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Proietti Elena E Inselspital and University of Bern, Bern, - - 2014
Compared with term-born infants, preterm infants have increased respiratory morbidity in the first year of life. We investigated whether lung function tests performed near term predict subsequent respiratory morbidity during the first year of life and compared this to standard clinical parameters in preterms.The prospective birth cohort included randomly selected ...
Sierra Carlos C Hospital Materno-Infantil, Avda. Arroyo de los Ángeles s/n, 29011, Málaga, - - 2014
Currently, there is no consensus concerning the possible beneficial colonic and systemic effects of prebiotic-containing infant formula. This study assesses whether the feeding of a galactooligosaccharides (GOS)-containing infant formula (0.44 g/dl of GOS) and the subsequent feeding of a GOS-containing follow-on formula (0.50 g/dl of GOS) have a prebiotic effect on intestinal ...
Hasenstab Kathryn A KA The Neonatal and Infant Feeding Disorders Program, Center for Perinatal Research, Nationwide Children's Hospital Research Institute, Columbus, - - 2014
To test the hypothesis that proximal aerodigestive clearance mechanisms mediated by pharyngoesophageal motility during spontaneous respiratory events (SREs) are distinct in infants with apparent life threatening events (ALTEs). Twenty infants (10 with proven ALTE, 10 healthy controls) had pharyngoesophageal manometry to investigate motility changes concurrent with respiratory events detected by ...
Yap Gaik Chin - - 2014
Studies have suggested that selective microbial targets prevail in the fecal microbiota of infants with eczema. This study evaluated the composition of fecal microbiota of infants who developed eczema in the first 5 years of life and compared these with those of healthy controls. Children who developed eczema in the ...
Parravicini E E Division of Neonatology, Department of Pediatrics, Morgan Stanley Children's Hospital of NewYork-Presbyterian, Columbia University Medical Center, New York, NY, - - 2014
Objective:To describe the neonatal outcomes of a case series of infants who were prenatally diagnosed with potential life-limiting conditions and to whom individualized comfort measures were offered.Study Design:This is a retrospective analysis of the postnatal outcomes of a selected population of 49 infants prenatally diagnosed with potential life-limiting conditions whose ...
Ogden Thomas H TH 306 Laurel Street, San Francisco, CA, 94118, USA. - - 2014
Winnicott's Fear of breakdown is an unfinished work that requires that the reader be not only a reader, but also a writer of this work which often gestures toward meaning as opposed to presenting fully developed ideas. The author's understanding of the often confusing, sometimes opaque, argument of Winnicott's paper ...
Rais-Bahrami Khodayar K Department of Neonatology, Children's National Medical Center, The George Washington University School of Medicine, 111 Michigan Ave, NW, Washington, DC 20010. Electronic address: - - 2014
Extracorporeal membrane oxygenation (ECMO) continues to be an important rescue therapy for newborns with a variety of causes of cardio-respiratory failure unresponsive to high-frequency ventilation, surfactant replacement, and inhaled nitric oxide. There are approximately 800 neonatal respiratory ECMO cases reported annually to the Extracorporeal Life Support Organization; venoarterial ECMO has ...
Mesher Andrew L AL Department of Surgery, University of Washington School of Medicine, Seattle, - - 2014
Extracorporeal life support is an important therapy for neonates with life-threatening cardiopulmonary failure. Utilization of extracorporeal life support in neonates with congenital heart disease has increased dramatically during the past three decades. Despite increased usage, overall survival in these patients has changed very little and extracorporeal life support-related morbidity, including ...
Del Vecchio Antonio A Division of Neonatology, Neonatal Intensive Care Unit, Di Venere Hospital, Bari, Italy. Electronic address: - - 2014
Neonatal sepsis is frequently accompanied by significant and sometimes life-threatening coagulopathy. More complete understanding is needed of the molecular and cellular mechanisms underlying the interaction of the inflammatory and hemostatic systems. Such information may help focus future studies toward novel ways to improve the outcome of neonates who develop septic ...
