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Daly Kathleen A KA Department of Otolaryngology, University of Minnesota Medical School, Minneapolis, MN, - - 2014
A randomized trial of an investigational 9-valent pneumococcal conjugate vaccine (PCV-9) or placebo given to pregnant women during the last trimester to prevent early infant otitis media (OM) was conducted. All infants received Prevnar(®) at 2, 4, 6, and 12 months. Clinic and adverse event records were reviewed to identify ...
Simons F Estelle R FE Department of Pediatrics & Child Health, Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address: - - 2014
In this rostrum we aim to increase awareness of anaphylaxis in infancy in order to improve clinical diagnosis, management, and prevention of recurrences. Anaphylaxis is increasingly reported in this age group. Foods are the most common triggers. Presentation typically involves the skin (generalized urticaria), the respiratory tract (cough, wheeze, stridor, ...
Gad GhadaI G Departments - - 2014
Abstract Objective: to evaluate the diagnostic value of antimicrobial peptide(Cathelicidin), LL-37,in congenital pneumonia and its relation to 25 hydroxycholecalciferol [(25 OH)D] status. Methods: The study included 30 neonates with congenital pneumoniaandculture proven sepsis admitted to neonatal intensive care unit of Ain Shams Universityand 30 healthy neonates as control group.All neonates ...
Magalhães Mauricio M Division of Neonatology, Department of Pediatrics, Santa Casa de São Paulo, São Paulo, - - 2014
Neonatal hypoxic-ischemic encephalopathy is associated with high morbidity and mortality. Studies have shown that therapeutic hypothermia decreases neurological sequelae and death. Our aim was therefore to report on a three-year experience of therapeutic hypothermia among asphyxiated newborns. Retrospective study, conducted in a university hospital. Thirty-five patients with perinatal asphyxia undergoing ...
Harrison Tondi M TM Principal Investigator, Assistant Professor, Center for Cardiovascular & Pulmonary Research, The Research Institute at Nationwide Children's Hospital, 700 Children's Drive, JW4989, Columbus, OH, 43205; College of Medicine, The Ohio State University, Columbus, - - 2014
The quality of maternal-infant interaction is a critical factor in the development of infants' autonomic function and social engagement skills. In this secondary data analysis, relationships among infant and maternal affect and behavior and quality of dyadic interaction, as measured by the Parent-Child Early Relational Assessment, and infant autonomic function, ...
Keating Elizabeth M - - 2014
Background: Beriberi is endemic in South-east Asia. Diagnosis is based on clinical findings, but correlation of clinical features with blood thiamine concentrations is uncertain. Objectives: To investigate in tachypnoeic Cambodian infants the correlation between whole blood thiamine diphosphate (TDP) concentrations, clinical findings and blood TDP levels after therapy. Methods: Infants ...
Chen Yiqin Y National Research Centre for Environmental Toxicology (Entox), The University of Queensland, Australia. Electronic address: - - 2014
Assessing blood concentration of persistent organic pollutants (POPs) in infants is difficult due to the ethical and practical difficulties in obtaining sufficient quantities of blood. To determine whether measuring POPs in faeces might reflect blood concentration during infancy, we measured the concentrations of a range of POPs (i.e. polychlorinated biphenyls ...
Wright Karen D KD Division of Neuro-oncology, Department of Oncology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Mail Stop 260, Memphis, TN, 38105, USA, - - 2014
High-dose methotrexate (HD-MTX) has been used to treat children with central nervous system tumors. Accumulation of MTX within pleural, peritoneal, or cardiac effusions has led to delayed excretion and increased risk of systemic toxicity. This retrospective study analyzed the association of intracranial post-resection fluid collections with MTX plasma disposition in ...
Clemente Maria Grazia MG Department of Pediatrics, Johns Hopkins Medical Institutions, Baltimore, - - 2014
To analyze the prevalence of acute asymptomatic group A and C rotavirus (RV-A and RV-C) infection in neonates with cholestasis. Participants were infants <180 days of age with cholestasis (serum direct or conjugated bilirubin >20% of total and ≥2 mg/dL) enrolled in the Childhood Liver Disease Research and Education Network during RV ...
Scalais Emmanuel E Division of Pediatric Neurology, Department of Pediatrics, Centre Hospitalier de Luxembourg, Luxembourg City, - - 2014
In neonates, very long chain acyl-CoA dehydrogenase (VLCAD) deficiency is often characterized by cardiomyopathy, hepatic encephalopathy, or severe hypoketotic hypoglycemia, or a combination thereof. The purpose of this study was to further elucidate a familial VLCAD deficiency in three patients, two of whom died in the neonatal period. We report ...
