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Jain Deepak D University of Miami, Miami, - - 2014
Since Northway's original description of BPD almost 45 years ago, the clinical presentation of BPD has evolved into a disease process, which mostly involves extremely premature infants. This new form of BPD is the result of multiple antenatal and postnatal factors that can cause injury to the developing lung leading ...
Biran Valérie V Neonatal Intensive Care Unit, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris, Université Paris Diderot, Paris, France; Université Paris Diderot, Sorbonne Paris Cité, INSERM, Paris, France; PremUP Foundation, Paris, - - 2014
The prevention of neurological disabilities following preterm birth remains a major public health challenge and efforts are still needed to test the neuroprotective properties of candidate molecules. Melatonin serves as a neuroprotectant in adult models of cerebral ischemia through its potent antioxidant and anti-inflammatory effects. An increasing number of preclinical ...
Uberos J J Unidad Neonatal, Servicio de Pediatría, Hospital Clínico San Cecilio, Avenida del Doctor Oloriz, 16, 18012 Granada, Spain. Electronic address: - - 2014
To assess the effectiveness of vitamin A supplementation in very low birth weight (VLBW) infants to prevent complications of prematurity. A retrospective cohort study to determine the effectiveness of vitamin A in preventing complications of prematurity in VLBW infants. Vitamin A was delivered intramuscularly at a dose of 5000 IU, three ...
van Vliet Elvira Og EO UMC Utrecht, Department of Obstetrics and Gynaecology , WKZ, PO Box 85090, 3508 AB Utrecht , Netherlands - - 2014
Introduction: In the developed world, preterm birth is in quantity and in severity the most important issue in obstetric care. Adverse neonatal outcome is strongly related to gestational age at delivery. Since the pathophysiological mechanism of preterm birth is not yet completely unraveled, the development of successful preventive strategies is ...
Joseph Christine L M CL Department of Public Health Sciences, Henry Ford Hospital, Detroit, MI, USA; Center for Allergy, Asthma and Immunology Research, Henry Ford Hospital, Detroit, MI, - - 2014
The infant gut's ability to suppress immunologic reactions to food proteins could be influenced by levels of TGFβ in breast milk. We hypothesized that lower levels of TGFβ1 in the breast milk (BM) of mothers in the WHEALS birth cohort are associated with atopy at infant age 2-3 yrs. We used ...
Mitchell Caroline C University of Washington, Seattle, - - 2014
Among HIV-1-exposed infants, detection of viral infection at birth was increased by 39% (95% CI 19-47%) by increasing DNA input from dried blood spots into PCR. Infants with low concentrations of HIV-1 at birth may be the best target population to evaluate whether immediate antiretroviral therapy can prevent long-term infection.
Gilley Meghan M BC Children's Hospital, Department of Pediatrics, Room K4-226, Ambulatory Care Bldg, 4480 Oak St, Vancouver, BC V6H 3V4. - - 2014
With the increased rate of pertussis in children, several families have asked me about ways to protect their young infants from pertussis infection. What should I recommend to these families? Pertussis is a preventable disease that is endemic worldwide. In adults pertussis causes a mild coldlike illness followed by a ...
Murray Joanna J Department of Primary Care and Public Health, Imperial College London, , London, - - 2014
In most high-income countries palivizumab prophylaxis is considered safe, efficacious and cost-effective for preventing respiratory syncytial virus (RSV) hospital admissions among specific subgroups of infants born preterm, with chronic lung disease or with congenital heart disease. Virtually all babies acquire RSV during infancy and previously healthy babies are not eligible ...
Foolad N N Department of Dermatology, University of California at Davis School of Medicine, 3301 C Street, Suite 1400, Sacramento, CA 95816, - - 2014
The purpose of this review was to identify whether supplementation with prebiotics and/or probiotics help prevent the development or reduce the severity of atopic dermatitis in children less than three years of age. Since 1997, immunostimulatory supplements, such as prebiotics and probiotics, have been investigated. Various supplementations include probiotics (single ...
