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Lapillonne Alexandre A Department of Neonatal Medicine, Paris Descartes University, APHP Necker Hospital, Paris, - - 2013
The level of adherence to guidelines should be explored particularly in preterm infants for whom poor nutrition has major effects on outcomes in later life. The objective was to evaluate compliance to international guidelines for parenteral nutrition (PN) in preterm infants across neonatal intensive care units (NICUs) of four European ...
Chong Jin Ho JH Department of Neonatology, KK Women's and Children's Hospital, - - 2013
Hyperinsulinaemic hypoglycaemia in small-for-gestational age infants usually presents in the first two postnatal days. We present a preterm, small-for-gestational age infant who had hyperinsulinaemic hypoglycaemia on day 13 of life. A female twin infant weighing 1390 g was born at 32(+6) weeks of gestation. Her glycaemic profile was normal till ...
- - 2013
The nutrition societies of Germany, Austria and Switzerland are the joint editors of the 'reference values for nutrient intake'. They have revised the reference values for the intake of calcium and published them in June 2013. The reference values for the calcium intake for infants are derived from the calcium ...
Jolin-Dahel Kheira K University of Ottawa, Ottawa, ON, Canada K1H - - 2013
Background. Parenteral nutrition (PN) is an effective method of nourishing the neonate who is unable to receive full enteral feeds. Cholestasis can be a complication of PN and can lead to severe liver damage. Aim. We describe our patient population and determine risk factors for developing PN cholestasis. Methods. Retrospective ...
Svigos John J Women's and Children's Hospital, North Adelaide, SA 5006, Australia ; Ashford Hospital, Keswick, SA 5035, - - 2013
We report a baby with an unusual true umbilical cord cyst detected at 12 weeks gestation which as the pregnancy progressed became increasingly difficult to distinguish from a pseudocyst of the umbilical cord. Concern of the possibility of cord compression/cord accident led to an elective caesarean section being performed at ...
Lundström Johan N JN Monell Chemical Senses Center Philadelphia, PA, USA ; Department of Clinical Neuroscience, Karolinska Institutet Stockholm, Sweden ; Department of Psychology, University of Pennsylvania PA, - - 2013
Studies in non-human mammals have identified olfactory signals as prime mediators of mother-infant bonding and they have been linked with maternal attitudes and behavior in our own species as well. However, although the neuronal network processing infant cues has been studied for visual and auditory signals; to date, no such ...
Muenssinger Jana J fMEG Center, University of Tuebingen , Tuebingen , - - 2013
Auditory change detection is crucial for the development of the auditory system and a prerequisite for language development. In neonates, stimuli with broad spectral width like white noise (WN) elicit the highest response compared to pure tone and combined tone stimuli. In the current study we addressed for the first ...
Borjianyazdi L L Assistant Professor of Neonatology, Shahid Sadoughi University of Medical Sciences and Health Services,Yazd, - - 2013
This study was conducted to evaluate the clinical effect of Granulocyte Colony Stimulating Factor (GCSF) on prognosis of neonatal sepsis. Present study is a double- blinded randomized clinical trial, conducted on 46 preterm infants with neutropenia (Absolute Neutrophil Count (ANC) ≤ 5000 / μL) and clinical sepsis. Infants were randomly ...
Bagnell Carol A - - 2013
A window of opportunity for maternal programming of neonatal development is open in the first few days of life as a consequence of nursing. Colostrum (first milk) supports neonatal development by providing a conduit for delivery of milk-borne bioactive factors, exemplified by relaxin, from mother to offspring as proposed in ...
Goyal Neera N Division of Neonatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, - - 2013
Evidence to guide safe discharge for late preterm infants (34-36 weeks' gestation) is lacking. Previous studies have demonstrated the increased risk of neonatal readmission for these infants compared with those born at term (> or =37 weeks' gestation). The purpose of this study was to estimate the effect of length ...
Morrow Ardythe L AL Perinatal Institute, Cincinnati Children's Hospital Medical Center, Department Pediatrics, University of Cincinnati College of Medicine, 3333 Burnet Ave, MLC 7009, Cincinnati, OH 45229, USA. - - 2013
Necrotizing enterocolitis (NEC) is a devastating intestinal disease that afflicts 10% of extremely preterm infants. The contribution of early intestinal colonization to NEC onset is not understood, and predictive biomarkers to guide prevention are lacking. We analyzed banked stool and urine samples collected prior to disease onset from infants <29 ...
