Search Results
Results 151 - 200 of 1370
1 2 3 4 5 6 7 8 9 10 >
Askie Lisa M LM NHMRC Clinical Trials Centre, University of Sydney, (Parramatta Road), Camperdown, (2050), Australia. - - 2011
The appropriate level of oxygenation for extremely preterm neonates (<28 weeks' gestation) to maximise the greatest chance of survival, without incurring significant morbidity, remains unknown. Infants exposed to lower levels of oxygen (targeting oxygen saturations of <90%) in the first weeks of life are at increased risk of death, cerebral ...
Matthews Emma E Institute of Neurology and Medical Research Council Centre for Neuromuscular Disease, National Hospital for Neurology and Neurosurgery, University College London, London, - - 2011
To describe stridor as the presenting feature in a neonate with the skeletal muscle sodium channelopathy paramyotonia congenita. Case report. Outpatient neuromuscular clinics at Great Ormond Street Hospital for Children and the Medical Research Council Centre for Neuromuscular Disease at the National Hospital for Neurology and Neurosurgery, London, England. A ...
Bessell Alyson A Department of Oral and Dental Sciences, University of Bristol, Lower Maudlin Street, Bristol, UK, BS1 - - 2011
Cleft lip and cleft palate are common birth defects, affecting about one baby of every 700 born. Feeding these babies is an immediate concern and there is evidence of delay in growth of children with a cleft as compared to those without clefting. In an effort to combat reduced weight ...
Conde-Agudelo Agustin A Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development/National Institutes of Health/Department of Health and Human Services, Detroit, Michigan, - - 2011
Kangaroo mother care (KMC), originally defined as skin-to-skin contact between a mother and her newborn, frequent and exclusive or nearly exclusive breastfeeding, and early discharge from hospital, has been proposed as an alternative to conventional neonatal care for low birthweight (LBW) infants. To determine whether there is evidence to support ...
Alfaleh Khalid K Department of Pediatrics (Division of Neonatology), King Saud University, King Khalid University Hospital and College of Medicine, Department of Pediatrics (39), P.O. Box 2925, Riyadh, Saudi Arabia, - - 2011
Necrotizing enterocolitis (NEC) and nosocomial sepsis are associated with increased morbidity and mortality in preterm infants. Through prevention of bacterial migration across the mucosa, competitive exclusion of pathogenic bacteria, and enhancing the immune responses of the host, prophylactic enteral probiotics (live microbial supplements) may play a role in reducing NEC ...
Varg Ivan I Institute of Histology and Embryology, Faculty of Medicine, Comenius University in Bratislava, Slovakia. - - 2011
The thymus is a central lymphatic organ reaching its largest size after the delivery. Its size is significantly affected by endogenous and exogenous negative factors. In our research, we investigated the relationship between the size of the thymus determined by sonography and anthropometric parameters as well as indexes demonstrating the ...
Hemels Marieke A C MA Department of Neonatology, Wilhelmina Children's Hospital, Utrecht, The Netherlands. - - 2011
The typical empiric therapy for coagulase-negative staphylococcal (CONS) sepsis includes vancomycin. In our neonatal intensive care unit, we have consistently avoided the use of vancomycin to treat CONS sepsis, except for specific cases, and have used instead cefazolin as empiric agent. The clinical outcome of infants with CONS sepsis was ...
Elder Dawn E - - 2010
PURPOSE: This study aimed to determine the characteristics of respiratory events in preterm infants with clinically concerning apnoea at or beyond 35 weeks postmenstrual age and to compare these findings with a group of preterm infants ready for discharge, without clinically concerning apnoea. METHODS: Infants born at <32 weeks of gestation and ...
Eichenwald Eric C - - 2011
Apnea of prematurity is one of the most common diagnoses in the NICU. Because resolution of apnea is a usual precondition for discharge from the hospital, different monitoring practices might affect length of stay for premature infants. Our objective was to compare the proportion of 33 to 34 weeks' gestational ...
Cheng Alan T L - - 2011
Background:  We present six cases of infants with Robin sequence and severe obstructive sleep apnoea who failed treatment with nasal mask continuous positive airway pressure (CPAP). Surgical intervention with mandibular distraction osteoneogenesis with glossopexy meant tracheostomy was avoided. Polysomnography (PSG) was used to document the severity of the obstructive sleep ...
Labad Javier - - 2010
INTRODUCTION: Some postpartum women experience intrusive thoughts of harming the infant. The hypothalamic-pituitary-adrenal (HPA) axis, which has been linked to postpartum depression, may play a role in the aetiology of postpartum thoughts of harming the infant. We aimed to study whether HPA axis hormones measured early postpartum are related to ...
