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Results 501 - 550 of 946
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Friel J K - - 1998
BACKGROUND: Zinc and iron may share common pathways for absorption and compete for uptake into mucosal cells. We determined whether elevated ratios of zinc to iron would interfere with erythrocyte incorporation of iron in premature infants both during and between feeds. METHODS: In the first experiment, five premature infants (<2500 ...
Roncagliolo M - - 1998
Iron deficiency anemia has long been thought to have effects on the central nervous system (CNS). Finding direct evidence of this in human infants, however, has been challenging. Auditory brainstem responses (ABRs) provide a noninvasive means of examining an aspect of the CNS that is rapidly maturing during the age ...
Haram-Mourabet S - - 1998
OBJECTIVES: We hypothesized that the concentration of major essential mineral elements in meconium correlate with gestational age (GA) or birth weight. To verify this premise we determined the concentration in meconium of calcium, magnesium, phosphorus, copper, zinc, iron, and manganese. METHODS: Thirty-four appropriate for age singleton infants without major congenital ...
Persson L A - - 1998
We analysed whether 12-month-old Swedish infants who have been fed iron-fortified and relatively zinc-rich foods, according to current recommendations, have adequate iron and zinc status. A cohort of 76 healthy, full term Swedish infants was followed regarding feeding habits and growth from birth to 12 months of age, when haemoglobin, ...
Engelmann M D - - 1998
During weaning the infant has a high iron requirement, and highly available dietary iron is needed to ensure optimal iron status. Muscle tissue has been identified as an enhancer of nonheme iron absorption in adults, although the influence of meat on nonheme iron absorption in infants has not been previously ...
Freeman V E - - 1998
OBJECTIVES: To assess iron status in a sample of clinically well, Caucasian children and explore the complex factors which contribute to iron deficiency during infancy. DESIGN: Infants recruited at birth and followed longitudinally at 1, 2, 3, 4, 5, 6, 9, 12, 24 and 36 months; feeding practices and socioeconomic ...
Dewey K G - - 1998
To evaluate the effect of introducing complementary foods before 6 mo of age, we randomly assigned 164 infants who had been exclusively breast-fed for 4 mo to continue being exclusively breast-fed until 6 mo (EBF group) or to receive iron-fortified foods in addition to breast milk from 4 to 6 ...
Lönnerdal B - - 1998
Full-term human infants are believed to possess adequate copper stores to last through weaning regardless of the copper content of the diet they are fed. This may not be generally true, however; a combination of low copper intake and low bioavailability from the diet may lead to copper deficiency. More ...
Walter T - - 1998
OBJECTIVES: For bottle-fed babies or nursing infants who receive milk supplements, the American Academy of Pediatrics recommends the use of iron-fortified infant formula. Because these recommendations have not been universally adopted, the hematologic effects of currently available low-iron formulas need to be determined. STUDY DESIGN: Healthy Chilean 6-month-old infants (without ...
Choi Y S - - 1998
BACKGROUND: Screens for anemia are among the most commonly done laboratory tests in children. The red cell distribution width (RDW) has been proposed as a diagnostic aid in the evaluation of pediatric anemias, but no prospective studies have been published describing its use. METHODS: A screening hematocrit determination done at ...
Olson R J - - 1998
INTRODUCTION: Monocular elevation deficiency is characterized by unilateral limitation of elevation in both adduction and abduction and is usually present at birth. Dissociative phenomena such as dissociated vertical deviation are well recognized in association with conditions such as congenital esotropia but much less so in association with conditions such as ...
Fellman V - - 1998
BACKGROUND: Several cases of a distinctive lethal neonatal disorder have been found in the Children's Hospital, Helsinki, Finland. However, the combination of presenting features is not typical of any known metabolic disease. We have analysed all known cases of this disorder in the hospital since 1965 and in Finland since ...
Lozoff B - - 1998
This study tested the hypothesis that infants with iron-deficiency anemia show behaviors, such as increased proximity to caregivers, increased wariness or hesitance, and decreased activity, that could contribute to "functional isolation." The behavior of 52 Costa Rican 12- to 23-month-old infants with iron-deficiency anemia was contrasted with that of 139 ...