Iskander Iman I Departments of Pediatrics, - - 2014
Bilirubin/albumin ratio (B/A) may provide a better estimate of free bilirubin than total serum bilirubin (TSB), thus improving identification of newborns at risk for bilirubin encephalopathy. The objective of the study was to identify thresholds and compare specificities of TSB and B/A in detecting patients with acute and posttreatment auditory ...
Qubty William F WF Division of Child Neurology, Mayo Clinic, Rochester, - - 2014
The clinical characteristics of obstructive sleep apnea (OSA) in infants have been insufficiently characterized. Our aim was to describe identifiable comorbidities in infants with obstructive sleep apnea, which may assist in recognizing these patients earlier in their disease course and help improve management. This was a single-center, retrospective study involving ...
Mansour Fatima F Surgery Unit, UCL Institute of Child Health and Great Ormond Street Hospital for Children, 30 Guilford Street, London, WC1N 1EH, - - 2014
Sodium is thought to be critical to growth. Infants who have an ileostomy may suffer from growth faltering, as sodium losses from stomas may be excessive. Urinary sodium measurements may indicate which patients could benefit from sodium supplementation; however, there is no consensus on what level of urinary sodium should ...
Longardt A C AC Department of Neonatology, Charité University Medical Center, Berlin, - - 2014
Background/Objectives:Preterm infants have low vitamin A stores at birth, and parenteral administration of high-dose vitamin A reduces pulmonary morbidity. The aim was to characterize vitamin A transport and status.Subjects/Methods:Prospective study of 69 preterm infants (median birth weight 995 g, gestational age 28 weeks), in which 51 received 5000 IU vitamin A three ...
Garland J S JS Department of Pediatrics, Wheaton Franciscan Healthcare-St Joseph Hospital, Milwaukee, Wisconsin, - - 2014
To determine the frequency of tracheal pepsin in ventilated neonates and whether the angle of head elevation was associated with tracheal pepsin. Serial trachael samples (day 3, 7, 14, 21, 28 days of ventilation) were obtained from intubated, ventilated very low birth weight infants. Presence of tracheal pepsin was determined ...
Abdelmogheth Anas-Alwogud A AA Departments of Child Health, Sultan Qaboos University Hospital, Muscat, - - 2014
The aim of this study was to describe the pattern of viral infections in infants and children admitted to the Paediatric Intensive Care Unit (PICU) at Sultan Qaboos University Hospital (SQUH) in Muscat, Oman. A retrospective review of patient records was carried out on all patients admitted to the PICU ...
Anderssen Sven-Harald SH Department of Pediatrics, Sykehuset Østfold, Fredrikstad, - - 2014
This study aimed to evaluate the reproducibility of macronutrient measurements of domestic pooled human milk from mothers with preterm infants and to see how the results affected human milk fortifications. We asked 28 new mothers to express their breast milk for 24 hours on two consecutive days and repeat the ...
Casas Maribel M Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain. Electronic address: - - 2014
Low-level exposure to polychlorinated biphenyl-153 (PCB-153) and dichlorodiphenyldichloroethylene (p-p'-DDE) can impair fetal growth; however, the exposure-response relationship and effect modifiers of such association are not well established. This study is an extension of an earlier European meta-analysis. Our aim was to explore exposure-response relationship between PCB-153 and p-p'-DDE and birth ...
Abbasoglu Aslihan A Division of Neonatology, Department of Pediatrics, Baskent University Faculty of Medicine, Ankara, Turkey. Electronic address: - - 2014
Elevated serum levels of neuron-specific enolase (NSE) was initially assumed to be specific to neuronal tumors (particularly neuroblastoma), but is now known to accompany nontumoral conditions and tumors other than neuroblastomas. There is a need to establish normal ranges for NSE, especially in early infancy. The aims of this study ...
Gaensbauer James T JT Departments of Pediatrics Center for Global Health, Colorado School of Public Health, Aurora, USA - - 2014
To determine whether immune function is impaired among HIV-exposed but uninfected (HEU) infants born to HIV-infected mothers and to identify potential vulnerabilities to vaccine preventable infection, we characterized mother-to-infant placental transfer of Haemophilus influenzae type b-specific IgG (Hib-IgG), and levels and avidity after vaccination in Ugandan HEU infants and in ...
