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Wang Zhiyong Z 1 Toyota Technological Institute at Chicago , Chicago, - - 2014
Abstract Sparse modeling, a feature selection method widely used in the machine-learning community, has been recently applied to identify associations in genetic studies including expression quantitative trait locus (eQTL) mapping. These genetic studies usually involve high dimensional data where the number of features is much larger than the number of ...
Sun Y Y Animal Breeding and Genomics Centre, Wageningen University, PO Box 338, 6700 AH Wageningen, the - - 2014
Because of a ban on the use of beak trimming in some European countries, feather pecking is becoming a substantial problem in the layer industry, both from animal welfare and economic points of view. The feather condition score (FCS) as a measure of feather damage has been shown to be ...
Wu Joseph T JT Department of Community Medicine and School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of - - 2014
Seroprevalence survey is the most practical method for accurately estimating infection attack rate (IAR) in an epidemic such as influenza. These studies typically entail selecting an arbitrary titer threshold for seropositivity (e.g. microneutralization [MN] 1∶40) and assuming the probability of seropositivity given infection (infection-seropositivity probability, ISP) is 100% or similar ...
Bohlmeijer Ernst T ET a Department of Psychology, Health & Technology , University of Twente , Enschede , The - - 2014
Objectives: As people grow older, identity development in later life becomes a more and more relevant topic. Studying processes that hinder or promote identity development in later life is of importance. Within this broader field, there has been a growing interest in narrative foreclosure. Our goal was to develop a ...
Aykanat Tutku - - 2014
Pedigree reconstruction using genetic analysis provides a useful means to estimate fundamental population biology parameters relating to population demography, trait heritability and individual fitness when combined with other sources of data. However, there remain limitations to pedigree reconstruction in wild populations, particularly in systems where parent-offspring relationships cannot be directly ...
Devarajan Karthik K Department of Biostatistics and Bioinformatics, Fox Chase Cancer Center, Philadelphia, PA 19111, U.S.A. - - 2014
Nonnegative matrix factorization (NMF) by the multiplicative updates algorithm is a powerful machine learning method for decomposing a high-dimensional nonnegative matrix V into two nonnegative matrices, W and H, where V~WH. It has been successfully applied in the analysis and interpretation of large-scale data arising in neuroscience, computational biology, and ...
Karacaören Burak B Department of Animal Science, Akdeniz University, Antalya 07059, - - 2014
Most of the associated single nucleotide polymorphisms (SNPs) for genome wide association studies (GWAS) explain very little proportion of phenotypic variance in outbred populations. One reason is; large number of markers raises the problem of multiple hypothesis testing correction using conservative statistical tests in single marker models. Admixture mapping could ...
Floody Owen R OR Department of Psychology and Program in Neuroscience, Bucknell University, Lewisburg, Pennsylvania 17837. Electronic address: - - 2014
Studies using factor analysis have helped describe the organization of copulatory behavior in male rodents. However, the focus of these studies on a few traditional measures may have limited their results. To test this possibility, 74 sexually-experienced male hamsters were observed as they copulated with stimulus females. The measures collected ...
Degiorgio Michael - - 2014
As it becomes increasingly possible to obtain DNA sequences of orthologous genes from diverse setsof taxa, species trees are frequently being inferred from multilocus data. However, the behavior ofmany methods for performing this inference has remained largely unexplored. Some methods have been proven to be consistent given certain evolutionary models, ...
Sobas Frédéric F aHaemostasis Laboratory, Edouard Herriot Hospital, Lyon, France bDepartment of Statistics, Athens University of Economics and Business, Athens, Greece cCryopep, Montpellier, France *Frédéric Sobas and Panagiotis Tsiamyrtzis contributed equally to the writing of the - - 2014
An ideal medical biology internal quality control (IQC) plan should both monitor the laboratory methods efficiently and implement the relevant clinical-biological specifications. However, many laboratories continue to use the 12s quality control rule without considering the high risk of false rejection and without considering the relationship of analytical performance to ...
