Search Results
Results 251 - 300 of 1824
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van der Burg Jelske W - - 2013
The offspring of obese women are at increased risk for systemic inflammation. Blood concentrations of inflammatory proteins in preterm newborns of obese women have not been reported. To compare blood concentrations in the highest quartile for gestational age of inflammatory proteins and day of blood specimen collection on two days ...
Suganuma Hiroki - - 2013
In premature infants, many factors influence the function of renal tubules, such as asphyxia, respiratory disorders, use of high-concentration oxygen, hypotension, and drug administration. When tubular ischemia and oxidative stress develop due to renal microcirculatory pathology, urinary L-type fatty acid-binding protein levels (L-FABP) increase. We measured urinary L-FABP levels over ...
Sampson Mario R - - 2013
Acyclovir is used to treat herpes infections in preterm and term infants; however, the influence of maturation on drug disposition and dosing requirements is poorly characterized in this population. We administered intravenous acyclovir to preterm and term infants <31 days postnatal age and collected plasma samples. We performed a population ...
Wagner Erin A - - 2013
OBJECTIVE:We characterized breastfeeding concerns from open-text maternal responses and determined their association with stopping breastfeeding by 60 days (stopping breastfeeding) and feeding any formula between 30 and 60 days (formula use).METHODS:We assessed breastfeeding support, intentions, and concerns in 532 expectant primiparas and conducted follow-up interviews at 0, 3, 7, 14, ...
Ge Wen J - - 2013
OBJECTIVE:To develop and validate a statistical prediction model spanning the severity range of neonatal outcomes in infants born at ≤30 weeks' gestation.METHODS:A national cohort of infants, born at 23 to 30 weeks' gestation and admitted to level III NICUs in Canada in 2010-2011, was identified from the Canadian Neonatal Network ...
Atsumi Naotaka - - 2013
This report describes a 2-month-old male infant with a double aortic arch (DAA) complicated by aortoesophageal fistula (AEF) and aortotracheal fistula (ATF). He was intubated with an endotracheal tube at birth because of neonatal asphyxia. A nasogastric tube was also placed for gastric decompression and milk feeding. On the 74th ...
Khositseth Anant - - 2013
Background: Perfusion index (PI) could reflect peripheral flow. Preterm infants with hemodynamically significant patent ductus arteriosus (hsPDA) will have left-to-right shunt across PDA causing less blood flow to the lower legs. Objective: To evaluate pre- and postductal PI differences (ΔPI) in hsPDA. Methods: Preterm infants with gestational age <34 weeks ...
Yang Wen-Chieh - - 2013
Severe dehydration is generally believed to be a cause of significant hyperbilirubinemia in newborn babies. This study aimed to analyze the weight loss of healthy term newborn infants at 24, 48 and 72 hours after birth to predict significant hyperbilirubinemia at 72 hours. From January 2007 to December 2008, we ...
Kuzniewicz Michael W - - 2013
The increased vulnerability of late preterm infants is no longer a novel concept in neonatology, with many studies documenting excess morbidity and mortality in these infants during the birth hospitalization. Because outcomes related to gestational age constitute a continuum, it is important to analyze data from the gestational age groups ...
Garcia Guerra Gonzalo - - 2013
To determine whether sedation/analgesia drugs used before, during, and after infant cardiac surgery are associated with neurocognitive and functional outcomes. Some animal models suggest neurotoxic effects of anesthetic drugs on the developing brain; however, potential human effects are unknown. Whether these results can be extrapolated to humans is unknown. Prospective ...
Thakkar Sagar K - - 2013
A recent report suggested that human milk (HM) composition not only changes with lactation stages but also vary according to gender of the offspring. In spite of available literature, the dynamic changes of HM composition still remain to be completely explored and characterized. Progress in analytical technologies together with quantitative ...
Graves Barbara W - - 2013
The transition from intrauterine to extrauterine life is a complex adaptation. Although, in a sense, the entire time in utero is in preparation for this transition, there are many specific anatomic and physiologic changes that take place in the weeks and days leading up to labor that facilitate a healthy ...
Sullivan Elizabeth A - - 2013
There is a need to have uniformed reporting of perinatal mortality for births following assisted reproductive technology (ART) treatment to enable international comparison and benchmarking of ART practice. The Australian and New Zealand Assisted Reproduction Database was used in this study. Births of >= 20 weeks gestation and/or >= 400 ...
