the associations between pre-specified clinical practices for facilitating breastfeeding, and exclusive breastfeeding at discharge as well as adequate duration thereof. A prospective survey based on questionnaires was ...
Ji Jun J State Key Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Zhejiang University, Hangzhou, Zhejiang, China ; Department of Surgery, Stanford University, Stanford, California, United States of - - 2014
Necrotizing enterocolitis (NEC) is a major source of neonatal morbidity and mortality. Since there is no specific diagnostic test or risk of progression model available for NEC, the diagnosis and outcome prediction of NEC is made on clinical grounds. The objective in this study was to develop and validate new ...
Yilmaz Osman O Department of Pediatric Cardiology, District Training and Research Hospital, Erzurum, 25070, - - 2014
Superior vena cava syndrome (SVCS) is rare in infants. Non-Hodgkin lymphoma is the most common cause of SVCS in children. Swelling in the face and neck are the most common clinical symptoms associated with this syndrome. However, these clinical findings are also observed in allergic diseases, which therefore often leads ...
Markham Kara B KB Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, The Ohio State University, Columbus, - - 2014
To evaluate whether progestin prophylaxis influenced the odds of recurrent spontaneous preterm birth among pregnant women with a previous preterm birth. A retrospective cohort study was performed evaluating outcomes of pregnant women with one or more previous preterm births who received prenatal care in a single academic prematurity clinic. Care ...
Poddighe Dimitri D Department of Pediatrics, Ospedale di Circolo di Melegnano, Vizzolo Predabissi, - - 2014
Unconjugated hyperbilirubinaemia is a common finding in newborns. When it is exaggerated, it is usually investigated in order to exclude several diseases, such as newborn's haemolytic diseases, infections or hypothyroidism. Breast milk jaundice is a form of neonatal jaundice related to breast feeding and it is not usually associated with ...
García-Muñoz Rodrigo Fermín F Complejo Hospitalario Universitario Insular Materno-Infantil de Las Palmas, Las Palmas de Gran Canaria, - - 2014
Background: Chorioamnionitis is a recognized risk factor of preterm delivery; however, controversy still persists concerning the relationship between maternal inflammation and neonatal morbidity and mortality. Objective: To determine the incidence of clinical chorioamnionitis and its relationship to morbidity and mortality among very-low-birth-weight (VLBW) infants. Methods: This was a retrospective analysis ...
Chiao Sunny S Department of Anesthesiology, University of Virginia, Charlottesville, VA 22908, USA. - - 2014
The use of volatile anesthetics, a group of general anesthetics, is an exceedingly common practice. These anesthetics may have neuroprotective effects. Over the last decade, anesthetic induced neurotoxicity in pediatric populations has gained a certain notoriety based on pre-clinical cell and animal studies demonstrating that general anesthetics may induce neurotoxicity, ...
Liao Steve M - - 2014
The neurodevelopmental outcome of at-risk infants in the neonatal intensive care unit (NICU) is concerning despite steady improvement in the survival rate of these infants. Our current management is often complicated by delayed realization of cerebral deficits due to late manifestation and lack of effective screening tools and neuroimaging/monitoring techniques ...
Cuna Alain A Department of Pediatrics, Winthrop University Hospital , Mineola, NY , - - 2014
Although histologic chorioamnionitis (HCA) is known to be associated with poor outcomes in preterm infants, its clinical significance among term infants is not clearly known. To investigate the utility of HCA in determining early onset clinical sepsis (EOCS) among term newborns. The incidence of HCA and EOCS in term infants ...
Kemfang Ngowa Jean Dupont JD 0000-0003-2404-0595 Department of Obstetrics and Gynecology, Faculty of Medicine and Biomedical Sciences, Yaounde General Hospital, University of Yaounde I, P.O. Box 5408, Yaounde, - - 2014
Objective. To establish the percentile charts of birth weights for gestational age and sex within the Cameroonian population. Methods. A review of medical records of infants born between January 2007 and December 2011 at the maternities of two hospitals in Cameroon, Central Africa. Multiple pregnancies, births of HIV infected women, ...
Nowicka Agnieszka - - 2014
Evaluation of nasal CPAP (Infant Flow) as a ventilatory support, applied at birth in spontaneously breathing, extremely low birth weight newborns (ELBW). Retrospective analysis of the clinical course of respiratory distress syndrome (RDS) in 97 ELBW, who needed ventilatory support. In all patients the noninvasive ventilatory support was introduced within ...
Trumpff Caroline C Unit of Public Health and Surveillance, Scientific Institute of Public Health, Brussels, Belgium ; Faculté des Sciences Psychologiques et de l'Education, Université Libre de Bruxelles, Brussels, - - 2014
Several European countries, including Belgium, still suffer from mild iodine deficiency. Thyroid stimulating hormone (TSH) concentration in whole blood measured at birth has been proposed as an indicator of maternal iodine status during the last trimester of pregnancy. It has been shown that mild iodine deficiency during pregnancy may affect ...
Fernandes Ricardo M RM Department of Pediatrics, Santa Maria Hospital, Lisbon Academic Medical Centre, Portugal2Clinical Pharmacology Unit, Instituto de Medicina Molecular, University of Lisbon, - - 2014
Are glucocorticoids, alone or combined with bronchodilators, associated with reduced admission rates, length of stay, or improvements in clinical severity scores without increased adverse effects in infants and young children with acute viral bronchiolitis? There is no consistent clinically relevant association of single therapy with systemic or inhaled glucocorticoids and ...