Lifschitz C H - - 1998
BACKGROUND: The effect of adding rice cereal to formula on calcium and iron bioavailability was studied. METHODS: Fourteen healthy infants were studied at 2-week intervals to assess the absorption of calcium and iron from formula or formula mixed with rice cereal. Infants were randomly assigned to initiate the study either ...
Glahn R P - - 1998
We have applied an in vitro digestion/Caco-2 cell culture model to the assessment of iron availability from human milk and a generic cow's milk-based infant formula. Experiments were designed to determine the availability of iron from human milk relative to infant formula and whether known promoters of iron absorption would ...
Pang S - - 1998
Severe 3beta-hydroxysteroid dehydrogenase (3beta-HSD) deficiency in the adrenals and gonads is a well known cause of salt-wasting and non-salt-wasting forms of congenital adrenal hyperplasia (CAH), male pseudohermaphroditism and mild androgen excess symptoms in children and older females. A mild spectrum of Delta5 steroid abnormality in young children with premature pubarche ...
Sawchuk P - - 1998
Iron-deficiency anemia (IDA) has received relatively little attention in Canada, with no national public health initiatives even among high-risk infants. IDA has a high prevalence in First Nations children and has been shown to cause developmental delay. This study is a before/after prevalence survey studying the effect of a public ...
Galanello R - - 1998
In this paper we report a male infant heterozygous for thalassemia with a mild glucose 6 phosphate dehydrogenase deficiency. The molecular basis of this new Class III G6PD variant is a G-->T mutation at nucleotide 34 in the exon 2, which predicts a Val-->Leu aminoacid substitution at codon 12. We ...
Buonocore G - - 1998
Heparinized blood samples were obtained at birth from 164 newborn infants (101 full term; 63 preterm). Intra-erythrocyte free iron concentration and hypoxanthine plasma levels were determined by high-pressure liquid chromatography. Intra-erythrocyte free iron concentration was higher in preterm than in full term babies (p < 0.0001) and adults (p < ...
Kuiper-Kramer E P - - 1998
The concentration of soluble transferrin receptors in serum has proven to be a reliable predictor of iron status in adults. Its high sensitivity for iron deficiency combined with a small sample size (10 microliters) makes it an interesting parameter for the assessment of iron stores in newborn infants. In the ...
Hodgins S - - 1998
PURPOSE: This paper documents the problem of iron-deficiency anemia in the Inuit region of Nunavik, in Northern Quebec, particularly among pregnant women and infants. It also addresses the issue of Helicobacter pylori gastritis as a possible cause of anemia in this population. METHOD: Data on anemia in pregnancy are from ...
Sanchez-Andres J V - - 1997
The evolution of vesicular zinc-containing boutons in the developing rabbit hippocampus has been studied during early postnatal life using the selenite-Danscher histochemical method. By P3, large immature mossy fiber boutons with labeled synaptic vesicles were seen in the hilus of the dentate gyrus and in the stratum lucidum of the ...
Preziosi P - - 1997
We studied the effect of iron supplementation on the iron status of mothers and on biochemical iron status and clinical and anthropometric measures in their infants. The subjects were 197 pregnant women selected at 28 wk +/- 21 d of gestation at a mother-and-child health center in Niamey, Niger. Ninety-nine ...
Aslan Y - - 1997
We compared the absorption of iron from grape molasses (GM) and ferrous sulfate (FS) using the post-absorptive serum iron increase method (non-radioactive). The study involved 56 subjects, aged 6-36 months. Group I consisted of 30 subjects with iron deficiency anemia (IDA) and group II, 26 non-anemic subjects. Each group was ...
Inder T E - - 1997
To explore the hypothesis that excessive iron loads may increase the formation of free radicals and the development of retinopathy of prematurity in preterm infants, we carried out a prospective observational study of the association between transfusion volume, iron status, and retinopathy.
