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Silveira Patrícia Pelufo PP Departamentos de Pediatria, Faculdade de Medicina-Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos, 2350, Largo Eduardo Zaccaro Faraco, 90035-903, Porto Alegre, RS, Brazil, - - 2015
Large retrospective, epidemiological studies accumulated in the late 1980s, providing increasing evidence to the deeply rooted thought that perinatal events could persistently affect the individual's functioning and health/disease patterns throughout the lifetime. Evidences of such associations can be found in the literature since the beginning of the twentieth century, but ...
Larguía A Miguel AM Division Neonatology, Hospital Materno Infantil R. Sardá, Esteban De Luca 2151, Ciudad Autónoma de Buenos Aires, Argentina, - - 2015
Over the past 10 years, there has been outstanding scientific progress related to perinatal programming and its epigenetic effects in health, and we can anticipate this trend will continue in the near future. We need to make use and apply these achievements to human neurodevelopment via prevention interventions. Based on ...
Vitale S G SG Department of Medical Surgical Specialties Gynecology and Obstetrics Section, University of Catania, Catania, Italy - - - 2014
Preterm birth (PTB) is usually defined as a delivery before 37 completed weeks or 259 days of gestation. World Health Organization estimates a worldwide incidence of PTB of 9.6%. Infants born preterm are at higher risks than infants born at term for mortality, and acute and chronic morbidity. Major causes ...
Shaw Jonathan G JG Center for Innovation to Implementation, the National Center for Posttraumatic Stress Disorder, the Women's Health Section, and the Health Economics Resource Center, Department of Veterans Affairs, Palo Alto Health Care System, Palo Alto, and the March of Dimes Center for Prematurity Research at Stanford, the Centers for Health Policy/Primary Care & Outcomes Research, the Division of General Medical Disciplines, and the Departments of Obstetrics & Gynecology and Pediatrics, Stanford University School of Medicine, Stanford, - - 2014
To evaluate the association between antenatal posttraumatic stress disorder (PTSD) and spontaneous preterm delivery. We identified antenatal PTSD status and spontaneous preterm delivery in a retrospective cohort of 16,334 deliveries covered by the Veterans Health Administration from 2000 to 2012. We divided mothers with PTSD into those with diagnoses present ...
Sherrow Tammy T Mount Royal University, School of Nursing and Midwifery, Calgary, Alberta (Ms Sherrow); Respiratory Home Care Clinic, Alberta Children's Hospital and Alberta Health Services, Calgary (Ms Dressler-Mund); Early Child Development Team, Child Development Centre, Alberta Health Services, Calgary (Ms Kowal); Perinatal Follow-up Clinic, Alberta Children's Hospital, Alberta Health Services, Calgary (Ms Dai); private practice and Alberta Health Services, Calgary (Ms Wilson); and Neonatal Transition Team, Postpartum Community Health Services, Alberta Health Services, Calgary, Canada (Ms - - 2014
Gastroesophageal reflux and gastroesophageal reflux disease symptoms are common challenges for very low-birth-weight infants (<1500 g). These symptoms frequently result in feeding difficulties and family stress. Management of symptoms across healthcare disciplines may not be based on current evidence, and inconsistency can result in confusion for families and delayed interventions. ...
Faust Saul N SN NIHR Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust and Academic Unit of Clinical & Experimental Sciences, University of Southampton, United - - 2014
The role of Clostridium difficile in causing disease in infants is unclear, and the existence of C. difficile infection (CDI) in this population is controversial. As part of the drug licensing process for new CDI therapies, a Pediatric Investigation Plan is required to define studies in infants <2 years old. ...
Nisar Yasir Bin YB Sydney School of Public Health, The University of Sydney, Sydney, New South Wales, - - 2014
The aim of the current study was to examine the impact of antenatal iron-folic acid (IFA) supplementation on perceived birth size and birthweight in Pakistan over a 5-year period from 2002 to 2006. The data source was the Pakistan Demographic and Health Survey (PDHS) 2006-2007. Information from 5692 most recent ...
