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Walker M W MW Division of Neonatology, Children's Hospital, Greenville Health System, Greenville, SC, - - 2014
Objective:The primary aim of the study was to determine how the risk of adverse outcomes was related to the duration of the latency period and gestational age at birth following preterm premature rupture of the fetal membranes (PPROM).Study Design:Retrospective review of infants discharged from 330 neonatal intensive care units. We ...
Tsai Wen-Hui WH Institute of Clinical Medicine, National Cheng Kung University College of Medicine, Tainan 701, Taiwan; Division of Neonatology, Chi Mei Medical Center, Tainan 710, - - 2014
Mechanical ventilation for preterm infants independently contributes to poor neurodevelopmental performance. However, few studies have investigated the association between the duration of mechanical ventilation and the risk for various developmental disorders in extremely low birth weight (ELBW) (<1000g) infants. Using a large nationwide database, we did a 10-year retrospective follow-up ...
Cetinkaya Merih M Department of Neonatology, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey. Electronic address: - - 2014
sE-selectin has recently been suggested as a surrogate marker for prediction of ROP development. The possible role of serial plasma sE-selectin measurements in early prediction and diagnosis of ROP was evaluated. Prospective observational study SUBJECTS: Forty six preterm infants aged <34weeks of gestation and weighing <1500 g were enrolled. Of ...
Marinelli Kathleen A KA 1The Connecticut Human Milk Research Center, Hartford, CT, - - 2014
Background:Use of donor milk (DM) to supplement mother's own milk (MOM) in the neonatal intensive care unit (NICU) is steadily increasing based on health and developmental benefits to premature infants. A paucity of data exists documenting the effect of DM use on the diet of very low birth weight (VLBW) ...
McCormick Michael E ME Division of Pediatric Otolaryngology, Medical College of Wisconsin and Children's Hospital of Washington, Milwaukee, - - 2014
Importance: We describe management of an infant with chronic aspiration as a result of severe and rarely-described laryngeal dysgenesis. Observations: A neonate with severe maldevelopment of the laryngeal structures required tracheostomy for respiratory distress on day-of-life one, but the patient continued to have aspiration pneumonias. After failing to improve with ...
Wong Jonathan J Department of Pediatrics, Kingston General Hospital, Kingston, Ontario, - - 2014
Objective To compare neonatal outcomes between infants who received inotropes and those who did not, and identify variation in inotrope use. Study Design Retrospective review of data from neonates < 29 weeks gestation collected by the Canadian Neonatal Network during 2003 to 2010. After controlling for confounders and maternal/infant characteristics, rates of mortality and ...
Fernández C L A CL Instituto Nacional de Perinatología, - - 2014
Objective:To compare the incidence of oxygen dependency in SIBEN neonatal units while adjusting for altitude.Study Design:We reviewed the charts of infants who were1500 g at birth, admitted to six neonatal intensive care units (NICUs) near sea level and in seven NICUs at varying altitudes above sea level from the SIBEN network ...
Ichinomiya Kenji K Department of Neonatology, Gunma Children's Medical Center, 779 Shimohakoda, Hokkitsu, Shibukawa, Gunma 377-8577, - - 2014
Despite the early use of phototherapy and exchange transfusion in premature infants based on their levels of total serum bilirubin (TSB), the reemergence of kernicterus has been reported. The purpose of this study was to assess the validity of using TSB levels as the criterion for phototherapy in extremely-low-birth-weight infants ...
Gaballah Marian M Department of Radiology, Children's Hospital of Philadelphia, Perelman School of Medicine of the University of Pennsylvania, 3401 Civic Center Blvd., Philadelphia, PA 19104. Electronic address: - - 2014
To describe experience with the use of ultrasound (US)-guided placement and tip position confirmation for direct saphenous and single-incision tunneled femoral noncuffed central venous catheters (CVCs) placed in neonates and infants at the bedside. A retrospective review of the interventional radiology (IR) database and electronic medical records was performed for ...
Lasekan John B JB a Pediatric Nutrition R&D, Abbott Nutrition, Abbott Laboratories , Columbus , - - 2014
Objective: Spit-up (regurgitation) reduction with prethickened milk protein-based infant formulas containing rice starch has been clinically demonstrated in infants with heavy spit-ups but not in otherwise healthy normal infants with common spit-ups. The objective of this study was to evaluate growth, gastrointestinal tolerance, and efficacy to reduce common spit-up in ...
