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Martin-Fernandez Laura L Departamento de Fisica Aplicada, Universidad de Granada, Avda. Fuentenueva s/n, 18071 Granada, Spain. - - 2014
Functional response estimation and population tracking in predator-prey systems are critical problems in ecology. In this paper we consider a stochastic predator-prey system with a Lotka-Volterra functional response and propose a particle filtering method for: (a) estimating the behavioral parameter representing the rate of effective search per predator in the ...
Arnan Xavier X CREAF, Cerdanyola del Vallès, 08193, Catalunya, Spain; Faculty of Biology, TU Darmstadt, Schnittspahnstrasse 3, D-64287, Darmstadt, - - 2014
Understanding species distributions and diversity gradients is a central challenge in ecology and requires prior knowledge of the functional traits mediating species' survival under particular environmental conditions. While the functional ecology of plants has been reasonably well explored, much less is known about that of animals. Ants are among the ...
Yu Feng - - 2014
We have optimized two double-hybrid density functionals (DHDFs) within the frameworks of B2PLYP and mPW2-PLYP against the S22B database. These two functionals are denoted as B2NC-PLYP and mPW2NC-PLYP, where "NC" represents non-covalent interaction. The DHDFs of B2NC-PLYP and mPW2NC-PLYP are optimized free of dispersion and counterpoise corrections with triple-ζ quality ...
Rathour Rahul Kumar RK Cellular Neurophysiology Laboratory, Molecular Biophysics Unit, Indian Institute of Science, Bangalore, Karnataka 560012, - - 2014
The maintenance of ion channel homeostasis, or channelostasis, is a complex puzzle in neurons with extensive dendritic arborization, encompassing a combinatorial diversity of proteins that encode these channels and their auxiliary subunits, their localization profiles, and associated signaling machinery. Despite this, neurons exhibit amazingly stereotypic, topographically continuous maps of several ...
Duecker Felix F Maastricht - - 2014
TMS allows noninvasive manipulation of brain activity in healthy participants and patients. The effectiveness of TMS experiments critically depends on precise TMS coil positioning, which is best for most brain areas when a frameless stereotactic system is used to target activation foci based on individual fMRI data. From a purely ...
Schwabe Tobias T Center for Bioinformatics and Institute of Physical Chemistry, University of Hamburg, Bundesstraße 43, 20146 Hamburg, Germany. - - 2014
Some representative density functionals are assessed for isomerization reactions in which heteroatoms are systematically substituted with heavier members of the same element group. By this, it is investigated if the functional performance depends on the elements involved, i.e. on the external potential imposed by the atomic nuclei. Special emphasis is ...
Crescenzo Antonio Di - - 2014
We investigate an extension of the spike train stochastic model based on the conditional intensity, in which the recovery function includes an interaction between several excitatory neural units. Such function is proposed as depending both on the time elapsed since the last spike and on the last spiking unit. Our ...
Beresford Thomas P TP University of - - 2014
The psychological adaptive mechanism (PAM) model for systematic clinical assessment can be applied in any human setting in which individuals adapt to the conditions of their lives. This report focuses on applying the PAM assessment technique to the stress and anxiety of physical illness. To do so, we must consider ...
Faridi A A Center of Excellence in the Animal Sciences Department, Ferdowsi University of Mashhad, Mashhad, Iran, - - 2014
In this study, 2 alternative growth functions, the Lomolino and the extreme value function (EVF), are introduced and their ability to predict body, carcass, and breast weight in ducks evaluated. A comparative study was carried out of these equations with standard growth functions: Gompertz, exponential, Richards, and generalized Michaelis-Menten. Goodness ...
Watanabe Takanori T Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI, USA. Electronic address: - - 2014
Substantial evidence indicates that major psychiatric disorders are associated with distributed neural dysconnectivity, leading to strong interest in using neuroimaging methods to accurately predict disorder status. In this work, we are specifically interested in a multivariate approach that uses features derived from whole-brain resting state functional connectomes. However, functional connectomes ...
