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Lowry R B - - 1985
We present clinical findings in infants from three kindreds (two Hutterite and one Mennonite) with an apparently unique, fatal disorder. The major manifestations consist of severe intrauterine growth retardation, congenital contractures, and tense skin which is easily eroded. The skin is tightly drawn over the face, giving an abnormal appearance ...
Bennet R - - 1985
This report concerns a case of neonatal herpes zoster associated with maternal gestational varicella. The child developed skin lesions at 18 days of age virologically confirmed to be varicella-zoster. The baby also had encephalitis and aspiration probably due to bulbar paralysis. Multiple small necrotic areas were found in the thalamus ...
Rhead W J - - 1985
Untransformed diploid skin fibroblasts from eight normal adults, aged 24 to 74 years, catabolized several 14C-labeled substrates less effectively than cells from ten normal male infants. 14C-labeled substrate metabolism was quantitated either by measuring the evolution of 14CO2 from the 14C-labeled compounds or the incorporation of 14C into cellular protein ...
Hyman P E - - 1985
In a double-blind, placebo controlled study of 10 infants with upper gastrointestinal motor disorders, metoclopramide (1 mg/kg, intravenous) but not bethanechol (0.075 mg/kg, subcutaneous), significantly increased the fractional rate of gastric emptying following a 5% glucose meal. Infants were tested on 3 consecutive days with a phenol red dye-dilution technique ...
Luck S R - - 1985
Primary tissue closure of gastroschisis remains controversial. Some surgeons routinely place a silicone rubber sheet silo over the exposed bowel, planning a staged closure. In the past 14 1/2 years, we have cared for 106 newborns with gastroschisis, closing the defect primarily in 80%. The success of this technique depends ...
Evans N J - - 1985
The preterm infant's skin is a poor barrier to the absorption of chemical agents. The possibility of turning this to the infant's advantage was explored by using the percutaneous route to administer theophylline. A standard dose of theophylline gel, equivalent to 17 mg anhydrous theophylline, was applied to an area ...
Updike P A - - 1985
This study investigated evidence of a circadian rhythm in the physiologic variables of transcutaneous oxygen (tcPO2) level, pulse rate, respiratory rate, frequency of respiratory pauses, and skin temperature in six 34- to 37-week-preterm infants. A value for each variable was noted every 30 minutes for 24 hours, providing 245 observations ...
Perlman M - - 1985
There are four types of neonatal respiratory depression. Most infants who require resuscitation have clearly depressed respiration at birth. The onset is prenatal in these cases. However, other infants appear normal at birth, cough and breathe a few times, but become acutely depressed in the first minute or so. A ...
Honour J W - - 1985
Three infants with X-linked ichthyosis have been observed following pregnancies in which placental sulphatase deficiency (PSD) was suggested prenatally by low oestrogen excretion and an abnormal urinary steroid excretion pattern. This was confirmed in two cases by the absence of placental enzyme activity. In one case labour was spontaneous but ...
Hawk R J - - 1985
Toxic epidermal necrolysis was documented in a 6-week-old infant with Klebsiella pneumoniae sepsis who received many medications. We inoculated infant mice with the K. pneumoniae isolate but were unable to produce histologic changes resembling those seen in our patient. This condition should be included in the differential diagnosis of severe ...
Saito M - - 1985
Diploid human infant skin fibroblasts cultured from normal infants and Gaucher disease infants, with genetically defective lysosomal glucosylceramide:beta-glucohydrolase activity, had a full range of homologous glycosphingolipids from the simplest (glucosylceramide) to higher neutral derivatives (lactosyl-, trihexosyl- and tetrahexosylceramide) and anionic sialo derivatives (gangliosides) (sialosyllactosyl-, disialosyllactosyl-, sialosylgangliotriaosyl-, and mono- and disialosylgangliotetraosylceramide). ...
Rutter N - - 1985
Emotional sweating from the palm of the hand occurs from birth in the term infant and can be conveniently measured with a skin evaporimeter. Such measurements provide objective information about an infant's state of arousal that might be useful to neonatologists and psychologists who are interested in studying stress and ...
