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Wirbelauer Johannes - - 2010
OBJECTIVES: A systemic inflammatory response after intrauterine funisitis is assumed to be an important priming factor for acute and chronic pulmonary morbidity and neurological impairment in premature infants. Fetal lymphocytes and monocytes modulate the primary immune response. Genetic regulation of the cytokine-mediated process is partially known. The objective of our ...
Pedersen L J - - 2011
The primary aim of the present study was to investigate whether the same piglet traits contributed to the same causes of neonatal piglet mortality in crates (CT) and pens (PN). Gilts originating from 2 distinct genetic groups that differed in breeding value for piglet survival rate at d 5 (SR5) ...
Bueno C - - 2011
Infant acute lymphoblastic leukemia (ALL) involving mixed-lineage leukemia (MLL) fusions has attracted a huge interest in basic and clinical research because of its prenatal origin, mixed-lineage phenotype, dismal prognosis and extremely short latency. Over 90% of infant ALLs are pro-B ALL harboring the leukemic fusion MLL-AF4. Despite the fact that ...
Tan Ki-Wei - - 2010
Juvenile xanthogranuloma is usually a benign condition mainly seen in infants and children. It frequently presents as asymptomatic discrete papules on the head, trunk, and limbs. Extracutaneous manifestations, most commonly ocular, are rare but may be associated with significant morbidity. The etiology of juvenile xanthogranuloma is uncertain, although the occurrence ...
Abler Sylvie - - 2011
Background Admission weight to neonatal intensive care units is used in several diagnosis related group (DRG) systems to assess reimbursement by health insurance programs for premature infants. Modifications of admission weights could significantly affect reimbursement in either direction. Objective Whether the introduction of the German DRG system in 2004 influenced ...
Saiki Tolulope - - 2011
The vulnerability of prematurely born infants to sudden infant death syndrome (SIDS) in the prone position might be explained by a reduced ability to respond to a stress, such as hypercarbia, in that position; our objective, therefore, was to further explore the influence of position on the response to a ...
Garten Lars - - 2011
Preterm newborn infants may suffer laryngeal injuries after multiple intubations and long-term mechanical ventilation. Former studies have focused on acute laryngeal injuries diagnosed by endoscopy, performed within the neonatal period. This retrospective case-control study aims to investigate the prevalence and clinical risk factors for voice disorders in former very low-birth-weight ...
Taylor Sarah N - - 2010
Historically, in very low-birth-weight infant care, nutritional support was delayed during the first postnatal days because of fear of toxicity and harm with immature metabolic systems and intestinal function. Recent evidence demonstrates that early nutritional support is not only safe but likely necessary to optimize infant growth and neurodevelopment. In ...
Conway-Orgel Margaret - - 2010
Primum non nocere, a saying in Latin that means "first, do no harm," is a phrase neonatal clinicians should keep in mind when initiating or suggesting treatment. In the "golden hour" of resuscitation of the very low-birth-weight infant, team members assess multiple parameters of the infant's vital signs, with a ...
Tersigni Chiara - - 2011
Objective. To report about a case of complicated late postpartum eclampsia where neonatal low birth weight could be considered a predictive factor of placental sufferance. Methods. A 25-year-old woman, without medical or familiar history for hypertension or cerebrovascular diseases, underwent a normal spontaneous delivery with neonatal birth weight of 2340 ...
D'Angio Carl T CT University of Rochester School of Medicine and Dentistry, Rochester, NY, USA. - - 2010
The heptavalent pneumococcal CRM197 conjugate vaccine (PCV-7) has been incompletely studied in very-low-birth-weight (< or =1500 g) infants. To assess PCV-7 immunogenicity in very-low-birth-weight, premature infants. We hypothesized that the frequency of postvaccine antibody concentrations > or =0.15 microg/mL would vary directly with birth weight. This was a multicenter observational ...
Bidegain Margarita - - 2010
Intravenous vasopressin at 0.01 to 0.04 units/kg/h increased median mean blood pressure from 26 mm Hg (range 18-44) to 41 mm Hg (range 17-90) by 12 hours of infusion (P=.002) and allowed weaning of catecholamines in a group of extremely low birth weight infants with refractory hypotension.
