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Results 51 - 100 of 1645
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Lulic-Botica Mirjana - - 2013
We compared gentamicin pharmacokinetics among neonates born small-for-gestational age (SGA) and appropriate for gestational age (AGA). We further compared gentamicin pharmacokinetics in subgroups of AGA and SGA neonates born preterm and term and treated within and after the initial week of age. Steady state peak and trough serum gentamicin concentrations ...
Medoff Marshall - - 2013
In the United States, pro-choice supporters contend that the desire of pro-life supporters to protect the life of the fetus ends at birth and that thereafter they ignore the health and well-being of infants and children. This study examines the question of whether infants and children fare better in U.S. ...
Taniuchi Mami M Division of Infectious Diseases and International Health, Department of - - 2013
Diarrhea causes enormous morbidity and mortality in developing countries, yet the relative importance of multiple potential enteropathogens has been difficult to ascertain. We performed a longitudinal cohort study from birth to 1 year of age in 147 infants in Dhaka, Bangladesh. Using multiplex polymerase chain reaction, we analyzed 420 episodes ...
Al-Maawali Almundher A - - 2013
Infants with phosphomannomutase 2 - congenital disorder of glycosylation (PMM2-CDG), formerly known as CDG1a, present with failure to thrive, visceral dysfunction, thromboembolic events and developmental delays noted before 6 months of age. Diagnosis is often delayed due to the considerable variability in phenotype. Characteristic, but not universal, features include inverted nipples ...
McLeod-Sordjan Renee - - 2013
To report analysis of the concept death preparedness in the context of end-of-life shared decisions and communication. Forty percent of older people require decision-making and communication in the final days of life. Elaborate defence mechanisms have yielded a public consciousness that no longer passively views death acceptance, but instead has ...
Dani Carlo - - 2013
The relationship between cord arterial pH (CA-pH) >7.000 and the neonatal outcome is not clear. To evaluate if asymptomatic infants born with unexpected cord arterial pH (CA-pH) between 7.000 and 7.100 develop clinical, biochemical, and instrumental signs of hypoxic cerebral, renal, and heart failure more frequently than symptomatic infants. Term ...
Bornstein Marc H MH Child and Family Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Public Health Service, Bethesda, Maryland 20892; email: - - 2014
Human infancy has been studied as a platform for hypothesis and theory testing, as a major physiological and psychological adjustment, as an object of adults' effects as well as a source of effects on adults, for its comparative value, as a stage of life, and as a setting point for ...
Din Osmun Laila - - 2013
Objectives To examine the predictive relationships of early infant and caregiver variables on expressed pain-related negative affect duration at the 12-month immunization. Infants and their caregivers (N = 255) were followed during immunization appointments over the first year of life. Latent growth curve modeling in a structural equation modeling context ...
Prosser Amy - - 2013
Background:Deficiencies in phagocytosis may contribute to the increased susceptibility of infants to early life infections. Data on phagocytosis of the major neonatal pathogens Staphylococcus epidermidis (SE), Staphylococcus aureus (SA) and Escherichia coli (EC) by preterm infant leucocytes are inconsistent.Methods:Cord and <24h peripheral blood were collected from very preterm (<30.1 weeks ...
Prosser Amy - - 2013
Background:Deficiencies in phagocytosis may contribute to the increased susceptibility of infants to early life infections. Data on phagocytosis of the major neonatal pathogens Staphylococcus epidermidis (SE), Staphylococcus aureus (SA) and Escherichia coli (EC) by preterm infant leucocytes are inconsistent.Methods:Cord and <24h peripheral blood were collected from very preterm (<30.1 weeks ...
Douglas Pamela S - - 2013
The United Kingdom's National Institute for Health Research has recently invited proposals for the design of a multicomponent primary care package of behavioral interventions to reduce parental distress caused by excessive infant crying in the first 6 months of life. A systematic review was performed to determine whether behavioral interventions ...
Callaghan M - - 2013
Extra corporeal membrane oxygenation (ECMO) is a form of life support, which facilitates gas exchange outside the body via an oxygenator and a centrifugal pumping system. A paediatric cardiac ECMO programme was established in 2005 at Our Lady's Children's Hospital, Crumlin (OLCHC) and to date 75 patients have received ECMO, ...
