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Chen Shyi-Ming - - 2014
In this paper, we present a new method for fuzzy forecasting based on two-factors second-order fuzzy-trend logical relationship groups and the probabilities of trends of fuzzy-trend logical relationships. Firstly, the proposed method fuzzifies the historical training data of the main factor and the secondary factor into fuzzy sets, respectively, to ...
Chaturvedi Nimisha - - 2014
A number of statistical models has been proposed for studying the association between geneexpression and copy number data in integrated analysis. The next step is to compare associationpatterns between different groups of samples. We propose a method, named dSIM, to find differences in association between copy number and geneexpression, when ...
Pissis Solon P - - 2014
Identifying repeated factors that occur in a string of letters or common factors that occur in a setof strings represents an important task in computer science and biology. Such patterns are calledmotifs, and the process of identifying them is called motif extraction. In biology, motif extractionconstitutes a fundamental step in ...
Vilseck Jonah Z JZ Department of Chemistry, Yale University , New Haven, Connecticut 06520-8107, United - - 2014
The recently developed Charge Model 5 (CM5) is tested for its utility in condensed-phase simulations. The CM5 approach, which derives partial atomic charges from Hirshfeld population analyses, provides excellent results for gas-phase dipole moments and is applicable to all elements of the periodic table. Herein, the adequacy of scaled CM5 ...
McCullough Erin L EL Division of Biological Sciences, University of Montana, Missoula, MT, USA - - 2014
The horns of giant rhinoceros beetles are a classic example of the elaborate morphologies that can result from sexual selection. Theory predicts that sexual traits will evolve to be increasingly exaggerated until survival costs balance the reproductive benefits of further trait elaboration. In Trypoxylus dichotomus, long horns confer a competitive ...
Leontyev Igor V IV Department of Chemistry, University of California Davis, One Shields Avenue, Davis, California 95616, - - 2014
Earlier, using phenomenological approach, we showed that in some cases polarizable models of condensed phase systems can be reduced to nonpolarizable equivalent models with scaled charges. Examples of such systems include ionic liquids, TIPnP-type models of water, protein force fields, and others, where interactions and dynamics of inherently polarizable species ...
Olatunji Bunmi O BO Vanderbilt University, Nashville, TN, USA - - 2014
The current research evaluated a bifactor model for the Disgust Emotion Scale (DES) in three samples: N = 1,318 nonclinical participants, N = 152 clinic-referred patients, and N = 352 nonclinical participants. The primary goals were to (a) use bifactor modeling to examine the latent structure of the DES and ...
Gerrard Paul P Spaulding Rehabilitation Hospital and Harvard Medical School, Boston, - - 2014
To investigate the neurobehavioral pattern of recovery of consciousness as reflected by performance on the subscales of the Coma Recovery Scale - Revised (CRS-R). Retrospective item response theory and factor analysis. Inpatient rehabilitation facilities in the United States and Europe. Rehabilitation inpatients (N=180) with post-traumatic disturbance in consciousness who participated ...
Bandyopadhyay Uttam U Department of Statistics, University of Calcutta, Kolkata, West Bengal, 700035, - - 2014
Matched case-control paired data are commonly used to study the association between a disease and an exposure of interest. This work provides a consistent test for this association with respect to the conditional odds ratio (ORc), which is a measure of association that is also valid in prospective studies. We ...
Cabras Stefano S Department of Statistics, Universidad Carlos III de Madrid, Getafe, Spain; Department of Mathematics and Informatics, Università di Cagliari, Cagliari, - - 2014
This paper considers the problem of selecting a set of regressors when the response variable is distributed according to a specified parametric model and observations are censored. Under a Bayesian perspective, the most widely used tools are Bayes factors (BFs), which are undefined when improper priors are used. In order ...
Dixon Josie J Personal Social Services Research Unit, London School of Economics, London, - - 2014
This paper examines the numbers of people with dementia who could be diagnosed and the likely cost-effectiveness of a one-off screen for dementia for people aged 75 years in England and Wales. The study uses static decision modelling to compare a one-off screen for dementia with a no-screen scenario. Estimates for ...