Tomlinson Mark M Department of Psychology, Stellenbosch University, Stellenbosch, South - - 2014
Progress towards MDG4 for child survival in South Africa requires effective prevention of mother-to-child transmission (PMTCT) of HIV including increasing exclusive breastfeeding, as well as a new focus on reducing neonatal deaths. This necessitates increased focus on the pregnancy and early post-natal periods, developing and scaling up appropriate models of ...
Jakaitis Brett M BM Emory University School of Medicine, Department of Pediatrics, Division of Neonatology, Atlanta, GA, United - - 2014
Necrotizing enterocolitis (NEC) is a devastating disease of prematurity with significant morbidity and mortality. Immaturity of intestinal host defenses predisposes the premature infant gut to injury. An abnormal bacterial colonization pattern with a deficiency of commensal bacteria may lead to a further breakdown of these host defense mechanisms, predisposing the ...
Rehan Virender K VK Los Angeles Biomedical Research Institute at Harbor UCLA MEDICAL CENTER, Pediatrics, Torrance, California, United States ; - - 2014
Significance: Oxygen, the main mode of support for premature infants with immature lungs, can cause toxicity by producing Radical Oxygen Species (ROS) that disrupt homeostasis, yet these same molecules were entrained to promote vertebrate lung phylogeny. By providing deeper understanding of this paradox, we propose physiologically rationale strategies to prevent ...
Bartlett Jessica Dym JD Brazelton Touchpoints Center, Division of Developmental Medicine, Boston Children's Hospital, Harvard Medical School, - - 2014
To inform efforts to prevent child neglect, we investigated a wide range of risk factors that have been largely unexamined in relation to infant neglect, the most commonly occurring form of child maltreatment. Using an ecological model of child neglect, we assessed the influence of characteristics at the level of ...
Chen An-Chyi AC *Department of Pediatrics and School of Medicine, China Medical University Hospital, Taichung †Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung ‡Department of Pediatrics and School of Chinese Medicine, China Medical University Hospital §China Medical University School of Chinese Medicine, Taichung, - - 2014
Recent reports show that the incidence of and deaths caused by necrotizing enterocolitis (NEC) in preterm very-low-birth-weight (PVLBW) infants are on the rise. Unfortunately, NEC often rapidly progresses from early signs of intestinal inflammation to extensive necrosis within a matter of hours, making treatment and secondary prevention extremely difficult to ...
van den Broek Nynke R NR Centre for Maternal and Newborn Health, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United - - 2014
Assessment of risk factors for preterm birth in a population with high incidence of preterm birth and HIV infection. Secondary analysis of data for 2,149 women included in a community based randomized placebo controlled trial for the prevention of preterm birth (APPLe trial (ISRCTN84023116) with gestational age at birth determined ...
Duse M M Department of Pediatrics, Sapienza University of Rome, Italy, Rome, - - 2014
After birth various bacterial species, mainly streptococci, colonize the oral cavity and are frequently isolated from carious lesions in children. Previous studies suggest that an earlier colonization of a child’s mouth by cariogenic organisms might be related to a higher risk of caries. The aim of this study is to ...
Walsh Paul P University of California Davis, Department of Emergency Medicine , Sacramento, CA , United States ; Kern Medical Center , Bakersfield, CA , United - - 2014
Background. Pacifier use decreases the risk of sudden infant death syndrome (SIDS). An emergency department (ED) visit may provide an opportunistic 'teachable moment' for parents. Objectives. To test the hypotheses (1) that caregivers were less familiar with the role of pacifiers in sudden infant death (SIDS) prevention than other recommendations, ...
Lawani Lucky O LO School of Postgraduate Studies, Department of Community Medicine, University of Nigeria, Enugu Campus, Enugu State, - - 2014
Global and national efforts in the 21st century are directed toward the elimination of new pediatric HIV infections through evidence-based infant feeding interventions for the prevention of mother-to-child-transmission, with patient preference, motivation, and adherence identified as key factors for success. This study assessed the challenges faced by HIV-infected parturients in ...
Neu Josef J Department of Pediatrics/Neonatology, University of Florida, Gainesville, Fla., - - 2014
Necrotizing enterocolitis (NEC) is the most common severe neonatal gastrointestinal emergency that predominantly affects premature infants. Its morbidity and mortality is similar to other severe childhood diseases such as meningitis and leukemia, and is becoming increasingly recognized as a major cause of neurodevelopmental delays. The etiology of NEC remains obscure ...
