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Heath D - - 1990
A histological study was made of the carotid bodies obtained at necropsy in 40 fetuses, neonates, infants and young children, ranging in age from 23 weeks of gestation to 11 years of age. Prominence of the dark variant of chief cells was found in diseases such as bronchiolitis which are ...
Chapell M S - - 1990
Evidence is presented to show that standard mattresses compress infants enough to increase the work required to maintain normal levels of ventilation and cellular respiration. The possible relation of long-term standard mattress compression to Sudden Infant Death Syndrome is proposed. Evidence is presented to show that waterbeds do not compress ...
Shell W E - - 1990
As worded, the question "Should silent ischemia be treated?" needs to be examined carefully, assuming that silent ischemia is even the correct topic of the question. The way the question is phrased influences the answer. The more the question's permutations are examined, the clearer it becomes that the problem is ...
Meadow R - - 1990
We reviewed the cases of 27 young children from 27 different families who were suffocated by their mothers. The certainty, or near certainty, of suffocation was based on reliable observation or recording of the suffocation, maternal confession, or successful prosecution in a criminal court. Eighteen of the children are alive, ...
Kyle D - - 1990
Among the 45,204 live births in Birmingham in the three calendar years 1981-3, there were 218 postneonatal deaths, giving a postneonatal mortality rate of 4.82 per 1000 live births. Postneonatal mortality rates were 4.22 for whites, 5.91 for Asians (relative risk 1.26, 95% confidence interval (CI) 1.04 to 1.53) and ...
Fleming P J - - 1990
OBJECTIVE: To determine the relation between sleeping position and quantity of bedding and the risk of sudden unexpected infant death. DESIGN: A study of all infants dying suddenly and unexpectedly and of two controls matched for age and date with each index case. The parents of control infants were interviewed ...
Jagoda A - - 1990
Infant botulism occurs in infants between 1 week and 11 months of age and results from the in vivo production of neurotoxin by Clostridium botulinum. The clinical spectrum ranges from asymptomatic carriers, through various degrees of paralysis, to sudden death. The classic clinical presentation is an afebrile child with constipation ...
Jay V - - 1990
Dendritic arborization patterns of visual cortical neurons in four cases of trisomy 18 syndrome were compared with those in 8 neurologically asymptomatic age-matched controls. The trisomy cases included a 20-week-old fetus, a term infant, a 3-month-old infant, and 6-month-old infant. Quantitative Golgi analysis showed a decrease in the mean total ...
Guntheroth W G - - 1990
To determine the risk of recurrence of sudden infant death syndrome in families, we studied 251,124 live births by linked birth and death certificates from Oregon for a 10-year period. We found five recurrences among 385 subsequent siblings, for a rate of 13/1000 live births and a relative risk of ...
Grether J K - - 1990
We analyzed California linked birth and infant death records for 1978 to 1985 to determine the ethnic-specific incidence of sudden infant death syndrome in five Asian-American subgroups, and to assess the association of sudden infant death syndrome with cultural assimilation. The overall incidence of sudden infant death syndrome for these ...
Parnes S - - 1990
A diagnosis of Smith-Lemli-Opitz syndrome was made shortly after birth in a small-for-dates infant, on the basis of a characteristic face, penoscrotal hypospadias, bilateral postaxial hexadactyly, and bilateral syndactyly of toes 2-3. The clinical course was marked by failure to thrive, severe delay, refractory myoclonic jerks beginning at age 2 ...
Takashima S - - 1990
Morphometric Golgi methods were used to study dendritic development of neurons in the cervical ventral and dorsal horns and the hypoglossal nucleus of 8 victims of sudden infant death syndrome and 20 age-matched control infants. The dendrites and spines of these neurons proliferated rapidly until 28 weeks gestation, then increased ...
Hagadorn J I - - 1990
We report on an infant with the neonatal progeroid syndrome whose clinical course and autopsy findings indicate that this may be a heterogeneous phenotype. The infant had intrauterine growth retardation, absence of subcutaneous fat, and a wizened, aged face, all apparently characteristic of the condition, but also had congenital heart ...
