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Meyer Sascha S Neonatal Intensive Care Unit, Department of Pediatrics and Neonatology, University Children's Hospital of Saarland, Homburg, - - 2014
Background: Prematurity and the associated risk for bronchopulmonary dysplasia (BPD) remain a significant threat to extremely low birth weight (ELBW) infants. Vitamin A has been considered a therapeutic alternative in reducing the rate of BPD and mortality. Objectives: To investigate whether early postnatal, additional high-dose oral vitamin A supplementation for ...
Griesmaier Elke E Department of Pediatrics II, Innsbruck Medical University, Innsbruck, - - 2014
Background: The amplitude-integrated electroencephalogram (aEEG) is a valuable tool for monitoring brain function in preterm infants. Several studies have discussed sex-related differences regarding neonatal morbidity and mortality. To date, no study has been published specifically evaluating potential sex-related differences in aEEG parameters. Objective: The aim of this study was to ...
Khuzakhmetova Venera V Kazan Institute of Biochemistry and Biophysics Kazan Scientific Center of the Russian Academy of Sciences, 420111, PostBox 30, Kazan, - - 2014
The kinetics of the phasic synchronous and delayed asynchronous release of acetylcholine quanta was studied at the neuromuscular junctions of aging rats from infant to mature animals at various frequencies of rhythmic stimulation of the motor nerve. We found that in infants 6 (P6) and 10 (P10) days after birth ...
Hoffend Charlotte C Department of Legal Medicine, University Medical Center Hamburg-Eppendorf, Butenfeld 34, 22529, Hamburg, - - 2014
The incidence of sudden infant death syndrome (SIDS) has declined substantially, but the proportion of sudden unexpected death in infancy (SUDI) in neonates, <7 days old, has increased among all SUDI cases in the first year of life. The aim of this study was to analyze circumstances and common features of ...
Yakut Ibrahim I Department of Pediatrics, Ankara Pediatric & Pediatric Hematology, Oncology Training and Research Hospital, Ankara, - - 2014
We investigate the efficacy of serial ischemia-modified albumin (IMA) measurements in diagnosis and follow-up of necrotizing enterocolitis (NEC), and compare its effectiveness with C-reactive protein (CRP), interleukin-6 (IL-6), in NEC. Preterm infants, whose gestational age and weight matched each other, were grouped as control (n = 36) and NEC (n ...
Jernigan Sarah C SC Department of - - 2014
Object The purpose of this study was to compare the effectiveness of CSF diversion with endoscopic third ventriculostomy (ETV) versus shunt therapy in infants with hydrocephalus. Methods The authors conducted a retrospective analysis of 5416 infants 1 year of age or younger with hydrocephalus (congenital or acquired) in whom CSF ...
Murthy Karna K Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. Electronic address: - - 2014
The optimal surgical approach in infants with gastroschisis (GS) is unknown. The purpose of this study was to estimate the association between staged closure and length of stay (LOS) in infants with GS. We used the Children's Hospital Neonatal Database to identify surviving infants with GS born ≥34weeks' gestation referred ...
Sampson Mario R MR From the *Duke Clinical Research Institute, Durham; †University of North Carolina, Eshelman School of Pharmacy, Chapel Hill, NC; ‡Wichita Medical Research and Education Foundation, Wichita, KS; §EMMES Corporation, Rockville, MD; and ¶University of California-San Diego, Schools of Medicine and Pharmacy, La Jolla, - - 2014
Acyclovir is used to treat herpes infections in preterm and term infants; however, the influence of maturation on drug disposition and dosing requirements is poorly characterized in this population. We administered intravenous acyclovir to preterm and term infants <31 days postnatal age and collected plasma samples. We performed a population ...
Park Jinhee J School of Nursing, The University of North Carolina at Chapel Hill School of - - 2014
Very preterm (VP, ≤30 wk gestational age) infants are at risk for impaired lung function, which significantly limits their ability to eat. A semielevated side-lying (ESL) position is a feeding strategy that may improve oral feeding by supporting breathing during feeding. The study evaluated the efficacy of the ESL position ...
Sutcliffe Catherine G CG Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of - - 2014
Early infant HIV diagnosis is challenging in sub-Saharan Africa, particularly in rural areas where laboratory capacity is limited. Specimens must be transported to central laboratories for testing, leading to delays in diagnosis and initiation of antiretroviral therapy. This study was undertaken in rural Zambia to measure the turnaround time for ...
