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Pick Verena V Department of Business Administration and Healthcare Management, University of Cologne, Cologne, - - 2014
We investigated the associations between staff work characteristics, parents' experiences and a number of medical outcome measures. This explorative multi-centre study took place in the neonatal intensive care units (NICUs) of five German university hospitals between 2009 and 2011. We assessed staff work characteristics by surveying 126 NICU nurses and ...
Spatz Diane L DL University of Pennsylvania, Philadelphia, and the Lactation Program, Children's Hospital of Philadelphia, Pennsylvania (Dr Spatz); University of Pennsylvania, Philadelphia (Ms Schmidt), and Director of Patient and Family Services-Nutrition Services, Children's Hospital of Philadelphia, Pennsylvania (Ms - - 2014
Current hospital practices surrounding the use of human milk and fortification are suboptimal. Safety of milk preparation should be a priority, as should optimization of the milk to meet the nutritional needs of hospitalized infants. This article describes the implementation of a human milk management center (HMMC) at a children's ...
Morton Jane - - 2013
Best postpartum breastfeeding practices must address the caloric needs of all infants, including vulnerable infants, while enabling long-term, exclusive breastfeeding. An adequate subsequent milk supply depends on early, frequent and effective colostrum removal. A combination of hand expression of colostrum, spoon-feeding and unrestricted breastfeeding provide more milk for infants and ...
Strand H - - 2013
To compare attitudes towards Kangaroo Mother Care (KMC) among staff in two high-tech neonatal intensive care units, which provided parents with different opportunities to get involved in their infants' care. Questionnaires were completed by healthcare staff in Unit A, which provided parents with unrestricted access so that they could provide ...
Oral Resmiye - - 2013
abstract Objective: This project explored the impact of staff training on the rates of perinatal maternal and neonatal illicit drug testing. Methods: Controlled, retrospective chart review on 1,186 newborn and mother dyads from 2006 (pre-training control group) and on 1,861 dyads from 2009 (post-training study group) was completed. Differences between ...
Lelijveld Natasha - - 2013
Severe acute malnutrition (SAM) in infants aged <6 months is a major global health problem. Supplementary suckling (SS) is widely recommended as an inpatient treatment technique for infant <6 months SAM. Its aim is to re-establish effective exclusive breastfeeding. Despite widespread support in guidelines, research suggests that field use of ...
Plank Rebeca M RM Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA. - - 2013
Male circumcision can reduce the risk of heterosexually acquired HIV-1 infection in men. Neonatal male circumcision (NMC) has many potential advantages over circumcision at older ages, but little is known about its feasibility and safety in resource-limited settings. We performed a randomized trial in southeastern Botswana of Mogen clamp and ...
Turner Claudia - - 2013
A third of all deaths in children aged <5 years occur in the neonatal period. Neonatal intensive care is often considered too complex and expensive to be implemented in resource poor settings. Consequently the reductions that have been made in infant mortality in the poorest countries have not been made ...
Nii Okai Aryeetey Richmond R School of Public Health, University of Ghana, Legon, P,O, Box LG 13, Accra, Ghana. - - 2013
The Baby-Friendly Hospital Initiative (BFHI) has been implemented in Ghana since 1995. At the end of 2011, about 325 maternity facilities in Ghana had been designated Baby Friendly. However, none had been re-assessed for adherence to the Ten Steps to successful breastfeeding (Ten Steps). The current study re-assessed six maternity ...
Bar-Zeev Sarah J SJ Centre for Rural Health, North Coast; Sydney School of Public Health, University of Sydney, New South Wales, Sydney 2480, Australia. - - 2013
Remote dwelling Aboriginal infants from northern Australia have a high burden of disease and frequently use health services. Little is known about the quality of infant care provided by remote health services. This study describes the adherence to infant guidelines for anaemia and growth faltering by remote health staff and ...
Casey Denise M - - 2012
Necrotizing fasciitis (NF) is a severe infection involving the superficial fascia, subcutaneous tissue, and, occasionally, deeper tissue layers. Usual treatment is with surgical debridement in combination with antibiotics. In review of the literature there is one neonatal report of NF associated with necrotizing enterocolitis. We present a case report of ...
Calkavur Sebnem - - 2012
Purpose: Epidemic adenoviral keratoconjunctivitis can spread rapidly among preterm infants who frequently undergo ophthalmological examination. Here we present our experience on a nosocomial outbreak that affected 8 nursery staff members and 26 premature infants. We focus on the presentation and progress of the outbreak, the diagnosis of the disease and ...
