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Verbeek Renate J - - 2011
Aim  Our aim was to compare the effect of prenatal endoscopic with postnatal myelomeningocele closure (fetally operated spina bifida aperta [fSBA]) versus neonatally operated spina bifida aperta [nSBA]) on segmental neurological leg condition. Method  Between 2003 and 2009, the fetal surgical team (Department of Obstetrics, University of Bonn, Germany) performed ...
Samra Nashwa M - - 2011
Objective: We investigated the effect of kangaroo mother care (KMC) on the duration of phototherapy of jaundiced neonates. Methods: Fifty Egyptian newborns hospitalized for jaundice were investigated through a prospective observational study to determine whether intermittent KMC would reduce the duration of phototherapy required. Results: The babies who received KMC ...
Bernis Cristina - - 2011
OBJECTIVES: Previous studies generally agree that in Homo sapiens births without medical intervention occur mostly at night, although with a less accentuated pattern than in other primate species. The present study has three main objectives: (a) to establish the hourly pattern of births in a modern medicalized population, (b) to ...
Kirton Adam - - 2011
Background:Neonatal arterial ischemic stroke (AIS) has emerged as a leading cause of perinatal brain injury, cerebral palsy, and lifelong disability. The pathogenesis is poorly understood, which limits the development of treatment and prevention strategies. Multicenter studies must define epidemiology, risk factors, treatment practices, and outcomes to advance clinical trials and ...
Bonamy Anna-Karin Edstedt - - 2011
BACKGROUND: <0.001). Among mothers to very SGA infants, the hazard ratio of CVD ranged from 1.38 (95% confidence interval 1.15-1.65) to 3.40 (95% confidence interval 2.26-5.11) in mothers to term and very preterm infants, respectively.Conclusions-Delivery of a preterm or SGA infant is associated with later life maternal hospitalization or death ...
Lasky Tamar - - 2011
BACKGROUND: Dobutamine and dopamine are off-patent drugs prioritized by the National Institute of Child Health and Human Development and US Food and Drug Administration for further study under the Best Pharmaceuticals for Children Act. Both agents are used to manage cardiac insufficiency in preterm neonates and are subject to controversy ...
O'Dwyer Vicky - - 2011
OBJECTIVE: To review maternal mortality in a large stand-alone maternity hospital in a European city and to determine whether the increased cesarean rate was associated with an increase in maternal deaths. METHODS: The details of maternal deaths at Coombe Women and Infants University Hospital, Dublin, Ireland, as published in the ...
Schaible T - - 2011
Cytokines play an important role in immune regulation and fetal lung development. The systemic inflammatory response in newborns with congenital diaphragmatic hernia (CDH) has not been characterized so far. We compared various concentrations of cytokines in serum from newborns with CDH and in healthy term neonates. We analyzed cytokine patterns ...
Salihoğlu Ozgül - - 2011
Background:  Arterial blood pressure (BP) is one of the four vital signs that reflect cardiovascular status in neonates. The present study aimed to obtain BP percentiles among healthy, singleton, liveborn neonates between 34-43 weeks of gestation (WG) who were less than 1 hour old. Methods:  BP measurements were taken after ...
Murdoch Marlies R - - 2011
Murdoch M.R. & Franck L.S. (2011) Gaining confidence and perspective: a phenomenological study of mothers' lived experiences caring for infants at home after neonatal unit discharge. Journal of Advanced Nursing 00(0), 000-000 ABSTRACT: Aim.  This paper is a report of a descriptive study of mothers' experiences in caring for preterm or ...
Kuipers Remko S - - 2011
INTRODUCTION: There is no information on the whole body fatty acid (FA) contents of preterm or term infants, although scattered information on the FA-composition of many organs is available. MATERIAL AND METHODS: We collected data on the weights, lipid contents and FA-compositions of the quantitatively most important fetal organs of ...
Harpavat Sanjiv - - 2011
Healthy infants are thought to acquire biliary atresia (BA) in the first weeks of life. Because those diagnosed earlier have better outcomes, we were interested in determining the earliest time BA could be detected. We started by examining the immediate postnatal period, hypothesizing that newborns would not yet have acquired ...
Hole Michael K - - 2012
Objective. The WHO estimates that 99% of the 3.8 million neonatal deaths occur in developing countries. Neonatal resuscitation training was implemented in Namitete, Malawi. The study's objective was to evaluate the training's impact on hospital staff and neonatal mortality rates. Study Design. Pre-/postcurricular surveys of trainee attitude, knowledge, and skills ...
