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Cui Yinqiu Y School of Life Sciences, Jilin University, Changchun 130012, People's Republic of China Research Center for Chinese Frontier Archaeology, Jilin University, Changchun 130012, People's Republic of - - 2015
The Yuan Dynasty (AD 1271-1368) was the first dynasty in Chinese history where a minority ethnic group (Mongols) ruled. Few cemeteries containing Mongolian nobles have been found owing to their tradition of keeping burial grounds secret and their lack of historical records. Archaeological excavations at the Shuzhuanglou site in the ...
Mukherjee Ayan A a Animal Genomics Lab, Animal Biotechnology Center , National Dairy Research Institute , Karnal , - - 2015
The removal of crossbred bulls from semen collection programs due to the production of poor quality semen causes substantial monetary losses to the dairy industry. Seminal quality, a quantitative trait, is greatly influenced by genome level variations. Deletion and/or duplication of Y chromosomal genes and subsequent changes in gene copy ...
Hamid Ahmed B AB Jena University Hospital, Institute of Human Genetics, Friedrich Schiller University, Kollegiengasse 10, Jena, D-07743, - - 2015
Fluorescence in situ hybridization (FISH) and/or array-comparative genomic hybridization (aCGH) performed after initial banding cytogenetics is still the gold standard for detection of chromosomal rearrangements. Although aCGH provides a higher resolution, FISH has two main advantages over the array-based approaches: (1) it can be applied to characterize balanced as well ...
Bronet Fernando F IVI Madrid, Madrid, Spain. Electronic address: - - 2014
To study if it is possible to identify embryo sex from embryo cleavage timings. Retrospective and observational study. University-affiliated private fertility center. Women undergoing preimplantion genetic diagnosis. INTERVENTION[S): All biopsied embryos were cultured in an Embryoscope incubator with time-lapse technology. Cleavage timing from insemination to day 3 and all kinetic ...
Fadhlaoui-Zid Karima K 1] Biology Department, Colorado College, Colorado Springs, CO, USA [2] Laboratory of Genetics, Immunology, and Human Pathologies, Faculty of Science of Tunis, University Tunis El Manar, Tunis, - - 2014
The male genetic landscape of the territory currently known as Tunisia is hampered by the scarcity of data, especially from cosmopolitan areas such as the coastal city of Sousse. In order to alleviate this lacuna, 220 males from Sousse were examined, for the first time, for more than 50 Y-chromosome ...
Wei Yanchang - - 2014
During meiotic cell cycle progression, unequal divisions take place resulting in a large oocyte and two diminutive polar bodies. The first polar body contains a subset of bivalent chromosomes, whereas the second polar body contains a haploid set of chromatids. One unique feature of the female gamete is that the ...
Augustinos Antonios A - - 2014
The Bactrocera dorsalis species complex currently harbors approximately 90 different members. The species complex has undergone many revisions in the past decades, and there is still an ongoing debate about the species limits. The availability of a variety of tools and approaches, such as molecular-genomic and cytogenetic analyses, are expected ...
Zepeda-Cisneros Cristina Silvia - - 2014
Anastrepha ludens is among the pests that have a major impact on México's economy because it attacks fruits as citrus and mangoes. The Mexican Federal government uses integrated pest management to control A. ludens through the Programa Nacional Moscas de la Fruta [National Fruit Fly Program, SAGARPA-SENASICA]. One of the ...
De Krom G G Department of Obstetrics & Gynaecology, Maastricht University Medical Centre, Maastricht, The Netherlands School for Oncology and Developmental Biology, GROW, Maastricht University, Maastricht, The Netherlands - - 2014
Do clinical characteristics of recurrent miscarriage couples with a chromosomal abnormality and who opt for PGD differ from couples that decline PGD after extensive genetic counselling? No differences in clinical characteristics are identified between recurrent miscarriage couples carrying a structural chromosomal abnormality who opt for PGD compared with those that ...
Kalachaveedu Mangathayaru M a Department of Pharmacognosy , Sri Ramachandra University , Chennai , Tamil Nadu , - - 2014
Major saponins of Brahmi (Bacopa monniera, Fam: Scrophulariaceae) - bacosides A and B - were isolated from the total methanol extract and characterised based on melting point, TLC, IR, (1)H NMR and (13)C NMR. They were evaluated for their in vitro cytogenetic effects on human peripheral blood lymphocytes by chromosomal ...
