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Silveira Patrícia Pelufo PP Departamentos de Pediatria, Faculdade de Medicina-Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos, 2350, Largo Eduardo Zaccaro Faraco, 90035-903, Porto Alegre, RS, Brazil, - - 2015
Large retrospective, epidemiological studies accumulated in the late 1980s, providing increasing evidence to the deeply rooted thought that perinatal events could persistently affect the individual's functioning and health/disease patterns throughout the lifetime. Evidences of such associations can be found in the literature since the beginning of the twentieth century, but ...
Larguía A Miguel AM Division Neonatology, Hospital Materno Infantil R. Sardá, Esteban De Luca 2151, Ciudad Autónoma de Buenos Aires, Argentina, - - 2015
Over the past 10 years, there has been outstanding scientific progress related to perinatal programming and its epigenetic effects in health, and we can anticipate this trend will continue in the near future. We need to make use and apply these achievements to human neurodevelopment via prevention interventions. Based on ...
Castro Diana D Departments of Pediatrics and Neurology and Neurotherapeutics, Division of Pediatric Neurology, University of Texas Southwestern Medical Center and Children's Medical Center Dallas, 5323 Harry Hines Blvd, Dallas, TX, 75390, - - 2014
Spinal muscular atrophy is caused by mutations in the survival motor neuron 1 (SMN1) gene, leading to the reduction of SMN protein. The loss of alpha motor neurons in the ventral horn of the spinal cord results in progressive paralysis and premature death. There is no current treatment other than ...
Shrestha Prakash Sunder PS Institute of Medicine, Tribuhvan - - 2014
The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) cohort study site in Nepal is located in the Bhaktapur municipality, 15 km east of Kathmandu, the capital city of Nepal. Bhaktapur, an ancient city famous for its traditional temples ...
Caulfield Laura E LE Center for Human Nutrition, Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, - - 2014
The overall goal of The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) cohort study is to evaluate the roles of repeated enteric infection and poor dietary intakes on the development of malnutrition, poor cognitive development, and diminished immune ...
Murray-Kolb Laura E LE The Pennsylvania State University, University - - 2014
More epidemiological data are needed on risk and protective factors for child development. In The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) cohort study, we assessed child development in a harmonious manner across 8 sites in Bangladesh, Brazil, ...
Brown Sara S Sara Brown, is an Assistant Professor, University of Nebraska Medical Center, Omaha, NE. She can be reached via e-mail at sgoomis@unmc.edu and sgoomis@gmail.com Diane Brage Hudson is an Associate Professor, University of Nebraska Medical Center, Lincoln, NE. Christie Campbell-Grossman is an Associate Professor, University of Nebraska Medical Center, Lincoln, NE. Bernice C. Yates is a Professor, University of Nebraska Medical Center, Omaha, - - 2014
To examine use of technology for delivering a health promotion intervention via text blasts in single, low-income, adolescent, minority mothers and to describe their perceptions and experiences with the intervention. A qualitative descriptive design was used for this study. Health promotion information was sent weekly in the form of text ...
Entringer Sonja S Departments of - - 2014
Context: Telomere biology plays a fundamental role in genomic integrity, cellular regeneration, physiology, aging, disease risk and mortality. The initial setting of telomere length (TL) in early life has important implications for telomere maintenance and related disorders throughout the lifespan. However, little is known about the predictors of this initial ...
Stimming Madlen M Research Institute of Child Nutrition (FKE), Rheinische Friedrich-Wilhelms-University Bonn, Heinstueck 11, 44225, Dortmund, Germany, - - 2014
Fish and rapeseed oil are major sources of omega-3 polyunsaturated fatty acids (n-3 PUFA) in complementary food, but little is known about current consumption in Germany. We conducted a nationwide consumer survey to assess the consumption habits of fish and rapeseed oil and their determining factors in 985 mother-child dyads ...
Rossor Thomas T Division of Asthma, Allergy and Lung Biology, MRC Centre for Allergic Mechanisms in Asthma, King's College London, London, UK, - - 2014
Congenital central hypoventilation syndrome (CCHS) is characterised by hypoventilation most marked during sleep and is often associated with abnormalities of the autonomic nervous system. We report an infant with severe CCHS and Hirschsprung disease in whom, while awaiting genotyping, the diagnosis was facilitated by the results of a carbon dioxide ...
