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Shelley E B EB Public Health Department,Health Service - - 2014
SUMMARY We describe two cases of infant botulism due to Clostridium butyricum producing botulinum type E neurotoxin (BoNT/E) and a previously unreported environmental source. The infants presented at age 11 days with poor feeding and lethargy, hypotonia, dilated pupils and absent reflexes. Faecal samples were positive for C. butyricum BoNT/E. ...
Haham Alon A 1 Department of Neonatology, Tel Aviv Medical Center, Tel Aviv, Israel, affiliated with Sackler Faculty of Medicine, Tel Aviv University , Tel Aviv, Israel - - 2014
Abstract Objective: The prevalence of a lingual frenulum in newborn infants is reportedly 0.3-12%. The purpose of this study was to describe the prevalence of a lingual frenulum based on the Coryllos classification in nonselected newborn infants after delivery, hypothesizing that it is higher than the values reported in the ...
La Rosa Patricio S PS Departments of Medicine - - 2014
In the weeks after birth, the gut acquires a nascent microbiome, and starts its transition to bacterial population equilibrium. This early-in-life microbial population quite likely influences later-in-life host biology. However, we know little about the governance of community development: does the gut serve as a passive incubator where the first ...
Raineki Charlis C Department of Cellular and Physiological Sciences, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC, Canada, V6T 1Z3. - - 2014
As one of the first rodent models designed to investigate the effects of early-life experiences, the neonatal handling paradigm has helped us better understand how subtle changes in the infant environment can powerfully drive neurodevelopment of the immature brain in typical or atypical trajectories. Here, we review data from more ...
Rupa Vedantam V Department of ENT, Christian Medical College, Vellore, India. Electronic address: - - 2014
Streptococcus pneumoniae is a leading cause of invasive disease in developing countries like India. Although the 13 valent pneumococcal vaccine has already been introduced in the country, there is very little epidemiological data regarding S. pneumoniae colonization and antibiotic susceptibility in Indian infants. We studied serogroup/serotype (SGT) distribution and antibiotic ...
Sletner Line L Department of Child and Adolescents Medicine, Akershus University Hospital, Lørenskog, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Norwegian Resource Centre for Women's Health, Oslo University Hospital, Oslo, - - 2014
Size and body composition at birth may affect long-term health. Mean birthweight and body composition differ between ethnic groups living in Europe. We wanted to explore if this relates to differences in socio-economic conditions in country of origin and over the maternal life course. This is a population-based cohort study ...
Huang Ke - - 2014
Permanent neonatal diabetes mellitus (PNDM) is a rare disease, which is defined as the onset of diabetes before the age of 6 months with persistence through life. Infants with KCNJ11 or ABCC8 genetic mutations may respond to oral sulfonylurea therapy. Currently, there are limited studies about the genetic analysis and ...
Khandaker Gulam G Centre for Perinatal Infection Research, The Children's Hospital at Westmead, Cnr Hawkesbury Rd and Hainsworth St, Locked Bag 4001, Westmead, NSW 2145, Australia. - - 2014
Background: This study examines national childhood HSV mortality data in Australia from1999-2011. This information is important to better understand the disease burden of HSV in early life and to formulate public health interventions. Methods: Retrospective analysis of Australian Bureau of Statistics (ABS) national mortality data from 1999-2011 in children aged ...
Panitch Howard B HB Division of Pulmonary Medicine, The Children's Hospital of Philadelphia, Philadelphia, - - 2014
Infants with congenital diaphragmatic hernia (CDH) have variable degrees of pulmonary hypoplasia at birth. Few reports of lung function over the first years of life exist in this group of children. Pulmonary function abnormalities correlate with severity of neonatal disease and intensity of neonatal therapies needed. We also hypothesized that ...
Lain Samantha J SJ Clinical and Population Perinatal Health Research, Kolling Institute of Medical Research, University of Sydney, Sydney, NSW, Australia. - - 2014
Objective: To examine the trends in hospital readmissions in the first year of life and identify whether changes in maternal and infant risk factors explain any changes. Design: Population-based study using de-identified linked health data. Participants: All 788 798 live-born infants delivered in New South Wales from 1 January 2001 to ...