Beardsall Kathryn K Department of Paediatrics, University of Cambridge, Addenbrooke's Hospital NHS Trust, Cambridge, UK. - - 2010
To investigate the prevalence and determinants of hyperglycemia in the preterm population, as part of the Neonatal Insulin Therapy in Europe (NIRTURE) Trial. We conducted prospective cohort analyses of continuous glucose monitoring data from control infants participating in an international randomized controlled trial. Data were collected from 188 very low ...
Wilson Ann L - - 2010
Currently in South Dakota, multiples comprise between three and four percent of all births and are increasingly contributing to annual cohorts of newborns. In recent years, multiples contribute to between 20 and 30 percent of all low-birth-weight newborns. In 2008, almost 35 percent of all very low-birth-weight infants were multiples. ...
Ligi Isabelle - - 2010
Low birth weight infants, in particular those born preterm, have been shown to develop increased arterial blood pressure and hypertension at adulthood. Three main systems are involved in the developmental programming of hypertension: the kidney, the neuroendocrine system, and the vascular tree. This review focuses on vascular dysfunction and discusses ...
Indredavik Marit S - - 2010
OBJECTIVE: To study perinatal risk factors for psychiatric symptoms in adolescents born preterm with very low birth weight or at term, but small for gestational age (GA). METHOD: Mental health was assessed in 65 adolescents born with very low birth weight (VLBW) (birth weight < or = 1500 g), 59 ...
Miller Nichole E - - 2010
The generalized anatomic and physiologic immaturity of preterm infants of very low birth weight (VLBW) (<or=1,500 g) and extremely low birth weight (ELBW) (<or=1,000 g) places them at high risk for death or associated negative sequelae, including chronic lung disease of infancy (CLDI). The standard treatment for pulmonary immaturity, mechanical ...
Rees Clare M - - 2010
INTRODUCTION: Proponents of peritoneal drainage (PD) hypothesize that it allows stabilization before laparotomy. We examined this hypothesis by comparing clinical status before and after either PD or primary laparotomy (LAP). METHODS: In an ethically approved, international, prospective randomized controlled trial (2002-2006), extremely low birth weight (<1000 g) infants with pneumoperitoneum ...
Ooki Syuichi S Department of Health Science, Ishikawa Prefectural Nursing University, Ishikawa, Japan. - - 2010
Despite the rapid increase in the rate of multiple births due to the growth of reproductive medicine, there have been no epidemiologic studies of the secular trends in the impact of multiple births on the rates of low-birth-weight and preterm deliveries in Japan. Japanese vital statistics for multiple live births ...
Puch-Kapst Kathrin - - 2009
OBJECTIVE: We determined the frequency and estimated effective radiation dose (E) from conventional diagnostic radiographs for infants who had birth weight of <or=1500 g (very low birth weight [VLBW] infants) and were treated in a NICU. METHODS: Entrance skin doses were experimentally measured for all standard weight-dependent exposure settings. For ...
Noori Shahab - - 2009
Little is known about the effect on clinically relevant outcomes of the complex hemodynamic changes occurring during adaptation to extrauterine life in preterm neonates, particularly in very low birth weight neonates. As cardiovascular adaptation in this extremely vulnerable patient population is complicated by immaturity of all organ systems, especially that ...
Khattak A Z - - 2010
OBJECTIVE: To measure systemic silver absorption when using silver-impregnated alginate central catheter dressings in very low birth weight (VLBW) neonates and to monitor blood stream infection. STUDY DESIGN: Fifty infants were enrolled in a prospective, randomized controlled trial lasting 28 days. Each patient was assigned to standard dressing or silver ...
Sir-Petermann Teresa - - 2010
Context: We previously demonstrated that low birth weight (BW) infant girls show increased serum anti-M?llerian hormone (AMH) concentrations and poststimulated estradiol levels compared to normal-BW infants, suggesting an altered follicular development. However, the impact of high BW on reproductive function is less known. Objective: To evaluate the effect of BW ...
Takahashi S - - 2010
OBJECTIVE: Superior vena cava (SVC) flow is used as an index for evaluating systemic blood flow in neonates. Thus far, several reports have shown that low SVC flow is a risk factor for intraventricular hemorrhage (IVH) in the preterm infant. Therefore, it is likely to be a useful index in ...
