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Hakeem Abdel H A A - - 2012
Retinopathy of prematurity (ROP) is a serious complication of prematurity treatment and can lead to blindness unless recognized and treated early. The objective was to estimate the prevalence of ROP in preterm infants in the Neonatal Intensive Care Unit (NICU), to identify the risk factors which predispose to ROP, and ...
Rosenstein Melissa G - - 2012
To estimate the multiple dimensions of risk faced by pregnant women and their health care providers when comparing the risks of stillbirth at term with the risk of infant death after birth. This is a retrospective cohort study that included all nonanomalous, term deliveries in the state of California from ...
Lawn Joy E - - 2012
Neonatal deaths account for 40% of global under-five mortality and are ever more important if we are to achieve the Millennium Development Goal 4 (MDG 4) on child survival. We applied a results framework to evaluate global and national changes for neonatal mortality rates (NMR), healthy behaviours, intervention coverage, health ...
Liu Ying Y School of Medicine, Duke University, Durham, NC, - - 2012
Depressed mood in pregnancy has been linked to low birth weight (LBW, < 2,500 g), a risk factor for adult-onset chronic diseases in offspring. We examined maternal depressed mood in relation to birth weight and evaluated the role of DNA methylation at regulatory sequences of imprinted genes in this association. ...
Yinon Yoav - - 2012
The purpose of this study was to determine whether corticosteroid administration after 34 weeks of gestation is associated with improved neonatal outcome in the presence of fetal lung immaturity. We conducted a retrospective cohort study of women who underwent amniocentesis to determine fetal lung maturity from 34-37 weeks of gestation. ...
Kennedy Holly Powell - - 2012
ABSTRACT: The mission of the American College of Nurse-Midwives (ACNM) is to promote the health and well-being of women and newborns within their families and communities through development and support of the profession of midwifery. The United Nations Millennium Development Goals 4 and 5 are to reduce infant and child ...
Collado Maria Carmen - - 2012
The role of human microbiota has been redefined during recent years and its physiological role is now much more important than earlier understood. Intestinal microbial colonization is essential for the maturation of immune system and for the developmental regulation of the intestinal physiology. Alterations in this process of colonization have ...
Vernooij-van Langen Annette M M - - 2012
BACKGROUND: Pancreatitis-associated protein (PAP) is currently discussed as a marker in newborn screening (NBS) for cystic fibrosis (CF). However, it is not known if PAP concentrations are influenced by sex, gestational age, birth weight, blood transfusion or time of collection and what this would mean for NBS for CF. METHODS: ...
Dogra Shivani - - 2012
This was a prospective observational study conducted in a level III neonatal unit in North India to measure the incidence of feed intolerance and necrotizing enterocolitis (NEC) in preterm small for gestational age (SGA) neonates with normal umbilical artery Doppler flow in comparison with gestation matched appropriate for gestational age ...
Aminzadeh Fariba - - 2012
BACKGROUND AND AIM: Pre-term delivery is a mostly unknown frequent disorder worldwide. This project aimed to investigate the circulating levels of CXCL12 (SDF-1) and CXCL10 (IP-10) in cord blood of term and pre-term delivered fetuses and their corresponding mothers. MATERIAL AND METHODS: Cord and peripheral blood samples were collected from ...
Gurevitz Mina - - 2012
Objective: Characterization of risk factors for ADHD in infancy may enable early intervention to diminish the symptoms that ensue. Method: In a retrospective study, the well-baby-care clinic records from birth to 18 months of age of 58 children diagnosed at school age for ADHD were compared with those of 58 ...
Sovio Ulla - - 2012
Background:  Infant mortality rates have fallen considerably in the past decades. However, because of sparseness of historical data, it is unclear how social differences in infant mortality have changed over time. Methods:  The aim of this study was to assess the association between prenatal social determinants and infant mortality in ...
Charafeddine Lama - - 2012
Background:  Consanguinity which increases the risk of genetic disorders has been implicated at times in infant mortality. The aim of this study was to determine the association between consanguinity and in-hospital mortality in newborns. Methods:  Data was collected prospectively on all births from 26 hospitals in Lebanon from January 2004 ...
