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Gilbert Kimberly J KJ Department of Zoology, University of British Columbia, 6270 University Blvd., Vancouver, BC, V6T 1Z4, - - 2014
QST , a measure of quantitative genetic differentiation among populations, is an index that can suggest local adaptation if QST for a trait is sufficiently larger than the mean FST of neutral genetic markers. A previous method by Whitlock and Guillaume derived a simulation resampling approach to statistically test for ...
MacNamara Shev S Massachusetts Institute of Technology, Cambridge, MA 02139. Electronic address: - - 2014
The role of mathematical models of signaling networks is showcased by examples from Drosophila development. Three models of consecutive stages in dorsoventral patterning are presented. We begin with a compartmental model of intracellular reactions that generates a gradient of nuclear-localized Dorsal, exhibiting constant shape and dynamic amplitude. A simple thermodynamic ...
Shevlin Mark M University of Ulster at Magee, L'Derry, Northern Ireland - - 2014
This study assessed the dimensional structure of the UCLA Loneliness Scale ([UCLA-LS], UCLA-3). Data from the Northern Ireland Young Life and Times Survey (2011), a survey of 1,434 16-year-olds, was used to examine the underlying factor structure of the scale. Confirmatory factor analysis was employed to compare alternative factor analytical ...
Xu Chang - - 2014
The purpose of the present study was to examine factors that influence strategic flexibility in computational estimation for Chinese- and Canadian-educated adults. Strategic flexibility was operationalized as the percentage of trials on which participants chose the problem-based procedure that best balanced proximity to the correct answer with simplification of the ...
Panda Suchita - - 2014
Over the last decade our understanding of human gut microbiology underwent a tremendous transformation. The limitations of culture-based methods have given way to Next Generation Sequencing techniques, allowing us to understand the microbial gut community in greater depth. The human GI-tract harbours one of the most complex and abundant ecosystems ...
Song Minsun M Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20850, - - 2014
Risk-prediction models need careful calibration to ensure they produce unbiased estimates of risk for subjects in the underlying population given their risk-factor profiles. As subjects with extreme high or low risk may be the most affected by knowledge of their risk estimates, checking the adequacy of risk models at the ...
Al-Hebshi N N NN Department of Preventive Dentistry-Periodontology, Faculty of Dentistry, Jazan University, Jazan, Saudi - - 2014
A number of species/phylotypes have been newly implicated as putative periopathogens. The objective of this study was to explore associations among classical and new pathogens in subgingival biofilm and to assess their relative importance to chronic periodontitis. Pooled subgingival biofilm samples were obtained from 40 patients with chronic periodontitis and ...
Rimmer Andy A 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. - - 2014
High-throughput DNA sequencing technology has transformed genetic research and is starting to make an impact on clinical practice. However, analyzing high-throughput sequencing data remains challenging, particularly in clinical settings where accuracy and turnaround times are critical. We present a new approach to this problem, implemented in a software package called ...
Acar Evrim - - 2014
Analysis of data from multiple sources has the potential to enhance knowledge discovery by capturing underlying structures, which are, otherwise, difficult to extract. Fusing data from multiple sources has already proved useful in many applications in social network analysis, signal processing and bioinformatics. However, data fusion is challenging since data ...
Chen Wenan W Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of - - 2014
Recently, Wen and Stephens (Wen and Stephens [2010] Ann Appl Stat 4(3):1158-1182) proposed a linear predictor, called BLIMP, that uses conditional multivariate normal moments to impute genotypes with accuracy similar to current state-of-the-art methods. One novelty is that it regularized the estimated covariance matrix based on a model from population ...
Gonçalves Caroline M - - 2014
In Brazil, dengue epidemics erupt sporadically throughout the country and it is unclear if outbreaks may initiate a sustainable transmission cycle. There are few studies evaluating the ability of Brazilian Aedes aegypti populations to transmit dengue virus (DENV). The aim of this study was to compare DENV susceptibility of field-captured ...
Ramayah T T School of Management, Universiti Sains Malaysia, Penang, - - 2014
There is a belief that academics tend to hold on tightly to their knowledge and intellectual resources. However, not much effort has been put into the creation of a valid and reliable instrument to measure knowledge sharing behavior among the academics. To apply and validate the Knowledge Sharing Behavior Scale ...