Hassanein Sahar M A - - 2012
Abstract Objectives: To study the impact of interrupted loud noise in Neonatal Intensive Care Unit (NICU) on neonatal physiologic parameters, and apply methods to alleviate noise sources through teaching NICU's staff. Methods: Noise level measured at different day times and during different noisy events in the NICU. Changes in the ...
Ericson Jenny - - 2012
OBJECTIVE: To evaluate the effects of estimated breastfeeding on infant outcomes in comparison to test weighing and to describe staff members' experiences of estimated breastfeeding as a method for supporting the transition from tube feeding to breastfeeding. DESIGN: A mixed method evaluation. SETTING: Neonatal Intensive Care Unit (NICU) in Sweden. ...
Cleveland Angela Ahlquist - - 2012
Background. Candidemia is common and associated with high morbidity and mortality; changes in population-based incidence rates have not been reported.Methods. We conducted active, population-based surveillance in metropolitan Atlanta, Georgia, and Baltimore City/ County, Maryland (combined population 5.2 million), during 2008-2011. We calculated candidemia incidence and antifungal drug resistance compared to prior surveillance ...
Regazzi M - - 2012
The prevention and treatment of pediatric fungal infections are limited by the fact that not all antifungal drugs are approved for the pediatric age and appropriate dosages have not been established for each age group The management of neonates and infants with invasive fungal infection is becoming more complex with ...
Claure Nelson - - 2012
Abstract Premature infants frequently present with respiratory instability, which is associated with fluctuations in ventilation and gas exchange. Adjustment of respiratory support to the infant's needs is limited by staff availability and workload. Hence, automation is being explored as a way to improve the care of the premature infants. New ...
Chitnis Amit S AS Surveillance Branch, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. - - 2012
To assess trends in incidence of Candida spp. central line-associated bloodstream infections (CLABSIs) in US NICUs, 1999-2009. Data from NICUs participating in the National Nosocomial Infections Surveillance (1999-2004) and National Healthcare Safety Network (2006-2009) were analyzed. Overall and birth weight-specific incidence rates of Candida spp. CLABSIs per 1000 central line-days ...
Thakar Sumit - - 2012
Invasive craniocerebral aspergillosis, often encountered in an immunocompromised setting, is almost uniformly fatal despite radical surgical and medical management, and is frequently a necropsy finding. The authors report a unique, self-resolving clinical course of this aggressive infection in a 10-month-old infant. The infant was brought to the emergency services in ...
Rolnitsky Asaph - - 2012
Antifungal prophylaxis is increasingly used in very low birth weight (VLBW) infants who are at risk for severe fungal infections. Our objective was to assess the effectiveness of targeted fluconazole prophylaxis for high-risk VLBW infants. A retrospective cohort study with historical controls was performed. During the period 2007-2008, all high-risk ...
Castagnola E - - 2012
Fluconazole is a triazole antifungal agent that is widely used in the nursery. It is available in both intravenous and oral formulation, and is active against most of the fungal pathogens that require treatment when retrieved from culture samples in neonatal intensive care units. Although clinical use has been wide ...
Manzoni P - - 2012
Invasive disseminated neonatal aspergillosis is an uncommon disease, with only scattered reports in literature in the last few years. Here we report on a 25-week gestational age, 730 g at birth preterm female infant who developed on day-of-life 10 multiple cutaneous exhulcerative lesions in her right arm, trunk and abdomen. ...
Manzoni P - - 2012
Fungal colonisation by Candida spp. affects a high proportion of VLBW neonates in NICU. However, few data are available on the clinical characteristics of colonisation in preterm infants who are colonised at baseline via vertical transmission, compared to preterms who become colonised during their stay in NICU via horizontal transmission. ...
Kaufman D A - - 2012
Prevention of invasive Candida infections (ICI) is an achievable goal for every NICU and supported by A-1 evidence. Due to the incidence of ICI, high infection-associated mortality and neurodevelopmental impairment, antifungal prophylaxis should be targeted to infants <1000 g or ≤27 weeks gestation. There is A-1 evidence for both fluconazole ...
Greenberg Rachel G RG Department of Pediatrics, Duke University, Durham, NC, - - 2012
To assess the impact of empiric antifungal therapy for invasive candidiasis on subsequent outcomes in premature infants. This was a cohort study of infants with a birth weight ≤ 1000 g receiving care at Neonatal Research Network sites. All infants had at least one positive culture for Candida. Empiric antifungal ...