Sesé-Abad Albert A Balearic Islands University, Palma, - - 2014
Evidence-based practice may be implemented more successfully if the barriers to its implementation have been previously identified. Many of the available instruments to measure these barriers have been validated in single samples or without confirmatory analyses. The objective of the study was to contrast the goodness of fit of two ...
Wang Kai K Department of Industrial and Management System Engineering, West Virginia University , Morgantown, West Virginia 26506, United - - 2014
One of the most fundamental steps in risk assessment is to quantify the exposure-response relationship for the material/chemical of interest. This work develops a new statistical method, referred to as SKQ (stochastic kriging with qualitative factors), to synergistically model exposure-response data, which often arise from multiple sources (e.g., laboratories, animal ...
Cayuela Hugo H Laboratoire d'Ecologie des Hydrosystèmes Naturels et Anthropisés, Université Lyon I, CNRS, UMR 5023, 69622, Villeurbanne, France, - - 2014
Iteroparity is an adaptive response to uncertainty in reproductive success. However, spreading reproductive success over multiple reproduction events during a lifetime is constrained by adult mortality and the stochasticity associated with interactions between external factors and physiological states. The acquisition of information about environmental conditions during the growth of progeny ...
Mitchell R J RJ a Transport and Road Safety (TARS) Research , University of New South Wales , Sydney , - - 2014
Various human factors classification frameworks have been used to identified causal factors for clinical adverse events. A systematic review was conducted to identify human factors classification frameworks that identified the causal factors (including human error) of adverse events in a hospital setting. Six electronic databases were searched, identifying 1997 articles ...
Fessler Daniel M T DM Department of Anthropology and Center for Behavior, Evolution, and Culture, University of California, 341 Haines Hall, Los Angeles, CA, 90095-1553, USA, - - 2014
Across taxa, strength and size are elementary determinants of relative fighting capacity; in species with complex behavioral repertoires, numerous additional factors also contribute. When many factors must be considered simultaneously, decision-making in agonistic contexts can be facilitated through the use of a summary representation. Size and strength may constitute the ...
Rowsey Ross R School of Molecular Biosciences and Center for Reproductive Biology, Washington State University, Pullman, WA 99164, - - 2014
The most important risk factor for human aneuploidy is increasing maternal age, but the basis of this association remains unknown. Indeed, one of the earliest models of the maternal-age effect-the "production-line model" proposed by Henderson and Edwards in 1968-remains one of the most-cited explanations. The model has two key components: ...
Béchaux Camille C ANSES, French Agency for Food, Environmental and Occupational Health Safety, 27-31 Avenue du Général Leclerc, 94701 Maisons-Alfort, France. Electronic address: - - 2014
As cadmium accumulates mainly in kidney, urinary concentrations are considered as relevant data to assess the risk related to cadmium. The French Nutrition and Health Survey (ENNS) recorded the concentration of cadmium in the urine of the French population. However, as with all biomonitoring data, it needs to be linked ...
Béchaux Camille - - 2014
Abstract New data are available in the field of risk assessment: the biomonitoring data which is measurement of the chemical dose in a human tissue (e.g. blood or urine). These data are original because they represent direct measurements of the dose of chemical substances really taken up from the environment, ...
Lemons P R PR U.S. Fish and Wildlife Service, Marine Mammals Management, 1011 East Tudor Road, Anchorage, AK, 99503, - - 2014
Genotypes are frequently used to assess alternative reproductive strategies such as extra-pair paternity and conspecific brood parasitism in wild populations. However, such analyses are vulnerable to genotyping error or molecular artefacts that can bias results. For example, when using multilocus microsatellite data, a mismatch at a single locus, suggesting the ...
Zanoli Raffaele R Dipartimento di Scienze Agrarie, Alimentari e Ambientali (D3A), Università Politecnica delle Marche, Ancona, - - 2014
Certification is an essential feature in organic farming, and it is based on inspections to verify compliance with respect to European Council Regulation-EC Reg. No 834/2007. A risk-based approach to noncompliance that alerts the control bodies to activate planning inspections would contribute to a more efficient and cost-effective certification system. ...
