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Dierig Alexa A 1 University Children's Hospital Basel, Division of Pediatric Infectious Diseases 2 Division of Infection Diagnostics, Department Biomedicine (Haus Petersplatz), University of Basel 3 University of Basel, - - 2014
Short courses of antibiotic therapy are recommended for treatment of pertussis. We report two young unvaccinated infants with persistently positive B. pertussis by PCR from nasopharyngeal swabs despite 7 days of clarithromycin (15 mg/kg/d) therapy. In one patient, quantitative PCR was 7.02 (log GEq/ml) at onset of treatment, 6.26 at end ...
Lake Eileen T ET Center for Health Outcomes and Policy Research, School of Nursing, Department of Sociology, Leonard Davis Institute of Health Economics, University of Pennsylvania, 302 Claire M. Fagin Hall, Philadelphia, PA - - 2014
To determine if hospital-level disparities in very low birth weight (VLBW) infant outcomes are explained by poorer hospital nursing characteristics. Nurse survey and VLBW infant registry data. Retrospective study of 8,252 VLBW infants in 98 Vermont Oxford Network hospital neonatal intensive care units (NICUs) nationally. NICUs were classified into three ...
Lee Henry C HC Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University, Palo Alto, - - 2014
Objective This study aims to characterize population risks for diagnosis, medical treatment, and surgical ligation of patent ductus arteriosus (PDA) in very low-birth-weight infants. Study Design Maternal and neonatal data were collected in 40 hospitals in California during 2011 for infants with birth weight ≤ 1,500 g without any congenital malformation, with a diagnosis of ...
Juster-Reicher A A Department of Neonatology, Kaplan Medical Center, Rehovot, Hebrew University, Jerusalem, - - 2014
Abstract Aim: To investigate the correlation between transcutaneous bilirubinometry (TcB) and total serum bilirubin (TsB) in jaundiced infants before and after, but not during phototherapy. Methods: This study prospectively investigated the correlation between TcB and TsB in term and near term infants before and after phototherapy. Results: 673 pairs of ...
Hedstrom Anna - - 2014
Ninety-six percent of the world's 3 million neonatal deaths occur in developing countries where the majority of births occur outside of a facility. Community-based approaches to the identification and management of neonatal illness have reduced neonatal mortality over the last decade. To further expand life-saving services, improvements in access to ...
Weiner J J Division of Neonatology, Children's Mercy Hospitals and Clinics, University of Missouri-Kansas City, School of Medicine, Kansas, MO, - - 2014
Objective:To determine the influence of physiological status and diagnosis at the time of death on end-of-life care.Study Design:Retrospective descriptive study in a regional referral level IV neonatal intensive care unit (NICU) of infants who died from 1 January 1999 to 31 December 2008. Infants were categorized based on diagnosis (very ...
Drozd-Lipińska Alicja A Department of Anthropology,Nicolaus Copernicus University in - - 2014
Summary Analyses of historical or modern populations indicate a strong relationship between mortality level and standard of living, measured, among other factors, by degree of urbanization. The aim of this study was to assess mortality rates in children of up to 5 years of age in two populations living under ...
Ping Li L LL Division of Neonatology, Children's Hospital, Fudan University, Shanghai, - - 2014
Background: Neonatal necrotizing enterocolitis (NEC) is associated with an increased incidence of poor neurodevelopment. The knowledge of underlying neurophysiology is very limited, and the influence of NEC on the preterm brainstem is very poorly understood. Objective: To assess the effect of NEC on the immature auditory brainstem by excluding any ...
Hyttel-Sorensen Simon S Department of Neonatology, National University Hospital, Rigshospitalet, Blegdamsvej 9, Copenhagen, DK-2100, - - 2014
Previously the NIRS oximeter OxyPrem was calibrated by comparison to the INVOS in a blood-lipid phantom. The aim of the present study was to test this calibration clinically. During vasculur occlusions in 10 adults and after birth in 25 term infants the relationship was OxyPrem = 1.24 x INVOS - ...
