Search Results
Results 251 - 300 of 1369
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Faro Sebastian S The Woman's Hospital of Texas, Houston, TX 77054, - - 2010
To assess the effect of universal screening and administration of intrapartum antibiotic prophylaxis to prevent early-onset neonatal GBS sepsis at a private tertiary care hospital since issuance of the 2002 CDC guidelines for preventing perinatal GBS disease. Retrospective analysis of women delivering between January 1, 2003 and December 31, 2004 ...
Dutta Sourabh - - 2010
OBJECTIVE: To determine the independent risk factors for early onset neonatal sepsis (EONS) in a setting where the policy is to use intrapartum antibiotic prophylaxis (IAP) for known risk factors. DESIGN: Prospective cohort study. SETTING: Level III neonatal unit in a developing country. PATIENTS: Consecutive mother-infant dyads (gestation < or ...
Onyeama Charles O - - 2009
Escherichia coli as a causative agent for neonatal sepsis is well established. However, there is paucity of reports in the medical literature of E. coli sepsis following scalp electrode placement. We report a preterm infant who developed scalp abscess and E. coli sepsis following a scalp electrode. We recommend a ...
Cohen-Wolkowiez Michael M Department of Pediatrics, Duke University, Durham, NC 27715, - - 2009
Preterm birth is increasing worldwide, and late preterm births, which comprise more than 70% of all preterm births, account for much of the increase. Early and late onset sepsis results in significant mortality in extremely preterm infants, but little is known about sepsis outcomes in late preterm infants. This is ...
Warren S - - 2010
A 29-year-old pregnant woman was admitted to hospital with signs of sepsis and threatened pre-term labour. The premature neonate also showed signs of sepsis. Haemophilus influenzae biotype III was cultured from a midstream urine sample taken from the mother, maternal placental swabs and neonatal blood cultures. The placental and neonatal ...
Tagare A - - 2010
The immature immune system of preterm neonates puts them at higher risk of neonatal sepsis. We conducted a part-blinded randomised controlled trial to compare the effect of routine antibiotic treatment on the incidence of clinical sepsis in preterm neonates. Preterm neonates without other risk factors for infection admitted in the ...
Do Hyun-Jeong - - 2009
A male infant aged 3 months and 1 week had persistently high fever with parotitis that was unresponsive to antibiotics. Mumps was identified by serologic study, but he was finally diagnosed by clinical features as having Kawasaki disease and echocardiographic findings on the 9th day of fever. Parotitis, which is ...
Buddington Randal K - - 2010
BACKGROUND: Postnatal introduction of probiotics results in a low incidence of colonization, whereas maternal fecal and vaginal bacteria colonize the gastrointestinal tract (GIT) of vaginally delivered infants. OBJECTIVE: We tested if probiotic bacteria, fed to three pregnant animal models, would colonize the GIT of offspring delivered vaginally. METHODS: Probiotic strains ...
Cutland Clare L - - 2009
BACKGROUND: About 500,000 sepsis-related deaths per year arise in the first 3 days of life. On the basis of results from non-randomised studies, use of vaginal chlorhexidine wipes during labour has been proposed as an intervention for the prevention of early-onset neonatal sepsis in developing countries. We therefore assessed the ...
Manzoni Paolo P Neonatology and Neonatal Intensive Care Unit, S. Anna Hospital, Azienda Ospedaliera Regina Margherita-S. Anna, C. Spezia 60, 10126 Torino, Italy. - - 2009
Sepsis is a common and severe complication in premature neonates, particularly those with very low birth weight (VLBW) (<1500 g). Whether lactoferrin, a mammalian milk glycoprotein involved in innate immune host defenses, can reduce the incidence of sepsis is unknown. In animal models, the probiotic Lactobacillus rhamnosus GG (LGG) enhances ...
Hossain M Monir - - 2009
Extended-interval dosing of gentamicin has several advantages over conventional multiple-daily dosing for the treatment of sepsis. The study was conducted to evaluate the pharmacokinetics of gentamicin for the treatment of neonatal sepsis in predetermined doses at 24- or 48-hour intervals, according to weight category, and to develop a simplified protocol ...
Yossuck Panitan - - 2009
A three week old extremely low birth weight (ELBW) infant infected by vancomycin-resistant Leuconostoc spp is presented. Treatment with appropriate antibiotics was successful after the percutaneous inserted central catheter (PICC) was removed. The infection with Leuconostoc spp is rare but should be suspected when vancomycin-resistant organisms resembling streptococci are isolated. ...