Kawamata Ryou - - 2014
Abstract Aim: To investigate changes of gut hormones in term and preterm infants in the first 2 months after birth, as the role and relationships of gut hormones in premature infants has not been well elucidated. Methods: In 29 preterm and five term infants, fasting serum concentrations of leptin, glucose-dependent ...
Chong Neto H J HJ Division of Pediatric Allergy and Immunology, Hospital de Clínicas, Federal University of Paraná, Curitiba, - - 2014
There are few published studies on prevalence of allergic rhinitis in preschool children. The aims of this study were to verify the prevalence, clinical characteristics, and treatment of allergic rhinitis (AR) symptoms in the first year of life adding supplementary questions to the EISL instrument. A cross-sectional study used Phase ...
Berglund Staffan S Department of Clinical Sciences, Pediatrics, Umeå University, Umeå, - - 2014
Iron deficiency early in life is associated with impaired neurological development. This study reviews the latest research on how to best meet iron requirements in infants and children. There is concurrent evidence that delayed cord clamping is well tolerated and improves infant iron stores. Iron supplements or enriched complementary foods ...
Farchi Sara - - 2014
The fetal and infant life are periods of rapid development, characterized by high susceptibility to exposures. Birth cohorts provide unique opportunities to study early-life exposures in association with child development and health, as well as, with longer follow-up, the early life origin of adult diseases. Piccolipiu is an Italian birth ...
Lorenz John M JM aDivision of Neonatology, College of Physicians and Surgeons, Columbia University bDivision of Pediatric Critical Care Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, - - 2014
To review the evolving management of infants/children with trisomy 18, the prognosis with and without medical intervention, the factors that have contributed to the evolving management strategies, and an approach to the formulation of healthcare management plans for newborns with trisomy 18. There has been a trend from nonintervention for ...
van Vonderen Jeroen J JJ Division of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, The - - 2014
The transition to life after birth is characterized by major physiological changes in respiratory and hemodynamic function, which are predominantly initiated by breathing at birth and clamping of the umbilical cord. Lung aeration leads to the establishment of functional residual capacity, allowing pulmonary gas exchange to commence. This triggers a ...
Charlton Jennifer R JR Department of Pediatrics, Division of Nephrology, University of Virginia, Box 800386, Charlottesville, VA, 22908, USA, - - 2014
Although there is wide variation, humans possess on average 900,000 nephrons per kidney. So far as is known, nephrons cannot regenerate; therefore, an individual's nephron endowment has profound implications in determining his or her long-term risk of developing chronic kidney disease. Most of the variability in human nephron number is ...
Reisner Gavriel G 55 West End Ave., #S15I, New York, NY 10023. E-mail: - - 2014
This article presents a revisionary reading of Freud's Beyond the Pleasure Principle. Recognizing the power of Freud's meditation on a universal "death-drive" in living organisms, it argues that Freud makes a greater contribution by strengthening the compulsion to repeat to a form of figurative death. We recall that after shattering ...
Wertheim David D Faculty of Science, Engineering and Computing, Kingston University, - - 2014
Non-invasive monitoring of breathing is a holy grail in paediatric respiratory, neonatal and sleep medicine. Respiratory rate is a key marker for the surveillance of sick infants and children (1-3), while repeated infant apnoeic episodes are associated with an increased risk of apparent life-threatening events (4). In clinical pulse oximetry, ...
Lloyd Patricia Calderón PC aDepartment of Epidemiology and Biostatistics, and bDepartment of Global Health, The George Washington University School of Public Health and Health Services, Washington, DC cDepartment of Emergency Medicine, The George Washington University Medical Faculty Associates, Washington, - - 2014
Respiratory syncytial virus (RSV) is the most common cause of severe respiratory illness in infants. To help direct targeted interventions and future RSV vaccine programs, we examined risk of RSV-related hospitalization by infant age and birth month. We conducted Poisson regression analyses to evaluate birth-month as a risk factor for ...