Chambers Georgina M GM National Perinatal Epidemiology and Statistics Unit, School of Women's and Children's Health, The University of New South Wales, Sydney, - - 2014
The unprecedented increase in multiple births during the past 3 decades is a major public health concern and parallels the uptake of medically assisted conception. The economic implications of such births are not well understood. To conduct a comprehensive economic and health services assessment of the frequency, duration, and cost ...
Zhang Shulian S Department of Neonatology, Children's Hospital of Fudan University, Shanghai, - - 2014
To investigate plasma ghrelin and obestatin levels, and ghrelin/obestatin prepropeptide gene polymorphisms, in sequentially enrolled small for gestational age (SGA) infants. Neonates were sequentially enrolled into this study and were then subdivided into different groups, according to different study aims and availability of study materials. Consequently, plasma ghrelin and obestatin ...
Fettah Nurdan Dinlen ND Neonatal Intensive Care Unit, Dr. Sami Ulus Maternity and Children Research and Training Hospital, Ankara, - - 2014
Objective The objective of this study was to investigate the relationship between cord blood 25-hydroxyvitamin D (25(OH)D) levels and respiratory distress syndrome (RDS) development in preterm infants. Study Design Between January 2012 and January 2013, 81 preterm infants, gestational age below 32 weeks, were prospectively enrolled into the study. Cord bloods of ...
Fukuda Misao M M&K Health Institute, Ako, Hyogo, Japan. Electronic address: - - 2014
To evaluate whether climate change is associated with male:female ratios (sex ratios) of fetal deaths and births in Japan. A population-based cohort study. Not applicable. Newborn infants and fetuses spontaneously aborted after 12 weeks of gestation. None. Yearly sex ratios of fetal deaths and newborn infants and monthly fetal death rates ...
Moffett Brady S BS 1Department of Pharmacy,Texas Children's Hospital,Houston,Texas,United States of - - 2014
Introduction: Digoxin or propranolol are used as first-line enteral agents for treatment of infant supraventricular tachycardia. We used a large national database to determine whether enteral digoxin or propranolol was more effciacious as first-line infant supraventricular tachycardia therapy. Materials and Methods: The Pediatric Health Information System database was queried over ...
Langan Martin Julie - - 2014
BackgroundSocioeconomic status has important associations with disease-specific mortality in the general population. Although individuals with Severe Mental Illnesses (SMI) experience significant premature mortality, the relationship between socioeconomic status and mortality in this group remains under investigated. We aimed to assess the impact of socioeconomic status on rate and cause of ...
García-Bournissen Facundo F Parasitology and Chagas Service, Buenos Aires Children's Hospital "Dr Ricardo Gutierrez", Buenos Aires, - - 2014
Benznidazole (BNZ) is safe and effective for the treatment of paediatric Chagas disease. Treatment of adults is also effective in many cases, but discouraged in breastfeeding women because no information on BNZ transfer into breast milk is available. We aimed to evaluate the degree of BNZ transfer into breast milk ...
Kocova Mirjana M Department of Endocrinology and Genetics, University Clinic for Children's Diseases, Vodnjanska 17, Skopje, Macedonia, - - 2014
To evaluate the thyroid screening program and to estimate the prevalence of congenital hypothyroidism (CH) among newborns in the Republic of Macedonia, we measured thyroid-stimulating hormone (TSH) levels in dried blood spot specimens using the DELFIA fluoroimmunoassay, over a period of 12 years. The TSH cutoff level was 10 mU/L blood. A ...
Troisi J J Dipartimento di ostetricia e ginecologia, Università degli studi di Salerno, Italy. Electronic address: - - 2014
Bisphenol A (BPA) is a weakly estrogenic compound that has been detected in a wide variety of food products and biological matrices (saliva, blood, urine, etc). Despite the potential risk of human exposure to BPA, little information exists concerning maternal and fetal exposure to BPA during pregnancy. The aim of ...