Reed Susan G SG Medical University of South Carolina , Charleston, South - - 2014
Abstract The purpose of this study was to investigate infant oral mutans streptococci (MS) by feeding method and by the mother's oral MS status. For this cross-sectional data collection, full-term infants at 4-6 weeks of age and their mothers were tested for oral MS using the Dentocult(®) SM chairside test ...
Zakaria Dala D Division of Pediatric Cardiology, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, - - 2014
Right ventricular (RV) function is reduced in infants with pulmonary hypertension (PH) but echocardiographic assessment can be challenging. We sought to determine the role of tricuspid annular plane systolic excursion (TAPSE) in infants with PH and compared it with other markers such as tricuspid annular S' and RV fractional area ...
Hesla Helena Marell HM Sachs' Children and Youth Hospital, Södersjukhuset, Stockholm, Sweden; Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, - - 2014
An anthroposophic lifestyle, which has been associated with reduced allergy risk in children, has several characteristics that could influence gut microbiota. This study aimed to investigate the impact of anthroposophic lifestyle as well as specific early life exposures, on the gut microbiota. In total, 665 stool samples from 128 mother-child ...
Stein Michal M Wolfson Medical Center, Holon, Israel The Sackler School of Medicine, Tel Aviv University, Tel Aviv, - - 2014
In this prospective study, we examined the usefulness of C-reactive protein (CRP), soluble triggering receptor expressed on myeloid cells (s-TREM-1), and procalcitonin (PCT), in identifying serious bacterial infection (SBI) among neonates. Infants younger than 3 months with suspected SBI were included and serum concentrations of CRP, PCT, and s-TREM-1 were ...
Hulzebos Christian V CV Department of Pediatrics, Beatrix Children׳s Hospital, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands. Electronic address: - - 2014
Treatment for unconjugated hyperbilirubinemia is predominantly based on one parameter, i.e., total serum bilirubin (TSB) levels. Yet, overt kernicterus has been reported in preterm infants at relatively low TSB levels, and it has been repeatedly shown that free unconjugated bilirubin (freeUCB) levels, or bilirubin/albumin (B/A) ratios for that matter, are ...
Bharathi B B Division of Neonatology, Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, 605 006, - - 2014
To identify biomarkers for neuronal injury and outcome in perinatal asphyxia. This prospective cohort study was done in authors' level III NICU involving 80 neonates - 40 babies with perinatal asphyxia and 40 weight and gender matched normal neonates. Levels of cytokines IL-6, IL -1β, IL-2 and TNF -α in ...
Chen Wen W Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, - - 2014
The effects of long-term excessive maternal iodine intake on neonatal thyroid function is less known. This study aimed to assess the effects of maternal excessive iodine intake from drinking water on thyroid functions of both mothers and their neonates. This observational study was performed in high iodine (HI) areas and ...
Hibbs A M AM 1] Department of Pediatrics, Case Western Reserve School of Medicine, Cleveland, OH, USA [2] Division of Neonatology, Department of Pediatrics, Rainbow Babies and Children's Hospital, Cleveland, OH, - - 2014
Objective:We aimed to determine whether vitamin D exposure, as estimated by use of multivitamins, is positively or negatively associated with recurrent wheezing in infants born preterm.Study Design:This prospective cohort study enrolled 300 infants, born at 28(0/7) to 34(6/7) weeks gestational age, and conducted follow-up at 3-, 6-, 9- and 12-month ...
Ozguven Ali Aykan AA Department of Pediatric Hematology and Oncology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey, - - 2014
To determine outcome of neuroblastoma (NBL) in children under 18 mo of age who had been treated with national protocols. The characteristics and treatment outcomes of 27 children were evaluated retrospectively. The event-free survival (EFS) at 60 and 108 mo were 84.7 % ± 7.7 and 72.6 % ± 7.7, respectively. The overall survival (OS) was 91.7 % ± 8 at ...
Zionts Lewis E LE Orthopaedic Institute for Children, 403 West Adams Boulevard, Los Angeles, CA 90007. E-mail address: - - 2014
The Ponseti method is an established approach to treating idiopathic clubfoot in infants. The method involves a period of cast immobilization and postcorrective bracing that potentially interferes with normal movements of the lower extremities. In the present study, we investigated the age at which infants who had idiopathic clubfoot treated ...
