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Hazza Issa A IA Pediatric Department, Queen Rania Abdulla Children Hospital, Amman, - - 2014
Although hypercalcemia and hypercalciuria are known to occur in breast-fed pre-term infants, to the best of our knowledge, it has never been reported in a term baby previously. We report a term male baby who was followed-up during pregnancy for having bright kidneys, but a follow-up renal ultrasound (US) after ...
Emery Helen T - - 2014
The present study investigated maternal dispositional empathy and skin conductance level (SCL) reactivity to infant emotional cues as joint predictors of maternal sensitivity. Sixty-four mother-toddler dyads (31 boys) were observed across a series of interaction tasks during a laboratory visit, and maternal sensitivity was coded from approximately 55 minutes of ...
Kotzbauer David D Children's Healthcare of Atlanta in Atlanta, - - 2014
We reviewed the characteristics of infants less than 3 months of age with CNS HSV infection at our institution. Twenty-six cases were identified. The age range was 4 to 73 days. Most infants presented with fever, seizure activity, and skin lesions. The blood HSV PCR was positive in 91% of ...
Holme N N Leeds Teaching Hospitals NHS Trust, Leeds, - - 2014
50-100 babies are born per year to drug using mothers in Leeds. Local guidelines state maternal or neonatal urine toxicology (UT) should be sent if the mother is known to use illicit substances (with the mother's verbal consent). A local audit was conducted alongside a national survey of the use ...
Banerjee Jayanta J Homerton University Hospital NHS Foundation Trust, London, UK; Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK; The Portland Hospital for Women and Children, London, - - 2014
Almost 90% of extremely low birthweight infants receive red blood cell (RBC) transfusion during their stay in the neonatal unit (NNU). Currently most NNUs use a combination of clinical signs and laboratory findings such as hemoglobin (Hb), hematocrit (Hct), and cardiorespiratory or ventilation status to decide the need for RBC ...
Kiser Courtney C Pediatrics/Neonatology, Thomas Jefferson University/Nemours, Philadelphia, - - 2014
Chorioamnionitis (CAM) is a major risk factor for neonatal sepsis. At our institution, neonates exposed to CAM and intrapartum antibiotics are treated with prolonged antimicrobial therapy if laboratory values are abnormal despite a sterile blood culture. Recently, the Committee on the Fetus and Newborn (COFN) recommended a similar strategy for ...
Padula Michael A MA aDivision of Neonatology, bDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; and fDepartment of Pathology and Laboratory Medicine, cPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; and dDivision of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincnnati, Ohio; and eDivision of Neonatology, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, - - 2014
Bloodstream infections (BSI) remain a leading cause of morbidity and mortality among infants admitted to neonatal intensive care units (NICUs). At the time of evaluation for suspected BSI, presenting signs may be non-specific. We sought to determine the clinical signs and risk factors associated with laboratory-confirmed BSI among infants evaluated ...
Oliveira Carlos R CR Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX; Children's Medical Center, Dallas, - - 2014
To describe the results of brain magnetic resonance imaging (MRI) of infants with bacterial meningitis and how the findings affected clinical management. This retrospective study included all infants <12 months of age who were hospitalized at Children's Medical Center, Dallas and had culture-confirmed bacterial meningitis and a brain MRI from January ...
Levit Orly O From the *Department of Pediatrics and †Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, - - 2014
Late-onset sepsis (LOS) in very low birth weight (VLBW) infants is associated with significant morbidity and mortality. The ability to predict mortality in infants with LOS based on clinical and laboratory factors at presentation of illness remains limited. To identify predictors of sepsis-associated mortality from a composite risk profile that ...
Hernandez-de Mezerville Marcela M Hospital Nacional de Niños de Costa Rica Dr. Carlos Sáenz Herrera, San José, Costa Rica. - - 2014
Clostridium botulinum is known to cause descending paralysis in infants throughout the world. The subject of this study was a three-month-old Costa Rican boy who was hospitalized because of poor suction and feeding, hypotonia, and constipation. Clinical history and physical examination findings suggested infant botulism. Samples were sent to the ...
Alnimr Amani M AM Department of Microbiology, King Fahad University Hospital, College of Medicine, University of Dammam, Saudi - - 2014
Bacteremia due to Campylobacter spp. is rarely reported, and Campylobacter fetus is the species most commonly exhibiting vascular tropism, as occurred in this case report describing the diagnosis of C. fetus bacteremia in an infant presenting with respiratory tract infection. A 5-month-old baby, with undiagnosed failure to thrive, presented to ...