Nakamanya Sarah S MRC/UVRI Uganda Research Unit on AIDS , Entebbe , Uganda - - 2014
Abstract Purpose: The study investigated maternal experiences of caring for a child affected by neurological impairment after neonatal encephalopathy (NE) ("birth asphyxia") in Uganda. Methods: Between September 2011 and October 2012 small group and one-on-one in-depths interviews were conducted with mothers recruited to the ABAaNA study examining outcomes from NE ...
Custer Jason W JW 1Division of Pediatric Critical Care, Department of Pediatrics, University of Maryland, Baltimore, MD. 2Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. 3Welsh Library for the School of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. 4Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. 5Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, - - 2014
Diagnostic errors lead to preventable hospital morbidity and mortality. ICU patients may be at particularly high risk for misdiagnosis. Little is known about misdiagnosis in pediatrics, including PICU and neonatal ICU. We sought to assess diagnostic errors in PICU and neonatal ICU settings by systematic review. We searched PubMed, Embase, ...
Oncel Mehmet Yekta - - 2014
Patent ductus arteriosus (PDA) is the most common cardiac condition in preterm infants. The most commonly used drugs for this purpose are cyclooxygenase inhibitors, mainly indomethacin and ibuprofen, which block the conversion of arachidonic acid to prostaglandins. On the other hand, several adverse effects have been reported with such medications, ...
Psaila Kim K CHoRUS Project, Family and Community Health Research Group, School of Nursing and Midwifery, University of Western Sydney, College of Health and Science, Locked Bag 1797, Penrith South DC, NSW, Australia, - - 2014
Gastro-oesophageal reflux (GOR) is commonly diagnosed in the neonatal population (DiPietro 1994), and generally causes few or no symptoms (Vandenplas 2009). Conversely, gastro-oesophageal reflux disease (GORD) refers to GOR that causes troublesome symptoms with or without complications such as damage to the oesophagus (Vandenplas 2009). Currently there is no evidence ...
Howell Elizabeth A EA Department of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai, New York, New York2Department of Obstetrics, Gynecology, and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, New - - 2014
In an effort to improve the quality of care, several obstetric-specific quality measures are now monitored and publicly reported. The extent to which these measures are associated with maternal and neonatal morbidity is not known. To examine whether 2 Joint Commission obstetric quality indicators are associated with maternal and neonatal ...
Gardner Marcia - - 2014
To describe maternal caregiving and related strategies used by first-time mothers of young infants with complex health conditions (CHC) in the first 6 months after discharge. Grounded theory. Data were collected in participants' homes in the Northeast United States. Eight first-time mothers of infants age 6 months or younger with ...
Krilov Leonard R - - 2014
Infection with respiratory syncytial virus (RSV) is common among young children insured through Medicaid in the United States. Complete and timely dosing with palivizumab is associated with lower risk of RSV-related hospitalizations, but up to 60% of infants who receive palivizumab in Medicaid population do not receive full prophylaxis. The ...
Galland Barbara C - - 2014
Interventions to prevent sudden unexpected death in infancy (SUDI) have generally been population wide interventions instituted after case-control studies identified specific childcare practices associated with sudden death. While successful overall, in New Zealand (NZ), the rates are still relatively high by international comparison. This study aims to describe childcare practices ...
Okada Tomoo T 1] Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo, Japan [2] Department of Nutrition and Life Science, Kanagawa Institute of Technology, Kanagawa, - - 2014
The concept of the developmental origins of health and disease (DOHaD) is based on studies by Barker and colleagues. They proposed a hypothesis that undernutrition in utero permanently changes the body's structure, function and metabolism in ways that lead to atherosclerosis and insulin resistance in later life. In addition, profound ...
Rechtman Lauren R LR Department of Pediatrics, George Washington University School of Medicine and Health Sciences, Washington, District of - - 2014
Sleeping on sofas increases the risk of sudden infant death syndrome and other sleep-related deaths. We sought to describe factors associated with infant deaths on sofas. We analyzed data for infant deaths on sofas from 24 states in 2004 to 2012 in the National Center for the Review and Prevention ...
Poston Lucilla L Division of Women's Health, King's College London, London, UK. - - 2014
The increased prevalence of obesity has led to major health care issues in obstetric practice. Nevertheless, despite a major international effort, there is little evidence for interventions which can improve clinical outcome. Two reports from the LIMIT randomised controlled trial of more than 2,000 overweight and obese women, recently reported ...