Arab Ali - - 2014
Malaria is a leading cause of mortality worldwide. There is currently conflicting data and interpretation on how variability in climate factors affects the incidence of malaria. This study presents a hierarchical Bayesian modelling framework for the analysis of malaria versus climate factors in West Africa. The hierarchical Bayesian framework takes ...
Booth Tom T University of Edinburgh, Edinburgh, - - 2014
The current article compares the use of exploratory structural equation modeling (ESEM) as an alternative to confirmatory factor analytic (CFA) models in personality research. We compare model fit, factor distinctiveness, and criterion associations of factors derived from ESEM and CFA models. In Sample 1 (n = 336) participants completed the ...
Navarro Y Y Servicio Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain; Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain; Centro de Vigilancia Sanitaria Veterinaria (VISAVET), Universidad Complutense, Madrid, Spain; CEI Campus Moncloa, UCM-UPM, Madrid, Spain; CIBER Enfermedades Respiratorias, CIBERES, - - 2014
Spoligotyping is the most widely used method for genotyping Mycobacterium bovis (M. bovis). However, its discriminatory power varies widely between countries. MIRU-VNTR typing could be a promising alternative, although it generally requires the time consuming and laborious simplex PCR assays using standard agarose gel electrophoresis. The accuracy of this approach depends ...
Cheon Kyeongmi K Biometrics Research, Merck, West Point, PA 19486, - - 2014
Markov models used to analyze transition patterns in discrete longitudinal data are based on the limiting assumption that individuals follow the common underlying transition process. However, when one is interested in diseases with different disease or severity subtypes, explicitly modeling subpopulation-specific transition patterns may be appropriate. We propose a model ...
Sadyś Magdalena M National Pollen and Aerobiology Research Unit, University of Worcester, Henwick Grove, WR2 6AJ, Worcester, England, UK, - - 2014
An aerobiological survey was conducted through five consecutive years (2006-2010) at Worcester (England). The concentration of 20 allergenic fungal spore types was measured using a 7-day volumetric spore trap. The relationship between investigated fungal spore genera and selected meteorological parameters (maximum, minimum, mean and dew point temperatures, rainfall, relative humidity, ...
Van der Borght Koen - - 2014
Different high-dimensional regression methodologies exist for the selection of variables to predict a continuous variable. To improve the variable selection in case clustered observations are present in the training data, an extension towards mixed-effects modeling (MM) is requested, but may not always be straightforward to implement.In this article, we developed ...
Rehder Bob B Department of Psychology, New York University, New York, NY 10003, United States. Electronic address: - - 2014
Causal graphical models (CGMs) are a popular formalism used to model human causal reasoning and learning. The key property of CGMs is the causal Markov condition, which stipulates patterns of independence and dependence among causally related variables. Five experiments found that while adult's causal inferences exhibited aspects of veridical causal ...
Devon Hjelm R R Department of Computer Science, University of New Mexico, Albuquerque, NM 87131, USA; Mind Research Network, Albuquerque, NM 87106, - - 2014
Matrix factorization models are the current dominant approach for resolving meaningful data-driven features in neuroimaging data. Among them, independent component analysis (ICA) is arguably the most widely used for identifying functional networks, and its success has led to a number of versatile extensions to group and multimodal data. However there ...
Hagemo Jostein S - - 2014
Exsanguination due to trauma-induced coagulopathy is a continuing challenge in emergency trauma care. Fibrinogen is a crucial factor for haemostatic competence, and may be the factor that reaches critically low levels first. Early fibrinogen substitution is advocated by a number of authors. Little evidence exists regarding the indications for fibrinogen ...
Wong Quincy J J QJ Macquarie University, Sydney, New South Wales, - - 2014
A body of research has demonstrated that individuals with Asian ethnicity endorse higher levels of fear of negative evaluation compared with individuals with European ethnicity. To date, no study has examined whether this Asian-European difference may be confounded by the differential interpretation of the measures of fear of negative evaluation ...