Luyckx Valerie A - - 2009
Epidemiological studies show a strong association between low birth weight and hypertension, renal, and cardiovascular disease, especially after catch-up growth. Senescence is an important contributor to the progression of chronic disease. Developmentally programmed premature senescence may be a link among low birth weight, catch-up growth, and adult disease. Low birth ...
Bieda Amy - - 2009
Extremely low birth-weight infants are prone to fluid and electrolyte imbalance due to multiple etiologies. Hypernatremia can occur in this gestational age group during the first week of life. One therapy that many NICUs initiate to treat hypernatremia is enteral sterile water feeds (SWFs). The use of free water is ...
Hayes Breda - - 2009
OBJECTIVE: To examine whether low birth weight (LBW) children are at greater risk for behavioural and emotional problems than normal birth weight children. METHODS: Electronic databases (PubMed, Google) were searched. Key search terms (LBW, emotional behavioural outcome) were used to identify possible studies. Selection of studies was limited to those ...
Lohmeier Klaus - - 2009
Pleural empyema is rarely seen in the newborn period. Here we report the first case of exclusive and successful conservative management of pleural empyema in an extremely low birth weight infant. Chest drainage or percutaneous aspiration was not feasible. Noninvasive treatment might represent an acceptable option in premature infants.
Kawada Mayumi - - 2009
We evaluated the use of micafungin as a prophylaxis in very-low-birth-weight infants. Micafungin was first administered to 25 very-low-birth-weight infants 12 to 24 hours after birth at a dose of 1 mg/kg/d. the apparent volume of distribution, the apparent elimination rate constant, the elimination half-life, and the total body clearance ...
Hyman Sharon J - - 2009
Endocrine disorders are common in infants in the neonatal ICU. They often are associated with prematurity, low birth weight or very low birth weight, and small size for gestational age. They also frequently occur in infants who are critically ill or stressed. This article describes the most common conditions and ...
Nascimento Luiz Fernando C - - 2009
The aim of this study was to assess the association between prenatal exposure to air pollutants and low birth weight in a medium-sized city. An ecological study was performed, using live birth data from São José dos Campos, São Paulo State, Brazil. The environmental data were obtained from the São ...
Were F N - - 2009
BACKGROUND: Infant mortality remains high in many developing countries in which the contribution of deaths among infants born very low birth weight (VLBW) may be considerable. This contribution has however not been quantified in most such countries. This paper explores a model that can be used in this respect. OBJECTIVE: ...
Nkansah-Amankra Stephen - - 2010
Effects of income inequality on health and other social systems have been a subject of considerable debate, but only a few studies have used multilevel models to evaluate these relationships. The main objectives of the study were to (1) Evaluate the relationships among neighborhood income inequality, social support and birth ...
Sharathkumar Anjali Alatkar - - 2009
Aortic arch thrombosis (AAT) is a potentially life threatening condition in neonates. We report 3 neonates with AAT and complete occlusion of a unilateral internal carotid artery with multiple cerebral infarcts. Multidisciplinary input led to deferral of thrombolytic therapy and surgical thrombectomy owing to the potential risk of hemorrhage within ...
Spector Logan G - - 2009
The risk of hepatoblastoma is strongly increased among children with very low birth weight (<1500 g). Because data on very low birth weight and other childhood cancers are sparse, we examined the risk of malignancy with very low birth weight in a large data set. We combined case-control data sets ...
Bühler Karina Elena Bernardis - - 2009
The performance of very low birth weight preterm infants, in terms of cognition and expressive language, was analyzed and compared with that of term infants with the Protocol for Expressive Language and Cognition Development Observation (PELCDO). The study involved 12 very low birth weight preterm infants and 20 term infants, ...
Partington Susan N - - 2009
CONTEXT: Teenagers are more likely than older women to have a low-birth-weight infant or a preterm birth, and the risks may be particularly high when they have a second birth. Identifying predictors of these outcomes in second teenage births is essential for developing preventive strategies. METHODS: Birth certificate data for ...
