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Results 251 - 300 of 619
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Maurizi C P - - 1997
Hypoplastic pineal glands and decreased melatonin levels are found in sudden infant death syndrome. Excess oxygen radical production and inadequate radical quenching is suggested to cause oxidative stress in the brain of sudden infant death syndrome victims. Loss of intraventricular cerebrospinal fluid melatonin could play an important role in the ...
Chabra S - - 1997
We performed a retrospective review of all the infants diagnosed with trisomy 13 in our institution from 1982 to 1995 and evaluated the neurosonographic findings along with their clinical information and cytogenetic analysis. Nine babies were admitted with trisomy 13. Sonography of the head was performed on 4 patients, and ...
Baes M - - 1997
The cerebro-hepato-renal syndrome of Zellweger is a fatal inherited disease caused by deficient import of peroxisomal matrix proteins. The pathogenic mechanisms leading to extreme hypotonia, severe mental retardation and early death are unknown. We generated a Zellweger animal model through inactivation of the murine Pxr1 gene (formally known as Pex5) ...
Murch S H - - 1997
The intractable diarrhoeas of infancy present very major problems of clinical management. However, the conceptual importance of these conditions lies in the information that they may provide about normal small-intestinal function in humans: among such infants will be found the human equivalents of the 'knock-out' mice, in which targeted gene ...
Parish A R - - 1997
Sudden cardiac death is a leading cause of fatality in the industrially developed world. Sudden infant death syndrome, has not hitherto been regarded as the same disease. However, the 55% reduction in the recorded rate of death from sudden infant death syndrome following the removal of stress-related problems caused by ...
Santorelli F M - - 1997
We identified a single thymidine insertion at nucleotide position 5537 (T5537i) in the mitochondrial DNA transfer RNA gene for tryptophan in a family in which the proband had a progressive neurological disorder and his brother died in infancy of Leigh syndrome. Muscle biopsy from the proband showed subsarcolemmal proliferation of ...
Ponsonby A L - - 1997
The Centers for Disease Control in the United States have stated that studies to determine factors associated with failure to receive the first recommended dose of diphtheria-tetanus-pertussis are required. We examined an infant cohort to identify family and infant characteristics predictive of prompt first immunisation, to document changes in prompt ...
Perry J C - - 1997
Infant VT can be a devastating arrhythmia, with high mortality for those presenting with myocarditis, long QT syndrome, or cardiovascular collapse with rapid VT due to tumors. While management of these patients can be challenging and discouraging, other infants with wide QRS rhythms tend to follow a more benign course. ...
Schluter P J - - 1997
AIMS: This paper examined factors relating to the infants' place of domicile to see whether they increased the risk of sudden infant death syndrome (SIDS) beyond social and environmental effects previously published. METHODS: A case control study was undertaken in New Zealand between the years 1987-90. From all sudden infant ...
Raval D S - - 1997
Preeclampsia complicated by the HELLP syndrome is associated with poor maternal outcome; there is scant information on neonatal outcome. OBJECTIVE: To evaluate the outcome of infants born to mothers with HELLP syndrome. STUDY DESIGN: Chart review comparing perinatal variables and the clinical course of 23 infants born to mothers whose ...
David C M - - 1997
A study of the strikingly low incidence of sudden infant death syndrome in Eastern countries revealed significant differences in infant handling thought to have an etiological bearing; therefore this writer suggested that adoption of certain Eastern methods of nursing may reduce the incidence of sudden infant death syndrome. A dramatic ...
Chadduck W M - - 1997
One hundred and twenty-one consecutive patients presenting to the Children's National Medical Center with lambdoid positional molding (LPM) were reviewed. Clinical features included unilateral occipital flattening and alopecia and forward displacement of the ipsilateral ear, forehead, and maxilla. Head tilt and tightness of the ipsilateral sternocleidomastoid muscle were common. An ...
Kohlendorfer U - - 1997
The current study investigated whether sufficient attendance at prenatal and postnatal checks affects the risk of sudden infant death syndrome. A case-control study in the Tyrol enrolled 99 infants with sudden infant death syndrome that occurred between 1984 and 1994, and 136 randomly selected control cases. The risk of sudden ...