Thomson T - - 2011
Objective:To determine the effect of neonatal and maternal blood group on the mortality risk from necrotizing enterocolitis (NEC).Study Design:Retrospective chart review of all neonates admitted to the neonatal intensive care unit over 24 years. Data on birth date, gestational age, maternal/neonatal blood group, number of transfusions, and survival time (defined ...
Kaur S - - 2011
Objective:To evaluate efficacy of predischarge transcutaneous bilirubin (TcB) measurement and clinical risk assessment in predicting hyperbilirubinemia needing treatment.Study Design:A diagnostic test was performed in a prospective cohort study conducted at a teaching hospital in North India. Subjects included healthy neonates with a gestation period of 35 weeks or birth weight ...
Saini S S - - 2011
Objective:To compare the proportion of correct placements (POCP) between 'two-fingers' and 'two-thumbs' techniques of chest compression among neonates of various gestations.Study Design:Two-fingers and two-thumbs spans of 32 adult rescuers were individually compared with the inter-nipple line to sterno-xiphoid junction distance of 39 neonates. 'Correct placement' was defined if two-fingers/two-thumbs span ...
Unger Annemarie - - 2011
Prior studies have shown an increased vulnerability among males to adverse outcomes during the postnatal period. Most children exposed to opioids and other medications in utero develop neonatal abstinence syndrome (NAS), yet individual predisposition for NAS is poorly understood. This investigation examined the role of neonatal sex in the postnatal ...
Sutcuoglu Sumer - - 2011
ABSTRACT Aim: To evaluate the knowledge of mothers on neonatal jaundice. Methods: This study was conducted on 161 mothers who had given birth to healthy newborns at Izmir Aegean Gynecology and Obstetrics Hospital between January? April 2010. A questionnaire was used to assess the mothers? knowledge on neonatal jaundice. Knowledge ...
Berglund Sophie - - 2011
Abstract Aim: To propose suggestions for improvements in care based on conclusions from studies on low Apgar scores and substandard care during labor. Setting and patients: Studies on infants with low Apgar scores in a general obstetric population 2004?2006 and claims for financial compensation on the behalf of infants, based ...
Kanda Eriko - - 2011
Abstract Objective To assess the risk factors for abnormal fetal growth in patients with pregestational diabetic mellitus (DM). Methods A retrospective study was performed in 336 patients with pregestational DM. Small-for-gestational-age (SGA) and large-for-gestational-age (LGA) infants were defined as newborns with birth weights < 10(th) percentile and > 90(th) percentile, ...
Følsgaard Nilofar V - - 2011
Rationale Heredity from mother or father may impact differently in complex diseases such as atopy. Maternal atopy is a stronger risk factor than paternal atopy for the development of atopy in the offspring. We hypothesized that mother's and father's atopy would have a differential imprinting on the cytokines and chemokines ...
Dukhovny D - - 2012
Moderately premature infants, defined here as those born between 30⁰/₇ and 34⁶/₇ weeks gestation, comprise 3.9% of all births in the United States and 32% of all preterm births. Although long-term outcomes for these infants are better than for less mature infants, morbidity and mortality are still substantially increased in ...
Nga Nguyen Thu - - 2011
Aim:  To ascertain the causes of neonatal death in a province in northern Vietnam and analyse their distribution over age at death, birth weight and place of delivery. Methods:  Verbal autopsy interviews using a questionnaire derived from WHO standard and adapted to Vietnamese conditions was performed on all neonatal deaths ...
Vijayasekaran D - - 2011
OBJECTIVE: To analyse the indications, safety and outcome of flexible fiberoptic bronchoscopy (FOB) in neonates. METHODS: This descriptive study was conducted in Level III neonatal unit (ICH, Chennai) and included 84 neonates with various respiratory problems admitted over a 3 y period. RESULTS: The indications included stridor (18%), persistent radiological ...
Johnson Lynn H LH Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. - - 2012
To assess the relationship between umbilical cord blood magnesium concentration and level of delivery room resuscitation received by neonates. This was a secondary analysis of a controlled fetal neuroprotection trial that enrolled women at imminent risk for delivery between 24 and 31 weeks' gestation and randomly allocated them to receive ...