Ornvold K - - 1985
A 2 300 g male infant presented at birth with multiple, firm, bluish skin nodules, petechiae and thrombocytopenia. Physical examination was otherwise normal and no biochemical signs of organ dysfunction were found. A skin biopsy, done on the second day of life, was consistent with self-healing reticulohistiocytoma by light and ...
Cheesbrough J S - - 1984
In a series of 519 intravenous cannulae with valved injection side-ports the incidence of cannula-related local inflammation was 25.2% and bacteraemia 0.2%. Severe local inflammation was associated with a longer mean duration of cannulation, 59.4 v. 81.4 h (P = less than 0.05). There was no significant association between the ...
Maurer A - - 1984
Skin water loss of preterm infants, nursed naked in incubators under thermoneutral conditions, was assessed by a method based on the measurement of water vapor pressure gradient close to the skin surface. The corresponding skin evaporative heat loss was calculated using an energy equivalent of 0.58 kcal/g water vaporised. During ...
Fujiki H - - 1984
Synthetic analogues (indolactams) related to the tumor promoter teleocidin were synthesized chemically. Of four indolactam-Vs lacking the monoterpenoid moiety of native teleocidin, (-)-indolactam-V bound to the 12-O-tetradecanoylphorbol-13-acetate receptor in cell membranes and induced both adhesion of HL-60 cells and ornithine decarboxylase activity in mouse skin, although its effects were weaker ...
Carlson M - - 1984
Four infant macaques between the ages of 3.0 and 5.1 weeks and three juvenile macaques between the ages of 79.9 and 109.3 weeks received unilateral lesions of all cytoarchitectural fields (Brodmann's areas 3, 1 and 2) in the hand area of the postcentral gyrus. These total SmI-lesioned infants acquired the ...
Nakashima A K - - 1984
From September 14, 1981 to February 28, 1982, an epidemic of bullous impetigo caused by a penicillin/tetracycline resistant strain of Staphylococcus aureus, phage type 3A/3C, occurred in a newborn nursery in Louisville, Kentucky. Twenty of 1,181 (1.7%) infants at risk developed disease during the six-month epidemic period. Clinically all case-infants ...
Seeberg S - - 1984
The incidence and types of staphylococcal purulent lesions were prospectively studied among 3602 newborn infants. During an epidemic of post-discharge pyoderma, 87 per cent of all Staphylococcus aureus isolates from lesions could be traced to the nursery. The risk of post-discharge disease was related to the degree of staphylococcal skin ...
Bryant C A - - 1984
The purpose of this study was to identify a skin wound cleanser that could be used safely to cleanse lacerations of the periorbital region. The irritation and toxicity to the eye of the commercially available skin wound cleansers were quantitated using numerical values and weights for the ocular lesions in ...
Kobayashi K - - 1984
A 3-month-old Japanese female infant, with persistent navel infection due to Pseudomonas aeruginosa since birth and recurrent bacterial skin infections, was found to have a severe abnormality of neutrophil adhesion on a surface, leading to a lack of chemotaxis and a mild impairment of phagocytosis. Neither neutrophil bactericidal activity nor ...
Chow A W - - 1984
We report a unique mother-infant pair with variant staphylococcal toxic shock syndrome and probable intrapartum transmission to the neonate. Diagnosis of probable toxic shock was supported by the finding of fever, desquamative skin rash, multi-organ system involvement, and pronounced mucocutaneous manifestations, including strawberry tongue, dermal swelling, pharyngitis, and vulvar edema, ...
Van Asperen P P - - 1984
We examined the development of skin test reactivity and clinical allergen sensitivity in infancy. Seventy-eight infants of atopic parents were skin prick tested every 4 mo from 4 to 16 mo and an additional 57 of these infants were tested at 20 mo. Wheal diameters were recorded for histamine (1 ...
Clemmensen O J - - 1984
Suction blister fluid from the abdominal skin of 14 healthy subjects was examined for the presence of split products of complement C3 (C3-split) as an indicator of complement activation before and after treatment with either UVA or PUVA. Following PUVA a significant increase in C3-split was found (p less than ...
