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Cady E B - - 1983
Intracellular metabolism in the brains of seven infants, born at 33-40 weeks' gestation and aged 44 h to 17 days, was studied on fourteen occasions by phosphorus nuclear magnetic resonance spectroscopy (31P NMRS). The characteristic spectral peaks of ATP, phosphocreatine (PCr), phosphodiesters, and inorganic orthophosphate (Pi) were always detected, together ...
Fenichel G M - - 1983
Many term newborns suffer some degree of perinatal asphyxia, but few become permanently brain damaged as a consequence, The newborns at risk for major neurologic handicaps have evidence of derangement in many organs, depressed cerebral function at birth that continues for days or weeks, and in many cases, convulsions soon ...
El-Tatawy S - - 1983
Twenty-two normal preterm and 10 full-term infants were studied by cranial computed tomography. The study included correlation of the gestational age and birth weight to the ventricular size, brain size, and the area of the sylvian fissure. The most relevant parameters were the bifrontal diameter, bifrontal index, and the transverse ...
El-Tatawy S - - 1983
Central nervous system manifestations are common in infants suffering from protein energy malnutrition. Computed tomography was used to search for pathology in the brain that might explain these symptoms. Subjects were 40 infants with protein malnutrition. All had mental symptoms. The bifrontal index was taken as the best parameter for ...
Brandom B W - - 1983
We measured uptake of halothane (the fraction of halothane in expired gas divided by the fraction of halothane in inspired gas, FE/FI) with a mass spectrometer over time in 7 infants less than 3 months of age. FE/FI for halothane in these infants increased more rapidly than has been described ...
Doyle L W - - 1983
The new diagnostic technique, positron emission tomography with 18F-2-fluoro-2-deoxy-D-glucose (18FDG), was used to measure regional cerebral glucose metabolism in five newborn infants with demonstrated structural abnormalities of the brain. 18FDG was synthesized, diluted in normal saline and injected intravenously. After one hour, tomographic slices of the brain were obtained, the ...
Fuller P W - - 1983
This study aimed at providing understanding of the etiology and mechanisms responsible for the learning and behavioral disabilities in the increasing numbers of survivors of neonatal intensive care units who develop MBD/LD-type (minimal brain dysfunction, learning disabilities) complications. The brains of 16 premature infants who died within the first month ...
Pallis C - - 1983
Four main areas generating confusion in discussion on brain death are identified as a) the relation of criteria of death to concepts of death, b) the argument about whether death is an event or a process, c) the inadequate differentiation of different neurological entities having different cardiac prognoses, and d) ...
Davies J E - - 1983
One percent lindane, widely used to treat scabies and pediculosis, presents toxicologic problems when used excessively. A 16-year-old mentally retarded boy accidentally ingested approximately 392 g of 1% lindane shampoo and recovered. A 2-month-old, 4.5-kg, male infant was found dead in his crib after excessive application of a 1% lindane ...
Horbar J D - - 1983
Sonography was used to investigate left-right asymmetries of the brain in 66 human neonates with gestational ages of 28-44 wk. The body of the left lateral ventricle was larger than the right in 21 infants (31.8%), whereas the right was larger than the left in only four infants (6.1%)(p less ...
Matsumoto N - - 1983
We have used brain ultrasonography in diagnosing and following up two infants, one with herpes simplex encephalitis and the other with cytomegalic inclusion disease. It was found that this technique was very useful to observe the changes of the brain parenchyma such as cystic degeneration and periventricular calcification. Also because ...
Voigt J - - 1983
Medico-legal data are presented on 995 child deaths, 361 girls and 634 boys aged 0-18 years, whose brains were weighed at the time of autopsy using a standardized weighing technique (the brains were weighed before fixation, immediately after entire removal; the medulla oblongata was divided in the foramen magnum). From ...
Halpern-Sebold L R - - 1983
We have traced the development from birth to puberty of the ir-LHRH producing centers, the nucleus olfactoretinalis (NOR), nucleus praeopticus periventricularis (NPP) and nucleus lateralis tuberis pars posterior (NLT), in male sibling platyfish genetically determined by differing P alleles to mature at two different ages. In sexually immature fish of ...
