Search Results
Results 201 - 250 of 1842
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Kantake Masato M Perinatal Medical Center, Juntendo University Urayasu Hospital, Urayasu, Chiba, - - 2014
To examine the environmental effects on cytosine methylation of preterm infant's DNA, because early life experiences are considered to influence the physiological and mental health of an individual through epigenetic modification of DNA. A prospective cohort study, comparison of epigenetic differences in the glucocorticoid receptor (GR) gene between healthy term ...
Dyson Rebecca M RM Mothers and Babies Research Centre, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia; Discipline of Paediatrics and Child Health, School of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia; Illawarra Health and Medical Research Institute and Graduate School of Medicine, University of Wollongong, Wollongong, NSW, - - 2014
Excessive vasodilatation during the perinatal period is associated with cardiorespiratory instability in preterm neonates. Little evidence of the mechanisms controlling microvascular tone during circulatory transition exists. We hypothesised that hydrogen sulphide (H2S), an important regulator of microvascular reactivity and central cardiac function in adults and animal models, may contribute to ...
Mourani Peter M PM Pediatric Heart Lung Center, University of Colorado School of Medicine/Children's Hospital Colorado, Aurora, CO. Electronic address: - - 2013
To determine the incidence and risk factors for readmission to the intensive care unit (ICU) among preterm infants who required mechanical ventilation at birth. We studied preterm newborns (birth weight 500-1250 g) who required mechanical ventilation at birth and were enrolled in a multicenter trial of inhaled nitric oxide therapy. ...
Fleddermann Manja M Dr. von Hauner Children's Hospital, University of Munich Medical Centre, Munich, - - 2013
Protein source, macronutrient composition and content of long chain-polyunsaturated fatty acids (LC-PUFA) of infant formulae may influence infant growth. We aimed to assess the effect of a modified infant formula on growth. In a randomized, double-blind trial, 213 healthy term infants consumed isoenergetic study formulae (intervention formula - IF, control ...
Swann Olivia O aUniversity of Malawi College of Medicine, Blantyre, Malawi bCentre for Immunity, Infection and Evolution, Edinburgh, UK cMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi dUniversity of Liverpool, Liverpool, UK eTownsville Hospital, Douglas, Queensland, Australia fUniversity of Edinburgh, Edinburgh, UK gLiverpool School of Tropical Medicine, Liverpool, - - 2013
Neonatal meningitis is an important cause of morbidity in sub-Saharan Africa and requires urgent empiric treatment with parenteral administered antibiotics. Here we describe the etiology, antimicrobial susceptibility and suitability of the World Health Organization (WHO) first-line recommended antibiotics (penicillin and gentamicin) for bacterial meningitis in young infants in Malawi. We ...
Slusher Tina M - - 2013
Severe neonatal jaundice and its progression to kernicterus is a leading cause of death and disability among newborns in poorly-resourced countries, particularly in sub-Saharan Africa. The standard treatment for jaundice using conventional phototherapy (CPT) with electric artificial blue light sources is often hampered by the lack of (functional) CPT devices ...
Quach Caroline C Division of Infection Control, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, - - 2014
Background. Despite implementation of recommended best practices, our central line-associated bloodstream infection (CLABSI) rates remained high. Our objective was to describe the impact of chlorhexidine gluconate (CHG) bathing on CLABSI rates in neonates. Methods. Infants with a central venous catheter (CVC) admitted to the neonatal intensive care unit from April 2009 to ...
Vesoulis Zachary A ZA Department of Pediatrics, Washington University School of Medicine, St. Louis, - - 2013
Background:Previous studies of very preterm (VPT) infants have shown a wide range of seizure prevalence and association with intraventricular hemorrhage (IVH), white matter injury (WMI) and death. However, the impact of seizures on neurodevelopment is not well known. We hypothesized that seizures in the first three days after VPT birth ...
Helfer Sven S Department of Pediatric Cardiology, Charité University Medical Center, Berlin, - - 2013
Preterm infants may have cardiac stress related to patent ductus arteriosus (PDA) or bronchopulmonary dysplasia (BPD). In this study, we examined the development of cardiac function in preterm infants by measuring tissue Doppler-derived peak systolic strain (PSS) and strain rate (PSSR) in the first 28 days of life. Peak systolic strain ...
van Sorge Arlette J AJ Department of Ophthalmology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: - - 2013
To study the incidence and risk factors for retinopathy of prematurity (ROP) in the Netherlands. Prospective, approximating population-based study that included infants with gestational age (GA) <32 weeks and/or birth weight (BW) <1500 g born in 2009. Pediatricians and ophthalmologists of all hospitals involved in care for premature infants reported ...