Wahl Simone - - 2014
With the help of epigenome-wide association studies (EWAS), increasing knowledge on the role of epigenetic mechanisms such as DNA methylation in disease processes is obtained. In addition, EWAS aid the understanding of behavioral and environmental effects on DNA methylation. In terms of statistical analysis, specific challenges arise from the characteristics ...
Darlay Rebecca R School of Biology, Miall Building, University of Leeds, Leeds LS2 9JT, UK. Electronic address: - - 2014
Foetal death, or abortion at term, in sheep is of major significance to the livestock industry, accounting for more than £24million lost per annum. We have investigated whether there is a genetic component to abortion within two flocks of pedigree Charollais sheep, one followed from 1989 to 2006, the other ...
Tsuruta S S Animal and Dairy Science Department, University of Georgia, Athens 30602. Electronic address: - - 2014
Assigning unknown parent groups (UPG) in mixed-model equations using single-step genomic BLUP was investigated to reduce bias and to increase accuracy in genomic estimated breeding values (GEBV). The original UPG were defined based on the animal's birth year and the sex of the animal's unknown parents. Combining the last 2 ...
Abrams Steven S Interuniversity Institute for Biostatistics and statistical Bioinformatics, Hasselt University, Agoralaan 1 Gebouw D, B3590 Diepenbeek, Belgium - - 2014
In recent years, it has been shown that individual heterogeneity in the acquisition of infectious diseases has a large impact on the estimation of important epidemiological parameters such as the (basic) reproduction number. Therefore, frailty modeling has become increasingly popular in infectious disease epidemiology. However, so far, using frailty models, ...
Gao H H Institute of Animal Sciences, Chinese Academy of Agricultural Science, Beijing, People's Republic of - - 2014
Given the drawbacks of implementing multivariate analysis for mapping multiple traits in genome-wide association study (GWAS), principal component analysis (PCA) has been widely used to generate independent 'super traits' from the original multivariate phenotypic traits for the univariate analysis. However, parameter estimates in this framework may not be the same ...
Kumar Paulraj Ranjith PR Department of Electronics and Communication, PSR Engineering College, Sivakasi, - - 2014
Coronary artery disease due to atherosclerosis is an epidemic in India. An estimated 1.3 million Indians died from this in 2000. The projected death from coronary artery disease by 2016 is 2.98 million.OBJECTIVE: To build an effective model which assorts the individuals, whether they belong to the normal group, risk ...
Stefanile Cristina C Department of Health Sciences, Section of Psychology, University of Florence, Via di San Salvi, 12, Pad. 26, 50135 Florence, Italy. Electronic address: - - 2014
The current study examined the validity of the Italian version of the Acceptance of Cosmetic Surgery Scale (ACSS; Henderson-King & Henderson-King, 2005) in a sample of 378 Italian adult women. A series of confirmatory factor analyses were conducted. A three-factor solution provided the best fit to the data and confirmed ...
Xu Yihuan Y ImClone LLC, A Wholly Owned Subsidiary of Eli Lilly and Company, 440 Route 22, Bridgewater, NJ - - 2014
The g - and - h distributional family is generated from a relatively simple transformation of the standard normal and can approximate a broad spectrum of distributions. Consequently, it is easy to use in simulation studies and has been applied in multiple areas, including risk management, stock return analysis and ...
Rajon Etienne E Laboratoire de Biométrie et Biologie Évolutive, Unité Mixte de Recherche (UMR) CNRS 5558, Université de Lyon, Université Lyon 1, F-69622 Villeurbanne, - - 2014
Abstract Genotypes that hedge their bets can be favored by selection in an unpredictably varying environment. Bet hedging can be achieved by systematically expressing several phenotypes, such as one that readily attempts to reproduce and one that procrastinates in a dormant stage. But how much of each phenotype should a ...
Gorski Mathias M Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany; Department of Nephrology, University Hospital Regensburg, Regensburg, - - 2014
Genome-wide association studies are usually accompanied by imputation techniques to complement genome-wide SNP chip genotypes. Current imputation approaches separate the phasing of study data from imputing, which makes the phasing independent from the reference data. The two-step approach allows for updating the imputation for a new reference panel without repeating ...
