Search Results
Results 51 - 100 of 1500
1 2 3 4 5 6 7 8 9 10 >
Hehir Mark P - - 2013
We sought to compare maternal and neonatal outcomes in deliveries occurring overnight with those in daylight hours. Prospective observational study. Large national tertiary referral center. All singleton laboring nulliparous parturients delivering infants >500g over a 2 - year period, January 1(st) 2008 - December 31(st) 2009. Details of intrapartum characteristics ...
Rozance Paul J - - 2013
Neonatal hypoglycemia is one of the most common biochemical abnormalities encountered in the newborn. However, controversy remains surrounding its definition and management especially in asymptomatic patients. New information has been published that describes the incidence and timing of low glucose concentrations in the groups most at risk for asymptomatic neonatal ...
Yoo Ji Young Janice - - 2013
Recent studies have shown that hemorrhagic injury in the preterm cerebellum leads to long-term neurological sequelae, such as motor, affective, and cognitive dysfunction. How cerebellar hemorrhage (CBH) affects the development and function of the cerebellum is largely unknown. Our study focuses on developing a mouse model of CBH to determine ...
Saugstad Ola Didrik - - 2013
Background: The optimal oxygen saturation for extremely low birth weight infants in the postnatal period beyond the delivery room is not known. Objectives: To summarize and discuss the results of the randomized trials, constituting the NEOPROM (Neonatal Oxygenation Prospective Meta-analysis) collaborative study, examining the effect of low versus high functional ...
Schang Anne-Laure - - 2013
Preterm birth is very strongly associated with maternal/foetal inflammation and leads to permanent neurological deficits that correlate with white matter injury, including maturational arrest of oligodendrocytes and hypomyelination. Preterm birth and exposure to inflammation causes hypothyroxinemia. As such, supplementation with thyroxine (T4) seems a good candidate therapy for reducing white ...
Sadarangani Sapna P - - 2013
Brain abscesses in neonates are typically caused by Gram negative organisms. There are no previously described cases caused by Clostridium septicum. We present a case of a premature male infant who developed recurrent episodes of suspected necrotizing enterocolitis followed by brain abscesses, cerebritis and ventriculitis caused by Clostridium septicum.
Chau Vann - - 2013
Our objective was to determine the association of early brain maturation with neurodevelopmental outcome in premature neonates. Neonates born between 24 and 32 weeks' gestation (April 2006 to August 2010) were prospectively studied with MRI early in life and again at term-equivalent age. Using diffusion tensor imaging and magnetic resonance ...
de Vries Linda S - - 2013
Since the introduction of neonatal intensive care in the 1970s, there has been a pronounced decrease in overall mortality of premature infants as well as a decrease in the incidence of severe white matter injury, best known as cystic periventricular leukomalacia (c-PVL).(1) While cranial ultrasonography readily visualizes large lesions in ...
Sarginson Julia H - - 2013
Hair straighteners have become a popular and common household appliance. The incidence of burns from these devices is rising, and is of particular concern given that the main casualties are infants. We present the largest case series in the literature of paediatric burns from hair straightening devices. Retrospective data collection ...
Mallard Carina C Department of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, - - 2013
Cerebral palsy is one of the most devastating consequences of brain injury around the time of birth, and nearly a third of cases are now associated with premature birth. Compared with term babies, preterm babies have an increased incidence of complications that may increase the risk of disability, such as ...
Kumar S - - 2013
The main aim of this study was to determine the causes and epidemiological aspects of unnatural deaths in the elderly. Data were collected on 4405 male and female victims of unnatural deaths aged 50 years or more from the total number of 21,235 autopsies performed in King George's Medical University, ...
Soraisham Amuchou Singh AS Department of Paediatrics, University of Calgary, Alberta Children's Hospital Research Institute for Child and Maternal Health, Foothills Medical Centre, 1403, 29(th) Street NW Calgary, AB T2 N 2T9, Canada. Electronic address: - - 2013
To examine the neonatal mortality and morbidity of infants born at < 33 weeks gestational age (GA) who received extensive delivery room cardiopulmonary resuscitation (DR-CPR) immediately after birth. Design/Methods: In this retrospective cohort study, we performed secondary analyses of data from infants born at < 33 weeks GA and admitted ...
Lankarani Kamran B - - 2013
Road traffic crashes are the third highest cause of mortality in Iran. The aim of this study was to determine the impact of roadway environmental factors on traffic crash. This cross-sectional study was conducted in Iran between March 21, 2010 and December 30, 2010. The data on road traffic crashes ...
