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Landers Susan - - 2013
Donor human milk has emerged as the preferred substrate to feed extremely preterm infants, when mother's own milk is unavailable. This article summarizes the clinical data demonstrating the safety, efficacy, and cost-effectiveness of feeding donor human milk to premature babies. It describes the current state of milk banking in North ...
Watt Kevin K Duke University, Pediatrics, Duke Clinical Research Institute, P.O. Box 17969, Durham, NC 27715, USA. - - 2013
Invasive fungal infections in infants admitted to the neonatal intensive care unit are common and often fatal. The mainstay of therapy against invasive fungal infections is antifungal agents. Over the last two decades, the development and approval of these drugs evolved tremendously, and the azole class emerged as important agents ...
Davis Natalie Louise NL Boston Children's Hospital Division of Newborn Medicine, Boston, MA 02115, USA. - - 2013
The American Academy of Pediatrics (AAP) recommends that all preterm neonates undergo a period of observation in a car safety seat before discharge, known as the Infant Car Seat Challenge (ICSC), to monitor for respiratory immaturity and the risk of adverse cardiopulmonary events in the upright position. However, no universal ...
Tagare Amit - - 2013
Bubble continuous positive airway pressure (BCPAP) is a low cost nasal CPAP delivery system with potential benefits to developing nations.Objective: To compare the efficacy and safety of BCPAP with ventilator-derived CPAP (VCPAP) in preterm neonates with respiratory distress.Methods: In a randomized controlled trial, preterm neonates with Silverman-Anderson score ≥4 and ...
Lu Chun-Yi CY Department of Pediatrics, National Taiwan University Hospital, Taipei 100, - - 2013
This Phase-IV study evaluated the human rotavirus (RV) vaccine Rotarix (RIX4414) to provide additional local clinical data to the Taiwan Food and Drug Association (NCT01198769). Healthy infants aged 6-12 weeks who were given a hepatitis B immunoglobulin (HBIg) dose after birth, received two doses of RIX4414 (0, 2-month schedule). Anti-RV ...
Daetwyler K - - 2013
Therapeutic hypothermia has become a standard neuroprotective treatment in term newborn infants following perinatal asphyxia. Active cooling with whole body surface or head cooling is complex, expensive and often associated with initial hypothermic overshoot. We speculated that passive cooling might suffice to induce and maintain hypothermia. We analysed 18 asphyxiated ...
van Beelen Mirjam E J - - 2013
BACKGROUND: Unintentional falls and poisonings are major causes of death and disability among infants. Although guidelines are available to prevent these injuries, safety behaviours are not performed by parents, causing unnecessary risks. Little is known about safety behaviours of first-time parents and whether they behave according to these guidelines. AIMSOBJECTIVESPURPOSE: ...
Pauliah Shreela S - - 2013
Although selective or whole body cooling combined with optimal intensive care improves outcomes following neonatal encephalopathy in high-income countries, the safety and efficacy of cooling in low-and middle-income countries is not known. We performed a systematic review and meta-analysis of all published randomised or quasi-randomised controlled trials of cooling therapy ...
Veltman Larry - - 2013
Underwater birthing has become a popular birth practice in some areas of the country. Although many of these deliveries occur in a home birth setting, the practice has also been implemented in hospitals and birthing centers. There is continued controversy about the risks and benefits of underwater birthing (as opposed ...
Kelly Lauren E - - 2013
Neonates are commonly exposed to maternal codeine through breast milk. Central Nervous System (CNS) depression has been reported in up to 24% of nurslings following codeine exposure. In 2009, we developed guidelines to improve the safety of codeine use during breastfeeding based on previously established pharmacogenetic and clinical risk factors. ...
Alfaleh K - - 2013
Probiotics are live microbial feed supplements that beneficially affect the recipient by improving intestinal balance. In an updated systematic review, nineteen trials randomizing more than 2800 infants were included. In a meta-analysis of trial data, enteral probiotic supplementation significantly reduced the incidence of severe necrotizing enterocolitis (typical RR 0.35, 95% ...
- - 2013
Intrapartum complications are responsible for approximately half of all maternal deaths, and two million stillbirth and neonatal deaths per year. Prolonged second stage of labour is associated with potentially fatal maternal complications such as haemorrhage and infection and it is a major cause of stillbirth and newborn morbidity and mortality. ...
