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Hisamatsu Chieko C Division of Pediatric Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, - - 2014
In very low birth weight infants (VLBWI), intestinal obstruction (IO) tends to increase in severity due to the immaturity of the intestine and perinatal events. We examined the clinical comorbid factors related to IO in VLBWI. Clinical data of 160 VLBWI admitted to our neonatal intensive care unit from 2006-2011 ...
Neu Josef J University of Florida, Department of Pediatrics, Division of Neonatology, 1600 Southwest Archer Road, Human Development Building, HD 112, Gainesville, FL 32610, USA. Electronic address: - - 2014
One of the most controversial areas in neonatology is whether probiotics should be provided routinely to preterm infants to prevent necrotizing enterocolitis (NEC). This review provides the reader with a brief overview of NEC and current concepts of its pathophysiology, discusses the microbial ecology of the intestine in preterm infants ...
Markham Kara B KB Maternal Fetal Medicine Division, Department of Obstetrics & Gynecology, The Ohio State University College of Medicine, 395 West 12th Avenue, 5th Floor, Columbus, OH 43210, USA. Electronic address: - - 2014
Spontaneous preterm labor is a complex process characterized by the interplay of multiple different pathways. Prevention of preterm labor and delivery is also complicated. The most effective interventions for prevention of preterm birth (PTB) are progestin prophylaxis and lifestyle modifications, with cerclage placement also playing a role in selected populations. ...
Clark Sarah J SJ Child Health Evaluation and Research Unit, University of Michigan, Ann Arbor, MI. Electronic address: - - 2014
Vaccinating pregnant women and household contacts of infants is recommended for pertussis prevention. In structured abstraction of Web sites of Michigan birthing hospitals, we found only 36% contained any pertussis prevention information, and it usually required a specific search for pertussis. Hospitals should emphasize pertussis prevention as part of general ...
Arias-Llorente R P RP Service of Neonatology, AGCP, Hospital Universitario Central de Asturias, Oviedo, - - 2014
Appendicitis in the neonatal period is extremely rare. Its low incidence together with non-specific clinical symptoms often mean the diagnosis is delayed, leading to increased rates of peritonitis and mortality. We report the case of a 33-week premature infant, small for gestational age (1180 g at birth), clinically stable and ...
- - 2014
MPs have criticised the government for a lack of urgency in preventing deaths from sepsis.
Stokes Sean M SM Department of Surgery, Division of Pediatric Surgery, University of Kentucky, Lexington, Kentucky, - - 2014
Complicated necrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP) are major causes of mortality. We hypothesized that peritoneal drainage (PD) is more efficacious in SIP. Newborn infants with intestinal perforation treated with PD at our institution between 2007 and 2012 were divided into two groups: Group 1, infants with complicated ...
Cao Meng M Key Laboratory for Animal Disease-Resistant Nutrition of the Ministry of Education of China, Animal Nutrition Institute, Sichuan Agricultural University, Ya'an, - - 2014
It has been suggested that maternal nutrition during gestation is involved in the offspring's intestinal development. The aim of this study was to evaluate the effects of maternal nutrition on digestive and absorptive function of offspring at both birth and weaning with pig as model. Eighteen primiparous Landrace × Yorkshire gilts (ages ...
Khode S R SR MAHSA University College, ENT and Head Neck Surgery, Jalan Elmu Off Jalan University Campus, Kuala Lumpur, Selangor 59100, Malaysia. - - 2014
Congenital vallecular cyst is an uncommon, benign but potentially dangerous condition causing respiratory distress and stridor. It is associated with sudden upper airway obstruction resulting in death due to its anatomical location in neonates and infants. We reported a rare case of 2 months old male infant presented with respiratory ...
Nies Melanie M 1 Division of Pediatric Cardiology, Johns Hopkins Hospital, United States of - - 2013
Decades ago, mass-scale epidemiologic studies were undertaken to accurately describe the prevalence of congenital heart disease and associated malformations, and to identify inheritance patterns, teratogenic influence and aetiologic underpinnings. Despite phenomenal breakthroughs in molecular diagnosis of congenital heart disease, original population-based studies for detailed knowledge of prevalence, associated malformations, and ...
Neu Josef J Division of Neonatology, Department of Pediatric, University of Florida College of - - 2013
Emerging technologies derived largely from the Human Genome Project are being applied to evaluating the intestinal microbiota in preterm infants. The microbial ecology of the developing intestine is highly related to health and disease and new discoveries are emerging that will help us understand disorders in the development of the ...