Stewart Camille L CL University of Colorado, Denver, CO, USA; Children's Hospital Colorado, Aurora, CO, USA. Electronic address: - - 2014
We observed a high incidence of traumatic brain injuries (TBI) in properly restrained infants involved in higher speed motor vehicle crashes (MVCs). We hypothesized that car safety seats are inadequately protecting infants from TBI. We retrospectively queried scene crash data from our State Department of Transportation (2007-2011) and State Department ...
Uche E O - - 2013
Neonatal head trauma resulting from causes other than birth trauma has rarely been the focus of many a research theme in the literature. To highlight the occurrence of non-birth trauma related neonatal head injury, and evaluate the causes and outcome of treatment. A 3 year retrospective review of neonatal patients ...
Carvalho Clarissa Gutierrez CG Hospital de Clínicas de Porto Alegre, Unidade de Terapia Intensiva Neonatal, Porto AlegreRS, Brasil, Unidade de Terapia Intensiva Neonatal, Hospital de Clínicas de Porto Alegre - HCPA - Porto Alegre (RS), - - 2013
In preterm infants, the need for intubation and mechanical ventilation is associated with ventilator-induced lung injuries and subsequent bronchopulmonary dysplasia. The aim of the present review was to improve the understanding of the mechanisms of injury that involve cytokine-mediated inflammation to contribute to the development of new preventive strategies. Relevant ...
Mahoney Ashley Darcy - - 2013
Even when it is just a few weeks before term gestation, early birth has consequences, resulting in higher morbidity and mortality. Respiratory issues related to moderate prematurity include delayed neonatal transition to air breathing, respiratory distress resulting from delayed fluid clearance (transient tachypnea of the newborn), surfactant deficiency (respiratory distress ...
Laptook Abbot R - - 2013
Common neurologic morbidities encountered in very preterm and extremely preterm infants (intracranial hemorrhage, white matter injury and periventricular leukomalacia, and apnea of prematurity) are much less common in moderately preterm and late preterm infants. The frequency of germinal matrix hemorrhage-intraventricular hemorrhage and white matter injury are reported to be low, ...
Haynes Robin L - - 2013
It has been widely suggested that brain damage in survivors of late preterm deliveries is similar to that in early preterm infants, only less severe. This report addresses this concept through reanalysis of published neuropathologic data obtained according to late preterm in comparison with early preterm ages. Findings suggest that ...
Pannek Kerstin - - 2013
Preterm birth is associated with an increased risk of adverse neurodevelopmental outcomes. Diffusion magnetic resonance imaging (dMRI) combined with tractography can be used to assess non-invasively white matter microstructure and brain development in preterm infants. Our aim was to conduct a systematic review of the current evidence obtained from tractography ...
Acres Meghan J - - 2013
Fatal non-accidental head injury (NAHI) in infancy is characterised by severe bilateral retinal haemorrhage (sbRH), thin film diffuse bilateral subdural haemorrhage (dbSDH) and severe fatal hypoxic ischaemic encephalopathy (sfHIE). The Geddes hypothesis is that sfHIE is the direct cause of sbRH and dbSDH. The conventional hypothesis (post-Geddes) is that trauma ...
Hilgendorff Anne - - 2013
Neonatal chronic lung disease (nCLD), also known as bronchopulmonary dysplasia (BPD), is the most common complication of premature birth, affecting up to 30% of very low birth weight infants. Improved medical care has allowed for the survival of the most premature infants, and significantly changed the pathology of BPD from ...
Finnie J W - - 2013
Expression of the immediate early gene, c-fos, was examined in a large animal model of non-accidental head injury ("shaken baby syndrome"). Lambs were used because they have a relatively large gyrencephalic brain and weak neck muscles resembling a human infant. Neonatal lambs were manually shaken in a manner similar to ...
Lee Kyung Eun - - 2013
This study investigated the socio-demographic characteristics and medical causes of death among meteorological disaster casualties and compared them with deaths from all causes. Based on the death data provided by the National Statistical Office from 2000 to 2011, the authors analyzed the gender, age, and region of 709 casualties whose ...
Hanif Hamed H Department of Neurosurgery, Sina Hospital, Tehran, - - 2013
Lipomyelomeningocele, a closed neural tube defect, usually occurs in lumbosacral area as a single lesion but can be associated with other spinal dysraphism. We report an infant with a very rare presentation of tandem lumbosacral lipomyelomeningoceles, thick filum terminale and split cord malformation.