Leibovitz Eugene - - 2012
Invasive fungal infections represent the third-leading cause of late-onset sepsis in very-low-birth-weight infants (VLBWI) and have a high rate of infection-associated mortality. The infants at high risk for fungal sepsis are VLBWI with presence of additional risk factors that contribute to increased colonization and concentration of fungal organisms. Colonization with ...
Celebi Solmaz - - 2012
Background:  The aim of this study is to evaluate the risk factors, demographic features, treatment and clinical outcome associated with candidemia in neonatal intensive care unit (NICU) within a 8-year period. Methods:  The data of infants who were diagnosed as candidemia, were evaluated. Results:  Between January 2000 and December 2007, ...
Matsukura Takashi - - 2012
Context:According to a recent nationwide survey in Japan, a significant proportion of very low birth weight infants (VLBWI) develop late-onset circulatory collapse after the first week of life. Small doses of glucocorticoid are very effective in these patients, and relative adrenal insufficiency is suspected to be the main cause of ...
Testoni Daniela D Duke Clinical Research Institute, Duke University Medical Center, 2400 Pratt Street, Durham, NC 27705, - - 2012
Invasive fungal infections remain a significant cause of infection-related mortality and morbidity in preterm infants. Central nervous system involvement is the hallmark of neonatal candidiasis, differentiating the disease's impact on young infants from that among all other patient populations. Over the past decade, the number of antifungal agents in development ...
Li Meng-Ju - - 2012
Systemic fungal infections have high morbidity and mortality rates in neonates, especially neonates with an extremely low birth weight (ELBW). Here, we describe a 21-day-old ELBW female infant with an amphotericin B-unresponsive congenital Candida albicans infection that was treated with caspofungin. Blood sterilization was performed during the first episode, but ...
Clerihew Linda - - 2012
A variety of antifungal drugs, drug preparations and drug combinations are available to treat newborn infants with suspected or confirmed invasive fungal infection. There is a need to assess their relative merits. To assess the effect of treatment with different antifungal drugs, drug preparations or drug combinations on mortality and ...
Miranda Lourdes das Neves - - 2012
To evaluate Candida parapsilosis candidaemia in a neonatal unit over 7 years. Case series study. A 2000-bed tertiary-care university hospital at São Paulo, Brazil. Neonates hospitalised in a 63-bed neonatal unit. We evaluated the incidence of C parapsilosis fungemia in a neonatal unit from 2002 through 2008 and the main ...
Turner K K Department of Pediatrics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, - - 2012
Invasive candidiasis (IC) in the premature infant population is a common infection that results in substantial morbidity and mortality. For these patients, fluconazole is among the first line therapies to treat and prevent IC, and yet few prospective studies investigating its pharmacokinetics (PK) and safety have been performed in this ...
Kuiri-Hänninen Tanja - - 2011
Context:Postnatal pituitary-testicular activation in infant boys is well characterized. However, the ovarian response to pituitary activation in infancy is less well understood.Objective:The aim of the study was to compare postnatal developmental changes in the pituitary-ovarian axis in preterm and term infant girls.Participants and Design:Sixty-three infant girls, divided into three groups ...
Laurent Heidemarie K HK Department of Psychology, University of Wyoming, Laramie, Wyoming 82071, USA. - - 2011
Neural correlates of stress regulation via the hypothalamic-pituitary-adrenal (HPA) axis have been identified, but little is known about how these apply to real-world interpersonal stress contexts such as mother-infant interaction. We extended stress regulation research by examining maternal neural activation to infant cry related to HPA regulation with their infants. ...
Wiesel Awi - - 2011
So far, only a few studies investigated occupational exposure to ionizing radiation in pregnancy to cause birth defects (BDs). No association between BDs and ionizing radiation, although described for high-dose exposure, could ever be confirmed for employees, or specific job titles. Here, an explorative analysis of a prospective population-based birth ...
Askenazi David J - - 2011
To determine the independent impact of acute kidney injury (AKI) and renal replacement therapy (RRT) in infants and children who receive extracorporeal membrane oxygenation. Despite continued expertise/technological advancement, patients who receive extracorporeal membrane oxygenation have high mortality. AKI and RRT portend poor outcomes independent of comorbidities and illness severity in ...