Gschließer Andreas A Department of Ophthalmology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, - - 2014
The objective of this study was to evaluate the correlation between twin-twin transfusion syndrome (TTTS) and the development of retinopathy of prematurity (ROP) in premature infants. Fifty-one infants who were less than 32 postmenstrual gestational weeks at birth or with a birth weight less than 1,501grams were included in this ...
Tsimis M M Johns Hopkins University School of Medicine, Department of Gynecology and Obstetrics Division of Maternal--Fetal Medicine, Integrated Research Center for Fetal Medicine, Irina Burd, Baltimore, - - 2014
The study of preterm labor and prematurity, as with any medical science, has undergone a major transformation in its approach from an inevitable part of obstetrics with few answers to one in which science has led to knowledge and clinical intervention. Despite these advancements, understanding of preterm labor and prevention ...
Chen Li L Neurology Department, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, - - 2014
To analyze in detail the clinical phenomenology of paroxysmal non-epileptic events (PNEEs) in infants and toddlers. We studied all children ≤ 2 years old age who were diagnosed with PNEEs based on video-electroencephalographic (VEEG) recordings. We analyzed the following four clinical domains of each clinical event: motor manifestations (body/limb jerking, ...
Hoppenbrouwers Toke T Division of Neonatal Medicine, University of Southern California, Los Angeles, CA, USA - - 2014
Working hypothesis: benign febrile seizures seen in 7% of infants before 6 months play a role in the terminal pathway in a subset of sudden infant death syndrome victims. Supporting evidence: (1) lack of 5-hydroxitryptamine, one consistent finding in sudden infant death syndrome that Kinney et al coined a developmental ...
Arnold Cody C Department of Pediatrics, Center for Clinical Research & Evidence-Based Medicine, University of Texas Health Science Center at Houston Medical School, Houston, TX. Electronic address: - - 2014
Phototherapy is assumed to be both effective and safe for extremely low-birth-weight infants. Our objective was to critically assess the relevant evidence from randomized trials. In the decades-old Collaborative Phototherapy Trial, phototherapy reduced serum bilirubin but not neurodevelopmental impairments. In the recent and larger Neonatal Network Trial, aggressive phototherapy compared ...
Callaghan Bridget L BL Department of Psychology, Columbia University, New York City, NY, - - 2014
Early-life caregiving shapes the architecture and function of the developing brain. The fact that the infant-caregiver relationship is critically important for infant functioning across all altricial species, and that the anatomical circuits supporting emotional functioning are highly preserved across different species, suggests that the results of studies examining the role ...
Lim David W DW Department of Surgery, University of Alberta, Edmonton, Alberta, - - 2014
Short bowel syndrome (SBS) is a growing problem in the human neonatal population. In infants, SBS is the leading cause of intestinal failure, the state of being unable to absorb sufficient nutrients for growth and development. Neonates with SBS are dependent on long-term parenteral nutrition therapy, but many succumb to ...
Morgan Catherine - - 2014
BackgroundCerebral palsy is the most common physical disability of childhood and early detection is possible using evidence based assessments. Systematic reviews indicate early intervention trials rarely demonstrate efficacy for improving motor outcomes but environmental enrichment interventions appear promising. This study is built on a previous pilot study and has been ...
Hines Monique Avril MA Cerebral Palsy Alliance, Research Institute, PO Box 560, Darlinghurst, 1300 - - 2014
Abstract Objective To systematically review meta-analyses (MAs) and randomised controlled trials (RCTs) of interventions for infants at risk of cerebral palsy (CP) to determine if consensus exists in study end-points. Methods MAs within the "Neonatal" and "Pregnancy and Childbirth" Review Groups in Cochrane Database of Systematic Reviews (to June 2011) ...
Albuquerque Plínio Luna de PL Post-Graduate Programme in Child and Adolescent Health - - 2014
Abstract Objective: To assess, through a systematic review, the ability of Alberta Infant Motor Scale (AIMS) to diagnose delayed motor development in preterm infants. Methods: Systematic searches identified five studies meeting inclusion criteria. These studies were evaluated in terms of: participants' characteristics, main results and risk of bias. The risk ...
