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Lara M M Department of Biology, Faculty of Marine and Environmental Sciences, University of Cádiz, Av. República Saharaui s/n, 11510 Puerto Real, Spain. Electronic address: - - 2014
Tidal cycles at benthic habitats induce a set of periodic environmental changes in variables like salinity, temperature and sediment water content which are able to stress benthic organisms. Consequently, a natural selection temporally correlated with tides affects the fitness of genotypes (wi) depending on their adaptation degree. Classic population genetics ...
Simón Luis L Laboratory of Parasitology, Faculty of Pharmacy & IBSAL, University of Salamanca, Salamanca, - - 2014
Zoonotic filarioses caused by Dirofilaria immitis and Dirofilaria repens are transmitted by culicid mosquitoes. Therefore Dirofilaria transmission depends on climatic factors like temperature and humidity. In spite of the dry climate of most of the Spanish territory, there are extensive irrigated crops areas providing moist habitats favourable for mosquito breeding. ...
Jore Solveig - - 2014
Global environmental change is causing spatial and temporal shifts in the distribution of species and the associated diseases of humans, domesticated animals and wildlife. In the on-going debate on the influence of climate change on vectors and vector-borne diseases, there is a lack of a comprehensive interdisciplinary multi-factorial approach utilizing ...
Bassu Simona S Unité d'Agronomie, INRA-AgroParisTech, BP 01, 78850, Thiverval-Grignon, - - 2014
Potential consequences of climate change on crop production can be studied using mechanistic crop simulation models. While a broad variety of maize simulation models exist, it is not known whether different models diverge on grain yield responses to changes in climatic factors, or whether they agree in their general trends ...
Wakefield J J 1] Department of Statistics, University of Washington, Seattle, WA, USA [2] Department of Biostatistics, University of Washington, Seattle, WA, - - 2014
In a common pharmacogenomic scenario, outcome measures are compared for treated and untreated subjects across genotype-defined subgroups. The key question is whether treatment benefit (or harm) is particularly strong in certain subgroups, and therefore the statistical analysis focuses on the interaction between treatment and genotype. However, genome-wide analysis in such ...
Simon Cory M CM Department of Chemical and Biomolecular Engineering, University of California, Berkeley, California, USA. - - 2014
In this work, we address the question of which thermodynamic factors determine the deliverable capacity of methane in nanoporous materials. The deliverable capacity is one of the key factors that determines the performance of a material for methane storage in automotive fuel tanks. To obtain insights into how the molecular ...
Malina Magdalena - - 2014
Abstract To locate multiple interacting quantitative trait loci (QTL) influencing a trait of interest within experimental populations, usually methods as the Cockerham's model are applied. Within this framework, interactions are understood as the part of the joined effect of several genes which cannot be explained as the sum of their ...
Sarojinie Fernando W T P WT Institute of Fundamental Sciences, Massey University, New - - 2014
The spatial relative risk function is defined as the ratio of densities describing respectively the spatial distribution of cases and controls. It has proven to be an effective tool for visualizing spatial variation in risk in many epidemiological applications over the past 20years. We discuss the generalization of this function ...
Shi Xingjie X Department of Biostatistics, School of Public Health, Yale University, New Haven, Connecticut, United States of America; School of Statistics and Management, Shanghai University of Finance and Economics, Shanghai, - - 2014
In cancer studies with high-throughput genetic and genomic measurements, integrative analysis provides a way to effectively pool and analyze heterogeneous raw data from multiple independent studies and outperforms "classic" meta-analysis and single-dataset analysis. When marker selection is of interest, the genetic basis of multiple datasets can be described using the ...
Mujic Alija Bajro AB Botany and Plant Pathology, Oregon State University, Corvallis, Oregon, 97331-2902, United States of - - 2014
Rhizopogon subgenus Villosuli are the only members of the genus known to form an ectomycorrhizal relationship exclusively with Pseudotsuga. The specificity of this host relationship is unusual as Rhizopogon is broadly associated with several tree genera within the Pinaceae and relationships with a host genus are typically distributed across Rhizopogon ...