Leblois Raphaël R INRA, UMR 1062 CBGP (INRA-IRD-CIRAD-Montpellier Supagro), Montpellier, FranceMuséum National d'Histoire Naturelle, CNRS, UMR OSEB, Paris, FranceInstitut de Biologie Computationnelle, Montpellier, France - - 2014
Understanding the demographic history of populations and species is a central issue in evolutionary biology and molecular ecology. In the present work, we develop a maximum likelihood method for the inference of past changes in population size from microsatellite allelic data. Our method is based on importance sampling of gene ...
Alver Y Y Department of Civil Engineering, Ege University, Izmir, Turkey. Electronic address: - - 2014
Young drivers' high traffic violation involvement rate and significant contribution to traffic crashes compared to older drivers creates the need for detailed analyses of factors affecting young drivers' behaviors. This study is based on survey data collected from 2,057 18-29 year old young adults. Data were collected via face-to-face questionnaire ...
Liu Z Z Vereinigte Informationssysteme Tierhaltung w.V. (VIT), Heideweg 1, D-27283 Verden, Germany. Electronic address: - - 2014
Compared with the currently widely used multi-step genomic models for genomic evaluation, single-step genomic models can provide more accurate genomic evaluation by jointly analyzing phenotypes and genotypes of all animals and can properly correct for the effect of genomic preselection on genetic evaluations. The objectives of this study were to ...
Hermann Robert R Montanuniversitaet Leoben, Leoben, Austria - - 2014
For the first time, basic technical and economic studies for landfill mining are being carried out in Austria on the basis of a pilot project. An important goal of these studies is the collection of elementary data as the basis for an integrated ecological and economic assessment of landfill mining ...
Khansefid M M Department of Environment and Primary Industries, AgriBio, 5 Ring Road, Bundoora, VIC 3083, Australia Dairy Futures Cooperative Research Centre (CRC), AgriBio, 5 Ring Road, Bundoora, VIC 3083, Australia Department of Agriculture and Food Systems, Melbourne School of Land and Environment, The University of Melbourne, Parkville, VIC 3010, Australia - - 2014
Residual feed intake (RFI) is a measure of the efficiency of animals in feed utilization. The accuracies of genomic EBVs (GEBVs) for RFI could be improved by increasing the size of the reference population. Combining RFI records of different breeds is a way to do that. The aims of this ...
Szpiech Zachary A ZA Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA - - 2014
Haplotype-based scans to detect natural selection are useful to identify recent or ongoing positive selection in genomes. As both real and simulated genomic datasets grow larger, spanning thousands of samples and millions of markers, there is a need for a fast and efficient implementation of these scans for general use. ...
Duangjit Sureewan S Faculty of Pharmacy, Silpakorn - - 2014
A nonlinear response surface method incorporating multivariate spline interpolation (RSM-S) is a useful technique for the optimization of pharmaceutical formulations, although the direct reliability of the optimal formulation must be evaluated. In this study, we demonstrated the feasibility of using the bootstrap (BS) resampling technique to evaluate the direct reliability ...
Rañola John Michael JM Department of Statistics, University of Washington - - 2014
Unique modeling and computational challenges arise in locating the geographic origin of individuals based on their genetic backgrounds. SNPs vary widely in informativeness, allele frequencies change nonlinearly with geography, and reliable localization requires evidence to be integrated across a multitude of SNPs. These problems become even more acute for individuals ...
Maciejewski Wes W The University of British Columbia, Mathematics, 1984 Mathematics Road, Vancouver, British Columbia, Canada V6T - - 2014
Understanding the influence of an environment on the evolution of its resident population is a major challenge in evolutionary biology. Great progress has been made in homogeneous population structures while heterogeneous structures have received relatively less attention. Here we present a structured population model where different individuals are best suited ...
Chen Shyi-Ming - - 2014
In this paper, we present a new method for fuzzy forecasting based on two-factors second-order fuzzy-trend logical relationship groups and the probabilities of trends of fuzzy-trend logical relationships. Firstly, the proposed method fuzzifies the historical training data of the main factor and the secondary factor into fuzzy sets, respectively, to ...
Chaturvedi Nimisha - - 2014
A number of statistical models has been proposed for studying the association between geneexpression and copy number data in integrated analysis. The next step is to compare associationpatterns between different groups of samples. We propose a method, named dSIM, to find differences in association between copy number and geneexpression, when ...
Pissis Solon P - - 2014
Identifying repeated factors that occur in a string of letters or common factors that occur in a setof strings represents an important task in computer science and biology. Such patterns are calledmotifs, and the process of identifying them is called motif extraction. In biology, motif extractionconstitutes a fundamental step in ...