Molgat-Seon Y - - 2013
A fully functional radiant warmer induced rapid and continuous increases in regional skin temperatures, heart rate, mean arterial blood pressure and respiratory rate in a newborn patient without corrective action. We report this case of passive overheating to create awareness of the risks associated with regulating radiant heat output based ...
Fleck Brian W - - 2013
Emerging data from randomised controlled trials of different pulse oximeter oxygen saturation (SpO2) target ranges shows that higher SpO2 targets are associated with a higher risk of severe retinopathy of prematurity. However, the trials have also shown that higher SpO2 targets are associated with improved survival. In the light of ...
Garcia C C Aix—Marseille Université CNRS, CRMBM UMR 7339 Marseille - - 2013
Premature births are increasing worldwide (about 15 millions per year) due to several reasons (an advanced maternal age, fertility treatments, stress, smoking, nutritional deficiencies) and lead to a high societal overall cost. Among neonatal care procedures, the clinical nutrition practices are essential to promote the development and to minimize the ...
Candel-Pau Júlia - - 2012
Objective After the introduction of a new protocol based on the early treatment with indomethacin for patent ductus arteriosus, the objective of this study was to assess the safety and efficacy of this new practice in comparison with the safety and efficacy of the conventional treatment in a high-risk population.Study ...
Zhang X - - 2012
Please cite this paper as: Zhang X, Kramer M. The rise in singleton preterm births in the USA: the impact of labour induction. BJOG 2012; DOI: 10.1111/j.1471-0528.2012.03453.x. Objective  To assess the extent to which increased rates of labour induction and caesarean section have contributed to the recent rise in preterm ...
Yamada Takashi - - 2012
OBJECTIVES: To determine whether a low serum folate level during the first trimester predicts subsequent late abortion, preterm birth, or fetal growth restriction (FGR). STUDY DESIGN: A prospective cohort study involving 5,075 women whose serum folate levels were measured during the first trimester. The participants were informed of their serum ...
Stewart Robert D - - 2012
OBJECTIVE: We sought to determine if uterine tachysystole, ≥6 contractions per 10 minutes, within the first 4 hours of labor induction, is associated with adverse infant outcomes. STUDY DESIGN: This was a prospective cohort study of 584 women ≥37 weeks' gestation undergoing induction of labor with 100 μg of oral ...
Wickremasinghe Andrea C AC Department of Pediatrics, University of California San Francisco, San Francisco, CA 94143-0544, - - 2012
To examine whether a change in the approach to managing persistent patent ductus arteriosus (PDA) from early ligation to selective ligation is associated with an increased risk of abnormal neurodevelopmental outcomes. In 2005, we changed our PDA treatment protocol for infants born at ≤27 6/7 weeks' gestation from an early ...
Demirel Gamze - - 2012
Patent ductus arteriosus is a common problem in very low birth weight infants. Prostaglandin synthesis inhibitors such as indomethacin and ibuprofen are widely used preferred medications for ductal closure but the question of which one should be preferred is controversial. There are some studies in the literature comparing their pharmacokinetics, ...
Marsh Abigail A AA Department of Psychology, Georgetown University, 37th and O Streets NW, Washington, DC 20057, USA. - - 2012
Oxytocin is a neuropeptide that is associated with increases in social affiliative behaviors, particularly toward infants. However, no previous study has investigated healthy adults' responses to infant faces following oxytocin administration. In addition, given that preliminary evidence suggests that a single-nucleotide polymorphism of the oxytocin receptor (OXTR) gene, rs53576, may ...
Slager Joan - - 2012
Premature effacement of the cervix, or short cervix, in the midtrimester of pregnancy currently represents the strongest predictor of spontaneous preterm birth. Numerous studies have examined the relationship between short cervix and preterm birth, and although differences in sensitivity and predictive value exist, the overwhelming consensus indicates that the risk ...
Mirea Lucia - - 2012
OBJECTIVE: To examine the association between treatment for patent ductus arteriosus (PDA) and neonatal outcomes in preterm infants, after adjustment for treatment selection bias. STUDY DESIGN: Secondary analyses were conducted using data collected by the Canadian Neonatal Network for neonates born at a gestational age ≤32 weeks and admitted to ...