Käfer Jos J Université de Lyon; Université Lyon 1 ; CNRS; UMR 5558; Laboratoire de Biométrie et Biologie Evolutive; F-69622, Villeurbanne, - - 2014
Comparing species richness in sister clades that differ in a character state is one of the ways to study factors influencing diversification. While most of its applications have focussed on traits that increase diversification, some have been used to study the association of a trait with lower species richness, e.g. ...
Kolodziejczyk Julia K - - 2014
Abstract Purpose . There is a need for a self-report measure that assesses use of recommended strategies related to weight management. Design . Cross-sectional analysis. Setting . Universities, community. Subjects . Exploratory factor analysis (EFA) involved data from 404 overweight/obese young adults (mean age = 22 years, 48% non-Hispanic white, ...
Sha Qiuying Q Department of Mathematical Sciences, Michigan Technological University, Houghton, MI, - - 2014
With the development of sequencing techniques, there is increasing interest to detect associations between rare variants and complex traits. Quite a few statistical methods to detect associations between rare variants and complex traits have been developed for unrelated individuals. Statistical methods for detecting rare variant associations under family-based designs have ...
Fernández Rosa R Museum of Comparative Zoology & Department of Organismic and Evolutionary Biology, Harvard University, 26 Oxford Street, Cambridge, MA 02138, - - 2014
Relationships between the five extant orders of centipedes have been considered solved based on morphology. Phylogenies based on samples of up to a few dozen genes have largely been congruent with the morphological tree apart from an alternative placement of one order, the relictual Craterostigmomorpha, consisting of two species in ...
Pertoldi Cino C Department of Biotechnology, Chemistry and Environmental Engineering, Section of Biology and Environmental Science, Aalborg University, Sohngårdsholmsvej 57, 9000, Aalborg, Denmark, - - 2014
Theoretical ecologists have long sought to understand how the persistence of populations depends on the interactions between exogenous (biotic and abiotic) and endogenous (e.g., demographic and genetic) drivers of population dynamics. Recent work focuses on the autocorrelation structure of environmental perturbations and its effects on the persistence of populations. Accurate ...
Achia Thomas No - - 2014
Female genital mutilation/cutting (FGM/C) is still prevalent in several communities in Kenya and other areas in Africa, as well as being practiced by some migrants from African countries living in other parts of the world. This study aimed at detecting clustering of FGM/C in Kenya, and identifying those areas within ...
Fang Hang H Department of Orthopaedics, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Road, Guangzhou, 510630, People's Republic of - - 2014
Osteoarthritis (OA) is a prevalent musculoskeletal disease that results in pain and low quality of life for patients, as well as enormous medical and socioeconomic burdens. The molecular mechanisms responsible for the initiation and progression of OA are still poorly understood. As such, mouse models of the disease are having ...
Richter Anne A Department of Psychology, Stockholm University, 106 91, Stockholm, - - 2014
The three constructs of work-family conflict, emotional exhaustion and performance-based self-esteem are all related to tremendous negative consequences for the individual, the organization as well as for society. Even though there are studies that connect two of those constructs, the prospective relations between all three of them have not been ...
Christensen Ole F - - 2014
For a two-breed crossbreeding system, Wei and van der Werf presented a model for genetic evaluation using information from both purebred and crossbred animals. The model provides breeding values for both purebred and crossbred performances. Genomic evaluation incorporates marker genotypes into a genetic evaluation system. Among popular methods are the ...
Nishimura Kunihiro K Department of Preventive Medicine, National Cerebral and Cardiovascular - - 2014
Aim: The Framingham risk score (FRS) is one of the standard tools used to predict the incidence of coronary heart disease (CHD). No previous study has investigated its efficacy for a Japanese population cohort. The purpose of this study was to develop new coronary prediction algorithms for the Japanese population ...
Blair Christopher - - 2014
Debate continues as to whether allopatric speciation or peripatric speciation through a founder effect is the predominant force driving evolution in vertebrates. The mouse lemurs of Madagascar are a system in which evolution has generated a large number of species over a relatively recent time frame. Here, we examine speciation ...