Greenberg R G RG Department of Pediatrics, Duke University, Durham, NC, - - 2011
The purpose of this study is to examine the results of repeat lumbar puncture in infants with initial positive cerebrospinal fluid (CSF) cultures in order to determine the clinical characteristics and outcomes of infants with repeat positive cultures. Cohort study of infants with an initial positive CSF culture undergoing repeat ...
Vance Gregory A - - 2010
Background/Aims: Hypoxic-ischemic encephalopathy (HIE) refers to neonatal neurological signs and symptoms of hypoxia and/or ischemia. Our aim was to determine the accuracy of ICD-9 codes to identify newborns with HIE confirmed by umbilical cord blood analysis. Methods: ICD-9 codes in the newborn chart for birth trauma, birth asphyxia, intrauterine hypoxia, ...
Sado Toshiyuki T Department of Obstetrics and Gynecology, Nara Medical University, Nara, - - 2011
Up to 10% of pregnant women have preterm birth that might be refractory to current therapy. Infections and asphyxia related to preterm birth are the causes of death in the majority of neonates and therefore represent an urgent clinical need. The present article reviews the English language literature for preclinical ...
Ambalavanan Namasivayam - - 2011
To determine (1) the magnitude of clustering of bronchopulmonary dysplasia (36 weeks) or death (the outcome) across centers of the Eunice Kennedy Shriver National Institute of Child and Human Development National Research Network, (2) the infant-level variables associated with the outcome and estimate their clustering, and (3) the center-specific practices ...
Cogo Paola E - - 2010
RATIONALE: Limited data are available on predictors for surfactant retreatment in preterm infants with respiratory distress syndrome (RDS). OBJECTIVE: To study the pharmacokinetics of exogenous surfactant and the clinical parameters associated with surfactant redosing. METHODS: Exogenous surfactant pharmacokinetics was studied in 125 preterm infants (birth weight 997 ± 432 g; gestational age 28.0 ± 2.6 weeks) ...
Pappas Athina A Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI 48201, USA. - - 2011
To evaluate the association between early hypocarbia and 18- to 22-month outcome among neonates with hypoxic-ischemic encephalopathy. Data from the National Institute of Child Health and Human Development Neonatal Research Network randomized, controlled trial of whole-body hypothermia for neonatal hypoxic-ischemic encephalopathy were used for this secondary observational study. Infants (n ...
Saugstad Ola Didrik - - 2010
Background: The optimal arterial oxygen saturation in the first weeks of life is unknown for immature newborn infants. Objectives: To determine the effect of targeting high versus low oxygen saturation in the first weeks of life on the outcome of very low and extremely low birth weight infants. Methods: Randomized ...
Henderson J - - 2010
Background  It is well recognized that breast milk is the best form of nutrition for babies. However, many women do not breastfeed or give up soon after birth. Some report feeling unsupported in the post-natal period and many stop breastfeeding earlier than they would have wished. This study aimed to ...
Koike Yasunori - - 2011
Cow's milk allergy (CMA) in the neonatal period is thought to include several clinical conditions, yet the pathophysiology remains unclear. We report here the case of a term newborn infant who showed hematochezia 36 hours after the first feeding with cow's milk formula. His serum immunoglobulin E levels were not ...
Dreyer ZoAnn E ZE Texas Children's Hospital, Houston, TX, USA. - - 2011
Although the majority of children with acute lymphoblastic leukemia (ALL) are cured with current therapy, the event-free survival (EFS) of infants with ALL, particularly those with mixed lineage leukemia (MLL) gene rearrangements, is only 30% to 40%. Relapse has been the major source of treatment failure for these patients. The ...
Balaguer Albert - - 2011
Background: There is a need for a better etiologic classification of preterm births and for tools to help to determine the possible etiologies of these births. Objective: Having previously developed the Barcelona Etiology of Prematurity (BEP) algorithm, based on a new classification for preterm births, we sought to validate this ...
Cho Anthony - - 2010
Consider treatment when the infant is having difficulty breastfeeding. Infants with mild to moderate tongue-tie, or ankyloglossia, are likely to breastfeed successfully and usually require no treatment (strength of recommendation [SOR]: B, a prospective controlled trial and a case-control study). However, mothers of infants with any degree of tongue-tie who ...
Mather Emily - - 2010
The impact of novel labels on visual processing was investigated across two experiments with infants aged between 9 and 21 months. Infants viewed pairs of images across a series of preferential looking trials. On each trial, one image was novel, and the other image had previously been viewed by the ...