Fruean Sn S Department of Agriculture, GPO Box 858, Canberra, Australia Capital Territory, 2601, - - 2014
To assess Australia's targeted surveillance to detect an incursion of screw-worm fly (Chrysomya bezziana). A multi-criteria analysis shell was used to combine data on potential pathways of entry, availability of host species and environmental factors affecting survival of screw-worm fly in order to map spatial variation in the relative likelihood ...
Walters Raymond K RK Department of Psychology,University of Notre Dame,Notre - - 2014
Epistasis is a growing area of research in genome-wide studies, but the differences between alternative definitions of epistasis remain a source of confusion for many researchers. One problem is that models for epistasis are presented in a number of formats, some of which have difficult-to-interpret parameters. In addition, the relation ...
Gutierrez Benjamin B US Food and Drug Administration, Silver Spring, Maryland - - 2014
Variance estimates for detector energy resolution metrics can be used as stopping criteria in Monte Carlo simulations for the purpose of ensuring a small uncertainty of those metrics and for the design of variance reduction techniques. The authors derive an estimate for the variance of two energy resolution metrics, the ...
Gadermann Anne M AM Centre for Health Evaluation and Outcome Sciences, St. Paul's Hospital, University of British Columbia, 620B-1081 Burrard Street, Vancouver, BC V6Z - - 2014
To derive job condition scales for future studies of the effects of job conditions on soldier health and job functioning across Army Military Occupation Specialties (MOSs) and Areas of Concentration (AOCs) using Department of Labor (DoL) Occupational Information Network (O*NET) ratings. A consolidated administrative dataset was created for the "Army ...
Pasaniuc Bogdan B Department of Pathology and Laboratory Medicine, Geffen School of Medicine, University of California Los Angeles, Bioinformatics Interdepartmental Program, University of California Los Angeles, Department of Medicine, Lung Biology Center, University of California San Francisco, Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Departments of Epidemiology and Biostatistics, Harvard School of Public Health, Broad Institute of Harvard and MIT, Cambridge, MA, USA. Harvard Medical School, MA, USA. Division of Population Health Sciences and Education, St George's, University of London, UK. Department of Pathology and Laboratory Medicine, Geffen School of Medicine, University of California Los Angeles, Bioinformatics Interdepartmental Program, University of California Los Angeles, Department of Medicine, Lung Biology Center, University of California San Francisco, Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Departments of Epidemiology and Biostatistics, Harvard School of Public Health, Broad Institute of Harvard and MIT, Cambridge, MA, USA. Harvard Medical School, MA, USA. Division of Population Health Sciences and Education, St George's, University of London, UK. bpasaniuc@mednet.ucla.edu - - 2014
Imputation using external reference panels (e.g. 1000 Genomes) is a widely used approach for increasing power in GWAS and meta-analysis. Existing HMM-based imputation approaches require individual-level genotypes. Here, we develop a new method for Gaussian imputation from summary association statistics, a type of data that is becoming widely available. Results: ...
Kaivanto Kim - - 2014
Certain classes of system-level risk depend partly on decentralized lay decision making. For instance, an organization's network security risk depends partly on its employees' responses to phishing attacks. On a larger scale, the risk within a financial system depends partly on households' responses to mortgage sales pitches. Behavioral economics shows ...
Gu Junfei J Centre for Crop Systems Analysis, Department of Plant Sciences, Wageningen University, PO Box 430, 6700 AK Wageningen, The - - 2014
Genetic markers can be used in combination with ecophysiological crop models to predict the performance of genotypes. Crop models can estimate the contribution of individual markers to crop performance in given environments. The objectives of this study were to explore the use of crop models to design markers and virtual ...
Fletcher Paul P University College - - 2014
ABSTRACT Perusing early issues of this Journal from nearly forty years ago, we find many topics on the contents lists that could appear in a current issue. But the resources available to contributors for addressing questions of interest have changed dramatically, not least in the public availability of data. Here ...