Menendez C - - 1997
BACKGROUND: Malaria and anaemia, especially that due to iron deficiency, are two leading causes of morbidity worldwide. Little is known about the relative contribution of Plasmodium falciparum infection and iron deficiency to the aetiology of anaemia in malaria-endemic areas. We undertook a randomised comparison of different strategies for control of ...
Kapil U U Department of Human Nutrition, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, - - 1997
For the last 40 years the Kullu district in Himachal Pradesh, India, has been recognised as an area of endemic iodine deficiency. The state government has adopted a policy of universal iodisation of salt since 1984. The iodine status of pregnant mothers is an indicator of the community status of ...
Yeung G S - - 1997
To establish percentile estimates of transferrin receptor (TfR) for healthy infants, plasma TfR was measured in 485 healthy infants 9-15 mo of age from Edmonton, Toronto, Montreal, and Halifax. Education and income of the sample families were reflective of the average family based on the 1991 census estimates. The mean ...
Wharf S G - - 1997
OBJECTIVES: To determine the effects of dietary, physiological or environmental factors on body iron levels in infants aged 4-18 months. DESIGN: The daily iron intake of the infants was measured from a diet history obtained by interview using a standardised question sheet, previously validated against weighed intake (minimum 3 days) ...
Msolla M J - - 1997
Anaemia is a very common condition during pregnancy. This is particularly so in developing countries where the level of intake of iron rich foods is low; malaria and other intestinal parasites are common. This study was conducted to determine the prevalence of anaemia and the type of anaemia existing in ...
Bentley M E - - 1997
Zinc deficiency has been associated with growth deficits, reduced dietary intake and appetite, and has been hypothesized to result in reduced activity. This randomized, double-blind, placebo-controlled study examined whether 10 mg of oral zinc as zinc sulfate, given daily for up to 7 mo, affected activity patterns of 85 Guatemalan ...
Shalev H - - 1997
Congenital dyserythropoietic anemia type I is a rare inherited bone marrow disorder characterised by macrocytic anemia with pathognomonic morphological ultrastructural features in erythroid precursors. The disease is usually not diagnosed in the neonatal period. In a retrospective study of 31 patients we found that 17 were first seen in the ...
Gill D G - - 1997
Six-month-old infants were recruited at 21 centres in the UK and Ireland and randomly assigned to receive matching iron-fortified (12.3 mg/l iron) or non-fortified (1.4 mg/l iron) formula for 9 months. Infants already receiving cow's milk continued this feed. Haematological indices and iron status were evaluated at age 6 months, ...
Riveros-Rosas H - - 1997
Personal exposures to various metals in airborne particulates in Mexico City were measured over a seven consecutive-day period. Subjects were divided into two groups, Group A, whose work required them to spend considerable time outdoors and in traffic (messengers, delivery men, taxi drivers, salesmen), and Group B who spent most ...
Friel J K - - 1997
The objective of this prospective, cohort study was to compare the nutritional status of full-term infants who were fed human milk (BF, n = 29), formula (FF, n = 30) or evaporated milk formulae (EM, n = 30) for at least 3 months. Infants were seen at enrollment, 3 and ...
Singla P N - - 1997
The effect of maternal iron deficiency anemia on fetal growth was studied in 54 anaemic (haemoglobin < 11.0 g/dl) mothers. Twenty-two mothers served as controls (haemoglobin > or = 11.0 g/dl). All the women had singleton live births at term gestation. The maternal iron status was assessed by serum ferritin ...
Squires L - - 1997
Holocarboxylase synthetase deficiency is typically a biotin responsive disorder that presents with lactic acidosis, tachypnea, temperature instability, and shock in neonates (Briones et al.1989 and Fuchshuber et al. 1992). The primary defect in cases studied to date appears to be the decreased affinity of HCS for its substrate, biotin (Gompertz ...
Dalton M A - - 1997
One objective of this clinical trial was to determine whether calcium and phosphorus supplementation of infant formula affects the iron status of healthy full-term infants. One hundred three infants were randomly assigned to receive iron-fortified, cow milk-based infant formula (465 mg Ca and 317 mg P/L) or the same formula ...
