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Wainwright Helen H 1NHLS D7 Laboratory, Groote Schuur Hospital, Cape Town, South Africa 2Department of Anatomical Pathology, UCT Faculty of Health Sciences, Cape Town, South - - 2014
The lifesaving therapies and procedures used in the care of neonates may result in untoward effects and complications. Retinitis of prematurity (ROP) may present as a spectrum of disease ranging from spontaneously resolving vasculopathy to retinal detachment and blindness. Total parenteral nutrition (TPN) is found in 40-60% of infants requiring ...
Manzoni Paolo P Neonatology and NICU, S. Anna Hospital, Torino Italy. Electronic address: - - 2014
Retinopathy of prematurity (ROP) is a multifactorial disease with evidence of many associated risk factors. Erythropoietin has been reported to be associated with this disorder in a murine model, as well as in humans in some single-center reports. We reviewed the data from two large tertiary NICUs in Italy to ...
Chen Yi-Hsing YH *Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan; †College of Medicine, Chang Gung University, Taoyuan, Taiwan; ‡Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan; §Department of Ophthalmology, Mackay Memorial Hospital, Taipei, Taiwan; ¶Graduate Institute of Clinical Medical Science, Chang Gung University, Taoyuan, Taiwan; **Clinical Informatics and Medical Statistics Research Center, Chang Gung University, Taoyuan, Taiwan; and ††Biostatistical Center for Clinical Research, Chang Gung Memorial Hospital, Taoyuan, - - 2014
To investigate the 2-year outcomes of the natural history of retinopathy of prematurity (ROP) in Taiwan. A prospective study was conducted at two tertiary medical centers. Premature infants were screened and examined for ROP. The postmenstrual ages of developing each stage of ROP and the associated risk factors were recorded. ...
Asztalos Elizabeth - - 2014
The Multiple Courses of Antenatal Corticosteroids for Preterm Birth Study (MACS) showed no benefit in the reduction of major neonatal mortality/morbidity or neurodevelopment at 2 and 5 years of age. Using the data from the randomized controlled trial and its follow-up, the aim of this study was to evaluate the ...
Hussein Mohamed A MA Baylor College of Medicine and Texas Children's Hospital. Electronic address: - - 2014
To explore the association of autonomic agents with the development and severity of retinopathy of prematurity (ROP). The medical records of all preterm infants screened for ROP were retrospective reviewed. The association between development and severity of ROP and the use and dose(s) of autonomic agents was analyzed, after adjustment ...
Lord Amanda A Department of - - 2014
Bronchopulmonary dysplasia (BPD) is a common long-term complication in premature newborns requiring ventilatory support and is the most common cause of chronic diffuse lung disease in this population. We present the clinical course of a premature newborn with a complicated neonatal respiratory course that was initially thought to be related ...
Zin Andrea A AA Department of Clinical Research, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, RJ, Brazil, - - 2014
To assess the additional cost of incorporating the detection and treatment of retinopathy of prematurity (ROP) into neonatal care services of Brazil's Unified Health System (SUS). A deterministic decision-tree simulation model was built to estimate the direct costs of screening for and treating ROP in neonatal intensive-care units (NICUs), based ...
El-Khuffash Afif A Department of Pediatrics, The Rotunda Hospital, Dublin, - - 2014
Background:We evaluated the clinical effectiveness of variable courses of paracetamol on patent ductus arteriosus (PDA) closure and to examine its effect on the in vitro term and preterm murine ductus arteriosus (DA).Methods:Neonates received one of three paracetamol regimens: short course of oral paracetamol (SCOP); long course of oral paracetamol (LCOP); ...
Morgan As A Institute for Women's Health, UCL, London, - - 2014
To evaluate the relationship of steroid, tocolysis and caesarean delivery to the chances of the baby being born with a heart rate >100 at 5 min after birth ("good condition") and of death in labour or the delivery room ("perinatal death"). Prospective cohort of all singleton births in England in ...
Shahid Shaneela S Division of Neonatology, Department of Pediatrics, McMaster University and Children's Hospital Hamilton, - - 2014
Absence of guidelines on umbilical arterial catheter (UAC) and umbilical venous catheter (UVC) use and inability to predict the hospital course may sway the frontline staff to overuse umbilical catheters in preterm infants. Our objective was to evaluate the feasibility of implementing guidelines standardizing the use of umbilical catheters and ...
Day Jane - - 2014
After spending three months as a clinical midwifery tutor at a remote hospital in Zambia, where I helped to train student midwives and other students, my interest in infant massage was ignited, having witnessed the benefits of massage to both mother and baby. Once back in the UK, I trained ...