Carpenter R G - - 1990
Sudden infant death syndrome (SIDS) death rates show substantial seasonal variation. Analysis of this variation shows that it is due to postnatal factors. Possible variables are temperature, infection, pollution, and the infants' interaction with the social environment. In England and Wales the temporal pattern of pollution levels and the geographical ...
Cotter P D - - 1990
Described is an infant with partial trisomy 17q and monosomy 9p [46,XX,-9,+der(9)t(9;17)(p21;q23)] due to adjacent-1 segregation of a maternal balanced reciprocal translocation. Characteristic clinical features of both partial 17q trisomy and monosomy 9p are present, but the former syndrome is less recognisable in this infant than in previously reported cases ...
Johnson C J - - 1990
The contamination of groundwater and rural drinking water supplies by nitrates from livestock and human excrement, other organic waste, or chemical fertilizers is a potential hazard throughout the world. Infant illness and death from nitrate-induced methemoglobinemia is probably often misdiagnosed, perhaps as sudden infant death syndrome, and certainly contributes to ...
Tyler J W - - 1989
The Cot-death Syndrome is an out-moded model which is bizarre and unique in medical history for it enables a certificate of cause of death to be issued only if no medical cause can be found. It rewards incompetence. Apart from being a placebo for bereaved parents and a lucrative source ...
Timens W - - 1989
The immune response to polysaccharide Ag as present in the capsule of certain virulent bacteria has been demonstrated to be related to a functionally intact spleen. This immune response is almost completely defective in infancy. Because of this the development of cellular compartments in the human spleen was studied immunohistologically ...
MacDonald A B - - 1989
Great diversity of clinical expression of signs and symptoms of gestational Lyme borreliosis parallels the diversity of prenatal syphilis. It is documented that transplacental transmission of the spirochete from mother to fetus is possible. Further research is necessary to investigate possible teratogenic effects that might occur if the spirochete reaches ...
Goren A - - 1989
A 5.5-month-old male infant with hypokalaemia and gall bladder dilatation is reported. The child was shown to have Bartter syndrome. After oral treatment with potassium and indomethacin, serum potassium levels became low normal and the gall bladder enlargement resolved. This entity should be included in the clinical spectrum of neuromuscular ...
Campbell M J - - 1989
All cases of sudden infant death syndrome that occurred in New South Wales in the period January 1, 1981 to November 30, 1985 were studied in relation to the environmental temperature which was recorded in Sydney. A significant (P = 0.009) negative correlation was found between a change in temperature ...
Farhud D D - - 1989
A male infant is presented with wide fontanels, micrognathia, mid-face hypoplasia, hypertelorism, broad nasal root, down-slanting palpebral fissures, small thorax, funnel chest, short wide toes, camptodactyly and cutaneous syndactyly of fingers and toes, dysplastic bones with thin wavy ribs and bowed femore, cryptorchidism, and hypospadias grade I. The mother of ...
Adams R H - - 1989
A newborn with Down syndrome was noted on the 1st day of life to have an elevated white blood cell count of 79,900/mm3 with 62% lymphoblasts and a platelet count of 61,000/mm3, consistent with either transient myeloproliferative disorder of Down syndrome (TMD) or acute leukemia. Karyotype analysis of a bone ...
Takashima S - - 1989
Clinical and neuropathologic studies were performed in 5 infants who had brainstem or cerebellar infarction and respiratory control abnormalities during early infancy. The anatomic distribution of brainstem infarction was closely related to the failure of neural respiratory control as was unilateral cerebral hemorrhagic infarction to sudden death. Brainstem and cerebellar ...
Pasi A - - 1989
The regional levels' profile of human beta-endorphin (beta h-EP) was studied in the brainstem and the cerebellum of 16 infant victims of "Sudden Infant Death Syndrome" and other death causes. An immunoaffinity chromatography procedure based on a monoclonal antibody directed specifically against the N-terminus of beta-EP was used to extract ...