Lokeshwar M R MR Department of Paediatrics, Kashyap Nursing Home, Mumbai Pediatrics, Imperial Mahal, Mumbai, Maharashtra India. - - 2013
To evaluate the immunogenicity and safety of a pentavalent rotavirus vaccine (PRV) in Indian infants. Open-label, single-arm multicentric study. Hospital facilities (out patients): One hundred and ten (110) healthy Indian infants were enrolled between the ages of 6 weeks and 12 weeks. Three doses of oral pentavalent rotavirus vaccine (PRV) ...
Ojha Shalini - - 2012
AIM: Heated humidified high-flow nasal cannula oxygen (HHHFNC) is a relatively new form of respiratory support and is increasing in popularity despite lack of supportive evidence and amid safety concerns. We investigated the prevalence of its use in tertiary neonatal units in the UK. METHOD: Electronic survey. RESULTS: 57 units ...
Shad Roona - - 2012
Safety pins are not commonly aspirated objects in infants and form only a small fraction of all the metallic foreign body (FB) which accounts for 4.4% of all foreign bodies found in tracheobronchial tree. Bronchoscopy procedure has various complications, in addition to failure to remove FB due to its impaction, ...
Struijs Marie-Chantal - - 2012
BACKGROUND & AIMS: Efforts are directed at reaching the optimal composition of pediatric amino acids (AA) infusions. The goal was to demonstrate the safety and efficacy of a newly developed parenteral AA solution containing alanyl-glutamine (GLN-AA) compared to Standard-AA. METHODS: This is a randomized (2:1), double-blind, multicentre clinical pilot trial. ...
Mosca F - - 2012
Respiratory failure in the premature infants remains a difficult challenge. An alternative to the use of nasal continuous positive airway pressure (NCPAP) as a non-invasive modality to support respiratory distress in premature infants has been the recent introduction of high flow nasal cannula (HFNC) devices in many neonatal units. There ...
Tam Bonnie - - 2012
In this study, we evaluated the efficacy and safety of acetazolamide in the management of chronic metabolic alkalosis in neonates and infants with chronic respiratory insufficiency. A retrospective chart review of 90 patients treated with acetazolamide between 2006 and 2007 admitted to the neonatal intensive care unit was performed. Blood ...
Manley Brett J - - 2012
Background: High-flow nasal cannulae (HFNC) are gaining in popularity as a form of non-invasive respiratory support for preterm infants in neonatal intensive care units around the world. They are proposed as an alternative to nasal continuous positive airway pressure (NCPAP) in a variety of clinical situations, including post-extubation support, primary ...
Cohen-Wolkowiez Michael M Department of Pediatrics, Duke University, Durham, North Carolina 27715, - - 2012
Intra-abdominal infections are common in young infants and lead to significant morbidity and mortality. Meropenem is a broad-spectrum antimicrobial with excellent activity against pathogens associated with intra-abdominal infections. The purpose of this study was to determine the safety and effectiveness of meropenem in young infants with suspected or complicated intra-abdominal ...
Labiner-Wolfe Judith - - 2012
Background: Many mothers express and store their milk to later feed to their infant. Health organizations providerecommendations on expressed milk storage and handling because these practices can affect milk quality and safety. However, little information exists on US mothers' practices.Objective: To describe how US mothers of healthy infants store and ...
Cho June I - - 2012
Male vulnerability in health and growth outcomes has often been reported in very low birth weight (VLBW) preterm neonates. On the basis of gender-difference theories, possible associations were explored between the levels of postnatal salivary testosterone/cortisol and the outcomes of neonatal health/growth. This study used an exploratory and comparative research ...
Couch Robert - - 2012
Premature infants are known to have elevated 17-hydroxyprogesterone and adrenal androgen concentrations immediately after birth, but the levels decrease rapidly. Virilization of normal premature female infants as a result of these high androgens has not been described. Three premature female infants born at 24 to 25 weeks' gestation, with birth ...
James William H - - 2012
Baron-Cohen hypothesized that a cause of autism in infants is exposure to high concentrations of intrauterine testosterone concentrations. Some of the subsequent research on this hypothesis has focused on the possibility that the source of this testosterone is the fetus; however, this review shows that if the source is taken ...