Czech-Kowalska Justyna J Department of Neonatology and Neonatal Intensive Care, The Children's Memorial Health Institute, Warsaw, - - 2014
The optimal vitamin D intake for nursing women is controversial. Deterioration, at least in bone mass, is reported during lactation. This study evaluated whether vitamin D supplementation during lactation enhances the maternal and infant's vitamin D status, bone mass and body composition. After term delivery, 174 healthy mothers were randomized ...
Wang Keyi K Department of Central Laboratory, Hangzhou First People's Hospital, No. 261 Huansha Road, Hangzhou, Zhejiang 310002, - - 2014
Objectives. To evaluate the predictive characteristics of KL-6 and CC16 for bronchopulmonary dysplasia (BPD) in preterm infants, either independently or in combination. Study Design. This prospective cohort study was performed from 2011 to 2013 with preterm neonates of gestational age ≤32 weeks and birth weight ≤1500 g. Serum KL-6 and CC16 ...
Menezes Fernando Gatti FG Serviço de Controle de Infecção Hospitalar Hospital Albert Einstein São PauloSP Brazil Serviço de Controle de Infecção Hospitalar, Hospital Albert Einstein, São Paulo, SP, - - 2014
Ochrobactrum anthropi infection in newborn patients is rare, and the treatment is challenging because of its widespread and unpredictable resistance to antimicrobial agents and discrepancies between in vitro susceptibility and in vivo efficacy. We report the clinical and microbiological characteristics of Ochrobactrum anthropi bacteremia in a preterm patient.
Frostegård Anna G AG Unit of Immunology and Chronic Disease, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, - - 2014
To determine levels of athero-protective IgM antibodies against phosphorylcholine in mothers and term-born normal or low birth weight infants. Twenty three mother-infant pairs were studied, of whom 16 infants were within the normal weight range for gestational age (NGA; 3652[504] g) and 7 were small for gestational age (SGA; birth ...
Lombard Martani J MJ Centre of Excellence for Nutrition (CEN), North-West University, Potchefstroom, South - - 2014
Introduction: Infant and young child (IYC) growth impairment remains a public health problem in Africa partly because infants are exposed to staple foods (contaminated with mycotoxins) at an early age. Understanding the role of mycotoxins in IYC growth is vital, and this paper systematically reviews the available knowledge. Methods: Studies ...
Rotheram-Borus Mary Jane MJ Department of Psychiatry and Biobehavioral Medicine, Semel Institute, University of California Los Angeles, Los Angeles, California, United States of - - 2014
Interventions are needed to reduce poor perinatal health. We trained community health workers (CHWs) as home visitors to address maternal/infant risks. In a cluster randomised controlled trial in Cape Town townships, neighbourhoods were randomised within matched pairs to 1) the control, healthcare at clinics (n = 12 neighbourhoods; n = 594 women), or 2) ...
Huseynova Saadat S Department of Neonatology, Azerbaijan Medical University, Baku, - - 2014
Perinatal hypoxia results in neuronal and endothelial cell damage. The main purpose of this study was to investigate the correlation of soluble intercellular adhesion molecule 1 (sICAM-1) expression and peripheral blood changes in perinatal asphyxia with neuronal injury markers in low birth weight (LBW) neonates. We compared the concentrations of ...
Wood Stephen S University of Calgary. - - 2014
To evaluate a possible association between neighbourhood socio-economic status and spontaneous premature birth in Alberta births. The study design was a retrospective cohort of all births in Alberta for the years 2001 and 2006. The primary outcome was spontaneous preterm birth at <37 weeks gestation. Neighbourhood socio-economic status was measured ...
Nikolarakou Athina A 0000-0002-4685-0946 Cliniques Universitaires Saint-Luc, Service de Pédiatrie, Avenue Hippocrate 10, 1200 Brussels, - - 2014
Primary arthritis of chondrosternal joint is very rare and occurs in infants less than 18 months of age. Presentation is most often subacute but may be acute. Child presents with a parasternal mass with history of fever and/or local signs of infection. Clinical symptoms vary from a painless noninflammatory to ...
Sobze Martin Sanou MS Department of Biomedical Sciences, Faculty of Sciences, University of Dschang, Dschang, - - 2014
Poor infant feeding practices are common in Africa, resulting in physical and intellectual developmental impairments. Good feeding practices are crucial, especially in the first year of growth. HIV/AIDS has worsened the clinical and nutritional status of both mothers and their children, exacerbating high rates of malnutrition. The aim of this ...
Savino Francesco F Department of Paediatrics, University of Turin, Regina Margherita Children's Hospital, Turin, - - 2014
Reports on leptin concentrations in pediatric populations lack reference values for infants in the first months of life. Our study was conducted on healthy full-term infants between 2002 and 2012 to determine serum leptin reference values in subjects less than 18 months old. Routine outpatient blood tests for serum leptin ...
Doll Elizabeth E Division of Pediatric Neurology, School of Medicine, University of Utah , Salt Lake City, UT , - - 2014
Objective: Chronic neurological deficits are a significant complication of preterm birth. Magnesium supplementation has been suggested to have neuroprotective function in the developing brain. Our objective was to determine whether higher neonatal serum magnesium levels were associated with better long-term neurodevelopmental outcomes in very-low birth weight infants. Study Design: A ...
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