Carmody J Bryan JB Department of Pediatrics, Division of Nephrology, Eastern Virginia Medical School, Norfolk, Virginia; - - 2014
AKI is associated with both increased short-term morbidity and mortality and greater long-term risk for CKD. This study determined the prevalence of AKI among very low birth weight infants using a modern study definition, evaluated the frequency of AKI diagnosis reporting in the discharge summary, and determined whether infants were ...
McLachlan Helen L - - 2014
Breastfeeding is associated with significant positive health outcomes for mothers and infants. However, despite recommendations from the World Health Organization, exclusive breastfeeding for six months is uncommon. Increased breastfeeding support early in the postpartum period may be effective in improving breastfeeding maintenance. This trial will evaluate two community-based interventions to ...
Allen Kimberly A KA University of Washington School of Health Sciences, - - 2014
Abusive head trauma in infants occurs in 24.6 to 39.8 per 100,000 infants in developed countries. Abusive head trauma refers to any type of intentional head trauma an infant sustains, as a result of an injury to the skull or intracranial contents from a blunt force and/or violent shaking. The ...
Bergholz Robert R Department and Clinics of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany. Electronic address: - - 2014
Comparison of the outcome of newborns with simple (sGS) and complex gastroschisis (cGS: gastroschisis with atresia, necrosis, perforation or volvulus). We conducted a systematic database search, quality assessment and meta-analyzed relevant articles which evaluated the mortality and morbidity of newborns with cGS versus sGS. Risk ratios (RR) with 95% confidence ...
Dinis-Oliveira Ricardo Jorge RJ Department of Legal Medicine and Forensic Sciences, Faculty of Medicine, University of Porto, Porto, Portugal; IINFACTS - Institute of Research and Advanced Training in Health Sciences and Technologies, Department of Sciences, Advanced Institute of Health Sciences - North (ISCS-N), CESPU, CRL, Gandra, Portugal; REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal; Center of Forensic Sciences (CENCIFOR), Portugal; CBMA - Centre of Molecular and Environmental Biology, Department of Biology, University of Minho, Braga, Portugal. Electronic address: - - 2014
This manuscript highlights and critically analyses clinical and forensic signs related to chemical burns. Signs that may lead to suspicion of a particular chemical are thoroughly discussed regarding its underlying mechanisms. Burns due to sulfuric, hydrofluoric, nitric, hydrochloric (muriatic) and acetic (including derivatives) acids, hydrogen sulphide, sodium (caustic soda) and ...
Fanos Vassilios V Neonatal Intensive Care Unit, Puericulture Institute and Neonatal Section, Azienda Ospedaliera Universitaria, University of Cagliari , Cagliari , Italy - - 2014
Abstract Objective: Bronchopulmonary dysplasia (BPD) or chronic lung disease is one of the principal causes of mortality and morbidity in preterm infants. Early identification of infants at the greater risk of developing BPD may allow a targeted approach for reducing disease severity and complications. The trigger cause of the disease ...
Xu Jiaquan - - 2014
Data from the National Vital Statistics System, Mortality. Life expectancy at birth for the U.S. population reached a record high of 78.8 years in 2012. The age-adjusted death rate for the United States decreased 1.1% from 2011 to 2012 to a record low of 732.8 per 100,000 standard population. The ...
Reddy Pashapu Dharma PD Department of Psychiatric Social Work, National Institute of Mental Health and Neuro Sciences, Bengaluru, Karnataka, - - 2014
It has been shown that mother infant interactions are often impaired in mothers with schizophrenia. Contributory factors include psychotic symptoms, negative symptoms and surrogate parenting by others. This study describes the effectiveness of video feedback in enhancing mother-infant interaction in mothers with schizophrenia who have impaired interaction with their infant. ...
Cockshaw Wendell D WD School of Psychology and Counselling, Institute for Health and Biomedical Innovation, Queensland University of Technology , Brisbane , - - 2014
Abstract Paternal postnatal depression (PND) is now recognized as a serious and prevalent problem, associated with poorer well-being and functioning of all family members. Aspects of infant temperament, sleeping and feeding perceived by parents as problematic are associated with maternal PND, however, less is known about paternal PND. This study ...
Liu Li L The Institute for International Programs, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of Population, Family, and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, - - 2014
Trend data for causes of child death are crucial to inform priorities for improving child survival by and beyond 2015. We report child mortality by cause estimates in 2000-13, and cause-specific mortality scenarios to 2030 and 2035. We estimated the distributions of causes of child mortality separately for neonates and ...