Cantrill Ruth M - - 2014
Best practice guidelines to promote breastfeeding suggest that (i) mothers hold their babies in naked body contact immediately after birth, (ii) babies remain undisturbed for at least one hour and (iii) breastfeeding assistance be offered during this period. Few studies have closely observed the implementation of these guidelines in practice. ...
Marr Nico N Department of Pediatrics, University of British Columbia and Children's and Women's Health Centre of British Columbia, Vancouver, British Columbia V6H 3V4, - - 2014
Newborn infants, including those born at term without congenital disorders, are at high risk of severe disease from respiratory syncytial virus (RSV) infection. Indeed, our current local surveillance data demonstrate that approximately half of children hospitalized with RSV were ≤3 mo old, and 74% were born at term. Informed by ...
Csont Georgia Lowmaster - - 2014
The revised standard of care for breastfeeding infants at risk of developing hypoglycemia during transitioning to extrauterine life was developed using the American Academy of Pediatrics (AAP) 2011 hypoglycemia guidelines, the Academy of Breastfeeding Medicine protocol, and staff input. A pre/postimplementation chart audit indicated support of infant safety by glucose ...
Singhal Atul A The Childhood Nutrition Research Centre, Institute of Child Health, University College London, London, - - 2014
The rapid increase in prevalence of noncommunicable diseases (NCDs) is probably the most important global health problem of the 21st century. Already in every region except Africa, NCDs account for greater mortality than communicable, maternal, perinatal and nutritional conditions combined. Although modifiable lifestyle behaviors in adult life are the main ...
Haig David D Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, - - 2014
Interbirth intervals (IBIs) mediate a trade-off between child number and child survival. Life history theory predicts that the evolutionarily optimal IBI differs for different individuals whose fitness is affected by how closely a mother spaces her children. The objective of the article is to clarify these conflicts and explore their ...
Sung Valerie V Royal Children's Hospital, Parkville, Victoria, - - 2014
To determine whether the probiotic Lactobacillus reuteri DSM 17938 reduces crying or fussing in a broad community based sample of breastfed infants and formula fed infants with colic aged less than 3 months. Double blind, placebo controlled randomised trial. Community based sample (primary and secondary level care centres) in Melbourne, ...
Pacifici Gian Maria GM Section of Pharmacology, Department of Translational Research and New Technologies in Medicine and Surgery, Medical School, University of Pisa, 56126 Pisa, - - 2014
Midazolam is a benzodiazepine with rapid onset of action and short duration of effect. In healthy neonates the half-life (t 1/2) and the clearance (Cl) are 3.3-fold longer and 3.7-fold smaller, respectively, than in adults. The volume of distribution (Vd) is 1.1 L/kg both in neonates and adults. Midazolam is hydroxylated ...
Rincón-Cortés Millie M Department of Neuroscience and Physiology, Sackler Institute for Graduate Biomedical Sciences, New York University School of Medicine , New York, NY , USA ; Emotional Brain Institute, Nathan Kline Institute for Psychiatric Research , New York, NY , USA ; New York University Child Study Center, Department of Child and Adolescent Psychiatry, New York University School of Medicine , New York, NY , - - 2014
Over half a century of converging clinical and animal research indicates that early life experiences induce enduring neuroplasticity of the HPA-axis and the developing brain. This experience-induced neuroplasticity is due to alterations in the frequency and intensity of stimulation of pups' sensory systems (i.e., olfactory, somatosensory, gustatory) embedded in mother-infant ...
Haig David D Department of Organismic and Evolutionary Biology, Harvard University, 26 Oxford Street, Cambridge, MA 02138, - - 2014
Disrupted sleep is probably the most common complaint of parents with a new baby. Night waking increases in the second half of the first year of infant life and is more pronounced for breastfed infants. Sleep-related phenotypes of infants with Prader-Willi and Angelman syndromes suggest that imprinted genes of paternal ...