Mohamed Amal Mahmoud AM Human Cytogenetics Department, National Research Centre, Cairo, - - 2014
We describe a large family from the Gaza Strip presented with multiple congenital anomalies. The proband was presented with intellectual disability and multiple congenital anomalies including cleft palate, low-set ears, everted upper lip, diaphragmatic hernia, and arthrogryposis. Pedigree analysis showed 19 affected patients over five generations, only 6 were alive ...
Othman Moneeb A K MA Jena University Hospital, Friedrich Schiller University, Institute of Human Genetics, Jena, - - 2014
Cytogenetic classification of acute lymphoblastic leukemia (ALL) is primarily based on numerical and structural chromosomal abnormalities. In T-cell ALL (T-ALL), chromosomal rearrangements are identified in up to 70% of the patients while the remaining patients show a normal karyotype. In the present study, a 16-year-old male was diagnosed with T-precursor ...
Gainsford Ashton A College of Marine and Environmental Sciences, James Cook University, Townsville, QLD, 4811, Australia; ARC Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, QLD, 4811, - - 2014
Hybridization is an important evolutionary process, with ecological and behavioural factors influencing gene exchange between hybrids and parent species. Patterns of hybridization in anemonefishes may result from living in highly specialized habitats and breeding status regulated by size-based hierarchal social groups. Here morphological, ecological and genetic analyses in Kimbe Bay, ...
Bugmyrin Sergey V SV Institute of Biology of Karelian Research Centre, Russian Academy of Sciences (IB KarRC RAS), Petrozavodsk, Russia. Electronic address: - - 2014
The objective of the study was detection of hybrid larvae in Ixodes persulcatus and Ixodes ricinus cohabitation sites. To this end, the following three tasks were solved: interspecies crossing of ticks, evaluation of typical morphological signs of the hybrid larvae, and analysis of collected specimens from sites of sympatry. Under ...
Soileau Bridgette B Department of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, TX, - - 2014
The identification of an underlying chromosome abnormality frequently marks the endpoint of a diagnostic odyssey. However, families are frequently left with more questions than answers as they consider their child's future. In the case of rare chromosome conditions, a lack of longitudinal data often makes it difficult to provide anticipatory ...
Haufler Christopher H CH Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, Kansas 66049 - - 2014
There have been three periods of significant discovery in the exploration of fern and lycophyte genetics. First, during the 1930s, Andersson-Kottö conducted crossing studies on ferns. The publication of Manton's magnum opus on fern chromosomes in 1950 stimulated the second. The third emerged from Klekowski's 1973 American Journal of Botany ...
Sanders A R AR Department of Psychiatry and Behavioral Sciences,NorthShore University HealthSystem Research - - 2014
Findings from family and twin studies support a genetic contribution to the development of sexual orientation in men. However, previous studies have yielded conflicting evidence for linkage to chromosome Xq28. Method We conducted a genome-wide linkage scan on 409 independent pairs of homosexual brothers (908 analyzed individuals in 384 families), ...
Bini Carla C Department of Medical and Surgical Sciences, DIMEC, Institute of Legal Medicine, University of Bologna, Italy. Electronic address: - - 2014
Requests for solving complex kinship casework involving at least one female are increasing and in these circumstances the analysis of X-chromosomal STR markers plays a relevant role. Actually, it is well known the superior statistical power of X-STRs compared to autosomal markers in solving relationship when two sisters or half-sisters ...
Larmuseau Maarten H D MH UZ Leuven, Laboratory of Forensic Genetics and Molecular Archaeology, Leuven, Belgium; KU Leuven, Forensic Biomedical Sciences, Department of Imaging & Pathology, Leuven, Belgium; KU Leuven, Laboratory of Socioecology and Social Evolution, Department of Biology, Leuven, Belgium. Electronic address: - - 2014
Currently, several different Y-chromosomal phylogenies and haplogroup nomenclatures are presented in scientific literature and at conferences demonstrating the present diversity in Y-chromosomal phylogenetic trees and Y-SNP sets used within forensic and anthropological research. This situation can be ascribed to the exponential growth of the number of Y-SNPs discovered due to ...
Ekin Atalay A Department of Perinatology, Izmir Tepecik Training and Research Hospital, Izmir, - - 2014
Abstract Objective: Our aim is to determine the frequency of chromosomal abnormalities and also to identify the role of structural malformations on the chromosomal abnormality risk among fetuses with echogenic bowel. Methods: Over a 6-year period fetuses with echogenic bowel (FEB) were retrospectively evaluated. The pregnancies with intra-amniotic bleeding history, ...