Korppi Matti M Tampere Centre for Child Health Research, Tampere University and University Hospital, Tampere, - - 2014
Bronchiolitis is a viral lower respiratory tract infection characterised by inflammation and obstruction of the small airways. Respiratory syncytial virus (RSV) is the most common causative agent, followed by parainfluenza viruses, adenoviruses and the recently discovered metapneumovirus. Birth cohort studies have reported that the incidence of bronchiolitis is 18-32% during ...
Ekwunife O H OH Department of Surgery, Paediatric Surgery Unit, Nnamdi Azikiwe University Teaching Hospital, Nnewi, - - 2014
Background: Prune belly syndrome (PBS) is a rare congenital malformation of unclear etiology. The disease progress and outcome in developing countries are not clear as most reports are isolated case reports. Materials and Methods: A review of 9 patients managed for PBS in 5 years. Results: There were 7 males ...
Joarder Taufique T James P Grant School of Public Health, BRAC Institute of Global Health, BRAC University, 5th Floor (Level - 6), icddd,b Building, 68 Shahid Tajuddin Ahmed Sharani, Mohakhali, Dhaka, 1212, Bangladesh, - - 2014
The aim of this qualitative study was to explore the perceptions of meaning of death among the elderly in a Bangladeshi community, and to understand how the meaning of death affects one's overall well-being. Understandings of death were explored through the explanations respondents provided on the journey of the soul ...
Almgren Malin M Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; The Center for Molecular Medicine, Stockholm, - - 2014
Cesarean section (CS) has been associated with a greater risk for asthma, diabetes, and cancer later in life. Although elective CS continues to rise, it is unclear whether and how it may contribute to compromised future health. Our aim was to investigate the influence of mode of delivery on the ...
Dani Carlo C Department of Neurosciences, Psychology, Drug Research and Children's Health, University of Florence, Italy - - 2014
Background: Feeding intolerance is very frequent in preterm infants, and the development of an early effective biomarker for its prediction could be useful for carrying out a proper feeding strategy. Our aim was to evaluate if the measurement of splanchnic regional oxygenation (rSO2S) and splanchnic fractional oxygen extraction ratio (FOES) ...
Finn Daragh D Department of Paediatrics and Child Health, Neonatal Intensive Care Unit, University College Cork, Cork, Ireland, - - 2014
Modes of neonatal dying vary among maternity centres, both within and between countries. There have been few reports concerning mode of dying from countries with low rates of termination of pregnancy, such as Ireland. We conducted a retrospective chart review of all neonatal deaths, between January 2010 and January 2013, ...
Ulrich Timothy J B TJ Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, - - 2014
Automated monitoring of the QT interval is increasingly common in a variety of clinical settings. A better understanding of how the heart-rate-corrected QT interval (QTc) evolves in early postnatal life is needed before its clinical utility in neonates can be determined. This study aimed to use real-time bedside monitoring as ...
Vallès Yvonne Y Unidad Mixta de Investigación en Genómica y Salud, Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)-Salud Pública/Institut Cavanilles de Biodiversitat i Biologia Evolutiva (Universitat de València), València, - - 2014
In spite of its major impact on life-long health, the process of microbial succession in the gut of infants remains poorly understood. Here, we analyze the patterns of taxonomic and functional change in the gut microbiota during the first year of life for a birth cohort of 13 infants. We ...
Fike Candice D CD Dept. of Pediatrics, Vanderbilt University Medical Center, Nashville, TN; Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, - - 2014
Effective therapies are urgently needed for infants with forms of pulmonary hypertension that develop or persist beyond the first week of life. The L-arginine nitric oxide (NO) precursor, L-citrulline, improves NO signalling and ameliorates pulmonary hypertension in newborn animals. In vitro studies demonstrate that manipulating L-citrulline transport alters NO production. ...
