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Results 601 - 650 of 789
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Jones G R - - 1987
Two normal appearing infants presented in the newborn period with elevated white blood cell counts and immature blast cells. Initial bone marrow karyotype analysis showed trisomy of chromosome 21 in all metaphases. In both patients blastemia spontaneously resolved and percentage of trisomy 21 cells decreased. One infant required multiple exchange ...
Ino T - - 1986
An infant who died at 5 months with hypertrophic cardiomyopathy accompanied by QT prolongation was examined at autopsy. At the age of 16 days, serum IgM level was elevated (226 mg/dl). Microscopic examination revealed characteristics of hypertrophic cardiomyopathy with myocardial cell hypertrophy with disarray and healed myocarditis with patchy fibrosis ...
Tovey L A - - 1986
Between 1950 and 1970 there was a steady decline in the number of infant deaths from rhesus haemolytic disease of the newborn in the Yorkshire Region but no decrease in the number of pregnant women with antibodies. Following the introduction of Rh prophylaxis in 1970, the number of pregnant women ...
Zochodne D - - 1986
An 8-month-old male infant with cystic fibrosis developed quadriplegia secondary to spinal cord compression. Surgery revealed an extensive intradural hematoma from C3 to T9. An underlying structural source of bleeding was not identified and the patient did not have a coagulopathy. Repeated chest physiotherapy was the only known trauma that ...
Floss A M - - 1986
We conducted studies of both red cell (RBC) and leukocyte (WBC) antibody formation in infants following multiple transfusions given during the first weeks of life. Fifty-three infants received 683 RBC transfusions from 503 different donors, plus 62 platelet, 4 granulocyte, and 53 fresh-frozen plasma units during the first 4 months ...
Murphy D J DJ - - 1986
Digitized M-mode echocardiography was used to evaluate left ventricular (LV) function in normal neonates and to document subtle abnormalities of LV function in 19 asymptomatic newborn infants with polycythemia and hyperviscosity. Echocardiograms were performed before and after partial exchange transfusion and at 48 hours of age. Results were compared to ...
Giacoia G P - - 1986
Severe transient hyperammonemia is a disorder of unknown etiology which can be successfully treated. This article describes two infants affected by this condition and reviews the pertinent literature. Forty-nine cases, including our own, are summarized. Large prematures (mean birthweight 2534 +/- 738 gm, gestational age 36.1 +/- 4.05 weeks) and ...
King A - - 1986
Meconium ileus and pancreatic changes, as described in cystic fibrosis, were found, at autopsy, in a series of six infants who received prolonged neonatal intensive care for prematurity. Cystic fibrosis had not been suspected clinically. These pathological findings are so frequent in sick premature infants, amounting to 12% of all ...
Yoder M C - - 1986
This chapter has reviewed the deficiencies in immune defense that place the neonate, particularly the premature infant, at increased risk of invasive bacterial disease. We also have reviewed the literature on the rationale for exchange transfusion, granulocyte transfusion, intravenous immunoglobulin, and fibronectin administration as immunotherapeutic agents in infected infants. There ...
Oh W - - 1986
The combination of polycythemia and hyperviscosity in the newborn is a common problem. The incidence will vary depending on the environment and population involved because factors such a high altitude and high-risk pregnancies will markedly influence the incidence of this complication. The timing of the cord clamping at birth in ...
Brabin B J - - 1986
To investigate folacin concentrations in malaria during pregnancy, women attending a rural antenatal clinic in Kenya were studied. Low serum folacin values had poor specificity for low red blood cell (RBC) folacin concentrations. Multigravidae had lower mean serum folacin (p less than 0.03) and RBC folacin (p less than 0.001) ...
Abman S H - - 1986
Young infants with cystic fibrosis (CF) are at risk for developing symptomatic protein-calorie malnutrition (PCM) characterized by hypoalbuminemia, edema, and anemia. We reviewed the hospital charts of all infants less than 12 months of age referred to our CF clinic between 1979 and 1982 and found nine patients with PCM ...