Rudzinski Joseph F - - 2014
Low resolution coarse-grained (CG) models enable highly efficient simulations of complex systems. The interactions in CG models are often iteratively refined over multiple simulations until they reproduce the one-dimensional (1-D) distribution functions, e.g., radial distribution functions (rdfs), of an all-atom (AA) model. In contrast, the multiscale coarse-graining (MS-CG) method employs ...
Salem Farzaneh F Centre for Applied Pharmaceutical Research, Manchester Pharmacy School, The University of Manchester, Stopford Building, Oxford Road, Manchester, M13 9PT, - - 2014
Current cytochrome P450 (CYP) 1A2 and 3A4 ontogeny profiles, which are derived mainly from in vitro studies and incorporated in paediatric physiologically based pharmacokinetic models, have been reported to under-predict the in vivo clearances of some model substrates in neonates and infants. We report ontogeny functions for these enzymes as ...
Ugarte Maria D MD Department of Statistics and Operations Research, Universidad Pública de Navarra, Navarra, - - 2014
This is a discussion of the paper "Overview of object oriented data analysis" by J. Steve Marron and Andrés M. Alonso.
Spitz Jérôme J Littoral Environnement & Sociétés, UMR 7266 Université de La Rochelle/CNRS, 17042, La Rochelle, France; Marine Mammal Research Unit, Fisheries Centre, University of British Columbia, 2202 Main Mall, Vancouver, British Columbia, V6T 1Z4, - - 2014
1. Understanding "Why a prey is a prey for a given predator?" can be facilitated through trait-based approaches that identify linkages between prey and predator morphological and ecological characteristics and highlight key functions involved in prey selection. 2. Enhanced understanding of the functional relationships between predators and their prey is ...
Hasegawa Daniel K DK Department of Biological Sciences, Clemson University, Clemson, SC, USA 29634; Current Address: USDA-ARS, U.S. Vegetable Laboratory, 2700 Savannah Highway, Charleston, SC, USA - - 2014
The past decade has seen significant advances in the field of innexin biology, particularly in the model invertebrate organisms, the nematode Caenorhabditis elegans and the fly Drosophila melanogaster. However, advances in genomics and functional techniques during this same period are ushering in a period of comparative innexin biology. Insects are ...
Leander Jacob J Fraunhofer-Chalmers Centre, Chalmers Science Park, SE-412 88 Gothenburg, Sweden; Mathematical Sciences, Chalmers University of Technology and University of Gothenburg, Gothenburg, Sweden. Electronic address: - - 2014
In this paper we consider the problem of estimating parameters in ordinary differential equations given discrete time experimental data. The impact of going from an ordinary to a stochastic differential equation setting is investigated as a tool to overcome the problem of local minima in the objective function. Using two ...
Arribas-Gil Ana A Departamento de Estadística, Universidad Carlos III de Madrid, Getafe 28903, - - 2014
We propose a new method to visualize and detect shape outliers in samples of curves. In functional data analysis, we observe curves defined over a given real interval and shape outliers may be defined as those curves that exhibit a different shape from the rest of the sample. Whereas magnitude ...
Eckl Katja-Martina KM Dermatogenetics, Div. of Human Genetics and Dept. of Dermatology and Venereology, Innsbruck Medical University, Innsbruck, Austria; Dermatogenetics, Cologne Center for Genomics, University of Cologne, Cologne, - - 2014
The aim of the present study was to assess a recently established 3D model of congenital ichthyosis, representing severe epidermal barrier function defects, for skin penetration and permeation. We have generated disease models by knockdown of either TGM1 or ALOXE3 in primary human keratinocytes and using keratinocytes and fibroblasts from ...
Chen Bing-Yu BY Department of Environmental and Occupational Medicine, National Taiwan University (NTU) College of Medicine and NTU Hospital, Taipei, - - 2014
In our previous longitudinal study, we found that exposure to current levels of ambient total fungal spores was related to a reduction of childhood lung function. However, the biological properties of various taxa of fungal spores varied greatly, as well as their health effects. In this study, we aimed to ...