Gorry Conner - - 2014
David, Daniel, and Diego were born at 32 weeks via caesarean section in Cuba's eastern province of Granma-they weighed between 1520 and 1780 grams each. Their mother, Dayanis Díaz, wasn't producing enough milk for her triplets and just 24 hours after birth, they were being fed with pasteurized milk from ...
Thoene Melissa M Newborn Intensive Care Unit, Nebraska Medical Center, Omaha, NE 68198, USA. - - 2014
The use of human milk fortifiers (HMF) helps to meet the high nutritional requirements of the human milk-fed premature infant. Previously available powdered products have not met the protein requirements of the preterm infant population and many neonatologists add powder protein modulars to help meet protein needs. The use of ...
Buchanan Ann M AM Kilimanjaro Christian Medical Centre, Moshi, Tanzania ; Division of Infectious Diseases, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, United States of America ; Duke Global Health Institute, Duke University, Durham, North Carolina, United States of - - 2014
Mother to child transmission (MTCT) of HIV-1 remains an important problem in sub-Saharan Africa where most new pediatric HIV-1 infections occur. Early infant diagnosis of HIV-1 using dried blood spot (DBS) PCR among exposed infants provides an opportunity to assess current MTCT rates. We conducted a retrospective data analysis on ...
Ahmad Syed Amir SA Department of Emergency Medicine, Pediatric Emergency, King Khalid University Hospital, King Saud University, Riyadh, Saudi - - 2014
Bronchiolitis is a self-limiting disease of children caused by viral infections of the small airways with a wide spectrum of illness severity. Search of the literature reveals a need for refinement of criteria for testing for concomitant severe bacterial infections as well as appropriate therapeutic interventions for patients <90-day-old diagnosed ...
Takahashi Mihoko M Department of Public Health, Faculty of Medicine, Saitama Medical - - 2014
Objectives To investigate the effect of determining birthdays by social factors on the distribution of daily live births.Methods We obtained data on live births tabulated by date and birthplace (hospitals, clinics, and maternity homes) between 1981 and 2010 in Japan from the National Vital Statistics System. This study analyzed the variations in ...
Ponrartana Skorn S Department of Radiology, Children's Hospital Los Angeles, Los Angeles, California, United States of - - 2014
The buccal fat pad (BFP) is an encapsulated mass of adipose tissue thought to enhance the sucking capabilities of the masticatory muscles during infancy. To date, no conclusive evidence has been provided as to the composition of the BFP in early postnatal life. The purpose of this study was to ...
Murray Joanna J Department of Primary Care and Public Health, Imperial College London, London, United - - 2014
To examine the timing and duration of RSV bronchiolitis hospital admission among term and preterm infants in England and to identify risk factors for bronchiolitis admission. A population-based birth cohort with follow-up to age 1 year, using the Hospital Episode Statistics database. 71 hospitals across England. We identified 296618 individual ...
Lund Marie M Department of Epidemiology Research, National Health Surveillance and Research, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, - - 2014
To assess the association between use of macrolide antibiotics in mothers and infants from pregnancy onset until 120 days after birth and infantile hypertrophic pyloric stenosis (IHPS). Nationwide register based cohort study. Denmark, 1996-2011. 999 378 liveborn singletons and linked individual level information on macrolide prescriptions (maternal use during pregnancy, n=30 091; ...
Chisholm Karen M KM Pathology and Laboratory Medicine Institute, Cleveland Clinic, 9500 Euclid Avenue, L21, Cleveland, OH 44195; phone: 216 444 5777; e mail: - - 2014
In our autopsy experience, abnormal erythroblast nuclear contours are frequently observed in the stillborn fetus or neonate without marrow failure disorders. Bone marrow and liver slides from autopsies of fetuses and infants less than six months of age were analyzed for the percent erythroblasts with nuclear irregularities, and correlated with ...
Ishibashi Hiroki H Department of Pediatric Surgery and Pediatric Endoscopic Surgery, Tokushima University - - 2014
Iliopsoas abscess (IPA) is uncommon in childhood and very rare in the neonate and infant. We present a case of IPA after an umbilical granuloma in an infant. A baby girl with a birth weight of 2,970 g was born at thirty-seven weeks and two days gestation by Caesarean Section. ...