Xie Yingjun Y Department of Prenatal Diagnosis, The First Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. - - 2014
It has been well established that the 5p deletion causes Cri du chat syndrome, typically characterized by a cat‑like cry, and that duplication of 18q causes Edwards syndrome; the two are rare genetic abnormalities that separately lead to physical and mental impairments. However, the severity of the clinicopathological characteristics that ...
Ross Laura L School of Biological Sciences, Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, EH9 3JT, - - 2014
Extraordinarily high rates of recombination have been observed in some eusocial species. The most popular explanation is that increased recombination increases genetic variation among workers, which in turn increases colony performance, for example by increasing parasite resistance. However, support for the generality of higher recombination rates among eusocial organisms remains ...
Lajoie Bryan R BR Program in Systems Biology, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 368 Plantation Street, Worcester, MA 01605-0103, USA. Electronic address: - - 2014
Over the last decade, development and application of a set of molecular genomic approaches based on the chromosome conformation capture method (3C), combined with increasingly powerful imaging approaches, have enabled high resolution and genome-wide analysis of the spatial organization of chromosomes. The aim of this paper is to provide guidelines ...
Cubeñas-Potts Caelin C Department of Biochemistry & Molecular Biology, Johns Hopkins Bloomberg School of Public Health, 21205, Baltimore, MD, USA; Department of Biology, Emory University, Atlanta, GA, - - 2014
Sumoylation is essential for progression through mitosis, but the specific protein targets and functions remain poorly understood. In this study, we used chromosome spreads to more precisely define the localization of SUMO-2/3 to the inner-centromere and protein scaffold of mitotic chromosomes. We also developed methods to immunopurify proteins modified by ...
Xiao Ning N College of Bioscience and Biotechnology and Jiangsu Key Laboratory of Crop Genetics and Physiology, Yangzhou University, Yangzhou, Jiangsu Province, China, - - 2014
Using leaf osmotic potential and plant survival rate as chilling-tolerant trait indices, we identified two major quantitative trait loci qLOP2 and qPSR2 - 1 (39.3-kb region) and Os02g0677300 as the cold-inducible gene for these loci. Chilling stress tolerance (CST) at the seedling stage is an important trait affecting rice production ...
Liau Joy J Maternal-Fetal Care and Genetics, University of California, San Diego, San Diego, CA; Department of Radiology, University of California, San Diego, San Diego, - - 2014
Sonographic aneuploidy markers and structural anomalies associated with the 5 most common chromosomal aneuploidies are organized and simplified to highlight the many sonographic findings that are commonly seen with each aneuploidy. Identification of these findings allows families to have the option to pursue prenatal genetic testing to confirm or exclude ...
Bo Kailiang K Horticulture College, Nanjing Agricultural University, Nanjing, 210095, - - 2014
Comparative genetic mapping revealed the origin of Xishuangbanna cucumber through diversification selection after domestication. QTL mapping provided insights into the genetic basis of traits under diversification selection during crop evolution. The Xishuangbanna cucumber, Cucumis sativus L. var. xishuangbannanesis Qi et Yuan (XIS), is a semi-wild landrace from the tropical southwest ...
Szyfter Krzysztof K Institute of Human Genetics, Polish Academy of Sciences, Poznan, - - 2014
The knowledge of the biology of head and neck squamous cell carcinoma (HNSCC) has had relatively little impact on the improvement in oncologic outcome up to date. However, the identification of oncogenes and tumor suppressor genes (TSGs) involved in cancer progression contributes to the understanding of the molecular pathways involved ...
Capalbo Antonio A 1] GENERA, Centers for Reproductive Medicine, Rome, Naples, Umbertide, Marostica, Italy [2] GENETYX, Molecular Genetics Laboratory, Marostica, Vicenza, - - 2014
Comprehensive chromosome screening (CCS) methods are being extensively used to select chromosomally normal embryos in human assisted reproduction. Some concerns related to the stage of analysis and which aneuploidy screening method to use still remain. In this study, the reliability of blastocyst-stage aneuploidy screening and the diagnostic performance of the ...
Delicado Alicia - - 2014
BackgroundWe and others have previously reported that familial cytogenetic studies in apparently de novo genomic imbalances may reveal complex or uncommon inheritance mechanisms.MethodsA familial, combined genomic and cytogenetic approach was systematically applied to the parents of all patients with unbalanced genome copy number changes.ResultsDiscordant array-CGH and FISH results in the ...
