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Hartert Tina V TV Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-8300, USA. - - 2010
The 'attack rate' of asthma following viral lower respiratory tract infections (LRTI) is about 3-4 fold higher than that of the general population; however, the majority of children who develop viral LRTI during infancy do not develop asthma, and asthma incidence has been observed to continuously decrease with age. Thus, ...
Bueso A - - 2010
Risk factors for wheezing specifically during the first year of life have been studied in well-developed countries, but the information from developing countries is very scarce. There are no such studies focusing on factors derived from poverty. The aim of the present study was to determine if risk factors related ...
Visser Chantal A N - - 2010
Factors operating in the first year of life are critical in determining the onset and persistence of wheezing in preschool children. This study was designed to examine the prevalence and risk factors of wheeze in the first year of life in Dutch infants. This was a population-based survey of 13-month-old ...
Roche Marion L - - 2011
The study objective was to understand the role of traditional Awajún foods in dietary quality and the potential impacts on growth of Awajún infants and young children 0-23 months of age. Research took place in April and May of 2004, along the Cenepa River in six Awajún communities. Anthropometry estimated ...
Jajoo M - - 2010
A term neonate was born to a mother who had consumed an organophosphorus compound with suicidal intent 50 hours before delivery. At birth, the infant showed signs and symptoms of organophosphorus poisoning and was treated with atropine and pralidoxime to which she responded well. Unfortunately, the mother died despite appropriate ...
Hung Yi-Li - - 2010
Bronchopulmonary dysplasia (BPD) and very low birth weight (VLBW) are associated with increased incidences of asthma and pulmonary dysfunction in childhood. However, no studies exist which examine asthma risk factors in children who were VLBW infants and did not have BPD. To address this issue, we assessed the asthma incidence ...
Mirza Bilal - - 2010
Esophageal foreign bodies (FB) are common in adults and children. These are rarely reported in infants and neonates. A 2-day-old newborn was referred to our hospital with history of accidental intrusion of soft silicone suction catheter into the upper gastrointestinal tract (GIT). X-ray chest and abdomen confirmed the presence of ...
Cox Michael J - - 2010
Colonization of the infant gut by microorganisms over the first year of life is crucial for development of a balanced immune response. Early alterations in the gastrointestinal microbiota of neonates has been linked with subsequent development of asthma and atopy in older children. Here we describe high-resolution culture-independent analysis of ...
Campusano L - - 2010
BACKGROUND: The treatment in non-atopic young children with recurrent wheezing remains controversial. OBJECTIVE: The aim of the study was to compare the response of inhaled budesonide in atopic versus non-atopic infants/preschoolers with recurrent wheezing (more than three episodes in the last year or one episode per month in the last ...
Paul Ian M - - 2010
Like obesity, the prevalence of asthma has increased over the past several decades. Accelerated patterns of infant growth have been associated with obesity and its co-morbidities. We aimed to determine if infant weight gain pattern is associated with asthma development later in childhood. Birth weight, growth, pulmonary function, and symptom ...
Rosenbaum Paula F - - 2010
In studies worldwide, respiratory outcomes such as cough, wheeze and asthma have been consistently linked to mold exposure. Young children spend most of their time indoors and may be particularly vulnerable. We evaluated the associations between exposure to airborne fungal levels and episodes of wheezing in a cohort of 103 ...
Brunner Wendy M - - 2009
INTRODUCTION: Asthma mortality rates are based on deaths for which asthma is coded as the underlying cause on the death certificate. We conducted an asthma mortality review to evaluate this surveillance measure for Minnesota residents who were aged 55 years or older METHODS: We enlisted an expert panel to review ...
Stein Renato T - - 2009
Episodes of lower respiratory illnesses (LRIs) in the first years of life have been associated with recurrent wheeze in studies of high-risk and community-based cohorts. Respiratory syncytial virus (RSV) is an agent especially associated with severe cases of bronchiolitis affecting young infants in winter months and has a typical seasonal ...
