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Kaddourah Ahmad A Center for Acute Care Nephrology, Cincinnati Children's Hospital Medical Center (CCHMC), MLC 7022, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, - - 2014
The incidence of acute kidney injury (AKI) has steadily increased in the last decade in neonates and infants. Despite the extensive proposed pharmacologic approaches to treat or prevent AKI, renal replacement therapy is the only available therapeutic approach to manage the consequences of significant AKI and maintain electrolyte homeostasis and ...
Thong Kah Mean KM Kidney Genetics Group, Academic Nephrology Unit, University of Sheffield Medical School, Sheffield, UK Sheffield Kidney Institute, Sheffield Teaching Hospitals Foundation Trust, Sheffield, - - 2014
Intracranial aneurysm rupture is the most serious and potentially lethal extra-renal manifestation of autosomal dominant polycystic kidney disease (ADPKD). Almost all cases of ruptured intracranial aneurysm occur in adult patients with a median age of rupture of 40 years. We report the occurrence of sudden death in a newborn infant ...
Crobe Alessandra A University of Cagliari - - 2014
Nephron number at birth has a relevant clinical importance with implications for long-term renal health. In recent years, the podocyte depletion hypothesis has emerged as an important concept in kidney pathology. This study was aimed at verifying if human podocyte number changes significantly during intrauterine life. To this end, sixty-two ...
Girotto Neva - - 2014
The purpose of this study was to evaluate renographic parameters obtained from healthy renal units (RUs) in newborns and infants with unilateral kidney condition. Thirty three children including twenty newborns, referred to Technetium-99m mercaptoacetyltriglycine (Tc-99m MAG3) diuretic scintigraphy due to unilateral kidney condition entered the study. Only contralateral, healthy RUs ...
Werner Erika F - - 2012
To compare neonatal outcomes by method of delivery in preterm (34 weeks of gestation or prior), small-for-gestational-age (SGA) newborns in a large diverse cohort. Birth data for 1995-2003 from New York City were linked to hospital discharge data. Data were limited to singleton, liveborn, vertex neonates delivered between 25 and ...
Yonkers Kimberly A KA Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA. - - 2012
Major depressive disorder and the use of serotonin reuptake inhibitors (SRIs) in pregnancy have been associated with preterm birth. Studies that have attempted to separate effects of illness from treatment have been inconclusive. We sought to explore the separate effects of SRI use and major depressive episodes in pregnancy on ...
Costantine Maged M MM Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas, USA. - - 2012
To estimate the associations between polymorphisms in neuronal homeostasis, neuroprotection, and oxidative stress candidate genes and neurodevelopmental disability. This was a nested case-control analysis of a randomized trial of magnesium sulfate administered to women at imminent risk for early (before 32 weeks) preterm birth for the prevention of death or ...
Adinma Echendu Dolly - - 2012
Abstract Objective: To evaluate the maternal and perinatal outcome in patients with Eclampsia at Nnamdi-Azikiwe-University-Teaching-Hospital (NAUTH), Nnewi, Nigeria. Method: A retrospective study of cases of Eclampsia managed at NAUTH over a ten year period - 1(st) January, 2000 to 31(st) December, 2009. Maternal outcome was measured in terms of complications ...
Tully Kristin P - - 2012
Background: Postnatal unit rooming-in promotes breastfeeding. Previous research indicates that side-cars (3-sided bassinets that lock onto the maternal bed frame) facilitate breastfeeding after vaginal birth more than stand-alone bassinets (standard rooming-in). No study has previously investigated side-car bassinet use after cesarean, despite the constraints on maternal-infant interactions that are inherent ...
Macarthur Carol J - - 2012
PURPOSE OF REVIEW: To review the current literature on prenatal diagnosis of cervicofacial anomalies that may require neonatal intervention or that require prenatal counseling by a maternal-fetal medicine team and otolaryngology, head and neck surgery. RECENT FINDINGS: Ultrasound and MRI imaging are complementary in the prenatal diagnosis of fetal anomalies ...
Broussard Cheryl S - - 2012
OBJECTIVE:Birth defects are a leading cause of infant mortality in the United States. Previous reports have highlighted black-white differences in overall infant mortality and infant mortality attributable to birth defects (IMBD). We evaluated the impact of gestational age on US racial/ethnic differences in IMBD.METHODS:We estimated the rate of IMBD (using ...