Liu Quanli Q Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China. Electronic address: - - 2014
A new mazF-based strategy for large-scale and scarless genome rearrangements in Saccharomyces cerevisiae was developed. We applied this method to delete designed internal (26.5 kbp) and terminal (28.9 kbp) regions located on the left arm of the chromosome XI of S. cerevisiae BY4741. The number of transformants was increased by ...
Webb Bryn D BD Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1498, New York, NY, 10029, - - 2014
The goal of molecular cytogenetic testing for children presenting with developmental delay (DD) is to identify or exclude genetic abnormalities that are associated with cognitive, behavioral and/or motor symptoms. Until 2010, chromosome analysis was the standard first-line genetic screening test for evaluation of patients with DD when a specific syndrome ...
Rothammer Sophie - - 2014
Since the pig is one of the most important livestock animals worldwide, mapping loci that are associated with economically important traits and/or traits that influence animal welfare is extremely relevant for efficient future pig breeding. Therefore, the purpose of this study was a genome-wide mapping of quantitative trait loci (QTL) ...
Braulke Friederike F University Medicine Gottingen, Germany; - - 2014
International Prognostic Scoring Systems are used to determine the individual risk profile of myelodysplastic syndrome patients. For the assessment of International Prognostic Scoring Systems, an adequate chromosome banding analysis of the bone marrow is essential. Cytogenetic information is not available for a substantial number of patients (5-20%) with dry marrow ...
Maddalo Danilo D Memorial Sloan Kettering Cancer Center, Cancer Biology and Genetics Program, 1275 York Avenue, New York, New York 10065, - - 2014
Chromosomal rearrangements have a central role in the pathogenesis of human cancers and often result in the expression of therapeutically actionable gene fusions. A recently discovered example is a fusion between the genes echinoderm microtubule-associated protein like 4 (EML4) and anaplastic lymphoma kinase (ALK), generated by an inversion on the ...
Warshauer David H DH Institute of Applied Genetics, Department of Molecular and Medical Genetics, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107, - - 2014
STRait Razor (the STR Allele Identification Tool - Razor) was developed as a bioinformatic software tool to detect short tandem repeat (STR) alleles in massively parallel sequencing (MPS) raw data. The method of detection used by STRait Razor allows it to make reliable allele calls for all STR types in ...
Fiorentino Francesco F Molecular Genetics Laboratory, 'GENOMA', Via di Castel Giubileo, 11, 00138 Rome, Italy - - 2014
Can next-generation sequencing (NGS) techniques be used reliably for comprehensive aneuploidy screening of human embryos from patients undergoing IVF treatments, with the purpose of identifying and selecting chromosomally normal embryos for transfer? Extensive application of NGS in clinical preimplantation genetic screening (PGS) cycles demonstrates that this methodology is reliable, allowing ...
Sandhu Nitika N Division of Plant Breeding, Genetics, and Biotechnology, International Rice Research Institute, DAPO Box 7777, Metro Manila, The Philippines Department of Molecular Biology and Biotechnology, CCS Haryana Agricultural University, Hisar-125004, - - 2014
The development of rice varieties for dry direct-seeded conditions can be accelerated by selecting suitable traits. In the present investigation, traits hypothesized to be important for direct-seeded conditions in rainfed systems, including seedling emergence, early vegetative vigour, nutrient uptake, nodal root number, and root hair length and density, were characterized ...
Cormier Fabien F Centre de recherche de Chappes, Biogemma, Route d'Ennezat CS90126, 63720, Chappes, - - 2014
This study identified 333 genomic regions associated to 28 traits related to nitrogen use efficiency in European winter wheat using genome-wide association in a 214-varieties panel experimented in eight environments. Improving nitrogen use efficiency is a key factor to sustainably ensure global production increase. However, while high-throughput screening methods remain ...
Pellestor Franck F Laboratory of Chromosomal Genetics, Department of Medical Genetics, Arnaud de Villeneuve Hospital, Montpellier CHRU, Montpellier, France; INSERM Unit Plasticity of the Genome and Aging, Institute of Functional Genomics, Montpellier, France. Electronic address: - - 2014
To review the discovery of chromothripsis and analyze its impact on human reproduction. Database and literature analysis. University hospital. Carriers of massive and complex chromosomal rearrangements. Cytogenetic analysis and molecular testing (fluorescence in situ hybridization, microarray, whole-genome sequencing). Chromothripsis occurrence in human gametes and preimplantation embryos, with regard to the ...
