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Ekwochi U - - 2014
Background: Being the highest contributor to under-5 mortality, neonatal mortality and morbidity has great impact to the attainment of millennium development goals 4 (MDG 4). In Nigeria and other developing countries, this indicator strongly poses a major challenge in achieving this goal. Objectives: To determine the morbidity and mortality pattern ...
Karkee Rajendra R School of Public Health and Community Medicine, BP Koirala Institute of Health Sciences, Dharan, - - 2014
Many deliveries in low income countries still take place at home and the newborns are often not weighed. This community-based study ascertained the incidence of low birthweight (LBW) and compared the birthweight between home- and facility-born neonates in central Nepal. A total of 701 pregnant women from the Kaski district ...
Washburn Lisa K LK 1Department of Pediatrics, Wake Forest School of Medicine, - - 2014
Hypothesis/introduction:Preeclampsia is associated with alterations in the maternal renin-angiotensin-aldosterone system (RAAS), increased blood pressure (BP), and cardiovascular risk in the offspring. We hypothesized that preeclampsia is associated with alterations in the RAAS in the offspring that persist into adolescence. We compared components of the circulating (n = 111) and renal ...
Brunner S S Else Kröner-Fresenius-Center for Nutritional Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, - - 2014
Adipokines in breast milk have been associated with infant growth trajectories. We aimed to explore the relationship of leptin and adiponectin in breast milk with infant weight gain and body composition up to the age of 2 years. Breast milk samples were collected from exclusively or partially breastfeeding mothers at ...
Maheshwari Akhil A 1] Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA [2] Department of Pediatrics, University of Illinois at Chicago, Chicago, IL, - - 2014
Background:The goal was to identify cytokines associated with necrotizing enterocolitis (NEC). Based on our earlier reports of decreased tissue expression of transforming growth factor (TGF)-β, we hypothesized that infants with NEC also have low blood TGF-β levels. We further hypothesized that because fetal inflammation increases the risk of NEC, infants ...
Vandenplas Yvan Y Department of Pediatrics, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium, - - 2014
Guidelines recommend the use of extensively hydrolyzed cow's milk protein-based formulas (eHF) in the treatment of infants with cow's milk protein allergy (CMPA). Extensively hydrolyzed rice protein infant formula (eRHF) has recently become available and could offer a valid alternative. A prospective trial was performed to evaluate the hypo-allergenicity and ...
Bishnoi Ram N RN Division of Pediatric Cardiology, Johns Hopkins University School of Medicine, 1800 Orleans street M2328, Baltimore, MD, 21287, USA, - - 2014
This study aimed to assess the technical aspects of atrial septal defect (ASD) closure using the Amplatzer septal occluder (ASO) and the Gore Helex septal occluder (GHSO) for infants weighing less than 8 kg and to determine the safety, effectiveness, and near-to-intermediate-term outcome of the closure. The Mid-Atlantic Group of Interventional ...
Johnson L L 1] Centre for Exercise, Nutrition and Health Sciences, School of Policy Studies, University of Bristol, Bristol, UK [2] Health Behaviour Research Centre, Department of Epidemiology and Public Health, University College London, London, - - 2014
Objective:Infant growth trajectories, in terms of size, tempo and velocity, may program lifelong obesity risk. Timing of breastfeeding cessation and weaning are both implicated in rapid infant growth; we examined the association of both simultaneously with a range of growth parameters.Design:Longitudinal population-based twin birth cohortSubjects:The Gemini cohort provided data on ...
Studer Jacqueline J Institute of Legal Medicine, University of Zurich, Winterthurerstrasse 190/52, 8057 Zurich, - - 2014
BACKGROUND:Failures in the regulation of the homeostatic water balance in the brain are associated with severe cerebral edema and increased brain weights and may also play an important role in the pathogenesis of sudden infant death syndrome (SIDS). We genotyped three single nucleotide polymorphisms (SNPs) in the aquaporin-4 water channel ...
Sania Ayesha A Department of Global Health and Population, Harvard School of Public Health, Boston, Massachusetts, - - 2014
Objectives were to examine the growth patterns of preterm and growth-restricted infants and to evaluate the associations of prematurity and intrauterine growth restriction (IUGR) with risk of stunting, wasting and underweight. Data from a cohort of HIV-negative pregnant women-infant pairs were collected prospectively in Tanzania. Small for gestational age [SGA, ...