Natarajan Girija - - 2013
Permanent ductal closure involves anatomic remodeling, in which transforming growth factor (TGF)-β appears to play a role. Our objective was to evaluate the relationship, if any, between blood spot TGF-β on day 3 and day 7 of life and patent ductus arteriosus (PDA) in extremely low birth weight (ELBW) infants. ...
Lembo S - - 2012
A female infant had been delivered prematurely at 33 weeks to a gravida 1, para 0, 32-year-old mother following normal spontaneous vaginal delivery. Because of persistent patent ductus arteriosus the new born underwent surgery after 30 days. Four months later, when the infant arrived at our observation, approximately 13 red, ...
Petraglia Felice - - 2012
Endometriosis is a chronic inflammatory disease affecting women's health. Pain and infertility are the major symptoms caused by a hormonal/immunological dysfunction, which causes an endometrial impairment. The same pathogenetic mechanisms are also associated with preterm birth: hormones, cytokines, neurohormones, and growth factors interact in modulating extracellular matrix and prostaglandin secretion, ...
Feltovich Helen - - 2012
Spontaneous preterm birth is a heterogeneous phenotype. A multitude of pathophysiologic pathways culminate in the final common denominator of cervical softening, shortening, and dilation that leads to preterm birth. A precise description of specific microstructural changes to the cervix is imperative if we are to identify the causative upstream molecular ...
Mezu-Ndubuisi Olachi J - - 2012
Persistent patency of the ductus arteriosus is a major cause of morbidity and mortality in premature infants. In infants born prior to 28 weeks of gestation, a haemodynamically significant patent ductus arteriosus (PDA) can cause cardiovascular instability, exacerbate respiratory distress syndrome, prolong the need for assisted ventilation and increase the ...
Mercanti Isabelle - - 2012
The patency of the ductus arteriosus has ever been considered as a pathological situation in preterm infants and one likely cause of mortality and morbidity, including broncho-pulmonary dysplasia, necrotizing enterocolitis, intraventricular haemorrhage, retinopathy of prematurity. The incidence of patent ductus arteriosus is inversely proportional to gestational age and infants with ...
Schneider Douglas J - - 2012
During fetal life, the ductus arteriosus is a normal and essential structure that connects the pulmonary artery to the distal aortic arch, permitting right ventricular ejection into the aorta. After birth, with commencement of pulmonary blood flow and a 2-ventricle circulation, a variety of physiological and biochemical signals normally result ...
Bhatt Mayoor - - 2012
The effect of patent ductus arteriosus (PDA) treatment with cyclooxygenase (COX) inhibitors (indomethacin [INDO] and ibuprofen [IBU]) on regional oxygenation requires further clarification. The authors hypothesized that both INDO and IBU reduce regional tissue oxygenation in preterm neonates with PDA but that the risk is not uniform for different tissues ...
Coceani Flavio - - 2012
Closure of the ductus arteriosus at birth is a complex phenomenon being conditioned by antenatal events and progressing in preprogrammed steps. Functional at first, narrowing of the vessel is determined by 2 overlapping processes-removal of the prostaglandin E(2)-based relaxation sustaining prenatal patency and activation of a constrictor mechanism by the ...
Clyman Ronald I RI Department of Pediatrics, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94143, USA. - - 2012
Although a moderate-sized patent ductus arteriosus (PDA) needs to be closed by the time a child is 1-2 years old, there is great uncertainty about whether it needs to be closed during the neonatal period. Although 95% of neonatologists believe that a moderate-sized PDA should be closed if it persists ...
Berman Jay M - - 2012
This case study describes the first reported vaginal delivery following radiofrequency ablation (RFA) of fibroids. The subject was among a cohort of women seeking treatment for symptomatic fibroids. She was enrolled in a clinical trial studying outcomes of laparoscopic, ultrasound-guided RFA of symptomatic fibroids. A 38-year-old, G4P3, female was diagnosed ...
Kim Joon Sik - - 2012
Patent ductus arteriosus (PDA) is a significant cause of morbidity and mortality in preterm infants. Measurement of plasma B-type natriuretic peptide (BNP) has been reported to be a useful bedside screening tool for the presence of hemodynamically significant PDA (hsPDA) in neonates. This study was conducted to investigate the usefulness ...
Vida Gabriella - - 2012
Background:  The study was undertaken to compare the effects of vaginal delivery and cesarean section on the l-arginine-NO system by measuring levels of l-arginine, an endogenous nitric oxide synthase antagonist asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA) levels in the cord blood and postnatally. Methods:  Plasma samples were obtained from ...