Zaki Maysaa el-Sayed - - 2009
CONTEXT: Early diagnosis of neonatal sepsis is mandatory. Various markers are used to diagnose the condition. OBJECTIVE: To evaluate the diagnostic value of various clinical data and hematologic parameters, such as total leukocyte count, absolute neutrophil count, immature to total neutrophil ratio, and soluble E-selectin (sE-selectin) in identification and outcome ...
Cancelier Ana Carolina - - 2009
OBJECTIVE: To determine whether levels of interleukin (IL)-6, IL-10, and oxidative parameters in umbilical cord blood could contribute as an indicator of neonatal sepsis in recognized high-risk neonates. DESIGN: Prospective, case-control study. SETTING: Neonatal intensive care unit. SUBJECTS: One hundred twenty consecutive preterm neonates who had at least one other ...
Seale Anna C AC Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute, Kilifi, Kenya. - - 2009
Maternal and child health are high priorities for international development. Through a Review of published work, we show substantial gaps in current knowledge on incidence (cases per live births), aetiology, and risk factors for both maternal and early onset neonatal bacterial sepsis in sub-Saharan Africa. Although existing published data suggest ...
Van Dyke Melissa K - - 2009
BACKGROUND: Group B streptococcal disease is one of the most common infections in the first week after birth. In 2002, national guidelines recommended universal late antenatal screening of pregnant women for colonization with group B streptococcus to identify candidates for intrapartum chemoprophylaxis. METHODS: We evaluated the implementation of the guidelines ...
Onyeama Charles O - - 2009
Escherichia coli as a causative agent for neonatal sepsis is well established. However, there is paucity of reports in the medical literature of E. coli sepsis following scalp electrode placement. We report a preterm infant who developed scalp abscess and E. coli sepsis following a scalp electrode. We recommend a ...
Harvala H - - 2009
BACKGROUND: Human parechoviruses (HPeVs), along with human enteroviruses (HEVs), are associated with neonatal sepsis and meningitis. We determined the relative importance of these viruses and the specific HPeV types involved in the development of central nervous system-associated disease. METHODS: A total of 1575 cerebrospinal fluid (CSF) samples obtained during 2006-2008 ...
Wu Jun-Ho - - 2009
BACKGROUND: Neonatal sepsis is the most serious problem in neonatal intensive care, resulting in significant morbidity and mortality. We evaluated the causative pathogen, drug sensitivity, hematological parameters, clinical course and mortality rate of neonatal sepsis in a Taiwanese medical center and compared our results to those of previous studies conducted ...
Renner L A - - 2009
Two cases of melanotic neuroectodermal tumour of infancy (MNTI), otherwise known as melanotic progonoma, both arising from the maxilla are presented here. The two infants both presented within three months of each other and though clinically Burkitt's lymphoma was stated as a possible diagnosis, the correct diagnosis was made on ...
Destin Kisha G - - 2009
Candida albicans and Candida parapsilosis are important causes of sepsis among premature neonates. The neutrophil is a key element in the control of Candida infections, yet specific neutrophil mechanisms that may contribute to the susceptibility of the premature neonate to candidiasis are not well understood. The hypothesis for this study ...
Vergnano S - - 2010
Group B streptococcus (GBS) is the most common cause of early onset (EO) neonatal infection in the UK. National guidelines for its prevention were introduced in 2003. We assessed the opportunities for prevention amongst cases of EO GBS using the electronic Neonatal Infection Surveillance Network (NeonIN). Culture proven EO GBS ...
Torkaman M - - 2009
INTRODUCTION: Sepsis is a common complication in the neonatal intensive care unit. It is most common in the smallest and most premature infants in whom the clinical presentation can be subtle and nonspecific. The objectives of the present study were to identify the most common organisms causing sepsis and their ...
Gregory Mary Lucia - - 2009
OBJECTIVES: The objectives of this study were to determine the incidence rates of neonatal methicillin-resistant Staphylococcus aureus colonization and infection after the implementation of a NICU methicillin-resistant S aureus surveillance and isolation program and to describe the characteristics of infants with methicillin-resistant S aureus colonization and invasive disease. METHODS: From ...
Kessler Ulf - - 2009
BACKGROUND: Sepsis is a threatening postoperative complication especially in small infants. Regarding the advances in perinatal medicine, its incidence is unknown to date. We aimed to investigate the incidence, risk factors, laboratory findings and outcome of postoperative sepsis in infants younger than 6 months old. METHODS: We examined postoperative sepsis ...
