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Alaattin Unsal
This aim of study was to determine the prevalence of anemia among infants from 4 to 11 months age and also to evaluate possible related risk factors with anemia. Hemoglobin level was determined by Hemocue hemoglobinometer in capillary blood samples. Anemia was diagnosed if hemoglobin (Hb) concentration was < 11.0 ...
Leblanc Caroline P - - 2007
PURPOSE: Iron deficiency anemia (IDA) during pregnancy and infancy is still common in developed countries, especially in low-income groups. We examined the prevalence of anemia and IDA in healthy low-income pregnant women participating in the Early Childhood Initiatives (ECI) program, and in their infants when they reached six months of ...
Vendt Neve - - 2007
BACKGROUND: The number of different laboratory tests and reference values are used to diagnose iron deficiency, but there is no agreement regarding the diagnostic criteria for infants. Aim of study. To establish reference values for serum ferritin, mean cell volume, and hemoglobin in infants aged from 9 to 12 months ...
Pulis Svetlana - - 2007
Hb F-Malta-I [Ggamma117(19)His-->Arg, CAT-->CGT] is a stable and benign variant of Hb F found in 1.8% of Maltese newborn. We studied 120 Hb F-Malta-I heterozygotes and four Hb F-Malta-I homozygotes. The mean proportion of Ggamma-F-Malta-I in Hb F was 0.26 +/- 0.03 for the Hb F-Malta-I heterozygotes and 0.58 +/- ...
Vendt Neve - - 2007
OBJECTIVE: To investigate the prevalence and causes of iron deficiency anemia in infants aged 9 to 12 months in Estonia. MATERIAL AND METHODS: Every second child aged 9-12 months was randomly selected from primary medical centers in seven counties from all over Estonia. A questionnaire concerning eating habits and lifestyle ...
Agostoni Carlo - - 2007
The complementary feeding period is a critical stage for growth and development. Infants in developing countries and selected individuals in developed countries may benefit from micronutrient supplementation, but long-term effects are still poorly explored. We have some evidence, coming from observational studies, of the role of iron in the second ...
Siddappa Ashajyothi M AM Division of Neonatology, Hennepin County Medical Center, Department of Pediatrics, University of Minnesota School of Medicine, Minneapolis, Minn., - - 2007
Serum ferritin measurements are used in clinical populations to estimate total body iron stores and the risk of subsequent iron deficiency or overload. The lack of normative newborn serum ferritin concentration data between 23 and 41 weeks has led to difficulty in establishing the incidence and degree of abnormal iron ...
Li Xin - - 2007
Borrelia burgdorferi survives in an enzootic cycle, and Dps proteins protect DNA against damage during starvation or oxidative stress. The role of a Dps homologue encoded by Borrelia in spirochaete survival was assessed. Dps-deficient spirochaetes were infectious in mice via needle-inoculation at the dose of 10(5) spirochaetes. Larval ticks successfully ...
Rao Raghavendra R Division of Neonatology, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA. - - 2007
Both iron deficiency and iron excess during the fetal and neonatal period bode poorly for developing organ systems. Maternal conditions such as iron deficiency, diabetes mellitus, hypertension and smoking, and preterm birth are the common causes of perinatal iron deficiency. Long-term neurodevelopmental impairments and predisposition to future iron deficiency that ...
Lozoff Betsy B Center for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109-0406, USA. - - 2006
Infants aged 6-24 mo are at high risk of iron deficiency. Numerous studies worldwide have sought to identify predictors of iron deficiency in this age group. The objectives of the study were to apply a physiologic model to identify risk factors for iron deficiency and to consider those risk factors ...
Mayer Chad W - - 2006
Neutrophil dysfunction can result from oxidative burst defect or from glucose-6-phosphate dehydrogenase (G6PD) deficiency; we noted both in the same patient. A 4-month-old male infant with G6PD deficiency presented with swelling of the left middle finger, left leg, and right big toe. At 5 weeks of age he was hospitalized ...
Hambidge K Michael - - 2006
Zinc (Zn) nutrition is of special practical importance in infants and young children, however relatively little is known about maturation and comparative aspects of Zn absorption. The principal objective of this paper is to compare Zn absorption of term infants, preterm infants, and adults on low phytate diets. Existing data ...
Ruz Manuel - - 2006
PURPOSE OF REVIEW: To analyse information about the effects of zinc supplementation on the growth of infants and children, and also the effects of maternal supplementation. RECENT FINDINGS: Two (of 12) studies have recently reported significant weight increments in the zinc supplemented group, and only one study found positive effects ...
