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Chu Tracy T Brooklyn College, City University of New York, Department of Health and Nutrition Sciences, 2900 Bedford Avenue, Brooklyn, NY 11210, USA. Electronic address: - - 2014
Half of all births in New York City are to women born outside of the United States whose infant care practices may differ from official recommendations from the American Academy of Pediatrics. These infants have an overall lower infant mortality rate than those of their US-born counterparts. The aims of ...
Conroy N N Bo Government Hospital, Hospital Road, Bo District, Sierra - - 2014
Sierra Leone has the highest neonatal mortality rate in the world, with one in 20 infants not surviving the neonatal period(Approx50 deaths per 1,000 live births)(1). Just over a third (35%) of these newborns die within 24 hours of delivery(2). There is evidence that neonatal resuscitation programmes in low-resource settings ...
Kazanskaya G M GM E. N. Meshalkin Novosibirsk State Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation, Novosibirsk, Russia, - - 2014
Surgical correction of complicated congenital heart disease in infants is terminated by postischemic reperfusion of myocardium accompanied with closure of more than 20% microvessels in the coronary bed by edematous endothelial cells, their bleb-like fragments, and aggregates of the blood formed elements. Degradation of the transmission capacity of the coronary ...
Petska Hillary W HW Children's Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, WI, - - 2014
Injuries, other than abrasions, are rare in precruising infants. In this population, a history or observation of a sentinel skin injury, intraoral injury, or musculoskeletal injury without a plausible explanation, is concerning for physical abuse. A precruising infant with a sentinel injury should be medically evaluated for occult injury and ...
Pontarelli Elizabeth M EM From the *Children's Hospital Los Angeles, Los Angeles, CA and †Randall Children's Hospital, Portland, - - 2014
Nonaccidental trauma (NAT) is most common and most lethal in infants. Falls are the most frequently given explanation for NAT, and head injuries can result from both mechanisms. We hypothesized that infant head injuries from NAT have a distinct injury profile compared to falls. The trauma registry and patient records ...
Bonfim Suely de Fátima Santos Freire SD Unidade Neonatal, Hospital das Clínicas, Universidade Federal de Pernambuco, Recife, PE, - - 2014
to assess the incidence and risk factors associated with nasal septum injury in premature infants using reused and new nasal prongs. the study was a cohort from an open therapeutic intervention. The sample included 70 infants with a gestational age inferior to 37 weeks, who used nasal prongs and were ...
Brossard-Racine Marie M Advanced Pediatric Brain Imaging Research Laboratory, Children's National Health System, Washington, DC, USA, - - 2014
Cerebellar injury is increasingly recognized as an important complication of very preterm birth. However, the neurodevelopmental consequences of early life cerebellar injury in prematurely born infants have not been well elucidated. We performed a literature search of studies published between 1997 and 2014 describing neurodevelopmental outcomes of preterm infants following ...
McHoney Merrill M Department of Paediatric Surgery, Royal Hospital for Sick Children, Sciennes Road, Edinburgh, EH9 1LF, UK, - - 2014
A neonate with gastroschisis had silo placement and near-infrared spectroscopy (NIRS) monitoring of intestinal haemoglobin oxygen saturation (RSO2). An ischemic loop of bowel demonstrated decreased RSO2, with reversal of clinical ischemia and RSO2 postoperatively. This demonstrates possible advantage of monitoring intestinal RSO2 in neonates at risk of ischemia, and response ...
Benkoe Thomas M TM Department of Pediatric Surgery, Medical University of Vienna, Waehringerguertel 18-20, 1090-Vienna, Austria. Electronic address: - - 2014
Intestinal ischemia plays a major role in the pathogenesis of necrotizing enterocolitis (NEC). The diagnosis of intestinal ischemia would be highly desirable, as is it impossible to achieve with current diagnostic regimes. Preliminary data from an animal NEC model indicate a possible correlation between plasma activity of the lysosomal enzyme ...