Vilseck Jonah Z JZ Department of Chemistry, Yale University , New Haven, Connecticut 06520-8107, United - - 2014
The recently developed Charge Model 5 (CM5) is tested for its utility in condensed-phase simulations. The CM5 approach, which derives partial atomic charges from Hirshfeld population analyses, provides excellent results for gas-phase dipole moments and is applicable to all elements of the periodic table. Herein, the adequacy of scaled CM5 ...
McCullough Erin L EL Division of Biological Sciences, University of Montana, Missoula, MT, USA - - 2014
The horns of giant rhinoceros beetles are a classic example of the elaborate morphologies that can result from sexual selection. Theory predicts that sexual traits will evolve to be increasingly exaggerated until survival costs balance the reproductive benefits of further trait elaboration. In Trypoxylus dichotomus, long horns confer a competitive ...
Leontyev Igor V IV Department of Chemistry, University of California Davis, One Shields Avenue, Davis, California 95616, - - 2014
Earlier, using phenomenological approach, we showed that in some cases polarizable models of condensed phase systems can be reduced to nonpolarizable equivalent models with scaled charges. Examples of such systems include ionic liquids, TIPnP-type models of water, protein force fields, and others, where interactions and dynamics of inherently polarizable species ...
Olatunji Bunmi O BO Vanderbilt University, Nashville, TN, USA - - 2014
The current research evaluated a bifactor model for the Disgust Emotion Scale (DES) in three samples: N = 1,318 nonclinical participants, N = 152 clinic-referred patients, and N = 352 nonclinical participants. The primary goals were to (a) use bifactor modeling to examine the latent structure of the DES and ...
Gerrard Paul P Spaulding Rehabilitation Hospital and Harvard Medical School, Boston, - - 2014
To investigate the neurobehavioral pattern of recovery of consciousness as reflected by performance on the subscales of the Coma Recovery Scale - Revised (CRS-R). Retrospective item response theory and factor analysis. Inpatient rehabilitation facilities in the United States and Europe. Rehabilitation inpatients (N=180) with post-traumatic disturbance in consciousness who participated ...
Bandyopadhyay Uttam U Department of Statistics, University of Calcutta, Kolkata, West Bengal, 700035, - - 2014
Matched case-control paired data are commonly used to study the association between a disease and an exposure of interest. This work provides a consistent test for this association with respect to the conditional odds ratio (ORc), which is a measure of association that is also valid in prospective studies. We ...
Cabras Stefano S Department of Statistics, Universidad Carlos III de Madrid, Getafe, Spain; Department of Mathematics and Informatics, Università di Cagliari, Cagliari, - - 2014
This paper considers the problem of selecting a set of regressors when the response variable is distributed according to a specified parametric model and observations are censored. Under a Bayesian perspective, the most widely used tools are Bayes factors (BFs), which are undefined when improper priors are used. In order ...
Dixon Josie J Personal Social Services Research Unit, London School of Economics, London, - - 2014
This paper examines the numbers of people with dementia who could be diagnosed and the likely cost-effectiveness of a one-off screen for dementia for people aged 75 years in England and Wales. The study uses static decision modelling to compare a one-off screen for dementia with a no-screen scenario. Estimates for ...
Sesé-Abad Albert A Balearic Islands University, Palma, - - 2014
Evidence-based practice may be implemented more successfully if the barriers to its implementation have been previously identified. Many of the available instruments to measure these barriers have been validated in single samples or without confirmatory analyses. The objective of the study was to contrast the goodness of fit of two ...
Wang Kai K Department of Industrial and Management System Engineering, West Virginia University , Morgantown, West Virginia 26506, United - - 2014
One of the most fundamental steps in risk assessment is to quantify the exposure-response relationship for the material/chemical of interest. This work develops a new statistical method, referred to as SKQ (stochastic kriging with qualitative factors), to synergistically model exposure-response data, which often arise from multiple sources (e.g., laboratories, animal ...
Cayuela Hugo H Laboratoire d'Ecologie des Hydrosystèmes Naturels et Anthropisés, Université Lyon I, CNRS, UMR 5023, 69622, Villeurbanne, France, - - 2014
Iteroparity is an adaptive response to uncertainty in reproductive success. However, spreading reproductive success over multiple reproduction events during a lifetime is constrained by adult mortality and the stochasticity associated with interactions between external factors and physiological states. The acquisition of information about environmental conditions during the growth of progeny ...
Mitchell R J RJ a Transport and Road Safety (TARS) Research , University of New South Wales , Sydney , - - 2014
Various human factors classification frameworks have been used to identified causal factors for clinical adverse events. A systematic review was conducted to identify human factors classification frameworks that identified the causal factors (including human error) of adverse events in a hospital setting. Six electronic databases were searched, identifying 1997 articles ...