Recknagel Hans H Lehrstuhl für Zoologie und Evolutionsbiologie, Department of Biology, University of Konstanz, 78457, Konstanz, Germany; Institute of Biodiversity, Animal Health & Comparative Medicine, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, - - 2014
Adaptive radiations provide an excellent opportunity for studying the correlates and causes for the origin of biodiversity. In these radiations, species diversity may be influenced by, either, the ecological and physical environment, intrinsic lineage effects, or both. Disentangling the relative contributions of these factors in generating biodiversity remains a major ...
Yap Stevie C Y - - 2014
In this article, we evaluate the factor structure of the Multigroup Ethnic Identity Measure (MEIM; Phinney, 1992) and test whether the MEIM exhibits measurement invariance across ethnic groups taken from a diverse sample of students from 30 different colleges and universities across the United States (N = 9,625). Initial analyses ...
Bright Jo-Anne JA ESR Ltd, Private Bag 92021, Auckland 1142, New Zealand; Department of Statistics, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. Electronic address: - - 2014
We have investigated the suitability of models used to predict expected stutter ratios and their variance developed for autosomal STR markers for application to Y STR markers. Models for expected back stutter, double back stutter, and forward stutter ratios for all loci in the PowerPlex(®) Y multiplex and the heights ...
Almeida Filho J E JE Laboratório de Engenharia Agrícola, Centro de Ciências e Tecnologias Agropecuárias, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, RJ, Brasil - - 2014
We analyzed productivity data obtained from experiments on grain sorghum conducted in 7 locations of its cultivation in Brazil. A total of 25 hybrids were analyzed, of which 22 were pre-commercial and 3 were cultivars. The Wricke and Purchase et al. methods were highly consistent in identifying individuals with low ...
Doyle David Matthew DM Department of Psychology, 2007 Percival Stern Hall, Tulane University, New Orleans, LA, 70118, USA, - - 2014
Approaching the inverse association between perceived discrimination and close relationship functioning from a stress and coping framework, we propose and test a novel model incorporating psychological (emotion dysregulation) and physiological (chronic inflammation) pathways. Analyses of data from a sample of African American participants (N = 592) enrolled in the Midlife in the ...
Giner Lucas L Departamento de Psiquiatría, Facultad de Medicina, Universidad de Sevilla, Sevilla, España. Electronic address: - - 2014
To be able to prevent suicides, The exact magnitude of suicides must be known in order to prevent them. There is evidence that data provided on the number of suicides by the Spanish Statistical Office (Instituto Nacional de Estadística [INE]) differs from that identified by forensic pathologists. This paper aims ...
Khalil Hussein H Department of Zoology, Stockholm University, 10691, Stockholm, Sweden, - - 2014
Apex predators play an important role in shaping ecosystem structure. They may suppress smaller predators (mesopredators) but also subsidize scavengers via carrion provisioning. However, the importance of these interactions can change with ecosystem context. The wolverine (Gulo gulo) is a cold-adapted carnivore and facultative scavenger. It has a circumboreal distribution, ...
Gizaw Solomon S Debre Birhan Agricultural Research Centre, P.O. Box 112, Debre Birhan, Ethiopia, - - 2014
Pedigree recording and genetic selection in village flocks of smallholder farmers have been deemed infeasible by researchers and development workers. This is mainly due to the difficulty of sire identification under uncontrolled village breeding practices. A cooperative village sheep-breeding scheme was designed to achieve controlled breeding and implemented for Menz ...
Corberán-Vallet Ana A 1Department of Statistics and Operations Research, University of Valencia, Burjassot, - - 2014
In this paper, we describe a Bayesian hierarchical Poisson model for the prospective analysis of data for infectious diseases. The proposed model consists of two components. The first component describes the behavior of disease during nonepidemic periods and the second component represents the increase in disease counts due to the ...