Alkan Senem S Department of Neonatology, Tepecik Training and Research Hospital , Yenisehir, Izmir , - - 2014
Abstract Background: It is suggested that there may be expanded use of surfactant replacement for the neonatal diseases such as meconium aspiration syndrome (MAS), pneumonia and possibly bronchopulmonary dysplasia (BPD). Objective: To evaluate the characteristics and short-term outcome of the neonates given exogenous surfactant because of the diseases other than ...
Siles Pascale P Department of Radiology, La Timone Children's Hospital, 264 rue Saint Pierre, 13005, Marseille, France, - - 2014
Magnetic resonance cholangiopancreatography (MRCP) could aid in the diagnosis of biliary atresia, a hepatic pathology with thin, irregular or interrupted biliary ducts. There is little published evidence of MRCP appearances in normal neonates and young infants. To assess the use of MR cholangiopancreatography in visualizing the biliary tree in neonates ...
Gishti Olta O The Generation R Study Group (Gishti, Gaillard, Heppe, Durmus, Jaddoe), Department of Pediatrics (Gishti, Gaillard, Heppe, Duijts, Jaddoe), Department of Epidemiology, (Gishti, Gaillard, Heppe, Hofman, Jaddoe), Department of Obstetrics and Gynecology (Steegers), Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Radiology (Manniesing), Radboud University Nijmegen, Nijmegen, The Netherlands, Nutricia Research, Utrecht, The Netherlands (Abrahamse, Van der - - 2014
Context: Higher infant growth rates are associated with an increased risk of obesity in later life. Objective: We examined the associations of longitudinally measured fetal and infant growth patterns with total and abdominal fat distribution in childhood. Design, Settings and participants: We performed a population-based prospective cohort study among 6,464 ...
Tibu Florin F University of - - 2014
Associations between low birth weight and prenatal anxiety and later psychopathology may arise from programming effects likely to be adaptive under some, but not other, environmental exposures and modified by sex differences. If physiological reactivity, which also confers vulnerability or resilience in an environment-dependent manner, is associated with birth weight ...
Meehan Sean S Division of Epidemiology & Public Health, School of Medicine, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham, - - 2014
Despite numerous studies reporting an elevated risk of infant mortality among women who are obese, the magnitude of the association is unclear. A systematic review and meta-analysis was undertaken to assess the association between maternal overweight or obesity and infant mortality. Four health care databases and gray literature sources were ...
Cernada María M Health Research Institute (Instituto de Investigación Sanitaria) La Fe, Valencia, - - 2014
Bacterial sepsis is associated with high morbidity and mortality in preterm infants. However, diagnosis of sepsis and identification of the causative agent remains challenging. Our aim was to determine genome-wide expression profiles of very low birth weight (VLBW) infants with and without bacterial sepsis and assess differences. This was a ...
Motta Mario M From the Neonatology and Neonatal Intensive Care Unit, Children's Hospital of Brescia , Brescia , - - 2014
Objective: To assess the diagnostic and prognostic utility of CD64 expression as a marker of early-onset sepsis (EOS) in very low birth weight (VLBW) neonates. Methods: Neutrophil CD64 expression (CD64 index) was assessed in 129 VLBW neonates within 72 h after birth. The accuracy of the CD64 index in predicting ...
Fustiñana Carlos A CA Servicio de Neonatología, Hospital Italiano de Buenos - - 2014
Introduction. The WHO standards have been used as a gold standard for growth assessment in preterm infants since 1986. The introduction of the WHO standards in Argentina could improve detection of sub-optimal growth. Objective. To compare the proportion of growth retardation in terms of weight, body height and head circumference ...
Bancalari M Aldo A Unidad de Neonatologia, Servicio de Pediatría, Hospital Guillermo Grant - - 2014
Ophthalmological outcomes in a series ofchildrenwithretinopathy ofprematurity (ROP) in the threshold stage treated withintravitreal bevacizumab are reported. Twelve very low birth weight (VLBW) preterm infants who were administered intravitreal bevacizumab as monotherapy for retinopathy of prematurity in the threshold stage and in whom standard laser photocoagulationtherapy was contraindicatedwere evaluated. Ophthalmological ...