Genc Gurkan - - 2012
Objective This study was conducted to evaluate the predictive value of urinary neutrophil gelatinase-associated lipocalin (uNGAL) for acute kidney injury (AKI) among septic preterm infants.Methods Twenty-six very low-birth-weight (VLBW) babies were separated into three groups: group I, healthy preterms; group II, preterms with sepsis but without AKI; group III, preterms with sepsis ...
Tsai Yao-Te - - 2012
OBJECTIVE: To share our experience in treating a large cohort of infants with congenital vallecular cysts using endoscopic laser marsupialization. We describe the clinical characteristics of infants with pediatric vallecular cysts and compare these characteristics between infants with and without concurrent laryngomalacia and those who did or did not require ...
Ohira Toko - - 2012
Busulfan, an antineoplastic bifunctional-alkylating agent, is known to induce developmental anomalies and fetal neurotoxicity. We previously reported that busulfan induced p53-dependent neural progenitor cell apoptosis in fetal rat brain (Ohira et al., 2012). The present study was carried out to clarify the characteristics and sequence of busulfan-induced pathological changes in ...
Hammoud Majeda S - - 2012
OBJECTIVES: The prevalence and clinical significance of persistent candidemia among neonates are poorly understood. This study aimed to describe the rate and the clinical relevance of persistent candidemia over a 4-year period in Kuwait. METHODS: A retrospective chart review of infants admitted to the Neonatal Care Unit of the Maternity ...
Palojärvi Anniina - - 2012
Background:As a protective response to an inflammatory stimulus, the antigen-presenting molecules (HLA-DR) on monocytes are downregulated. If severe, the response may lead to immunodepression or immunoparalysis, associated in adults with increased morbidity and mortality. In very low birth weight (VLBW) infant, birth and intensive care present major immunologic challenges.Methods:We measured ...
Jefferies Ann L - - 2012
Objective To examine delivery indications, short-term morbidities, and use of resources for late preterm infants admitted to the neonatal intensive care unit (NICU) at a tertiary perinatal center.Study Design Data for 1137 inborn infants 340/7 to 366/7 weeks' gestational age discharged between July 2004 and December 2009 were collected from an electronic ...
Patel Shivani - - 2012
This study investigated the generalization of deferred imitation in 6-, 9-, and 12-month-old infants across auditory and visual contexts. The task involved testing for the imitation of demonstrated actions on an animal puppet 24h later. There were two independent variables defined by the background music and room of the infant's ...
Oncel Mehmet Yekta - - 2013
Treatment options for the closure of a hemodynamically significant patent ductus arteriosus (hsPDA) include medical therapy such as ibuprofen and indomethacin and surgical ligation. To evaluate the efficacy of intravenous paracetamol in preterm infants with hsPDA whose feeding was contraindicated or had feeding intolerance. Preterm infants with hsPDA were started ...
Müller Matthias J - - 2012
Abstract The selective serotonin reuptake inhibitor (SSRI) sertraline is widely used as an antidepressant agent during pregnancy and lactation because of its low placental transfer and low level of excretion into breastmilk. Symptoms such as neonatal abstinence syndrome and serotonergic overstimulation have been reported after in utero exposure to SSRIs. ...
Ilia Stavroula - - 2012
OBJECTIVES: Acute otitis media (AOM) is common in childhood, but little is known on its course very early in infancy. In this study we investigated predisposing factors, clinical characteristics, and long-term outcomes of AOM in very young infants. METHODS: One hundred sixty infants aged less than 12 months with AOM ...
Panzardi A - - 2012
Pre-weaning piglet mortality represents significant economic losses, and approximately half of this mortality occurs within the first 3 days after birth. Factors involved in postnatal mortality can also be associated with a poor growth performance until weaning. The aim of this study was to evaluate the effect of some variables ...
Leviton Alan - - 2013
We sought to disentangle the contributions of perinatal systemic inflammation and being small for gestational age (SGA) to the occurrence of low Bayley Mental Development Indices (MDIs) at the age of 2 y. We measured the concentration of 25 inflammation-related proteins in blood obtained during the first two postnatal weeks ...
Piper Hannah G - - 2012
BACKGROUND:: Infants with intestinal failure often require long-term central access for delivery of parenteral nutrition (PN). Traditionally, surgically placed, central venous catheters (CVCs) have been used. However, the complications associated with these catheters can lead to significant morbidity. Peripherally-inserted central catheters (PICCs) are potentially superior to CVCs because they tend ...