Monroe Kathy K From the Pediatric Emergency Medicine (K.M., M.N., W.D.K.), and SafeKids of Alabama (M.C.), Southeast Child Safety Institute (W.D.K.), Children's of Alabama (E.I.), University of Alabama Hospital Systems, Birmingham; and Center for Advanced Public Safety (J.N.), The University of Alabama, Tuscaloosa, - - 2014
Motor vehicle crashes (MVCs) are a leading cause of morbidity and mortality in teens. Alabama has been in the Top 5 states for MVC fatality rate among teens in the United States for several years. Twelve years of teen MVC deaths and injuries were evaluated. Our hypothesis is that the ...
Alaro Dan D Department of Paediatrics and Child Health, University of - - 2014
The kidney is the most damaged organ in asphyxiated full-term infants. The severity of its damage is correlated with the severity of neurological damage. We determined the prevalence of perinatal asphyxia-associated acute kidney injury (AKI). We conducted a prospective cohort study including 60 full-term neonates admitted at the Kenyatta National ...
Donn Steven M SM Department of Pediatrics, Division of Neonatal-Perinatal Medicine, C.S. Mott Children's Hospital, University of Michigan Health System, Ann Arbor, MI, USA. Electronic address: - - 2014
Medical malpractice litigation in the USA and much of the developed world has reached near-epidemic proportions. Brain-damaged infants are among the most costly medical malpractice lawsuits, with the average indemnity for these cases being $524,047. Hypoxic-ischemic encephalopathy (HIE) is the most common birth injury claim, generally alleging that intrapartum asphyxia ...
Polka Linda L School of Communication Sciences and Disorders, McGill University Centre for Research on Brain, Language and Music, McGill University - - 2014
Little is known about infants' abilities to perceive and categorize their own speech sounds or vocalizations produced by other infants. In the present study, prebabbling infants were habituated to /i/ ("ee") or /a/ ("ah") vowels synthesized to simulate men, women, and children, and then were presented with new instances of ...
Kocaoglu Celebi - - 2014
In developed countries, vitamin B12 (cobalamin) deficiency usually occurs in children, exclusively breastfed ones whose mothers are vegetarian, causing low body stores of vitamin B12. The haematologic manifestation of vitamin B12 deficiency is pernicious anaemia. It is a megaloblastic anaemia with high mean corpuscular volume and typical morphological features, such ...
Cottron Nicolas N From the Department of Anesthesiology and Intensive Care, University Hospital of Toulouse, Toulouse, IFR, - - 2014
Preoperative flushing of an anesthesia workstation is an alternative for preparation of the anesthesia workstation before use in malignant hyperthermia-susceptible patients (MHS). We studied in vitro, using a test lung, the washout profile of sevoflurane in 7 recent workstations during adult and, for the first time, pediatric ventilation patterns. Anesthesia ...
Hunter Linda A - - 2014
Since the publication of the Term Breech Trial in 2000, planned cesarean has become the preferred mode of birth for women whose fetus is in a breech presentation. Over the past 20 years, however, subsequent evidence has not shown conclusively that cesarean birth is safer than vaginal birth for a ...
Kumar Praveen P Division of Newborn Medicine, Department of Pediatrics, Batson Children's Hospital, The University of Mississippi Medical Center, Jackson, MS, 39216-4505, USA, - - 2014
The Neonatal Resuscitation Program (NRP) consists of an algorithm and curriculum to train healthcare professionals to facilitate newborn infants' transition to extrauterine life and to provide a standardized approach to the care of infants who require more invasive support and resuscitation. This review discusses the most recent update of the ...
Mayor Julien J FPSE, University of Geneva, - - 2014
The TRACE model of speech perception (McClelland & Elman, 1986) is used to simulate results from the infant word recognition literature, to provide a unified, theoretical framework for interpreting these findings. In a first set of simulations, we demonstrate how TRACE can reconcile apparently conflicting findings suggesting, on the one ...