Katheria Anup A Division of Neonatology, UCSD Medical Center, University of California San Diego, San Diego, California, United States of - - 2014
Umbilical cord milking (UCM) improves blood pressure and urine output, and decreases the need for transfusions in comparison to immediate cord clamping (ICC). The immediate effect of UCM in the first few minutes of life and the impact on neonatal resuscitation has not been described. Women admitted to a tertiary ...
Paviotti Giulia G Division of Neonatology, Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Via dell'Istria 65/1, 34137 Trieste, - - 2013
Background. Although twin gestation is well recognized to be associated with impaired fetal and postnatal growth, specific data about body composition of twins in the first month of life are scarce. Objective. The aim of this study was to compare the body composition of twins, evaluated with air-displacement plethysmography, to ...
Tinnion Robert R Department of Neonatal Medicine, Royal Victoria Infirmary, , Newcastle upon Tyne, - - 2013
The incidence of preterm birth is increasing worldwide. Evidence suggests that in later life these children are at increased risk of 'metabolic syndrome', which is itself associated with reduced insulin sensitivity (IS). We carried out a systematic review to examine whether preterm birth is associated with later changes in IS ...
Lusyati Setyadewi - - 2013
Novel methods for cytokine analysis allow for the simultaneous measurement of 25 cytokines in 50 muL serum or plasma. Data on values of most of these cytokines in non-infected newborn infants are lacking. We analyzed levels of 25 cytokines in the first week of life in non-infected preterm and term ...
Collins Jennifer J P JJ Ottawa Hospital Research Institute, Regenerative Medicine Program, 501 Smyth Road, Room CCW6.137, Ottawa, Ontario, Canada, K1H8L6 ; - - 2013
Significance: Bronchopulmonary dysplasia (BPD) is a disease of the developing lung that afflicts extreme preterm infants in the neonatal intensive care unit (NICU). Follow-up studies into adulthood show that BPD isn't merely a problem of the neonatal period, as it also may predispose to early-onset emphysema and poor lung function ...
Shapira Moshe M Maccabi Health Services, Nave Sha'anan Clinic/Pediatrics, Haifa, - - 2013
Oral mucoceles are common lesions that normally appear in the second decade of life. They are uncommon in neonates and infants. We present a case of a mucocele in a 10-month-old infant and review the literature regarding the epidemiology and treatment in this age group.
Traudt Christopher M CM Department of Pediatrics, University of Washington, Seattle, WA, - - 2013
Background:Cerebellar hypoplasia is common problem for preterm infants, and infants that suffer intraventricular hemorrhage (IVH). To evaluate the effects of IVH on cerebellar growth and development, we used a neonatal rabbit model of systemic glycerol to produce IVH.Methods:New Zealand White rabbit kits were surgically delivered 2 d preterm, and treated ...
Skerry Amy E - - 2013
Identifying the goal of another agent's action allows an observer to make inferences not only about the outcomes the agent will pursue in the future and the means to be deployed in a given context, but also about the emotional consequences of goal-related outcomes. While numerous studies have characterized the ...
O'Brien Frances - - 2013
The physiology of the neonate is ideally suited to the transition to extrauterine life followed by a period of rapid growth and development. Intravenous fluids and electrolytes should be prescribed with care in the neonate. Sodium and water requirements in the first few days of life are low and should ...
Rog-Zielinska Eva Alicia - - 2013
Glucocorticoids are steroid hormones, essential in mammals to prepare for life after birth. Blood levels of glucocorticoids (cortisol in most mammals including humans; corticosterone in rats and mice) rise dramatically shortly before birth. This is mimicked clinically in the routine administration of synthetic glucocorticoids to pregnant women threatened by a ...