Sargent Barbara B Division of Biokinesiology & Physical Therapy, University of Southern California, Los Angeles, California, United States of - - 2014
A critical issue in the study of infant development is to identify the processes by which task-specific action emerges from spontaneous movement. Emergent leg action has been studied by providing contingent reinforcement to specific leg movements using an overhead infant-activated mobile, however, there is limited information on the strategies used ...
Meszes Angéla A Department of Dermatology and Allergology, University of Szeged, Szeged, - - 2014
Wound care in neonates demands special awareness of the anatomical and physiological characteristics of their skin, and the danger of adverse mechanical and toxicological events. Here, we present the case of a full-term neonate born with myelomeningocele. Following the closing surgery on the 3rd day of postuterine life, the operated ...
Thorisdottir Birna B Unit for Nutrition Research, Landspitali University Hospital & Faculty of Food Science and Nutrition, School of Health Sciences, University of Iceland, Eiriksgata 29, IS-101 Reykjavik, Iceland. - - 2014
The objective was to assess the vitamin D status in healthy 12-month-old infants in relation to quantity and sources of dietary vitamin D, breastfeeding and seasons. Subjects were 76 12-month-old infants. Serum levels of 25-hydroxyvitamin D (25(OH)D) ≥ 50 nmol/L were considered indicative of vitamin D sufficiency and 25(OH)D < ...
Fusch Christoph C Department of Pediatrics, McMaster University & Hamilton Health Sciences, Hamilton, Ont., - - 2014
The sudden disruption of excessive placental supply with fluids and electrolytes is challenging for neonatal physiology during the period of postnatal adaptation. Different from many other nutrients, the body experiences large changes in daily requirements during the first 7-14 postnatal days, and on the other hand does not tolerate conditions ...
Erol Sara - - 2014
Nosocomial blood stream infections (NBSI) are a significant hazard in health care facilities, exacting a tremendous toll and causing increased morbidity, mortality, and increased length of hospital stay and health care costs. In this article, we report the results of a retrospective cohort study to describe the epidemiology of pseudomonas ...
Perisson Caroline C Department of Pediatric Pulmonology, Trousseau Children Hospital, Paris, - - 2014
A 3-month-old infant was admitted to the respiratory unit for dyspnoea and vomiting after her second DTaP-Polio vaccine shot. The chest X-rays showed a white right lung with a left mediastinal shift. A pleural aspiration assessed the diagnosis of chylothorax. A conservative treatment was initiated with a fat-free diet and ...
Sharma Deepak D Department of Neonatology, Fernandez Hospital, Hyderabad, Andhra Pradesh, - - 2014
A preterm male infant (35 weeks), appropriate for gestational age with birth weight of 2.20 kg was born to a 28-year G2 P0 mother. The mother's blood group was A positive and the father's was B positive. Her first pregnancy was an intrauterine fetal death due to immune hydrops. The ...
Papagaroufalis Konstantinos K Maternity Helena Venizelou, Athens, - - 2014
d-Lactic acidosis in infants fed lactic acid bacteria-containing products is a concern. The primary objective of this non-inferiority trial was to compare urinary d-lactic acid concentrations during the first 28 days of life in infants fed formula containing Lactobacillus reuteri (1.2 × 10(6) colony forming units (CFU)/ml) with those fed ...
Rai Birendra B Department of Pediatrics, Midland Regional Hospital, Mullingar, Westmeath, - - 2014
A male infant was born at 34 weeks' gestation to a primigravida mother. The mother had a history of 1 day of diarrhoea and mild fever 8 days prior to delivery. Her blood culture was negative during the illness and her stool did not grow any pathological organism. The baby had poor feeding ...
Sriram Sudhir S Department of Pediatrics, University of Chicago, 5841 South Maryland Avenue MC 6060, Chicago, IL 60637, - - 2014
Aim. To determine among infants born before the 28th week of gestation to what extent blood gas abnormalities during the first three postnatal days provide information about the risk of bronchopulmonary dysplasia (BPD). Methods. We studied the association of extreme quartiles of blood gas measurements (hypoxemia, hyperoxemia, hypocapnea, and hypercapnea) ...
Patelarou Evridiki E Florence Nightingale School of Nursing and Midwifery, King's College London, London SE18WA, UK. - - 2014
The purpose of this review was to summarize existing epidemiological evidence of the association between quantitative estimates of indoor air pollution and all-day personal exposure with adverse birth outcomes including fetal growth, prematurity and miscarriage. We carried out a systematic literature search of MEDLINE and EMBASE databases with the aim ...