Stephan M J - - 1989
We describe two female infants with Hurler syndrome (mucopolysaccharidosis I) whose deaths are attributed to cardiac failure with associated, autopsy-confirmed endocardial fibroelastosis. One infant had confirmed alpha-L-iduronidase deficiency in cultured dermal fibroblasts, and the other infant had histologic evidence of tissue mucopolysaccharide accumulation at autopsy and a sibling with confirmed ...
Stone D H - - 1989
Examination of data from the Glasgow Registry of Congenital Anomalies indicated that 184 infants with Down's syndrome were born (live or still) to mothers residing in the Greater Glasgow Health Board area between 1974 and 1986 inclusive. This represents a period prevalence of 1.1 per 1000 total births. Despite a ...
Sexson W R - - 1989
Withdrawal emergent syndrome (WES) is a subtype of tardive dyskinesia that has been reported in children who were taken off antipsychotic therapy. We present the first case of WES in an infant born to a mother taking haloperidol during her pregnancy. The infant developed repeated tongue thrust, abnormal hand posturing, ...
Källén B - - 1989
The date of stopping oral contraceptives (OC) in relation to the last menstrual period was studied in 458 women with Down syndrome infants born in 1983-1986 and compared with the expected distribution estimated from the total population of births for these years, after stratification for year of birth, maternal age, ...
Mallory S B - - 1989
An infant with congenital ichthyosis and deafness developed Hirschsprung's disease. No evidence of keratitis was present. No previous cases of ichthyosis have been associated with aganglionic megacolon. Although no corneal changes were observed, we believe that the clinical features of ichthyosis and deafness suggest the diagnosis of KID (keratitis, ichthyosis, ...
Forsyth K D - - 1989
The incidence of the sudden infant death syndrome parallels that of respiratory tract infections in the paediatric community. On the basis that the aetiology of the sudden infant death syndrome may lie in an unusual response to a trivial intercurrent respiratory infection a necropsy study was carried out investigating pulmonary ...
Lorenzana A N - - 1989
We report a 3 1/2-week-old male infant with Down's syndrome who presented with abdominal distention, ascites, and eosinophilia and was subsequently diagnosed as having an abdominal non-Hodgkin's lymphoma of T-cell type. Because of the unusual association of these two conditions, especially at this early age, the literature was reviewed regarding ...
Oehmichen M - - 1989
The study was based on the hypothesis that cerebellar hypoxia may play a role in sudden infant death syndrome resulting in morphological changes of the cerebellar cortex, especially with respect to Purkinje cell density. In the morphological evaluation of the Purkinje cell layer, special consideration was additionally given to secondary ...
Shimozawa N - - 1988
Rectal mucosa biopsy specimens from five controls and three infants with Zellweger syndrome were investigated morphologically and biochemically to elucidate peroxisomal structure and functions in the human rectal mucosa and to develop a simple method for an early postnatal diagnosis of peroxisomal deficiency disorders. After the alkaline 3,3'-diaminobenzidine reaction, peroxisomes ...
Martínez-Frías M L - - 1988
We studied the birth prevalence of autosomal dominant mutations in Spain and estimated how a decrease in maternal age distribution may lead to reduction in dominant mutations. The data were collected by the Estudio Colaborativo Español de Malformaciones Congénitas from April, 1976, to December, 1985. Among 553,270 liveborn infants monitored ...
Gozal D - - 1988
A central hypoventilatory state developed in a 6-month-old boy with environmentally induced hyperthermia. The condition subsided within 24 hours of mechanical ventilation. Hypoxic and hypercapneic challenges performed 2 weeks later showed complete resolution of the respiratory chemoreceptor dysfunction. The damage to the CNS caused by accidental hyperthermia in general, and ...
Ramabadran K - - 1988
Milk from breast or baby formula is the exclusive source of nutrition for newborn infants. Short chain opioid peptides such as beta-casomorphins have been isolated from breast milk as well as baby formula. These biologically active peptides are absorbed from the gastrointestinal tract. In infants predisposed to respiratory apnea because ...