Puckering Christine - - 2014
Effective early intervention to prevent oppositional/conduct disorders requires early identification of children at risk. Patterns of parent-child interaction may predict oppositional/conduct disorders but large community-based prospective studies are needed to evaluate this possibility. We sought to examine whether the Mellow Parenting Observational System (MPOS) used to assess parent-infant interactions at ...
Tagliaferro T T Division of Neonatology, Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY, - - 2014
Objective:To determine whether early radiologic evidence of severe respiratory distress syndrome (RDS) is predictive of nasal continuous positive airway pressure (CPAP) failure in extremely low birth weight (ELBW) infants during the first 72 h of age.Study design:Retrospective analysis of 235 consecutively inborn ELBW infants who received initial support with CPAP. CPAP ...
Darfour-Oduro Sandra Asantewaa SA 1 Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign , Urbana, - - 2014
Abstract A low breastfeeding rate has been a consistent maternal and child health problem in the United States, especially for low-income families. Understanding mothers' social environment and overall well-being is important in determining how mothers will take care of themselves and their infants during the postnatal period in relation to ...
Xinghan Kristy Fu KF 1Khoo Teck Puat - National University Children's Medical Institute, National University Health System, Singapore 2Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, - - 2014
The management of patients with IL-7Rα deficient, T-B+NK+ severe combined immunodeficiency (SCID) is a challenge in absence of adequate diagnostic and treatment modalities. An infant diagnosed as SCID at 6 months of age, who received only supportive treatment is described. We present a different perspective of SCID that is managed ...
Nelson Suchitra S Department of Community Dentistry, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, - - 2014
This longitudinal study of 194 very-low birthweight (VLBW) and 184 normal birthweight (NBW) infants hypothesized that the causal pathway between birth group (VLBW or NBW) and mutans streptococci (MS) acquisition (presence) at 18-20 months is mediated by biological, behavioral, and caregiver MS levels. Biological (number of teeth at 8 and 18-20 months ...
Hakan Nilay N Division of Neonatology, Department of Pediatrics, Dr. Sami Ulus Maternity and Children Training and Research Hospital, Ankara, - - 2014
Abstract Objective: The aim of present study was to evaluate the indications and the complications associated with neonatal exchange transfusion (ET) performed for hyperbilirubinemia. Methods: This study included overall 306 neonates who underwent ET between 2005 and 2012. The demographic characteristics of patients, causes of jaundice and adverse events occurred ...
Topçu Hasan Onur HO Department of Obstetrics and Gynecology, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, - - 2014
The purpose of this study was to establish a fetal birth weight curve for gestational age for patients who presented to our tertiary referral hospital. The curve can be used for epidemiological analysis and also to develop Turkey's first national nomogram. A total of 68,255 live singleton pregnancies delivered during ...
Al-Saleh Iman I Biological & Medical Research Department, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia. Electronic address: - - 2014
To our knowledge, this study may be the first to examine the antagonistic role of selenium (Se) on oxidative stress induced by cadmium (Cd) and its impact on birth measures. Cd and Se levels were measured in umbilical-cord blood and the placentas of a subsample of 250 healthy mothers who ...
Moreno-Solís Gloria G Reina Sofía Children's Hospital, Avda Menéndez Pidal S/N, 14004, Córdoba, Spain, - - 2014
This cross-sectional study was performed to examine the prevalence of hypovitaminosis D in infants with acute bronchiolitis compared with control subjects and to evaluate the relationship between serum 25-hydroxyvitamin D (25(OH) D) and the severity of bronchiolitis. Serum 25(OH) D levels were measured by radioimmunoassay in 48 infants with acute ...
Hou Chuan C The Smith-Kettlewell Eye Research Institute, 2318 Fillmore St., San Francisco, CA, 94115, United - - 2014
Purpose. High concentrations of unconjugated bilirubin are neurotoxic and cause brain damage in newborn infants. The exact level of bilirubin that may be neurotoxic in a given infant is, however, unknown. The aim of this study was to use a quantitative measure of neural activity, the swept parameter Visual Evoked ...