Guan Xiying X School of Aerospace and Mechanical Engineering and Bioengineering Center, University of Oklahoma, Norman, - - 2014
Recently we reported that middle ear pressure (MEP), middle ear effusion (MEE), and ossicular changes each contribute to the loss of tympanic membrane (TM) mobility in a guinea pig model of acute otitis media (AOM) induced by S. pneumoniae (Guan and Gan, 2013). However, it is not clear how those ...
Vedantham Ram - - 2014
A new source-type identification method, Reduction and Species Clustering Using Episodes (ReSCUE), was developed to exploit the temporal synchronicity typically observed between ambient species in high time resolution fine particulate matter (PM2.5) data to form clusters that vary together. High time-resolution (30 min) PM2.5 sampling was conducted for a month ...
Fernández-Durán Juan José - - 2014
Abstract Fernández-Durán, J. J. (2004): "Circular distributions based on nonnegative trigonometric sums," Biometrics, 60, 499-503, developed a family of univariate circular distributions based on nonnegative trigonometric sums. In this work, we extend this family of distributions to the multivariate case by using multiple nonnegative trigonometric sums to model the joint ...
Horta Marco Aurelio MA a Oswaldo Cruz Foundation, National School of Public Health , Rio de Janeiro , - - 2014
To determine the time-lag effect of meteorological factors on the relative risk (RR) of dengue incidence in Coronel Fabriciano city, Brazil, we applied a distributed lag nonlinear model, a modeling framework that can simultaneously represent nonlinear exposure-response dependencies and delayed effects, to establish the association between dengue incidence and weather ...
Al-Quwaidhi Abdulkareem J AJ Newcastle University, United Kingdom; Ministry of Health, Saudi Arabia. Electronic address: - - 2014
To compare the estimates and projections of type 2 diabetes mellitus (T2DM) prevalence in Saudi Arabia from a validated Markov model against other modelling estimates, such as those produced by the International Diabetes Federation (IDF) Diabetes Atlas and the Global Burden of Disease (GBD) project. A discrete-state Markov model was ...
Da Yang Y Department of Animal Science, University of Minnesota, Saint Paul, Minnesota, United States of - - 2014
We established a genomic model of quantitative trait with genomic additive and dominance relationships that parallels the traditional quantitative genetics model, which partitions a genotypic value as breeding value plus dominance deviation and calculates additive and dominance relationships using pedigree information. Based on this genomic model, two sets of computationally ...
de Andrade Luciano L Department of Nursing, State University of the West of Parana, Foz do Iguaçu, Parana, Brazil ; Department of Surgery, Duke University Health System, Durham, North Carolina, United States of America ; Duke Global Health Institute, Duke University, Durham, North Carolina, United States of - - 2014
Road traffic injuries (RTI) are a major public health epidemic killing thousands of people daily. Low and middle-income countries, such as Brazil, have the highest annual rates of road traffic fatalities. In order to improve road safety, this study mapped road traffic fatalities on a Brazilian highway to determine the ...
Condori Bruno B Liaison Office in Bolivia, International Potato Center, La Paz, La Paz, - - 2014
Austral summer frosts in the Andean highlands are ubiquitous throughout the crop cycle, causing yield losses. In spite of the existing warming trend, climate change models forecast high variability, including freezing temperatures. As the potato center of origin, the region has a rich biodiversity which includes a set of frost ...
Kaminski Michal F MF Department of Gastroenterological Oncology, The Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, , Warsaw, - - 2014
This study aimed to develop and validate a model to estimate the likelihood of detecting advanced colorectal neoplasia in Caucasian patients. We performed a cross-sectional analysis of database records for 40-year-old to 66-year-old patients who entered a national primary colonoscopy-based screening programme for colorectal cancer in 73 centres in Poland ...
Välitalo P P School of Pharmacy, University of Eastern Finland, Kuopio, - - 2014
Population pharmacometric modeling is used to explain both population trends as well as the sources and magnitude of variability in pharmacokinetic and pharmacodynamics data; the later, in part, by taking into account patient characteristics such as weight, age, renal function and genetics. The approach is best known for its ability ...