Davidson R J - - 1982
Ten-month-old infants viewed videotape segments of an actress spontaneously generating a happy or sad facial expression. Brain activity was recorded from the left and right frontal and parietal scalp regions. In two studies, infants showed greater activation of the left frontal than of the right frontal area in response to ...
Weber B A - - 1982
Two investigations were conducted in an attempt to devise an improved set of auditory brain stem response (ABR) latency norms for premature infants. The first study utilized the responses of 130 infants to develop conventional ABR wave V latency norms for different conceptual ages. In addition, three sets of alternative ...
Moskowitz R - - 1982
A 7-week-old male infant with a seizure disorder and an extensive sebaceous nevus of the scalp was examined. Computerized axial tomography (CAT) scan identified an intracerebral mass which proved to be a hamartomatous malofrmation fo the brain. The association of intracranial masses with sebaceous nevi should be recognized. CAT scan ...
Gilbert F F - - 1982
Monitoring of EEG, EKG and overt behavior of mink, muskrat, and beaver caught in leg hold traps in an aquatic tank, showed marked differences by species. Death by CO2 induced narcosis (submersion asphyxia) was evident in beaver, about 50 percent of muskrat but "wet" drowning occurred in mink. Bradycardia was ...
Shepard M - - 1982
Biparietal diameter measurement is the most widely accepted means of determining gestational age. However, a standard anatomic plane for performing this measurement has not been established. Three hundred forty-four measurements on 256 patients who gave birth to normal infants were obtained and compared at various cranial levels based on brain ...
Wilson E R - - 1982
Neuropathologic findings and clinical features of three patients with congenital brain stem damage are reported. All of the infants were premature (32 - 36 weeks' gestation) and experienced respiratory difficulty in the immediate postnatal period. One infant was moribund at deliver, dying 3 h after birth. In two infants who ...
Thorburn R J - - 1982
Comparisons were made in 69 newborn infants of the appearance of the brain as visualised by linear-array real-time ultrasound, computerised tomography and at autopsy, in order to evaluate the accuracy of ultrasound for the detection of lesions in the brain. Ultrasound was found to give a good estimate of the ...
Yoshioka T - - 1982
The excessive accumulation of lipoperoxides has been accepted as being highly responsible for the development of retinopathy of prematurity and idiopathic respiratory distress syndrome of the newborn infant. We have studied development-related levels of lipoperoxides in blood and tissues such as the liver, lungs, kidneys and brain from birth to ...
Grunnet M L - - 1981
We examined the brains of seven unrelated infants with Potter syndrome (oligohydramnios tetrad), a lethal neonatal disorder characterized by abnormal facies, lung hypoplasia, limb deformities, and classically, renal agenesis. All infants had defects of neuronal migration. The brains were small for gestational age in five of seven infants, and in ...
Thurston J H - - 1981
Infant mice (2 to 4 days old) received valproate (100 or 200 mg per kilogram body weight) subcutaneously once daily for 5 days. Both dosages decreased plasma beta-hydroxybutyrate levels to about one-third of the control value, in the face of normal free fatty acid and glycerol levels. At 200 mg ...
Goodwin L S - - 1981
A total of 120 computed tomographic scans of the brain in premature and full-term infants were reviewed. Of these, 28 were judged to exhibit normal ventricular dimensions, and the bifrontal, bicaudate, and bioccipital indices of the lateral ventricles were determined. The bifrontal and bicaudate indices followed a Gaussian distribution, with ...
Briner S - - 1981
Four asymptomatic infants with macrocrania, abnormal transillumination, and characteristic computed tomography scans are described. All had bilateral subdural collections, normal brain size, modest ventricular enlargement, and prominent cerebral sulci and interhemispheric fissures. Although these latter findings are often interpreted as atrophy, these infants had normal development and rapidly growing heads. ...