Patel Sonali S - - 2012
Although the descriptive epidemiology of atrioventricular septal defects (AVSDs), a group of serious congenital heart defects (CHDs), has been recently reported, non-genetic risk factors have not been consistently identified. Using data (1997-2005) from the National Birth Defects Prevention Study, an ongoing multisite population-based case-control study, the association between selected non-genetic ...
Alleman Brandon W - - 2012
Preterm delivery (PTD) is the leading cause of neonatal morbidity and mortality. Epidemiologic studies indicate recurrence of PTD is maternally inherited, creating a strong possibility that mitochondrial variants contribute to its etiology. This study examines the association between mitochondrial genotypes and PTD and related outcomes. This study combined, through meta-analysis, ...
Etheredge Analee J - - 2012
Neural tube defects (NTDs) are common, serious malformations with a complex etiology that suggests involvement of both genetic and environmental factors. The authors evaluated maternal or offspring folate-related gene variants and interactions between the gene variants and maternal intake of folates on the risk of NTDs in their offspring. A ...
Saliho─člu Ozgül - - 2012
Aim:  The aim of this study was to determine the frequency, risk factors and anthropometric measurements of fetally malnourished, liveborn singleton term neonates. Methods:  The computed delivery room data of 11.741 liveborn singleton term neonates was used to compare malnourished and nourished newborns. Results:  Of the total subjects, 577 (4.9%) ...
de Wit S - - 2012
Objective:To compare mothers' and clinicians' understanding of an infant's illness and perceptions of discussion quality in the neonatal intensive care unit.Study Design:English-speaking mothers with an infant admitted to the intensive care unit for at least 48 h were interviewed using a semi-structured survey. The clinician whom the mother had spoken to ...
Loibl Sibylle S German Breast Group, Neu-Isenburg, Germany. - - 2012
Little is known about the treatment of breast cancer during pregnancy. We aimed to determine whether treatment for breast cancer during pregnancy is safe for both mother and child. We recruited patients from seven European countries with a primary diagnosis of breast cancer during pregnancy; data were collected retrospectively if ...
Langli Ersdal Hege - - 2012
Background: Intermittent fetal heart rate (FHR) monitoring during labor using an acoustic stethoscope is the most frequent method for fetal assessment of well-being in low- and middle-income countries. Evidence concerning reliability and efficacy of this technique is almost nonexistent. Objectives: To determine the value of routine intermittent FHR monitoring during ...
Rickard Ian J IJ Department of Animal and Plant Sciences, University of Sheffield, Sheffield S10 2TN, UK. - - 2012
Environmental conditions experienced in early life can influence an individual's growth and long-term health, and potentially also that of their offspring. However, such developmental effects on intergenerational outcomes have rarely been studied. Here we investigate intergenerational effects of early environment in humans using survey- and clinic-based data from rural Gambia, ...
Costantine Maged M MM Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas, USA. - - 2013
To compare population versus customized fetal growth norms in identifying neonates at risk for adverse outcomes (APO) associated with small for gestational age (SGA). Secondary analysis of an intrapartum fetal pulse oximetry trial in nulliparous women at term. Birth weight percentiles were calculated using ethnicity- and gender-specific population norms and ...
French Gina M - - 2012
To evaluate the effect of 2 anticipatory guidance styles (maternal focused [MOMS] and infant focused [Ounce of Prevention]) directed at mothers of infants aged newborn to 6 months on their infant feeding behaviors at 1 year compared with routine advice as outlined in Bright Futures (BF). This is a cluster ...
Khoshnood Babak - - 2012
OBJECTIVE: To assess the prevalence, timing of diagnosis and infant mortality of congenital heart defects (CHD) with population-based data and using a classification that allows regrouping of the International Paediatric and Congenital Cardiac Code into a manageable number of categories based on anatomic and clinical criteria (ACC-CHD). DESIGN: Population-based cohort ...
Lorch Scott A SA Department of Pediatrics, The Children's Hospital of Philadelphia and Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA 19104, USA. - - 2013
To define the association between large-scale obstetric unit closures and relative changes in maternal and neonatal outcomes. Birth and death certificates were linked to maternal and neonatal hospital discharge records for all births between January 1, 1995 and June 30, 2005 in Philadelphia, which experienced the closure of 9 of ...
Dahlen Hannah G - - 2012
BACKGROUND: the option of giving birth in water is available to most women in birth centres in Australia but there continues to be resistance in mainstream delivery wards due to safety concerns. Women in birth centres are more likely to give birth in upright positions and be attended by experienced ...