Brooke H - - 1997
OBJECTIVE: To investigate the relation between routine infant care practices and the sudden infant death syndrome in Scotland. METHODS: National study of 201 infants dying of the sudden infant death syndrome (cases) and 276 controls by means of home interviews comparing methods of infant care and socioeconomic factors. RESULTS: Sleeping ...
Church C - - 1997
The current literature regarding the standard and nonstandard therapies for children with autism is reviewed. A long term, comprehensive, individualized, multidisciplinary approach remains the best treatment. Physicians caring for the victims of child abuse are frequently asked to render an opinion regarding soft-tissue bruising. A review of the literature suggests ...
O'Connor R P - - 1997
A significant subpopulation of young infants who die suddenly (SIDS) often exhibit anomalies consistent with disruptions within the pineal-limbic system. We have hypothesized that sudden decreases in nocturnal melatonin by a specific range of geomagnetic activity would precipitate sudden infant death. A correlation of .90 was found between the numbers ...
Skinner J R JR Department of Cardiology, Bristol Royal Hospital for Sick Children, United - - 1997
To describe regional incidence, presentation, and outcome of idiopathic (familial) and Noonan syndrome related infant hypertrophic cardiomyopathy (HCM) between 1969 and 1994. Case series. Regional cardiac referral unit of the South West Region of England and south Wales, population approximately four million. 21 cases of idiopathic (or familial) HCM, and ...
Mage D T - - 1997
Sudden infant death syndrome, in 36 global data sets comprising 67378 postneonatal autopsied cases, has a male fraction of 0.612 which is significantly greater than the male birth fraction of 0.5122. Each of the sex ratios in the 36 data sets cannot be rejected as a random sample from a ...
Bolton P F - - 1997
OBJECTIVE: To determine whether and why obstetric complications are associated with autism. METHOD: Obstetric histories, obtained at maternal interview and coded as an optimality score (OS), were compared in two groups: 78 families containing an autistic proband (ICD-10 criteria) and 27 families containing a down syndrome (DS) proband. The OS ...
Portis R - - 1997
HELLP syndrome in the parturient (hemolysis, elevated liver enzymes, and low platelet count) is associated with poor maternal and fetal outcomes. Maternal mortality has been estimated to be as high as 24%. Patients with HELLP syndrome are also at greater risk of pulmonary edema, adult respiratory distress syndrome, abruptio placentae, ...
Wells J C - - 1997
Sudden infant death syndrome is characterized by a number of epidemiological features that have defied simple explanation. Overheating is believed to play a role in its causation. Overheating can be caused by changes in heat production, changes in insulation of the infant, or changes in the external environmental temperature. Risk ...
McLaughlin J F - - 1997
We report observations on children with the unusual combination of superior vena cava syndrome in infancy followed by communicating hydrocephalus. Following retrospective review of hospital discharges at a tertiary children's hospital, three children were identified in a 13-year period. Two term infants were treated with extracorporeal membrane oxygenation for pulmonary ...
Botet F - - 1997
The aim of this study was to determine the neonatal outcome in women with well-characterized antiphospholipid syndrome treated during pregnancy with low-dose aspirin. We compared 38 babies born after 36 pregnancies of 33 women diagnosed as having antiphospholipid syndrome with a group of 38 control infants matched for the same ...
Gürsel T - - 1997
Lysinuric protein intolerance (LPI) is an inborn error of amino acid transport characterized by a wide spectrum of clinical and biochemical abnormalities. Bone marrow hemophagocytosis in this disorder is an intriguing finding, present mostly in Italian patients. We report a 19-month-old Turkish infant with LPI, bone marrow hemophagocytosis, interstitial lung ...
Werner L A LA University of Washington, Department of Speech and Hearing Sciences, Seattle, - - 1996
Hearing loss commonly is associated with Down syndrome, but little is known about the development of auditory sensitivity in individuals with Down syndrome. This study had two objectives: 1) to determine whether an observer-based procedure can be used to assess the behavioral sensitivity of infants with Down syndrome, and 2) ...