Dunphy-Lelii Sarah S Bard - - 2014
Traditional looking-time paradigms are often used to assess infants' attention to socio-cognitive phenomena, but the link between these laboratory scenarios and real-world interactions is unclear. The current study investigated hypothesized relations between traditional social-cognitive looking-time paradigms and their real-world counterparts in caregiver-infant social interaction. Seventy-five 10- to 12-month-old infants participated ...
Wu Jonathan A - - 2013
An infant born with hypospadias and no palpable gonads was diagnosed with persistent mullerian duct syndrome (PMDS) based on history, physical examination, laboratory testing, and radiologic imaging. A robot-assisted laparoscopic hysterectomy, right gonadal biopsy, and bilateral orchiopexies were performed without incident. Final pathology confirmed the diagnosis of PMDS. To our ...
Glatstein Miguel - - 2013
Atropa belladonna is a poisonous plant that can cause anticholinergic effects when ingested. Roots, leaves, and fruits of the plant contain the alkaloids atropine, hyoscyamine, and scopolamine, which can lead to an anticholinergic toxidrome; however, not all characteristics of the toxidrome are necessarily present in each case of poisoning. We ...
Altit Gabriel - - 2013
A 5-week-old full-term male infant presented to our institution with a history of multiple episodes of projectile, nonbilious vomiting. Laboratory investigations revealed a hypokalemic, hypochloremic metabolic alkalosis. On physical examination, an olive-shaped mass that was 2 cm long was palpated in the lower inner aspect of the right upper quadrant, ...
Oliveira Leonam Costa - - 2013
To determine the prevalence of fetal and neonatal deaths among patients with maternal near miss and the factors associated with this fatal outcome. The authors conducted a descriptive, cross-sectional, analyzing medical records of patients admitted to the ICU of a tertiary obstetric Recife (Brazil), between January 2007 and December 2010, ...
López Sergio - - 2013
Quality problem or issueIncorrect and excessive diagnosis of newborn infections in Nicaragua caused overcrowding in the neonatal intensive care units and unnecessary hospitalization.Initial assessmentA baseline study in nine hospitals found that none correctly utilized disinfectants, sterilization or hand hygiene and that diagnosis of neonatal sepsis was based primarily on clinical ...
Nosrati Adi - - 2013
To assess correlations between demographic, clinical and laboratory characteristics and the risk of serious bacterial infections (SBIs) in febrile <90-day-old infants. Medical records of all infants younger than 90 days of life hospitalized in our medical center (2006-2008) for evaluation of fever were retrospectively reviewed. Data on their clinical, laboratory ...
Wilson Patrick T PT Center for Global Health and Diseases, Case Western Reserve University, Cleveland, OH, USA. Electronic address: - - 2013
Transplacental transfer of antibodies from clinically malaria immune pregnant women to their fetuses is thought to provide passive protection against malaria during infancy. However, the presences and duration of functional antibodies against Plasmodium falciparum (Pf) in newborns has not been described. We used growth inhibition assays (GIA) to measure total ...
Risso Francesco M - - 2013
To investigate whether S100A1B and BB dimers are predictors of early perinatal death in newborns with perinatal asphyxia (PA). The study compared 38 full-term newborns with PA [neonatal death n=11; hypoxic ischaemic encephalopathy (HIE): n=27] with a control group of 38 healthy infants. Clinical and laboratory parameters were recorded at eight ...
Molnár Kriszta K 1st Department of Pediatrics, Semmelweis University, 1083 Budapest, - - 2013
To investigate the characteristics of mucosal lesions and their relation to laboratory data and long-term follow up in breast-fed infants with allergic colitis. In this study 31 breast-fed infants were prospectively evaluated (mean age, 17.4 wk) whose rectal bleeding had not ceased after a maternal elimination diet for cow's milk. ...
Hallberg B - - 2013
Seizures during the neonatal period are always medical emergencies. Apart from the need for rapid anticonvulsive treatment, the underlying condition is often not immediately obvious. In the search for the correct diagnosis, a thorough history, clinical examination, laboratory work-up, neurophysiological and neuroradiological investigations are all essential. A close collaboration between ...
Saraswathy T S - - 2013
Rubella infection in pregnant women during the first trimester of pregnancy can lead to fetal anomalies, commonly known as congenital rubella syndrome (CRS). The objective of our study was to analyze the serological test results among infants suspected of having CRS aged < or = 12 months compared with their ...
Cacace María L - - 2013
Abstract Brucellosis has been reported mainly among pregnant women, and it may lead to spontaneous abortion, intrauterine fetal death, or delivery of an infected neonate. Transmission through breast milk has also been described, but congenital cases are not commonly reported. We present the clinical findings, laboratory studies, treatment, and final ...