Jochems Eline C - - 2014
Self-determination theory is potentially useful for understanding reasons why individuals with mental illness do or do not engage in psychiatric treatment. The current study examined the psychometric properties of three questionnaires based on self-determination theory-The Treatment Entry Questionnaire (TEQ), Health Care Climate Questionnaire (HCCQ), and the Short Motivation Feedback List ...
Cornuet Jean-Marie JM Inra, UMR1062 Cbgp, Montpellier, France, Université Montpellier 2, UMR CNRS 5149, I3M, Montpellier, France. Institut de Biologie Computationnelle (IBC), 95 rue de la Galéra, 34095 Montpellier, France, CNRS-UM2, Institut de Biologie Computationnelle, LIRMM, Montpellier, - - 2014
DIYABC is a software package for a comprehensive analysis of population history using approximate Bayesian computation (ABC) on DNA polymorphism data. Version 2.0 implements a number of new features and analytical methods. It allows: (i) the analysis of single nucleotide polymorphism (SNP) data at large number of loci, apart from ...
Hadfield Jarrod D JD Institute of Evolutionary Biology, University of Edinburgh, United - - 2014
Abstract The evolution of traits involved in ecological interactions such as predator-prey, host-parasite, and plant-pollinator interactions, are likely to be shaped by the phylogenetic history of both parties. We develop generalized linear mixed-effects models (GLMM) that estimate the effect of both parties' phylogenetic history on trait evolution, both in isolation ...
Divekar Rohit - - 2014
There has been an increased interest in studying other factors that affect asthma pathogenesis and cause heterogeneity in prevalence and incidence of asthma. The reason there are such varied expression patterns of disease in asthmatics is because of multiple variables that affect the pathogenesis of asthma. As an exemplar of ...
Sawaya Michael R - - 2014
Diffraction anisotropy is characterized by variation in diffraction quality with reciprocal lattice direction. In the example presented here, diffraction extended to 2.1 Å resolution along a* and c* directions but only to 3.0 Å along the b* direction. Severe anisotropy such as this is often associated with lack of detail ...
Zararsiz Gökmen - - 2014
MicroRNA profiling is an important task to investigate miRNA functions and recent technologies such as microarray, single nucleotide polymorphism (SNP), quantitative real-time PCR (qPCR), and next-generation sequencing (NGS) have played a major role for miRNA analysis. In this chapter, we give an overview on statistical approaches for gene expressions, SNP, ...
Choi Saerona - - 2014
Objectives: The major purpose of this study was to identify risk factors affecting truck crashes on freeways and propose recommendations for safer truck traffic operations. Methods: Truck crashes were analyzed to identify how truck traffic safety is related to prevailing traffic and weather conditions. Prevailing traffic conditions were characterized by ...
Kaminsky David A - - 2014
The purpose of this review is to discuss the present systems biology approach to asthma and how it is helping to define asthma subtypes. Although the general concept of systems biology will be discussed, the article will focus on recent developments in the field related to asthma. The most recent ...
Stamovlasis Dimitrios - - 2014
The present study examines the dimensions of oughts under a nonlinear perspective. Ought-approach and ought-avoidance have been proposed as two different dimensions of oughts, which have an opposite effect on subjects' arousal level under achievement situation. The change in arousal level measured by heart rates per minute (HRPM) was modeled ...
Chang Li-Yen LY a National Chiayi University , Department of Marketing and Logistics/Transportation , Chia-Yi , - - 2014
Objective: A manhole cover is a removable plate forming the lid over the opening of a manhole to allow traffic to pass over the manhole and to prevent people from falling in. Because most manhole covers are placed in roadway traffic lanes, if these manhole covers are not appropriately installed ...
Schmidt Robert L RL From the Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, - - 2014
Context.-Study comparisons rest on the assessment of applicability or external validity. Population characteristics are an important component of external validity and, although there has been a heightened awareness of deficiencies in reporting in diagnostic test accuracy (DTA) studies, the reporting of populations in DTA studies has not been investigated. Objective.-To ...
Khosravi Yahya Y Department of Occupational Health, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, - - 2014
There can be little doubt that the construction is the most hazardous industry in the worldwide. This study was designed to modeling the factors affecting unsafe behavior from the perspective of safety supervisors. The qualitative research was conducted to extract a conceptual model. A structural model was then developed based ...
