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Results 351 - 400 of 1249
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Citak Kurt A Nese AN Department of Pediatrics, Medical Faculty of Firat University, Elazig, Turkey. - - 2008
Prolidase, a specific iminopeptidase involved in collagen turnover, is especially active in growing tissues. To investigate the relationship between cord blood prolidase activity and both birth weight and gestational age. Cord blood was collected consecutively from 50 healthy newborns (35 term, 15 preterm). Prolidase activity was measured in the samples ...
Okumura Akihisa - - 2008
This article reports the results of a study on the relationship between cord blood levels of erythropoietin and periventricular leukomalacia. Cord blood was obtained from 19 infants with gestational age between 27 and 32 weeks. Cystic periventricular leukomalacia was seen in 4 of them. Erythropoietin levels were not different between ...
Atsuko Togo - - 2008
BACKGROUND: Quantitative information about the elastic properties of the large arteries can be obtained by determination of the pressure and the pulsatile changes of arterial diameter. OBJECTIVE: To study the stiffness of major branches (common carotid artery; CCA, abdominal aorta; AA and femoral artery; FA) in newborn infants. STUDY DESIGN: ...
James Rachel J A - - 2007
Our aim was to study the feeding behavior of healthy term infants in the first week of life and determine whether this was related to cord blood leptin, ghrelin, and insulin. A total of 100 healthy bottle-fed infants were studied by weighing bottles of milk before and after feeds. Leptin, ...
Bhalala U - - 2007
OBJECTIVE: To determine Vitamin D status of mother-newborn diads at birth and of their exclusively breastfed (EBF) infants at 3 months. DESIGN: Longitudinal study. METHODS: Exclusively breastfed infants born at term with birth weight > 2.5 kg to normal, healthy mothers followed till 3 months. Serum calcium, phosphorous, heat labile ...
Takaya Junji - - 2007
Many epidemiologic studies have disclosed that restricted fetal growth has been associated with an increased risk of insulin resistance in adulthood. We studied the relationship of intracellular magnesium [Mg2+]i in cord blood platelets to adipocytokine and birth size. The subjects were 20 infants with small for gestational age (SGA) and ...
Herbstman Julie B - - 2007
Recent studies have reported blood levels of polybrominated diphenyl ethers (PBDEs) in the U.S. population. Information about neonatal levels and about the relationship to polychlorinated biphenyls (PCBs) exposures is limited. The objective was to characterize levels and determinants of fetal exposure to PBDEs and PCBs among newborns from Baltimore, Maryland. ...
Mehta Rajeev - - 2007
OBJECTIVE: Investigation of magnesium (Mg) homeostasis has re-emerged as an area of interest in preterm born neonates who are at risk for brain pathology. However, data regarding the association between the biologically active ionized form of Mg and gestational age (GA) at an early stage of life in newborn infants ...
Kelishadi Roya - - 2007
The cord blood lipid profile may be associated with lifelong changes in the metabolic functions of the individual. The aim of the present study was for the first time in Iran to assess the cord blood lipid profile of neonates, as well as some of its environmental influencing factors. The ...
Gursel Turkiz - - 2007
OBJECTIVES: Newborns are susceptible to thrombosis secondary to the immature hemostatic system and maternal and fetal complications. The contribution of activated protein C resistance (APCR) to thrombosis tendency has not yet been established. This study was conducted to investigate the effects of maternal and fetal complications on APCR levels. METHODS: ...
Cromi A - - 2007
OBJECTIVE: To determine whether a large cross-sectional area of the umbilical cord is a predictor of fetal macrosomia. METHODS: Consecutive patients of > 34 weeks' gestation, who presented for sonographic examination and who delivered within 4 weeks of the examination, were included in the study. The sonographic cross-sectional areas of ...
Falade Catherine - - 2007
OBJECTIVE: To determine the burden of congenital malaria in newborns in Nigeria. METHODS: In a prospective multi-centre study, 1875 consecutive mother-baby pairs were enrolled over a continuous 12-month period. Blood smears were prepared from mothers, neonates, placental aspirates and cord blood within 4 h of delivery. Outcome variables were patent ...
Jacobson Joseph L - - 2008
OBJECTIVES: To examine the relation of cord plasma docosahexaenoic acid (DHA) concentration to gestation length, birth size, growth, and infant visual acuity, cognitive, and motor development and the effects on growth and development associated with DHA intake from breast-feeding. STUDY DESIGN: DHA, other polyunsaturated fatty acids, and 3 environmental contaminants ...