Osanan Gabriel Costa - - 2011
Abstract Introduction: Alloimmunization is the main cause of fetal anemia. There are not many consistent analysis associating antenatal parameters to perinatal mortality in transfused fetuses due to maternal alloimmunization. The study aimed to determine the prognostic variables related to perinatal death. Material and Methods: a cohort study analyzed 128 fetuses ...
Walker Mark C - - 2011
Objective: The Ottawa and Kingston (OaK) Birth Cohort collected data on maternal and infant genetic and epidemiologic variables in order to (1) explore the association between folate supplementation or thrombophilias and adverse, placenta-mediated pregnancy outcomes; (2) create a biobank of maternal and infant biological and genetic samples; and (3) stimulate ...
Chung Sung-Hoon SH Department of Medicine, Kyung Hee University Graduate School, Seoul, - - 2011
Neonatal mortality rate (NMR) or infant mortality rate (IMR) are the rate of deaths per 1,000 live births at which babies of either less than four weeks or of one year of age die, respectively. The NMR and IMR are commonly accepted as a measure of the general health and ...
Jansson L M LM Johns Hopkins University School of Medicine, Department of Pediatrics, Baltimore, MD 21224, USA. - - 2012
It is suspected that there is a continuum of impairment among prenatally drug-exposed infants, such that opioid and/or poly-drug exposure confers the highest risk for adverse neonatal outcomes than other classes of substances or single substance exposures. Suitable control groups are difficult to identify. This study compared fetal neurobehavioral development ...
Berglund Sophie - - 2012
The authors had previously found flaws in resuscitation after severe neonatal asphyxia in cases selected on the grounds of suspected malpractice and financial compensation claims. The aim of the present study was to evaluate neonatal resuscitation in the general obstetric population in a setting with skilled attendance at birth. Observational ...
Goldenberg Robert L - - 2011
A comprehensive classification system for preterm birth requires expanded gestational boundaries that recognize the early origins of preterm parturition and emphasize fetal maturity over fetal age. Exclusion of stillbirths, pregnancy terminations, and multifetal gestations prevents comprehensive consideration of the potential causes and presentations of preterm birth. Any step in parturition ...
Goyal Tarang - - 2011
OBJECTIVE: To analyse the incidence of dermatoses in neonates, stress the importance of simple noninvasive diagnostic procedures with perspective to actual need of active intervention. METHODS: Forty four neonates with vesicobullous lesions in Departments of Dermatology and Pediatrics were evaluated with respect to diagnosis, required treatments and follow ups. RESULTS: ...
Pitcher Julia B - - 2011
Despite advances in knowledge and technology, accurate prediction of later neuromotor outcomes for infants born preterm remains somewhat elusive. Here we review some of the most recent findings regarding the differential effects of preterm birth and suboptimal fetal growth on neurodevelopment. Evidence from transcranial magnetic stimulation studies is presented that ...
Hirota Yasushi - - 2011
Although preterm delivery is a major global health issue, its causes and underlying mechanism remain elusive. Using mutant mice, mimicking aspects of human preterm birth, we show here that uterine decidual senescence early in pregnancy via heightened mammalian target of rapamycin complex 1 (mTORC1) signaling is a significant contributor of ...
Kuleva M - - 2012
To establish a correlation between prenatal ultrasound findings and postnatal outcome in neonates with gastroschisis (GS). Retrospective case-control study. Prenatal ultrasound reports, labour and neonatal intensive care unit notes, and paediatric surgical clinic records were reviewed. Neonates with an antenatal diagnosis of isolated GS. The neonates were divided into two ...
Fransson Emma - - 2011
Citation Fransson E, Dubicke A, Byström B, Ekman-Ordeberg G, Hjelmstedt A, Lekander M. Negative emotions and cytokines in maternal and cord serum at preterm birth. Am J Reprod Immunol 2011 Problem  This study investigates whether affectivity differs between mothers delivering preterm and term and whether maternal and umbilical cord serum ...
Coman David - - 2011
Extended newborn screening (ENBS) with the use of tandem mass spectrometry technology is well established in all Australian states and in New Zealand. ENBS has afforded a marked reduction in morbidity and mortality in select conditions such as medium-chain acyl-CoA dehydrogenase deficiency. While this technology has been of great benefit ...
Oncel Mehmet Yekta - - 2011
PURPOSE: Folate is an essential micronutrient for fetal development because of its role in de novo synthesis of DNA. The aim of this study was to compare neonatal serum folate levels of babies born to smoking and non-smoking mothers. METHODS: Infants of consenting pregnant mothers presenting at ≥37 weeks of gestation ...