Edmunds Suzanne M SM From the Departments of Anesthesiology and Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, - - 2014
Alcohol ingestion in the pediatric patient can be life threatening. Younger patients consume larger volumes per body weight with accidental ingestions, and children have more serious adverse effects at lower blood alcohol levels. Complications of alcohol poisoning can include hypothermia, hypoglycemia, seizures, coma, and death. We present the course of ...
Shim So-Yeon SY Division of Neonatology, Ewha Womans University, School of Medicine, Seoul, - - 2014
Background: Even preterm infants with normal magnetic resonance imaging (MRI) results are at greater risk for neuromotor dysfunction. Objectives: Our aim was to compare serial diffusion tensor imaging (DTI) data from preterm infants without apparent brain abnormalities on magnetic resonance imaging with those from term controls and to investigate the ...
Bansal Seema S 1Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL. 2Children's National Medical Center, Washington, - - 2014
To determine the prevalence of acute symptomatic seizures in infants with supratentorial intracranial hemorrhage, to identify potential risk factors, and to determine the effect of acute seizures on long-term morbidity and mortality. Children less than 24 months with intracranial hemorrhage were identified from a neurocritical care database. All patients who ...
Friedman Eleanor E EE Department of Epidemiology, Tulane School of Public Health and Tropical Medicine, New Orleans, Louisiana, United States of - - 2014
Dengue is a mosquito-borne disease that is common in many tropical and subtropical areas. Dengue infections can occur at any age and time in the lifespan, including during pregnancy. Few large scale studies have been conducted to determine the risk of preterm birth (PTB) and low birthweight (LBW) for infants ...
Koontz M B MB Department of Pediatrics, Rainbow Babies & Children's Hospital, Case Western Reserve University, Cleveland, OH, - - 2014
Rapid weight gain in infancy has been established as a risk factor for the development of later obesity. We aimed to investigate the role of changes in infant body composition (assessed via total body electrical conductivity) on the development of overweight/obesity in mid-childhood. Fifty-three term infants were evaluated at birth, ...
Eckhardt Cara L CL School of Community Health, Portland State University, Portland , USA - - 2014
Abstract Background: Maternal vitamin D status in pregnancy is linked to foetal growth and may impact infant growth. Aim: This study examined the association between maternal vitamin D status and infant anthropometry. Subjects and methods: Data came from n = 2473 mother-child pairs from the 12-site US Collaborative Perinatal Project (1959-1965). Maternal ...
Magoha Happy H Ghent University, Faculty of Bioscience Engineering, Department of Food Safety and Food Quality, Research group Food Chemistry and Human Nutrition - nutriFOODchem (partner in Food2Know), Coupure links 653, 9000 Ghent, Belgium; Open University of Tanzania (OUT), Department of Food and nutrition, P.O. Box 23409, Dar es Salaam, - - 2014
The carry-over of fumonisin B1 from contaminated feed into dairy milk also suggests its carry-over from contaminated food into breast milk. This study assessed fumonisin B1 contamination in breast milk and associated exposures of infants under six months of age. Breast milk samples were collected from 131 lactating mothers and ...
England Jasmin Tamsut JT Department of Pediatrics, UCLA Geffen School of Medicine, Los Angeles, - - 2014
Serum procalcitonin (PCT) concentrations have been studied as a diagnostic test for serious bacterial infections (SBIs) in children. However, the utility of a single measurement in the evaluation of SBIs in febrile infants younger than 91 days is not clear. Use a systematic review and meta-analysis to determine: 1) the ...
Hagadorn James I JI Division of Neonatology, Connecticut Children's Medical Center, Hartford, Connecticut Department of Pediatrics, University of Connecticut School of Medicine, Farmington, Connecticut Connecticut Human Milk Research Center, Hartford, Connecticut - - 2014
Background: Use of donor human milk (DHM) is increasing, but criteria for its use are not well defined. Materials and Methods: We conducted a 34-question Internet-based survey of medical directors of U.S. level 3 and level 4 neonatal intensive care units (NICUs), with the goal of describing specifics of policies ...
Aronson Paul L PL Department of Pediatrics, Section of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut; - - 2014
Variation in patient care or outcomes may indicate an opportunity to improve quality of care. We evaluated the variation in testing, treatment, hospitalization rates, and outcomes of febrile young infants in US pediatric emergency departments (EDs). Retrospective cohort study of infants <90 days of age with a diagnosis code of ...