Mori Mari M Department of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Tokyo, - - 2014
Although rectal bleeding in infancy (RBI) is not a rare phenomenon, the clinical course of RBI is not fully understood. To investigate the outcome and pathogenesis of RBI, especially when concomitant with food protein-induced proctocolitis (FPIP) and neonatal transient eosinophilic colitis (NTEC), 22 neonates with rectal bleeding with FPIP and ...
Ifflaender Sascha S Department of Neonatology and Pediatric Intensive Care, Medizinische Fakultät Carl Gustav Carus an der TU Dresden, - - 2014
A significant proportion of preterm infants have dolichocephaly and/or deformational plagiocephaly (DP) at term equivalent age. However, quantitative data on the clinical course after discharge is limited in these infants. To quantify the individual course of cranial symmetry and proportion in infants born <32 gestational weeks up to six months ...
Berkun Y Y 1Departments of Pediatrics; Obstetrics and Gynecology; Neonatology; Pediatric Neurology; National Hemophilia Center and Institute of Thrombosis and Hemostasis, Sheba Medical Center, Tel Hashomer, Israel and Sackler Medical School, Tel Aviv University, Tel Aviv, - - 2014
Objective Antiphospholipid syndrome (APS) may present with thrombosis and persistently elevated titers of antiphospholipid antibodies (aPL) in the neonatal period. Our aim was to investigate the course and impact of elevated titers of aPL in a cohort of infants presenting with either perinatal arterial ischemic stroke (PAS) or cerebral sinus ...
Sinha Renu R Departments of Anaesthesiology and Intensive Care, Rajendra Prasad Institute of Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, - - 2014
Premature infants scheduled for surgery under general anesthesia are more prone to cardio-respiratory complications. Risk factors include post-conception age (PCA), cardiac and respiratory disease, anemia and opioid administration. This retrospective study evaluates the perioperative management and post-operative course (apnea and bradycardia) in premature infants undergoing surgery for retinopathy of prematurity ...
Kadivar Maliheh M Department of Neonatal Care Unit, Children's Hospital Medical Center, Tehran University of Medical Sciences, Tehran, - - 2014
Congenital granular cell tumor (GCT) is a relatively rare intraoral benign tumor, approximately 200 cases of which have been reported in the neonatal period worldwide. The newborn infant may have feeding problems and respiratory difficulties due to airway obstruction. This lesion may be diagnosed by prenatal ultrasonography and simple resection ...
Puzik Alexander - - 2014
In term newborns meconium ileus is frequently associated with cystic fibrosis. Reports on meconium ileus in preterm infants being diagnosed with cystic fibrosis early after birth are very scarce. Associations between genotype and phenotype in cystic fibrosis and its particular comorbidities have been reported. Two extremely preterm twin infants (26 ...
Herskovic Ethel E Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 E. Chicago Ave, Chicago, IL, 60611, USA, - - 2014
Reported cases of metastases to the placenta are uncommon, and maternal transmission of tumor to the fetus is even more infrequent. However, vertical transmission of tumor can occur and should be considered as a potential etiology of malignancy in newborns and infants born to mothers with a history of cancer ...
van Wijk Renske M RM Department Health Technology and Services Research, Institute of Innovation and Governance Studies, University of Twente, Drienerlolaan 5, 7522 NB, Enschede, - - 2014
To determine the effectiveness of helmet therapy for positional skull deformation compared with the natural course of the condition in infants aged 5-6 months. Pragmatic, single blinded, randomised controlled trial (HEADS, HElmet therapy Assessment in Deformed Skulls) nested in a prospective cohort study. 29 paediatric physiotherapy practices; helmet therapy was ...
Mitchell Hannah Katherine HK Department of Medical School, University of Nottingham, Nottingham, - - 2014
Preterm birth is an important cause of neonatal morbidity and mortality globally. Uganda has one of the highest rates of preterm birth in East Africa but few resources to care for these infants. This case highlights the clinical course of an extremely premature infant born at 26 weeks gestation to a ...
Wang Zong-Hua ZH Department of Ophthalmology, General Hospital of Beijing Military Command of People's Liberation Army, Beijing 100700, - - 2014
To assess the relative effect of birth weight and gestational age on retinopathy of prematurity (ROP) using preterm twin pairs discordant for birth weigh in a tertiary neonatal intensive care unit in China. Fifty-six discordant twin pairs of 112 preterm infants were retrospectively analyzed. The twin pairs were divided into ...
Dougan Grace C GC Department of Pediatrics, University of South Florida Morsani College of Medicine, Tampa, - - 2013
A male infant was diagnosed with partial androgen insensitivity caused by a novel mutation in the androgen receptor. At 3.5 months of age, he received 100 mg of testosterone intramuscularly over the course of 3 months to increase phallic size. He developed pubic hair after 5 months and signs of ...