Björkenstam Charlotte C Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden ; National Board of Health and Welfare, Stockholm, - - 2014
Several studies have concluded that some deaths classified as undetermined intent are in fact suicides, and it is common in suicide research in Europe to include these deaths. Our aim was to investigate if information on background variables would be helpful in assessing if deaths classified as undetermined intent should ...
Owen Leah A LA Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, - - 2014
Retinopathy of prematurity (ROP) is a potentially blinding disorder in premature infants. The underlying pathophysiology is incompletely understood, limiting the prevention and treatment of this devastating condition. Current therapies are directed toward management of aberrant neovascularization thought to result from retinal ischemia in the developing preterm retina. The molecular mediators ...
Ghaemi Sadigheh S Departments of Pediatrics, Child Growth and Development Research Center, and Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, - - 2014
Neonatal conjunctivitis leads to several ocular consequences in the affected neonates such as blindness. Currently available therapeutic options include NaNO3, Gentamicin, Neomycin and so on, in which each of them has their own limitations. Regarding the immunologic content of colostrum and its safety and easy accessibility, we aimed to evaluate ...
Kacenelenbogen Nadine N http://orcid.org/0000-0002-8602-3574 Département de Médecine Générale, Université Libre de Bruxelles, Bruxelles, - - 2014
Analyse the parental behaviours that are recognised as influencing the health of very young children based on family structure (parents separated or not). Cross-sectional study. Free preventive medicine consultations in the French Community of Belgium. Examination of 79 701 infants aged 7-11 months as part of a free preventive medicine consultation. The ...
Pavlovski Christopher J CJ Sydney, - - 2014
This paper explores the introduction of a screening test to highlight impaired immune system status for newborn infants and its efficacy as a preventative clinical measure. Moreover, it is suggested that screening of the infantile immune system has the potential to highlight susceptibility to a range of infant and childhood ...
Lester Barry M BM Center for the Study of Children at Risk, Alpert Medical School, Brown University; Women & Infants Hospital of Rhode Island; - - 2014
There has been a long-standing interest in the assessment of the neurobehavioral integrity of the newborn infant. The NICU Network Neurobehavioral Scale (NNNS) was developed as an assessment for the at-risk infant. These are infants who are at increased risk for poor developmental outcome because of insults during prenatal development, ...
Mazumder Sarmila S Centre for Health Research and Development, Society for Applied Studies, New Delhi 110016, - - 2014
To determine the effect of implementation of the Integrated Management of Neonatal and Childhood Illness strategy on treatment seeking practices and on neonatal and infant morbidity. Cluster randomised trial. Haryana, India. 29 667 births in nine intervention clusters and 30 813 births in nine control clusters. The pre-specified outcome was the effect ...
Cung Tam Giao TG Centre for International Health, University of Bergen, Bergen, - - 2014
Stillbirths are insufficiently reported in many countries. In Nablus, reporting has recently started; little is published in Palestine on the stillbirth rate and its risk factors. To study the rate of stillbirths at Rafidia Hospital in 2010 and some of its risk factors. A retrospective cohort design. Data were collected ...
Keitel Anne A Centre for Cognitive Neuroimaging, Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, United Kingdom; Research Group 'Infant Cognition and Action', Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, - - 2014
Infants and adults frequently observe actions performed jointly by more than one person. Research in action perception, however, has focused largely on actions performed by an individual person. Here, we explore how 9- and 12-month-old infants and adults perceive a block-stacking action performed by either one agent (individual condition) or ...
Espinosa Fernandez María Gracia MG Hospital Regional Universitario de Málaga. "Grupo multidisciplinar de investigación pediátrica". Unidad de Gestión Clínica de Neonatología. Málaga. España.. - - 2014
The nutrition of very low birth weight (VLBW) infants is aimed at promoting a similar growth to that occurring in the uterus. However, in practice this is difficult to achieve and extrauterine growth restriction is frequent. The current tendency is to avoid this restriction by means of early parenteral and ...