Wolf Alex - - 2012
The author responds to an article published in the Journal by Joseph J. Mangano and Janette D. Sherman suggesting that an increase in U.S. deaths shortly after Japan's Fukushima nuclear plant accident could be attributed to radiation from this accident arriving in the United States. The author writes that the ...
Young Marisa R - - 2012
Several sub-Saharan African countries plan to scale-up infant male circumcision (IMC) for cost-efficient HIV prevention. Little data exist about the safety of IMC in East and southern Africa. We calculated adverse event (AE) rate and risks for AEs associated with introduction of IMC services at five government health facilities in ...
Marini Herbert - - 2012
Genistein aglycone, one of the soy isoflavones, has been reported to be beneficial in the treatment of menopausal vasomotor symptoms, osteoporosis, and cardiovascular diseases, as well as in a variety of cancers. However, issues of potential harm on thyroid function resulting from soy isoflavones consumption have been raised. Much of ...
Vidaeff Alex C - - 2011
Preterm premature rupture of membranes (PPROM) is an obstetrical complication associated with high neonatal morbidity and mortality. The current management of PPROM focuses on neonatal benefit and includes the ancillary use of corticosteroids for fetal maturation. The purpose of this work was to provide a comprehensive and unbiased review of ...
Odd David Edward - - 2011
Objective: The goal of this study was to investigate the association of poor birth condition with long-term social and economic outcomes at 25 to 31 years of age. Methods: This was a population-based cohort study using data derived from linkage of routinely collected Swedish data. All term infants born in ...
Bremner J Gavin - - 2011
From birth, infants detect associations between the locations of static visual objects and sounds they emit, but there is limited evidence regarding their sensitivity to the dynamic equivalent when a sound-emitting object moves. In 4 experiments involving thirty-six 2-month-olds, forty-eight 5-month-olds, and forty-eight 8-month-olds, we investigated infants' ability to process ...
Kamath Beena D - - 2011
Respiratory distress syndrome (RDS) is a major contributor to neonatal mortality worldwide. However, little information is available regarding rates of RDS-specific mortality in low-income countries, and technologies for RDS treatment are used inconsistently in different health care settings. Our objective was to better understand the interventions that have decreased the ...
Zhang Yuanting Y Office of Regulations, Policy and Social Sciences, Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, Maryland, USA. - - 2011
To describe the use of dietary botanical supplements and teas among infants, the characteristics of mothers who give them the specific botanical supplements and teas used, reasons for use, and sources of information. We used data from the Infant Feeding Practices Study II, a longitudinal survey of women studied from ...
Cass Darrell L - - 2011
The field of neonatal surgery is now inextricably linked to the field of obstetrics. Neonatologists and surgical specialists experienced with the postnatal management and outcomes of infants with various disorders now look in utero along with obstetricians and fetal medicine specialists to characterize the development and well-being of fetuses with ...
Brown Amy - - 2011
brown a., raynor p. & lee m. (2011)  Healthcare professionals' and mothers' perceptions of factors that influence decisions to breastfeed or formula feed infants: a comparative study. Journal of Advanced Nursing ABSTRACT: Aim.  This article is a report of a study comparing healthcare professionals' and mothers' perceptions of factors that ...
Lundberg Pranee C PC Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden. - - 2012
to describe breast-feeding attitudes and practices among Vietnamese women in Ho Chi Minh City. a descriptive qualitative study was used. The theory of planned behaviour provided the conceptual framework. the Well-baby Clinic, Department of Obstetrics and Gynaecology of a university hospital in Ho Chi Minh City, Vietnam. 23 voluntary Vietnamese ...
Thomson Gill - - 2011
Given the overwhelming evidence for the benefits of breastfeeding, and yet the low prevalence rates in the UK, it is crucial to understand the influences on women's infant feeding experiences to target and promote effective support. As part of an evaluation study of the implementation of the UNICEF UK Baby ...
Wuehler Sara E - - 2011
Progress towards reducing mortality and malnutrition among children <5 years of age has been less than needed to achieve related Millennium Development Goals. Therefore, several international agencies joined to 'Reposition children's right to adequate nutrition in the Sahel', starting with a situational analysis of current activities related to infant and ...