Ansary A A Department of Neonatology, Royal Hospital for Sick Children (Yorkhill), Dalnair Street, Glasgow G3 8SJ, United Kingdom. - - 2014
Venlafaxine, a serotonin and norepinephrine reuptake inhibitor, is increasingly used in pregnant women with pre-existing depression who require continued treatment. However, its in uteroeffects on the developing fetus are not clear. Herein, we report the unusual presentation of venlafaxine withdrawal in a female preterm baby of 29 weeks gestation, who ...
Ruiz-Rodriguez S S Pediatric Dentistry Posgraduate Program, Facultad de - - 2014
Objective: To investigate the possible association between maternal S. mutans levels and those of the infant during the period between birth and 5 months and evaluate possible risk factors in the S mutans colonization. Study Design: A prospective cohort study was carried out comprising 62 infants and their mothers, selected ...
Aunsholt Lise L Hans Christian Andersen Children's Hospital, Odense University Hospital, Odense, - - 2014
Background: Necrotizing enterocolitis and congenital gastrointestinal malformations in infants often require intestinal resection, with a subsequent risk of short bowel syndrome (SBS). We hypothesized that immediate intestinal adaptation following resection of the distal intestine with placement of a jejunostomy differs between preterm and term neonates. Methods: Preterm or term piglets ...
Berger Jessica J Division of Perinatal Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, - - 2014
Objective The objective of this study was to assess rates of bronchopulmonary dysplasia (BPD) and BPD/death in infants first extubated between day of life (DOL) 1 to 3 versus 4 to 7, 8 + , and impact of reintubation. Study Design We included infants with gestational age ≤ 28 weeks, birth weight ≤ 1,000 g, and intubation ...
Tubbs-Cooley Heather L HL Research in Patient Services, Division of Nursing, Cincinnati Children's Hospital Medical Center, Cincinnati, - - 2014
Objective To examine the association of missed oral feeding opportunities among preterm infants with achievement of full oral feedings and length of hospitalization. Study Design A secondary analysis of clinical trial data was conducted. Study infants included in the analysis (N = 89) were randomized to one of four standardized feeding progression approaches; detailed ...
Jeziorsky Eric E Department of Pediatrics, Montpellier University Hospital, Montpellier, France; INSERM U1058, Montpellier 1 University, Montpellier, - - 2014
The human parechoviruses (HPeVs) were recently recognized as important viral pathogens involved in various illnesses in young children. However, routine detection is not performed in most clinical laboratories. Therefore, in this study, we aim to assess the relevance of HPeV detection in cerebrospinal fluid (CSF) of infants, according to clinical ...
Besançon Alix A A Besançon, Endocrinologie-Diabétologie-Gynécologie Pédiatrique, Hopital Necker, PARIS, - - 2014
Hyperthyroidism in neonates born to mothers with Graves' disease (GD) can be associated with significant morbidity and mortality but is still overlooked by clinicians. Management of neonatal hyperthyroidism would be improved by a better understanding of the predictive factors involved. The aim of this study was to evaluate the course ...
Borschel Marlene W MW 1Abbott Nutrition, Abbott Laboratories, Columbus, OH, - - 2014
Extensively hydrolyzed formulas present a complex matrix subject to adverse conditions during manufacture that could influence growth and tolerance of infants fed these formulas. A masked, randomized, parallel growth study was conducted in infants fed a ready-to-feed (RTF) or powdered (PWD) form of an extensively hydrolyzed casein-based formula. Infants were ...
Senniappan Senthil S From the Developmental Endocrinology Research Group, Clinical and Molecular Genetics Unit, Institute of Child Health, University College London (S.S., P.S., V.A., K.H.), and the Departments of Paediatric Endocrinology (S.S., P.S., V.A., K.H.) and Histopathology (D.P., M.A.), Great Ormond Street Hospital for Children, London, and the Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter (S.F., S.E.) - all in the United Kingdom; the Department of Pathology, University of California, San Francisco, San Francisco (S.A.); and the Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, Houston (N.T., - - 2014
Hyperinsulinemic hypoglycemia is the most common cause of severe, persistent neonatal hypoglycemia. The treatment of hyperinsulinemic hypoglycemia that is unresponsive to diazoxide is subtotal pancreatectomy. We examined the effectiveness of the mammalian target of rapamycin (mTOR) inhibitor sirolimus in four infants with severe hyperinsulinemic hypoglycemia that had been unresponsive to ...
Bender Jeffrey M JM Department of Pediatrics, Kaiser Permanente, Los Angeles Medical Center, Los Angeles, California; Division of Pediatric Infectious Diseases, Department of Pediatrics, Children's Hospital Los Angeles, Los Angeles, - - 2014
Human rhinovirus (HRV) is a common cause of respiratory illness in children. The impact of HRV infection on 1- to 90-day-old infants is unclear. We hypothesized that HRV infection would be clinically similar to respiratory syncytial virus (RSV) infection in the hospitalized infants. We conducted a retrospective study of hospitalized ...