Sánchez-Tamayo Tomás T Hospital Regional Universitario de Málaga. "Grupo multidisciplinar de investigación pediátrica". Unidad de Gestión Clínica de Neonatología. Málaga. España. Universidad de Málaga. Facultad de Medicina. Málaga. España.. - - 2014
The nutrition of very low birth weight (VLBW) infants is aimed at promoting a similar growth to that occurring in the uterus. However, in practice this is difficult to achieve and extrauterine growth restriction is frequent. The current tendency is to avoid this restriction by means of early parenteral and ...
Celebi Ali Riza Cenk AR Department of Ophthalmology, Nigde State Hospital, Nigde, - - 2014
Background The aim of this study was to identify the incidence of severe retinopathy of prematurity (ROP) requiring laser treatment and the overall incidence of ROP in extremely low birth weight (ELBW) infants, and to evaluate the associated risk factors for developing severe ROP in ELBW infants in Turkey. Material ...
Crawford Nigel W NW SAEFVIC, Murdoch Children's Research Institute (MCRI), Melbourne, Victoria, Australia; Department of General Medicine, Royal Children's Hospital (RCH), Melbourne, Victoria, Australia; Department of Paediatrics, The University of Melbourne, Melbourne, Victoria, - - 2013
Preterm infants are at increased risk of vaccine preventable diseases. An audit in 2007 identified suboptimal immunisation status of preterm infants. The aim of this study was to complete the 'audit loop', reviewing preterm infants' immunisation status at a single tertiary paediatric hospital. A retrospective follow-up immunisation audit was conducted ...
Christopher Gail G Gail Christopher is vice president-program strategy and Patrick Simpson is a program officer at the W. K. Kellogg Foundation, Battle Creek, - - 2013
In 2013, the maternal and child health community received encouraging news from the Centers for Disease Control and Prevention (CDC). After having stalled from 2000 to 2005, our nation's infant mortality rate declined 12% from 2005 through 2011, to 6.05 infant deaths per 1000 live births.(1) The CDC also reported ...
Tan Sidhartha S NorthShore University Health System, University Chicago Pritzker School of Medicine, 2650 Ridge Avenue, Evanston, IL 60201, USA. Electronic address: - - 2014
There is a certainty in malpractice cases that neurodevelopmental deficits are caused by preventable events at birth when the onset, nature, and timing of the insult in the antenatal and natal period are unknown. The biggest problem is determining timing. Electronic fetal monitoring is given excessive importance in legal cases. ...
Bouras Georgios - - 2013
Studies have shown that preterm birth significantly influences mothers' psychological health. This study aimed to identify factors associated with preterm birth and assess postnatal depression and anxiety symptoms in mothers of preterm infants (n = 75) compared to mothers who delivered at term (n = 125) in a Greek sample. ...
Makari Doris - - 2013
Palivizumab monthly injections throughout the RSV season prevent severe respiratory syncytial virus (RSV) disease in preterm infants ? 35 wGA. However, some RSV guidelines currently recommend stopping palivizumab after 3 months of age in the midst of the RSV season. This article evaluates the need for full-season dosing by reviewing ...
Romero Roberto - - 2013
Preterm birth is the leading cause of perinatal morbidity and mortality worldwide, and its prevention is an important healthcare priority. Preterm parturition is one of the 'great obstetrical syndromes' and is caused by multiple etiologies. One of the mechanisms of disease is the untimely decline in progesterone action, which can ...
Del Vecchio Michael Thomas MT Department of Pediatrics, Temple University School of Medicine, St Christopher's Hospital for Children, Philadelphia, Pennsylvania, - - 2013
The present report describes three infants receiving palivizumab prophylaxis who presented with apnea associated with respiratory syncytial virus (RSV) infection. All three were found to be RSV positive but had mild bronchiolitis courses. Even though palivizumab has been shown to be an effective prophylaxis in preventing RSV bronchiolitis hospitalizations, its ...
Larijani Faezeh Javadi FJ Department of Pediatrics, Division of Nephrology, Children Medical Center, Tehran University of Medical Sciences, Tehran, - - 2013
The most common cause of neurogenic bladder dysfunction (NBD) in newborn infants is myelomeningocele. The pathophysiology almost always involves the bladder detrusor sphincter dyssynergy (DSD), which if untreated can cause severe and irreversible damage to the upper and lower urinary tracts. Early diagnosis and adequate management of NBD is critical ...