Dahl Audun - - 2014
Emotional vocal signals are important ways of communicating norms to young infants. The second year is a period of increase in various forms of child transgressions, but also a period when infants have limited linguistic abilities. Two studies investigated the hypothesis that mothers respond with different vocal emotional tones to ...
Anderson Ariana A University of California, Los Angeles, 760 Westwood Plaza, CHS Suite B8-169, Los Angeles, CA 90095, USA. Electronic address: - - 2014
The recent Deoni et al. (2013) manuscript proposed that breastfeeding was associated with increased cognitive ability and white-matter in older children (over 26months), using ms-DESPOT MRI imaging to indirectly measure white matter in children who were either breastfed, formula fed, or combined breast+formula fed. In this response, we identify limitations ...
De Cunto Angela A Division of Neonatology, Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, - - 2014
We read with interest the paper by Olhager on body composition in late preterm infants (1). We wondered why the authors focused mainly on the first 10 days of life, stating that "on day four, most late preterm infants have adapted to extrauterine life": Micheli, quoted in the paper, reports ...
Block Walter E WE Loyola University New Orleans, New Orleans, Louisiana, - - 2014
There is a new sheriff in town on the abortion question. It is called evictionism. It diverges, philosophically, from both the pro-life and the pro-choice positions. It assumes that the birth of a human being starts with the fertilized egg but claims that the unwanted baby is a trespasser that ...
Smallenburg L C S LC Department of Pediatrics, Groene Hart Ziekenhuis, 2803 HH, Gouda, The Netherlands, - - 2014
Maternal pertussis-specific antibodies are passively acquired by infants during pregnancy. An IgG pertussis toxin (IgG-PT) concentration of >20 U/ml is considered to protect neonates against pertussis. To evaluate the IgG concentration at birth and during the first two months of life, we examined the IgG-PT concentration in the umbilical cord ...
Chen Zhu Z Center on the Early Life Origins of Disease, Department of Population, Family and Reproductive Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, - - 2014
There is an emerging hypothesis that exposure to cadmium (Cd), mercury (Hg), lead (Pb), and selenium (Se) in utero and early childhood could have long-term health consequences. However, there are sparse data on early life exposures to these elements in US populations, particularly in urban minority samples. This study measured ...
Proietti Elena E Inselspital and University of Bern, Bern, - - 2014
Compared with term-born infants, preterm infants have increased respiratory morbidity in the first year of life. We investigated whether lung function tests performed near term predict subsequent respiratory morbidity during the first year of life and compared this to standard clinical parameters in preterms.The prospective birth cohort included randomly selected ...
Armentrout Debra D University of Texas Medical Branch School of Nursing, Galveston, - - 2014
Successful transition from intrauterine to extrauterine life involves significant physiologic changes. The majority of these changes occur relatively quickly during those first moments following delivery; however, transition for the extremely preterm infant occurs over a longer period of time. Careful assessment and perceptive interventions on the part of neonatal care ...
Sarohia Mia - - 2014
Apparent life-threatening events account for 0.6% to 0.8% of all emergency department visits for children aged < 1 year. Risk factors for serious underlying pathology in a well-appearing infant have been identified as prematurity, underlying medical conditions, age < 60 days (considered controversial), suspicion of child abuse, possible seizure activity, ...
Koc F F Department of Social Pediatrics Ege University Medical School, Izmir, Turkey - - - 2014
The aim of the present study was to determine the prevalence of vitamin D supplementation and risk factors for non-supplemented infants in Izmir, Turkey. This cross-sectional study was carried out in Well-Child Care Clinics in Izmir, Turkey. Parents filled a questionnaire about socio-demographic characteristics and the use of vitamin D. ...
Paul Siba Prosad - - 2014
Vomiting is a common presentation in infants and is mostly due to a benign cause. Although vomiting is usually considered to be gastrointestinal in origin, it can be due to dysfunction of other organ systems, some of which may be life threatening. Community practitioners are often the first health professionals ...