Southgate Victoria - - 2013
It is well established that, from an early age, human infants interpret the movements of others as actions directed towards goals. However, the cognitive and neural mechanisms which underlie this ability are hotly debated. The current study was designed to identify brain regions involved in the representation of others' goals ...
Mirochnick Mark - - 2013
Data describing the pharmacokinetics and safety of tenofovir in neonates are lacking. HPTN 057 was a phase 1, open label study of the pharmacokinetics and safety of tenofovir disoproxil fumarate (TDF) in HIV infected women during labor and their infants during the first week of life with 4 dosing cohorts: ...
Dórea José G - - 2013
This review explores the different aspects of constitutional factors in early life that modulate toxicokinetics and toxicodynamics of low-dose mercury resulting from acute ethylmercury (etHg) exposure in Thimerosal-containing vaccines (TCV). Major databases were searched for human and experimental studies that addressed issues related to early life exposure to TCV. It ...
Telzer Eva H EH Department of Psychology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA. - - 2013
In the current study, we investigated how complete infant deprivation to out-group race impacts behavioral and neural sensitivity to race. Although monkey models have successfully achieved complete face deprivation in early life, this is typically impossible in human studies. We overcame this barrier by examining youths with exclusively homogenous racial ...
de Weerth Carolina - - 2013
Up to around a quarter of all infants cry excessively and unsoothably during their first months of life. This phenomenon has been termed "infant colic." In most cases, physicians are unable to determine the cause of the colicky behavior. In a recent study, and by means of comprehensive and deep ...
Duerden Emma G - - 2013
Intensive resuscitation at birth has been linked to intraventricular haemorrhage (IVH) in the preterm neonate. However, the impact of less intensive resuscitation on more subtle alterations in brain metabolic development is largely unknown. Our objective was to determine the relationship between the intensity of neonatal resuscitation following preterm birth on ...
Romagnoli Costantino - - 2013
Transcutaneous bilirubinometry is widely used to predict hyperbilirubinemia by using several devices. The aim of this study was to compare the predictive ability of BiliCheck vs JM-103 in identifying neonates not at risk of significant hyperbilirubinemia, putting the data obtained with the two instruments on our transcutaneous bilirubin nomogram built ...
Kinney Hannah C - - 2013
Witnessed reports of sudden death are rare, but critical to deciphering its mechanism(s). We report such a death in a seemingly healthy 8-month-old boy in whom seizures and respiratory distress in the prone position were witnessed upon discovery during a sleep period. Following cardiopulmonary resuscitation, anoxic encephalopathy resulted in "brain ...
Oozeer Raish - - 2013
Human milk is generally accepted as the best nutrition for newborns and has been shown to support the optimal growth and development of infants. On the basis of scientific insights from human-milk research, a specific mixture of nondigestible oligosaccharides has been developed, with the aim to improve the intestinal microbiota ...
Yapakçı Ece - - 2013
Background: This study aimed to examine the differences between arterial and inferior caval vein oxygen saturation, fractional oxygen extraction, and the shunt index, which were calculated in the diagnosis of patent ductus arteriosus. Methods: Twenty-seven preterm infants were included in this study and were divided into two groups according to ...
Ray Kristin N - - 2013
The goal of this study was to describe hospitalizations of infants during the first year of life according to week of gestational age (GA). We hypothesized that odds of any hospitalization would generally decrease with increasing GA, with late preterm infants experiencing additional increased risk of specific hospitalizations, such as ...
Said Habib Hamed H Dr.amed Said HabibDean, Rabigh College of Medicine, Associate Professor and Consultant of Pediatrics, Pediatric Department, Faculty of Medicine, King Abdulaziz University, Saudi - - 2013
Background: Transition from a parallel circulation in utero to an in-series circulation immediately after birth is partly an oxygen-dependent process. Relative hypoxemia with increasing altitude above sea level exerts a certain degree of stress on oxygen-dependent metabolic processes throughout the body. Objective: The present study aimed to determine the reference ...