Niemarkt Hendrik J HJ *Neonatal Intensive Care Unit, Máxima Medical Center Veldhoven, Veldhoven, the Netherlands; †Department of Pediatrics, Maastricht University Medical Center, Maastricht, the Netherlands; ‡Department of Pediatric Gastroenterology, VU University Medical Center, Amsterdam, the Netherlands; §Department of Pediatric Pulmonology, Academic Medical Center, Emma Children's Hospital, Amsterdam, the Netherlands; ‖Department of Pediatrics, VU University Medical Center, Amsterdam, the Netherlands; ¶Department of Pediatrics, Academic Medical Center, Emma Children's Hospital, Amsterdam, the Netherlands; and **Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, the - - 2014
Necrotizing enterocolitis (NEC) remains one of the most frequent gastrointestinal diseases in the neonatal intensive care unit, with a continuing unacceptable high mortality and morbidity rates. Up to 20% to 40% of infants with NEC will need surgical intervention at some point. Although the exact pathophysiology is not yet elucidated, ...
Ylijoki-Sørensen Seija S Department of Forensic Medicine, Aarhus University, Brendstrupgaardsvej 100, 8200 Aarhus N, Denmark. Electronic address: - - 2014
Exact cause and manner of death determination improves legislative safety for the individual and for society and guides aspects of national public health. In the International Classification of Diseases, codes R00-R99 are used for "symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified" designated as "ill-defined" or "with ...
Watchko Jon F JF Division of Newborn Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA. Electronic address: - - 2014
Low bilirubin kernicterus in preterm neonates, though rare, remains an unpredictable and refractory form of brain injury. Hypoalbuminemia, co-morbid CNS insult(s), infection, and inflammation are contributing causes that, in many cases, appear to interact in potentiating bilirubin neurotoxicity. Despite compulsive attention to serum bilirubin levels, and clinical and laboratory indices ...
Ahmad Shaikh Meshbahuddin SM Center for Vaccine Sciences; icddr,b; Mohakhali, Dhaka 1212. Bangladesh. Electronic address: - - 2014
In recent years, neonatal vitamin A supplementation is considered as an essential infant-survival intervention but the evidence is not conclusive. This randomized controlled clinical trial was conducted to evaluate the effect of vitamin A on immune competence in early infancy. Results would provide a mechanistic basis for understanding the effect ...
Kajeepeta Sandhya - - 2014
Preterm birth is a leading cause of perinatal morbidity and mortality worldwide, resulting in a pressing need to identify risk factors leading to effective interventions. Limited evidence suggests potential relationships between maternal sleep or vital exhaustion and preterm birth, yet the literature is generally inconclusive. We examined the relationship between ...
Saad Antonio A Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, The University of Texas Medical Branch, Galveston, - - 2014
Hemorrhage is the most common cause of maternal mortality worldwide, and represents the third most common obstetrical cause of maternal death in the United States. Although uterine atony was previously a major cause of peripartum hemorrhage, more recently, it appears that abnormal placentation is the leading etiology and the main ...
Egbe Alexander A Mount Sinai Medical Center, New York, NY, USA. Electronic address: - - 2014
Congenital malformation (CM) is a leading cause of infant mortality. We hypothesized that the current estimates of the prevalence of CM are obsolete because of the increased rate of terminating fetuses with severe CMs and the widespread use of prenatal vitamins. This population-based cross-sectional study analyzed the effect of sex ...
Reid Gregor G Lawson Health Research Institute, London, ON, Canada; Departments of Microbiology & Immunology and Surgery, The University of Western Ontario, London, ON, - - 2014
As studies uncover the breadth of microbes associated with human life, opportunities will emerge to manipulate and augment their functions in ways that improve health and longevity. From involvement in the complexities of reproduction and fetal/infant development, to delaying the onset of disease, and indeed countering many maladies, microbes offer ...
Almberg Kirsten S KS University of Illinois at Chicago, School of Public Health, Epidemiology and Biostatistics Division, 1603W. Taylor Street, Chicago, IL 60607, United States of America. Electronic address: - - 2014
Missouri is an agriculturally intensive state, primarily growing corn and soybeans with additional rice and cotton farming in some southeastern counties. Communities located in close proximity to pesticide-treated fields are known to have increased exposure to pesticides and may be at increased risk of adverse birth outcomes. The study aims ...
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