Hazen P G - - 1983
Two male infants manifested a complex of symptoms and signs that we believed represented a distinctive hypersensitivity disease, with features of acute febrile neutrophilic dermatosis and allergic vasculitis. Both were less than 1 year of age, and both acquired their disease during or after an upper respiratory illness. Each infant ...
Culp C E - - 1983
Obstruction of the outlet of the apocrine duct adjacent to the skin surface, with subsequent rupture into the intradermal plane, initiates the inflammatory condition termed "hidradenitis suppurativa." The chronic manifestations of the process, indicated by recurrent abscess formation, draining sinuses, skin fistulas, and an intense cicatricial response, usually affect the ...
Lozoff B - - 1983
To determine whether women giving birth in traditional societies maintained early and extended skin-to-skin contact with their neonates and nursed them immediately, descriptions of childbirth in 186 non-industrial societies were examined. Most cultures made no special effort to get mothers in body contact with infants in the minutes after birth: ...
Tomer A - - 1983
A male infant, born at 40 weeks' gestation of a 27-year-old mother, presented at delivery with three scalp lesions, 2 to 4 cm in diam, covered with necrotic tissue and devoid of hair. The infant was born by natural vertex delivery within 2 hours of membrane rupture; birth weight was ...
Yokoya S - - 1983
The urocanic acid content of the skin was measured photometrically in a large number of normal and histidinemic infants. A very high content was demonstrated in the normal newborn infants, followed by a rapid decrease throughout early infancy. In contrast, 36 measurements in 17 infants with histidinemia revealed a much ...
Okada S - - 1983
We observed a 3-month-old Japanese female infant with severe psychomotor retardation, coarse facial appearance, hepatosplenomegaly, and dysostosis multiplex. Only beta-galactosidase was found to be deficient when the routine lysosomal hydrolase assay was performed on the patient's lymphocytes at 6 months of age. At first GM1-gangliosidosis type 1 seemed the most ...
Chesney P J - - 1983
A 2-month-old premature infant had an extensive exfoliative dermatitis with flaccid bullae, mucous membrane involvement, thrombocytopenia, and an elevated creatinine kinase level. A subepidermal cleavage plane with numerous necrotic epidermal cells and a polymorphonuclear cell infiltrate were present on a skin biopsy specimen. The isolates of Staphylococcus aureus obtained at ...
Whelan D T - - 1983
We report on the clinical, radiological and biochemical features of mucolipidosis II in three infants. One with subtle phenotypical findings died at 2 weeks of age without a specific diagnosis. A sibling who died at 2 years of age and another infant, presently 3.5 years of age manifest all the ...
Sacks L M - - 1983
Umbilical and axillary skin cultures for bacteria and yeast were obtained within two hours of birth from 108 term infants born vaginally under sterile (52) and nonsterile (56) conditions. The skin of infants born under nonsterile conditions was more frequently colonized (91%) than that of infants born under sterile conditions ...
Harpin V A - - 1983
The barrier properties of the skin were examined in 223 studies in 70 newborn infants of 25 to 41 weeks' gestation, aged from 1 hour to 26 days. Percutaneous drug absorption was studied by observing the blanching response to solutions of 1% and 10% phenylephrine applied to a small area ...
Younger B - - 1982
A 41/2-month-old infant, the product of a normal pregnancy, labor, and delivery had a folded right ear at birth. At the apex of the fold there was a crusted erythematous nodule. A biopsy specimen of this nodule at age 41/2 months showed collections of calcium surrounded by epithelioid histiocytes in ...
Vahlquist A - - 1982
Pro-vitamin A(beta-carotene) and the predominant forms of vitamin A in human skin (retinol and dehydroretinol) were analyzed in hydrolyzed specimens from 4 cadavers and 22 healthy subjects. Beta-carotene was identified in extracts of epidermis by its specific absorption spectrum. Vitamin A was determined by high-pressure liquid chromatography. The concentrations were ...