Ericson Jessica E JE aDuke Clinical Research Institute bDepartment of Pediatrics, Duke University, Durham, North Carolina, - - 2014
Invasive candidiasis is a serious infection in hospitalized infants that results in significant mortality and morbidity. Fluconazole is approved by the US Food and Drug Administration for prophylaxis of invasive candidiasis in patients undergoing bone marrow transplantation but is not approved for use in infants. This review will describe the ...
Parker Ruslana R Neonatal Nurse Practitioner Program, University of Utah, and Evidence Based Practice Briefs, University of Utah, Salt Lake - - 2014
Necrotizing enterocolitis (NEC) is a gastrointestinal emergency that leads to inflammation and intestinal necrosis. Although probiotics can decrease the incidence of NEC, consistent recommendations for probiotic administration to very low-birth-weight (VLBW) neonates are lacking. Here, the best available evidence is reviewed and a practice guideline for probiotic administrations to VLBW ...
Mines Daniel D HealthCore, Inc., Wilmington, DE, - - 2014
First marketed in the USA in 1996, topiramate (TPM) is an antiepileptic drug later approved for migraine prophylaxis, and in 2012 for weight loss in combination with phentermine. Some studies indicate an elevated prevalence of oral cleft (OC) in infants exposed to TPM in utero. We evaluated the association between ...
Lurbe Empar E Department of Pediatrics, Consorcio Hospital General and Hypertension Clinic, Hospital Clinico, INCLIVA, University of Valencia, Valencia, Spain; and Centros de Investigación Biomédica en Red Fisiopatología Obesidad y Nutrición (CB06/03), Instituto de Salud Carlos III, Madrid, - - 2014
The present prospective study assessed the impact of birth weight (BW) and postnatal weight gain on blood pressure and metabolic profile during the first 5 years of life. One hundred thirty-nine newborns (63 women) born at term after uncomplicated pregnancies and in the absence of perinatal illness were included. Subjects ...
Mohamed Sarar - - 2014
Congenital toxoplasmosis has a wide range of presentation at birth varying from severe neurological features such as hydrocephalus and chorioretinitis to a well appearing baby, who may develop complications late in infancy. While neuroendocrine abnormalities associated with congenital toxoplasmosis are uncommon, isolated central diabetes insipidus is extremely rare. Here, we ...
Thomson Jessica L JL United States Department of Agriculture, Agricultural Research Service, 141 Experiment Station Road, Stoneville, MS 38776, United States. Electronic address: - - 2014
Excessive and inadequate gestational weight gain can complicate a woman's pregnancy and put her and her child at risk for poor delivery and birth outcomes. Further, feeding and activity habits established early in life can significantly impact the development of childhood obesity. The on-going Delta Healthy Sprouts Project is a ...
Bodnar Lisa M LM Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA; Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of Pittsburgh, Pittsburgh, PA; Magee-Womens Research Institute, Pittsburgh, - - 2014
Studies using vital records-based maternal weight data have become more common, but the validity of these data is uncertain. We evaluated the accuracy of prepregnancy body mass index (BMI) and gestational weight gain (GWG) reported on birth certificates using medical record data in 1204 births at a teaching hospital in ...
Giannì M L ML Neonatal Intensive Care Unit, Department of Clinical Science and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, - - 2014
Early nutrition may affect body composition development. This study assessed body composition changes in healthy term infants in the first four months of life, comparing the results for breastfed and formula-fed babies. A longitudinal, observational study was conducted with healthy term infants, who had a birth weight of more than ...
Dritsakou K K NICU, Elena Venizelou Maternity - - 2014
Abstract Objective: Testing the validity of CRP in extremely low birth weight (ELBW) infants. Methods: During a five year period 483 infants with probable (36%) and definite sepsis (64%) were enrolled in the study. Results: ELBW infants with definitive sepsis had CRP levels comparable with full-terms. (p=0.992) However the highest ...
Ou Xiawei X Department of Radiology, University of Arkansas for Medical Sciences, Little Rock, AR, USA, - - 2014
Permissive hypercapnia is a ventilatory strategy used to prevent lung injury in ventilated extremely low birth weight (ELBW, birth weight ≤1,000 g) infants. However, there is retrospective evidence showing that high CO2 is associated with brain injury. The objective of this study was to compare brain white matter development at term-equivalent ...
Vidovics Mia M Paracelsus Medical University (PMU), Müllner Hauptstr. 48, 5020, Salzburg, - - 2014
To compare the fetal outcome of preterm breech infants delivered vaginally (VD) or by cesarean section (CS). A monocentric, retrospective consecutive case series of preterm breech deliveries between 24-37 gestational weeks over 10 years from 1/2000 to 12/2009 was performed in a perinatal care center (Level 1) at the University Clinic ...