Lam Hugh Simon - - 2013
Early detection and treatment of infected preterm infants could decrease morbidity and mortality. Neutrophil CD64 has been shown to be an excellent early diagnostic biomarker of late-onset sepsis (LOS) and necrotizing enterocolitis (NEC). We aimed to study whether using CD64 as a daily surveillance biomarker could predict LOS/NEC before clinical ...
Neary Elaine - - 2013
Background: Few published data exist to guide interpretation of coagulation times in extremely premature infants. Objective: To determine coagulation reference ranges on day 1 of life in extremely premature infants. Methods: A retrospective review of day 1 coagulation tests was performed in 144 infants <27 weeks' gestation between 2004 and ...
Harder Björn C - - 2013
To report on the therapeutic effect of intravitreal low-dose bevacizumab for treatment for retinopathy of prematurity (ROP). The single-centre retrospective, non-comparative case series study included all infants who consecutively underwent intravitreal injection of 0.375 mg bevacizumab (0.03 ml) under light sedation in topical anaesthesia as therapy of ROP in zone I or ...
Mohamed Sarar - - 2013
Tyrosinemia type 1 (TT1) is an autosomal recessive disorder caused by deficiency of the enzyme fumarylacetoacetate hydrolase (FAH). TT1 usually presents in infancy with features suggestive of liver disease or with sepsis-like symptoms. We report two Saudi siblings with TT1. Case 1 was a male infant who presented at 2 ...
Ando Hitoshi - - 2013
Zonisamide, an antiepileptic drug, is excreted into breast milk, but information regarding the safety of breast-feeding while using this drug is limited. We present the cases of two nursing mothers, taking 300 and 100 mg/day zonisamide. At 5 days after delivery, the milk concentrations and relative infant doses of the drug ...
Sommers Ross - - 2013
Background:This study tested if measures of central nervous system (CNS) immaturity reflected by amplitude integrated EEG (aEEG) and associated clinical morbidities are determinants of length of hospitalization among late preterm infants born at 34 weeks.Methods:This was a prospective cohort study of infants with a gestational age of 34(0) to 34(6) ...
Gahalaut Pratik - - 2013
Vitamin K deficiency bleeding (VKDB) disorder is an uncommon entity, which occurs due to inadequate activity of vitamin K-dependant coagulation factors. An 8-months-old exclusively breast-fed male infant presented with multiple, purpuric and nodular non-collapsible swellings on trunk of 4 days duration. Investigations revealed raised activated partial thromboplastin time and prothrombintime. ...
Puttgen Katherine B - - 2013
We sought to determine the effect of propranolol on cardiovascular and blood glucose parameters in infants with symptomatic infantile hemangiomas who were hospitalized for initiation of treatment, and to analyze adverse effects of propranolol throughout the course of inpatient and outpatient treatment. A retrospective cohort analysis was performed on 50 ...
Zagólski Olaf - - 2013
The study sought to evaluate the influence of gastroesophageal reflux disease (GERD) and allergy on subacute rhinitis in infants. Mothers of 74 infants with subacute rhinitis completed the Infant Gastroesophageal Reflux Questionnaire Revised. Participants with GERD were randomized to undergo one of the following regimens for 10 days: use of ...
Ombeva Om - - 2013
The World Health Organization (WHO) reports estimate that 85% of newborn deaths are due to infections, prematurity and fetal distress. These conditions are risk factors for upper GI bleeding (UGIB) in sick neonates. UGIB is associated with poor neonatal outcomes such as prolonged hospitalisation and poor weight gain. The magnitude ...
Baqui Abdullah H AH Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA. - - 2013
Because access to care is limited in settings with high mortality, exclusive reliance on the current recommendation of 7-10 days of parenteral antibiotic treatment is a barrier to provision of adequate treatment of newborn infections. We are conducting a trial to determine if simplified antibiotic regimens with fewer injections are ...
Zaidi Anita K M AK Department of Paediatrics and Child Health, Aga Khan University, Karachi, - - 2013
Infection in young infants is a major cause of morbidity and mortality in low-middle income countries, with high neonatal mortality rates. Timely case management is lifesaving, but the current standard of hospitalization for parenteral antibiotic therapy is not always feasible. Alternative, simpler antibiotic regimens that could be used in outpatient ...