Andrade E E Department of Public Health, State University of Ceará (UECE), Fortaleza-CE, Brazil - - - 2014
To assess the pre and perinatal risk factors for cerebral palsy in premature infants, comparing them with full-term infants. This was a prospective cross-sectional cohort study on 48 infants between four and eight months of life, of whom 20 were born prematurely (< 37 weeks of gestational age) and 28 ...
Syvänen Johanna J Departments of Paediatric Orthopaedic Surgery (J.S., E.K., and I.H.) and Orthopaedic Surgery (J.S.), Turku University Central Hospital, Kiinamyllynkatu 4-8, 20520 Turku, Finland. E-mail address for J. Syvänen: - - 2014
The aims of this study were to determine the prevalence of congenital lower-limb reduction defects and associated mortality, to evaluate lower-limb deficiencies by type of reduction, and to identify patterns of associated anomalies. We conducted a population-based study with use of data from the Finnish Register of Congenital Malformations and ...
Zhang Xin X School of Nursing, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China (Ms Zhang and Dr. Liu); and Department of Nursing, Hungkuang University, Taiwan, China (Dr Lee); and School of Nursing, Johns Hopkins University, Baltimore, Maryland (Ms - - 2014
This systematic review evaluates the efficacy of various early interventions on maternal emotional outcomes, mother-infant interaction, and subsequent infant outcomes during neonatal intensive care unit admission and postdischarge. Key interventions associated with outcomes in both the neonatal intensive care unit and postdischarge (ie, home) settings are summarized. A comprehensive search ...
Kuizenga-Wessel Sophie S Department of Pediatric Gastroenterology and Nutrition, Emma Children's Hospital / Academic Medical Center, Amsterdam, the - - 2014
Functional constipation (FC) often begins in the first year of life. Although standard definitions and criteria have been formulated to describe FC, these are rarely used in research and clinical practice. To systematically assess how definitions and outcome measures are defined in therapeutic randomized controlled trials (RCTs) of infants with ...
Brødsgaard Anne A Department of Paediatrics, Hvidovre Hospital, The Capital Region, University of Copenhagen, - - 2014
A letter from Aydin et al (1) on our recently published study (2), states that topical clobetasol propionate should not be routinely used in infants because of the potential local and systemic side effects. We acknowledge that our study lacks information on potential systemic side effects, such as suppression of the ...
van Gelder Mmhj M Department for Health Evidence, Radboud University Medical Center, Nijmegen, the - - 2014
To study previously identified associations between specific maternal hypertensive disorders and/or prenatal exposure to antihypertensive medication and birth defects. Case-control study. Slone Birth Defects Study, 1998-2010. A total of 5568 cases with birth defects and 7253 liveborn infants without malformations as controls. Adjusted odds ratios (aORs) for birth defects associated ...
Lundequist Aiko A Department of Psychology, Stockholm University; Department of Women's and Children's Health, Karolinska - - 2014
This aim of this study was to investigate long-term cognitive outcome in a cohort of 18-year-olds born preterm and previously assessed at the age of five-and-a-half. We tested 134 adolescents born preterm with a very low birth weight of less than <1,500g and 94 term-born controls with a comprehensive cognitive ...
Sato Hiroko H Department of Pediatrics, Yamagata University School of Medicine, Yamagata, - - 2014
Neonates have physiologically increased bilirubin production and immature bilirubin metabolism, and present hyperbilirubinemia in association with genetic and or epigenetic factors. We previously reported that maximal body weight loss (inadequate feeding) is an independent risk factor for the development of hyperbilirubinemia in breast-fed Japanese neonates, and the UGT1A1 211G>A genotype ...