Kermany Amir R AR Department of Human Genetics, 920 E 58th Street, University of Chicago, Chicago, IL 60637, - - 2014
An estimated 10-30% of clinically recognized conceptions are aneuploid, leading to spontaneous miscarriages, IVF failures and, when viable, severe developmental disabilities. With the ongoing reduction in the cost of genotyping and DNA sequencing, the use of high density SNP markers for clinical diagnosis of aneuploidy and biomedical research into its ...
Murphy Adrianna A European Centre on Health of Societies in Transition (ECOHOST), Department of Health Services Research and Policy, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, - - 2014
The purpose of this study was to assess whether alcohol-related community characteristics act collectively to influence individual-level alcohol consumption in the former Soviet Union (fSU). Using multi-level data from nine countries in the fSU we conducted a factor analysis of seven alcohol-related community characteristics. The association between any latent factors ...
Commisso María S - - 2014
A finite element model of the temporomandibular joint (TMJ) and the human mandible was fabricated to study the effect of abnormal loading, such as awake and asleep bruxism, on the articular disc. A quasilinear viscoelastic model was used to simulate the behaviour of the disc. The viscoelastic nature of this ...
Yörük Barış K BK Department of Economics, University at Albany, SUNY, 1400 Washington Avenue, Albany, NY 12222, United States. Electronic address: - - 2014
Underage drinkers often use false identification to purchase alcohol or gain access into bars. In recent years, several states have introduced laws that provide incentives to retailers and bar owners who use electronic scanners to ensure that the customer is 21 years or older and uses a valid identification to ...
Verhulst Brad B Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine (VCU), Box 980126, Richmond, VA, 23298-0126, USA, - - 2014
Twin and family studies implicitly assume that the covariation between family members remains constant across differences in age between the members of the family. However, age-specificity in gene expression for shared environmental factors could generate higher correlations between family members who are more similar in age. Cohort effects (cohort × genotype or ...
Holmes Philip P Department of Mechanical and Aerospace Engineering, Princeton University; Program in Applied and Computational Mathematics, Princeton University; Princeton Neuroscience Institute, Princeton - - 2014
We review how leaky competing accumulators (LCAs) can be used to model decision making in two-alternative, forced-choice tasks, and we show how they reduce to drift diffusion (DD) processes in special cases. As continuum limits of the sequential probability ratio test, DD processes are optimal in producing decisions of specified ...
Schwabe Inga I Department of Research Methodology, Measurement, and Data Analysis, University of Twente, Drienerlolaan 5, 7522 NB,  Enschede, The Netherlands, - - 2014
Considerable effort has been devoted to establish genotype by environment interaction (G [Formula: see text] E) in case of unmeasured genetic and environmental influences. Although it has been outlined by various authors that the appearance of G [Formula: see text] E can be dependent on properties of the given measurement ...
Steiling W W Henkel AG & Co KGaA, Henkelstr. 67, D-40191 Düsseldorf, Germany. Electronic address: - - 2014
In recent years, the official regulation of chemicals and chemical products has been intensified. Explicitly for spray products enhanced requirements to assess the consumers'/professionals' exposure to such product type have been introduced. In this regard the Aerosol-Dispensers-Directive (75/324/EEC) with obligation for marketing aerosol dispensers, and the Cosmetic-Products-Regulation (1223/2009/EC) which obliges ...
Shaw William S WS Liberty Mutual Research Institute for Safety, 71 Frankland Road, Hopkinton, MA, 01748, USA, - - 2014
Introduction An employer offer of temporary job modification is a key strategy for facilitating return-to-work for musculoskeletal conditions, but there are no validated scales to assess the level of support for temporary job modifications across a range of job types and organizations. Objective To pilot test a new 21-item self-report ...
Xia Yang Y Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, - - 2014
Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) was measured in all participants aged 6 years and older from the Centers for Disease Control and Prevention's National Health and Nutrition Examination Survey 2007-2008. The suitability of using creatinine or specific gravity for urinary NNAL correction in exposure assessment is examined in this study. Effects ...
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