- - 2013
The World Health Organization recommends hospitalization and injectable antibiotic treatment for young infants (0-59 days old), who present with signs of possible serious bacterial infection. Fast breathing alone is not associated with a high mortality risk for young infants and has been treated with oral antibiotics in some settings. This ...
Moore Tiffany A TA College of Nursing, University of Nebraska Medical Center, Omaha, NE 68198-5330, - - 2013
Feeding intolerance (FI) in preterm infants is common but the etiology remains unclear. This study examined FI as a stress-related disease involving brain-gut interactions and tested the model of allostatic load and complications of prematurity. Specific aims were to describe demographic/medical variables and biomarker levels at each time and over ...
Bruno Christie J - - 2013
Few data regarding causes and outcomes of haemorrhagic stroke (HS) in term neonates are available. We characterised risk factors, mechanism and short-term outcomes in term and late preterm neonates with acute HS. Prospective cohort. Single-centre tertiary care stroke registry. Term and late preterm neonates (≥34 weeks gestation), born 2004-2010, with ...
Brownfoot Fiona C - - 2013
Despite the widespread use of antenatal corticosteroids to prevent respiratory distress syndrome in preterm infants, there is currently no consensus as to the type of corticosteroid to use; nor the dose, frequency, timing of use or the route of administration. To assess the effects of different corticosteroid regimens for women ...
da Silva Simone Aparecida Basso - - 2013
Abstract Aims: Compare the need for neonatal resuscitation procedures between newborn infants with and without meningomyelocele (MMC). Results: This retrospective case-control study included 94 neonates with MMC, defined as open spinal dysraphism with exposure of nervous tissue, and 94 controls without malformations, paired with MMC infants by gender, mode of ...
Reeves Travis D - - 2013
To determine the dimensions of the nasal cavity in infants with congenital pyriform aperture stenosis (CPAS). The nasal cavities of seven children with CPAS were identified and were compared to the nasal cavities of 13 neonates (<30 days old) who had received CT scans for other indications. The width of ...
Raets Marlou M A - - 2013
Purpose:To report the incidence of cerebral sinovenous thrombosis (CSVT) in a prospective cohort of preterm infants with a gestational age of less than 29 weeks.Materials and Methods:The local medical ethics review board approved this study, and written parental consent was obtained. Preterm infants with a gestational age of less than ...
Kempley Stephen - - 2013
To describe feeding and gastrointestinal outcomes in growth-restricted infants <29 weeks' gestation and to determine the rate of feed advancement which they tolerate. Analysis of prospectively collected data from a randomised feeding trial, the Abnormal Doppler Enteral Prescription Trial (ADEPT). 54 neonatal units in the UK and Ireland. 404 preterm, ...
Papoff P - - 2013
The objective was to review and compare outcomes after tongue-lip adhesion (TLA) and mandibular distraction osteogenesis (MDO) in infants with severe breathing difficulties related to Pierre Robin sequence (PRS). A single-centre retrospective (2002-2012) study was carried out; 18 infants with severe breathing difficulties related to PRS resistant to conservative treatment, ...
Hirfanoglu Ibrahim M - - 2013
Gamma-glutamyltransferase (GGT) is commonly measured in newborn infants as a sensitive liver function test, however reference ranges mostly based on early studies including relatively small number of patients. The aim of this study was to emphasise recently changed GGT values due to changed newborns profile admitted to neonatal intensive care ...
Giusti Delphine - - 2013
Measles is a highly contagious viral infection causing congenital infections with a risk of neurological complications in the newborn. Two cases of measles, which occurred in pregnant women within 14 days before the delivery, are described. Mother-to-child transmission of the virus was documented in the newborns either by RT-PCR in ...
Collins C L - - 2013
The objectives of this study were (1) to devise a nasal trauma score for preterm infants receiving non-invasive respiratory support, (2) to compare the incidence of nasal trauma in preterm infants <32 weeks gestation randomised to either nasal continuous positive airway pressure (NCPAP) or heated humidified high-Flow nasal cannulae (HHHFNC), in ...
Loui Andrea - - 2013
Abstract Aim: To assess the impact of a high enteral protein nutrition strategy in human milk-fed very low birth weight (VLBW) infants (<1500 g) on growth during the first 5 weeks of life. Design: Weight, length and head circumference of VLBW infants were recorded after introduction of a high protein ...