Satyarthee Guru Dutta GD Department of Neurosurgery, All India Institute of Medical Sciences and Associated Jai Prakash Narayan Apex Trauma Centre, New Delhi, - - 2013
Subdural effusion (SDE) in an infant is a rare clinical scenario, which may be secondary to a variety of etiologies. Massive SDE is an extremely rare complication of head injury. It usually runs a self-limiting course. Though neurosurgical intervention is occasionally needed, different methods of surgical procedure for management includes ...
Olsen Emily A - - 2013
Every year, millions of children undergo anesthesia. Emerging evidence from experimental in-vitro and in-vivo models supports a role for neuropathologic injury and neurobehavioral deficits at older age after early exposure to various anesthetic regimens. Clinical studies have sought to identify a phenotype of developmental anesthesia neurotoxicity in humans, but the ...
Tsuji Takeshi - - 2013
Purpose: To clarify the differences between infants with periventricular hemorrhagic infarction (PVHI) and those with periventricular leukomalacia (PVL). Methods: We retrospectively evaluated the clinical features, ultrasonography, and electroencephalogram (EEG) findings in 22 preterm infants with PVHI and 49 with PVL. EEG and cranial ultrasonography were serially performed in all participants ...
Whyte Hilary E A - - 2013
Preterm births are increasing in number and while the rates of cerebral palsy have declined, there are increasing numbers of infants who survive with handicaps. In some studies, up to 50 % of children will have morbidity when followed up to school age. A review of current literature was conducted to ...
Sauber-Schatz Erin K - - 2013
Case reports and series have suggested an association between injury during pregnancy and several nervous system and nervous system-related adverse fetal/neonatal outcomes. This study's purpose is to further determine if there is an association between injury during pregnancy and nervous system birth defects in infancy. Through a case-control study, the ...
Zhong Shuang - - 2013
The 2010-2011 Queensland floods resulted in the most deaths from a single flood event in Australia since 1916. This article analyses the information on these deaths for comparison with those from previous floods in modern Australia in an attempt to identify factors that have contributed to those deaths. Haddon's Matrix, ...
Harteman Johanna C - - 2013
To investigate the relationship between placental pathology and pattern of brain injury in full-term infants with neonatal encephalopathy after a presumed hypoxic-ischemic insult. The study group comprised full-term infants with neonatal encephalopathy subsequent to presumed hypoxia-ischemia with available placenta for analysis who underwent cerebral magnetic resonance imaging (MRI) within the ...
Hillman Noah H NH Saint Louis Univ., Cardinal Glennon-Neonatology, 1100 South Grand, Saint Louis, MO 63104. - - 2013
Sustained lung inflations (SI) at birth may recruit functional residual capacity (FRC). Clinically, SI increase oxygenation and decrease need for intubation in preterm infants. We tested whether a SI to recruit FRC would decrease lung injury from subsequent ventilation of fetal, preterm lambs. The preterm fetus (128±1 day gestation) was ...
Ciambra G - - 2013
Cranial Ultrasound (cUS) may not be sensitive enough to detect subtle white matter (WM) injuries. Our study compared serial cUS with MRI at term equivalent age (TEA) to determine if it is possible to identify an ultrasound representation of subtle diffuse WM injuries such as punctate lesions (PWMLs) and diffuse ...
Tam Emily W Y - - 2013
The cerebellum undergoes dramatic growth and maturation over the neonatal period after preterm birth and is thus particularly sensitive to impaired development due to various clinical factors. Impairments in growth can occur independent of cerebellar parenchymal damage, such as from local hemorrhage, resulting from reduced expression of sonic hedgehog signaling ...
Raybaud Charles - - 2013
Neurodevelopmental outcome in prematures who suffer from a neonatal brain injury depends on the lesion itself, and on how the lesion interferes with the still developing functional anatomy. Most of the neuronal migration is completed by midgestation. The second part of the gestation corresponds to the development of the connectivity ...
Zhao Jing - - 2013
Intrauterine exposure of term and premature infants to infection/inflammation may increase the risk of perinatal brain injury, which may be more serious than that incurred by interpartum exposure to hypoxia-ischemia (HI). Many microorganisms, including certain viruses, protozoa, and bacteria, have been linked to this injury. In regard to the mechanisms ...