Ceballos F C - - 2013
The European royal dynasties of the Early Modern Age provide a useful framework for human inbreeding research. In this article, consanguineous marriage, inbreeding depression and the purging of deleterious alleles within a consanguineous population are investigated in the Habsburgs, a royal dynasty with a long history of consanguinity over generations. ...
Cesur Y Y Department of Pediatric Endocrinology, Yiiziincii Yil University, Faculty of Medicine, Van, - - 2013
Hypocalcaemia evaluation of the clinical, biochemical and radiologicalfeatures of 91 infants with rickets who presented as hypocalcaemic convulsions. Ninety-one hypocalcaemic infants who were brought to hospital with convulsion and diag-nosed with rickets related to vitamin D deficiency according to their clinical, biochemical and radio-logicalfeatures were retrospectively reviewed. Mean values of ...
Stankiewicz Barbara - - 2013
BACKGROUND: Conventional endotracheal pediatric tubes offer high resistance due to their small diameters and relatively high flow during ventilation. Any increase of the diameter of the tube lumen decreases the airway resistance and subsequently, the work of breathing (WOB). We compared ventilation mechanics using a new, cone-shaped endotracheal tube of ...
Peterson Julie A JA Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI 53226-3548, US. - - 2013
Neonatal alloimmune thrombocytopenia, (NAIT) is caused by maternal antibodies raised against alloantigens carried on fetal platelets. Although many cases are mild, NAIT is a significant cause of morbidity and mortality in newborns and is the most common cause of intracranial haemorrhage in full-term infants. In this report, we review the ...
Klein Richard H - - 2013
To determine the relationship between the activated partial thromboplastin time (aPTT) measured with a standard laboratory assay and the aPTT measured with a bedside device in infants on heparin therapy after cardiothoracic surgery. Twenty infants aged below 1 year who were on heparin therapy were included. Exclusion criteria were prematurity, ...
Wang G H GH Department of Pediatrics, First Hospital ofJilin University, Changchun, - - 2013
To assess the tissues and organs commonly involved and the clinical features in the invasive fungal infection (IFI) of Candida albicans in the preterm infants. Eight preterm infants who developed IFI with positive blood culture for Candida albicans were retrospectively studied. All infants received selected clinical and laboratory parameters evaluation, ...
Perone Sammy S Department of Psychology and Delta Center, University of Iowa Iowa City, IA, - - 2013
What motivates children to radically transform themselves during early development? We addressed this question in the domain of infant visual exploration. Over the first year, infants' exploration shifts from familiarity to novelty seeking. This shift is delayed in preterm relative to term infants and is stable within individuals over the ...
Heaton Alexandra E AE School of Paediatrics and Child Health, University of Western Australia Perth, WA, - - 2013
The proposal that dietary docosahexaenoic acid (DHA) enhances neurocognitive functioning in term infants is controversial. Theoretical evidence, laboratory research and human epidemiological studies have convincingly demonstrated that DHA deficiency can negatively impact neurocognitive development. However, the results from randomized controlled trials (RCTs) of DHA supplementation in human term-born infants have ...
Alemán Inmaculada - - 2012
The objective of this study is to present the characteristics of a collection of identified infants and young children housed in the Laboratory of Anthropology of the University of Granada, Spain. The sample, which is still being enlarged, is currently composed of 230 complete skeletons aged from 5 months of ...
Jung Young Hwa - - 2012
OBJECTIVE:: To evaluate clinical applicability of noninvasive hemoglobin (Hb) measurement with a pulse CO-oximeter in neonates. DESIGN:: Prospective comparison study. SETTING:: Neonatal ICU. PATIENTS:: Fifty-six preterm and term infants with median age = 20 days (range = 1-98 days) and median weight = 1,440 g (range = 530-4,230 g). INTERVENTIONS:: ...
Flidel-Rimon Orna - - 2012
Guidelines for detection of early neonatal sepsis employ a risk factor approach combined with laboratory parameters. In an era of increasing intrapartum antibiotic prophylaxis (IAP), we re-assessed the approach as a whole and each of the risk factors individually. This retrospective study included infants with risk factors for sepsis or ...
Kim Ansoon - - 2012
Simple and rapid detection of trace amounts of melamine in milk products has been achieved with a portable sensor system based on surface-enhanced Raman scattering (SERS). The sensor system comprised high performance gold nanofinger SERS sensor chips and a custom-built prototype portable Raman spectrometer. Compared to the FDA procedure and ...