Mellin C C Australian Institute of Marine Science, , PMB No. 3, Townsville MC, Townsville, Queensland 4810, Australia, The Environment Institute and School of Earth and Environmental Sciences, The University of Adelaide, , South Australia 5005, Australia, South Australian Research and Development Institute, , PO Box 120, Henley Beach, South Australia 5022, - - 2014
The 'diversity-stability hypothesis', in which higher species diversity within biological communities buffers the risk of ecological collapse, is now generally accepted. However, empirical evidence for a relationship between β-diversity (spatial turnover in community structure) and temporal stability in community structure remains equivocal, despite important implications for theoretical ecology and conservation ...
Fedigan Linda M LM Department of Anthropology, University of Calgary, Alberta, - - 2014
The leading explanatory model for the widespread occurrence of color vision polymorphism in Neotropical primates is the heterozygote superiority hypothesis, which postulates that trichromatic individuals have a fitness advantage over other phenotypes because redgreen chromatic discrimination is useful for foraging, social signaling, or predator detection. Alternative explanatory models predict that ...
Feher Kristen K Max-Planck Institute of Molecular Plant Physiology, Potsdam-Golm, Germany ; Institute for Biochemistry and Biology, University of Potsdam, Potsdam, - - 2014
Heterosis, the greater vigor of hybrids compared to their parents, has been exploited in maize breeding for more than 100 years to produce ever better performing elite hybrids of increased yield. Despite extensive research, the underlying mechanisms shaping the extent of heterosis are not well understood, rendering the process of ...
Bai Yuntao Y Division of Environmental Health Sciences, College of Public Health, The Ohio State University, Columbus, Ohio, United States of - - 2014
In this study, we aim to identify key climatic factors that are associated with the transmission of Japanese encephalitis virus in areas located near the Three Gorges Dam, between 1997 and 2008. We identified three geographical regions of Chongqing, based on their distance from the Three Gorges Dam. Collectively, the ...
Scott Caitlin C Department of Psychology, Arizona State University, Tempe, - - 2014
ABSTRACT. Objective: Previous research has identified several aspects of behavioral undercontrol that are associated with heavy drinking and problems. Further, research on the acquired preparedness model (Smith and Anderson, 2001) has identified biased learning as a potential mechanism of these effects. Traits like sensation seeking have been linked to stronger ...
Saito Kodai K Department of Mathematical Informatics, The University of Tokyo, Tokyo, - - 2014
In the Twitter blogosphere, the number of followers is probably the most basic and succinct quantity for measuring popularity of users. However, the number of followers can be manipulated in various ways; we can even buy follows. Therefore, alternative popularity measures for Twitter users on the basis of, for example, ...
Gayevskiy Velimir V School of Biological Sciences, University of Auckland, Auckland, New - - 2014
Bayesian inference methods are extensively used to detect the presence of population structure given genetic data. The primary output of software implementing these methods are ancestry profiles of sampled individuals. While these profiles robustly partition the data into subgroups, currently there is no objective method to determine whether the fixed ...
Finucane Mariel M MM The J. David Gladstone Institutes, San Francisco, California, United States of - - 2014
Obesity is an important and intractable public health problem. In addition to the well-known risk factors of behavior, diet, and genetics, gut microbial communities were recently identified as another possible source of risk and a potential therapeutic target. However, human and animal-model studies have yielded conflicting results about the precise ...
Bansal Vikas V Department of Cardiovascular Genetics, Experimental and Clinical Research Center, Charité - Universitätsmedizin Berlin and Max Delbrück Center (MDC) for Molecular Medicine, Berlin, Germany ; Department of Mathematics and Computer Science, Free University of Berlin, Berlin, - - 2014
Copy number variations (CNVs) are one of the main sources of variability in the human genome. Many CNVs are associated with various diseases including cardiovascular disease. In addition to hybridization-based methods, next-generation sequencing (NGS) technologies are increasingly used for CNV discovery. However, respective computational methods applicable to NGS data are ...