Carlson David - - 2009
OBJECTIVE: The purpose of this preliminary study was to determine normal oropharyngeal flora in healthy, non-CF infants in order to help care givers better interpret culture results obtained from infants with CF. METHODS: Oropharyngeal cultures were obtained from 104 healthy infants <12 months old. Cultures were obtained using the same ...
Doerr Beth B Educational Concerns for Hunger Organization, North Ft. Myers, Florida, - - 2009
Leaves of the tropical tree Moringa oleifera are widely promoted in areas of chronic malnutrition as nutritional supplements for weaning infants and nursing mothers. Adoption, in these circumstances may hinge upon taste, which can vary greatly amongst cultivars. It is widely assumed that this taste variation is primarily germplasm-dependent, and ...
Tanaka Shigemitsu - - 2009
The influence of antibiotic exposure in the early postnatal period on the development of intestinal microbiota was monitored in 26 infants including five antibiotic-treated (AT) subjects orally administered a broad-spectrum antibiotic for the first 4 days of life and three caesarean-delivered (CD) subjects whose mothers were intravenously injected by the ...
Shin Youn-Jeong - - 2009
Neonatal sepsis is a severe clinical syndrome characterized by systemic signs of infection, shock and system organ failure; diagnosis is confirmed on positive culture from a normally sterile site(s). There are few reports comparing incidence, mortality, and risk factors between clinically diagnosed sepsis and that confirmed by culture. All infants ...
Sundaram Venkataseshan V Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, - - 2009
To investigate the relationship between score for neonatal acute physiology II (SNAP II) applied within 12 hours from the onset of severe sepsis, and death and persistent organ dysfunction (OD). Prospective cohort study. Level III neonatal intensive care unit. Neonates with severe sepsis. SNAP II was applied within the first ...
Cohen-Wolkowiez Michael M Department of Pediatrics, Duke University, Durham, NC 27715, - - 2009
Systemic infections in premature and term infants cause significant morbidity and mortality in spite of appropriate antimicrobial therapy. Consequently, immunotherapy has emerged as a potential adjuvant therapeutic modality to reduce the incidence and mortality associated with neonatal sepsis. The most recent findings during the review period include systematic reviews of ...
Gries Delores M - - 2009
Healthy infants frequently acquire Staphylococcus aureus colonization; however, the modes of transmission are not well defined. In this study, 8 of 23 (35%) infants cultured at age 2 weeks acquired S aureus carriage, but only 1 infant had a family member with nasal carriage of the same clone, suggesting that ...
Maayan-Metzger Ayala - - 2009
BACKGROUND: Early-onset neonatal sepsis is a major cause of morbidity and mortality among newborn infants. OBJECTIVES: To determine the incidence, type of pathogens and resistance to antibiotics among newborns with early-onset neonatal sepsis, and to identify the risk factors predisposing infants to resistant pathogens in order to reevaluate antibiotic regimens ...
Kristóf Katalin - - 2009
Prematurity has got special challenge for clinicians and also other medical staff, such as microbiologists. Immature host defense mechanisms support early-onset sepsis, which can be very serious with very high mortality. While the past decade has been marked by a significant decline in early-onset group B streptococcal (GBS) sepsis in ...
Chen Hsiao-Neng - - 2009
OBJECTIVE: The objective of this study was to review the early clinical profiles and outcomes of very-low-birth-weight (VLBW) neonates with late-onset sepsis caused by Enterobacter cloacae. METHODS: We reviewed the medical records of VLBW neonates whose blood and/or cerebral spinal fluid yielded E. cloacae after 3 days of hospitalization in ...
Adlerberth I - - 2009
In adult individuals, the intestinal microbiota comprises several hundred, mostly anaerobic, bacterial species. This complex ecosystem is formed through the successive establishment of different bacteria in infancy and early childhood. Facultative and aerotolerant bacteria establish first, followed by more and more strict anaerobes. The bacteria derive from different sources and ...
Carr Robert - - 2009
BACKGROUND: Systemic sepsis is a major cause of death in preterm neonates. There are compelling theoretical reasons why treatment with haemopoietic colony-stimulating factors might reduce sepsis and improve outcomes, and as a consequence these agents have entered into use in neonatal medicine without adequate evidence. We assessed whether granulocyte-macrophage colony ...