Gowen C W - - 1986
Patients with cystic fibrosis (CF) have an increased nasal transepithelial potential difference (PD) which reflects increased sodium absorption across epithelium relatively impermeable to chloride. To evaluate nasal epithelial function in neonates with CF, the PD was recorded and the voltage response to superfusion of 10(-5M) amiloride, an inhibitor of sodium ...
Bada H S - - 1986
Cerebral arterial pulsatile flow changes and the effect of partial plasma exchange transfusion on these pulsatile flow patterns were studied in neonatal polycythemia/hyperviscosity syndrome by transcutaneous Doppler technique. Twenty-two infants with cord blood hematocrit greater than 58% (greater than 2 SD above the mean) were studied from a total of ...
Ogala W N - - 1986
Normal values for haemoglobin concentration, packed cell volume, red blood cell counts and mean cell volume were serially electronically determined in a cohort of 99 healthy, normal fullterm Nigerian babies and infants from age 1 day-6 months. Mean values of haemoglobin concentration, packed cell volume and red blood cell counts ...
Tadolini B - - 1986
The polyamines associated to human erythrocytes from healthy donors are mainly localized intracellularly. In fact chromatography of the erythrocytes on a resin which has a high affinity and capacity for polyamines does not affect the amount of polyamines associated to the erythrocytes. The low ability of spermine to adsorb to ...
Mimouni F - - 1986
Two premature infants who had episodes of hemolysis following blood transfusion are described. No incompatibility was found between donor and infant in either case. Further investigation of the donors' blood excluded other possible causes of hemolysis. The only anomaly found was that the donors were glucose-6-phosphate dehydrogenase (G6PD) deficient, while ...
Stockman J A JA - - 1986
At no other time of life is the decision to transfuse potentially as difficult as in the newborn period. Superimposed upon complex "physiologic" changes in the ability to deliver and release oxygen are varying requirements among infants in terms of oxygen need. These are compounded by changes brought about as ...
Ostgård P - - 1986
An Rh positive woman having the Rh(D) variant designated DVI formed a potent anti-D which caused a severe haemolytic disease in the infant. The infant received three exchange transfusions within the first 21 hours after delivery and, because of a 'late anaemia', three additional blood transfusions during the first 3 ...
Wiley J F JF - - 1986
The purpose of this study is to compare a revised rule of thumb with the Harriet Lane and Behrman's formulas for predicting haematocrit rise following packed red blood cell (PRBC) transfusion in premature neonates. Pre- and post-transfusion, equilibrated central haematocrits were obtained within 24 h of transfusion in 12 premature ...
Linderkamp O - - 1986
Deformability of red blood cells (RBC) is an important determinant of microcirculation, of oxygen transport and release to the tissues, and of RBC life span. Deformability of RBC from five fetuses, 20 preterm infants, 20 term neonates, and 20 adults was determined by direct microscopic observation of RBC subjected to ...
Strauss R G - - 1986
Two controversial issues of neonatal transfusion practices, erythrocyte 'booster' transfusions and granulocyte transfusions, are critically reviewed, and current recommendations for transfusion practices are made. Infants should receive erythrocyte transfusions to treat congestive heart failure caused primarily by anemia. It is customary to maintain the hematocrit at greater than 40% in ...
Murphy D J DJ - - 1985
Although infants with neonatal polycythemia and hyperviscosity often present with cardiorespiratory distress, little information is available regarding the cardiac function of such babies before or after partial exchange transfusion. To assess cardiac function, we performed M-mode echocardiograms in 19 asymptomatic newborn infants (4 to 12 hours of age) who had ...
Pahwa S - - 1985
Methodology was established to analyze T lymphocytes and T cell subsets with monoclonal antibodies on microsamples of blood obtained by heel puncture in infants. Results in 39 high-risk infants indicated that during the early neonatal period they had a higher percentage of T4-bearing cells and a lower percentage of T8 ...
Sjöberg P - - 1985
The dispositions of the plasticizer di-(2-ethylhexyl) phthalate (DEHP) and its primary metabolite mono-(2-ethylhexyl) phthalate (MEHP) were studied in newborn infants subjected to exchange transfusions. During a single exchange transfusion the amounts of DEHP and MEHP infused ranged from 0.8-3.3 and 0.05-0.20 mg kg-1 body weight, respectively. There were indications that ...