Linder Nehama - - 2012
AIM: Vancomycin is widely used to treat late-onset coagulase-negative Staphylococcus (CoNS) sepsis in very-low-birth-weight (VLBW) infants. Although vancomycin is associated with a risk of toxicity and bacterial resistance, the appropriate duration of use has not been established. This study sought to investigate the association between the duration of vancomycin therapy ...
Abdelmaaboud Mohamed - - 2012
Abstract Background: Preterm and growth-restricted babies are at high risk of milk intolerance and necrotising enterocolitis, as well as post-natal growth failure. Objective: To evaluate the effects of an "early" enteral feeding regimen, starting on day 2 after birth compared to late enteral feeding, starting on day 6 after birth ...
Nagy Andrea - - 2012
PURPOSE: The aim of the study was to compare the characteristics of ventriculosubgaleal shunts during the clinical course of posthemorrhagic and postinfectious hydrocephalus in the neonatal period. PATIENTS AND METHODS: The study comprised 102 premature babies in whom subgaleal shunt was consecutively inserted between 2006 and 2011. Seventy-two patients had ...
Zaramella Patrizia - - 2012
This case report describes a preterm newborn infant who was treated with a single dose of rasburicase for an increase in uric acid level. He died on the third day as a result of complications of hemolysis, which appeared to be precipitated by rasburicase. The patient's death was preceded by ...
Jalali Seyedeh-Zohreh - - 2012
Recent data suggest that during mechanical ventilation, lateral patient position (in which the endotracheal tube is horizontal) decreases the incidence of bacterial colonization of ventilated neonates. The objective of this study was to evaluate the influence of lateral and supine position on bacterial colonization of endotracheal tube in neonates. We ...
Horii Mariko - - 2012
A 29-year-old primigravida developed polyhydramnios at 24 weeks of gestation, requiring six serial amnioreductions. In addition, prenatal ultrasound examinations revealed a fetus with small stomach pouch, small thorax, slightly shortened limbs, and skin edema; paternal uniparental disomy 14(upd(14)pat) phenotype was suspected. At 37 weeks, the patient delivered a 2558 g female infant with ...
Park Yang Hee - - 2012
In this study, we aimed to investigate the perinatal clinical conditions of very low birth weight (VLBW) infants born to mothers with pregnancy-induced hypertension (PIH) focusing on the effects of early postnatal neutropenia. We reviewed the medical records of 191 VLBW infants who were born at Konyang University Hospital, between ...
Akcan Abdullah Barış - - 2012
Intussusception in the newborn is reported rarely, accounting for only 0.3% of all cases of intussusception (1). The ileocecal region is most commonly affected. The tetrad of clinical features includes sudden onset of abdominal colicky pain, bloody stools, a palpable abdominal mass, and vomiting. In full-term infants with neonatal intussusception, ...
Enright Brian P - - 2012
ABT-874 is an anti-IL-12/23 monoclonal antibody that binds to the p40 subunit of human IL-12 and IL-23. As part of its preclinical safety assessment, studies were conducted to assess its potential effects on pre- and postnatal development in cynomolgus monkeys. In the embryo-fetal development studies, ABT-874 was administered once weekly ...
Christensen R D - - 2012
Objective:The incidence of fetomaternal hemorrhage that is severe enough to cause neonatal anemia is not known. Owing to its relative rarity, much of the literature describing this condition is in the form of case reports and small case series. We performed a large, muiticentered, sequential, case series to determine the ...
Shoji Kensuke - - 2012
BACKGROUND:: Human parechovirus type 3 (HPeV3) infection can cause sepsis-like syndrome and meningoencephalitis in neonates and young infants. Although maculopapular rash is a reported clinical manifestation of HPeV3 infection, the frequency and detailed characteristics of rash in neonates and young infants with HPeV3 infection are unknown. METHODS:: We retrospectively reviewed ...
Molinari Claire E - - 2012
Human milk proteins provide term and preterm infants with both nutrition and protection. The objective of the present study was to examine longitudinal changes in the protein composition of term and preterm milk during the first 2 months of lactation, focusing on protein phosphorylation and glycosylation. Using gel electrophoresis, the ...
Haiden Nadja - - 2012
OBJECTIVE:To determine whether enteral application of the osmotic contrast agent Gastrografin accelerates complete meconium excretion and improves feeding tolerance in very low birth weight infants.METHODS:This study was a stratified, randomized, placebo-controlled trial in premature infants with a birth weight <1500 g and a gestational age <32 weeks who received 3 ...