Douglas S L SL School of Agriculture Food and Rural Development, Newcastle University, Newcastle upon Tyne, NE1 7RU, - - 2014
Performance of pigs from birth to slaughter is a result of a complex interaction of factors, with the early stages of a pig's life likely to affect lifetime performance. During the pre-weaning stage, piglets are reliant on the sow for nutrition, and sibling competition is likely to affect growth, in ...
Gale Christopher C Section of Neonatal Medicine, Chelsea and Westminster Hospital campus, Imperial College London, London, - - 2014
Background:Direct measurement of adipose tissue using magnetic resonance imaging (MRI) is increasingly used to characterize infant body composition. Optimal techniques for adjusting direct measures of infant adipose tissue remain to be determined.Objectives:To explore the relationships between body size and direct measures of total and regional adipose tissue (AT), and the ...
Peter Corinna C 1Hanover Medical School, Hanover, - - 2014
Objective. There is no consensus on prescription of home oxygen therapy to infants in Germany. We hypothesized that this causes considerable variability in prescribing home oxygen to infants. Study Design. A structured questionnaire involving management of home oxygen therapy was sent to all German pediatric departments (n = 293). Results. ...
Gross Rachel S RS 1 Department of Pediatrics, Albert Einstein College of Medicine, Children's Hospital at Montefiore , Bronx, - - 2014
Abstract Background: Although disparities in child obesity exist during infancy, the underlying mechanisms are unclear. Assessing dissimilarities in feeding practices, styles, and beliefs may provide a better understanding of these mechanisms. This study sought to identify modifiable maternal-infant feeding behaviors that may contribute to disparities in early child obesity. Methods: ...
Simonazzi Giuliana G Department of Medical Surgical Sciences, Division of Obstetrics and Prenatal Medicine, St. Orsola Malpighi Hospital, University of Bologna, Bologna, - - 2014
To evaluate the incidence of infants with birth weight less than the 10(th) centile for gestational age (SGA) in primary maternal cytomegalovirus (CMV) infection and to determine whether SGA predicts poor neurodevelopmental outcome. A retrospective cohort study, which included singleton liveborn infants from pregnancies complicated by primary maternal CMV infection. ...
van de Lagemaat Monique M Department of Pediatrics, VU University Medical Center, Amsterdam, The - - 2014
To identify growth-related collagen and bone parameters in small-for-gestational-age (SGA) and appropriate-for-gestational-age (AGA) preterm infants during the first six months post-term. In SGA preterm infants, increased growth and decreased bone acquisition, which we demonstrated previously, may be reflected by these markers. Observational study within a randomized controlled trial. Thirty-three SGA ...
van Ganzewinkel C C Máxima Medical Centre, Department of Pediatrics, division of Neonatology, Veldhoven, The - - 2014
The therapeutic options available to treat neonatal pain are limited and one alternative for non-opioid systemic treatment is paracetamol. However, pharmacokinetic data from prolonged administration of intravenous paracetamol in neonates are limited. The aim of this study was to present pharmacokinetics after multiple dose of intravenous paracetamol in very preterm ...
Bloom Michael S MS Department of Environmental Health Sciences, University at Albany, State University of New York, Rensselaer, NY USA; Department of Epidemiology and Biostatistics, University at Albany, State University of New York, Rensselaer, NY USA. Electronic address: - - 2014
Inorganic arsenic (iAs) is a human toxicant to which populations may be exposed through consumption of geogenically contaminated groundwater. A growing body of experimental literature corroborates the reproductive toxicity of iAs; however, the results of human studies are inconsistent. Therefore, we conducted a comprehensive review of epidemiologic studies focused on ...
Kumar Ashok A Division of Neonatology, Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India, - - 2014
Thymus is essential for immunity as it provides environment for T cell differentiation and maturation. There is limited information on various factors which determine thymic size at birth. We studied the influence of cord blood zinc and copper levels and maternal and neonatal nutritional status on thymic size in term ...
Shih Erin M EM Center for Endocrinology, Diabetes, and Metabolism, Children's Hospital Los Angeles, Los Angeles, CA. Electronic address: - - 2014
Hypospadias is one of the most common congenital malformations, affecting about 4-6 males per 1,000 male births, and ranging in severity from a urethral meatus that is slightly off-center to a meatus in the perineal area. Over the past three decades its prevalence may have increased due to changes in ...
