Search Results
Results 251 - 300 of 1227
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Marinoni Emanuela - - 2010
The aim of this study was to investigate the interrelationship between leptin,adiponectin and resistin in the fetal and early postnatal period and the association of these hormones with anthropometric and metabolic indexes. Serum concentrations of leptin, adiponectin and resistin were measured in maternal and neonatal circulation at delivery and on ...
Mellati Ali Awsat - - 2010
BACKGROUND AND AIMS: The discovery of a role for leptin in controlling fetal and neonatal growth suggests a fetal origin of some adult chronic diseases and has stimulated research into the mechanisms of action of leptin early in life. The aim of this study was to determine umbilical cord blood ...
Nykänen Päivi - - 2010
Relative adrenocortical insufficiency is often seen in sick premature newborns. As the human fetal adrenal cortex does not express the 3β-hydroxysteroid dehydrogenase (3β-HSD) enzyme before about 23 weeks of gestation, we hypothesized that this enzymatic step may be rate limiting in cortisol synthesis in premature infants of less than 28 ...
Veleminsky Milos M - - 2010
OBJECTIVE: Parasitic diseases, particularly the congenital form of toxoplasmosis, can negatively affect the mortality and morbidity of newborns and infants. METHODS: The authors examined 152 samples of umbilical blood in 152 women who had experienced premature delivery with or without PROM. The samples were examined for the titre of antibodies ...
Cohain Judy Slome - - 2010
Research based on 182,492 births, wielding statistical power to uncover even mild negative associations, showed that both single and multiple nuchal cords at the time of delivery are not associated with adverse perinatal outcomes. Nuchal cords are associated with higher birth weights and lower cesarean section rates than births without ...
Gurkanlar Doga - - 2010
PNETs of the spinal cord are aggressive and local recurrence and/or leptomeningeal spread is common. Primary spinal PNETs are extremely rare and most cases involving the spinal cord are drop metastases from primary intracranial tumors by cerebrospinal fluid. Herewith, we present a 40-day-old infant with multilevel primary spinal PNET at ...
Airey Rebecca J - - 2010
The third stage of labour is from birth of the baby until delivery of the placenta. Clamping the umbilical cord is one component of active management of the third stage. Deferring cord clamping allows blood flow between the baby and the placenta to continue; net transfer to the baby is ...
Malin Gemma L GL Department of Obstetrics, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham. - - 2010
To evaluate the association between umbilical cord pH at birth and long term outcomes. Systematic review and meta-analysis. Medline (1966-August 2008), Embase (1980-August 2008), the Cochrane Library (2008 issue 8), and Medion, without language restrictions; reference lists of selected articles; and contact with authors. Studies in which cord pH at ...
Sommerfield D - - 2010
A 35-year-old G2P1 parturient at 32 weeks of gestation with an implanted spinal cord stimulator was admitted for urgent caesarean section. Spinal anaesthesia was performed below the spinal cord stimulator leads at the L4-5 level, and a healthy female infant was delivered. A basic description of the technology and resulting ...
Rabe H H Department of Neonatology, Brighton and Sussex University Hospitals, Brighton, UK. heike.rabe @ - - 2010
Venepuncture-related blood loss is a common cause of neonatal anemia. Currently, this is the only way to obtain hemoglobin levels. This causes distress for the infant but can also lead to the need for blood transfusions. Recently, a new technique for measuring hemoglobin levels non-invasively has been developed to reduce ...
Amarilyo G - - 2010
OBJECTIVE: Prohepcidin (Pro-Hep), synthesized in the liver, is the prohormone of hepcidin (Hep), which reduces iron absorption in the gut; its synthesis is enhanced by inflammation and is reduced during hypoxia. We aimed to study the hypothesis that infants born small for gestational age (SGA) have reduced cord blood concentrations ...
Karadeniz Leyla - - 2010
BACKGROUND: In hypoxic newborns, cardiac troponin T (cTnT) was shown to be an indicator of cardiac damage and increased levels of nonprotein-bound iron (NPBI), an indicator of increased free radical production and perinatal brain damage. OBJECTIVE: The aim of this study was to determine cord blood cTnT and NPBI levels ...