Sierra Carlos C Hospital Materno-Infantil, Avda. Arroyo de los Ángeles s/n, 29011, Málaga, - - 2014
Currently, there is no consensus concerning the possible beneficial colonic and systemic effects of prebiotic-containing infant formula. This study assesses whether the feeding of a galactooligosaccharides (GOS)-containing infant formula (0.44 g/dl of GOS) and the subsequent feeding of a GOS-containing follow-on formula (0.50 g/dl of GOS) have a prebiotic effect on intestinal ...
Hasenstab Kathryn A KA The Neonatal and Infant Feeding Disorders Program, Center for Perinatal Research, Nationwide Children's Hospital Research Institute, Columbus, - - 2014
To test the hypothesis that proximal aerodigestive clearance mechanisms mediated by pharyngoesophageal motility during spontaneous respiratory events (SREs) are distinct in infants with apparent life threatening events (ALTEs). Twenty infants (10 with proven ALTE, 10 healthy controls) had pharyngoesophageal manometry to investigate motility changes concurrent with respiratory events detected by ...
Parravicini E E Division of Neonatology, Department of Pediatrics, Morgan Stanley Children's Hospital of NewYork-Presbyterian, Columbia University Medical Center, New York, NY, - - 2014
Objective:To describe the neonatal outcomes of a case series of infants who were prenatally diagnosed with potential life-limiting conditions and to whom individualized comfort measures were offered.Study Design:This is a retrospective analysis of the postnatal outcomes of a selected population of 49 infants prenatally diagnosed with potential life-limiting conditions whose ...
Yap Gaik Chin - - 2014
Studies have suggested that selective microbial targets prevail in the fecal microbiota of infants with eczema. This study evaluated the composition of fecal microbiota of infants who developed eczema in the first 5 years of life and compared these with those of healthy controls. Children who developed eczema in the ...
Ogden Thomas H TH 306 Laurel Street, San Francisco, CA, 94118, USA. - - 2014
Winnicott's Fear of breakdown is an unfinished work that requires that the reader be not only a reader, but also a writer of this work which often gestures toward meaning as opposed to presenting fully developed ideas. The author's understanding of the often confusing, sometimes opaque, argument of Winnicott's paper ...
Rais-Bahrami Khodayar K Department of Neonatology, Children's National Medical Center, The George Washington University School of Medicine, 111 Michigan Ave, NW, Washington, DC 20010. Electronic address: - - 2014
Extracorporeal membrane oxygenation (ECMO) continues to be an important rescue therapy for newborns with a variety of causes of cardio-respiratory failure unresponsive to high-frequency ventilation, surfactant replacement, and inhaled nitric oxide. There are approximately 800 neonatal respiratory ECMO cases reported annually to the Extracorporeal Life Support Organization; venoarterial ECMO has ...
Mesher Andrew L AL Department of Surgery, University of Washington School of Medicine, Seattle, - - 2014
Extracorporeal life support is an important therapy for neonates with life-threatening cardiopulmonary failure. Utilization of extracorporeal life support in neonates with congenital heart disease has increased dramatically during the past three decades. Despite increased usage, overall survival in these patients has changed very little and extracorporeal life support-related morbidity, including ...
Del Vecchio Antonio A Division of Neonatology, Neonatal Intensive Care Unit, Di Venere Hospital, Bari, Italy. Electronic address: - - 2014
Neonatal sepsis is frequently accompanied by significant and sometimes life-threatening coagulopathy. More complete understanding is needed of the molecular and cellular mechanisms underlying the interaction of the inflammatory and hemostatic systems. Such information may help focus future studies toward novel ways to improve the outcome of neonates who develop septic ...
Bilas Vlatka - - 2014
The main aim of this article is to explore determinants of life expectancy at birth among 28 European Union countries. Selected variables namely, gross domestic product (GDP) growth rate, population growth rate, level of education attained, education enrolment, GDP per capita and life expectancy have been considered for abovementioned countries ...