Wei Yi-Hsuan YH Division of Neonatology, Department of Pediatric, Changhua Christian Hospital, Changhua, - - 2014
Pneumothorax is more frequent in the neonatal period, especially among premature infants. Pigtail catheters have been shown to be as effective as and less invasive than traditional chest tubes in adults; however, data regarding premature infants are limited. We aimed to compare the efficacy, safety, and complications associated with the ...
De Jong Grant D GD Ecological Division, GEI Consultants Inc., Denver, CO, - - 2014
Urogenital myiasis of newborn infants, although rare, is usually considered to indicate neglect due to attraction of flies to feces; however, infant feces have not been determined to attract insects. Human meconium and breast-fed-infant feces were used to determine attractiveness to insects and to examine subsequent colonization and growth patterns ...
Kuban Karl C K KC 1Department of Pediatrics, Boston Medical Center, Boston, MA, - - 2014
The authors hypothesized that among extremely preterm infants, elevated concentrations of inflammation-related proteins in neonatal blood are associated with cerebral palsy at 24 months. In 939 infants born before 28 weeks gestation, the authors measured blood concentrations of 25 proteins on postnatal days 1, 7, and 14 and evaluated associations ...
Garofoli Francesca F Neonatal Immunology Laboratory, Neonatal Unit and Neonatal Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo , Pavia , Italy - - 2014
Abstract Forty breastfed full-term infants were randomly, double blind assigned to receive orally Lactobacillus reuteri (L. reuteri) DSM 17938, 5 drops/daily (10(8) colony-forming units), for 4 weeks (n = 20) or an identical placebo (n = 20), starting before third day of life. They underwent basal and final visit to monitor growth parameters and ...
Baxi Anand C AC Division of Pediatric Cardiology, Sibley Heart Center, Children's Healthcare of Atlanta, Emory University School of Medicine, 1405 Clifton Road, NE, Atlanta, GA, 30322-1062, USA, - - 2014
Necrotizing enterocolitis (NEC) is a rare but catastrophic complication that may occur in newborns with congenital heart disease (CHD). In the preterm population, transfusion of red blood cells (RBCs) and use of RBCs with longer storage time have been independently associated with the development of NEC. To date, it is ...
Smirk Cameron L CL Newborn Services, Parkville, Victoria, - - 2014
Neonatal abstinence syndrome (NAS) is an increasingly common disorder diagnosed in infants exposed to various drugs, causing immense financial and social burden. Recommendations from various bodies are for babies to be monitored for 4 to 7 days following birth so that prompt treatment can commence should symptoms develop. We aimed ...
Escamilla-Nuñez María Consuelo - - 2014
Prenatal consumption of omega-3 fatty acids can act as an adjuvant in the development of the immune system and affect the inflammatory response of neonates. We conducted a double-blind, randomized, placebo-controlled trial in Cuernavaca, Mexico. We randomly assigned 1,094 pregnant women (18 to 35 years of age) to receive 400 ...
Jonsdottir Olof H OH 1 Unit for Nutrition Research, Landspitali, The National University Hospital of Iceland and Faculty of Food Science and Nutrition, School of Health Sciences, University of Iceland , Reykjavik, Iceland - - 2014
Abstract Introduction: Breastfeeding has several advantages for both mother and child. Lactation consultants may promote prolonged breastfeeding, but little is known about their impact on the initiation of complementary feeding. Subjects and Methods: Dietary intake during the initial complementary feeding period from 5 to 6 months was collected on mother-infant ...
Testoni Daniela D From the * Duke Clinical Research Institute, Durham, NC; † Department of Pediatrics, Duke University, Durham, NC; ‡ Pediatrix-Obstetrix Center for Research and Education, Sunrise, FL; § Division of Neonatal Medicine, Escola Paulista de Medicina - Universidade Federal de São Paulo, São Paulo, Brazil; ¶ Department of Economics, Clemson University, Clemson, - - 2014
The epidemiology and incidence of late-onset bloodstream infections (BSIs) in premature infants has been described, but studies describing late-onset BSI in term infants are sparse. We sought to describe the pathogens, incidence, risk factors, and mortality of late-onset BSI in hospitalized term infants. A cohort study was conducted of infants ...