Rubens Craig E CE Global Alliance to Prevent Prematurity and Stillbirth, Seattle Children's Hospital, Seattle, WA 98101, USA. - - 2014
Preterm birth is a leading cause of infant morbidity and mortality worldwide, but current interventions to prevent prematurity are largely ineffective. Preterm birth is increasingly recognized as an outcome that can result from a variety of pathological processes. Despite current research efforts, the mechanisms underlying these processes remain poorly understood ...
Cotton Mark F MF Division of Paediatric Infectious Diseases, Department of Pediatrics and Child Health, Stellenbosch University and Tygerberg Children's Hospital, Tygerberg, Cape Town, South - - 2014
Early initiation of combination antiretroviral therapy (ART) in infants below 12 weeks of age reduces morbidity and mortality. A recent report of transient HIV remission in a child beginning ART from the second day of life has focused attention on very early therapy in the first days of life. In ...
Jakubiak-Lasocka Joanna J Faculty of Environmental Engineering, Warsaw University of Technology, 20 Nowowiejska St., 00-653, Warsaw, Poland, - - 2014
Air pollution is the most important environmental health risk leading to premature mortality, respiratory and other health problems. The aim of this study was to quantify its impact on infants and children in Warsaw (Poland), following the principles of Health Impact Assessment method. Particulate matter (PM2.5 and PM10) was considered ...
Johnson Mark J MJ National Institute for Health Research, Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK; Department of Neonatal Medicine, Princess Anne Hospital, University Hospital Southampton NHS Foundation Trust, Southampton, - - 2014
Hospitalised children are at increased risk of malnutrition and preterm infants, in particular, often experience poor growth (1) This may be partly attributed to variability in nutritional care and a failure to meet nutritional targets, with the extent of nutritional deficits related to the degree of postnatal growth failure seen ...
Mallow E B EB Johns Hopkins Bloomberg School of Public Health, Risk Sciences and Public Policy Institute, Baltimore, MD, - - 2014
Objective:To assess the types and magnitudes of non-endocrine toxic risks to neonates associated with medical device-related exposures to di(2-ethylhexyl)phthalate (DEHP).Study design:Dose-response thresholds for DEHP toxicities were determined from published data, as were the magnitudes of DEHP exposures resulting from neonatal contact with polyvinyl chloride (PVC) devices. Standard methods of risk ...
Moss Jennifer L JL Department of Health Behavior, Gillings School of Global Public Health, University of North Carolina, CB 7440, Chapel Hill, NC, 27599-7440, USA, - - 2014
Retrospective studies of preconception health have demonstrated that parents' health conditions and behaviors can impact a newborn's birth outcomes and, subsequently, future health status. This study sought to examine the impact of preconception health, measured prospectively, among both mothers and fathers, on two important birth outcomes: birthweight and gestational age. ...
Hawkins Summer Sherburne SS Graduate School of Social Work, Boston College, Chestnut Hill, - - 2014
It is unclear whether the benefits of tobacco control policies extend to pregnant women and infants, especially among racial/ethnic minority and low socioeconomic populations that are at highest risk for adverse birth outcomes. To examine the associations of state cigarette taxes and the enactment of smoke-free legislation with US birth ...
Al-Wassia Heidi H Department of Pediatrics, King Abdulaziz University, Jeddah, Saudi - - 2014
Umbilical cord milking (UCM) is suggested to improve neonatal outcomes. To perform a systematic review and meta-analysis of the efficacy and safety of UCM in full-term and preterm neonates. A systematic search of MEDLINE, EMBASE, CINAHL, the Cochrane Database of Clinical Trials, the clinicaltrails.gov database, and the reference list of ...
Hussain Sultana Monira SM Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, VIC, 3004, - - 2014
Objectives: Low birth weight (LBW) and preterm birth have been associated with adverse adult outcomes including hypertension, insulin resistance, cardiovascular disease and reduced bone mass. It is unknown whether LBW and preterm birth affect the risk of osteoarthritis (OA). This study aims to examine whether LBW and preterm birth were ...