O'Reilly Megan - - 2013
Background: Supplemental oxygen is necessary in the respiratory support of very preterm infants, but it may contribute to bronchopulmonary dysplasia and an increased risk of poor lung function in later life. It is well established that hyperoxia can inhibit alveolarization, but effects on the developing conducting airways, which are important ...
Loo Evelyn X L - - 2013
Background: Healthy gut microflora is essential for oral tolerance and immunity. A promising approach to preventing allergic diseases in genetically at-risk infants is to introduce administration of probiotics early in life when their immune system is still relatively immature. Objective: In this follow-up study, we aim to determine if early-life ...
Sonnenberg Amnon - - 2013
To test the long-term time trends of mortality from inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), for the presence of birth-cohort phenomena. We analyzed mortality data from the national statistical offices of Canada, England and Wales, Italy, the Netherlands, Switzerland, and the USA for the ...
- - 2013
An increasing number of deaths are preceded by end-of-life decisions liable to provoke or hasten death.
Lobo M A - - 2013
The purpose of this study was to determine the effectiveness of the Bayley Scales of Infant Development, Third Edition (Bayley-III) to track development and classify delays in low- and high-risk infants across the first two years of life. We assessed cognitive, language, and motor development in 24 low-risk full-term and ...
Koul Roshan - - 2013
A five month old infant is reported with Eating Epilepsy (feeding epilepsy/feeding related epilepsy). This is an uncommon type of reflex epilepsy in children, and should be considered if the history and investigations for gastro esophageal reflux and apparent life threatening event are negative. A clear stepwise history helps in ...
Turco Rossella - - 2013
This multicenter prospective study sought to establish possible risk factors for Functional Constipation (FC) in the first year of life. At the infant's age of 3, 6 and 12 months, parents of all included infants complete two questionnaires: one about the presence of FC and the second screened the possible ...
Wyckoff Myra H - - 2013
Chest compressions are rarely needed in newly born infants with an estimated occurrence of 0.08% for near-term and term deliveries; however, the consequences of a hypoperfused state on the brain and other organ systems can be devastating(1). Newborns that require prolonged cardiac compressions with no signs of life beyond 10 ...
Brandone Amanda C - - 2013
The ability to interpret and predict the actions of others is crucial to social interaction and to social, cognitive, and linguistic development. The current study provided a strong test of this predictive ability by assessing (1) whether infants are capable of prospectively processing actions that fail to achieve their intended ...
Pandey Ragini - - 2013
Diastolic dysfunction is common in infants and neonates with left ventricular (LV) outflow tract obstruction and may lead to low-cardiac output in the postoperative period. We present a management strategy for severe postrepair diastolic dysfunction in an infant with critical congenital aortic stenosis and LV hypertrophy, employing β-blockade and levosimendan.
Barros Marina Carvalho de Moraes MC Division of Neonatal Medicine, Department of Pediatrics, Universidade Federal de São Paulo - Escola Paulista de Medicina (UNIFESP-EPM), São PauloSP, - - 2013
Objective: To compare the neurobehavior of neonates born to adolescent mothers with and without depression during gestation. Methods: This prospective cross-sectional study included healthy term neonates born to adolescent mothers with untreated depression during gestation, without exposure to legal or illicit drugs, and compared them with infants born to adolescent ...
Gökçe Selim S Department of Pediatric Gastroenterology, Dr. Sami Ulus Maternity and Children's Health and Diseases Training and Research Hospital, Babür Caddesi, No:40, 06080, Altındağ/ Ankara, - - 2013
Background/aims:To determine the underlying causes and short-term prognosis of patients with conjugated hyperbilirubinemia in a tertiary neonatal intensive care units. Materials and Methods: We retrospectively analyzed the etiology, course, and shortterm prognosis of conjugated hyperbilirubinemia observed in newborn infants in a tertiary neonatal intensive care units. Results: Of a total ...
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