Cohen-Wolkowiez Michael M Department of Pediatrics, Duke University, Durham, - - 2014
Piperacillin-tazobactam is often given to infants with severe infection in spite of limited pharmacokinetics (PK) data. We evaluated piperacillin-tazobactam PK in premature and term infants aged <61 days with suspected systemic infection. Infants received intravenous piperacillin-tazobactam (80-100 mg/kg q 8hrs) based on gestational and postnatal age. Sparse plasma samples were ...
Malkar Manish B MB Department of Pediatrics, Division of Neonatology, Nationwide Children's Hospital, The Ohio State University, Columbus, - - 2014
We tested the hypothesis that Respiratory Severity Score (RSS) on day of life 30 is predictive of mortality and length of mechanical ventilation in premature infants on prolonged mechanical ventilation. A retrospective chart review was performed using the Nationwide Children's Hospital medical record and Vermont-Oxford Network databases. The primary outcome ...
Natalucci Giancarlo G 1] Department of Neonatology, Zurich University Hospital, 8091 Zurich, Switzerland [2] Child Development Centre, Zurich University Children's Hospital, 8032 Zurich, - - 2014
Background:Amplitude-integrated electroencephalogram (aEEG) is increasingly used for neuromonitoring in preterms. We aimed to quantify the effects of gestational age (GA), postnatal age (PNA), and other perinatal factors on the development of aEEG early after birth in very preterm newborns with normal cerebral ultrasounds.Methods:Continuous aEEG was prospectively performed in 96 newborns ...
Schumacher E M EM Faculty of Medicine, University of Oslo, Oslo, - - 2014
Background: Spectral EEG analysis using automated quantification of total absolute band power (tABP) expresses brain function. We hypothesized that pCO2 or blood glucose affects tABP during the critical first days of life in premature infants. Objective: To use automated tABP quantification to determine whether EEG background activity in premature infants ...
Nestaas Eirik E Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway; Department of Paediatrics, Vestfold Hospital Trust, Norway. Electronic address: - - 2014
Therapeutic hypothermia has become standard treatment for moderate and severe neonatal hypoxic-ischemic encephalopathy (HIE) to reduce cerebral morbidity and mortality. The effect on the heart is incompletely explored. To assess the myocardial function during and after whole-body therapeutic hypothermia for HIE. Observational cohort study. Forty-four infants with HIE cooled for ...
Hamilton Emily E Division of Neonatology, Department of Pediatrics, Medical University of South Carolina, Charleston, SC, United States. Electronic address: - - 2014
Debate exists about when to initiate enteral feeding (EF) in very low birth weight (VLBW) preterm infants. This retrospective study compared the effectiveness of an education-based quality improvement project and the relationship of time of the first EF to necrotizing enterocolitis (NEC) or death incidence and parenteral nutrition (PN) days ...
Toyama Noriko N Department of Human Environmental Sciences, Faculty of Human Sciences, Waseda University, Mikajima 2-579-15, Tokorozawa, SAITAMA, 359-1192, Japan. Electronic address: - - 2014
During the weaning period, infants are not skilled at self-feeding and caregivers play a prominent role in feeding. Solid feeding is therefore an inherently collaborative and interactive process between infants and caregivers. The present study examined how caregivers and infants coordinate their solid feeding interactions, based on naturalistic longitudinal observations ...
Herrmann Kenneth K 1 Department of Pediatrics, Indiana University School of Medicine , Indianapolis, - - 2014
Abstract Objective: This study tested the hypothesis that feeding an exclusively human milk (EHM) diet to premature infants reduces the incidence of necrotizing enterocolitis (NEC) associated with enteral feeding. Study Design: An observational study for infants born at less than 33 weeks of gestational age was performed in a single ...
Cizmeci Mehmet Nevzat - - 2014
To investigate the characteristic features of transient neonatal feeding intolerance (TNFI) during the hospitalization for birth in the maternity ward. A prospective follow-up study. Maternity ward and neonatal intensive care unit (NICU) in an academic medical center. Term (≥ 37-weeks gestation) infants admitted to the neonatal intensive care unit with ...
Queiroz Thais Costa Nascentes TC Departamento de Gastroenterologia Pediátrica, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, - - 2014
Context Biliary atresia is a progressive, idiopathic, fibro-obliterative disease of the extrahepatic biliary tree that pre-sents with biliary obstruction exclusively in the neonatal period. Objectives To assess the differences regarding age at referral, age at surgery, duration of propaedeutics and waiting time for surgery between two groups of infants in ...