Bassil Kate L - - 2012
Objective To examine the relationship between area-level material deprivation and the risk of congenital anomalies in infants admitted to neonatal intensive care units (NICUs) across Canada.Study Design The Canadian Neonatal Network database was used to identify admitted infants who had congenital anomalies between 2005 and 2009. The association between congenital ...
Klauser Chad K - - 2012
Abstract Objective: Detail adverse neonatal effects in pregnancies treated with indomethacin (I), magnesium sulfate (M), or nifedipine (N). Methods: Women in acute preterm labor with cervical dilatation 1-6cm were randomized to receive one of three first line tocolytic drugs. Results: There were 317 neonates (I=103, M=95, N=119) whose mothers were ...
Ramon-Casas M - - 2012
BACKGROUND: Several studies have shown impaired neurocognitive development in infants born very preterm. Language is one of the areas that may be affected. Early lexical development measurements have revealed possible delays associated with low gestational age, but no studies have analyzed lexical processing using real-time measures in this at-risk population. ...
Kamath-Rayne Beena D - - 2013
To examine the differences in postneonatal death risk among 3 clinical subtypes of preterm birth: preterm premature rupture of membranes (PROM), indicated preterm birth, and spontaneous preterm labor. We analyzed the 2001-2005 US linked birth/infant death (birth cohort) datasets. The preterm birth subtypes were classified using information on the birth ...
Bhutta Zulfiqar A - - 2012
There has been increasing awareness over recent years of the persisting burden of worldwide maternal, newborn, and child mortality. The majority of maternal deaths occur during labor, delivery, and the immediate postpartum period, with obstetric hemorrhage as the primary medical cause of death. Other causes of maternal mortality include hypertensive ...
Piteo A M - - 2012
BACKGROUND: Previous research has linked family sleep disruption and dysfunction in children; however, the mechanism is unknown. AIMS: This study examined whether maternal sleep and postnatal depression (PND) mediate the relationship between infant sleep disruption and family dysfunction. STUDY DESIGN AND PARTICIPANTS: Mothers of infants aged 12months old (N=111; 48% ...
Bukulmez Aysegul - - 2012
Objective Fetal calprotectin levels increase in the early stages of necrotizing enterocolitis. Although the effects of several factors on fetal calprotectin have been studied, the effect of phototherapy is not known. In this study, we analyzed the effect of phototherapy on fetal calprotectin levels.Methods Ninety breast-fed newborns (46 male, 44 ...
Bos Lisanne T - - 2012
Dyslexia is characterized as a specific deficit of reading acquisition. It is one of the most common learning disabilities, persists throughout life, and can have a major impact on someone's socioeconomic success in our knowledge society. Preterm birth is associated with an increased risk of developmental problems including reading disabilities ...
Sallmon Hannes - - 2012
BACKGROUND:Experimental studies suggest that platelet-triggered ductal sealing is critically involved in definite ductus arteriosus closure. Whether thrombocytopenia contributes to persistently patent ductus arteriosus (PDA) in humans is controversial. This was a retrospective study of 1350 very low birth weight (VLBW; <1500 g) infants, including 592 extremely low birth weight (ELBW; ...
Medoff Cooper Barbara - - 2012
OBJECTIVE: To describe the neonatal health risks (hypothermia, hypoglycemia, hyperbilirubinemia, respiratory distress, the need for a septic workup, and feeding difficulties) experienced by late preterm infants (LPIs) from a large multisite study and determine how these risks were affected by gestational age at birth. DESIGN: Descriptive analysis of prospective data ...
Verropoulou Georgia - - 2012
Summary The present study aims at modelling the effects of maternal socio-demographic characteristics on the birth weight distribution in Greece. The analysis is based on nationwide vital registration micro-data; 103,266 single live births recorded in 2006 are considered. Quantile regression models, allowing for the effects of covariates to vary across ...
Dietz Patricia M - - 2012
The objective of the study was to assess if small- and large-for gestational age term infants have greater health care utilization during the first year of life. The sample included 28,215 singleton term infants (37-42 weeks) without major birth defects delivered from 1998 through 2007 and continuously enrolled at Kaiser Permanente ...
Salihu Hamisu M - - 2012
To examine the association between small for gestational age (SGA) in the first pregnancy and risk for infant mortality in the second pregnancy. This is a population-based, retrospective cohort study in which we used the Missouri maternally linked cohort dataset for 1978-2005. Analyses were restricted to women who had two ...