McCabe Edward R B ER March of Dimes Foundation, White Plains, New York - - 2014
Preterm birth (PTB) is a serious problem, with >450 000 neonates born prematurely in the United States every year. Beginning in 1980, the United States experienced a nearly 3-decade rise in the PTB rate, peaking in 2006 at 12.8%. PTB has declined for 7 consecutive years to 11.4% in 2013, but ...
Castro Diana D Departments of Pediatrics and Neurology and Neurotherapeutics, Division of Pediatric Neurology, University of Texas Southwestern Medical Center and Children's Medical Center Dallas, 5323 Harry Hines Blvd, Dallas, TX, 75390, - - 2014
Spinal muscular atrophy is caused by mutations in the survival motor neuron 1 (SMN1) gene, leading to the reduction of SMN protein. The loss of alpha motor neurons in the ventral horn of the spinal cord results in progressive paralysis and premature death. There is no current treatment other than ...
Shrestha Prakash Sunder PS Institute of Medicine, Tribuhvan - - 2014
The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) cohort study site in Nepal is located in the Bhaktapur municipality, 15 km east of Kathmandu, the capital city of Nepal. Bhaktapur, an ancient city famous for its traditional temples ...
Caulfield Laura E LE Center for Human Nutrition, Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, - - 2014
The overall goal of The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) cohort study is to evaluate the roles of repeated enteric infection and poor dietary intakes on the development of malnutrition, poor cognitive development, and diminished immune ...
Murray-Kolb Laura E LE The Pennsylvania State University, University - - 2014
More epidemiological data are needed on risk and protective factors for child development. In The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) cohort study, we assessed child development in a harmonious manner across 8 sites in Bangladesh, Brazil, ...
Brown Sara S Sara Brown, is an Assistant Professor, University of Nebraska Medical Center, Omaha, NE. She can be reached via e-mail at sgoomis@unmc.edu and sgoomis@gmail.com Diane Brage Hudson is an Associate Professor, University of Nebraska Medical Center, Lincoln, NE. Christie Campbell-Grossman is an Associate Professor, University of Nebraska Medical Center, Lincoln, NE. Bernice C. Yates is a Professor, University of Nebraska Medical Center, Omaha, - - 2014
To examine use of technology for delivering a health promotion intervention via text blasts in single, low-income, adolescent, minority mothers and to describe their perceptions and experiences with the intervention. A qualitative descriptive design was used for this study. Health promotion information was sent weekly in the form of text ...
Parikh Tapan T From the Rogosin Institute, New York, New York, the University of Louisville School of Medicine, Louisville, Kentucky, Georgia Regents University, Augusta, and the Veterans Affairs Outpatient Clinic, Spartanburg, South - - 2014
Antipsychotic drugs prescribed to treat psychiatric symptoms during the postpartum period are secreted into breast milk. Because breast-feeding is crucial to infant development, it is important to select a medication that poses the fewest adverse consequences. Aripiprazole, haloperidol, perphenazine, and trifluoperazine demonstrate no known developmental dangers. Olanzapine, quetiapine, and risperidone ...
Chaturvedi Anuraag A Public Health Foundation of India, 5/20 Vineet Khand, Gomti Nagar, Lucknow- 226010, U.P, India. anuraag.chaturvedi@phfi.org; - - 2014
Improved infant and young child feeding practices have the potential to improve child growth and development outcomes in India. Anganwadi Workers, the frontline government functionaries of the national nutrition supplementation programme in India, play a vital role in promoting infant and young child feeding practices in the community. The present ...
Marcellus Lenora - - 2014
Infants with neonatal abstinence syndrome and their mothers require extended support through health and social service systems. Practitioners are interested in exploring innovative approaches to caring for infants and mothers. There is now compelling evidence linking women's substance use to experiences of trauma and violence. A significant shift in the ...