Murakami R - - 1981
Follow up study was conducted by brain CT scans on fullterm and premature infants for a period of 3 years following birth. The results were: 1. Low density areas were observed symmetrically in the frontal region in premature infants for 3 to 4 months after birth. However, they disappeared after ...
Shewmon D A - - 1981
One to 2 weeks after severe brain ischemia, four infants developed an unusual vascular lesion with a characteristic appearance on computed tomography that has not been reported previously. Restricted areas (most frequently the basal ganglia and thalamus) displayed increased attenuation, which enhanced further upon infusion of contrast medium. Autopsy of ...
Beier J C - - 1981
Two juvenile robins (Turdus migratorius) died shortly after being captured in Baltimore, Maryland. Both had high erythrocytic parasitemias of mixed Plasmodium infections. Postmortem examination revealed large numbers of exo-erythrocytic malarial schizonts in the liver, spleen, lungs and brain of both cases. Avian malaria was considered the primary cause of death.
Ohlendorf H M - - 1981
Since 1966, 72 herons found dead or moribund in the field have been analyzed for organochlorine chemicals. In addition, 36 herons were obtained through systematic collections, and carcasses were analyzed to determine sublethal exposure to organochlorines. Brains of birds found dead or moribund were analyzed to determine whether the birds ...
Dalens B - - 1981
The authors report a double blind study on 57 full-term neonates prospectively subjected to clinical, electroencephalographical, cerebrospinal fluid and developmental examinations. Usual neonatal pleiocytosis depends on histiomonocytic cells which probably are a reflection of constant small brain damage during delivery. Infants suffering neurological sequelae at age one are recognizable as ...
Nattie E E - - 1981
We studied the response of blood, cerebrospinal fluid (CSF), and brain ionic composition and acid-base status as well as ventilation to acute respiratory acidosis (FICO2 0.08) in lightly anesthetized newborn puppies. Control puppy plasma ions and CSF-plasma ionic distribution ratios were essentially adultlike while in blood a mild, compensated respiratory ...
Lipscomb A P - - 1981
Real-time ultrasound was used to examine the brains of all 95 infants born at less than 33 weeks of gestation who were admitted to the neonatal unit of University College Hospital in 1979. Evidence was obtained which strongly suggested that pneumothorax causes and aggravates haemorrhage into the germinal layer and ...
Melsen B - - 1980
A histological microradiographical analysis was carried out on the cranial base removed at autopsy from three infants--two with microcephalia, one with anencephalia. The histological findings were compared with those from normal individuals of the same age. It was shown that a reduced size of the brain was accompanied by a ...
Mack L A - - 1980
Ultrasound detected cystic intracranial lesions in 18 infants. Lesions included porencephaly (6 infants), hydranencephaly (1 infant), a quadrigeminal cyst (1 infant), Dandy-Walker syndrome (1 infant), and cavum septi pellucidi and Vergae (9 infants). Cystic lesions of the infant brain can be delineated accurately with ultrasound and distinguished from normal ventricular ...
Haruda F - - 1980
Two infants with presumed Candida species brain abscesses are presented. Six other infants with the same problem were found in a search of the literature, and some of the clinical and pathologic features of these patients are presented and discussed. All diagnoses were made post-mortem. There was frequent association with ...
Penn R D - - 1980
Computed tomography scans of normal infants were analyzed by computer methods to determine the average brain tissue density during development. A 20% increase was found from term to 20 weeks of age (29 to 35 Hounsfield units); then no further significant change was found over the next 60 weeks. The ...
Miller R D - - 1980
Mucormycosis in infants is exceedingly rare, and over 90% of reported cases have been fatal. A case of a dehydrated three-week-old infant with involvement of the palate, maxilla, orbit, and brain is described with extensive laboratory and radiological investigation. This infant survived after surgical debridement and therapy with amphotericin B.