Lorch Scott A SA Department of Pediatrics, The Children's Hospital of Philadelphia and Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pa; Center for Outcomes Research, The Children's Hospital of Philadelphia, Philadelphia, Pa; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pa. Electronic address: - - 2014
To examine the viability of a hospital readmission quality metric for infants requiring neonatal intensive care. Two cohorts were constructed. First, a cohort was constructed from infants born in California from 1995 to 2009 at 23 to 34 weeks' gestation, using birth certificates linked to maternal and infant inpatient records ...
Hendaus Mohamed A MA Department of Pediatrics, General Pediatrics Section, Hamad Medical Corporation, Doha, Qatar. Electronic address: - - 2014
To determine the risk of acquiring acute respiratory syncytial virus (RSV) bronchiolitis in infants and children delivered by the mode of cesarean section (C-section). A retrospective and descriptive study was conducted at Hamad Medical Corporation. Patients with ages 0 to 36 months hospitalized with acute bronchiolitis were included in the ...
Alkharfy Turki M TM Department of Pediatrics, College of Medicinal and King Khalid University Hospital, King Saud University, Riyadh, Saudi - - 2014
Background/Aim: Development of hepatic dysfunction is a well-recognized complication of total parenteral nutrition in preterm infants. Previous studies reported the incidence of total parenteral nutrition-associated cholestasis and described possible contributing factors to its pathogenesis, but little is done trying to determine its possible predictive risk factors. The aims of this ...
Matic Maja M Department Clinical Chemistry, Erasmus MC - University Medical Center Rotterdam, The - - 2014
Assess association between UGT2B7 polymorphism -900G>A (rs7438135, also known as -842G>A) with morphine kinetics in preterm newborns undergoing mechanical ventilation. Thirty-four infants were enrolled in a randomized clinical trial and allocated to rapid sequence intubation with remifentanil (1 µg/kg) or morphine (0.3 mg/kg). The latter group was included in our ...
Faverey Liesbeth Claire LC Free University of Brussels, Universitair Ziekenhuis Brussel, Brussels, - - 2014
A 4-week-old infant presented with a coagulation disorder resulting from a vitamin K deficiency. The vitamin K deficiency was caused by neonatal cholestasis due to biliary atresia. Jaundice, hepatomegaly and pale stools are the predominant presenting symptoms of biliary atresia, none of which were recognized in our patient before admission. ...
Costa Daniel F G DF Department of Surgery, Division of Pediatric Urology, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, - - 2014
Estimating bladder capacity is an important component in the evaluation of many urological disorders. For estimates to be of clinical value, precise reference ranges are needed. While accepted reference ranges have been established in adults and older children, none have been validated in infants. We endeavour to determine the normal ...
Demirel Soner S Division of Pediatric Allergy and Clinical Immunology, Faculty of Medicine, Ondokuz Mayis University, Samsun, - - 2014
Vitamin D (VitD) and its metabolites play important roles in the regulation of the respiratory and immune systems. The aim of this study was to examine serum 25(OH) vitamin D [25(OH)D] levels and VitD deficiency on the development of wheezing and clinical features. This study was a prospective cross-sectional survey ...
Charafeddine Lama - - 2014
Accurate measurement of body temperature is critical for the assessment of a newborn's general well-being. In nursery settings, the gold standard rectal thermometry has been replaced by the axillary method. However, evidence pertaining to the agreement between axillary and rectal thermometry in the newborn is controversial. In this cross-sectional study, ...
Gal S S Department of Pediatrics, Bnai Zion Medical Center, The B&R Rappaport Faculty of Medicine, Technion, 47 Golomb Street, Haifa, 31048, Israel, - - 2014
Our objective was to assess within a feasibility study the correlation and agreement of transcutaneous carbon dioxide (PtcCO2) monitoring with venous carbon dioxide (PvCO2) in infants with bronchiolitis in the emergency room (ER) and pediatric department. Sixty infants (aged 3.6 ± 3.3 months) admitted to our ER with bronchiolitis were included. PtcCO2 measurements ...