Mercanti Isabelle - - 2012
The patency of the ductus arteriosus has ever been considered as a pathological situation in preterm infants and one likely cause of mortality and morbidity, including broncho-pulmonary dysplasia, necrotizing enterocolitis, intraventricular haemorrhage, retinopathy of prematurity. The incidence of patent ductus arteriosus is inversely proportional to gestational age and infants with ...
Hanna Nazeeh - - 2012
Preterm labor and birth continue to pose a significant challenge to physicians in the obstetrics and neonatal fields. Until specific and effective therapeutic treatments are developed to prevent preterm labor, the best means of reducing preterm birth rate is early detection and diagnosis. However, current approaches to predict preterm labor ...
Giubilini Alberto - - 2012
Abortion is largely accepted even for reasons that do not have anything to do with the fetus' health. By showing that (1) both fetuses and newborns do not have the same moral status as actual persons, (2) the fact that both are potential persons is morally irrelevant and (3) adoption ...
Vidaeff Alex C - - 2012
We sought to determine if second-trimester amniotic fluid thrombin-antithrombin (TAT) complexes concentration correlates with subsequent preterm birth. A cohort of 550 women with singleton nonanomalous pregnancies undergoing second-trimester genetic amniocentesis was followed up to delivery and analyzed as a nested case-control study. Cases of preterm birth (n = 52) were ...
Shorten Allison - - 2012
Introduction: The recent National Institutes of Health consensus conference on vaginal birth after cesarean (VBAC) recommended a focus on strategies that increase women's opportunities to make informed choices about VBAC. This study aimed to expand knowledge of women's experiences of planned VBAC by focusing on postnatal experiences of women who ...
Strathearn Lane L Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA. - - 2012
Oxytocin is a neuropeptide associated with social affiliation and maternal caregiving. However, its effects appear to be moderated by various contextual factors and stable individual characteristics. The purpose of this study was to investigate the relationship of self-reported state and trait measures (such as temperament, mood and affect) with peripheral ...
Scott-Joynt Michael - - 2012
The more vulnerable a person, of whatever age, therefore, the more there must be a presumption in favour of life; and care must be offered with particular respect and dignity, and in the best interests of the infant her/himself, not in those of others. The principles, that guide Christians in ...
Winrow Benjamin - - 2012
For a multitude of eminently modifiable reasons, death rates for pregnant women and girls and their newborn infants in poorly resourced countries remain unacceptably high. The concomitant high morbidity rates compound the situation. The rights of these vulnerable individuals are incompletely protected by existing United Nations human rights conventions, which ...
Stein Werner - - 2012
Abstract Objective: To analyze the relationship of the time interval between two deliveries, done by one obstetric team, on the delivery mode of the subsequent birth; to define the length of this interval; and to evaluate this time interval as a risk factor for increased perinatal mortality in a population-based ...
Akinsipe D Claudia - - 2012
To evaluate the effect of implementing hospital policies aimed at reducing elective labor induction and increasing spontaneous labor rates. PubMed, CINAHL, Cochrane Database of Systematic Reviews, and Dissertation Abstracts International. Observational studies published from 2000 to 2010 were the only original studies from the past 20 years that met the ...
Jefferson Kimberly K - - 2012
Preterm birth is the leading cause of infant morbidity and mortality. Very preterm births, those occurring before 32 completed weeks of gestation, are associated with the greatest risks. The leading cause of very preterm birth is intrauterine infection, which can lead to an inflammatory response that triggers labor or preterm ...
Tarannum Fouzia - - 2012
Background: Periodontal infections, which serve as a reservoir of inflammatory mediators such prostaglandin E 2 (PGE 2 ), may pose a threat to the fetal-placental unit and cause preterm delivery. Aim: This study was conducted to estimate the PGE 2 levels in gingival crevicular fluid (GCF) and to explore the ...
Oladapo Olufemi T - - 2012
There is a general agreement that oxytocin given either through the intramuscular or intravenous route is effective in reducing postpartum blood loss. However, it is unclear whether the subtle differences between the mode of action of these routes have any effect on maternal and infant outcomes. To determine the comparative ...
Spatz Diane L - - 2011
Infant admission to the Neonatal Intensive Care Unit requires that the family receives the scientific rationale for the importance of providing human milk for their child. The initiation and maintenance of maternal milk supply must be a priority. Understanding variation in milk composition is crucial so that the infant receives ...
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