Hall R T - - 1980
Cerebrospinal fluid (CSF) lactate dehydrogenase was determined in 19 control infants without asphyxia (Group I), 24 infants with perinatal asphyxia (Group II), and 26 asphyxiated infants with seizures (Group III). Mean birthweights, gestational ages, CSF glucose, protein and red blood cells, and the ages at which the lumbar punctures were ...
Goldberg B D - - 1980
Throughout the ages, man has struggled to define exactly when death takes place. Common law dictated that the presence or absence of a heartbeat indicated whether or not a person was alive. In more recent years, this definition has changed to include brain activity as an important criterion. However, legislation ...
Johnson M L - - 1980
Ultrasound examination of the infant brain has been performed in selected medical centers for many years. However, the equipment necessary for obtaining satisfactory visualization of the brain has only recently become commercially available. Currently, ultrasonography is an excellent, noninvasive, inexpensive, rapid, and safe imaging modality for the evaluation of hydrocephalus ...
Dewbury K C - - 1980
A conventional static ultrasound B scanner with a 6 mm diameter 5 MHz transducer was used to examine the brains of 12 infants between one week and eight months of age using the anterior fontanelle as an ultrasound window. High resolution pictures were obtained allowing assessment of cortical thickness, ventricular ...
Welch K - - 1980
Computed tomographic findings in two infants with Sturge-Weber syndrome include calcification of the brain not visible on plain radiographs. In both cases, the choroid plexus was very prominent, and, in one, a hemangioma of the choroid plexus was found at surgery. In the other, especially dense deposits of mineral were ...
Stancić-Rokotov F - - 1980
A nine-weeks-old infant with haemophilia A developed an intracerebral haematoma. Intracranial operation and removal of the haematoma were performed safely under the cover of highly potent AHF cryoprecipitate. Computerized tomography of the brain is very useful for neurosurgical care of the haemophiliac patients as a noninvasive and atraumatic method of ...
Dłuzniewski A - - 1979
Volumes of nuclei of nervous cells of cortex (C) and caudate nucleus (CN) in brains of fetuses of mothers maintained on methionine--low diet (MLD) or on standard diet (STD) for 2 months before conception and throughout pregnancy were compared acc. to Hintzsche. In both brain areas the class ranges of ...
Madsen J K - - 1979
Examination of neonatal Mongolian gerbil subcommissural organ (SCO) by freeze-fracture electron microscopy reveals that the epithelial layer (the ependyma) possesses distinctive and very complex tight junctions which connect the apical portions of adjacent ependymal cells. The tight junction network of the Mongolian gerbil is more extensive neonatally than in the ...
Pape K E - - 1979
A linear-array real-time ultrasound scanner with a 5 MHz probe was used to examine the brains of 31 infants born at less than 33 weeks of gestation. The equipment was mounted on a small trolley and the infants could easily be scanned in their incubators. 7 of the 31 infants ...
Kaste M - - 1979
Finland was the first country in which brain death was legally accepted. Since 1975, 37 cases of brain death had been recorded in a university hospital in Finland, and these were reviewed. The cause for brain death was intracranial bleeding in 32 cases, other cerebrovascular disorder in two, and intracranial ...
Martínez M - - 1978
Following upon previous studies on the lipid composition of the developing human brain, a further study is presented with the main object of tracing the chemical changes underlying the period of brain 'growth spurt'. Gangliosides and plasmalogens were selected as approximate markers of synaptogenesis and myelination, respectively, and these lipids ...
Blizard D A - - 1978
A single injection of sesame oil on postnatal Day 4 reduced adult bain weight in male and female mice of the C3H/HeJ strain. The same neonatal treatment had no effect on brain weight of heterogeneous mice derived from a cross of 8 inbred strains. In agreement with previous findings in ...
Kero P - - 1978
Heart rate variation (HRV) was measured in 12 children with brain death. Computer analysis demonstrated an overall heart rate variation (RMSM) of 3.5 to 9.6 msec (mean, 6.0 msec). The respective figures for beat-to-beat variation (RMSSD) were 4 to 16 msec (mean, 7.7 msec). Normal infants (RMSM, 20 to 30 ...
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