Luban N L - - 1985
Essential to the management of the sick, low birth weight infant is maintenance of a neutral thermal environment by use of convection incubators and radiant warmers. Manipulation of the infant in preparation for transfusion and the transfusion of cold blood could theoretically lower the infant's body temperature, subsequently contribute to ...
Stegagno M - - 1985
The immunologic status and the occurrence of alloimmunization against granulocytes, platelets, lymphocytes, and red cells was evaluated in 33 babies who received granulocyte transfusion because of neonatal sepsis. Nine age-matched babies were examined as control. A first group of 19 infants was examined only once between 6 and 23 months ...
Koeslag J H - - 1985
Reproductive compensation may be prezygotic or postzygotic. Prezygotic compensation is the replacement of inviable infants by one or more additional births. When the marital fertility rates are greater than necessary to replace the parents, however, many traditional societies ensured that any surviving progeny in excess of two (on average) did ...
de Crespigny L C - - 1985
Four fetuses with severe rhesus isoimmunization were transfused with packed red blood cells directly into the umbilical vein. The outcome was successful in three. In one infant, this ultrasound-guided technique resulted in resolution of severe fetal hydrops at 27 weeks, allowing delivery of a healthy nonhydropic infant at 33 weeks, ...
Sjöberg P O - - 1985
The exposure of newborn infants to the plasticizer di-(2-ethylhexyl) phthalate (DEHP) and its primary metabolite mono-(2-ethylhexyl) phthalate (MEHP) was studied during exchange transfusions by measuring their contents in the infused blood. Plasma concentrations of DEHP and MEHP in the blood withdrawn from the infants during the transfusions also were determined. ...
Snyder J R - - 1985
A 7-year-old burro jack was examined because of recurrent rectal prolapse and severe cough. The prolapse was reduced manually and a cough associated with bronchopneumonia responded to antimicrobial therapy. The rectal prolapse recurred and again was reduced manually. During exploratory celiotomy a cystic calculus was identified and removed. Severe protracted ...
Scott-Emuakpor A B - - 1985
A longitudinal study of normal hematological values of the newborn infant was undertaken in an effort to provide baseline data for assessing the African Neonate with hematological problems. There were 402 neonates, consisting of 304 full-term, 51 preterm and 47 post-term infants. The Hematocrit (Hct), Hemoglobin (Hb), Red Blood Cell ...
Black V D - - 1985
The use of partial plasma exchange transfusion in newborns with polycythemia and hyperviscosity was evaluated. Ninety-three infants with polycythemia and hyperviscosity were randomly assigned to receive either partial plasma exchange transfusion or symptomatic treatment; the infants were matched with control infants without polycythemia. Neonatal course and outcome at 1 and ...
Wesley A W - - 1985
The incidence of and mortality from cystic fibrosis in New Zealand from 1960 to 1983, has been reviewed. Cystic fibrosis subjects have been located from data obtained from New Zealand paediatricians, the Cystic Fibrosis Association and hospital admission records. Mortality figures in the years 1960-1982 were also obtained. The incidence ...
Segal S - - 1985
Sudden infant death syndrome (SIDS) is a term applied to the sudden death of an infant that defies explanation. The infant apnea syndrome (formerly the near-miss for SIDS) has come to apply to a different population of infants who are unlikely to have died from SIDS. The use of monitoring ...
Hovi L - - 1985
1 069 newborns were subjected to exchange transfusion with fresh heparinized blood in the years 1968, 1971, 1974, 1977 and 1981. There were 258 infants with Rh disease, 328 with hyperbilirubinemia with ABO incompatibility, 436 with hyperbilirubinemia without ABO incompatibility and 47 infants without hyperbilirubinemia or evidence of hemolytic disease. ...
Irving C S - - 1985
The first bicarbonate pool sizes and kinetic data necessary for the interpretation of substrate oxidation studies have been determined in six fed, nonacidotic infants, ages 2.5 to 5 months. Following an intravenous bolus of NaH13CO3 (50 mumol/kg), breath samples were collected over 240 min for the analysis of breath 13CO2. ...