Amarilyo Gil - - 2009
Thirty-one consecutive infants <1000 g at birth were intubated according to Tochen's rule; placement was verified/modified after auscultation and by radiology. Depth measurements were by caliper and radiology. Tochen's rule alone would lead to inadequate tube placement in 47% of infants. Auscultation allows adequate placement in only three-fourths of patients.
Bull Marilyn J - - 2009
Safe transportation of preterm and low birth weight infants requires special considerations. Both physiologic immaturity and low birth weight must be taken into account to properly position such infants. This clinical report provides guidelines for pediatricians and other caregivers who counsel parents of preterm and low birth weight infants about ...
Walter Eric C - - 2009
The proportion of low and very low birth weight births is increasing. Infants and children with a history of low and very low birth weight have an increased risk of respiratory illnesses, but it is unknown if clinically significant disease persists into adulthood. To determine if a history of low ...
Rougé Carole - - 2009
BACKGROUND: Although recent reports suggest that supplementation with probiotics may enhance intestinal function in premature infants, the mechanisms are unclear, and questions remain regarding the safety and efficacy of probiotics in extremely low-birth-weight infants. OBJECTIVE: The objective was to evaluate the efficacy of probiotics on the digestive tolerance to enteral ...
Janér Joakim - - 2009
INTRODUCTION: Endostatin is an antiangiogenic growth factor. Together with proangiogenic growth factors it acts to shape the developing vasculature. Dysregulation of angiogenesis is a component in the pathogenesis of bronchopulmonary dysplasia. OBJECTIVE: Our goal was to study whether the concentration of circulating endostatin at birth is associated with the development ...
Procianoy Renato S - - 2009
Prematurity and intrauterine growth restriction are associated with neurodevelopment delay. A prospective cohort study included all 96 very low birth weight infants discharged from our neonatal unit from November 2003 to June 2005. The authors compared 41 appropriate and 55 small for gestational age very low birth weight infants' neurodevelopment ...
Ziegler Ekhard E - - 2009
In the past, initiation of nutritional support of very low birth weight (VLBW) infants was delayed because of concerns about the safety of nutrient administration. This contributed to the impairment of neurocognitive development that these infants often display later in life. Today there is consensus that nutritional support of VLBW ...
Golab Hanna D - - 2009
Extensive variations of colloid osmotic pressure (COP) measured in the priming as well as during infant cardiopulmonary bypass motivated us to audit clinical and laboratory data to identify the risk factors for low COP at the end of bypass. Data of 73 consecutive infant patients with body weight <10 kg, ...
Lee Tzu-Ying - - 2009
AIM: The purpose of this study was to explore the paternal role of fathers of very low birth weight infants during their first year of life. BACKGROUND: Following birth, very low birth weight infants often require extended hospitalisation and long-term care. The birth experience and the infant's hospitalisation often overwhelm ...
Yoshizawa Yukihiro - - 2009
BACKGROUND: The degree of periventricular white matter echodensity in preterm infants has been utilized as a sign of the early ultrasonographic appearance of periventricular leukomalacia, and this has been called periventricular echodensity (PVE). OBJECTIVES: The aim of this study was to quantitatively measure PVE utilizing a new method which is ...
van den Berg Anemone - - 2009
OBJECTIVE: Very low birth weight (VLBW) infants receiving glutamine-enriched enteral nutrition may present with a lower infection rate, which may result from enhanced antimicrobial innate or Th1 cytokine responses. We investigated whether glutamine-enriched enteral nutrition in VLBW infants increased these cytokine responses following in vitro stimulation of whole blood cells. ...
Batton Beau - - 2009
OBJECTIVE: To compare neurodevelopment (ND) in 3 cohorts of extremely preterm infants: untreated with normal blood pressure (BP), untreated with low BP, and treated with low BP. STUDY DESIGN: We conducted a retrospective study of infants 23 to 25 weeks gestation. Low BP was defined as >or=3 mean arterial pressures ...
Fleming P - - 2008
Substantial variation exists in the use of a number of post natal interventions and procedures between neonatal intensive care units. This study examined current practice in the management of commonly encountered problems in very low and extremely low birth weight infants in the eight regional units in Ireland, and was ...
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