Wuehler Sara E - - 2011
Progress towards reducing mortality and malnutrition among children <5 years of age has been less than needed to achieve related Millennium Development Goals (MDGs). Therefore, several international agencies joined to 'reposition children's right to adequate nutrition in the Sahel', starting with an analysis of current activities related to infant and ...
Wuehler Sara E - - 2011
Progress towards reducing mortality and malnutrition among children <5 years of age has been less than needed to achieve related Millennium Development Goals (MDGs). Therefore, several international agencies joined to 'Reposition children's right to adequate nutrition in the Sahel', starting with an analysis of current activities related to infant and ...
Spong Catherine Y - - 2011
Infant mortality, stillbirths, and preterm births are major public health priorities with significant disparities based on race and ethnicity. Interestingly, when evaluating the rates over the past 30 to 50 years, the disparity persists in all three and is remarkably consistent. In the United States, the infant mortality rate is ...
Scott Lisa S - - 2011
The effects of individual versus category training, using behavioral indices of stimulus discrimination and neural (ERPs) indices of holistic processing, were examined in infants. Following pretraining assessments at 6 months, infants were sent home with training books of objects for 3 months. One group of infants was trained with six ...
Thibeau Shelley - - 2011
The immune properties of breastmilk are the most effective preventative means of reducing infant mortality through both passive and active immunity. Breastmilk for term infants has been linked to decreased incidence of respiratory and ear infections and gastrointestinal distress. This protection is even more important for the preterm infant. Prematurity ...
Sehgal Arvind - - 2011
While extremely low-birthweight infants are at a higher risk of haemodynamic instability, management strategies can be highly variable and may lack scientific validation. The aetiology of cardiovascular compromise can be diverse. Volume replacements, cardiotropes (dobutamine, dopamine, epinephrine and milrinone) and hydrocortisone supplementation are common interventions. Most often, therapy is driven ...
Bronstein Janet M - - 2011
To examine the factors associated with delivery of preterm infants at neonatal intensive care unit (NICU) hospitals in Arkansas during the period 2001-2006, with a focus on the impact of a Medicaid supported intervention, Antenatal and Neonatal Guidelines, Education, and Learning System (ANGELS), that expanded the consulting capacity of the ...
DeSantis Andrea A Department of Developmental Medicine, Children's Hospital, Child Development Unit, 1295 Boylston Street, Boston, MA 02215, United States. - - 2011
Traditionally, developmental psychology, occupational/physical therapy, and behavioral pediatrics view similar infant behaviors from temperament, sensory processing, or neurobehavioral theoretical perspectives. This study examined the relations between similar and unique summary scores of three infant assessments (Early Infancy Temperament Questionnaire - EITQ, the Infant Sensory Profile - ISP, and the NICU ...
Cole Tim J - - 2012
The decision to adopt the new WHO standard in the UK necessitated substantial changes to the neonatal section of the chart, including separation of the preterm UK birth weight reference from the WHO standard. The evidence-based design process has led to several novel features that could be generally applied in ...
Avery Alexis B - - 2011
The objective of the current study was to better understand how pregnant women and male partners conceptualize infant feeding and support for breastfeeding. Information was collected through 18 focus group interviews in 3 major US cities. There were 121 focus group participants of varying professions and income levels. Half were ...
Fewtrell Mary - - 2011
PURPOSE OF REVIEW: Early life nutrition may influence later osteoporosis risk. Preterm infants are at particular risk of suboptimal early nutrition, which is associated with poor neonatal bone mineralization and metabolic bone disease, but it is unclear whether this has long-term consequences for bone health. This review discusses the long-term ...
Carolan Mary - - 2011
BACKGROUND: stress during pregnancy is common and has been linked to a range of poorer maternal and infant outcomes. Treatment options are few, however, due to difficulties of diagnosis and concerns about the impact of medication on the developing fetus. Singing is an activity with stress reducing and other benefits ...
Smith Caren G - - 2011
Necrotizing enterocolitis (NEC ) can be a devastating disease in the NIC U population. The current standard of practice of not providing enteral nutrition to the critically ill and the premature infant is thought to result in pathophysiologic changes of the gastrointestinal (GI) tract that may result in the development ...
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