Rath M E A - - 2013
Ferritin levels are often highly elevated at birth in neonates with alloimmune haemolytic disease of the fetus and newborn (HDFN). Data on ferritin levels in these infants in the first 3 months of life are lacking. Objective of this study was to examine the course of iron status and incidence of ...
Lehtonen Eveliina - - 2013
To examine the use of vitamin D supplements during infancy among the participants in an international infant feeding trial. Longitudinal study. Information about vitamin D supplementation was collected through a validated FFQ at the age of 2 weeks and monthly between the ages of 1 month and 6 months. Infants ...
Georgi Gilda - - 2013
Human milk contains complex carbohydrates that are important dietary factors with multiple functions during early life. Several aspects of these glycostructures are human specific; some aspects vary between lactating women, and some change during the course of lactation. This review outlines how variability of complex glycostructures present in human milk ...
Guimarães Elaine Leonezi - - 2013
The aims of this systematic literature review were to examine and discuss studies that investigated reaching in preterm infants during the first year of life. Databases were searched using keywords such as "reaching," "grasping", "preterm" and "premature", in addition to specific terms from the Medical Subject Headings (MeSH): "motor skills", ...
Pickles Andrew - - 2013
BACKGROUND: The low expression polymorphism of the MAOA gene in interaction with adverse environments (G × E) is associated with antisocial behaviour disorders. These have their origins in early life, but it is not known whether MAOA G × E occurs in infants. We therefore examined whether MAOA G × ...
Vasudevan Chakrapani - - 2013
Neonatal seizures constitute the most frequent and distinctive neurological symptom in the neonatal period. Seizures in the neonatal period differ considerably from those observed later in life with respect to their aetiological profile and clinical presentation. In addition, the aetiological profile in preterm infants is different from that seen in ...
Kapadia Vishal S - - 2013
OBJECTIVE: To determine whether early hyperoxemia in neonates with severe perinatal acidemia is associated with the development of hypoxic-ischemic encephalopathy (HIE). STUDY DESIGN: We identified 120 infants at ≥36 weeks gestational age with perinatal acidosis born at Parkland Hospital who qualified for a screening neurologic exam for cooling therapy. Based ...
Williamson James R - - 2013
Apnea of prematurity is a common disorder of respiratory control among preterm infants, with potentially serious adverse consequences on infant development. We review the capability for automatically assessing apnea risk and predicting apnea episodes from multimodal physiological measurements, and for using this knowledge to provide timely therapeutic intervention. We also ...
Fonseca Ana - - 2013
The present study examined psychological adjustment in parents of infants with congenital anomalies (CAs), focusing on the interval from the disclosure of the diagnosis to six months after the infant's birth and considering the effects of the parent's gender and the timing of diagnosis (pre- vs postnatal). Within-group diversity was ...
Gezmish Oksan - - 2013
Vitamin D deficiency is a major worldwide public health problem affecting people of all ages, from infants to the elderly. Of particular concern is the high incidence of vitamin D deficiency in women during pregnancy and lactation, leading to the exposure of the growing fetus/infant to inadequate levels of vitamin ...
Sundaram Maria E - - 2013
Exclusive breastfeeding of newborns, a practice recommended by WHO, is hindered in many countries by practices such as prelacteal feeding (feeding other foods before breast milk is fed to infants). This paper describes maternal and infant characteristics and trends over time associated with early neonatal feeding (ENF) in Bangladesh. The ...
O'Sullivan Aifric - - 2013
Epidemiological research has indicated a relationship between infant formula feeding and increased risk of chronic diseases later in life including obesity, type-2 diabetes, and cardiovascular disease. The present study used an infant rhesus monkey model to compare the comprehensive metabolic implications of formula- and breast-feeding practices using NMR spectroscopy to ...
Preer Genevieve - - 2013
Abstract Background and Objective: Until 2010, newborns at our institution were bathed in the nursery at approximately 2 hours of life. In May 2010, infant baths were delayed until at least 12 hours of life. Infants are now bathed in the hospital room with parents' participation and are placed skin-to-skin ...
Knoepffler Nikolaus Johannes - - 2013
The basic human experience of the atrocities in the first half of the 20th century has significantly strengthened the recognition of human dignity and human rights for all born people at the political level. Therefore, the Charter of the United Nations in 1945 and its Universal Declaration of Human Rights ...