Heuchan Anne Marie - - 2012
AIMS: To examine the relationship between early duct diameter and patent ductus arteriosus (PDA) symptoms. METHODS: A retrospective study of infants < 29 weeks gestation with early colour Doppler assessment of PDA diameter in whom PDA was managed conservatively, without cyclo-oxygenase inhibitor treatment. RESULTS: Gestation and birth weight, [median (range)], ...
Ochiai Shingo - - 2012
Background: A few studies have reported that the quantity of selected cytokines/chemokines in breast milk might be associated with atopic dermatitis (AD). Using the multiplex cytokine assay system, we examined cytokines/chemokines in human milk in order to identify new biomarkers related to AD. Methods: We recruited 49 infants with or ...
Alderliesten Thomas - - 2012
AIM: To compare antemortem cranial MRI with postmortem histopathological examination of the brain in full-term infants with neonatal encephalopathy following perinatal asphyxia. PATIENTS AND METHODS: In this retrospective observational cohort study, 23 infants with neonatal encephalopathy who subsequently died, were analysed. Infants underwent antemortem cranial MRI and postmortem histopathological examination ...
Ito Keiichi - - 2013
Waterston et al. have classified the risk of morbidity in infants with esophageal atresia and tracheoesophageal fistula. However, few cases of esophageal atresia with distal tracheoesophageal fistula in extremely low birth weights infants have been reported. In such infants, the selection of primary reconstruction or staged repair remains controversial. In ...
Ladhani Shamez N - - 2012
Background. Streptococcus pneumoniae is an uncommon but well-recognized cause of invasive bacterial disease in young infants. This study aimed to determine the impact of the 7-valent pneumococcal conjugate vaccine (PCV7) on invasive pneumococcal disease (IPD) in infants <90 days in England and Wales and describe their clinical characteristics following PCV7 introduction.Methods. Trends ...
Mayes Kelly - - 2012
Background: Hyperalimentation describes the increase in glucose, amino acids (AAs), and lipid intake designed to overcome postnatal growth failure in preterm infants. Preterm infants are dependent on phenylalanine metabolism to maintain tyrosine levels because of tyrosine concentration limits in parenteral nutrition (PN). We hypothesized that hyperalimentation would increase individual AA ...
Noori Shahab - - 2012
OBJECTIVE: To investigate the effect of pH on cardiac function and systemic vascular resistance (SVR) in preterm infants. STUDY DESIGN: In this prospective observational study, we evaluated hemodynamically stable, ≤30 weeks' gestation preterm infants during the first 2 postnatal weeks. Cardiac function was assessed by echocardiography at the time of ...
Lucca Juliane - - 2012
BACKGROUND: Prenatal exposure to cocaine has been associated with a wide spectrum of structural abnormalities in infant brains. The growing use of crack, a smokable and extremely addictive form of cocaine, could exacerbate the situation. OBJECTIVE: The purpose of this study was to determine the frequency, type and severity of ...
Donaldson Malcolm - - 2012
Congenital hypothyroidism, usually of the primary and permanent variety, is an eminently preventable cause of growth retardation and mental handicap whose outlook has been transformed by newborn screening, usually involving the measurement of capillary TSH. Severe primary congenital hypothyroidism, due for example to athyreosis, may result in subtle cognitive, behavioural ...
Iwata Osuke - - 2012
Background:In the rodent and human fetus, a diurnal cortisol rhythm is observed that is entrained in antiphase to the maternal rhythm. However, after birth, the adrenal circadian rhythm becomes unsynchronized with the clock time, and an adult-type, 24-h rhythm is observed only after a few months. Little is known about ...
Ray Kristin N - - 2012
OBJECTIVES:To examine hospitalizations and length of stay (LOS) for infants aged <1 year in rural and urban counties, hypothesizing that infants living in rural counties experience significantly different hospital use compared with urban infants.METHODS:Birth certificates for infants born in California hospitals between 1993 and 2005 and surviving to discharge were ...
Rath Mirjam E A - - 2012
BACKGROUND: Neonates with Rhesus c (Rh c) hemolytic disease of the fetus and newborn (HDFN) are often managed in the same way as neonates with Rhesus D (Rh D) HDFN, although evidence to support this policy is limited. The objective of this study was to evaluate neonatal outcome in severe Rh c HDFN ...
Marshall Guillermo - - 2012
To develop a prediction model for hospital length of stay (LOS) in very low birth weight (VLBW) infants and to compare this outcome among 20 centers within a neonatal network. Data from 7,599 infants with birth weights of 500-1,500 g born between the years 2001-2008 were prospectively collected. The Cox ...
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