Idborg Helena H Rheumatology Unit, Department of Medicine, Karolinska University Hospital, - - 2014
We have investigated the clinical feasibility of the major urinary metabolite of prostaglandin (PG) E2, tetranor-PGEM, as a biomarker of inflammation in infants with fever. We tested two different and clinically relevant sampling methods, using self-adhesive urinary bags or gauze pads, with respect to stability of tetranor-PGEM and ease of ...
Tang Y-F YF Department of Gastroenterology, The General Hospital of Beijing Military Command, Beijing, China; Dalian Medical University, Dalian, - - 2014
Conventional methods of screening for Hirschsprung disease (HD) in newborns (barium enema, BE; anorectal manometry, ARM; rectal suction biopsy, RSB) have limitations and/or are invasive. High-resolution anorectal manometry (HR-ARM) is a minimally invasive technique that has potential to overcome most of these limitations, but normative data and performance characteristics have ...
Yoshino Atsunori A Department of Nephrology, Dokkyo Medical University, Koshigaya Hospital, 2-1-50, Minamikoshigaya, Koshigaya, Saitama, 343-8555, Japan, - - 2014
Although congenital anomalies of the kidney and urinary tract (CAKUT) are the most common cause of pediatric end-stage renal disease (ESRD), little is known about the characteristics exhibited in the infantile period by CAKUT patients who develop ESRD. Further, an efficient screening method for CAKUT diagnosis is not available currently. ...
Reijman Sophie S Centre for Child and Family Studies, Leiden University, P.O. Box 9555, 2300 RB, Leiden, The - - 2014
Deviant physiological reactivity to infant stimuli has been suggested to underlie maladaptive parenting behavior. Our study involved 44 maltreating and 42 non-maltreating mothers. During a standardized cry paradigm, mothers listened to nine cry sounds of varying pitches. Saliva was collected at baseline, after each cry sound, and after a recovery ...
Karabayir Nalan N Pediatrics Department, Faculty of Medicine, Istanbul Medipol University, Istanbul, Turkey, - - 2014
Approximately 5 % of infants born with a meconium-stained amniotic fluid (MSAF) develop meconium aspiration syndrome (MAS). Early recognition of infants at highest risk for the development of MAS and the prediction of disease severity are important for optimizing the clinical strategies for prevention and treatment. The aim of the present ...
Ogawa Yuki Y Department of Clinical Chemistry and Informatics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto, 862-0973, Japan, - - 2014
This study aimed to determine the population pharmacokinetics of doxapram in low-birth-weight (LBW) infants. A total of 92 serum concentration measurements that were obtained from 34 Japanese neonates were analyzed using nonlinear mixed-effect modeling (NONMEM). Estimates generated by NONMEM indicated that clearance of doxapram (CL; L/kg/h) was affected by postmenstrual ...
Aksu Tekin T Faculty of Medicine, Department of Pediatrics, Division of Neonatology, Gazi University, Ankara, - - 2014
Abstract Objective: To compare interleukine-10 (IL-10) and total antioxidant capacity (TAC) levels after breast milk storage by studying premature and term mothers' colostrum and mature milk and by analyzing those levels relative to gestational week. Methods: Fifty-four colostrum and mature breast milk samples were collected from both premature and term ...
Harris Gerald G Department of Environmental and Occupational Medicine, Rutgers University, Robert Wood Johnson Medical School, Piscataway, NJ, USA. Electronic address: - - 2014
There is interest in determining the relationship between fine particulate matter air pollution and various health outcomes, including birth outcomes such as term low birth weight. Previous studies have come to different conclusions. In this study we consider whether the effect may vary by location and gestational period. We also ...
Smith Cameron - - 2014
Preference for sons in India has resulted in a skewed sex ratio at live birth, probably as a consequence of female feticide. However, it is unclear if these cultural preferences are also currently present in communities who have emigrated from India to England and Wales. Data of all live births ...
Bjerregaard-Andersen M M Bandim Health Project, INDEPTH Network, Bissau, Guinea-Bissau; Research Center for Vitamins and Vaccines, Statens Serum Institute, Copenhagen, - - 2014
To examine mortality and hospitalisations among infant twins and singletons after the perinatal period in Guinea-Bissau. The study was conducted from September 2009 to November 2012 by the Bandim Health Project (BHP). Newborn twins and unmatched singleton controls were included at the National Hospital Simão Mendes in the capital Bissau. ...
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