Lukasse Mirjam M Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway; Department of Health, Nutrition and Management, Oslo and Akershus university college of applied sciences, Oslo, - - 2014
We sought to prospectively study the association between antenatal emotional distress and gestational length at birth as well as preterm birth. We followed up 40,077 primiparous women in the Norwegian Mother and Child Cohort Study. Emotional distress was reported in a short form of the Hopkins Symptom Checklist-25 (SCL-5) at ...
Geoghegan Sarah F SF Department of Neonatology, National Maternity Hospital, Dublin, - - 2014
A baby girl was delivered by emergency caesarean section at 23+6 weeks gestation weighing 440 g. Apgar scores were 1, 3 and 4 at 1, 5 and 10 min, respectively. She was intubated and transferred to the neonatal intensive care unit. Umbilical arterial and venous lines and an orogastric tube (OGT) were inserted. ...
Kanti V V Department of Dermatology and Allergy, Clinical Research Center for Hair and Skin Science, Charité-Universitätsmedizin Berlin, Berlin, - - 2014
In preterm infants, skin barrier maturation entails regional variability. To characterize postnatal skin barrier development in covered, uncovered and diapered regions in healthy premature infants over a longitudinal observation period. Transepidermal water loss (TEWL), stratum corneum hydration (SCH), pH and sebum were measured at postnatal ages of 1-7 days and ...
Aurpibul Linda L Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, - - 2014
Dengue is a mosquito-borne infection affecting children and adults worldwide. In newborn infants, the dengue virus can cause diseases, especially in infants born to pregnant women hospitalised with dengue or postpartum women with fever. The authors report a case of a term newborn infant who presented with haemodynamic instability and ...
Hoerning André A Department for Pediatric Nephrology, Gastroenterology, Endocrinology and Transplant Medicine, Clinic for Pediatrics II, University Children's Hospital Essen, University Duisburg-Essen , Essen , Germany ; Department of Pediatrics and Adolescent Medicine, University Children's Hospital Erlangen, Friedrich-Alexander University , Erlangen , - - 2014
Rapidly establishing the cause of neonatal cholestasis is an urgent matter. The aim of this study was to report on the prevalence and mortality of the diverse disorders causing neonatal cholestasis in an academic center in Germany. Clinical chemistry and cause of disease were retrospectively analyzed in 82 infants (male ...
Kantake Masato M Perinatal Medical Center, Juntendo University Urayasu Hospital, Urayasu, Chiba, - - 2014
To examine the environmental effects on cytosine methylation of preterm infant's DNA, because early life experiences are considered to influence the physiological and mental health of an individual through epigenetic modification of DNA. A prospective cohort study, comparison of epigenetic differences in the glucocorticoid receptor (GR) gene between healthy term ...
Dyson Rebecca M RM Mothers and Babies Research Centre, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia; Discipline of Paediatrics and Child Health, School of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia; Illawarra Health and Medical Research Institute and Graduate School of Medicine, University of Wollongong, Wollongong, NSW, - - 2014
Excessive vasodilatation during the perinatal period is associated with cardiorespiratory instability in preterm neonates. Little evidence of the mechanisms controlling microvascular tone during circulatory transition exists. We hypothesised that hydrogen sulphide (H2S), an important regulator of microvascular reactivity and central cardiac function in adults and animal models, may contribute to ...
Mourani Peter M PM Pediatric Heart Lung Center, University of Colorado School of Medicine/Children's Hospital Colorado, Aurora, CO. Electronic address: - - 2013
To determine the incidence and risk factors for readmission to the intensive care unit (ICU) among preterm infants who required mechanical ventilation at birth. We studied preterm newborns (birth weight 500-1250 g) who required mechanical ventilation at birth and were enrolled in a multicenter trial of inhaled nitric oxide therapy. ...
Fleddermann Manja M Dr. von Hauner Children's Hospital, University of Munich Medical Centre, Munich, - - 2013
Protein source, macronutrient composition and content of long chain-polyunsaturated fatty acids (LC-PUFA) of infant formulae may influence infant growth. We aimed to assess the effect of a modified infant formula on growth. In a randomized, double-blind trial, 213 healthy term infants consumed isoenergetic study formulae (intervention formula - IF, control ...