Restif Christophe C Center for Computational Biomedicine Imaging and Modeling, Rutgers, The State University of New Jersey, Piscataway, New Jersey, United States of - - 2014
In the effort to define genes and specific neuronal circuits that control behavior and plasticity, the capacity for high-precision automated analysis of behavior is essential. We report on comprehensive computer vision software for analysis of swimming locomotion of C. elegans, a simple animal model initially developed to facilitate elaboration of ...
Katzourakis Aris A Department of Zoology, University of Oxford, Oxford, United - - 2014
Retroviruses have been infecting mammals for at least 100 million years, leaving descendants in host genomes known as endogenous retroviruses (ERVs). The abundance of ERVs is partly determined by their mode of replication, but it has also been suggested that host life history traits could enhance or suppress their activity. ...
Eu-Ahsunthornwattana Jakris J Institute of Genetic Medicine, Newcastle University, International Centre for Life, Newcastle upon Tyne, United Kingdom; Division of Medical Genetics, Department of Internal Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Ratchathevi, Bangkok, - - 2014
Approaches based on linear mixed models (LMMs) have recently gained popularity for modelling population substructure and relatedness in genome-wide association studies. In the last few years, a bewildering variety of different LMM methods/software packages have been developed, but it is not always clear how (or indeed whether) any newly-proposed method ...
Daniulaityte Raminta R a Associate Professor and Associate Director, Center for Interventions, Treatment, and Addictions Research, Boonshoft School of Medicine , Wright State University , Dayton , - - 2014
Abstract The study uses qualitative and quantitative data to describe sources of pain pills for illicit use among young adult (18- to 23-year-old) users. Respondent-driven sampling was used to recruit 383 individuals in the Columbus, Ohio, area. The sample was almost 50% Caucasian and about 55% male. Qualitative interview participants ...
Kruglanski Arie W AW Department of Psychology, University of - - 2014
The construct of motivational readiness is introduced and explored. Motivational readiness is the willingness or inclination, whether or not ultimately realized, to act in the service of a desire. Building on prior relevant conceptions that include, among others, animal learning models (Hull, 1943; Spence, 1956; Tolman, 1955) and personality approaches ...
Chen Youhua Y Department of Renewable Resources, University of Alberta, Edmonton, T6G 2H1, Canada. Electronic address: - - 2014
In this report, we quantitatively analyzed the essential ecological factors that were strongly correlated with the global outbreak of highly pathogenic H5N1 avian influenza. The ecological niche modeling (ENM) was used to reveal the potential outbreak hotspots of H5N1. A two-step modeling procedure has been proposed: we first used BioClim ...
Loveman G A M - - 2014
Actions to enhance survival in a distressed submarine (DISSUB) scenario may be guided in part by knowledge of the likely risk of decompression sickness (DCS) should the crew attempt tower escape. A mathematical model for DCS risk estimation has been calibrated against DCS outcome data from 3,738 exposures of either ...
Leaper Rebecca - - 2014
Understanding the way in which species are associated in communities is a fundamental question in ecology. Yet there remains a tension between communities as highly structured units or as coincidental collections of individualistic species. We explored these ideas using a new statistical approach that clusters species based on their environmental ...
Sepúlveda Nuno N London School of Hygiene and Tropical Medicine, London, UK; Centre of Statistics and Applications of University of Lisbon, Lisbon, - - 2014
Multiple imputation based on chained equations (MICE) is an alternative missing genotype method that can use genetic and nongenetic auxiliary data to inform the imputation process. Previously, MICE was successfully tested on strongly linked genetic data. We have now tested it on data of the HBA2 gene which, by the ...
Pleskac Timothy J - - 2014
In life, risk is reward and vice versa. Unfortunately, the big rewards people desire are relatively unlikely to occur. This relationship between risk and reward or probabilities and payoffs seems obvious to the financial community and to laypeople alike. Yet theories of decision making have largely ignored it. We conducted ...
Yong Hua-Hie - - 2014
Objective: To test and develop, using structural equation modeling, a robust model of the mediational pathways through which health warning labels exert their influence on smokers' subsequent quitting behavior. Method: Data come from the International Tobacco Control Four-Country Survey, a longitudinal cohort study conducted in Australia, Canada, the United Kingdom, ...
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