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Results 351 - 400 of 810
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Verklan M T - - 1999
Identifying variables predictive of neurobehavioural sequelae is a key objective in the study of high-risk neonates. Examination of heart rate variability (HRV) characteristics may be a finer discriminator of the neonate's response to physiologic stressors than the mean heart rate. The energy entropy of the heart beat tachogram, computed in ...
Liu H - - 1999
We treated a neonatal infant who presented with heart failure and a giant torcular dural arteriovenous fistula by staged transtorcular embolization with two guidewires, 95 platinum microcoils, and tissue glues through a needle-size craniotomy. Blood loss was minimal. The patient was stable without heart failure after a three-staged embolization. The ...
Rosenstock E G - - 1999
Naturally occurring oscillations in heart rate have long been considered to reflect the modulating influences of the autonomic nervous system. Individual reports of heart rate variability in healthy and sick neonates and infants have provided valuable information as to pathophysiological changes in autonomic cardiovascular control. It is evident that prematurity ...
Klassen L R - - 1999
Complete congenital heart block (CCHB) is a rare disease of the newborn that carries significant morbidity and mortality. It generally occurs as a result of the presence of maternal autoantibodies that are transferred to the fetus and affect the fetal heart, or it may be associated with a congenital structural ...
Wang J N - - 1999
The association of tricuspid atresia and persistent truncus arteriosus is a very rare congenital anomaly. We report a newborn with a prenatal diagnosis of tricuspid atresia, in whom associated type II persistent truncus arteriosus was found by postnatal echocardiography. The patient had mild cyanosis and developed heart failure soon after ...
Saenz R B - - 1999
Congenital heart defects are classified into two broad categories: acyanotic and cyanotic lesions. The most common acyanotic lesions are ventricular septal defect, atrial septal defect, atrioventricular canal, pulmonary stenosis, patent ductus arteriosus, aortic stenosis and coarctation of the aorta. Congestive heart failure is the primary concern in infants with acyanotic ...
Brook M M - - 1999
Endocarditis is a rare but serious complication often related to complex CHD. The incidence, particularly among smaller infants with cyanotic heart disease, seems to be increasing. The pathophysiology is related to a combination of host and bacterial factors that predispose to endothelial colonization and infection. Diagnosis, although occasionally difficult, is ...
Uzun O - - 1999
A child of a mother with maternal anti-Ro and anti-La antibodies presented antenatally with abnormal myocardial function, and was found to have a first degree heart block at birth. The extent of the abnormality in the conduction system progressed, with appearance of left bundle branch block in addition to further ...
Newton C W - - 1999
OBJECTIVE: To determine if buffered lidocaine provided a more effective nerve block in a short time than plain lidocaine for neonatal circumcision. METHODS: One hundred ninety-four newborn males were studied in a randomized trial using two dorsal penile nerve block preparations for circumcision. Ninety-two received plain lidocaine, and 102 received ...
Narchi H - - 1999
We studied the value of routine neonatal electrocardiography (ECG) in the 1st 48 hours of life to diagnose congenital heart disease in 37 neonates with Down syndrome. Twenty-four infants had no clinical evidence of congenital heart disease, had normal ECGs and normal cardiac anatomy on echocardiography. Thirteen children (35.2%) had ...
Mortola J P - - 1999
In fetuses and newborn infants heart rate variability changes in conditions of acute and chronic hypoxia; we therefore asked whether heart rate variability of infants born at high altitude differed from that of low-altitude infants. Short-term recordings (4-5 min) of inter-beat intervals were obtained in 19 infants in Lima (50 ...
Gussak I - - 1999
In clinical cardiology, deceleration-dependent QT interval shortening is considered to be an extraordinary electrocardiographic phenomenon. We present an early premature born 4-year-old African-American girl with complications related to her premature birth, developmental delay, and several episodes of cardiac arrest. An episode of severe transient bradyarrhythmia was documented on Holter monitoring. ...