Airede A I - - 1997
Zinc(Zn) remains an important micronutrient needed by the growing foetus and newborn. We are unaware of a previous study delineating the longitudinal evolution in the African fullterm (FT) infant. Hence we prospectively studied thirty randomly selected stable FT infants (M:F; 17:13) born between July 1991 and April, 1992. Serum Zn ...
Myint-Oo - - 1997
Influx of the purine nucleoside, adenosine, was assessed in erythrocytes from both normal subjects and from subjects with a range of genetically determined erythrocyte disorders from Myanmar. The latter included alpha-thalassemia major (Myanmar variant), beta-thalassemia major (Myanmar variant), beta-thalassemia trait, HbEE and HbAE erythrocytes and two variants of glucose-6-phosphate dehydrogenase ...
Scariati P D - - 1997
BACKGROUND: Concern has been raised by infant feeding experts that supplementing breastfed infants with iron-fortified formula rather than low-iron formula may have an undesirable impact on their gastrointestinal flora. Thus far, there have been no clinical studies to address this issue directly. We compared the reported frequency of diarrhea for ...
Salmenperä L - - 1997
This article reviews situations in which we should be alert to the risk of trace element deficiencies, and the difficulties of assessing trace element status, as illustrated by states of potential subclinical deficiency of zinc and selenium in infants. Deficiency states of many trace elements have been documented in infants, ...
Innis S M - - 1997
The iron status and feeding practices of 434 infants in Vancouver were determined at 39 +/- 1 week of age. Iron-deficiency anaemia (haemoglobin < or = 101 g/L, or < or = 110 g/L with two or three abnormal results from tests of serum ferritin, zinc erythrocyte protoporphyrin and total ...
Hemalatha P - - 1997
Zinc status in 186 full term and preterm infants was determined at birth, and 3, 6, 9, and 12 months of age along with determination of zinc levels in breast or formula milk to find out if routine zinc supplements are needed during infancy. The leukocyte and plasma zinc levels ...
Geethanath R M - - 1997
OBJECTIVE: To determine the effect of timing of cord clamping on iron stores of term infants at 3 months of age. DESIGN: Prospective randomized clinical trial. SETTING: Tertiary hospital. SUBJECTS: 107 term neonates born to mothers with uncomplicated pregnancies and with hemoglobin more than 10 g/dl. METHODS: The 107 infants ...
Fomon S J - - 1997
Although feeding of formulas with iron concentration of 215 mumol/L (12 mg/L) is a reliable means of preventing iron deficiency, high intakes of iron may adversely affect absorption of copper and zinc. Because data are not available to establish whether fortification at a lower level would result in equivalent iron ...
Livingstone B - - 1997
Dietary prescriptions meant to reduce the risk of adult diseases could retard growth and development in infants and young children. Parents who pay attention to their infant's hunger or satiety signals will avoid under-feeding or over-feeding their infant. A useful guiding principle is that, as long as overall growth compares ...
Ziegler E E - - 1996
Iron deficiency is the most prevalent nutrition deficiency among infants and young children in industrialized as well as developing countries. It is a condition that is preventable through appropriate dietary measures. The infant born at term is endowed with a sizable amount of iron, which allows the infant to be ...
Al Hifzi I - - 1996
With a view to combating the long-term effects of iron deficiency anemia in infants, we carried out a screening program of infants at nine months of age in the Well Baby Clinic. We screened 4751 infants using complete venous blood count analysis, 2668 were anemic (Hb <11 gm/dL). Those with ...
Dorrepaal C A - - 1996
OBJECTIVE: To investigate if the availability of nonprotein-bound iron after birth asphyxia is related to the severity of the postasphyxial injury and neurodevelopmental outcome. METHODS: Nonprotein-bound iron (bleomycin assay) and thiobarbituric-acid-reactive species, an index of oxidative lipid damage, were measured in plasma of 50 newborn infants (gestational age > 34 ...
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