Carroll Kecia N KN Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tenn; Division of General Pediatrics, Vanderbilt University School of Medicine, Nashville, Tenn 37232-8300, - - 2009
Infants hospitalized for bronchiolitis have a high rate of early childhood asthma. It is not known whether bronchiolitis severity correlates with the risk of early childhood asthma or with asthma-specific morbidity. We sought to determine whether a dose-response relationship exists between severity of infant bronchiolitis and both the odds of ...
Villamor Eduardo - - 2009
Epidemiologic evidence linking birth weight and asthma is inconsistent. The authors examined the association between birth weight and asthma during childhood and adult life in twins. Using prospectively collected data on 21,588 like-sexed Swedish twins of known zygosity born in 1928-1952, they first conducted a cohort study to examine the ...
Mallol Javier - - 2009
BACKGROUND: Inhaled corticosteroids are used to treat infants with troublesome asthma-like symptoms but their effect on the lung function of these young patients is controversial. MATERIAL AND METHODS: Forty-four infants with recurrent wheezing (more than 3 episodes) and family history of asthma completed this randomised, parallel, double-blind, controlled trial to ...
Chong Neto Herberto Jos? - - 2009
OBJECTIVE: To verify the possibility of extending the application of an instrument to investigate the prevalence and clinical characteristics of wheezing in infants. METHODS: A cross-sectional study conducted as part of the International Study on Wheezing in Infants (EISL, Estudio Internacional de Sibilancias en Lactantes). A questionnaire was administered to ...
Roberts John W - - 2009
The health risks to babies from pollutants in house dust may be 100 times greater than for adults. The young ingest more dust and are up to ten times more vulnerable to such exposures. House dust is the main exposure source for infants to allergens, lead, and PBDEs, as well ...
Gabriele Carmelo - - 2009
Fractional exhaled nitric oxide (FeNO) is a useful tool to diagnose and monitor eosinophilic bronchial inflammation in asthmatic children and adults. In children younger than 2 years of age FeNO has been successfully measured both with the tidal breathing and with the single breath techniques. However, there are a number ...
Terauchi Hidenori - - 2009
In this study we investigated occurrences and distribution patterns of dioxin-related compounds (DRCs) such as polybrominated dibenzo-p-dioxins/dibenzofurans (PBDD/Fs), polychlorinated dibenzo-p-dioxins/dibenzofurans (PCDD/Fs), monobromo-polychlorinated dibenzo-p-dioxins/dibenzofurans (MoBPCDD/Fs) and dioxin-like polychlorinated biphenyls (DL-PCBs) in marine surface sediments collected from the coastal waters of Hong Kong and Korea. In most sampling sites, concentrations of PCDDs ...
Breton M-C - - 2009
BACKGROUND: Thirteen studies investigating the association between asthma during pregnancy and perinatal mortality reported generally no increased risk. Most of these studies should be interpreted with caution because they were limited in terms of statistical power. A study was therefore undertaken to evaluate whether maternal asthma during pregnancy increases the ...
Duncan Joanne M - - 2008
PURPOSE OF REVIEW: This review examines recent studies of the relationships between breastfeeding and the epidemiology of allergic diseases, especially atopic dermatitis in infants and asthma in early and later childhood. RECENT FINDINGS: Results from observational birth cohort studies, case-control studies, and one cluster randomized intervention trial have generally failed ...
Smitley David - - 2008
Our objective was to characterize the rate at which ash (Fraxinus spp.) trees decline in areas adjacent to the leading edge of visible ash canopy thinning due to emerald ash borer, Agrilus planipennis Fairmaire (Coleoptera: Buprestidae). Trees in southeastern Michigan were surveyed from 2003 to 2006 for canopy thinning and ...
Wu Pingsheng - - 2008
Bronchiolitis during infancy is associated with an increased risk of childhood asthma. Whether winter viral infections cause asthma or are a manifestation of a predisposition to asthma development is unknown. To study the relationship of winter virus infection during infancy and the development of childhood asthma. We studied over 95,000 ...
Kott Kayleen S - - 2008
Cysteinyl leukotrienes promote airway inflammation, bronchoconstriction and mucus hypersecretion. Cigarette smoking and respiratory syncytial virus (RSV) bronchiolitis are known to increase urinary cysteinyl leukotriene E4 (uLTE4), the end product of the cysteinyl leukotriene biosynthetic pathway. We tested the following hypotheses: (1) Secondhand smoke (SHS) exposure increases uLTE4 in well infants ...