Almeida Daniela - - 2009
Acute transverse myelitis (ATM) is an inflammatory disorder that affects the spinal cord. It is characterized by signs and symptoms of neurologic dysfunction in the motor and sensory tracts of the spinal cord bilaterally, resulting in weakness, sensory loss, and autonomic dysfunction with acute or subacute onset. We report on ...
Misra D P - - 2009
GOALS: Fetal growth depends on placental growth; the fetoplacental weight ratio (FPR) is a common proxy for the balance between fetal and placental growth. Male and female infants are known to have differing vulnerabilities in fetal life, during parturition and in infancy. We hypothesized that these differences may be paralleled ...
Thomas Wolfgang - - 2010
BACKGROUND: A systemic fetal inflammatory response, reflected by chorioamnionitis with funisitis, is a risk factor for bronchopulmonary dysplasia. Clara cell secretory protein (CC10), a product of pulmonary Clara cells, has anti-inflammatory properties. Local down-regulation of CC10 has been associated with inflammatory lung disease. Increased serum levels of CC10 can indicate ...
Eifinger Frank - - 2010
Neonatal testicular infarction is a rare occurrence. We report on a newborn infant with bilateral testicular infarction. At birth, the uncut umbilical cord ran taut between the thighs making a complete loop around the genitals, compressing the testes. At the age of 6 hours, because of increasing agitation and the ...
Jahan Samsad - - 2009
To investigate gender differences, if any, in leptin concentrations from umbilical cord blood of new born infants of mothers with type 2 diabetes mellitus (DM), gestational diabetes mellitus (GDM), and Non diabetic (ND) at delivery. Serum leptin concentrations were measured in 105 newborns (53 males and 52 females in the ...
Ervasti Mari - - 2009
OBJECTIVE: Hepcidin, a small 25 amino-acid antimicrobial peptide, has a significant role in the regulation of iron homeostasis. Pro-hepcidin, an 84 amino-acid peptide, is a precursor of the active hepcidin. The main aim of this study was to examine the association of maternal serum pro-hepcidin with cord blood pro-hepcidin levels ...
Kanbe Taro - - 2009
AIM: Antenatal stress, maturation and other foetal conditions affect the postnatal cardiovascular function. Atrial- (ANP) and brain-type natriuretic peptide (BNP) play important roles in regulating extracellular fluid volume and blood pressure, which may surrogate the foetal cardiovascular condition. The aim of this study was to investigate the dependence of serum ...
Najati N - - 2009
Some studies showed increased levels ofproinflammatory cytokines like IL-6, IL-8 and TNF-alpha in the blood samples of pregnant women with PROM (Premature rupture of membranes) and their neonates. The aim of this study was to find a relationship between increased level of IL-8 and PROM, a cost benefit method for ...
Balsara Z P - - 2009
OBJECTIVE: A major factor contributing to neonatal and maternal infections is unhygienic delivery practices. This study explores the impact of clean delivery kit (CDK) use on clean delivery practices during home and facility deliveries. DESIGN: Kits were distributed from primary care facilities and mothers and birth attendants received training on ...
Stark Michael J - - 2009
OBJECTIVE: With male gender as a strong predictor of cardiovascular instability, we hypothesized that gender-specific differences in circulating carbon monoxide levels contributed to dysregulated microvascular function in preterm male infants. METHODS: Infants born at 24 to 34 weeks of gestation (N = 84) were studied in a regional tertiary neonatal ...
Jaleel Riffat - - 2009
To determine the effect of delayed umbilical cord clamping on Hb (haemoglobin) and bilirubin levels of neonates and to identify newborn babies with anaemia and refer them for treatment. This Randomized Controlled Trial was conducted in the Department of Obstetrics and Gynaecology, Unit V, Dow Medical College and Lyari General ...
Martos-Moreno Gabriel A - - 2009
OBJECTIVE: To determine the influence of gestational age and fetal growth restriction on the cord blood adipokine profile, IGF1, and ghrelin levels, and their relationship with glucose metabolism. STUDY DESIGN: One hundred and ninety newborns (99 preterm and 91 full term) were studied and, according to their anthropometry at birth, ...
Jared Heather - - 2009
Maternal periodontal infection has been associated with adverse maternal and neonatal outcomes. In utero fetal exposure to oral pathogens was also recognized as deleterious to the fetus. The objective of this study was to determine the relationship between fetal exposure to oral pathogens and neonatal intensive care unit (NICU) admission. ...