Schmiedchen Bettina B Department of Physiology and Pathophysiology, University of Potsdam, Nuthetal, - - 2013
Background: The relative dose response (RDR) test, which quantifies the increase in serum retinol after vitamin A administration, is a qualitative measure of liver vitamin A stores. Particularly in preterm infants, the feasibility of the RDR test involving blood is critically dependent on small sample volumes. Objectives: This study aimed ...
Vergales Brooke D BD Division of Neonatology, Department of Pediatrics, University of Virginia, Charlottesville, - - 2013
Objective Asphyxia can lead to autonomic nervous system dysfunction, including depressed heart rate variability (HRV). We tested the hypothesis that low HRV is associated with adverse short-term outcomes of abnormalities on electroencephalogram (EEG) and brain magnetic resonance imaging (MRI) and death in neonates with hypoxic ischemic encephalopathy (HIE). Study Design Neonates undergoing ...
Adam Ryan J RJ 1 Department of Internal - - 2013
Air trapping and airflow obstruction are being increasingly identified in infants with cystic fibrosis. These findings are commonly attributed to airway infection, inflammation, and mucus buildup. To learn if air trapping and airflow obstruction are present before the onset of airway infection and inflammation in cystic fibrosis. On the day ...
Kasapkara Ciğdem Seher CS Pediatric Metabolic Unit - - 2013
Abstract Neonatal-onset propionic acidemia (PA), the most common form, is characterized by poor feeding, vomiting, and somnolence in the first days of life in a previously healthy infant, followed by lethargy, seizures, and can progress to coma if not identified and treated appropriately. It is frequently accompanied by metabolic acidosis ...
Vatlach Scarlet S Department of Neonatology, University Children's Hospital, Tuebingen, - - 2013
Background: Given the lack of a licensed product (LP), extemporaneous caffeine citrate (ECC) has been used by many hospital pharmacies. Objectives: Since July 2011, an LP has been available in Germany. We prospectively compared the safety profile of ECC and LP in preterm infants with apnea of prematurity. Methods: Between ...
Hakan Nilay - - 2013
We aimed to determine reference values of perfusion index (PI) in healthy newborns during the early neonatal period. Preductal (right hand) and postductal (foot) PI values were assessed during the first 5 days of life by using a new generation pulse oximetry. A total of 241 newborn infants (196 [81.3 %] term ...
Nakamura Toshihiko T Department of Pediatrics, National Organization Hospital, Nishi-Saitama Chuo National Hospital, Tokorozawa, - - 2013
Reported herein is the first case of a remarkably delayed occurrence of normal surfactant composition in an extremely preterm infant who required a total of 15 doses of artificial pulmonary surfactant (Surfacten®). A male infant, born at 26 weeks gestation, developed respiratory distress at birth. Chest radiography was consistent with ...
Bly Eleanor E University of Washington Family Medicine Residency, Seattle, WA, - - 2013
It's unclear what age is best to start vitamin D supplementation because no comparison studies exist. That said, breastfed infants who take vitamin D beginning at 3 to 5 days of life don't develop rickets. Starting infants on vitamin D supplementation at one to 36 months of age reduces the ...
Mitt P P Department of Infection Control, Tartu University Hospital, Tartu, Estonia. Electronic address: - - 2013
Few studies provide rates of nosocomial bloodstream infections (BSIs) in mixed neonatal and paediatric intensive care units (PICUs). To determine the rate, pathogens and outcome of BSIs in an Estonian PICU. Data were collected prospectively from 1st January 2004 to 31st December 2008 in the PICU of Tartu University Hospital. ...
Hegar Badriul B Department of Child Health, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, - - 2013
Regurgitation is known to peak at the age of 3-4 months, with a sharp decrease around the age of 6 months. Little is known about the natural evolution of infants who still regurgitate after the age of 6 months. Hundred thirty-one infants older than 6 months regurgitating more than once ...
Oberhelman Sara S SS Department of Family Medicine, Mayo Clinic, Rochester, MN. Electronic address: - - 2013
To determine whether a single monthly supplement is as effective as a daily maternal supplement in increasing breast milk vitamin D to achieve vitamin D sufficiency in their infants. Forty mothers with exclusively breast-fed infants were randomized to receive oral cholecalciferol (vitamin D3) 5000 IU/d for 28 days or 150,000 ...
Inoue Ayumi A Drug Safety Research Laboratories, Shin Nippon Biomedical Laboratories (SNBL), Ltd, Kagoshima, Japan; Division of Biomodeling, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, - - 2013
Thiamazole, an anti-hyperthyroidism agent, was administered orally to pregnant cynomolgus monkeys at doses of 2.0 and 3.5 mg/kg per day from GD 120 to GD 150 to investigate effects on behavioral development of their infants. Swelling of the throat region due to enlargement of the thyroid glands was observed at birth ...