Chan Matthew H T MH School of Mathematics and Statistics, University of Sydney, Sydney, New South Wales, - - 2014
There have been numerous empirical studies on the fitness consequences of behavioural syndromes in various animal taxa; however, the ecological and evolutionary implications on a population level are still poorly understood. To better understand these implications, we develop a non-linear age-structured mathematical model to qualitatively examine the evolutionary consequences of ...
Tang Fenyang F Jiangsu Province Center for Disease Control and Prevention, Nanjing, Jiangsu, - - 2014
This study aimed to describe the spatial and temporal trends of Shigella incidence rates in Jiangsu Province, People's Republic of China. It also intended to explore complex risk modes facilitating Shigella transmission. County-level incidence rates were obtained for analysis using geographic information system (GIS) tools. Trend surface and incidence maps ...
Valverde-Albacete Francisco J FJ Departamento de Lenguajes y Sistemas Informáticos, Universidad Nacional de Educación a Distancia, Madrid, - - 2014
THE MOST WIDELY SPREAD MEASURE OF PERFORMANCE, ACCURACY, SUFFERS FROM A PARADOX: predictive models with a given level of accuracy may have greater predictive power than models with higher accuracy. Despite optimizing classification error rate, high accuracy models may fail to capture crucial information transfer in the classification task. We ...
Nguyen Thuan T Department of Public Health and Preventive Medicine, Oregon Health and Science University, Portland, OR 97239, - - 2014
Model search strategies play an important role in finding simultaneous susceptibility genes that are associated with a trait. More particularly, model selection via the information criteria, such as the BIC with modifications, have received considerable attention in quantitative trait loci (QTL) mapping. However, such modifications often depend upon several factors, ...
Farzadfar Farshad F Non-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran, Endocrinology and Metabolism Research center, Endocrinology and Metabolism Research Institute, Tehran, Iran. - - 2014
Iran has witnessed a substantial demographic and health transition, especially during the past 2 decades, which necessitates updated evidence-based policies at national and indeed at subnational scale. The National and Subnational Burden of Diseases, Injuries, and Risk Factors (NASBOD) Study aims to provide the required evidence based on updated data ...
Kasaeian Amir A Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran, Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medecine, Tehran, Iran. mohamadk@tums.ac.ir, - - 2014
Statistical modeling and developing new methods for estimating burden of diseases, injuries and risk factors is a fundamental concern in studying the country health situation for better health management and policy making. Bayesian autoregressive multilevel model is a strong method for this kind of study though in complex situations it ...
Parsaeian Mahboubeh M Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran, Non-Communicable Disease Research Center, Endocrinology and Metabolism Population Science Research Institute, Tehran University of Medical Sciences, Tehran, Iran. mohamadk@ tums.ac.ir, - - 2014
Identifying the burden of disease and its inequality between geographical regions is an important issue to study health priorities. Estimating burden of diseases using statistical models is inevitable especially in the context of rare data availability. To this purpose, the spatio-temporal model can provide a statistically sound approach for explaining ...
Eastwood John G JG South Western Sydney Local Health District, Locked Mail Bag 7279, Liverpool BC 1871, Sydney, NSW Australia ; School of Public Health and Community Medicine, The University of New South Wales, Sydney, NSW 2052 Australia ; School of Women's and Children's Health, The University of New South Wales, Sydney, NSW 2052 Australia ; School of Public Health, University of Sydney, Sydney, NSW 2006 Australia ; School of Public Health, Griffith University, Gold Coast, QLD 4222 - - 2014
A recent criticism of social epidemiological studies, and multi-level studies in particular has been a paucity of theory. We will present here the protocol for a study that aims to build a theory of the social epidemiology of maternal depression. We use a critical realist approach which is trans-disciplinary, encompassing ...
Weitkamp Katharina K Department of Child and Adolescent Psychiatry, Psychotherapy, and Psychosomatics, University Medical Centre Hamburg-Eppendorf, Hamburg, - - 2014
During the past several years, there has been a growing interest in the negative effects that providing therapy may have on therapists. Of special interest is a phenomenon called secondary traumatization, which can arise while working with traumatized clients. To develop a simple screening tool for secondary traumatization, a quantitative ...
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