Stein Aryeh D - - 2012
The evidence relating prenatal supplementation with DHA to offspring neurological development is limited. We investigated the effect of prenatal DHA supplementation on infant brainstem auditory-evoked responses and visual- evoked potentials in a double-blind, randomized controlled trial in Cuernavaca, Mexico. Pregnant women were supplemented daily with 400 mg DHA or placebo ...
Goo Leslie L Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, - - 2012
HIV-1 variants transmitted to infants are often resistant to maternal neutralizing antibodies (NAbs), suggesting that they have escaped maternal NAb pressure. To define the molecular basis of NAb escape that contributes to selection of transmitted variants, we analyzed 5 viruses from 2 mother-to-child transmission pairs, in which the infant virus, ...
Hanley Gillian E - - 2012
Understanding how prenatal serotonin reuptake inhibitors (SRIs) influence early brain development can provide critical clues to how early life experience programs developing neural systems that might contribute to risks for illness across the life span. To date, no gross SRI-related neuroteratogenic effects have been identified, but evidence of subtle functional ...
Yoshida Keiko - - 2012
The objectives of this study were (1) to develop a Japanese version of Mother-to- Infant Bonding Scale Japanese version (MIBS-J) based on Kumar's Mother Infant Bonding Questionnaire that could be used to screen the general population for problems in the mother's feelings towards her new baby and to validate it ...
Shin Mikyong - - 2012
OBJECTIVE: To evaluate trends in survival among children with spina bifida by race/ethnicity and possible prognostic factors in 10 regions of the United States. STUDY DESIGN: A retrospective cohort study was conducted of 5165 infants with spina bifida born during 1979-2003, identified by 10 birth defects registries in the United ...
Streimish Iris G - - 2012
The newborn classified as growth-restricted on fetal weight curves, but not on birth weight curves, is classified prenatally as small for gestational age (SGA), but postnatally as appropriate for gestational age (AGA). To see (1) to what extent the neurodevelopmental outcomes at 24 months corrected age differed among three groups ...
Beurskens Leonardus W J E - - 2012
Homocysteine is an intermediate of the one-carbon (1-C) pathway and increased concentrations have been related to neural crest-related congenital anomalies. The neural crest and the 1-C pathway might be involved also in the etiology of Congenital Diaphragmatic Hernia (CDH). In 22 CDH and 28 control newborns and their mothers, general ...
Chu Ching Yan - - 2012
Melamine can be transferred to fetus in utero through placenta and to infant ex utero by breast feeding. In this study, we characterized the pharmacokinetics of melamine in prenatal and postnatal organs in rats. Single bolus of melamine was administered to pregnant rats at different gestational stages and to infants ...
Yamada Sohsuke - - 2012
A male infant born prematurely at 31 weeks of gestation weighed 789 g and had mildly brown-colored oral/tracheal aspirates at delivery. The amniotic fluid was also discolored, and its index was below 5. The patient died of hypoxemic respiratory and cardiac failure 2 hours after birth. The maternal profiles showed placenta previa and ...
McLelland Gayle - - 2012
OBJECTIVES: the primary objective-to present data on the incidence of unplanned births before arrival (BBAs) in Victoria between 1991 and 2008. The secondary objective-to provide an extensive literature review highlighting the issues surrounding an unplanned BBA. SETTING: the incidence of BBAs in Victoria published in the relevant government reports. DESIGN: ...
Super Charles M - - 2012
The response of 185 infants to their mothers' departure was assessed in a rural area of Bangladesh. Despite their poor health and nutritional status, this group of infants showed the same peak in separation protest around the end of the first year that has been documented for healthier samples in ...
Wörmann Viktoriya - - 2012
Social smiling is universally regarded as being an infant's first facial expression of pleasure. Underlying co-constructivist emotion theories are the assumptions that the emergence of social smiling is bound to experiences of face-to-face interactions with caregivers and the impact of two developmental mechanisms - maternal and infant imitation. We analyzed ...
Suwalsky Joan T D - - 2012
Contingencies of three maternal and two infant socioemotional behaviors that are universal components of mother-infant interaction were investigated at 5 months in 62 mothers (31 who had adopted domestically and 31 who had given birth) and their first children (16 males in each group). Patterns of contingent responding were largely ...