Goldman Ran D - - 2013
Question As a family physician who frequently attends deliveries and follows up with neonates, parents often ask me if they can provide their newborns with pacifiers in order to calm infants down, reduce crying, and improve sleep. Is pacifier use safe in the first month of life? Answer While pacifiers ...
Kassar Samir B - - 2013
OBJECTIVE: To identify risk factors for neonatal mortality, focusing on factors related to assistance care during the prenatal period, childbirth, and maternal reproductive history. METHODS: This was a case-control study conducted in Maceió, Northeastern Brazil. The sample consisted of 136 cases and 272 controls selected from official Brazilian databases. The ...
Chapman Derek A - - 2013
This paper examined the generational recurrence of low birthweight (LBW) among first-born singletons using a statewide maternally-linked birth dataset. An intergenerational dataset was created by linking 2005-2009 to 1960-1997 Virginia resident live birth data. Maternal information from the recent birth cohort was linked to infant information in the historic birth ...
Kanavaki Aikaterini - - 2013
The authors report a case of a preterm infant at 29 weeks of gestation who gradually developed a Chiari malformation Type I (CM-I) with hydrocephalus due to a premature unilateral fusion of the posterior intraoccipital synchondrosis. Brain ultrasonography results in the 1st week of life were normal. Follow-up ultrasonography showed ...
Johns Hm - - 2013
AIM: To examine in-hospital infant feeding practices, focusing on initiation and prevalence of breast milk expression and to describe the proportion of women having a breast pump immediately after birth. METHODS: Postpartum women were recruited from three hospitals in Melbourne, Australia between 2009 and 2011. Inclusion criteria: having had a ...
Jiang Xiaodong - - 2013
Cyanobacterial blooms are becoming potent agents of natural selection in aquatic ecosystems because of their high production of some toxins and increased frequency in recent decades with eutrophication and climate change. Maternal exposure to the toxic Microcystis aeruginosa significantly increased the intrinsic rates of population increase, average life span, and ...
Dargaville Peter A - - 2013
Background: Preterm infants ≤32 weeks' gestation are increasingly being managed on continuous positive airway pressure (CPAP), without prior intubation and surfactant therapy. Some infants treated in this way ultimately fail on CPAP and require intubation and ventilation. Objectives: To define the incidence, predictors and consequences of CPAP failure in preterm ...
Faas Ana Eugenia - - 2013
This study evaluated the neonatal responsiveness to the odor of amniotic fluid during the first hours of life. Twenty five newborn infants born by C-section at 36-40 weeks of gestation were evaluated with 1; 5 or 25 drops of amniotic fluid at 1 hour, 3.5 hours and 6 hours of ...
Mian Asma - - 2013
The 16th century French anatomist Guillaume Rondelet will be remembered as a great naturalist and a founder of ichthyology. Little known to most is that Rondelet was a proficient anatomist and contemporary to Vesalius and in fact, both studied anatomy under Johannes Guinter. Even less known is that he established ...
Albertine Kurt H KH Department of Pediatrics, University of Utah, School of Medicine, Salt Lake City, UT 84158-1289, USA. - - 2013
Bronchopulmonary dysplasia (BPD) is among the most common chronic lung diseases in infants in the US. Improved survival of preterm infants who developed BPD is becoming increasingly important because of the high risk for persistent pulmonary morbidities such as poor respiratory gas exchange, pulmonary hypertension, and excess airway expiratory resistance ...
Khajeh Ladbon - - 2013
Apneic neonatal seizures can present as apparent life-threatening events. We report a newborn with unexplained episodes of apnea associated with cyanosis and desaturation, starting on the first day postpartum. Biochemical tests were normal. Central nervous system infections as well as abnormalities of upper airways and cardiovascular system were excluded. Brain ...
Mastrangelo Massimo - - 2013
Early-onset epileptic encephalopathies (EOEEs) are characterised by epileptic seizures beginning in the first months of life, abnormal background EEG activity, and are associated with severe developmental delay and poor prognosis. Mutations and deletions in the STXBP1 gene are associated with Ohtahara syndrome, also known as "early infantile epileptic encephalopathy". We ...
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