Bornstein Marc H - - 2011
Five-month-old infants of nondepressed and clinically depressed mothers were habituated to either a face with a neutral expression or the same face with a smile. Infants of nondepressed mothers subsequently discriminated between neutral and smiling facial expressions, whereas infants of clinically depressed mothers failed to make the same discrimination.
Nelson Eliza L - - 2010
In human and chimpanzee infants, neonatal rightward supine head orientation bias predicts later right hand use preference. In an evolutionarily older primate species such as the rhesus monkey, a left hand preference has been reported, but there are no data on head orientation biases. Supine head orientation bias was measured ...
Hassan Hazem E HE Pharmacokinetics and Biopharmaceutics Laboratory, Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland, - - 2011
Ureaplasma spp. respiratory tract colonization is a significant risk factor for bronchopulmonary dysplasia (BPD), a chronic lung disorder in preterm infants. As an initial step preparatory to future clinical trials to evaluate the clinical efficacy of azithromycin to prevent BPD, the authors characterized the pharmacokinetics, safety, and biological effects of ...
Nelson Eliza L EL Department of Psychology, University of Massachusetts, Amherst, Massachusetts, USA. - - 2011
In human and chimpanzee infants, neonatal rightward supine head orientation bias predicts later right hand use preference. In an evolutionarily older primate species such as the rhesus monkey, a left hand preference has been reported, but there are no data on head orientation biases. Supine head orientation bias was measured ...
Thakur Neil H - - 2010
BACKGROUND: Isolated borderline low conus medullaris is a frequent finding on screening lumbar sonography of unknown significance that often prompts further imaging and clinical follow-up. OBJECTIVE: To determine the clinical outcome and utility of follow-up neuroimaging in infants with isolated borderline low conus on lumbar sonography. MATERIALS AND METHODS: We ...
Peker Erdal - - 2011
In this study, we studied global fibrinolytic capacity (GFC) in newborn infants with sepsis. Sixty-one newborn infants, admitted to neonatal intensive care unit at Yuzuncu Yil University Hospital were enrolled in this study. White blood cell count, immature (I) / mature (M) neutrophil ratios, prothrombin time, and d-dimer levels were ...
Stets Manuela - - 2011
Event-related Potentials (ERP) studies are a widely used methodology to investigate the early cognitive development in infants of all age ranges. We examined changes in amplitude contribution in a set of previously published data (see [4]) in relation to the Negative component as a function of number of trials contributing ...
Cosar Hese - - 2010
Reticular dysgenesis (RD) is a rare congenital immunodeficiency classified within the severe combined immunodeficiencies (SCIDs) and characterized by impairment of both lymphoid and myeloid cell development. Neutropenia unresponsive to recombinant human granulocyte colony-stimulating factor (rGCSF) is the hallmark of RD and the clinical course is rapidly fatal due to overwhelming ...
Zenciroglu Aysegul - - 2010
Purpura fulminans is an acute and frequently fatal disorder characterized by sudden onset of progressive cutaneous hemorrhage and necrosis due to dermal vascular thrombosis and disseminated intravascular coagulation. The authors present a neonate with extensive purpura fulminans due to group B streptoccoccal septicemia and evaluated the attributable clinical mortality and ...
Bradford Rebecca - - 2011
Coagulase-negative staphylococci (CoNS) are the most common cause of biofilm-associated sepsis in very low birth weight infants (VLBW). Standard biofilm assays may not predict the pathogenic potential of CoNS since biofilm production is regulated by diverse environmental stimuli. Staphylococcus epidermidis isolated from blood cultures from VLBW infants were evaluated for ...
Ogunlesi Tinuade A - - 2011
Aim:  Sepsis is a major contributor to newborn deaths in the developing world. The objective is to determine the prevalence of newborn sepsis, the bacterial pathogens and antibiotic sensitivity pattern of the isolates. Method:  A study of consecutive babies hospitalised in Sagamu, Nigeria, with risk factors for or clinical features ...
Bas Ahmet Yagmur - - 2011
Methylergonovine (MEV) is a semi-synthetic ergot alkaloid used in the prevention and control of postpartum hemorrhage. This report describes 12 newborns born on the same day in a local country hospital in Turkey and developed sepsis-like symptoms and encephalopathy within the first 6 h of life due to accidental administration of ...
Zicari A M - - 2010
The authors report a rare case of partial diaphragmatic eventration in a 4-month-old infant with recurrent wheezing and low serum IgA values. Because of persistent respiratory symptoms after therapy with inhaled short-acting beta2 agonists and inhaled nebulized corticosteroids, surgery was undertaken to correct the defect. Despite surgery, the clinical symptoms ...