Wu Ruobing R The University of Hong Kong, Hong - - 2014
Line drawings and digital arts appear everywhere, from simple icons and logos to cartoons, maps, and illustrations. We define art patterns as the subset of line drawings and digital arts that are comprised of repeated elements. There exist textures that share characteristics with art patterns. Examples of such textures include ...
Zan Peng P School of Mechatronics Engineering and Automation of Shanghai University, Shanghai Key Laboratory of Power Station Automation Technology, Shanghai - PR - - 2014
In this paper, a novel artificial anal sphincter (AAS) system based on rebuilding the rectal sensation function is proposed to treat human fecal incontinence. The executive mechanism of the traditional AAS system was redesigned and integrated for a simpler structure and better durability. The novel executive mechanism uses a sandwich ...
van der Pol Marjon M Health Economics Research Unit, University of Aberdeen, Abedeen, UK. Electronic address: - - 2014
The specification of the utility function has received limited attention within the discrete choice experiment (DCE) literature. This lack of investigation is surprising given that evidence from the contingent valuation literature suggests that welfare estimates are sensitive to different specifications of the utility function. This study investigates the effect of ...
He Kevin K Department of Biostatistics, University of Michigan, 1420 Washington Hts., Ann Arbor, MI , 48109-2029, USA, - - 2014
The survival function is often of chief interest in epidemiologic studies of time to an event. We develop methods for evaluating center-specific survival outcomes through a ratio of survival functions. The proposed method assumes a center-stratified additive hazards model, which provides a convenient framework for our purposes. Under the proposed ...
Filgueiras Ernesto E Communication and Arts Department, Beira Interior University, Covilhã, - - 2014
Successful cases of professional reintegration were achieved when adequate conditions were created for the adaptation of the worker with disability to the working environment and to the professional activity, allowing them to carry out all their functions without any restriction. In this sense, this paper presents a methodology for professional ...
Wang Jiasheng J State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, China. - - 2014
Silica-based nanocomposites with amorphous silica as the matrix or carrier along with a functional component have been extensively investigated. These nanocomposites combine the advantages of both silica and the functional components, demonstrating great potential for various applications. To synthesize such composites, one of the most frequently used methods is reverse ...
Samonds Jason M JM Center for the Neural Basis of Cognition and Computer Science Department, Carnegie Mellon University, Pittsburgh, PA 15213, U.S.A. - - 2014
We propose using the statistical measurement of the sample skewness of the distribution of mean firing rates of a tuning curve to quantify sharpness of tuning. For some features, like binocular disparity, tuning curves are best described by relatively complex and sometimes diverse functions, making it difficult to quantify sharpness ...
Wallace Andrew James - - 2014
Static correlation energies (Estat) are calculated in a range of basis sets for a chem- ically diverse collection of atoms and molecules. The reliability of a basis set in capturing Estat is assessed according to: mean and maximum absolute deviations from near-exact Estat estimates, monotonic convergence to the complete basis ...
Baranzelli M C MC Laboratorio de Ecología Evolutiva - Biología Floral, Instituto Multidisciplinario de Biología Vegetal (IMBIV), CONICET-Universidad Nacional de Córdoba, Córdoba, - - 2014
Pollinator-mediated natural selection on single traits, such as corolla tube or spur length, has been well documented. However, flower phenotypes are usually complex, and selection is expected to act on several traits that functionally interact rather than on a single isolated trait. Despite the fact that selection on complex phenotypes ...
Bolam S G SG Centre for Environment, Fisheries and Aquaculture Science, Pakefield Road, Lowestoft, Suffolk NR33 0HT, UK. Electronic address: - - 2014
There is a growing need to understand the functional implications of anthropogenic pressures, such as those following coastal disposal of dredged material. Current assessments, based on taxonomic structure of benthic organisms, only provide a limited capacity to determine functional impacts or recovery. This study assesses recovery of two intertidal dredged ...