Surran B - - 2013
Objective:To compare the efficacy of clonidine versus phenobarbital in reducing morphine sulfate treatment days for neonatal abstinence syndrome (NAS).Study Design:Prospective, non-blinded, block randomized trial at a single level III NICU (Neonatal Intensive Care Unit). Eligible infants were treated with a combination of medications as per protocol. Primary outcome was treatment ...
Moenkemeyer Florian - - 2013
To investigate the relationship between early right ventricular function measured by tissue Doppler imaging and early outcome measures in newborn infants with congenital diaphragmatic hernia. Retrospective cohort study. Surgical neonatal ICU within a regional pediatric center. Twenty newborn infants with congenital diaphragmatic hernia. None. Analysis of serial echocardiograms in a ...
Hirata Katsuya - - 2013
Objective The aim of this article is to evaluate the accuracy, precision, and safety of transcutaneous carbon dioxide tension (TcPCO2) monitoring at different electrode temperatures in preterm infants in the early postnatal period.Study Design A total of 26 neonates with a median birth weight of 974 g (432-1,694 g) and ...
Oh Jung Wha - - 2013
A 2-day-old male infant was referred to hospital because he was continually moaning. Massive pneumoperitoneum was observed on plain radiographs on the day of admission. This case is unique in that the massive pneumoperitoneum with meconium-stained peritoneal fluid was not associated with any evidence of bowel perforation seen on laparotomy.
Watanabe Toshihiko - - 2013
Milk curd syndrome was first reported in the 1960s, but was gradually forgotten because of its low incidence thereafter. This condition in pre-term infants has been reported over the last decade and has again attracted neonatologists' attention. The present report describes a pre-term infant with milk curd syndrome. Abdominal distension ...
van den Berg Jolice P - - 2013
Infections are common in preterm infants and cause differences in cytokine levels. Aim of this study was to measure cytokine levels in preterm infants during the first year of life and to determine the effect of feeding a specific non-digestible carbohydrate mixture (scGOS/lcFOS/pAOS). Furthermore, other perinatal factors in relation to ...
Frenette Priscilla - - 2013
Objectives: To compare risks of infection and prematurity-related outcomes according to latency periods among women with preterm prelabour rupture of membranes (PPROM). Methods: Women with PPROM occurring between 24+0 and 36+6 weeks of gestation were identified from a provincial population-based perinatal database in Nova Scotia. The primary outcomes included composite ...
Zhang Linjie - - 2013
Airway oedema and mucus plugging are the predominant pathological features in infants with acute viral bronchiolitis. Nebulised hypertonic saline solution may reduce these pathological changes and decrease airway obstruction. To assess the effects of nebulised hypertonic (≥ 3%) saline solution in infants with acute viral bronchiolitis. We searched CENTRAL 2013, ...
Anderson Margot M Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao - - 2014
As data about the causes of neonatal sepsis in low-income countries are inadequate, we reviewed the etiology and antibiotic susceptibilities of bacteremia in young infants in Laos. As Staphylococcus aureus is the leading cause of bacteremia in Lao infants, we also examined risk factors for this infection, in particular the ...
Tsai Ming-Horng - - 2013
Late-onset sepsis (LOS) is a common complication in the neonatal intensive care unit (NICU). We aimed to describe the epidemiology, clinical characteristics, and risk factors for adverse outcome in neonates with LOS. We conducted a cohort study of all neonates with LOS at the NICU of a Tertiary Taiwan Medical ...
Saadah Loai M - - 2013
To identify subgroups of premature infants who may benefit from palivizumab prophylaxis during nosocomial outbreaks of respiratory syncytial virus (RSV) infection. Retrospective analysis using an artificial intelligence model. Level IIIB, 35-bed, neonatal intensive care unit (NICU) at a tertiary care hospital in the United Arab Emirates. One hundred seventy six ...
Sellmer Anna - - 2013
To assess the association between a patent ductus arteriosus (PDA) on day 3 of life and severe morbidity and mortality. Cohort study. Neonatal Intensive Care Unit, Aarhus University Hospital, Denmark. All neonates with a gestational age less than 32 weeks admitted from 2010 to 2012. All neonates (n=183) were routinely ...
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