Milankov Olgica - - 2014
Piebaldism is an autosomal dominant disorder characterized by the congenital absence of melanocytes in the affected areas of skin and hair due to mutations of the KIT protooncogene, which affects the differentiation and migration of melanoblasts. A 3 1/2 month old male infant was admitted to hospital due to depigmentation ...
Kawamata Ryou - - 2014
Abstract Aim: To investigate changes of gut hormones in term and preterm infants in the first 2 months after birth, as the role and relationships of gut hormones in premature infants has not been well elucidated. Methods: In 29 preterm and five term infants, fasting serum concentrations of leptin, glucose-dependent ...
Chong Neto H J HJ Division of Pediatric Allergy and Immunology, Hospital de Clínicas, Federal University of Paraná, Curitiba, - - 2014
There are few published studies on prevalence of allergic rhinitis in preschool children. The aims of this study were to verify the prevalence, clinical characteristics, and treatment of allergic rhinitis (AR) symptoms in the first year of life adding supplementary questions to the EISL instrument. A cross-sectional study used Phase ...
Berglund Staffan S Department of Clinical Sciences, Pediatrics, Umeå University, Umeå, - - 2014
Iron deficiency early in life is associated with impaired neurological development. This study reviews the latest research on how to best meet iron requirements in infants and children. There is concurrent evidence that delayed cord clamping is well tolerated and improves infant iron stores. Iron supplements or enriched complementary foods ...
Farchi Sara - - 2014
The fetal and infant life are periods of rapid development, characterized by high susceptibility to exposures. Birth cohorts provide unique opportunities to study early-life exposures in association with child development and health, as well as, with longer follow-up, the early life origin of adult diseases. Piccolipiu is an Italian birth ...
Lorenz John M JM aDivision of Neonatology, College of Physicians and Surgeons, Columbia University bDivision of Pediatric Critical Care Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, - - 2014
To review the evolving management of infants/children with trisomy 18, the prognosis with and without medical intervention, the factors that have contributed to the evolving management strategies, and an approach to the formulation of healthcare management plans for newborns with trisomy 18. There has been a trend from nonintervention for ...
van Vonderen Jeroen J JJ Division of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, The - - 2014
The transition to life after birth is characterized by major physiological changes in respiratory and hemodynamic function, which are predominantly initiated by breathing at birth and clamping of the umbilical cord. Lung aeration leads to the establishment of functional residual capacity, allowing pulmonary gas exchange to commence. This triggers a ...
Short Scott S SS Division of Pediatric Surgery, Children's Hospital Los Angeles, and the Department of Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA; Division of Pediatric Surgery, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, - - 2014
The effect of timing of onset of necrotizing enterocolitis (NEC) on outcomes has not been determined for the full-term infant. In this study we aimed to characterize the full-term NEC population and to evaluate onset of NEC. We performed a two-center retrospective review of all full-term infants (≥ 37weeks) with ...
Charlton Jennifer R JR Department of Pediatrics, Division of Nephrology, University of Virginia, Box 800386, Charlottesville, VA, 22908, USA, - - 2014
Although there is wide variation, humans possess on average 900,000 nephrons per kidney. So far as is known, nephrons cannot regenerate; therefore, an individual's nephron endowment has profound implications in determining his or her long-term risk of developing chronic kidney disease. Most of the variability in human nephron number is ...
Reisner Gavriel G 55 West End Ave., #S15I, New York, NY 10023. E-mail: - - 2014
This article presents a revisionary reading of Freud's Beyond the Pleasure Principle. Recognizing the power of Freud's meditation on a universal "death-drive" in living organisms, it argues that Freud makes a greater contribution by strengthening the compulsion to repeat to a form of figurative death. We recall that after shattering ...
Wertheim David D Faculty of Science, Engineering and Computing, Kingston University, - - 2014
Non-invasive monitoring of breathing is a holy grail in paediatric respiratory, neonatal and sleep medicine. Respiratory rate is a key marker for the surveillance of sick infants and children (1-3), while repeated infant apnoeic episodes are associated with an increased risk of apparent life-threatening events (4). In clinical pulse oximetry, ...
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