Kojima Hideyuki - - 2011
The spiral scan with a wide detector row such as the 64-detector row computed tomography (CT) system may increase radiation exposure for infants because the irradiation range is wider than the planned range. The adaptive dose shield (ADS) prevents radiation exposure greater than the planned range. We examined the usefulness ...
Yu Cheng-Chung - - 2010
With rising numbers of extremely premature infants in the neonatal intensive care unit (NICU) who require multiple radiologic examinations for their complex medical conditions, concerns the risk of radiation exposure become a more prevalent issue. The biological effects from cumulative doses of both primary and secondary radiation can be particularly ...
Giliberti Paolo - - 2010
Shock defines a complex dysfunction of organ perfusion, that produces a status of cellular energy failure, resulting from an insufficient supply of oxygen and nutrients to tissues. The diagnosis of shock is very difficult because of the lack of sufficiently sensitive and specific clinical criteria, and is substantially based on ...
Hamon I - - 2010
Inhaled nitric oxide (iNO), commonly used for hypoxic neonates, may react with haemoglobin to form methaemoglobin (MetHb). MetHb monitoring during iNO therapy has been questioned since low doses of iNO are used. To evaluate the incidence of and identify risk factors associated with elevated MetHb in neonates treated with iNO. ...
Dennery Phyllis A - - 2010
To evaluate the use of oxygen in neonates in the past, present and future. The data are mainly from Pubmed with relevant published articles from the 1940s to the present with some information gathered from web searches. Studies evaluating the use of oxygen in premature and term infants through history ...
Gitto Eloisa - - 2011
Melatonin, an endogenously produced indoleamine, is a highly effective antioxidant, free radical scavenger, and a primary circadian regulator. Melatonin has important antioxidant properties owing to direct and indirect effects. It directly scavenges reactive oxygen and reactive nitrogen species, prevents molecular oxidation, improves mitochondrial physiology, and restores glutathione homeostasis. Its indirect ...
Cortez Josef - - 2011
Background. Diagnosis of necrotizing enterocolitis (NEC) in preterm neonates is challenging. We hypothesized that regional splanchnic oxygen saturation (rsSO(2)) measured by near-infrared spectroscopy (NIRS) is a biomarker for mesenteric perfusion. Objective. To evaluate feasibility and safety of continuous rsSO(2) monitoring in preterm infants in the first 14 days of life. Methods. Preterm neonates ...
Rowlands Helen E - - 2010
Bordetella pertussis is a common, underrecognized, and vaccine-preventable cause of critical illness with a high mortality in infants worldwide. Patients with severe cases present with extreme leukocytosis and develop refractory hypoxemia and pulmonary hypertension that is unresponsive to maximal intensive care. This may reflect a hyperviscosity syndrome from the raised ...
Smith Joann - - 2011
The purpose of this observational study was to characterize the clinical course of newborn infants with spontaneous pneumothorax and to identify those infants who eventually required further interventions. We performed a retrospective review of newborns with symptomatic spontaneous pneumothorax, born between January 2002 and December 2007. Seventy-six infants ≥36 weeks' ...
Dawson J A - - 2010
Pulse oximetry is commonly used to assist clinicians in assessment and management of newly born infants in the delivery room (DR). In many DRs, pulse oximetry is now the standard of care for managing high risk infants, enabling immediate and dynamic assessment of oxygenation and heart rate. However, there is ...
Baerts Willem - - 2011
In the clinical setting, episodes of desaturation in newborn infants are often treated by increasing the fraction of inspired oxygen (FiO(2)). To study the effect of an increase in FiO(2) on cerebral oxygenation during recovery from desaturation, as measured by near-infrared spectroscopy (NIRS). Peripheral arterial saturation (SaO(2)), NIRS-monitored cerebral saturation ...
Urlesberger Berndt - - 2010
OBJECTIVE: To evaluate regional tissue oxygenation of the brain and preductal and postductal peripheral (muscle) tissue during immediate transition after birth, and to correlate with peripheral preductal and postductal arterial oxygen saturation. STUDY DESIGN: We conducted a prospective observational study. With near-infrared spectroscopy (NIRS), changes in regional oxygen saturation of ...
Lavoie Pascal M - - 2010
The intravenous lipid emulsion (LIP) is a source of oxidants which may stimulate inflammation. Co-administration of parenteral multivitamins (MVP) with LIP prevents lipid peroxidation in light exposed TPN. We hypothesised that this modality of TPN administration affects systemic inflammation, which may be modulated by exposure to oxygen. Premature infants were ...
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