Reddy Uma M - - 2012
We sought to study neonatal outcomes in early preterm births by delivery route. Delivery precursors were analyzed in 4352 singleton deliveries, 24 0/7 to 31 6/7 weeks' gestation. In a subset (n = 2906) eligible for a trial of labor, neonatal mortality in attempted vaginal delivery (VD) was compared to ...
Engin-Üstün Yaprak - - 2012
Abstract Objective: Population-based studies on maternal deaths in Turkey are rare. The aim of the present study was to analyze the cardiac causes of all maternal deaths in Turkey between 2007-2009. Materials-Methods: In this retrospective study, case files of all pregnancy-associated deaths recorded in Turkey between 2007 and 2009 were ...
Daley Amanda J - - 2012
BACKGROUND AND OBJECTIVES:Studies have revealed that women who breastfeed their infants may be reluctant to exercise due to concerns that to do so would adversely affect their breast milk and consequently the growth of their infants. In this review, we seek to systematically review and statistically synthesize evidence from randomized ...
Hinkle Stefanie N - - 2012
Gestational weight gain (GWG) is an important predictor of short- and long-term adverse maternal and child outcomes. As interest in long-term outcomes increases, utilization of maternal postpartum report is likely to also increase. There is little data available examining the reliability and identifying predictors of bias in GWG recalled by ...
Glangeaud-Freudenthal Nine M-C - - 2012
PURPOSE: Our aim was to investigate the factors associated with mother-child separation at discharge, after joint hospitalization in psychiatric mother-baby units (MBUs) in France and Belgium. Because parents with postpartum psychiatric disorders are at risk of disturbed parent-infant interactions, their infants have an increased risk of an unstable early foundation. ...
Finkton Darryl W DW - - 2012
Arab-Americans (AAs) have lower risk of preterm birth relative to Non-Arab Whites. This has been attributed to lower likelihood of birth out of wedlock, maternal tobacco use during pregnancy, and foreign maternal birthplace among AAs. We were interested in understanding the roles of these and other demographic factors in the ...
Widdows Kate - - 2012
BACKGROUND: Sudden infant death syndrome (SIDS) is postulated to be a developmental disorder originating during fetal life in utero. Knowledge regarding the intrauterine environment in which SIDS infants develop is, however, inadequate and how the placenta develops prior to a SIDS event has not been studied. AIM: To investigate the ...
Steehler Mark W - - 2012
OBJECTIVES: To measure maternal breast feeding benefit after infant frenotomy. To investigate if timing of neonatal/infant frenotomy affects outcome. STUDY DESIGN: Cohort survey and retrospective review. METHODS: Medical records of neonates and infants suspected to have ankyloglossia between April 2006 and February 2011 were reviewed. Patient demographic data was compiled. ...
Henry E - - 2012
Objective:The best practices for the care of a neonate born after a tight nuchal cord have not been defined. As a step toward this, we compared the outcomes of neonates born after a tight nuchal cord vs those born after a loose nuchal cord vs those born after no nuchal ...
Källén Bengt B University of Lund, Lund, Sweden. - - 2013
An association between preterm birth and an increased risk of childhood asthma has been demonstrated, but the importance of intrauterine growth retardation on asthma risk is unclear. Using data from Swedish health registers, infant characteristics and childhood asthma were studied. Analyses were made using Mantel-Haenszel methodology with adjustment for year ...
Katon Jodie - - 2012
To determine if, among overweight or obese women with gestational diabetes (GDM), weight loss after GDM diagnosis is associated with lower infant birth weight within levels of overweight or obesity class. Overweight and obese women with singleton pregnancies managed for GDM at a large diabetes and pregnancy program located in ...
Rootwelt V - - 2012
Intrapartum death in multiparous gestations in sows is often caused by hypoxia. There is little information in the literature on the assessment of the placenta in relation to intrapartum death in piglets.The aim of this study was to evaluate the impact of the placental area and weight upon piglet birth ...