Homans A C - - 1988
The syndrome of thrombocytopenia with absent radii (TAR) is a hereditary condition whose pathogenesis is poorly understood. In this investigation we evaluated a female infant with TAR and her parents using in vitro haematopoietic colony forming assays and an antiserum against platelet membrane glycoproteins (PGP) to label smears of her ...
Meny R G - - 1988
During a two-year period, ten infants died suddenly and unexpectedly with a home cardiorespiratory monitor available. We investigated the compliance with appropriate monitoring technique as well as the medical and demographic factors associated with these deaths (90% were due to sudden infant death syndrome). At least six and probably eight ...
Dunst C J - - 1988
The relative amount of time necessary to move from stage-to-stage during the sensorimotor period was examined among a group of 30 Down's syndrome and 12 non-retarded infants. Stage transitioning was examined for the four transitional points between Stages II and VI for the seven branches of sensorimotor development on the ...
Devine W A - - 1988
An infant with trisomy 21 and tracheostenosis is described. Postmortem findings included symmetrical bronchi, normal atrial arrangement ("situs") and anomalous thoracic vessels. The lack of concordance between the bronchial morphology and atrial arrangement supports the premise that atrial morphology is a more accurate predictor of the presence or absence of ...
Huber K H - - 1988
A tilt-table test was performed on 12 untrained subjects to evaluate the humoral adaptation to postural change. The observed peripheral reaction with a reversible short-term rise of norepinephrine (NE) and plasma renin activity (PRA) allowed us to divide the syndrome of the orthostatic dysregulation into a hyponoradrenergic and hypernoradrenergic type. ...
Nelson E A - - 1988
There is considerable regional variation in postneonatal mortality rates within New Zealand. The majority of postneonatal deaths are recorded as sudden infant death syndrome, and the regional rates of these deaths show a significant negative correlation with the mean daily temperature and mean 0900 hr vapour pressure (p less than ...
al-Qudah A A - - 1988
A term female infant had the clinical manifestations and accompanying electrophysiologic studies to fulfill the criteria of Guillain-Barré syndrome. At birth, she presented with generalized hypotonia, paucity of lower limb movements, and diminished muscle stretch reflexes. At 3 weeks of age, motor nerve conduction studies demonstrated evidence of demyelination and ...
Borman B - - 1988
Although the sudden infant death syndrome is a major component of New Zealand's high postneonatal mortality rate, little is known about its national epidemiological patterns. In this paper, based on all cases born during 1981-83, the rate of sudden infant death syndrome was 4.2/1000 livebirths. The rate declined with maternal ...
Shiono H - - 1988
Two autopsied cases are presented, one involving a 5-month-old infant, and a 6-month-old infant both of whom died suddenly and unexpectedly. The incidence of sudden infant death syndrome in Japan is 1.2 per 1,000 babies live births. Among all cases autopsied in the departments of legal or forensic medicine in ...
Parkin A J - - 1988
This study explores metamemory in both amnesic and normal adult subjects. In this context metamemory is defined as an individual's knowledge about the functioning of memory in general rather than an individual's knowledge of their own memory. The amnesic patients were divided into those suffering from Korsakoff's Syndrome and a ...
Nelson E A - - 1988
Haemorrhagic shock encephalopathy syndrome is a recently described condition which appears to be an important cause of infant mortality and morbidity. Six infants, with some features of this condition, admitted to Dunedin Hospital during the last three years, are presented and their diagnoses reviewed. Diagnostic overlap may occur between haemorrhagic ...
Baccino E - - 1988
This study focused on the frequency of pathological acid gastroesophageal reflux (AGER) on 50 children considered to be at risk for sudden infant death syndrome: that is to say, 30 near misses and 20 subsequent siblings. Four parameters were studied in a 24-h pH metry: (1) The percentage of time ...
Forsyth K D - - 1988
The phenotype of cells obtained from pulmonary lavage in infants who have died from sudden infant death syndrome were examined and compared with cells from control subjects. The only striking difference between the groups was a lack of reactivity of lavage cells with antibody of the CD14A cluster in the ...
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