Cekmez Y Y Department of Obstrectic and Gynecology, Sami Ulus Medical and Research Hospital, 34090, Ankara, Turkey, - - 2014
This study was performed to investigate the role of first-hour 50-g oral glucose challenge test (GCT) parameters in predicting the risk of delivering a small-for-gestational-age infant and to determine the accuracy of estimated fetal weight. We screened 2,643 pregnant women >20 years of age and excluded 552 patients according to exclusion ...
Giannì Maria Lorella - - 2014
Preterm infants are at risk for adverse neurodevelopment. Furthermore, nutrition may play a key role in supporting neurodevelopment. The aim of this study was to evaluate whether a nutrient-enriched formula fed to preterm infants after hospital discharge could improve their neurodevelopment at 24 months (term-corrected age). We conducted an observer-blinded, ...
Shan Xiaoyi - - 2014
Information tracking changes of birthweight is scarce in China. To examine trends of low birthweight (birthweight <2500 g) and macrosomia (birthweight >=4000 g) and potential risk factors in Beijing, hospital records from two major obstetrics and gynecology hospitals in urban districts in Beijing were analyzed. Hospital records from 1996 to ...
Jensen Erik A EA Division of Neonatology, The Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, - - 2014
Bronchopulmonary dysplasia (BPD) is among the most common and serious sequelae of preterm birth. BPD affects at least one-quarter of infants born with birth weights less than 1500 g. The incidence of BPD increases with decreasing gestational age and birth weight. Additional important risk factors include intrauterine growth restriction, sepsis, ...
Fonseca Maria João MJ Institute of Public Health, University of Porto, Porto, - - 2014
Newborn weight loss (NWL) in the first 3 days of life is around 6 percent of birthweight (BW). We aim to describe the determinants of an excessive and insufficient NWL in the first 96 hours of life. A sample of 1,288 full-term singletons without congenital abnormality belonging to Generation XXI birth cohort ...
Nakano Yuya Y Department of Pediatrics, Showa University School of Medicine, Tokyo, Japan. Electronic address: - - 2014
Preterm infants have altered fat tissue development, including a higher percentage of fat mass and increased volume of visceral fat. They also have altered adiponectin levels, including a lower ratio of high-molecular-weight adiponectin (HMW-Ad) to total adiponectin (T-Ad) at term-equivalent age, compared with term infants. The objective of this study ...
Heimann K K Department of Neonatology, University Hospital Aachen, - - 2014
Feeding tolerance and the degree of abdominal distension are important factors on the ward round on a NICU. They are basis for systematic changes in enteral feeds and an early indicator of clinical deterioration. Our aim was to examine the ratio of abdominal circumference (AC) to body weight (BW) as ...
Badon Sylvia E SE Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, - - 2014
Objective: Examine associations between gestational weight gain (GWG) exceeding Institute of Medicine (IOM) guidelines and neonatal adiposity in the five North American field centers of the Hyperglycemia and Adverse Pregnancy Outcome study. Design and Methods: GWG was categorized as less than, within, or greater than 2009 IOM guidelines. Birthweight, body ...
Olhager Elisabeth E Division of Paediatrics, Department of Clinical and Experimental Medicine, Faculty of Health Science, Linkoping University, SE-581 85, Linköping, - - 2014
To investigate changes in body weight, fat-free mass, fat mass and percentage of body fat during early life and at full-term post-conceptional age (PCA) in preterm infants born after 32 gestational weeks and before 37. Twenty-nine late preterm infants underwent growth and body composition assessment by air displacement plethysmography (ADP) ...
Inostroza Jaime J *Department of Basic Sciences, Universidad de La Frontera, Temuco, Chile †Nestlé Nutrition Institute, Vevey, Switzerland, and the Medical University of Vienna, Austria ‡Nestlé R&D, Nestec Ltd., Vevey, Switzerland §Department of Pediatrics, University of Iowa, Iowa City, - - 2014
Infant formulas provide more protein than breast milk. High protein intakes, as well as maternal obesity, are risk factors for later obesity. The present study tested whether a formula with lower protein content slows weight gain of infants of overweight mothers (BMI>25). In a randomized double-blind study infants of overweight ...
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