Hofer N - - 2013
Aim of this study was to describe the course of perinatal factors in neonates with meconium aspiration syndrome (MAS) from 1990 to 2010 and to determine risk factors for a severe course of the disease.All neonates with MAS hospitalized in our level III neonatal intensive care unit from 1990 to ...
Marx Carolin - - 2013
Background:Human milk oligosaccharides (HMO) represent the third most abundant component of human breast milk. More than a hundred structurally distinct HMO have been identified, and the HMO composition varies between mothers as well as over the course of lactation. Some newborn infants receive donor milk (DM) when their mother's own ...
Wong D - - 2013
To compare mortality, short-term morbidity and long-term neurodevelopmental outcomes of <29 week premature infants with antenatal steroid exposure (none, incomplete and complete). Multicentre retrospective cohort study, within a geographically defined area in Australia served by a network of 10 neonatal intensive care units (NICUs), of infants <29 weeks gestational age, ...
Kiat-Amnuay Sudarat - - 2013
We report the first example, to our knowledge, of a frictional keratosis from exuberant sucking in a breastfeeding infant. A 2-month-old girl was referred for evaluation of a well-demarcated, nonsloughing white keratotic plaque of the lower lip mucosa, just inside the vermilion border. The plaque had a slightly irregular surface, ...
Jon Cindy - - 2013
We present an infant who was born premature at 23 weeks gestation with bronchopulmonary dysplasia and a SFTPC gene mutation, p.R167Q, who had a complicated neonatal course requiring 4 months of mechanical ventilation. Over time, his clinical course has improved, and he only requires oxygen by nasal cannula and low ...
Kiliś-Pstrusińska Katarzyna - - 2013
Spontaneous kidney rupture could develop in the course of posterior urethral valve (PUV), the most common cause of outflow urinary tract obstruction in male infants. However, urinary extravasation is a rare complication among this group of children. Our case report presents diagnostic difficulties connected with spontaneous kidney rupture due to ...
Bancalari Eduardo - - 2013
Because mechanical ventilation is associated with severe complications in premature infants, it is important to limit its duration as much as possible. This can be accomplished by using startegies that preserve spontaneous respiration such as patient triggered and volume target ventilation. The use of respiratory stimulants and nasal CPAP or ...
Rini Regina A - - 2013
In a recent paper, Giubilini and Minerva argue for the moral permissibility of what they call 'after-birth abortion', or infanticide. Here I suggest that they actually employ a confusion of two distinct arguments: one relying on the purportedly identical moral status of a fetus and a newborn, and the second ...
Haworth Joshua L - - 2013
A normal time-course for the acquisition of sitting is essential. A delay in sitting may affect other developmental milestones, resulting in deficiencies in overall skill. Therefore, our aim was to identify variables whose measures at the very beginning of sitting would allow for the projection of the evolution of the ...
Chawla Sanjay - - 2013
Abstract Objective: To compare the neurodevelopmental outcomes at 18-22 months' corrected age of extremely premature infants exposed to a complete course, an incomplete course or no dose of antenatal steroids (ANS). Methods: Retrospective chart review of extremely premature (< 28 weeks gestational age) neonates over a 3 year period. Neurodevelopmental ...
Oppenheimer Julia E JE University of New Mexico, USA. - - 2013
This study examined mothers' physiological reactivity in response to infant distress during the Still-Face Paradigm. We aimed to explore normative regulatory profiles and associated physiological and behavioral processes in order to further our understanding of what constitutes regulation in this dyadic context. We examined physiological patterns--vagal tone, indexed by respiratory ...
James Deeptiman - - 2013
Burkoholderia pseudomallei is an emerging cause of localized musculoskeletal infections. We report the case of a 9-month-old infant with isolated primary chronic osteomyelitis of the fifth metatarsal. Radiographs showed expansion and thickening of the cortex. The metatarsal had lytic lesions with scalloped margins; no periosteal reaction or sequestration was seen. ...
Neuhausser Werner M WM Division of Reproductive Endocrinology & Infertility, Beth Israel Deaconess Medical Center/Boston IVF, Harvard Medical School, Boston, MA, - - 2013
We present here a case of vasa previa in a multipara, diagnosed at the time of her late second trimester ultrasonogram. The patient subsequently underwent an elective cesarean section after 37 weeks gestation, giving birth to a healthy child with an uneventful post-partum, neonatal and infant course. At the time ...
Oppenheimer Stephen - - 2012
In 1978, I returned from a 2-year government posting as provincial paediatrician to East and West Sepik provinces of Papua New Guinea (PNG), having already enrolled on the Diploma of Tropical Medicine and Hygiene (DTM&H) course at the Liverpool School of Tropical Medicine. I had been too late to enrol ...