Nair V - - 2013
Glucose-6-phosphate dehydrogenase (G6PD) has an essential role in the defense against cellular oxidative injury. In neonates, the most common manifestation of G6PD deficiency is jaundice and hemolysis due to factors causing oxidative stress. Less known are the ocular associations described with G6PD deficiency, including cataracts. Oxidative injury is involved in ...
Ota Nathalie Tiemi - - 2013
To analyze the incidence of early-onset nasal injury in infants with very low birth weight and indication for noninvasive ventilation via nasal prongs. A prospective case series of infants with gestational age <37 weeks, weight <1.500 g and postnatal age <29 days. The patients were evaluated three times daily from ...
Bradford Ray - - 2013
Object The appearance and evolution of neuroimaging abnormalities following abusive head trauma (AHT) is important for establishing the time frame over which these injuries might have occurred. From a legal perspective this frames the timing of the abuse and therefore identifies and excludes potential perpetrators. A previous pilot study involving ...
Coleman Maya B MB Department of Psychiatry and Behavioral Sciences, Children's National Medical Center, Washington, DC, - - 2013
Neonatal Encephalopathy (NE) is a prominent cause of infant mortality and neurodevelopmental disability. Hypothermia is an effective neuroprotective therapy for newborns with encephalopathy. Post-hypothermia functional-anatomical correlation between neonatal neurobehavioral abnormalities and brain injury findings on MRI in encephalopathic newborns has not been previously described. To evaluate the relationship between neonatal ...
Becic Kristijan - - 2013
Aim. To investigate the mortality rate of foreign citizens in Croatia. Methods. Data were collected from the Departments for Forensic Pathology in Split and Rijeka, which are the autopsy centers of the counties with approximately 35% of total foreign visitors, as well as from the Croatian Central Bureau for Statistics ...
Marin Terri - - 2013
Necrotizing enterocolitis (NEC) is a disease primarily of prematurity characterized by partial or entire gut necrosis and is associated with significant mortality and morbidity. Recent studies report that approximately 25% to 35% of very low-birth-weight infants less than 1500 g receiving packed red blood cell transfusions develop temporally associated NEC, ...
Rios Danielle R - - 2013
The purpose of this study was to assess the utility of preoperative head ultrasound scan (HUS) in a cohort of newborns also under going preoperative MRI as part of a prospective research study of brain injury in infants having surgery for congenital heart disease(CHD). A total of 167 infants diagnosed ...
Duerden Emma G - - 2013
Infants born very preterm are high risk for acquired brain injury and disturbances in brain maturation. Although survival rates for preterm infants have increased in the last decades owing to improved neonatal intensive care, motor disabilities including cerebral palsy persist, and impairments in cognitive, language, social, and executive functions have ...
Benight Nancy M NM USDA/ARS Children's Nutrition Research Center, the Section of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Houston, TX 77030, - - 2013
Necrotizing enterocolitis (NEC) is complex disease thought to occur as a result of an immaturity of the gastrointestinal tract of preterm infants. Intestinal dysfunction induced by total parental nutrition (TPN) may increase the risk for NEC upon introduction of enteral feeding. We hypothesized that the intestinal trophic and anti-inflammatory actions ...
Di Fiore Juliann M - - 2013
With increased survival of preterm infants as young as 23 weeks gestation, maintaining adequate respiration and corresponding oxygenation represents a clinical challenge in this unique patient cohort. Respiratory instability characterized by apnea and periodic breathing occurs in premature infants because of immature development of the respiratory network. While short respiratory ...
Ritter Jonathan J Center for Neuroscience Research, Children's National Medical Center, Washington, District of Columbia 20010, - - 2013
The pathological mechanisms underlying neurological deficits observed in individuals born prematurely are not completely understood. A common form of injury in the preterm population is periventricular white matter injury (PWMI), a pathology associated with impaired brain development. To mitigate or eliminate PWMI, there is an urgent need to understand the ...
Rios Danielle R - - 2013
OBJECTIVE:The purpose of this study was to assess the utility of preoperative head ultrasound scan (HUS) in a cohort of newborns also undergoing preoperative MRI as part of a prospective research study of brain injury in infants having surgery for congenital heart disease (CHD).METHODS:A total of 167 infants diagnosed with ...
Wojtulewicz Julian P - - 2013
We hypothesise that the human infant, whether born prematurely or at term, may have special capacities when mounting a healing response to severe post-natal gastrointestinal injury consequent upon stem cells of endodermal origin, located in the infant gut, persisting beyond the intrauterine period. Should such endodermal stem cells persist beyond ...
1 2 3 4 5 6 7 8 9 10 >