Boutsikou T - - 2011
Maternal/foetal morbidity/mortality consequent to uterine rupture, placenta previa/increta and stillbirth may occur in repeat caesarean section (CS). Elective CS before 39 weeks increases respiratory complications, hypoglycaemia, sepsis and intensive care unit admissions. Different gut colonization in neonates born by CS accounts for increased incidence of food allergy, asthma and possibly ...
Plummer Christopher P - - 2011
Aim:  This study aimed to compare maternal and neonatal outcomes after no tocolysis, short-term tocolysis (≤48 h), and maintenance tocolysis (>48 h). Methods:  This was a retrospective study, conducted from January 2007 to June 2008, of vaginal preterm deliveries admitted to the neonatal intensive care unit (NICU) between 23 and 36 weeks of ...
Grivell Rosalie M - - 2011
Objective. To evaluate maternal and neonatal outcomes associated with birth at term by week of gestational age and also by onset of labor. Design. Cohort study. Setting. A state-wide perinatal outcome database. Population. 28 626 women with spontaneous onset of labor, induction of labor for recognized indications and induction of ...
Ugiagbe Ezekiel Enoghama - - 2011
Abstract Background: Postmortem examination remains the gold standard for the correct diagnosis of many diseases and for unraveling unexplained causes of death. This paper reports on the poor utilization of autopsy services and encourages parents/caregivers and practitioners to perform postmortem examinations on deceased neonates. Methods: The records of 1093 neonates ...
Martinez-Biarge Miriam - - 2011
OBJECTIVE: To examine perinatal morbidity and rate of hypoxic-ischemic encephalopathy in infants exposed to intrapartum sentinel events. STUDY DESIGN: Retrospective cohort study from 2000-2005. Perinatal mortality, perinatal morbidity and rate of hypoxic-ischemic encephalopathy were compared in 3 groups of infants exposed to different risk factors for perinatal asphyxia (sentinel events, ...
Lavezzi Anna Maria - - 2011
The area postrema is a densely vascularized small protuberance at the inferoposterior limit of the fourth ventricle, outside of the blood-brain barrier. This structure, besides to induce emetic reflex in the presence of noxious chemical stimulation, has a multifunctional integrative capacity to send major and minor efferents to a variety ...
Crump Casey - - 2011
To determine whether preterm birth is associated with epilepsy in a national cohort of adults aged 25-37 years. We conducted a national cohort study of 630,090 infants born in Sweden from 1973 through 1979, including 27,953 born preterm (<37 weeks), followed from 2005 to 2009 for 1) hospitalization for epilepsy ...
Strasheim Esedra - - 2011
Neonatal communication intervention is important in South Africa, which has an increased prevalence of infants born with risks for disabilities and where the majority of infants live in poverty. Local literature showed a dearth of information on the current service delivery and roles of speech-language therapists (SLTs) and audiologists in ...
Phelan Jeffrey P - - 2011
To estimate whether term neonates with acute intrapartum hypoxic ischemic encephalopathy and permanent brain injury satisfied the criteria for causation of cerebral palsy developed by the Task Force on Neonatal Encephalopathy and Cerebral Palsy. In this descriptive study, patients in the case group were obtained from a registry of singleton, ...
Iams Jay D - - 2011
Despite the increase in indicated late preterm births, spontaneous preterm labor and preterm premature rupture of the fetal membranes are the most common antecedent diagnoses leading to births between 34-0/7 and 36-6/7 weeks of gestation. Regional and institutional variation in the rates of late spontaneous preterm birth suggests that there ...
Zbinden A - - 2011
Our aim was to evaluate the clinical impact of routine amniotic fluid and neonatal surface swab microbiology at Caesarean section.Microbiology data from 1 537 neonates delivered by Caesarean section were analysed in the light of clinical outcome.1 340 (87%) neonates had non-pathogenic bacteria or negative culture results from both amniotic fluid and ...
Deeks Emma D - - 2011
17 α-hydroxyprogesterone caproate is a synthetic progestin of which there is now a US FDA-approved formulation available for intramuscular administration (Makena™) to reduce the risk of preterm birth. Intramuscular 17 α-hydroxyprogesterone caproate (identical in formulation and manufacturing process to Makena™, thus hereafter referred to as Makena™) 250 mg once weekly, initiated ...
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