Williams I A - - 2012
The purpose of this study was to investigate early markers of risk for neurobehavioral compromise in survivors with congenital heart disease (CHD). Pregnant women in whom a fetal CHD had been diagnosed before 24 weeks' gestational age (GA) were enrolled in this prospective pilot study for serial Doppler ultrasound assessment ...
Kumar Amanika - - 2012
: Spontaneous umbilical cord vascular rupture is a rare event and historically has led to rapid neonatal demise. This catastrophic event has a small window of opportunity in which intervention may prevent neonatal death. : A 32-year-old multigravid woman's prenatal care was complicated by fetal anomalies, including a two-vessel cord ...
Bolch Christie E - - 2012
Multiple birth remains prevalent, with prematurity and subsequent disability being common complications. However, little is known of the experiences of mothers living with the combined circumstances of multiple birth, prematurity, and special needs. This paper reports an exploratory study using the qualitative technique of thematic analysis, to describe and interpret ...
Elliott-Carter Neva - - 2012
Keeping mothers and newborns together during the time immediately following delivery has several benefits, including the promotion of maternal-infant bonding and breastfeeding, which are essential components of care. A new care delivery model was instituted at a large women's health hospital so that women who delivered by cesarean were able ...
Khan Muhammad R - - 2012
The low gestational ages and morbidities of premature neonates in neonatal intensive care units exert a significant impact on neurodevelopmental outcomes. This longitudinal cohort study assessed the neurodevelopmental status of premature neonates after discharge from neonatal intensive care units in resource-limited countries such as Pakistan. Developmental assessment involved the Denver ...
Guillén Ursula - - 2012
Our objective was to survey neonatologists regarding international practice of red cell transfusion thresholds for premature infants with <1000-g birth weight and/or <28-week gestation. An invitation to fill out an 11-question web-based survey was distributed to neonatologists through their professional societies in 22 countries. Physicians were asked about which specific ...
Kondaurova Maria V - - 2012
Recent studies have demonstrated that mothers exaggerate phonetic properties of infant-directed (ID) speech. However, these studies focused on a single acoustic dimension (frequency), whereas speech sounds are composed of multiple acoustic cues. Moreover, little is known about how mothers adjust phonetic properties of speech to children with hearing loss. This ...
Lloreda-García Jose María - - 2012
A 29 years-old primiparous woman presented with spontaneous pregnancy.Ultrasound performed at 29 weeks of gestation showed a thickened placenta with hypoechoic areas, umbilical vein dilatation and 2 hepatic masses in the fetus. Maternal infections for toxoplasma, rubella, syphilis, herpes, cytomegalovirus and parvovirus B19 were ruled out. At 31 weeks of ...
Chaudhari Tejasvi - - 2012
Urinary ascites in a newborn infant is unusual and most commonly results from bladder perforation following umbilical arterial catheterisation or obstructive uropathy. The following report describes a case of fetal bladder rupture with urinary ascites in a mother ventilated and sedated with narcotics and benzodiazepines for H1N1 influenza. This was ...
Yang Wei W Department of Pediatrics, Stanford University, Stanford, California, USA. - - 2012
Limited information is available about the association of maternal weight gain during pregnancy and birth defects. The objective of this study was to investigate the association of maternal weight gain with neural tube defects (NTDs) and gastroschisis among offspring. We used data from the National Birth Defects Prevention Study, an ...
Nanduri Jayasri J Institute for Integrative Physiology and Center for Systems Biology of O(2) Sensing, Biological Science Division, University of Chicago, Chicago, - - 2013
Recurrent apnea with intermittent hypoxia (IH) is a major clinical problem in infants born preterm. Carotid body chemo-reflex and catecholamine secretion from adrenal medullary chromaffin cells (AMC) are important for maintenance of cardio-respiratory homeostasis during hypoxia. This article highlights studies on the effects of IH on O(2) sensing by the ...
Goldberg Wendy A WA Department of Psychology and Social Behavior, School of Social Ecology, University of California, Irvine, CA 92697, USA. - - 2013
Transactional models of parenting and infant sleep call attention to bidirectional associations among parenting, the biosocial environment, and infant sleep behaviors. Although night waking and bedtime fussing are normative during infancy and early childhood, they can be challenging for parents. The current study, conducted in the United States between 2003 ...
Salihu Hamisu M - - 2012
To examine the association between prior infant mortality and subsequent risk for small for gestational age (SGA). This population-based, retrospective cohort study used the Missouri maternally linked, longitudinal dataset (1989-2005). Analyses were restricted to women who had two singleton pregnancies during the study period. Logistic regression was conducted to obtain ...
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