Lozoff Betsy B Center for Human Growth and Development, and Department of Pediatrics and Communicable Diseases, University of Michigan, 300 N. Ingalls, Ann Arbor, MI 48109, USA. - - 2006
To assess change in cognitive functioning after iron deficiency in infancy, depending on socioeconomic status (SES; middle vs low). Longitudinal study. Urban community in Costa Rica (infancy phase [July 26, 1983, through February 28, 1985] through 19-year follow-up [March 19, 2000, through November 4, 2002]). A total of 185 individuals ...
Ovali F - - 2006
OBJECTIVE: To evaluate the effects of addition of human milk (HM) fortifier and iron on the anti-infective properties of HM. STUDY DESIGN: HM samples were collected from 28 lactating mothers who delivered prematurely, within the first week of post-natal life. HM fortifier Eoprotin was used. The effects of this fortifier ...
Khambalia Amina - - 2006
The purpose of this study was to examine whether maternal iron and/or folate status influences human milk folate secretion and is responsible for growth faltering of Otomi infants in Capulhuac, Mexico. Breast-feeding mothers (n = 71) were randomized at 22 +/- 13 d (baseline) postpartum to receive a daily multivitamin ...
Larocque Renée - - 2006
OBJECTIVE: To assess the effect on birthweight of antenatal mebendazole plus iron vs. placebo plus iron in a highly hookworm-endemic area. METHODS: Double-blind, randomized controlled trial set in rural and peri-urban communities in the Peruvian Amazon region. A total of 1042 second trimester pregnant women between the ages of 18 ...
Baykan Ali - - 2006
Iron deficiency anemia (IDA) causes growth and developmental retardation in infants. Iron supplementation from the 4th month of age may prevent IDA, but side effects of oral iron supplementation limit its usage. The aim of this study was to investigate the effect of maternal iron supplementation on the iron status ...
Kienast Antonia - - 2007
We report ten infants (mean gestational age: 30 weeks; range: 25 to 40 weeks) with zinc deficiency dermatitis who developed erosive, impetiginized periorificial dermatitis at 10 weeks of age (corresponding to a mean gestational age of 41.4 weeks, with a range of 36-44 weeks), but who were otherwise well. Cutaneous ...
Lozoff Betsy - - 2006
Iron deficiency (ID) is common in pregnant women and infants worldwide. Rodent models show that ID during gestation/lactation alters neurometabolism, neurotransmitters, myelination, and gene/protein profiles before and after iron repletion at weaning. Human infants with iron deficiency anemia test lower in cognitive, motor, social-emotional, and neurophysiologic development than comparison group ...
Wasantwisut Emorn - - 2006
Iron deficiency is prevalent in children and infants worldwide. Zinc deficiency may be prevalent, but data are lacking. Both iron and zinc deficiency negatively affect growth and psychomotor development. Combined iron and zinc supplementation might be beneficial, but the potential interactions need to be verified. In a randomized, placebo-controlled trial ...
Hicks Penni D - - 2006
Iron absorption in adults is regulated by homeostatic mechanisms that decrease absorption when iron status is high. There are few data, however, regarding the existence of a similar homeostatic regulation in infants. We studied 2 groups of human milk-fed infants using (57)Fe (given as ferrous sulfate without any milk) and ...
Lubach Gabriele R - - 2006
Iron deficiency is the most common micronutrient deficiency during pregnancy, and maternal anemia has been associated with poor pregnancy outcomes. However, it is still not clear how directly maternal iron status is linked to the infant's iron status postpartum. We investigated the impact of maternal iron deficiency on the hematological ...
Tarasev Michael M Department of Biological Chemistry, University of Michigan, 1301 Catherine Street, Ann Arbor, Michigan 48109-0606, - - 2006
Phthalate dioxygenase (PDO) and its reductase are parts of a two-component Rieske dioxygenase system that initiates the aerobic breakdown of phthalate by forming cis-4,5-dihydro-4,5-dihydroxyphthalate (DHD). Aspartate D178 in PDO, located near its ferrous mononuclear center, is highly conserved among Rieske dioxygenases. The analogous aspartate has been implicated in electron transfer ...