Nishimaki Shigeru - - 2009
AIM: Chronic lung disease (CLD) is a major component in the morbidity of premature infants suffering from fetal inflammatory response (FIRS). The aim of the present study was to compare the value of measuring neonatal urinary beta(2)-microglobulin (beta(2)-MG) levels with fetal blood interleukin (IL)-6 levels in premature infants at risk ...
Wright D - - 2009
OBJECTIVE: Activity has been demonstrated in promoting bone mass in infants and adults. One of the major signs of fetal activity may be the length of the umbilical cord. We hypothesized that the fetus with a shortened umbilical cord may have low bone mineralization because of decreased movement or activity. ...
Tadaki Hiromi - - 2009
As antenatal environment may influence the development of atopy-predisposing immune response, cord blood cytokine productions may be an important predictor for wheezing. We investigated cord blood cytokines in a prospective birth cohort, intensively monitored for wheezy infant outcome at 1 yr. Cord blood serum samples from 269 children were assayed ...
Mestan Karen K Division of Neonatology, Children's Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60614, USA. - - 2009
In current, neonatal practice, clinical signs of intrauterine infection (IUI) are often non-specific. From a large panel of immune biomarkers, we seek to identify cord blood markers that are most strongly associated with the fetal inflammatory response (FIR), a specific placental lesion associated with serious neonatal complications. We used multiplex ...
Zota Ami R AR Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA. - - 2009
Manganese is both an essential element and a known neurotoxicant to children. High manganese exposures have been associated with negative reproductive outcomes in animals, but few epidemiologic studies have examined the effects of human fetal manganese exposure. We studied the association between maternal and umbilical cord blood manganese levels and ...
Rao Rakesh R Department of Pediatrics, Washington University of St. Louis, St. Louis, Missouri 63110, USA. - - 2009
Neurotrophins (NTs) play important roles in brain growth and development. Cord blood (CB) brain-derived neurotrophic factor (BDNF) concentrations increase with gestational age but data regarding postnatal changes are limited. We measured BDNF concentrations after birth in 33 preterm infants <32-wk gestation. Serum was collected at birth (CB), at day 2, ...
Gveric-Ahmetasevic Snjezana - - 2009
This study used malondialdehyde (MDA) determination by HPLC and enzymatic assays for total serum peroxides and antioxidant capacity to evaluate oxidative stress in 47 healthy full-term small-for-gestational age (SGA) newborns vs 67 appropriate-for-gestational age (AGA) newborns. Blood samples were collected at delivery from umbilical cord artery and vein and from ...
Hibino Satoshi - - 2009
To determine the factors associated with high molecular weight adiponectin (HMW-ad) levels during the first year of life, the longitudinal changes in serum HMW-ad were investigated from birth to 12 mo of age. The total adiponectin levels, HMW-ad, and leptin were measured longitudinally from birth to 12 mo of age ...
Hilli Johanna - - 2009
Intrauterine exposure to SSRIs in late pregnancy can cause various serotonergic symptoms in the newborns. We associated the severity of these symptoms to neurotransmitter concentrations and genetic polymorphisms in the cytochrome P450, MAO-A and COMT enzymes. Altogether 20 children with prenatal exposure to citalopram or fluoxetine were genotyped. Infants with ...
Kim Tae Hyung - - 2009
This study examined the levels of polybrominated diphenyl ethers (PBDE) in the umbilical cord blood of infants, and investigated the relationship between PBDE concentration and thyroid hormone levels. The concentration of PBDE were measured in the cord blood samples of 108 infants collected in Cheil Woman's Hospital, Seoul, Korea, in ...
Kugelman Amir - - 2009
AIM: To evaluate the immunologic and infectious consequences of delayed versus immediate cord clamping in premature infants (<35 weeks) during the neonatal period. METHODS: This was a prospective, masked, randomized, controlled, single-center study. Prior to delivery 35 infants were randomly assigned to immediate cord clamping (ICC) at 5-10 s and ...
Corona-Rivera J Román - - 2009
Encirclement of a fetal body part by the umbilical cord with or without vascular obstruction in either the umbilical cord or the encircled fetal part is considered an umbilical cord loop (UCL). Significant disruption of the encircled fetal parts is recognized as the umbilical cord disruption sequence (UCDS). UCL around ...