Ostrea Enrique M EM Jr Department of Pediatrics, Hutzel Women's Hospital, the Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit, MI, USA. - - 2008
The detection of fetal exposure to environmental pesticides is important because many of the pesticides are neurotoxicants and fetal exposure to these compounds can adversely affect prenatal and subsequent neurodevelopment. The aim of this study was to determine, by the comparative analysis of infant hair, cord blood and meconium, the ...
Koklu Esad - - 2007
BACKGROUND: It was shown that oxygen-derived free radicals, and particularly the superoxide anion, are intermediaries in the formation and activation of osteoclasts. Many antioxidant defence systems depend on micronutrients or are micronutrients themselves. Oxidative stress might be related to bone indices in newborn infants. AIM: To assess the relationship between ...
Khan Rozilla S - - 2007
OBJECTIVE: To determine the significance of the Diagnosis to Delivery Interval (DDI) on perinatal outcome and maternal complications in patients with umbilical cord prolapse. METHODS: This was a case series of 44 patients identified with "Umbilical cord prolapse" during a 10-year period at the Aga Khan University Hospital. Data was ...
Masters Elizabeth T ET Columbia Center for Children's Environmental Health, Mailman School of Public Health, Columbia University, New York, NY 10032, - - 2007
Adverse postnatal health effects have been associated with compromised fetal growth, which makes it essential to understand its determinants. Significant effects of environmental pollutants on birth outcomes have been observed in our study population, and nutritional status may be an additional factor influencing fetal development and effects of environmental toxins. ...
Jedrychowski Wieslaw W Epidemiology and Preventive Medicine, Jagiellonian University, Collegium Medicum, Krakow, Poland. myjedryc@cyf-kr.edu.pl - - 2008
The purpose of the study was to assess the neurocognitive status of 6-month-old infants whose mothers were exposed to low but varying amounts of lead during pregnancy. Lead levels in the cord blood were used to assess environmental exposure and the Fagan Test of Infant Intelligence (FTII) assessed visual recognition ...
Rabe Heike H Department of Neonatology, Brighton and Sussex University Hospitals, Brighton, UK. - - 2008
The optimal timing of clamping the umbilical cord in preterm infants at birth is the subject of continuing debate. To investigate the effects of a brief delay in cord clamping on the outcome of babies born prematurely. A retrospective meta-analysis of randomised trials in preterm infants was conducted. Data were ...
Nykänen Päivi - - 2007
AIM: To study the relationship between serum cortisol and dehydroepiandrosterone sulphate (DHEAS) concentrations and death or bronchopulmonary dysplasia at 36 weeks of postmenstrual age in preterm infants. METHODS: Prospective measurement of cord, day of birth (D0) and day 4 (D4) serum cortisol and DHEAS concentrations and performance of low-dose (LD) ...
Chaparro Camila M - - 2007
OBJECTIVE: To investigate whether infant iron status, modified by umbilical cord clamping time and infant feeding mode, affected infant blood lead concentration at 6 months of age. STUDY DESIGN: Participants were a subset of women and their infants randomized to receive early (10 seconds) or delayed (2 minutes) umbilical cord ...
Palkovicova Lubica - - 2008
Dental amalgam is a mercury-based filling containing approximately 50% of metallic mercury (Hg(0)). Human placenta does not represent a real barrier to the transport of Hg(0); hence, fetal exposure occurs as a result of maternal exposure to Hg, with possible subsequent neurodevelopmental disabilities in infants. This study represents a substudy ...
López-Bermejo Abel - - 2008
Visfatin is an adipocytokine involved in insulin action and oxidative stress. The regulation of circulating concentrations in the human foetus is unknown. We studied whether, at term birth, the serum concentrations of visfatin are related to foetal size, both in the absence and in the presence of maternal smoking during ...
Altanis S - - 2007
Assessment of the umbilical cord gases at birth is an objective measurement of the neonatal condition. However, previous studies have shown that the results are unreliable in one out of four paired samples. The aim of our study was to assess the sampling of cord gases after operative deliveries. We ...
Tsukimori Kiyomi - - 2007
The aim of the study was to investigate whether inflammatory markers are associated with the occurrence of periventricular leukomalacia (PVL). Superoxide (O(2) (-)) production of neutrophils and plasma antioxidative superoxide dismutase (SOD) activity in umbilical cord blood were studied. Participants were preterm infants with early PVL (n=6; three males, three ...