Meyerovitch Joseph - - 2006
OBJECTIVES: The purpose of this work was to use the comprehensive computerized database of Clalit Health Services to analyze the prevalence and contributing factors of anemia among the population of Clalit Health Services-insured Israeli infants aged 9 to 18 months, characterized by ethnic sector. METHODS: This was a cross-sectional retrospective ...
Sichieri Rosely - - 2006
OBJECTIVE: To assess the association between iron status at birth and growth of preterm infants. METHODS: Ninety-five premature babies (26 to 36 weeks of gestational age) born from July 2000 to May 2001 in a public hospital in Rio de Janeiro, Southeastern Brazil, were followed up for six months, corrected ...
Pohlandt Frank - - 2006
To discuss the viewpoint article "How much glutamate is toxic in paediatric parenteral nutrition?" Acta Paediatr 2005;94;16-9. There is no doubt that glutamate used at high bolus doses in animal experiments would permanently damage brain cells. However, these effects should not be extrapolated to the condition of parenteral nutrition of ...
Bhargava Sital - - 2006
Infants and toddlers with suspected iron-deficiency anemia should begin treatment with oral ferrous sulfate (3 mg/kg/d of elemental iron). A rise in hemoglobin >1 g/dL after 4 weeks supports the diagnosis of iron deficiency, and supplementation should continue for 2 additional months to replenish iron stores. Recheck hemoglobin at the ...
Whitehead V Michael - - 2006
Cobalamin deficiency in the newborn usually results from cobalamin deficiency in the mother. Megaloblastic anaemia, pancytopenia and failure to thrive can be present, accompanied by neurological deficits if the diagnosis is delayed. Most cases of spina bifida and other neural tube defects result from maternal folate and/or cobalamin insufficiency in ...
Widness John A - - 2006
Because critically ill premature infants experience significant iron loss due to phlebotomy and have high iron needs for growth, Fe absorption and incorporation studies are clinically important. A prospective, controlled, randomized, open 21-d study was conducted in infants with birth weight <1300 g and gestational age < 31 wk to ...
Chaparro Camila M - - 2006
BACKGROUND: Delayed clamping of the umbilical cord increases the infant's iron endowment at birth and haemoglobin concentration at 2 months of age. We aimed to assess whether a 2-minute delay in the clamping of the umbilical cord of normal-weight, full-term infants improved iron and haematological status up to 6 months ...
Kayodé A P Polycarpe - - 2006
The purpose of this study was to improve the micronutrient quality of indigenous African infant flour using traditional techniques available in the region. Response surface methodology was used to study the effect of duration of soaking, germination, and fermentation on phytate and phenolic compounds (PC), pH, viscosity, and the in ...
Kaur Deepinder - - 2007
Iron elevation is well-documented in the Parkinsonian midbrain but its cause and contribution to subsequent neurodegeneration remain unknown. Mice administered iron at doses equivalent to those found in iron-fortified human infant formula during a developmental period equivalent to the first human year of life display progressive midbrain neurodegeneration and enhanced ...
Lozoff Betsy B Center for Human Growth and Development and the Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor 48109, USA. - - 2006
Infants are at high risk for iron deficiency and iron-deficiency anemia. This review summarizes evidence of long-term effects of iron deficiency in infancy. Follow-up studies from preschool age to adolescence report poorer cognitive, motor, and social-emotional function, as well as persisting neurophysiologic differences. Research in animal models points to mechanisms ...
Lee H S HS Department of Sports Science, Seoul Sports Graduate University, Seoul, - - 2006
The purpose of this study was to assess the prevalence of iron deficiency anemia among Korean pregnant women and to assess the association between maternal hemoglobin (Hb) level and pregnancy outcome. A longitudinal study. Ewha Womans University Hospital, Seoul, Korea. A total of 248 normal pregnant women of 24-28 weeks ...
Durkan Anne M - - 2006
Darbepoetin is a newer analogue of epoetin, with a longer half-life, that allows less frequent administration. There are currently no published data available for its use in infants. We report our experience with this drug in infants with chronic renal impairment, weighing less than 8 kg. Infants had baseline haemoglobin ...
Shashiraj - - 2006
OBJECTIVE: Exclusive breastfeeding is recommended till 6 months age. Factors regulating the breastmilk iron and lactoferrin levels are incompletely known. Considering high prevalence of nutritional anemia in lactating mothers, we studied the iron status of lactating mothers, their breastmilk iron and lactoferrin levels to determine any relationship between them. DESIGN: ...