Shah Shilpa - - 2009
OBJECTIVE: To evaluate the predictive value of a cord serum screen test and possible subsequent development of allergic disease in infants. DESIGN: Cohort study. SETTING: 100 pregnant women were randomly recruited for the study. METHODS: The maternal serum and the cord serum of their matched newborn were analyzed for total ...
Jefford Elaine - - 2009
BACKGROUND: No good evidence exists to support the practice of routinely checking for the nuchal cord, yet it is a common medical intervention in birth. Some evidence shows damage to the baby because the practice more frequently leads to premature cord-cutting and the vaginal examination, required by such routine checking, ...
Bendon Robert W - - 2009
This autopsy of a stillborn term infant revealed a constellation of unusual features including calcification of the chorion membrane and portions of the umbilical vascular media, extensive white matter gliosis, arthrogryposis multiplex congenita, adhesions of one eyelid to the globe, pericarditis, a miniature left foot, and a cleft palate. We ...
Mullany Luke C LC Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. - - 2009
Neonatal sepsis may stem from local umbilical cord infections. Signs of cord infection are common in low-resource settings, yet the risk of mortality subsequent to these signs has not been quantified in either developed or developing countries. We compared the risk of mortality between infants with and without signs of ...
Su Chi-Feng - - 2008
OBJECTIVE: The aim of this study was to analyze the blood gas values of umbilical cord blood in newborns of first vaginal deliveries with or without obstetric interventions. MATERIALS AND METHODS: In a prospective descriptive study conducted during the 6-month period from August 2003 through February 2004 at a university ...
Lagier Aude - - 2009
OBJECTIVE: Vocal cord paralysis is the second cause of neonatal stridor. Several surgical treatments are proposed in order to avoid tracheotomy or to decanulate patients. Laser posterior partial cordotomy is supposed to be a minimal invasive procedure. The purpose of the study is to share our experience in management of ...
Verner Marc-André - - 2009
It has been suggested that pre- and postnatal exposure to persistent organic pollutants (POPs) can promote several adverse effects in children, such as altered neurodevelopment. Epidemiologic studies to date have relied on the analysis of biological samples drawn pre- or post-natally for exposure assessment, an approach that might not capture ...
Patterson Tamula M - - 2008
OBJECTIVE: Evaluate the effect of acute intrapartum stress on umbilical cord plasma levels of cholesterol, triglyceride and dehydroepiandrosterone sulphate (DS) in term infants. METHODS: Umbilical cord plasma levels of cholesterol, triglyceride and DS were measured in 176 infants that delivered >or=37 weeks' gestation. Eighty-eight infants experienced acute intrapartum stress while ...
Aly Hany - - 2009
BACKGROUND: Vascular endothelial growth factor (VEGF) is a polypeptide growth factor that is activated by tissue hypoxia. The role of VEGF in perinatal asphyxia in human neonates is yet to be clarified. In infants who develop moderate to severe acute hypoxic ischemic encephalopathy (HIE) it is crucial to clearly understand ...
Buhimschi C S CS Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA. - - 2009
To determine the relationship between presence of amniotic fluid (AF) biomarkers characteristic of inflammation (defensins 2 and 1 and calgranulins C and A) and fetal inflammatory status at birth. Prospective observational cohort. Tertiary referral University hospital. One hundred and thirty-two consecutive mothers (gestational age, median [interquartile range]: 29.6 [24.1-33.1] weeks) ...
Sandu Kishore - - 2008
A surgeon facing the problem of a child with subglottic stenosis currently has a wide range of surgical options. Cricotracheal resection is the preferred option for grade IV and severe grade III stenoses that are clear of the vocal cords. Laryngotracheal reconstruction as a less extensive procedure is preferred for ...
Page Kristin M - - 2008
Autoimmune cytopenias are a recognized complication of hematopoietic stem cell transplant (HSCT), and are considered to be a feature of chronic graft-versus-host disease (cGVHD). We report on a cohort of very young infants (< or =3 months of age) receiving HSCT from unrelated donor umbilical cord blood for genetic disorders ...
Teksam Ozlem - - 2008
OBJECTIVE: The effects of meconium-stained amniotic fluid (MSAF) on cord blood vascular endothelial growth factor (VEGF) levels have not been explored. The aim of this study was to verify whether MSAF influences cord blood VEGF levels in healthy term neonates and we can use cord blood VEGF levels in infants ...
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