Simao Razao R Department of Public Health of Cabinda, - - 2013
To critically discuss, describe and analyze the data on infant mortality provided by public health services of Cabinda, Angola. The deaths of children aged less than one year old in 2007 and 2008 were analyzed in the Cabinda province. Provincial hospital records and those of the WHO office were used ...
Simic Klaric Andrea - - 2013
Aim. The objective of this study is to compare head circumferences (HCs) measured on the day of delivery and on the third day after delivery. Method. A total of 499 children born in the maternity department were recruited for the study. HC was measured in centimeters immediately after birth and ...
Schulkind Lisa L Trinity College, Department of Economics, 300 Summit Street, Hartford 06106, - - 2013
Scheduling births for non-medical reasons has become an increasingly common practice in the United States and around the world. We exploit a natural experiment created by child tax benefits, which rewards births that occur just before the new year, to better understand the full costs of elective c-sections and inductions. ...
Ishida Yasushi - - 2013
To evaluate the birth and discharge dates of neonates and analyze their distribution over days of the week and the old lunar calendar. A retrospective cohort on the neonates discharged in the years 1990, 2000, 2005, and 2010 was conducted in a general hospital in Tokyo, Japan. Data are represented ...
Olhager Elisabeth - - 2013
Dopamine is used as an inotropic medication in preterm infants. The preterm human blood brain barrier (BBB) is permeable to intravascular dopamine and the impact of exogenous dopamine on the preterm brain remains unknown. The preterm lamb model may be suitable for studying the cerebral impact of dopamine therapy if ...
Peng Wansheng - - 2013
To assess the effect of volume-targeted ventilation (VTV) compared with pressure-limited ventilation (PLV) in preterm infants. We searched the Cochrane Library (Issue 3, 2013), PubMed (1966 to 5 March 2013), China National Knowledge Infrastructure (CNKI) and periodical databases (1979 to 5 March 2013). We selected randomised controlled trials (RCTs) and ...
Feder Henry M HM Jr Department of Pediatrics, Connecticut Children's Medical Center, Hartford, CT, USA; Department of Family Medicine, Connecticut Children's Medical Center, Hartford, CT, USA; University of Connecticut Health Center, Farmington, CT, USA. Electronic address: - - 2014
A previously well infant aged 9 months presented with an acute, self-limiting illness characterised by high fever and a papular eruption that started on the face. Although fever subsided within 3 days, the rash worsened and extended over the whole body, with some papules evolving into vesiculobullous lesions. The infant ...
Muñoz K - - 2013
The nephrotoxic and carcinogenic mycotoxin ochratoxin A (OTA) is a worldwide contaminant in food commodities and also found frequently in human biological fluids. Dietary contaminants ingested by nursing mothers can appear in breast milk. But the rate of lactational transfer of OTA has not been investigated so far at various ...
Liu Ping - - 2013
Chlorpyrifos (CPF) is one of the most widely used organophosphorous pesticides in China. However, few reports on CPF pesticide exposure and body burden of infants at 2 years of age in China are available. The aim of this study was to assess the exposure level and the absorbed daily dose (ADD) ...
Behme Renee M - - 2013
Abstract The relationship between thyroid function, mode of delivery, and illness in infants 34-36 weeks' gestation has not been well studied. We hypothesized that infants born by cesarean delivery and those with increased illness would have a reduction in thyroxine (T4) following birth. Total T4 and thyroid-stimulating hormone were obtained ...
Guo Ying - - 2013
Despite the widespread usage of phthalates and parabens in personal care products (PCPs), little is known about concentrations and profiles as well as human exposure to these compounds through the use of PCPs. In this study, nine phthalates and four parabens were determined in 170 PCPs (41 rinse-off and 109 ...
Takahashi Kazumasa - - 2013
Background: Tau protein is a microtubule-associated protein that is present in axons. Elevated tau protein levels in cerebrospinal fluid or serum are associated with several central nervous system diseases and can indicate neuronal injury. Objective: In the present study, we measured and then compared serum tau protein levels between infants ...
Prodhan Parthak - - 2013
The objective of this study was to identify types of neonatal diseases associated with prolonged (≥21 days) extracorporeal membrane oxygenation (ECMO), characteristics of survivors and nonsurvivors among those requiring prolonged ECMO, and factors associated with mortality. Data were obtained from the Extracorporeal Life Support Organization registry over the period from ...
Christmann Viola - - 2013
Bone mineralisation in preterm infants is related to supply of calcium and phosphorus. We increased the amount of minerals in parenteral nutrition for preterm infants and evaluated postnatal calcium and phosphorus metabolism in relation to mineral and vitamin D intake. Preterm infants, included on their first day of life, received ...