Do Hyun Jeong HJ Department of Pediatrics, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, - - 2014
Neonatal late-onset hypocalcemia is defined as hypocalcemia developed after postnatal 3 days and associated with hypoparathyroidism, high phosphate diets and vitamin D deficiency. We experienced the increment of neonatal late onset hypocalcemia over 1 year. We tried to evaluate the relationship between late onset hypocalcemia and maternal hypovitaminosis D. The ...
Natu Sanjay A SA Associate Professor, Department of Paediatrics, Smt Kashibai Navale Medical College , Pune, India - - 2014
Haemophagocytic lymphohistiocytosis (HLH) is a potentially fatal, hyper inflammatory condition which is caused by a highly stimulated but ineffective immune response. We are presenting here, a case of HLH which occurred in a 45 day infant. Presence of lung cavity and a lytic bone lesion in the skull, as was ...
Tabel Yılmaz Y Department of Pediatric Nephrology, Faculty of Medicine, University of Inonu, Malatya, - - 2014
The aim of this prospective study was to evaluate urinary glutathione S transferases π (GST-π), beta-2-microglobulin (B2-MG), and N-acetyl-β-d-glucosaminidase (NAG) levels as markers revealing the effect of respiratory distress syndrome (RDS) on renal function in preterm infants. The study was performed with 76 preterm infants whose gestational ages were between ...
Tillman Emma M EM 1Department of Clinical Pharmacy, University of Tennessee Health Science Center, Memphis, - - 2014
Background: In 2009, an intestinal rehabilitation team implemented feeding guidelines for infants following gastrointestinal surgery at our institution. The purpose of this study was to determine the effect of enteral feeding guidelines on the incidence of parenteral nutrition (PN)-associated liver disease (PNALD) in infants with surgically managed necrotizing enterocolitis (NEC). ...
Cantey Joseph B JB Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX. Electronic address: - - 2014
In 2012, pertussis outbreak in a Dallas county resulted in the deaths of 4 children (3, unvaccinated; 2, <60 days of age). Despite recommendations that include immunization of women preferably during the third trimester of pregnancy or postpartum, household contacts ("cocooning"), and infants as early as 42 days of age, ...
Tsai A J AJ Division of Neonatology, Department of Pediatrics, University of Texas Medical School at Houston, Houston, TX, - - 2014
Objective:To determine which neuroimaging, clinical and sociodemographic factors predict neurodevelopment at 18-22 months age among extremely preterm infants with intraparenchymal hemorrhage (IPH).Study Design:Cranial ultrasounds performed before 42 days of age and cranial ultrasounds/magnetic resonance images of the brain performed near discharge were reviewed for hemorrhage location and other abnormalities. Clinical ...
Harmon Jeffrey J University of Cincinnati College of Medicine, Office of Student Affairs, Medical Sciences Building E-251, PO Box 670552, Cincinnati, OH 45267, United - - 2014
This series of three patients is the first description of the presentation, clinical course, and endoscopic findings of nasogastric tube-related airway distress, or nasogastric tube syndrome, in infants. We identify key differences in disease features from those described in adults, based on our literature review. Specifically, infant nasogastric tube syndrome ...
Bigger H R HR Rush University Medical Center, Chicago, IL, - - 2014
Objective:The objective of this study was to compare the currently used human milk (HM) quality indicators that measure whether very low-birthweight (VLBW; <1500 g birthweight) infants 'ever' received HM and whether they were still receiving HM at discharge from the neonatal intensive care unit (NICU) to the actual amount and timing ...
Greenwood Corryn C Perinatal Institute, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH; Division of Neonatology, Advocate Children's Hospital, Oak Lawn, - - 2014
To determine the impact of empiric ampicillin and gentamicin use in the first week of life on microbial colonization and diversity in preterm infants. The 16s ribosomal DNA community profiling was used to compare the microbiota of 74 infants born ≤32 weeks gestational age by degree of antibiotic use in ...
Wright Tiffany T University of Michigan, Ann Arbor, - - 2014
Long-term pulmonary outcomes of congenital diaphragmatic hernia (CDH) have demonstrated airflow obstruction in later childhood. We examined pulmonary function data to assess what factors predict lung function in the first three years of life in children with CDH. This was a retrospective study of patients treated for CDH who underwent ...
Shibasaki Jun J Department of Neonatology, Kanagawa Children's Medical Center, Yokohama City, Kanagawa, Japan. Electronic address: - - 2014
To investigate the use of indocyanine green (ICG) lymphography in the diagnosis and assessment of the severity of lymphatic dysfunction in infants and neonates with congenital lymphatic pleural effusion and ascites. We performed ICG lymphography on 10 neonates and infants with congenital lymphatic pleural effusion and ascites. After the subcutaneous ...
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