Ramm Steven A SA Evolutionary Biology, Bielefeld University, Morgenbreede 45, 33615, Bielefeld, - - 2014
Larger testes are considered the quintessential adaptation to sperm competition. However, the strong focus on testis size in evolutionary research risks ignoring other potentially adaptive features of testicular function, many of which will also be shaped by post-mating sexual selection. Here we advocate a more integrated research programme that simultaneously ...
Wang Jingdong J Microsoft Research Aisa, - - 2014
We address the problem of approximate nearest neighbor (ANN) search for visual descriptor indexing. Most spatial partition trees, such as KD trees, VP trees, and so on, follow the hierarchical binary space partitioning framework. The key effort is to design different partition functions (hyperplane or hypersphere) to divide the points ...
Thorson James T - - 2014
State-space estimation methods are increasingly used in ecology to estimate productivity and abundance of natural populations while accounting for variability in both population dynamics and measurement processes. However, functional forms for population dynamics and density dependence often will not match the true biological process, and this may degrade the performance ...
Kinney Justin B JB Simmons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, U.S.A. - - 2014
Motivated by data-rich experiments in transcriptional regulation and sensory neuroscience, we consider the following general problem in statistical inference: when exposed to a high-dimensional signal S, a system of interest computes a representation R of that signal, which is then observed through a noisy measurement M. From a large number ...
Liao Tianjun T State Key Laboratory of Complex System Simulation, Beijing Institute of System Engineering, Beijing, China. - - 2014
Abstract The benchmark functions and some of the algorithms proposed for the special session on real parameter optimization of the 2005 IEEE Congress on Evolutionary Computation (CEC'05) have played and still play an important role in the assessment of the state of the art in continuous optimization. In this note, ...
Yu Hao H Jiangsu Key Laboratory of Urban ITS Southeast University, Si Pai Lou #2, Nanjing 210096, China; Jiangsu Province Collaborative Innovation Center of Modern Urban Traffic Technologies, Si Pai Lou #2, Nanjing 210096, China. Electronic address: - - 2014
Spatial analysis technique has been introduced as an innovative approach for hazardous road segments identification (HRSI). In this study, the performance of two spatial analysis methods and four conventional methods for HRSI was compared against three quantitative evaluation criteria. The spatial analysis methods considered in this study include the local ...
Thuiller Wilfried W Laboratoire d'Ecologie Alpine, UMR CNRS 5553, Université Joseph Fourier, BP 53, FR-38041 Grenoble Cedex 9, - - 2014
Despite the recognized joint impact of climate and land cover change on facets of biodiversity and their associated functions, risk assessments have primarily evaluated impacts on species ranges and richness. Here we quantify the sensitivity of the functional structure of European avian assemblages to changes in both regional climate and ...
Adamson M W MW Department of Mathematics, University of Leicester, University Road, Leicester , LE1 7RH, UK, - - 2014
When we construct mathematical models to represent biological systems, there is always uncertainty with regards to the model specification-whether with respect to the parameters or to the formulation of model functions. Sometimes choosing two different functions with close shapes in a model can result in substantially different model predictions: a ...
Vázquez-Castellanos Jorge F - - 2014
The main limitations in the analysis of viral metagenomes are perhaps the high genetic variability and the lack of information in extant databases. To address these issues, several bioinformatic tools have been specifically designed or adapted for metagenomics by improving read assembly and creating more sensitive methods for homology detection. ...
Lin Cunjie C Academy of Mathematics and Systems Science, Chinese Academy of Sciences, No. 55 Zhongguancun East Road, Haidian District, Beijing , 100190, China, - - 2014
Quantile residual lifetime function is a more comprehensive quantitative measure for residual lifetimes than the mean residual lifetime function. It also incorporates the median residual life function, which is less restrictive than the model based on the mean residual lifetime. In this study, we propose a semiparametric estimator of the ...