Friis-Hansen B - - 1982
No rise in the boron content of the plasma of 22 newborn infants was demonstrated following repeated daily application of a water-emulsifying ointment containing the equivalent of 3% boric acid to the napkin region. The mean plasma-boron concentration fell over 5 days from a pretreatment value of 0.49 to 0.29 ...
- - 1982
A study group was formed to undertake further investigation of the problems involved in the classification of anorectal anomalies. At first, a registration form including standardized techniques for clinical and roentogenologic investigation was defined, and then 254 cases were collected and analyzed by referring these materials to the International Classification ...
Lyerly D M - - 1982
Examination of the biological activities of the two known toxins of Clostridium difficile revealed that one of the toxins (toxin A) elicited a hemorrhagic fluid response in rabbit intestinal loops and a positive fluid response in infant mice. The other toxin (toxin B) did not produce a significant fluid response ...
Curry M A - - 1982
The problem was to determine the effect of skin-to-skin contact between mother and infant during the first hour following delivery on later maternal attachment behavior and self concept. Twenty primiparous women were randomly assigned skin-to-skin contact with their infant during the first hour after birth. There were no significant differences ...
Williams J F - - 1982
Multiple nodular skin lesions on an adults Saanen doe were found to be caused by demodectic mites. An identical condition developed in the daughter of the affected goat despite separation from the mother at 24 hours after birth. Of 7 other goats in contact with the doe, 2 had a ...
Stroud C E - - 1982
Almost all babies born in the United Kingdom are born in hospital and with the continuing improvements in neonatal care more survive than ever before, particularly those of very low birth weight. The use of the manipulative and invasive procedures so necessary to monitor and assist their healthy development often ...
Bollinger A - - 1981
Microneedles, 0.2 mm o.d., were connected to a microsyringe and mounted on a micromanipulator. Under microscopic control, 0.01 ml of a 25% solution of FITC-labeled dextran-40 or dextran-150 were injected into the subepidermis at the big toe near the nailfold or in the medial ankle region. Fluorescence intravital microscopy revealed ...
Lim M O - - 1981
A unique cas of dermal calcification occurred in a 14-month-old femal infant. Results of all pertinent laboratory data obtained on this patient were within normal limits except for an elevation of the heat labile fraction of alkaline phosphatase. A skin biopsy specimen showed irregularly shaped deposits of calcified osteoid with ...
Wilkinson S - - 1981
An infant had a persistent ulcerative nodular diaper dermatitis with negative laboratory findings for pathogens. With bland therapy and avoidance of powdering, the lesions cleared. This reaction was considered, without proof, to be granuloma gluteale infantum. This condition should be considered in the differential diagnosis of the various types of ...
Rebora A - - 1981
The correlation of recovery of Candida albicans from the skin, rectum and faeces of four clinically distinct groups of infants with napkin (diaper) dermatitis has been studied. We found that: (I) C. albicans is largely and constantly present both on the skin and in faeces of subjects with clinically overt ...
Azmy A - - 1981
Torsion of the penis is a rare anomaly, believed to be due to abnormal skin attachment and not to any structural abnormality of the corpora. The rotation is usually to the left in a counter-clockwise fashion. The urethral meatus is placed in a oblique position and the median raphe makes ...
Arlette J P - - 1981
Zinc deficiency dermatitis is a recognized complication of prolonged total parenteral nutrition (TPN) in adults and children. Ten cases of a characteristic dermatosis developing in premature infants with hypozincemia while on long-term TPN are described. The infants presented a defined group of premature neonates who were born between 25 and ...
Simkin R J - - 1981
This paper deals with the concept of alternative birthing. The reasons for home births versus hospital births are discussed. A general model of an alternative birthing centre (ABC) is described. Some concepts common to alternative birthing are discussed, followed by a discussion of problems involved in initiating an alternative birthing ...
Gonzalez J - - 1981
A 4-month-old infant was seen with hypokalemic metabolic alkalosis that was associated with prior application of liberal amounts of sodium bicarbonate (baking soda) to a diaper rash. After exclusion of other etiologies of the infant's acid-base disturbance, a complete resolution occurred following discontinuation of the baking soda applications. This case ...
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