Lillienberg L - - 2008
Metalworking fluid (MWF) aerosols are associated with respiratory disorders including asthma and hypersensitivity pneumonitis. The aims of this study were to describe exposure to inhalable MWF aerosols and volatile compounds in machine shops, to estimate the influence of important determinants of exposure and to compare different sampling techniques for MWF ...
Lee Won Jin - - 2009
OBJECTIVES: Pesticide poisoning is a major cause of death in the world. The objective of this study was to examine the trends of pesticide poisoning deaths and their epidemiologic characteristics in South Korea. METHODS: We evaluated the age-standardized mortality rates from pesticide-related deaths (intentional self-poisoning, accidental poisoning, assault, undetermined intent ...
Cote Linda R - - 2008
Cultural variation in durations, relations, and contingencies of mother-infant person-and object-directed behaviors were examined for 121 nonmigrant Latino mother-infant dyads in South America, Latina immigrants from South America and their infants living in the United States, and European American mother-infant dyads. Nonmigrant Latina mothers and infants engaged in person-directed behaviors ...
Nowakowski Amy L - - 2008
We documented valley and channel characteristics and wood loads in 19 reaches of forested headwater mountain streams in the Bighorn National Forest of northern Wyoming. Ten of these reaches were in the Upper Tongue River watershed, which has a history of management including timber harvest, tie floating, and road construction. ...
Fernandes Rochelle - - 2008
Atopy is characterized by eosinophilic inflammation associated with recruitment of eosinophil/basophil (Eo/B) progenitors. We have previously shown that Eo/B progenitor phenotypes are altered in cord blood (CB) in infants at high risk of atopy/asthma, and respond to maternal dietary intervention during pregnancy. As respiratory tract viral infections have been shown ...
Sandilands Euan A - - 2008
To determine what effect the withdrawal of co-proxamol from the UK market has had on mortality from poisoning in Scotland. This was a retrospective, observational study of mortality relating to poisoning by single agents in Scotland for the period 2000-2006. Mortality data were obtained from the General Register Office Scotland, ...
Litonjua Augusto A - - 2008
The respective prevalences of both asthma and obesity have seen a significant rise in the past few decades. Although the association between these 2 conditions has been found in many studies from different areas around the world, the exact mechanisms for how this association arises remains unresolved. Because both asthma ...
Martínez-Navarrete Juan - - 2008
We present a 1.5-year old, 11 kg, female infant with a history of bronchial hyper-responsiveness who accidentally ingested half of a "Chinese chalk". A day later, the infant showed vomiting, cough, fever, drowsiness, and irritability and her clinical conditions progressively worsened. She was admitted to the emergency department with cough, ...
Alm Bernt - - 2008
OBJECTIVE: The use of antibiotics in infancy and subsequent changes in the intestinal bacterial flora have been discussed as risk factors for the development of asthma. However, it has been difficult to exclude the possibility that antibiotics have been given in early episodes of wheezing. As a result, there has ...
van Beijsterveldt Toos C E M - - 2008
A consistent finding from twin studies is that the environment shared by family members does not contribute to the variation in susceptibility to asthma. At the same time, it is known that environmental risk factors that are shared by family members are associated with the liability for asthma. We hypothesize ...
Just J - - 2008
BACKGROUND: Early wheezing in infants is a potential risk factor for persistence of asthma into adulthood. Moreover, a personal or familial history of atopy are risk factors associated with persistence of pre-existing wheezing during childhood. However, their relative importance remains unclear. OBJECTIVES: Firstly to determine the critical thresholds of common ...
Mansfield Lyndon E - - 2008
The combination of long-acting beta-agonist (LABA) bronchodilators with inhaled corticosteroids (ICSs) has been shown to be an extremely effective treatment for asthma. Use of LABA as monotherapy for asthma is associated with increased adverse events including exacerbations and asthma deaths. However, intensive evaluation of the combined LABA-ICS therapy provided no ...