Frost J D - - 1996
We describe successful treatment of an infant with progressive Langerhans cell histiocytosis (LCH) with allogeneic bone marrow transplantation (BMT), and discuss a chromosomal abnormality discovered in his LCH-affected tissue. A 4-month-old male infant with a seborrheic-appearing rash, respiratory collapse, and spontaneous pneumothorax is presented. LCH was diagnosed with primary involvement ...
Rahim R A - - 1996
Comparison of the frequency of occurrence of restriction fragment length polymorphisms in control human DNAs and DNAs from infants dying from sudden infant death syndrome has indicated no significant difference in the case of restriction fragment length polymorphisms associated with the heat shock protein genes hsp70 and hsp90. A highly ...
Itoh M - - 1996
We have observed sudden clinical death due to Fukuyama-type congenital muscular dystrophy (FCMD). In FCMD, brain abnormalities, such as polymicrogyria, leptomeningeal neuroglial heterotopia and abnormal course of the corticospinal tracts, are well known. We investigated the brainstem of 10 FCMD and 7 control cases. Among the control cases, 5 with ...
Huggle S - - 1996
We investigated the hippocampus and parahippocampal cortex of victims of sudden infant death syndrome and of age-matched infants dying acutely of known causes (non-sudden infant death syndrome controls). Tissue sections were investigated for the presence of neurons expressing signs of elevated levels of free radical using immunohistochemical markers for superoxide ...
Boyle F M - - 1996
Nonparticipants in epidemiological studies may differ in important respects from participants but the magnitude of this potential bias is rarely quantified. This study estimates the effect of nonparticipation on estimates of mental health problems following stillbirth, neonatal death or sudden infant death syndrome. Of 805 families approached, 512 (64 per ...
Kishnani P S - - 1996
The A to G point mutation at position 3243 of the mitochondrial DNA tRNALeu(UUR) gene is commonly found in patients with the syndrome of mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS). A male patient was referred at 7 months with failure to thrive, developmental delay, microcephaly and hypotonia since ...
Byard R W - - 1996
Infants with mandibular hypoplasia are at risk of sudden death from cardiorespiratory arrest secondary to upper airway obstruction. To evaluate diagnostic difficulties that may occur at autopsy in such infants, the autopsy files at the Adelaide Children's Hospital (ACH) for 36 years, 1959 to 1994, were reviewed. Eight cases were ...
Benito-León J - - 1996
Miller Fisher syndrome (MFS) is characterized by the triad of ataxia, areflexia and ophthalmoplegia. It is exceptional for infants to be involved. Two infants, aged 11 and 16 months, developed acute-onset MFS. Both patients had prodromal upper respiratory tract infection. Pupillary responses to light, strength and sensation modalities were preserved. ...
Shermak M A - - 1996
Otocephaly is a craniofacial syndrome with a constellation of findings consistent with symmetrically deficient development of the first branchial arch. Characteristically, those affected have ventrally displaced ears, microstomia, and an atrophic to absent mandible. Secondary to oropharyngeal incompetence, ventilatory, difficulties typically lead to the imminent death of these infants shortly ...
Sutton L - - 1996
The objectives of the investigation were (i) to study infants registered in a statewide audit of tertiary neonatal intensive care units in New South Wales, Australia in 1992 and who died, and (ii) to examine postmortem rates, quality of postmortem reports and compare clinical cause of death with postmortem report. ...
Denborough M - - 1996
Seven out of eight piglets which were susceptible to malignant hyperthermia (MHS) died when subjected to a heat challenge which was well tolerated by controls. The piglets which succumbed developed the classical clinical and biochemical changes of malignant hyperthermia before they died. These results show that overheating alone can trigger ...
Douglas A S - - 1996
OBJECTIVE: To determine whether seasonality of the sudden infant death syndrome persists now that rates have fallen, mostly after widespread adoption of the "face upwards" sleeping position. DESIGN: Monthly data on the sudden infant death syndrome during 1987-9 were compared for seasonality with those of 1991-3; rates were studied as ...