Di Gioia Diana - - 2013
This review is aimed at describing the most recent advances in the gut microbiota composition of newborns and infants with a particular emphasis on bifidobacteria. The newborn gut microbiota is quite unstable, whereas after weaning, it becomes more stable and gets closer to the typical adult microbiota. The newborn and ...
Crowther Caroline A - - 2013
Thyrotropin-releasing hormones (TRH) added to prenatal corticosteroids has been suggested as a way to further reduce breathing problems and neonatal lung disease in infants born preterm. To assess the effects of giving prenatal TRH in addition to corticosteroids to women at risk of preterm birth for the prevention of neonatal ...
Lawn Joy E - - 2013
This article is part of a supplement jointly funded by Save the Children's Saving Newborn Lives programme through a grant from The Bill & Melinda Gates Foundation and March of Dimes Foundation and published in collaboration with the Partnership for Maternal, Newborn and Child Health and the World Health Organization ...
Ghadrshenas Anisa A aClinton Health Access Initiative, Boston, Massachusetts bThe Earth Institute, Columbia University, New York, New York cCenters for Disease Control and Prevention, Atlanta, Georgia, USA dNational Health Laboratory Services, Johannesburg, South Africa eAnn & Robert H. Lurie Children's Hospital of Chicago, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, - - 2013
Prevention-of-mother-to-child-transmission (PMTCT) programs have made it possible to achieve dramatic reductions in the rate of vertical HIV transmission. However, high attrition, particularly after delivery, has limited the impact of these interventions for HIV-exposed infants who remain at risk through the end of breastfeeding. A review of current literature on early ...
Omranikhoo Habib H Department of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran ; Department of Health Promotion, School of Health, Bushehr University of Medical Sciences, Bushehr, - - 2013
Avoidable mortality as an indicator for assessing the health system performance has caught the attention of researchers for a long time. In this study we aimed to compare the health system performance using this indicator in rural and urban areas of one of Iran's southern provinces. All deaths (29916) which ...
Järvinen Kirsi M - - 2013
The role of maternal avoidance diets in the prevention of food allergies is currently under debate. Little is known regarding the effects of such diets on human milk (HM) composition or induction of infant humoral responses. To assess the association of maternal cow's milk (CM) avoidance during breastfeeding with specific ...
Papatsonis Dimitri Nm - - 2013
In some women, an episode of preterm labour settles and does not result in immediate preterm birth. Subsequent treatment with tocolytic agents such as oxytocin receptor antagonists may then have the potential to prevent the recurrence of preterm labour, prolonging gestation, and preventing the adverse consequences of prematurity for the ...
Sania Ayesha - - 2013
Our objectives were to examine the associations of neonatal and infant mortality with preterm birth and intrauterine growth restriction (IUGR), and to estimate the partial population attributable risk per cent (pPAR%) of neonatal and infant mortality due to preterm birth and IUGR. Participants were HIV-negative pregnant women and their infants ...
Maayan-Metzger Ayala - - 2013
Objective: To evaluate the effect of duration of early breastfeeding in the delivery room on blood glucose levels among term neonates of diabetic mothers. Methods: Mothers with gestational diabetes were encouraged to breastfeed their infants immediately after birth in the delivery room. The breastfeeding duration was recorded by the midwife. ...
Sung Valerie - - 2013
IMPORTANCE Excessive infant crying is common, distressing, but without proven effective prevention or management options. Probiotics may be a promising solution. OBJECTIVE To examine whether probiotics are effective in the prevention/management of crying ("colic") in infants 3 months or younger. DATA SOURCES A systematic search of MEDLINE, EMBASE, and the ...
Aydin Mustafa - - 2013
We read with great interest the article by Barois and Tourneux (1) that evaluated the feasibility and efficacy of administering immediate ketamine analgesia, plus atrophine, to preterm newborn babies at birth, so that tracheal intubation could be carried out in the delivery room. The authors suggest that this practice is ...
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