Waffarn Feizal F Department of Pediatrics and the Women and Children's Health and Wellbeing Project, University of California-Irvine, Orange, CA, USA. - - 2012
The hypothalamic-pituitary-adrenocortical (HPA) axis is a major neuroendocrine pathway that modulates the stress response. The glucocorticoid, cortisol, is the principal end product of the HPA axis in humans and plays a fundamental role in maintaining homeostasis and in fetal maturation and development. Antenatal administration of synthetic glucocorticoids (GCs) accelerates fetal ...
Bekker A - - 2012
BACKGROUND: Maternal and neonatal tuberculosis (TB) are under-recognised, particularly in settings with a high burden of human immunodeficiency virus (HIV) infection.DESIGN AND SETTING: Retrospective audit of neonates routinely screened for TB in a South African hospital during 2009. Surveillance sources reviewed included routine clinical, laboratory and pharmacy records.RESULTS: Among 70 ...
Makrides Maria - - 2012
A dietary supply of docosahexaenoic acid (DHA, 22:6n-3) during the perinatal period is postulated to be important for the neurodevelopmental outcome of children. This paper reviews the results of two large scale intervention trials in which equivalent dietary doses of DHA were assessed. One trial assessed the ex utero effect ...
Edwards Bradley A - - 2012
Any general model of respiratory control must explain a puzzling array of breathing patterns that are observed during the course of a lifetime. Particular challenges are to understand why periodic breathing is rarely seen in the first few days after birth, reaches a peak at 2-4 weeks postnatal age, and ...
Brummelte S - - 2012
This study was undertaken to determine whether altered early serotonin signaling either via gestational serotonin reuptake inhibitor (SRI) exposure or genetic variations in the serotonin transporter promoter region (SLC6A4) alters levels of reelin, an important glycoprotein in neurodevelopment, in mothers and their neonates. Serum reelin protein expression was quantified by ...
Downard Cynthia D - - 2012
BACKGROUND:The maternal variables that affect fetal development and correlate with necrotizing enterocolitis (NEC), the most common gastrointestinal emergency in premature infants, are not well defined. We hypothesized that maternal risk factors were the primary determinant of future development of NEC.METHODS:Patients with NEC were identified from an established NICU database and ...
Díaz Marta - - 2012
Background and Objective:The nuclear receptor peroxisome proliferator activated receptor γ (PPARγ) contributes to placental development and thus to the maternofetal transfer of oxygen and nutrients that allow for prenatal growth. We tested the hypothesis that placental PPARγ expression relates to placental and fetal growth.Design and Study Population:Placentas (n = 116) ...
Monique H O - - 2012
Abstract Objective: Determine whether elevated second trimester maternal serum alpha-fetoprotein (AFP) is associated with clinical and histopathologic markers of inflammation at preterm delivery. Methods: 105 women <32 weeks' gestation were included. AFP levels were dichotomized at 2.0 multiples of the median (MoM). Rates of neonatal morbidities, clinical chorioamnionitis, cord blood ...
Cruz-Martinez Rogelio - - 2012
Objective: To explore the potential value of intrapulmonary Doppler in predicting neonatal morbidity in fetuses with left-sided congenital diaphragmatic hernia (CDH) treated with fetoscopic tracheal occlusion (FETO). Methods: Observed/expected lung to head ratio (O/E LHR) and intrapulmonary Doppler Pulsatility Index (PI) and Peak Early Diastolic Reverse Flow (PEDRF) were evaluated ...
Simard Marie-Noëlle - - 2012
BACKGROUND:Although preterm infants born at 29 to 36 gestational weeks (GW) are at risk for developmental delay, they do not always benefit from systematic follow-up. Primary care physicians are then responsible for their developmental surveillance and need effective screening tests. This study aimed to determine whether the Ages and Stages ...
Smith Lucy - - 2013
To investigate regional variation in the registration of preterm births <24 weeks of gestation and the impact on infant death rates for English Primary Care Trusts (PCTs). Cohort study. England. All registered births (1 January 2005-31 December 2008) by gestational age and PCT (147 trusts) linked to infant deaths (up ...
Stolzenberg Danielle S - - 2012
The quality and quantity of maternal care received during infancy are highly predictive of successful infant development. It has been well established, primarily in rats, that the combination of hormonal and infant stimuli at birth modifies neural circuits that regulate maternal responsiveness. During subsequent interactions, infant stimuli are more likely ...
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