Zuckerbraun Noel S - - 2009
OBJECTIVE: To describe the occurrence of serious bacterial infections (SBIs) in well-appearing, afebrile infants aged 60 days or younger with an apparent life-threatening event (ALTE). STUDY DESIGN: We retrospectively reviewed microbiologic testing in a cohort of well-appearing, afebrile infants aged 60 days or younger who presented with an ALTE to ...
Zaidi Anita K M - - 2009
INTRODUCTION: Knowledge of pathogens causing infections in young infants (up to 90 days of life) is essential for devising community-based management strategies. Most etiological data from developing countries are hospital-based and may have little relevance to communities in which most babies are born at home. METHODS: We searched the literature ...
Bentz A I - - 2009
BACKGROUND: Coagulopathy is a potentially underrecognized complication of sepsis and septic shock in critically ill neonatal foals. HYPOTHESIS: Critically ill neonatal foals have abnormalities in coagulation that are associated with disease severity and outcome. ANIMALS: Foals <72 hours old admitted to a neonatal intensive care unit. METHODS: Prospective, observational study. ...
Spada Serena - - 2009
Procalcitonin (PCT) has been proposed as an interesting marker in the diagnosis, prognosis, and response to treatment of patient with neonatal sepsis. Fifty-nine neonates (34 males and 25 females) with a mean gestational age of approximately 31 weeks and a mean weight of about 1750 g admitted in the Neonatal ...
Pettas Nikolaos S - - 2009
Primary sternal osteomyelitis is extremely rare in children and only very few cases have been reported in the international literature. A 40 days old Caucasian infant was referred to our clinic with a 4 days history of fever and malaise, accompanying a painful swelling of four days duration involving the ...
Waliullah M S - - 2009
This prospective study was undertaken in Dhaka Shishu hospital, Bangladesh from 15th Oct. 2005 to 15th October 2006 to determine the Risk factors, Clinical manifestation and bacteriological profile of neonatal sepsis. Eighty suspected cases of septicaemia admitted in neonatal ward of Dhaka Shishu Hospital were included in this study. Patients, ...
Mohanty Srujana - - 2009
Sepsis due to Salmonella enterica serovar Typhi and Paratyphi A is rare in neonates. Though described as a mild and unrecognized illness in infants, life-threatening complications and even deaths have been reported. We present five cases of neonatal septicaemia due to S. Typhi and S. Paratyphi A. The cases were ...
Darmstadt Gary L - - 2009
BACKGROUND: A number of special issues must be considered when selecting simple, safe, inexpensive, and effective antimicrobial regimens for treatment of neonatal sepsis in developing country community settings. METHODS: We reviewed available data regarding pharmacologic profiles of parenteral antibiotics with specific attention to properties relevant to their use in the ...
Beuchée Alain - - 2009
BACKGROUND: Late-onset sepsis in the premature infant is frequently revealed by severe, unusual and recurrent bradycardias. In view of the high morbidity and mortality associated with infection, reliable markers are needed. OBJECTIVES: It was the aim of this study to determine if heart rate (HR) behavior may help the diagnosis ...
Elbaradie Sahar M Y - - 2009
OBJECTIVE: To detect the magnitude of group B streptococcal (GBS) colonization and disease among a sample of pregnant women and their infants in Egypt. STUDY DESIGN: Prospective observational study. PARTICIPANTS: The study included 95 pregnant females, 35-37 weeks of gestational age, attending the antenatal outpatient clinic at AlFayom University Hospital ...
Chirico Gaetano - - 2009
Because of the high susceptibility to infections, antibiotics are the most widely used drugs in newborns. The result of antibiotic use, however, may be strongly influenced by the peculiar physiology of the neonate, characterized by the delicate process of adaptation from intra- to extra-uterine life. Additional important factors that may ...
Pereira Sylvia Maria Porto - - 2009
The aim of this study is to identify risk factors for sepsis-related mortality in low birth weight (<1500 g) infants. We performed retrospective cohort study to investigate risk factors for sepsis-related mortality in all neonates birth weight <1500 g admitted to Level III neonatal intensive care unit, Brazil, April 2001/September ...
Makhoul Imad R - - 2009
BACKGROUND: According to the U.S. Centers for Disease Control guidelines, prolonged rupture of membranes mandates intrapartum antimicrobial prophylaxis for group B Streptococcus whenever maternal GBS status is unknown. OBJECTIVES: To evaluate the local incidence, early detection and outcome of early-onset GBS sepsis in neonates born at 35-42 weeks gestation after ...
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