Groenendaal Floris - - 2008
BACKGROUND: Spinal cord injury has been reported after perinatal asphyxia in full-term neonates. OBJECTIVES: To examine the role of excessive nitric oxide production in perinatal spinal cord injury. SUBJECTS AND METHODS: Tissue samples of 18 full-term neonates who died of hypoxic-ischemic encephalopathy were analyzed for the presence of nitrotyrosine (NT). ...
El-Beitune P - - 2007
Limited evidence is available regarding antiretroviral (ARV) safety for uninfected infants exposed to these drugs in utero. Our objective was to determine if ARV administered to pregnant women is associated with decreasing umbilical arterial pH and base excess in uninfected infants. A prospective study was conducted on 57 neonates divided ...
Akturk Aysima - - 2007
OBJECTIVE: To verify whether adrenomedullin (AM) and nitric oxide (NO) concentrations are changed in the maternal and fetal circulation in pregnancies complicated by intrauterine growth restriction (IUGR) compared to normal pregnancies, and to determine any relationship between them. METHODS: Forty-six small for gestational age (SGA) and 34 appropriate for gestational ...
Bard Harry - - 2007
AIM: To determine the levels of RBC HbSNO and HbFe(II)NO using chemiluminescence in very low birth weight infants breathing room air, during the first 2 days of life. METHOD: RBC NO values were compared to the levels obtained in cord blood at birth from infants of similar gestational age. Five ...
Shanklin D Radford - - 2007
BACKGROUND: The respiratory, metabolic and excretory functions of the placenta provide maintenance of fetuses in utero even in the presence of severe malformations that preclude postnatal survival. CASE: A 17-year-old secundigravida delivered a 1,075-g liveborn in the 30th week of gestation. The infant was severely malformed, with gastroschisis and a ...
Papinniemi Marjo - - 2007
The purpose of this study was to explore the maternal risk profile and obstetric outcome in pregnancies affected by placenta previa. Retrospective case-control study involved all women (93 [0.37%] women with diagnosed placenta previa and 24,857 unaffected controls) who gave birth to singleton infants at Kuopio University Hospital between the ...
Ozdemir U - - 2007
Leptin and zinc are involved in the regulation of appetite. Copper is a trace element regulating the functions of several cuproenzymes that are essential for life. To evaluate the relationship between zinc and copper status and the leptin system in humans, we examined whether leptin concentrations in the mother and ...
Lewis David F - - 2007
OBJECTIVE: Preterm premature rupture of membranes (PPROM) continues to be a major cause of preterm births. The objective of this study was to compare the morbidity of patients with PPROM nonvertex presentations with patients with PPROM with vertex presentations. STUDY DESIGN: A retrospective analysis of data from 74 patients with ...
Pathmaperuma A N - - 2007
OBJECTIVES: To study the correlation of maternal and cord blood insulin like growth factor (IGF)-I and -II and IGF binding protein (IGFBP)-1 levels with birth weight and maternal anthropometric indices. DESIGN: Longitudinal prospective study. SETTING: Academic Institutions and a Tertiary Care Maternity Hospital. PARTICIPANTS: Women with uncomplicated singleton pregnancy (N ...
Link Gerold - - 2007
OBJECTIVE: The present study was designed to determine the relation of umbilical venous blood flow (UmbBF) to fetal weight (FW) at different times in late pregnancy, and to assess fetal O2 supply near term. STUDY DESIGN: In 46 pregnant women, UmbBF was calculated just before delivery using the product of ...
Nykänen Päivi - - 2007
OBJECTIVE: Glucocorticoids are widely used before preterm delivery and in preterm infants may bear serious adverse effects. Better knowledge about the circulating glucocorticoid milieu after glucocorticoid treatment could improve treatment modalities. Therefore, we investigated the influence of exogenous glucocorticoids and clinical factors on serum cortisol (F) levels and circulating glucocorticoid ...
Inami Ikuhiro - - 2007
In term neonates, the adiponectin concentration is higher than it is in adults. To determine the relationship between adiponectin and early neonatal growth in a cohort study. Fifty-two neonates at term were studied. Serum adiponectin concentrations, body sizes, and skinfold thicknesses were measured at birth and at 1 mo of ...
van Rheenen Patrick - - 2007
OBJECTIVES: This study was carried out to assess whether delaying umbilical cord clamping is effective in improving the haematological status of term infants living in a malaria-endemic area, and whether this is associated with complications in infants and mothers. METHODS: We randomly assigned women delivering term babies in Mpongwe Mission ...