Spoel Marjolein M Intensive Care and Department of Pediatric Surgery, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands. m.spoel @ - - 2013
Several studies have evaluated short-term neonatal outcome in infants with congenital lung lesions (CLL) but clinical course and lung function in the longer term have not yet been documented. We hypothesized that clinical course and lung function would be negatively affected by surgical resection. To evaluate respiratory symptoms and lung ...
Connelly Kara J - - 2012
We report the cases of 3 infants with congenital hypothyroidism detected with the use of our newborn screening program, with evidence supporting excess maternal iodine ingestion (12.5 mg/d) as the etiology. Levels of whole blood iodine extracted from their newborn screening specimens were 10 times above mean control levels. Excess ...
Leung Angela M AM Section of Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine, 88 East Newton St., Boston, MA 02118, USA. - - 2012
Breastfed infants rely on maternal iodine for thyroid hormone production required for neurodevelopment. Dietary iodine among women of childbearing age in the United States may be insufficient. Perchlorate (competitive inhibitor of the sodium/iodide symporter [NIS]) exposure is ubiquitous. Thiocyanate, from cigarettes and diet, is a weaker NIS inhibitor. Environmental perchlorate ...
Kapil Umesh - - 2012
In severe iodine deficient areas, iodine deficiency has been documented to be an important etiological factor leading to poor fetal growth and development. Iodine is essential for physical growth and development of the central nervous system of the fetus. Iodine deficiency in pregnant mothers leads to increased incidence of infertility ...
Milewski Antoni V - - 2012
Pandas are endemic to iodine-poor environments and appear to be specialized for a goitrogenic staple diet. In particular, the importance of thiocyanate in bamboos might possibly have been overlooked in captive breeding programs. Although excreted in urine, thiocyanate first antagonizes absorption of iodine by the thyroid (of parent, fetus and ...
Dilli Dilek - - 2012
To investigate the role of interleukin-6 (IL-6) and C-reactive protein (CRP) in non-thyroidal illness (NTI) in premature infants. Serum levels of IL-6 and CRP, thyroid-stimulating hormone (TSH), total thyroxine (T4), free T4 (fT4), total triiodothyronine (T3), and free T3 (fT3) were determined at the 1st, 2nd and 4th weeks of ...
Leung Angela - - 2012
Background: Breastfed infants rely on maternal iodine for thyroid hormone production required for neurodevelopment. Dietary iodine among women of childbearing age in the United States may be insufficient. Perchlorate (competitive inhibitor of the sodium/iodide symporter [NIS]) exposure is ubiquitous. Thiocyanate, from cigarettes and diet, is a weaker NIS inhibitor. Environmental ...
Moore Gregory P - - 2012
To document the rate of surgical ligation of a patent ductus arteriosus (PDA) in extremely premature infants who had received more than one course of indomethacin. Outcomes were compared among three subgroups (ligation, further indomethacin and no further treatment) of infants who received at least one course of indomethacin, and ...
Kochi Mahsa Hoshmand - - 2012
Administration of radioactive iodine to a pregnant woman for thyroid ablation has been shown to affect neonatal thyroid levels. Thus, there is a theoretical risk in affecting a neonate's thyroid level upon birth with prior administration of intravenous contrast containing iodine to a pregnant woman during a computed tomographic scan. ...
Belfort Mandy B - - 2012
Iodine is critical for normal thyroid hormone synthesis and brain development during infancy, and preterm infants are particularly vulnerable to the effects of both iodine deficiency and excess. Use of iodine-containing skin antiseptics in intensive care nurseries has declined substantially in recent years, but whether the current dietary iodine intake ...
Maitusong Riziwanguli - - 2012
It has been 11 years since newborn screening started in Zhejiang in 1999. The aim of this study was to analyze and summarize the status of newborn screening in Zhejiang from 1999 to 2009. Blood samples were collected from the heels of newborns 72 hours after birth. We have conducted ...
Hashemipour Mahin - - 2012
Considering the role of maternal thyroid stimulating hormone (TSH) receptor blocking antibody (TRAb) in the etiology of congenital hypothyroidism (CH), this study aimed to determine TRAb among patients with CH in Isfahan, Iran. In this case-control study, patients with CH and their mothers were compared with a group of healthy ...
Lista Gianluca - - 2012
Even if non invasive respiratory support is widespread used in the management of respiratory failure, nevertheless mechanical ventilation and surfactant replacement are standard care for many preterm infants with respiratory distress syndrome (RDS). The interaction between exogenous surfactant and different modalities of ventilatory support are very important and can influence ...
Obeid Rawad - - 2012
Neonatal hyperthyroidism is a rare condition caused either by transplacental passage of thyroid-stimulating immunoglobulins from a mother with Graves' disease or by activating mutations of the thyrotropin receptors and α-subunit of G-protein. The clinical features may vary. We report a case of neonatal thyrotoxicosis in an infant born to a ...
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