Swann Olivia O aUniversity of Malawi College of Medicine, Blantyre, Malawi bCentre for Immunity, Infection and Evolution, Edinburgh, UK cMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi dUniversity of Liverpool, Liverpool, UK eTownsville Hospital, Douglas, Queensland, Australia fUniversity of Edinburgh, Edinburgh, UK gLiverpool School of Tropical Medicine, Liverpool, - - 2013
Neonatal meningitis is an important cause of morbidity in sub-Saharan Africa and requires urgent empiric treatment with parenteral administered antibiotics. Here we describe the etiology, antimicrobial susceptibility and suitability of the World Health Organization (WHO) first-line recommended antibiotics (penicillin and gentamicin) for bacterial meningitis in young infants in Malawi. We ...
Slusher Tina M - - 2013
Severe neonatal jaundice and its progression to kernicterus is a leading cause of death and disability among newborns in poorly-resourced countries, particularly in sub-Saharan Africa. The standard treatment for jaundice using conventional phototherapy (CPT) with electric artificial blue light sources is often hampered by the lack of (functional) CPT devices ...
Quach Caroline C Division of Infection Control, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, - - 2014
Background. Despite implementation of recommended best practices, our central line-associated bloodstream infection (CLABSI) rates remained high. Our objective was to describe the impact of chlorhexidine gluconate (CHG) bathing on CLABSI rates in neonates. Methods. Infants with a central venous catheter (CVC) admitted to the neonatal intensive care unit from April 2009 to ...
Vesoulis Zachary A ZA Department of Pediatrics, Washington University School of Medicine, St. Louis, - - 2013
Background:Previous studies of very preterm (VPT) infants have shown a wide range of seizure prevalence and association with intraventricular hemorrhage (IVH), white matter injury (WMI) and death. However, the impact of seizures on neurodevelopment is not well known. We hypothesized that seizures in the first three days after VPT birth ...
Helfer Sven S Department of Pediatric Cardiology, Charité University Medical Center, Berlin, - - 2013
Preterm infants may have cardiac stress related to patent ductus arteriosus (PDA) or bronchopulmonary dysplasia (BPD). In this study, we examined the development of cardiac function in preterm infants by measuring tissue Doppler-derived peak systolic strain (PSS) and strain rate (PSSR) in the first 28 days of life. Peak systolic strain ...
van Sorge Arlette J AJ Department of Ophthalmology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: - - 2013
To study the incidence and risk factors for retinopathy of prematurity (ROP) in the Netherlands. Prospective, approximating population-based study that included infants with gestational age (GA) <32 weeks and/or birth weight (BW) <1500 g born in 2009. Pediatricians and ophthalmologists of all hospitals involved in care for premature infants reported ...
Schmiedchen Bettina B Department of Physiology and Pathophysiology, University of Potsdam, Nuthetal, - - 2013
Background: The relative dose response (RDR) test, which quantifies the increase in serum retinol after vitamin A administration, is a qualitative measure of liver vitamin A stores. Particularly in preterm infants, the feasibility of the RDR test involving blood is critically dependent on small sample volumes. Objectives: This study aimed ...
Vergales Brooke D BD Division of Neonatology, Department of Pediatrics, University of Virginia, Charlottesville, - - 2013
Objective Asphyxia can lead to autonomic nervous system dysfunction, including depressed heart rate variability (HRV). We tested the hypothesis that low HRV is associated with adverse short-term outcomes of abnormalities on electroencephalogram (EEG) and brain magnetic resonance imaging (MRI) and death in neonates with hypoxic ischemic encephalopathy (HIE). Study Design Neonates undergoing ...
Adam Ryan J RJ 1 Department of Internal - - 2013
Air trapping and airflow obstruction are being increasingly identified in infants with cystic fibrosis. These findings are commonly attributed to airway infection, inflammation, and mucus buildup. To learn if air trapping and airflow obstruction are present before the onset of airway infection and inflammation in cystic fibrosis. On the day ...
Kasapkara Ciğdem Seher CS Pediatric Metabolic Unit - - 2013
Abstract Neonatal-onset propionic acidemia (PA), the most common form, is characterized by poor feeding, vomiting, and somnolence in the first days of life in a previously healthy infant, followed by lethargy, seizures, and can progress to coma if not identified and treated appropriately. It is frequently accompanied by metabolic acidosis ...
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