Wu Chang-Teng - - 2010
We report the case of a previously healthy 8-month-old infant girl with Pseudomonas aeruginosa sepsis who presented to a pediatric emergency department with multiple ecthyma gangrenosum. Skin manifestations are uncommon in Pseudomonas infection. Ecthyma gangrenosum is a rare, distinct skin disorder associated with potentially fatal underlying Pseudomonas sepsis. Although typically ...
Talbert Alison W A - - 2010
Bacterial sepsis is thought to be a major cause of young infant deaths in low-income countries, but there are few precise estimates of its burden or causes. We studied invasive bacterial infections (IBIs) in young infants, born at home or in first-level health units ("outborn") who were admitted to a ...
Abu-Maziad Asmaa A Department of Pediatrics, University of Iowa, Children's Hospital, Iowa City, Iowa 52242, - - 2010
This study is a retrospective, case control study involving 535 preterm infants examining the roles of sequence polymorphisms in genes that mediate host immune responses to bacterial infection in newborn infants. A total of 49 single nucleotide polymorphisms (SNPs) in 19 candidate genes including inflammatory cytokines (IL6, IL10, IL1B, and ...
Benjamin Daniel K DK Jr Department of Pediatrics, Duke University, Duke Clinical Research Institute, 2400 Pratt St, Durham, NC 27705, USA. - - 2010
Invasive candidiasis is a leading cause of infection-related morbidity and mortality in extremely low birth weight (<1000-g) infants. We quantified risk factors that predict infection in premature infants at high risk and compared clinical judgment with a prediction model of invasive candidiasis. The study involved a prospective observational cohort of ...
Berardi Alberto - - 2011
Objective. Current guidelines for prevention of group B streptococcus (GBS) early-onset infection recommend to administer antibiotic during labor at least 4 h prior to delivery (adequate prophylaxis). We aimed to determine if neonatal GBS colonization may be significantly decreased in case of inadequate (<4 h) duration of ampicillin prophylaxis. Methods. In prospective, cohort study, ...
Erbay Ay┼če - - 2010
Despite the relatively recent introduction of propranolol in the treatment of infantile hemangiomas, there can be little doubt of its efficacy. With regard to safety issues, there are no prior data for very low weight infants. In this study, we used propranolol in preterm and very low weight infants. We ...
Byard Roger W - - 2010
Birth under water has become a widely disseminated technique that is promoted to improve the quality of labor. The case of a 42-week gestation male infant is reported who died of respiratory and multiorgan failure secondary to florid pneumonia and sepsis due Pseudomonas aeruginosa following a water birth. Other infants ...
Posteraro Brunella - - 2010
Candida colonization is an important predictor for development of invasive fungal infection (IFI). We investigated whether early detection of Candida mannan (Mn) in bronchoalveolar lavage fluid (BALF) reduces IFI among preterm infants. We conducted an observational study of infants with gestational age of < or =28 weeks, where a group ...
Ozdemir Ozgur - - 2010
In this study, we aimed to evaluate cord blood mannose binding levels (MBL), to evaluate possible relationship between cord blood MBL levels with neonatal sepsis and culture confirmed neonatal sepsis in preterm newborn with gestational age below 34 weeks with fetal inflammatory response syndrome (FIRS). Forty-four randomly selected < or ...
Gouyon Jean-Bernard - - 2010
The persistence of a patent ductus arteriosus (PDA) in preterm infants complicates their clinical course and may contribute to increased morbidity. Intravenous preparations of ibuprofen constitute one of the standard therapies for closure of a PDA. However, the unavailability of intravenous ibuprofen in certain regions of the world and the ...
Kuhn Pierre - - 2010
In 2001 France issued a new set of guidelines for the use of antenatal antibiotics (AA). These guidelines recommended intrapartum antimicrobial prophylaxis (IAP) to prevent group B streptococcal (GBS) disease and AA to prolong pregnancy in the event of preterm premature rupture of membranes (AA for PPROM). This study aims ...
Fairchild Karen D - - 2010
Early detection of late-onset neonatal sepsis, before the onset of obvious and potentially catastrophic clinical signs, is an important goal in neonatal medicine. Sepsis causes a well-known series of physiologic changes including abnormalities of blood pressure, respiration, temperature, and heart rate, and less well-known changes in heart rate variability. Although ...
Smith Ann A Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY, - - 2010
Gram-negative bacilli (GNB) cause as many as 20% of episodes of late-onset sepsis among very low birth weight (VLBW, birth weight < or =1500 g) infants in the neonatal intensive care unit. As the gastrointestinal (GI) tract can serve as a reservoir for GNB, we hypothesized that VLBW infants with ...
1 2 3 4 5 6 7 8 9 10 >