Velasco Roberto R Pediatrics Department, Rio Hortega University Hospital, Valladolid, - - 2014
There is limited evidence about the diagnostic value of urine dipsticks in young febrile infants. The aim of this study was to determine whether urine dipsticks would identify positive urine cultures in febrile infants of less than 90-days-of-age. This study was a sub-analysis of a prospective multi-centre study developed in ...
Kheddache Yasmina Y Department of Electrical Engineering, École de Technologie Supérieure, Montréal Quebec, Canada. Electronic address: - - 2014
A new approach to the automatic quantification of the acoustic parameters of the cries of healthy newborns and newborns with pathologies is presented. The purpose of the present study was to examine the relationship between acoustic parameters and pathologies of interest to characterize healthy and pathologic cries of newborns. Using ...
Suaini Noor H A NH Murdoch Childrens Research Institute, Parkville, Victoria, - - 2014
To investigate the relationship between genetic and environmental exposure and vitamin D status at age one, stratified by ethnicityThis study included56312-month-old infants in the HealthNuts population-based study. DNA from participants' blood samples was genotyped using SequenomMassARRAY MALDI-TOF system on 28 single nucleotide polymorphisms (SNPs) in six genes. Using logistic regression, ...
González-González Nieves L NL Departamento de Obstetricia y Ginecología, Hospital Universitario de Canarias, y, La Laguna, - - 2014
Objective: To determine whether the use of customized curves (CC) allows better detection of large- (LGA) or small-for-gestational age (SGA) infants at risk of adverse perinatal morbidity than non-CC in women with diabetes mellitus (DM). Material and Methods: A model of CC was applied to all infants of diabetic mothers ...
Bastek Jamie A JA Maternal and Child Health Research Program, Department of Obstetrics & Gynecology, Center for Research on Reproduction and Women's Health, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. Electronic address: - - 2014
To examine whether variation in neighborhood context is associated with preterm birth outcomes and gestational age at delivery in Philadelphia, and to determine whether these associations might persist when considering relevant individual-level variables. We analyzed individual-level data collected for a prospective cohort study of singleton pregnancies with preterm labor. We ...
Can Emrah E * Edirne State Hospital, Neonatal Intensive Care Unit , Edirne , - - 2014
Objective: To evaluate the prevalence of auditory neuropathy (AN) in late preterms treated with phototherapy for hyperbilirubinemia. Design: Prospective observational study comprising late preterms treated with phototherapy for hyperbilirubinemia. Newborns were screened with combined transient-evoked otoacoustic emissions (TEOAEs) / automated auditory brainstem responses (AABR). Infants who failed screening underwent diagnostic ...
Clarke Diana F DF 1Section of Pediatric Infectious Diseases, Boston Medical Center, Boston, Massachusetts; 2Division of Clinical Pharmacology, University of Alabama at Birmingham, Birmingham, Alabama; 3Merck Research Laboratories, Whitehouse Station, New Jersey; 4Pediatric Infectious Diseases, David Geffen School of Medicine at University of California at Los Angeles, Los Angeles, California; 5Department of Pediatrics, University of California, San Diego and Rady Children's Hospital San Diego, La Jolla, California; 6Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland; 7Division of AIDS, National Institute of Health, Bethesda, Maryland; 8Merck Research Laboratories, North Wales, Pennsylvania; 9Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland; 10Statistical and Data Analysis Center, Harvard School of Public Health, Boston, Massachusetts; 11Department of Pediatrics, Boston University School of Medicine, Boston, - - 2014
IMPAACT P1097 was a multicenter trial to determine washout pharmacokinetics and safety of in utero/intrapartum exposure to raltegravir in infants born to HIV-infected pregnant women receiving raltegravir-based antiretroviral therapy. Twenty-two mother-infant pairs were enrolled; evaluable pharmacokinetic data was available from 19 mother-infant pairs. Raltegravir readily crossed the placenta, with median ...