Rosebraugh Matthew R MR College of Pharmacy and College of Medicine, University of Iowa, Iowa City, Iowa 52242, - - 2013
Very preterm infants commonly develop anemia requiring multiple red blood cell transfusions (RBCTx). This is in part attributable to heavy laboratory phlebotomy loss. Quantification of the extent to which laboratory blood loss contributes to anemia sufficient to prompt RBCTx has not been examined. Twenty-six preterm infants weighing less than 1500 ...
Majumdar Subeer S - - 2012
In humans, as well as in other higher primates, the infantile testis is exposed to an adult-like hormonal milieu, but spermatogenesis is not initiated at this stage of primate development. In the present study, we examined the molecular basis of this intriguing infertile state of the primate testis. The integrity ...
Read Jennifer S - - 2012
Infant laboratory abnormalities have been associated with exposure to antiretrovirals and to trimethoprim/sulfamethoxazole (TMP/SMX). We analyzed data from International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT) Protocol P1025, a prospective cohort study of human immunodeficiency virus type 1 (HIV)-infected women and their infants. Live-born, singleton, HIV-uninfected infants with at ...
Mozafari Kermani Ramin - - 2012
Many studies show that congenital defects in infants conceived by assisted reproductive techniques (ART) are more than infants of normal conception (NC). The aim of this study is to determine the frequency of congenital anomalies in ART infants from Royan Institute and to compare congenital anomalies between two ART techniques.  ...
Kicker Jennifer S - - 2012
A former 34-week-old female infant with Down syndrome underwent surgical correction of a congenital heart defect at 5 months of age. Her postoperative course was complicated by severe pulmonary hypertension and junctional ectopic tachycardia. Following treatment with amiodarone infusion, she developed laboratory indices of acute liver injury. At their peak, ...
Hoefer Dina - - 2012
Introduction. Surveillance for laboratory-confirmed influenza-associated deaths in children is used to monitor the severity of influenza at the population level and to inform influenza prevention and control policies. The goal of this study was to better estimate pediatric influenza mortality in New York state (NYS). Methods. Death certificate data were ...
Arboleya Silvia - - 2011
Microbial colonization of the infant gut is essential for the development of the intestine and the immune system. The profile of intestinal microbiota in the full-term, vaginally delivered, breast-fed infant is considered as ideally healthy. However, in preterm infants this process is challenging, mainly due to organ immaturity, antibiotics use ...
Kiyohara Masashi - - 2012
Bifidobacteria inhabit the lower intestine of mammals including humans where the mucin gel layer forms a space for commensal bacteria. We previously identified that infant-associated bifidobacteria possess an extracellular membrane-bound endo-α-N-acetylgalactosaminidase (EngBF) that may be involved in degradation and assimilation of mucin-type oligosaccharides. However, EngBF is highly specific for core-1-type ...
Marcobal Angela A Department of Microbiology and Immunology, Stanford School of Medicine, CA 94305, - - 2011
Newborns are colonized with an intestinal microbiota shortly after birth, but the factors governing the retention and abundance of specific microbial lineages are unknown. Nursing infants consume human milk oligosaccharides (HMOs) that pass undigested to the distal gut, where they may be digested by microbes. We determined that the prominent ...
Makino Hiroshi - - 2011
The gastrointestinal tracts of neonates are colonized by bacteria immediately after birth. It has been discussed that the intestinal microbiota of neonates includes strains transferred from the mothers. Although some studies have indicated possible bacterial transfer from the mother to the newborn, this is the first report confirming the transfer ...
Singh Rupa Dalmia - - 2011
Torsion of the testis is a true surgical emergency in paediatric age group. Prompt recognition of the condition and immediate surgical intervention is the only hope for testicular salvage. The condition becomes all the more important when this occurs in an undescended testis as the diagnosis is often delayed, and ...
Chang Ju Young - - 2011
OBJECTIVES:: To investigate the previously unexplored diversity of neonatal intestinal microbiota and monitor early intestinal colonization patterns in Korean preterm infants using high-throughput pyrosequencing technology combined with 16S rDNA- based molecular methods METHODS:: A total of 46,369 partial 16S rDNA sequences obtained from 30 fecal samples serially taken from 10 ...
Mantan M - - 2011
Megacystis, microcolon, intestinal hypoperistalsis is an uncommon condition presenting in neonatal age with features of intestinal obstruction and bladder evacuation abnormalities. We present here an infant girl with the diagnosis consistent with this entity.
Olusanya Bolajoko O - - 2011
We explored factors associated with traditional maternity/herbal homes (TMHs) run by traditional birth attendants (TBAs) compared with hospital or home delivery in Lagos, Nigeria, and found that infants delivered at TMHs were less likely to have severe hyperbilirubinemia compared with infants delivered in hospitals or residential homes. These infants were ...
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