Gregory Elizabeth Cw - - 2014
Data from the National Vital Statistics System. Following declines from 2000 through 2006, total, early, and late fetal mortality rates were generally flat from 2006 through 2012. Fetal mortality rates were essentially stable for non-Hispanic white (4.91 per 1,000 in 2012), non-Hispanic black (10.67), and Hispanic women (5.33) during 2006-2012. ...
Fritzell Johan J Aging Research Center (ARC), Karolinska Institutet and Stockholm University, Gävlegatan 16, SE-113 30, Stockholm, Sweden, - - 2014
We aimed to examine the cross-national and cross-temporal association between poverty and mortality, in particular differentiating the impact of absolute and relative poverty. We employed pooled cross-sectional time series analysis. Our measure of relative poverty was based upon the standard 60 % of median income. The measure of absolute, or fixed, ...
Harris W S WS 1] Sanford School of Medicine-University of South Dakota, Department of Internal Medicine, SD, USA [2] OmegaQuant, LLC, Sioux Falls, SD, USA [3] Health Diagnostics Laboratory Inc, SD, USA [4] Sanford Health Research Center, Sioux Falls, SD, - - 2014
Long-chain polyunsaturated fatty acids (LCPUFA) including docosahexaenoic acid (DHA) are essential for normal vision and neurodevelopment. DHA accretion in utero occurs primarily in the last trimester of pregnancy to support rapid growth and brain development. Premature infants, born before this process is complete, are relatively deficient in this essential fatty ...
Kelleher John J Department of Pediatrics, University of Alabama at Birmingham, Birmingham, - - 2014
Prophylactic indomethacin reduces severe intraventricular hemorrhage but may increase spontaneous intestinal perforation (SIP) in extremely low birth weight (ELBW) infants. Early feedings improve nutritional outcomes but may increase the risk of SIP. Despite their benefits, use of these therapies varies largely by physician preferences in part because of the concern ...
Smith Taylor F TF Department of Psychology and Child Development, California Polytechnic State University, San Luis Obispo, California; Department of Psychology, University of North Carolina at Greensboro, Greensboro, North - - 2014
Low birth weight is associated with increased risk for Attention-Deficit/Hyperactivity Disorder (ADHD); however, the etiological underpinnings of this relationship remain unclear. This study investigated if genetic variants in angiogenic, dopaminergic, neurotrophic, kynurenine, and cytokine-related biological pathways moderate the relationship between birth weight and ADHD symptom severity. A total of 398 ...
Boerma Ragna S RS Global Child Health Group, Emma Children's Hospital, Academic Medical Center, Amsterdam, The - - 2014
HIV exposed infants, including those who do not become infected, have higher morbidity and mortality rates than HIV unexposed infants. The underlying mechanisms of this difference are largely unknown. The objective of this study was to identify the risk factors for mortality among HIV exposed (infected as well as uninfected) ...
Sim Kathleen K Department of Medicine, Section of Paediatrics, Imperial College London, London, United - - 2014
 Necrotizing enterocolitis (NEC) is a devastating inflammatory bowel disease of premature infants speculatively associated with infection. Suspected NEC can be indistinguishable from sepsis, and in established cases an infant may die within hours of diagnosis. Present treatment is supportive. A means of pre-symptomatic diagnosis is urgently needed. We aimed to ...
Porter Travis R - - 2014
Previous research has shown exposure to air pollution increases the risk of adverse birth outcomes, although the effects of residential proximity to significant industrial point sources are less defined. The objective of the current study was to determine whether yearly reported releases from major industrial point sources are associated with ...
Entringer Sonja S Departments of - - 2014
Context: Telomere biology plays a fundamental role in genomic integrity, cellular regeneration, physiology, aging, disease risk and mortality. The initial setting of telomere length (TL) in early life has important implications for telomere maintenance and related disorders throughout the lifespan. However, little is known about the predictors of this initial ...
Marek Elizabeth E Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, - - 2014
Ethanol has been used for years in neonatal and infant liquid medications, yet the pharmacokinetics, pharmacodynamics, and safety of ethanol in this vulnerable population have not been well characterized. The purpose of this review is to raise awareness of ethanol use as an excipient in neonatal and infant medications and ...