Uzuner Nevin - - 2008
Lower respiratory tract infections are the most important factors among various causes which trigger wheezing in the first year of life. The factors associated with episodic wheezing in children with acute bronchiolitis are still subjects of research. Infections, environmental factors, immunologic mechanisms are sorted as etiologic risk factors of episodic ...
Miyake Y - - 2008
Epidemiological evidence for an effect of breastfeeding on asthma continues to be inconclusive. The present prospective study examined the relationship between breastfeeding and the risk of wheeze and asthma in Japanese infants. A birth cohort of 763 infants was followed. The first survey during pregnancy and the second survey between ...
Shamovsky Igor - - 2008
The inhibition of the hERG channel by noncardiovascular drugs is a side effect that severely impedes the development of new medications. To increase hERG selectivity of preclinical compounds, we recommend the study of nondesolvation related interactions with the intended target and hERG using a baseline lipophilicity relationship approach. While this ...
Smith L M LM - - 2008
German cockroach, Blattella germanica (L.) (Dictyoptera: Blattellidae), catch by five types of traps and modifications of each, were tested under controlled laboratory conditions. Cockroach catch differed significantly among traps. Lo-line trap caught the greatest number of cockroaches in the test arena for each size class (23% small nymphs, 39% of ...
van Hennekeler K - - 2008
The ability to monitor the abundance and diversity of tabanid flies over wide areas requires effective and low-cost surveillance methods. Such monitoring activities help to quantify the risk of transmission of pathogens by tabanids. Here we examine the effectiveness and practicality of two types of trap (canopy traps and Nzi ...
Flanagan Robert J - - 2008
Certified deaths from fatal poisoning (accidents, suicides and open verdicts) in England and Wales have declined steadily (from 3952 in 1979 to 2565 in 2004). There was also a small annual reduction in suicides in males and in females over this period. In 2004, self-poisoning accounted for 25% of suicides ...
Yang Kun - - 2008
Forest ecosystems play a significant role in maintaining climate stability at the regional and global scales as an important carbon sink. Regional forest carbon storage and its dynamic changes in the Pearl River Delta have been estimated using the continuous biomass expansion factor (BEF) method based on field measurements of ...
Bakshi Rashmi - - 2008
Histopathologic analysis of 73 cases of mycetoma occurring in western Rajasthan was done from January 2001 to December 2005. Maduromycotic mycetoma remains commonest in this region as compared to actinomycotic mycetoma, which is more common in the southern part of Rajasthan. The incidence of actinomycotic mycetoma has increased during the ...
Pamer Carol - - 2008
Our study is a cross-sectional analysis of Maryland poisoning deaths for years 2003 and 2004. We used Classification and Regression Tree (CART) methodology to classify undetermined intent Maryland poisoning deaths as either unintentional or suicidal poisonings. The predictive ability of the selected set of variables (i.e., poisoned in the home ...
Bonier Frances - - 2007
Urbanization dramatically changes the composition and diversity of biotic communities. The characteristics distinguishing species that persist in urban environments, however, are poorly understood. Here we test the hypothesis that broadly adapted organisms are better able to tolerate urbanization, using a phylogenetically controlled, global comparison of birds. We compared elevational and ...
Accordino Rosalba - - 2008
Exhaled breath condensate (EBC) is being used increasingly to sample airway fluid. EBC pH may be a biomarker of airway inflammation in asthma. In this study, we assessed the long-term reproducibility of EBC pH in asthma. We examined 31 asthmatic patients and eight healthy subjects three times over a 1-year ...
Cabana Michael D - - 2007
The hygiene hypothesis suggests that the absence of infectious exposure at a critical point in immune system development leads to a greater risk for the later development of atopic disease. As a result, it may be possible to devise strategies that can block the onset of atopic diseases such as ...
Kassa Jiri - - 2007
The neuroprotective effects of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in combination with atropine in rats poisoned with cyclosarin were studied. The cyclosarin-induced neurotoxicity was monitored using a functional observational battery at 24 h and 7 days following cyclosarin challenge. The results indicate that the ...
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