Fuller Zachary L ZL The Pennsylvania State University; - - 2014
There has been a renewed interest in investigating the role of stabilizing selection acting on genome-wide traits such as codon usage bias. Codon bias, when synonymous codons are utilized at unequal frequencies, occurs in a wide variety of taxa. Standard evolutionary models explain the maintenance of codon bias through a ...
Wang Xindan X Department of Microbiology and Immunobiology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, - - 2014
Bacterial chromosomes are organized in stereotypical patterns that are faithfully and robustly regenerated in daughter cells. Two distinct spatial patterns were described almost a decade ago in our most tractable model organisms. In recent years, analysis of chromosome organization in a larger and more diverse set of bacteria and a ...
Rosser Neil N Department of Genetics, Evolution and Environment, University College London, Gower Street, London, WC, 1E 6BT, - - 2014
Multilocus clines between Müllerian mimetic races of Heliconius butterflies provide a classic example of the maintenance of hybrid zones and their importance in speciation. Concordant hybrid zones in the mimics Heliconius erato and H. melpomene in northern Peru were carefully documented in the 1980s, and this prior work now permits ...
Yakut Sezin S Department of Medical Biology and Genetics, Akdeniz University, School of Medicine, ANTALYA, - - 2014
Objective: The aim of this study was presentation of the ultrasonographic findings and perinatal autopsy of cases with rare chromosomal abnormalities. Material and Method: A total of 10125 prenatal cases over 17 years including 8731 amniocentesis, 973 chorionic villus sampling, and 421 fetal blood sampling cases were evaluated for prenatal ...
Saldarriaga Wilmar W Professor University of Valle. Department of Obstetrics and Gynecology; Department of morphology. University of - - 2014
The aim of this study was to determine the diagnostic accuracy of comparative genomic hybridization (CGH) compared with karyotyping for the detection of numerical and structural chromosomal alterations in prenatal diagnosis. A meta-analysis was performed using searches of PubMed, EMBASE, CENTRAL, Cochrane Register of Diagnostic Test Accuracy Studies, Google Scholar, ...
Boyle Eileen M EM Division of Molecular Pathology, The Institute of Cancer Research, London, UK; Service des maladies du Sang, Hopital Huriez, Centre Hospitalier Regional Universitaire de Lille, Lille, - - 2014
Risk stratification in myeloma requires an accurate assessment of the presence of a range of molecular abnormalities including the differing IGH translocations and the recurrent copy number abnormalities that can impact clinical behavior. Currently, interphase fluorescence in situ hybridization is used to detect these abnormalities. High failure rates, slow turnaround, ...
Maccaferri Marco - - 2014
Durum wheat (Triticum durum Desf.) is a tetraploid grown in the medium to low-precipitation areas of the Mediterranean Basin, North America and South-West Asia. Genomics applications in durum wheat have the potential to boost exploitation of genetic resources and to advance understanding of the genetics of important complex traits (e.g. ...
Tsigenopoulos Costas S CS Institute of Marine Biology, Biotechnology and Aquaculture (IMBBC), Hellenic Centre for Marine Research (HCMR), Thalassocosmos, Ex-US base at Gournes Pediados, 715 00 Heraklion, Crete, Greece. Electronic address: - - 2014
An updated second linkage map was constructed for the gilthead sea bream, Sparus aurata L., a fish species of great economic importance for the Mediterranean aquaculture industry. In contrast to the first linkage map which mainly consisted of genomic microsatellites (SSRs), the new linkage map is highly enriched with SSRs ...
Brand Harrison H Psychiatric and Neurodevelopmental Genetics Unit, Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, - - 2014
Structural variation (SV) is a significant component of the genetic etiology of both neurodevelopmental and psychiatric disorders; however, routine guidelines for clinical genetic screening have been established only in the former category. Genome-wide chromosomal microarray (CMA) can detect genomic imbalances such as copy-number variants (CNVs), but balanced chromosomal abnormalities (BCAs) ...
Meng Nana N Department of Ophthalmology, Affiliated People's Hospital, Jiangsu University , Zhenjiang , China - - 2014
Abstract Aims: A meta-analysis was conducted to evaluate the association of rs1533428, rs12994401, rs10202118 polymorphism on chromosome 2p16.3 with POAG susceptibility. Methods: Systematic searches were performed on the electronic databases, the Cochrane Central Register of Controlled Trials, PubMed, ISI Web of Knowledge (Version 4.5), Chinese national knowledge infrastructure (CNKI), and ...
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