Schnadower David D From the *Pediatric Emergency Medicine, Washington University School of Medicine, St. Louis, MO; †Pediatric Emergency Medicine, Morgan Stanley Children's Hospital, Columbia University College of Physicians and Surgeons, New York, NY; ‡Emergency Medicine and Pediatrics, University of California, Davis School of Medicine, Sacramento, CA; §Pediatric Emergency Medicine, Texas Children's Hospital, Baylor College of Medicine, Houston, TX; ∥Paediatric Emergency Medicine and Gastroenterology, Alberta Children's Hospital, Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada; ¶Pediatric Emergency Medicine, Children's National Medical Center, George Washington University School of Medicine, Washington, DC; #Department of Biostatistics, Washington University School of Medicine, St. Louis, - - 2014
Controversy exists regarding the disposition of young febrile infants who present to emergency departments (EDs) with urinary tract infections (UTIs). In a large multicenter cohort of such patients, we aimed to determine the variation in patient disposition and clinical factors independently associated with outpatient management. Secondary analysis of a retrospective ...
Ozyurt Abdullah A Departments of Pediatric Cardiology, Erciyes University Faculty of Medicine, Kayseri, - - 2014
Palivizumab prophylaxis for RSV has been consistently reported to reduce the risk of hospital admissions related to RSV infection in children with symptomatic cardiac disease. This study was designed to investigate the efficacy of palivizumab prophylaxis among infants with congenital heart disease (CHD) in Turkey. A total of 91 infants ...
Guynes Anthony A 1University of Washington School of Medicine, Seattle, Washington USA, BS 2Puget Sound Blood Center and Department of Laboratory Medicine, University of Washington, Seattle, Washington USA 3Cardiothoracic Surgery, Seattle Children's Hospital and University of Washington School of Medicine, Seattle, Washington USA 4Transfusion Services, Seattle Children's Hospital, Seattle, WA USA 5Pediatric Cardiology, Seattle Children's Hospital and University of Washington School of Medicine, Seattle Washington - - 2014
ABO sensitization is a barrier to ABO-incompatible heart transplantation in infants. We investigate the development of ABO antibodies in infants with and without mechanical circulatory support (MCS) during their waiting period. Although the proportion of patients with antibodies was similar between the groups, the median age at antibody detection was ...
Restrepo-Mesa Sandra L SL Human Nutrition and Food Research Group, School of Nutrition and Dietetics, University of Antioquia, Carrera 75 N° 65-87, Bloque 44 of 109, Medellín, Colombia, - - 2014
Birth weight is a high impact factor in populations with high rates of immigration. This study establishes differences in birth weight (BW) and related factors among full-term newborn (NB) infants born to native and immigrant women living in Spain during 2007-2008. All NBs from Spanish mothers and mothers from the ...
Bernhard Wolfgang W Department of Neonatology, Faculty of Medicine, Eberhard-Karls-University, Calwer Straße 7, 72076, Tūbingen, Germany, - - 2014
Choline is essential to human development, particularly of the brain in the form of phosphatidylcholine, sphingomyelin and acetylcholine, for bile and lipoprotein formation, and as a methyl group donator. Choline is actively transported into the fetus, and maternal supply correlates with cognitive outcome. Interruption of placental supply may therefore impair ...
Hirsch Harry J HJ Neuropediatric Unit, Shaare Zedek Medical Center, The Hebrew University, Jerusalem, - - 2014
Background: Minipuberty describes transient activation of the hypothalamic-pituitary-gonadal axis occurring during the first few months of life. Hormone levels during minipuberty were described in only a few Prader-Willi syndrome (PWS) infant boys and have not been reported in PWS infant girls. Objectives: To measure gonadotropins and gonadal hormones in PWS ...
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