Krafchik B R - - 1999
Neonatal lupus is categorized by typical clinical features and the presence of maternal auto-antibodies. Mothers are uncommonly affected with clinical disease. The major clinical manifestations in neonates are cardiac, dermatological and hepatic, with rare instances of haemolytic anaemia and thrombocytopenia. The major morbidity and mortality result from complete congenital heart ...
Narayan S M - - 1999
INTRODUCTION: Repolarization alternans (RPA) may reflect repolarization heterogeneities underlying VT, yet its temporal dynamics are poorly understood. We hypothesized that RPA occurring late, rather than early, within repolarization reflects a temporal variation in recovery that may predispose to wavefront fractionation and the initiation of reentrant VT, and that this temporal ...
Fugelseth D - - 1999
The newborn pig is currently the most used species in animal neonatal research. Valid non-invasive monitoring is important in particular for long-term survival of unsedated animals. In the unsedated newborn pig (n = 35, median age 24 h, range 7-48 h) we standardized two-dimensional Doppler echocardiography and determined the normal ...
Cnota J F - - 1999
We describe three infants <3 months of age seen consecutively with dilated cardiomyopathy who presented initially with left bundle branch block on the surface 12-lead electrocardiogram. Each infant subsequently had a poor outcome: two died and one required heart transplantation. These results suggest that the presence of left bundle branch ...
Miyagawa S - - 1998
IgG antibodies to a cleavage product of alpha-fodrin (120 kDa alpha-fodrin) have recently been identified as organ-specific autoantibodies in primary Sjögren's syndrome. In this study, we examined seroreactivity of mothers and infants with neonatal lupus erythematosus (NLE) to a recombinant NH2-terminal protein (120 kDa alpha-fodrin) of human alpha-fodrin. Serum samples ...
Burton P B - - 1998
The success of infant and neonatal heart transplantation has increased dramatically since the mid-1980s. This success is due both to improved medical and surgical techniques and better pharmacological management of rejection episodes. We report here the results of in vitro studies designed to investigate the effect of rapamycin (a macrolide ...
Mazursky J E - - 1998
To investigate developmental changes in autonomic cardiovascular reflexes in preterm infants, we used autoregressive power spectral analysis to analyze the effect of upright tilting on heart rate variability in preterm infants. Twenty-eight infants were studied in a longitudinal fashion beginning at 28-32 weeks postconceptional age (postnatal age 1-5 weeks). Each ...
Reis P M - - 1998
OBJECTIVE: The objective of this study was to describe the obstetric parameters from 219 deliveries of infants with hypoplastic left heart syndrome. STUDY DESIGN: The Pediatric Cardiovascular Surgery Database at the University of Michigan was searched, and cases of neonates with the diagnosis of hypoplastic left heart syndrome were found. ...
Bengur A R - - 1998
This article reviews the use of intraoperative echocardiography during repair of congenital heart defects. Although initial experience was generated using epicardial transducers, there has been a trend in recent years toward the use of transesophageal echocardiography (TEE) in the operating room. This has encouraged increased involvement from cardiologists and anesthesiologists. ...
Shefi O - - 1998
Thermoregulation in humans can be divided into three broad mechanisms of control, namely: shivering, sweating and vasomotor activity. Previous investigations suggested the presence of an autonomic rhythm, originating in the central nervous system, possibly related to thermal vasomotor control and directly affecting heart rate by reflex changes in cardiac sympathetic ...
Mitchell M B - - 1998
OBJECTIVES: Our objectives were to (1) review our experience with heart transplants in infants (age < 6 months), (2) delineate risk factors for 30-day mortality, and (3) compare outcomes between our early and recent experience. METHODS: Records of all infants listed for transplantation in our center before September 1996 were ...
Pickert C B - - 1998
BACKGROUND: The differentiation of severe systemic infection, such as sepsis or meningitis, from a congenital obstructive left heart abnormality presents a unique challenge to clinicians responsible for the care of such infants in the first few weeks of life. Clinical findings are very similar in the two populations. Failure to ...
Weyand M - - 1998
BACKGROUND: Until recently, newborns with medically intractable cardiac failure caused by congenital malformations were mostly doomed to death because of the severity of the disease, which precludes a palliative operation, or because of fatal deterioration before availability of a suitable donor heart. METHODS: The recently developed paracorporeal pneumatically driven Medos ...