Amirav Israel I Pediatric Department, Faculty of Medicine, University of Alberta, Edmonton, Alberta, Canada; University of Alberta, Edmonton, Alberta, - - 2014
The oral route has been considered superior to the nasal route for aerosol delivery to the lower respiratory tract (LRT) in adults and children. However, there are no data comparing aerosol delivery via the oral and nasal routes in infants. The aim of this study was to compare nasal and ...
Kulkarni Ambadas A Oral and Maxillofacial Surgery, Government Dental College, Calicut, - - 2014
Injuries to the parotid duct and parenchyma resulting in swelling in the cheek region commonly present in maxillofacial practice. Sialocele is a discrete collection of saliva in a subcutaneous cavity that can be iatrogenic, idiopathic or the result of post-traumatic injuries to the duct or parenchyma, presenting as a salivary ...
Longest P Worth - - 2013
Abstract Purpose: The objective of this study was to determine optimal aerosol delivery conditions for a full-term (3.6 kg) infant receiving invasive mechanical ventilation by evaluating the effects of aerosol particle size, a new wye connector, and timing of aerosol delivery. Methods: In vitro experiments used a vibrating mesh nebulizer and ...
Wong Carrie F P CF Department of Anaesthesiology, Queen Mary Hospital, Hong Kong, - - 2014
Limited information is available on the management of the 'cannot intubate, cannot ventilate' (CICV) situation in infants. We compared the time to achieve adequate oxygenation following rescue ventilation using the Enk oxygen flow modulator (OFM) with a jet ventilator in a simulated CICV situation using the rabbit as an infant ...
Voorthuis Alexandra - - 2013
Children vary hugely in how demanding of their caregivers they are. This creates differences in demands on parents during observation, making the comparison of sensitivity between parents difficult. It would therefore be of interest to create standard situations in which all caregivers are faced with the same level of demand. ...
Chang Brent A - - 2013
We report a 1month old infant with a spontaneously knotted nasogastric tube. Attempted removal of the nasogastric tube was unsuccessful, prompting further investigation. Plain radiographs revealed a large, multi-looped knot impacted in the nasopharynx and oropharynx. The tube was subsequently removed through the mouth under general anesthesia without complication, revealing ...
Cohen-Wolkowiez Michael M From the *Department of Pediatrics, Duke University; †Duke Clinical Research Institute, Durham, NC; ‡Wichita Medical Research and Education Foundation, Wichita, KS; §Division of Infectious Diseases, CHOC-Children's Hospital of Orange County, Orange, CA; ¶Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Vanderbilt University Medical Center, Nashville, TN; ‖EMMES Corporation, Rockville, MD; **Department of Pediatrics, University of Missouri-Kansas City School of Medicine and the Division of Pediatric Pharmacology and Therapeutic Innovation, The Children's Mercy Hospital, Kansas City, MO; ††Department of Pediatric Pharmacology, University of California, San Diego, CA; and ‡‡Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, - - 2013
Limited pharmacokinetic (PK) data of metronidazole in premature infants have led to various dosing recommendations. Surrogate efficacy targets for metronidazole are ill-defined and therefore aimed to exceed minimum inhibitory concentration of organisms responsible for intra-abdominal infections. We evaluated the PK of metronidazole using plasma and dried blood spot samples from ...
Farney Kimberly D - - 2013
Nasal Continuous Positive Airway Pressure (NCPAP) is widely used in neonatal intensive care units. Aerosolized medications such as inhaled steroids and beta-agonists are commonly administered in-line through NCPAP, especially to infants with bronchopulmonary dysplasia (BPD). We hypothesized that aerosol delivery to the lungs via variable flow NCPAP in an in ...
Rutherford Helena J V HJ Yale Child Study Center, Yale School of Medicine, University of Leuven, Northern Illinois University, Belgium. Electronic address: - - 2013
Parental reflective functioning represents the capacity of a parent to think about their own and their child's mental states and how these mental states may influence behavior. Here we examined whether this capacity as measured by the Parental Reflective Functioning Questionnaire relates to tolerance of infant distress by asking mothers ...