Kane A A - - 1996
OBJECTIVE: To verify and determine the cause of an increase in the referral of infants with plagiocephaly without synostosis (PWS) to a single tertiary craniofacial center. DESIGN: A chart review was performed for 269 infants with a diagnosis of PWS who presented to a single tertiary craniofacial center between 1979 ...
Vandenplas Y - - 1996
Regurgitation in infants is a common problem. Recent issues, such as the increased risk of sudden infant death in the prone sleeping position, the finding of persisting occult gastro-oesophageal reflux with feed thickeners, and the increasing awareness of the cost-benefit ratio of medications may challenge the currently recommended management approach. ...
Reid G M - - 1996
Dilation of the pulmonary arteries and increased pulmonary blood volume are recorded in sudden infant death syndrome and in infants living at low barometric pressures (high altitude). Low barometric pressure leads to chronic alveolar hypoxia (1,2). There is diversion and loss of body-fluid under conditions of microgravity (near-weightlessness) encountered in ...
Botash A S - - 1996
A review of the literature on child abuse continues to emphasize the importance of careful attention to physical findings. Children who are allegedly sexually abused very often have no abnormal physical findings, yet they may be subjected to repeat examinations in an attempt to document possible physical effects of the ...
Sparks D L - - 1996
Neuronal expression of the ALZ-50 epitope was investigated in hippocampus and medulla from infants dying of sudden infant death syndrome or known causes (controls). Hippocampal studies include data from 31 infants dying of known causes between 32 weeks' gestation and 16 months postpartum and 46 infants who died of sudden ...
D'Apolito K C - - 1996
Substance abuse among pregnant women has become a national health issue. As a result of the increase in maternal consumption of illicit drugs during pregnancy, many more infants are experiencing signs and symptoms of withdrawal during the immediate newborn period. In many instances, pharmacologic management is required to alleviate the ...
Lucena J - - 1996
The ependyma may befall a variety of pathogenic noxae during fetal life, resulting in histological changes which may persist after birth but are without clinical manifestations. Eight of a series of 19 children who died suddenly and unexpectedly, where no explanation as to the cause of death was found at ...
Donahoe P K - - 1996
Infants and children with ambiguous genitalia pose challenging diagnostic and therapeutic issues for the clinician. Success depends on rapid and precise diagnosis, appropriate gender assignment, proper medical therapy, and meticulous surgical technique. A well-trained multispecialty clinical team is essential. The major disease categories include chromosomal abnormalities, excessive androgen syndromes, and ...
Lecoq I - - 1996
Medium-chain acyl-CoA dehydrogenase deficiency is the most common genetic defect of hepatic fatty acid oxidation. Clinical signs are somnolence and lethargy potentially leading to coma. Death occurs during the first attack in about 20% of cases, suggesting sudden infant death syndrome. A point mutation (adenine to guanine at position 985) ...
Stockwell E G - - 1996
"This paper presents the results of an ecological analysis of the relationship between infant mortality and economic status in a metropolitan aggregate comprised of six of the larger cities in Ohio covering the years 1979-81 and 1989-91.... Results of the analysis revealed, first of all, that there continues to be ...
Scragg R K - - 1996
BACKGROUND: There is evidence that the risk of sudden infant death syndrome is lower among ethnic groups in which parents generally share a room with the infant for sleeping. We investigated whether the presence of other family members in the infant's sleeping room affects the risk of the sudden infant ...
Hansen M - - 1996
We report extreme expression of Treacher Collins syndrome in an infant with arhinia, anotia, absent zygomatic bones, hypoplastic mandibular rami, and bilateral coloboma of iris, choroid plexus, and optic nerves. The Treacher Collins phenotype was mildly expressed in the mother and moderately in the sister. The father had no signs ...
George M - - 1996
Gastrointestinal degradation of urea might, according to a new hypothesis, have consequences for the regulation of acid-base balance as well as control of breathing during infancy. Thirteen infants were investigated from their first few days of life to the age of 6 months by collecting faecal samples at the age ...
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