Louthrenoo W - - 1998
An association between complete congenital heart block (CCHB) and anti-Ro/SSA antibody is well recognized but has never been reported in Thailand. We report here a 37-year-old female who was admitted because of massive epistaxis secondary to immune thrombocytopenia. She had given birth to a child with CCHB 2 years previously, ...
Fixler D E - - 1998
The purpose of this study was to determine whether there are important differences in maternal and environmental prenatal risk factors between liveborn Down syndrome infants with congenital heart defects and Down syndrome infants without heart defects. Using a case control study design, we evaluated the risk associated with maternal illness, ...
Bolz D - - 1998
Acute heart failure in the early neonatal period is rare. Normally it is due to asphyxia, severe septicaemia, a congenital heart malformation or a viral myocarditis. Kawasaki disease (KD) as a cause of an neonatal myocarditis is not an established diagnosis. KD is a vasculitis of still unknown origin occurring ...
Hehrlein F W - - 1998
Therapy for the hypoplastic left heart syndrome (HLHS) is still under debate. We report about our experience in the treatment of this cardiac malformation using heart transplantation and Norwood palliation. From 1988 to 1997 a total number of 30 infants with hypoplastic left heart underwent heart transplantation. Mean age at ...
Buchhorn R - - 1998
We report on the clinical and neurohumoral effects of adding low-dose propranolol to conventional therapy with digoxin and diuretics in 6 infants with severe congestive heart failure due to large left-to-right shunts. A significant decrease in heart failure scores and a decrease of the highly activated renin-angiotensin-1 aldosterone system by ...
Huffman L C - - 1998
Sixty 12-week-old infants participated in a laboratory study to explore the relations between temperament and cardiac vagal tone. Temperament was evaluated via laboratory observations and maternal ratings. Cardiac vagal tone, measured as the amplitude of respiratory sinus arrhythmia, was quantified from beat-to-beat heart period data collected during a resting baseline ...
Dandurand L - - 1998
Coarctation of the aorta is a congenital cardiac abnormality that can lead to congestive heart failure in early infancy or can go undetected for many years. We discuss the case of an infant who presented to our emergency department with epistaxis and was found to have this lesion based on ...
Buyon J P - - 1998
OBJECTIVES: The present study describes the demographics, mortality, morbidity and recurrence rates of autoimmune-associated congenital heart block (CHB) using information from the Research Registry for Neonatal Lupus. BACKGROUND: Isolated CHB detected at or before birth is strongly associated with maternal autoantibodies to 48-kD SSB/La, 52-kD SSA/Ro and 60-kD SSA/Ro ribonucleoproteins ...
Törö K - - 1998
Hungarian mortality rate is one of the highest in Europe. We have investigated the association between poor living standards and ischemic heart disease by a detailed geographical comparison of infant mortality in 1920-1939 and death in adults from ischemic; heart disease and other leading causes of death in 1990-1994. Ischemic ...
Sehra R - - 1998
Although commonly found on echocardiograms, persistent Eustachian valves rarely result in clinical symptoms in newborns and infants without other significant structural heart disease. Previous reports have suggested that such patients require surgical treatment. The goal of this study is to delineate better the clinical course in infants presenting with symptoms ...
Amin S B - - 1998
We report the first two documented cases of neonatal zygomycosis caused by Absidia corymbifera. A premature infant developed disseminated disease from a cutaneous site with pulmonary, gastrointestinal, and cerebral involvement. The infant died despite amphotericin B therapy and surgical debridement. The second case occurred in a full-term infant with congenital ...
Pringle D G - - 1998
Spatial disparities in the prevalence of heart disease are frequently explained in terms of adult lifestyle factors (e.g. diet, smoking, alcohol consumption, stress, exercise, etc.). However, research in recent years suggests an alternative explanation: namely, that the risk of heart disease in adult life may be influenced either by living ...