Bork Kirsten A KA From the Institut de Recherche pour le Développement (IRD), UMI233 IRD/Université de Montpellier 1, Montpellier, France (KAB, AC, and CC); the Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD (JSR); the Africa Centre for Health and Population Studies, University of KwaZulu-Natal, Somkhele, South Africa (M-LN); the Centre Muraz, Bobo-Dioulasso, Burkina Faso (NM); the International Centre for Reproductive Health, Mombasa, Kenya (SL); the Kenyatta National Hospital and University of Nairobi, Nairobi, Kenya (GM); the University of KwaZulu-Natal, Durban, South African Republic (KN); and the WHO, Reproductive Health and Research, Geneva, Switzerland (PG and - - 2014
Refraining from breastfeeding to prevent HIV transmission has been associated with increased morbidity and mortality in HIV-exposed African infants. The objective was to assess risks of common and serious infectious morbidity by feeding mode in HIV-exposed, uninfected infants ≤6 mo of age with special attention to the issue of reverse ...
Lee Adele A Nutrition Program, Department of Public Health, Food Studies and Nutrition, Syracuse University, 426 Ostrom Avenue, Syracuse, NY, 13244, USA, - - 2014
As one of the fastest growing communities in the United States, Chinese-Americans receive relatively little research attention on their rates of breastfeeding versus formula feeding, and what factors influence that choice. This research aims to examine the influence of elders and cultural beliefs on postpartum, infant feeding, and childcare practices. ...
Stimming Madlen M Research Institute of Child Nutrition (FKE), Rheinische Friedrich-Wilhelms-University Bonn, Heinstueck 11, 44225, Dortmund, Germany, - - 2014
Fish and rapeseed oil are major sources of omega-3 polyunsaturated fatty acids (n-3 PUFA) in complementary food, but little is known about current consumption in Germany. We conducted a nationwide consumer survey to assess the consumption habits of fish and rapeseed oil and their determining factors in 985 mother-child dyads ...
Rossor Thomas T Division of Asthma, Allergy and Lung Biology, MRC Centre for Allergic Mechanisms in Asthma, King's College London, London, UK, - - 2014
Congenital central hypoventilation syndrome (CCHS) is characterised by hypoventilation most marked during sleep and is often associated with abnormalities of the autonomic nervous system. We report an infant with severe CCHS and Hirschsprung disease in whom, while awaiting genotyping, the diagnosis was facilitated by the results of a carbon dioxide ...
Nakamanya Sarah S MRC/UVRI Uganda Research Unit on AIDS , Entebbe , Uganda - - 2014
Abstract Purpose: The study investigated maternal experiences of caring for a child affected by neurological impairment after neonatal encephalopathy (NE) ("birth asphyxia") in Uganda. Methods: Between September 2011 and October 2012 small group and one-on-one in-depths interviews were conducted with mothers recruited to the ABAaNA study examining outcomes from NE ...
Custer Jason W JW 1Division of Pediatric Critical Care, Department of Pediatrics, University of Maryland, Baltimore, MD. 2Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. 3Welsh Library for the School of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. 4Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. 5Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, - - 2014
Diagnostic errors lead to preventable hospital morbidity and mortality. ICU patients may be at particularly high risk for misdiagnosis. Little is known about misdiagnosis in pediatrics, including PICU and neonatal ICU. We sought to assess diagnostic errors in PICU and neonatal ICU settings by systematic review. We searched PubMed, Embase, ...
Oncel Mehmet Yekta - - 2014
Patent ductus arteriosus (PDA) is the most common cardiac condition in preterm infants. The most commonly used drugs for this purpose are cyclooxygenase inhibitors, mainly indomethacin and ibuprofen, which block the conversion of arachidonic acid to prostaglandins. On the other hand, several adverse effects have been reported with such medications, ...
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