Goldenberg Robert L - - 2007
OBJECTIVE: Laminar necrosis, a band-like distribution of coagulative necrosis, has been reported at the choriodecidual interface of the free membranes of placentas of women with various adverse neonatal outcomes. Our goal in this study was to evaluate the frequency of an equivalent feature in the decidua basalis, diffuse decidual leukocytoclastic ...
Kugelman Amir - - 2007
The purpose of this study was to test whether delayed versus immediate cord clamping would result in higher blood pressure (BP) and hematocrit (Hct), and to assess its clinical effects on the neonatal course in premature neonates (< 35 weeks). This was a prospective, masked, randomized, controlled study. Prior to ...
Hansen-Pupp I - - 2007
BACKGROUND: Foetal inflammation is associated with an increased risk of brain damage in preterm infants whereas IGF-I is essential for cerebral development and exhibits anti-apoptotic properties. AIM: To assess levels of IGF-I and IGF binding proteins at very preterm birth and to evaluate their relationship with foetal pro-inflammation and cerebral ...
Miralles R R Department of Child Health, University of Leicester, Leicester, - - 2008
To determine the fetal cortisol response to intrauterine infection. 16s ribosomal RNA genes or the urease genes of Ureaplasma spp were identified by the polymerase chain reaction in intrauterine samples. Cord blood cortisol, interleukin 6 (IL6) and IL8 were measured in samples from 31 infants born at <32 weeks gestation. ...
Divi Rao L - - 2007
Effective reduction in maternal-fetal human immunodeficiency virus-1 (HIV-1) transmission has been achieved by administration of nucleoside reverse transcriptase inhibitors (NRTIs) during pregnancy, and although most exposed children are clinically normal at birth, mitochondrial dysfunction has been reported. To examine mitochondrial integrity on a molecular level, we evaluated mitochondrial morphology by ...
Meazza Cristina - - 2007
The relationship among circulating values of growth hormone (GH), thymulin, and zinc in 19 healthy human neonates at birth and at the 4th month of age, and in their respective mothers, was investigated. Cytofluorimetric analysis on some CD antigen markers was conducted on cord blood and peripheral blood mononuclear cells. ...
Hutton Eileen K EK Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario. - - 2007
With few exceptions, the umbilical cord of every newborn is clamped and cut at birth, yet the optimal timing for this intervention remains controversial. To compare the potential benefits and harms of late vs early cord clamping in term infants. Search of 6 electronic databases (on November 15, 2006, starting ...
Brown Lisa F LF Virginia Commonwealth University, School of Nursing, Richmond, VA; and University of Wisconsin-Madison School of Nursing, Madison, - - 2007
Adaptive maternal feeding behaviors are sensitive and responsive to the infant and support the infant's participation in feeding. Adaptive infant behaviors help the infant to participate in the feeding within developmental capacities and to interact in a positive manner with the mother. Therefore, the purpose of this study was to ...
Ultee C A - - 2008
BACKGROUND: Even mild iron deficiency and anaemia in infancy may be associated with cognitive deficits. A delay in clamping the cord improves haematocrit levels and results in greater vascular stability and less need for packed cell transfusions for anaemia in the first period after birth. Follow-up data on haemoglobin levels ...
Welin Anne-Karin - - 2007
The premature infant is at increased risk of cerebral white matter injury. Melatonin is neuroprotective in adult models of focal cerebral ischemia and attenuates ibotenate-induced white matter cysts in neonatal mice. Clinically, melatonin has been used to treat sleep disorders in children without major side effects. The aim of this ...
Shimizu T - - 2007
This study investigated the relationship between plasma levels of ghrelin and postnatal growth in preterm infants. The levels of active ghrelin in cord blood and in plasma in 25 very low birthweight (VLBW) infants were measured. The results indicate that the levels of circulating active ghrelin markedly increases after birth ...
Yimin Dai
Loss of imprinting (LOI) of insulin-like growth factor II gene (IGF2) is anepigenetic abnormality associated with human diseases. However, little is known about thecharacteristics of IGF2 imprinting in newborn cord blood cells. METHODS: A total of 923cord blood samples from term singletons and related clinical data were collected; IGF2imprinting status ...
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