Dellimore Kiran - - 2013
Optimizing chest compression (CC) performance during neonatal cardiopulmonary resuscitation (CPR) is critical to improving survival outcomes since current clinical protocols often achieve only a fraction of the native cardiovascular perfusion. This study presents the development of a diagnostic tool to unobtrusively measure the CC depth and force during neonatal CPR ...
Lew Seok S Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 13th Street, Suite 2301, Charlestown 02129, USA. - - 2013
In infants, the fontanels and sutures as well as conductivity of the skull influence the volume currents accompanying primary currents generated by active neurons and thus the associated electroencephalography (EEG) and magnetoencephalography (MEG) signals. We used a finite element method (FEM) to construct a realistic model of the head of ...
Luque Veronica - - 2013
: The estimation of dietary intake remains a challenge in human nutritional studies. In infants, the use of food diaries (FDs) is a suitable method already validated; however, this method is not exempt from error. In formula-fed infants, dilution of powdered formulas may produce errors. Our aim was to develop ...
Ball Gareth G Centre for the Developing Brain, Division of Imaging Sciences & Biomedical Engineering, King's College London, London, United Kingdom. - - 2013
Early neuroimaging may provide a surrogate marker for brain development and outcome after preterm birth. Tract-Based Spatial Statistics (TBSS) is an advanced Diffusion Tensor Image (DTI) analysis technique that is sensitive to the effects of prematurity and may provide a quantitative marker for neuroprotection following perinatal brain injury or preterm ...
Martin Philip Stephen - - 2012
BACKGROUND: Morbidity and mortality remain high following infant cardiac arrest. Optimal cardiopulmonary resuscitation (CPR) is therefore imperative. OBJECTIVE: Comparison of two-thumb (TT) and two-finger (TF) infant chest compression technique compliance with international recommendations. DESIGN: Randomised cross-over experimental study. METHODS: Twenty-two certified Advanced Paediatric Life Support (APLS) instructors performed 2 min ...
Valcke Mathieu - - 2012
The objective of this study was to evaluate the impact of interindividual differences in hepatic first-pass effect (FPE) on the magnitude of the human kinetic adjustment factor (HKAF) for ingested toxicants. This factor aims at replacing a default value of 3.2 used in non-cancer risk assessment. Coupled with Monte Carlo ...
Chitkara Ritu - - 2012
OBJECTIVE: To compare a novel neonatal resuscitation cart (NRC) to a generic code cart (GCC). STUDY DESIGN: A prospective, randomised, controlled, crossover trial was performed to compare the utility of the NRC with the GCC during simulated deliveries of extremely low birthweight infants and infants with gastroschisis. Fifteen subjects participated. ...
Donoghue Aaron J - - 2012
STUDY OBJECTIVE: We determine whether videolaryngoscopy results in a higher prevalence of first-attempt intubation success and improved glottic visualization than direct laryngoscopy when performed by pediatric emergency medicine providers in simulated patients. METHODS: This was a cross-sectional study at a single institution. Fellows and faculty in pediatric emergency medicine were ...
Ramani Manimaran M Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, - - 2013
Extremely premature infants are often exposed to supra-physiologic concentrations of oxygen, and frequently have hypoxemic episodes. These preterm infants are at high risk (~40%) for neurodevelopmental impairment (NDI) even in the absence of obvious intracranial pathology such as intraventricular hemorrhage or periventricular leukomalacia. The etiology for NDI has not been ...
Mammarella Nicola - - 2012
Two studies examined the effects of different socio-affective factors on risk driving behaviour. In Experiment 1, 87 adult drivers we asked to play a computer-based driving game after being exposed to a series of images that depicted infants, police or neutral information (control condition). In Experiment 2 we tested a ...
Cohen Gary G Department of Neonatal Medicine, Royal Prince Alfred Hospital, Sydney, Australia. - - 2012
A resumption of, and escalation in, breathing efforts (hyperpnoea) reflexively accelerates heart rate (HR) and may facilitate cardiac and circulatory recovery from apnoea. We analysed whether this mechanism can produce a sustained rise in HR (tachycardia) when a sleeping infant is confronted by mild, rapidly worsening asphyxia, simulating apnoea. Twenty-seven ...