Hamersley S L - - 1998
BACKGROUND: Alterations in fetal heart rate variability and baseline may be seen with maternal administration of magnesium sulfate. In this case, a dose-related decrease in the baseline fetal heart rate was observed in association with magnesium sulfate administration. CASE: A primiparous woman was given parenteral magnesium sulfate for preterm labor. ...
Chu J J - - 1998
Low cardiac output after open heart operations in neonates and infants carries a high mortality. Delayed sternal closure may be life-saving but may prolong hospital stay and increase costs. To circumvent these issues, we shaped homograft bone and interposed it between the sternal edges to allow primary wound closure in ...
Heinle Jeffrey S. - - 1998
Surgical intervention for many patients born with congenital heart disease has become routine in the first few months of life. Early extubation after cardiac surgery in neonates and young infants is feasible for many of these patients. This approach simplifies postoperative management, eliminates some of the complications related to postoperative ...
Gurunathan S - - 1998
Random fluctuations of ventricular fibrillation (VF) affect defibrillation; in addition, the heart is more susceptible to defibrillation at a higher absolute VF voltage (AVFV). Shocks delivered at higher AVFV waveforms from a single lead of the electrocardiogram (ECG) are more effective than conventional shocks. The authors investigated a new sensing ...
Eck J B - - 1998
We describe the use of remifentanil in three infants with complex medical issues (hepatic failure, cyanotic heart disease and renal compromise). The short duration of opioid effect even after a long period of drug infusion (18 h) suggests this drug may be useful in some infants. Continued study is warranted.
Donnelly J P - - 1998
OBJECTIVE: Coronary physiology in infants with congenital heart disease remains unclear. Our objective was to better understand coronary physiology in infants with congenital heart disease. METHODS: We used positron emission tomography with nitrogen 13-labeled ammonia to measure myocardial perfusion at rest and with adenosine (142 micrograms/kg/min x 6 minutes) in ...
Möller J C - - 1998
Neonatal asphyxia is a major topic of neonatal research. However, no clear-cut physiologic parameters exist which enable an early identification of neonatal infants who are either at risk to develop brain damage or posthypoxic heart failure. Parameters indicating dysfunction of the heart and kidneys as creatinine and creatinine kinase have ...
Leslie A M - - 1998
The study of object cognition over the past 25 years has proceeded in two largely non-interacting camps. One camp has studied object-based visual attention in adults, while the other has studied the object concept in infants. We briefly review both sets of literature and distill from the adult research a ...
Rajs J - - 1997
A total of 423 medicolegal autopsies of infants under the age of 1 year were done during a 15-year period (1980-1994) at the Department of Forensic Medicine in Stockholm. Only two instances with findings of tumors occurred. One was a unilateral oligodendroglioma involving the medullary reticular formation and inferior olivary ...
Zwacka G - - 1997
Ten infants at ages from 1 to 5 months (1st and 2nd trimenon) suffering from congenital inspiratory stridor were examined, dependent on the respective severity of their stridorous phenomenons each, either clinically or/and endoscopically or/and polygraphically, for differentiation of the diagnoses and for assessment of their needs of nCPAP therapy.With ...
Santini F - - 1997
Homograft supply is limited especially for those sizes required for neonatal and infant cardiac operations. Surgically downsized homografts have been successfully used for right ventricular outflow tract reconstruction in 5 children (mean weight 6.2 kg) with evidence of good hemodynamic performance of the conduits at a mean follow-up time of ...
Joseph J T - - 1997
We present the pathology and molecular genetic analysis of an infant with congenital myotonic dystrophy. The proband/infant, born at 35 weeks' gestational age to a mother with myotonic dystrophy and 750 CTG repeats, was markedly hypotonic and had severe cardiomyopathy. She died after 16 days of life. At autopsy, skeletal ...
Ingemarsson I - - 1997
OBJECTIVE: To study the outcome after acidaemia at term birth, and the relation to gender and duration of pathological fetal heart rate changes. DESIGN: Population based study of 154 infants with umbilical artery pH < 7.05 at term birth. Neonatal outcome and the result of developmental screening at age four ...
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