Verrall Tanya - - 2006
OBJECTIVES: To evaluate innovative communication strategies promoting iron nutrition for infants at risk for iron deficiency anemia (IDA) in a northern Aboriginal community. STUDY DESIGN: A prospective process evaluation. METHODS: A social marketing approach was used in the development, implementation and evaluation of the communication strategies. A post-intervention questionnaire was ...
Krebs Nancy F - - 2006
OBJECTIVE: This study was undertaken to assess the feasibility and effects of consuming either meat or iron-fortified infant cereal as the first complementary food. METHODS: Eighty-eight exclusively breastfed infants were enrolled at 4 months of age and randomized to receive either pureed beef or iron-fortified infant cereal as the first ...
Meinzen-Derr Jareen K - - 2006
The WHO recommends exclusive breast-feeding (EBF) for the first 6 mo of life to decrease the burden of infectious disease. However, some are concerned about the effect of EBF >6 mo on iron status of children in developing countries in which anemia is prevalent. This study examines the risk of ...
Parsons S D C - - 2006
Neonatal, poikilocytic anaemia in some members of the Hippotragini has previously been documented but not fully investigated. This study was undertaken to describe the erythrocyte morphology of roan antelopes (Hippotragus equinus) during the first 4 weeks after birth and to identify aspects of haemoglobin (Hb) production that might be implicated ...
Rioux France M - - 2006
Marginal intake of iron and omega-3 long-chain fatty acids (DHA) is prevalent among pregnant women. It is not clear to what extent poor iron or DHA status during pregnancy impacts on an infant's functional outcomes. A few studies suggest that inadequate maternal iron or DHA status may be associated with ...
Dewey Kathryn G - - 2006
In 2001, a WHO Expert Consultation concluded that waiting until 6 months to introduce complementary foods to breastfed infants confers several benefits for both infants and mothers. Nonetheless, there is still controversy about this issue. In developing countries, the reduced risk of infant gastrointestinal illness and increased duration of maternal ...
Miller Susan M - - 2006
OBJECTIVES: To test the utility of zinc protoporphyrin to heme ratio (ZnPP/H) as an indicator of iron status in premature infants and to evaluate the effect of oral iron supplements on oxidative injury. We hypothesized that iron sulfate supplementation would decrease the ZnPP/H in preterm infants. STUDY DESIGN: Infants eligible ...
Zaida F - - 2006
BACKGROUND/AIMS: Iron deficiency impairs growth and psychomotor development of infants. In Morocco, infusions are introduced very early in infant diet, and could contribute to iron deficiency, due to their high polyphenol content. METHODS: The availability of tea, mint and vervain infusions was assessed using an in vitro model of digestion ...
Sharieff Waseem - - 2006
This paper models the effects of a home-fortification program (using Sprinkles which contain zinc and iron and other micronutrients), in Pakistan, a country with high levels of infant mortality, anemia, and diarrhea. It uses the results of randomized trials of the effect of Sprinkles on anemia and on longitudinal prevalence ...
Golub Mari S MS Department of Environmental Toxicology, CNRPC, Room 1925, University of California, Davis, One Shields Avenue, Davis, CA 95616, United States. - - 2006
Human studies have shown that iron deficiency and iron deficiency anemia in infants are associated with behavioral impairment, but the periods of brain development most susceptible to iron deficiency have not been established. In the present study, rhesus monkeys were deprived of iron by dietary iron restriction during prenatal (n=14, ...
Landahl Göran - - 2005
The objective of the study was to determine the prevalence of iron deficiency and iron deficiency anemia among elite women soccer players. Hemoglobin, serum iron, serum total iron binding capacity, and ferritin were determined in 28 female soccer players called up for the national team. Of the investigated female soccer ...
Faber Mieke - - 2005
BACKGROUND: Maize-meal porridge is used for infant feeding in many African countries, including South Africa. A low-cost, finely milled, maize-meal porridge was fortified with beta-carotene, iron, and zinc (100% of recommended dietary allowance), as well as ascorbic acid, copper, selenium, riboflavin, vitamin B-6, vitamin B-12, and vitamin E. OBJECTIVE: We ...
Türker Gülcan - - 2005
Premature infants<1500 g were randomly assigned to study and control groups. In the study group, 42 premature infants received recombinant human erythropoietin (r-Hu EPO) 750 U/kg per week subcutaneously from day 5 to 40 and enteral iron supplementation of 2 to 6 mg/kg/d beginning on day 14 provided that they ...
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