Goracy Iwona - - 2012
INTRODUCTION: Left ventricular mass (LVM) is a strong predictor of various heart diseases. We examine the association between the G(-6)A AGT, I/D ACE, A1166C AGTR1, T(-344)C CYP 11β2, A538G MR and A10631G REN polymorphisms and LVM and blood pressure in newborn infants. MATERIAL AND METHODS: The study included 211 healthy ...
Yıldırım Zeynep Hoşbay - - 2012
The main object of the present study is to assess neuromotor development of high-risk infants by using three tests, and to determine inter-test concordance and the feasibility of these tests. One-hundred and nine patients aged between 0 and 6 months and identified as "high-risk infant" according to the Kliegman's criteria ...
Wang Ya-Chen - - 2012
To evaluate the effects on neonatal outcomes between very-low-birth-weight (VLBW) preterm newborns with and without maternal use of antenatal corticosteroids (ACS). We retrospectively reviewed medical records of VLBW premature infants who were admitted to Kaohsiung Medical University Hospital between 1999 and 2008. A total of 256 infants were enrolled in ...
Imasawa Toshiyuki - - 2012
BACKGROUND: An ecological study is a useful epidemiologic tool for public health surveillance and establishment of a new hypothesis. Here, we used an ecological study to analyze the association between birth weight and end-stage renal disease (ESRD). METHODS: We performed ecological regression analysis by using data obtained from the national ...
Clark Steven L - - 2012
The death of a mother during or after childbirth is one of the most tragic events in medicine. We have identified 10 specific recurrent errors that account for a disproportionate share of maternal deaths, primarily related to pulmonary embolism, severe preeclampsia, cardiac disease, and postpartum hemorrhage. Attention to these principles ...
Schuurhof Annemieke - - 2012
Severity of respiratory syncytial virus (RSV) infection ranges widely. To what extent the local immune response is involved in RSV disease pathogenesis and which markers of this response are critical in determining disease severity is still a matter of debate. The local immune response was studied in nasopharyngeal aspirates (NPAs) ...
Jetton Jennifer G - - 2012
PURPOSE OF REVIEW: Acute kidney injury (AKI) is associated with increased risk of morbidity and mortality in critically ill children and adults. Neonates remain an understudied group, although previous evidence suggests that this association holds true for them as well. RECENT FINDINGS: Attention to the issue of neonatal AKI is ...
Bergstrom Kendra Gail - - 2012
Atopic dermatitis is increasing in prevalence throughout the developed world, in parallel with asthma and hay fever. The reasons for the increase remain unclear. As a practical question, it is valuable to understand which interventions might decrease risk for childhood atopic disease. Prospective studies among infants and children are challenging ...
Nagarakanti S - - 2012
Disorders relating to short gestation and low birth weight are among the leading causes of death and disability in infants. About 25% of pre-term low birth weight (PLBW) cases occur without even a suspected risk factor. Of all PLBW cases, 18.2% may be attributable to periodontitis ( Offenbacher et al. ...
Alberts Jeffrey R - - 2012
Understanding the developmental origins of congenital capabilities such as sucking is fundamental knowledge that can contribute to improving the clinical management of early feeding and facilitate the onset of oral ingestion. We describe analyses in rats showing that sensory stimulation in utero and during birth establishes the newborn's sucking responses ...
Volonaki Eleni - - 2011
OBJECTIVES:: Lower threshold and widening indications for pediatric gastrointestinal endoscopy has resulted in significant increase in the numbers of endoscopic procedures performed in infants. Despite this, knowledge of gastrointestinal mucosal findings in this age group is limited and data on the clinical usefulness of endoscopy are lacking. METHODS:: All children ...
Machaira Maria - - 2011
Kawasaki disease (KD) is a systemic vasculitis of unknown etiology presenting typically in infants and young children. We report a rare case of incomplete KD in a 15 months' old male infant presenting with symptoms mimicking retropharyngeal abscess and intermittent fever.
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