Rosenfeld Keidar H - - 2013
Objective:To study whether Johan Sebastian Bach music has a lowering effect on resting energy expenditure (REE) similar to that of Wolfgang Amadeus Mozart music.Study Design:Prospective, randomized clinical trial with cross-over in 12 healthy, appropriate weights for gestational age (GA), gavage fed, metabolically stable, preterm infants. Infants were randomized to a ...
Olsen Irene E - - 2013
To evaluate the relationship between nutritional intake (kcalories, protein) and weight and length growth in preterm infants, and describe their metabolic tolerance with a focus on those with high protein intake (≥4.6 g/kg/day). Secondary analysis of data from appropriate-for-gestational age preterm infants in 28 day randomized clinical trial that evaluated growth, ...
Ploegstra Wieteke M - - 2013
The quality of general movements (GMs) is a widely used criterion to assess neurological dysfunction in young infants. It is unknown, however, whether the birth process influences the motor repertoire of healthy full term infants during the first week after birth. To assess the quality of GMs and to determine ...
Can Emrah - - 2013
Abstract Objective: To describe the complication profiles of central and non-central 1 Fr PICCs in neonates. Methods: A total of 123 neonates (73 males and 50 females) were included in this study. PICCs with distal tips in the superior or inferior vena cava were defined as central, and those with ...
Kaushal S S Division of Cardiac Surgery, University of Maryland Medical Center, Chicago, IL, - - 2014
Primary graft failure is the major cause of mortality in infant HTx. The aim of this study was to characterize the indication and outcomes of infants requiring ECMO support due to primary graft failure after HTx. We performed a retrospective review of all infants (<1 yr) who underwent Htx from three ...
Nenna Raffaella R Department of Paediatrics, "Sapienza" University of Rome, Rome, - - 2013
Our study was aimed to evaluate the efficacy of 7% hypertonic saline and 0.1% hyaluronic acid (7% HS-HA) given by inhalation, in infants hospitalized for mild-to-moderate bronchiolitis. In a double-blind controlled study, 39 infants (23 boys) <7 months of age (median age 2 months) were enrolled and randomly assigned to ...
Hartley Caroline - - 2013
Infants within neonatal intensive care units can receive multiple medically essential painful procedures a day. How they respond to these stimuli, how best to alleviate the negative effects, and the long-term consequences for the infant are all significant questions that have yet to be fully answered. In recent years several ...
Gutiérrez-Castrellón Pedro P Hospital General Dr. Manuel Gea - - 2013
Infant formulae are being supplemented with probiotics, prebiotics, or symbiotic despite uncertainties regarding their efficacy. Mexican agave is an interesting source of fructans with particular features and with potential prebiotic effects. RCT in 600 healthy term babies (20 ± 7 days), allocated to receive standard infant formula (control) or infant ...
Gemiyo Deribe - - 2013
Stagnant early growth and mortality are the major impediments for sheep production in southern Ethiopia. We evaluated the effects of non-genetic factors on early growth performance of lambs in Halaba district with 467 lambs owned by 60 households. Body weights (kilograms) of lambs at birth, 30, 60, 90, 120, and ...
Freyne B - - 2013
Biologic plausibility of risk factors is required to strengthen risk reduction strategies. The "triple risk model" for SIDS describes the interplay of a vulnerable infant, during a critical developmental period, interacting with external stressors (2). Identified external stressors are the supine sleep position and smoke exposure (3). Airway occlusion has ...
Bartholomew Julie - - 2013
Objectives: To identify maternal and infant characteristics associated with reduced growth velocity (GV) in extremely premature newborns. Methods: We evaluated 1,187 infants born between 23 and 27 weeks' gestation at 14 institutions between 2002 and 2004 who survived until day 28 to identify the maternal and infant characteristics associated with ...
Becquet Odile - - 2013
The benefit to risk ratio of the treatment with erythropoietin (EPO) as a means of limiting the number of transfusions in very preterm infants during hospitalization, seems to be modest since the adoption of restrictive transfusion criteria and of policy limiting phlebotomy losses. We therefore aim to evaluate the factors ...
Tully Kristin P - - 2013
breast-feeding outcomes are often worse after caesarean section compared to vaginal childbirth. this study characterises mothers' breast-feeding intentions and their infant feeding experiences after caesarean childbirth. data are from 115 mothers on a postnatal unit in Northeast England during February 2006-March 2009. Interviews were conducted an average of 1.5 days ...
Charlesworth Paul - - 2013
Introduction The surgical management of gastroschisis (GS) is controversial. The most commonly used strategy for abdominal wall closure is surgery on day 1 of life with the aim of primary closure (PC) or construction of a surgical silo (SS) and secondary closure thereafter. The other widely used technique is application ...
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