Thomas D - - 1985
Gastroesophageal reflux (GER) was initially diagnosed in two black infants, aged 5 and 9 months, as a cause of their chronic lung disease and failure to thrive. Both infants were treated with bethanechol chloride as part of the management of their GER, but respiratory failure developed in both patients and ...
Wiley J F - - 1985
Changes in serum potassium in premature neonates undergoing transfusion from CPDA-1 triple satellite PRBC paediatric packs cannot be predicted solely on the basis of potassium dose and estimated plasma volume. Despite significant potassium loading during PRBC transfusion, the actual serum potassium change is much less than predicted in neonates with ...
Brown M S - - 1985
We observed a temporary rise in the percentage of fetal hemoglobin (HbF%) in small preterm infants after cessation of frequent replacement transfusions. We prospectively studied 10 very low birthweight infants, who received frequent transfusions in the first several weeks of life, to determine the influence on oxygen affinity (P50). After ...
Travis S F - - 1985
Red cell glycolytic intermediates and ATP were evaluated in 47 appropriate for gestational age preterm infants on the 1st day of life who were divided into three groups on the basis of gestational age: 28-30, 31-33, and 34-36 wk. The results were compared to those previously obtained in term infants. ...
Nwaesei C G - - 1984
Auditory brainstem responses (ABR) were evoked, before and after exchange transfusion, in an effort to determine whether hyperbilirubinemia is associated with acute effects on brainstem function of neonates. Nine full-term infants with hemolytic disease received exchange transfusion for conventional serum bilirubin concentration indications (mean 22.3 +/- 1.4 mg/dL). In three ...
Oie B K - - 1984
A young woman with acquired chronic pure red cell aplasia (PRCA) gave birth to 3 infants with foetal hydrops. The 1st infant died shortly after birth, while the 2nd was stillborn with severe anaemia. Both had signs of increased erythropoiesis at autopsy. The 3rd infant was saved by foetal intrauterine ...
Church J A - - 1984
Two preterm infant boys not known to be at risk developed clinical, laboratory, and pathologic features of acquired immune deficiency syndrome (AIDS) after receiving multiple blood transfusions in the neonatal period. Their clinical courses were characterized by failure to thrive, recurrent otitis media, hepatomegaly, and fatal interstitial pneumonia. Laboratory evaluation ...
LeBlanc M H - - 1984
Although necrotizing enterocolitis has been associated with polycythemia in human infants, a causal relationship has not been established. Forty-six unanesthetized puppies were studied (age 6 to 14 days). Normovolemic polycythemia (Hct 0.70) was induced in 19 pups by exchange transfusion with 75 ml/kg packed red blood cells. Hypervolemic polycythemia (Hct ...
Rovamo L - - 1984
Postheparin plasma lipoprotein lipase and hepatic lipase activities of 11 preterm infants aged 1 to 4 days were measured 15 min after a heparin bolus of 100 IU/kg and during an exchange transfusion performed with fresh heparinized blood. Each infant had a birth weight (range, 1210-3490 g) appropriate for gestational ...
Franckx J - - 1984
Sweat osmolality determination with 7-10 microliter of sweat for the establishment of the diagnosis of cystic fibrosis (CF) was evaluated in 297 probands. In 12 out of 26 infants below 2 months of age and in 3 out of 271 older probands not enough sweat could be collected at the ...
Blank J P - - 1984
Fifty-six premature infants with a mean gestational age at birth of 30 weeks were randomly assigned to a transfusion group, for whom the hemoglobin level was kept above 10.0 g/dL, and a nontransfusion group, who were transfused only for specific clinical indications. The groups were followed up longitudinally with weekly ...
Osborn L M - - 1984
Current guidelines for treatment of hemolytic disease of the newborn make no differentiation between ABO and Rh incompatibility. A protocol that prolonged the observation period in full-term, ABO-incompatible infants with positive Coombs' tests who were otherwise healthy was tested. Postponement of treatment made it possible to determine more accurately which ...
Roberts I - - 1984
A case of paracetamol overdose in a 36 week pregnant woman is described. The baby was delivered by Caesarian section 6 h after the overdose. The mother but not the baby was treated with N-acetylcysteine and neither suffered liver damage. The plasma paracetamol half-life was prolonged to 10 h in ...
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