Mardirossian Narbe N Department of Chemistry, University of California, Berkeley, and Chemical Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. - - 2014
A 10-parameter, range-separated hybrid (RSH), generalized gradient approximation (GGA) density functional with nonlocal correlation (VV10) is presented. Instead of truncating the B97-type power series inhomogeneity correction factors (ICF) for the exchange, same-spin correlation, and opposite-spin correlation functionals uniformly, all 16 383 combinations of the linear parameters up to fourth order (m ...
Agrawal Shikha S Department of Computer Science and Engineering, University Institute of Technology, Rajiv Gandhi Proudyogiki Vishwavidhyalaya, Bhopal, MP, India. Electronic address: - - 2014
The determination of the most stable conformers of a molecule can be formulated as a global optimization problem. Knowing the stable conformers of a molecule is important because it allows us to understand its properties and behavior based on its structure. The most stable conformation is that involving the global ...
Boens Noël N Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200f - bus 02404, 3001 Leuven, Belgium. - - 2014
The deterministic identifiability analysis of photophysical models for the kinetics of excited-state processes, assuming errorless time-resolved fluorescence data, can verify whether the model parameters can be determined unambiguously. In this work, we have investigated the identifiability of several uncommon models for time-resolved fluorescence with underlying distributions of rate constants which ...
Suwa Makiko - - 2014
The automatic classification of GPCRs by bioinformatics methodology can provide functional information for new GPCRs in the whole 'GPCR proteome' and this information is important for the development of novel drugs. Since GPCR proteome is classified hierarchically, general ways for GPCR function prediction are based on hierarchical classification. Various computational ...
Liu Ming-Yu - - 2014
We propose a new objective function for clustering. This objective function consists of two components: the entropy rate of a random walk on a graph and a balancing term. The entropy rate favors formation of compact and homogeneous clusters, while the balancing function encourages clusters with similar sizes and penalizes ...
Liu Yashu - - 2014
Complex diseases such as major depression affect people over time in complicated patterns. Longitudinal data analysis is thus crucial for understanding and prognosis of such diseases and has received considerable attention in the biomedical research community. Traditional classification and regression methods have been commonly applied in a simple (controlled) clinical ...
Ide Jaime S - - 2014
Much effort has been made to better understand the complex integration of distinct parts of the human brain using functional magnetic resonance imaging (fMRI). Altered functional connectivity between brain regions is associated with many neurological and mental illnesses, such as Alzheimer and Parkinson diseases, addiction, and depression. In computational science, ...
Kong Shengchun S Department of Biostatistics, University of Michigan, 1415 Washington Heights, Ann Arbor, MI - - 2014
We consider finite sample properties of the regularized high-dimensional Cox regression via lasso. Existing literature focuses on linear models or generalized linear models with Lipschitz loss functions, where the empirical risk functions are the summations of independent and identically distributed (iid) losses. The summands in the negative log partial likelihood ...
Sroysang Banyat B Department of Mathematics and Statistics, Faculty of Science and Technology, Thammasat University, Pathum Thani 12121, - - 2014
Some new Hermite-Hadamard type inequalities for differentiable convex functions were presented by Xi and Qi. In this paper, we present new generalizations on the Xi-Qi inequalities.
Overgaard Morten M CNRU, CFIN, MindLab, Aarhus University, , Noerrebrogade 44, Building 10G, DK-8000 Aarhus, - - 2014
This article proposes a new model to interpret seemingly conflicting evidence concerning the correlation of consciousness and neural processes. Based on an analysis of research of blindsight and subliminal perception, the reorganization of elementary functions and consciousness framework suggests that mental representations consist of functions at several different levels of ...
Fiore Vincenzo G VG Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London London, - - 2014
The effects of striatal dopamine (DA) on behavior have been widely investigated over the past decades, with "phasic" burst firings considered as the key expression of a reward prediction error responsible for reinforcement learning. Less well studied is "tonic" DA, where putative functions include the idea that it is a ...
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