Fessler Daniel M T DM Department of Anthropology and Center for Behavior, Evolution, and Culture, University of California, 341 Haines Hall, Los Angeles, CA, 90095-1553, USA, - - 2014
Across taxa, strength and size are elementary determinants of relative fighting capacity; in species with complex behavioral repertoires, numerous additional factors also contribute. When many factors must be considered simultaneously, decision-making in agonistic contexts can be facilitated through the use of a summary representation. Size and strength may constitute the ...
Rowsey Ross R School of Molecular Biosciences and Center for Reproductive Biology, Washington State University, Pullman, WA 99164, - - 2014
The most important risk factor for human aneuploidy is increasing maternal age, but the basis of this association remains unknown. Indeed, one of the earliest models of the maternal-age effect-the "production-line model" proposed by Henderson and Edwards in 1968-remains one of the most-cited explanations. The model has two key components: ...
Béchaux Camille C ANSES, French Agency for Food, Environmental and Occupational Health Safety, 27-31 Avenue du Général Leclerc, 94701 Maisons-Alfort, France. Electronic address: - - 2014
As cadmium accumulates mainly in kidney, urinary concentrations are considered as relevant data to assess the risk related to cadmium. The French Nutrition and Health Survey (ENNS) recorded the concentration of cadmium in the urine of the French population. However, as with all biomonitoring data, it needs to be linked ...
Béchaux Camille - - 2014
Abstract New data are available in the field of risk assessment: the biomonitoring data which is measurement of the chemical dose in a human tissue (e.g. blood or urine). These data are original because they represent direct measurements of the dose of chemical substances really taken up from the environment, ...
Lemons P R PR U.S. Fish and Wildlife Service, Marine Mammals Management, 1011 East Tudor Road, Anchorage, AK, 99503, - - 2014
Genotypes are frequently used to assess alternative reproductive strategies such as extra-pair paternity and conspecific brood parasitism in wild populations. However, such analyses are vulnerable to genotyping error or molecular artefacts that can bias results. For example, when using multilocus microsatellite data, a mismatch at a single locus, suggesting the ...
Zanoli Raffaele R Dipartimento di Scienze Agrarie, Alimentari e Ambientali (D3A), Università Politecnica delle Marche, Ancona, - - 2014
Certification is an essential feature in organic farming, and it is based on inspections to verify compliance with respect to European Council Regulation-EC Reg. No 834/2007. A risk-based approach to noncompliance that alerts the control bodies to activate planning inspections would contribute to a more efficient and cost-effective certification system. ...
Wahl Simone - - 2014
With the help of epigenome-wide association studies (EWAS), increasing knowledge on the role of epigenetic mechanisms such as DNA methylation in disease processes is obtained. In addition, EWAS aid the understanding of behavioral and environmental effects on DNA methylation. In terms of statistical analysis, specific challenges arise from the characteristics ...
Darlay Rebecca R School of Biology, Miall Building, University of Leeds, Leeds LS2 9JT, UK. Electronic address: - - 2014
Foetal death, or abortion at term, in sheep is of major significance to the livestock industry, accounting for more than £24million lost per annum. We have investigated whether there is a genetic component to abortion within two flocks of pedigree Charollais sheep, one followed from 1989 to 2006, the other ...
Tsuruta S S Animal and Dairy Science Department, University of Georgia, Athens 30602. Electronic address: - - 2014
Assigning unknown parent groups (UPG) in mixed-model equations using single-step genomic BLUP was investigated to reduce bias and to increase accuracy in genomic estimated breeding values (GEBV). The original UPG were defined based on the animal's birth year and the sex of the animal's unknown parents. Combining the last 2 ...
Abrams Steven S Interuniversity Institute for Biostatistics and statistical Bioinformatics, Hasselt University, Agoralaan 1 Gebouw D, B3590 Diepenbeek, Belgium - - 2014
In recent years, it has been shown that individual heterogeneity in the acquisition of infectious diseases has a large impact on the estimation of important epidemiological parameters such as the (basic) reproduction number. Therefore, frailty modeling has become increasingly popular in infectious disease epidemiology. However, so far, using frailty models, ...
Gao H H Institute of Animal Sciences, Chinese Academy of Agricultural Science, Beijing, People's Republic of - - 2014
Given the drawbacks of implementing multivariate analysis for mapping multiple traits in genome-wide association study (GWAS), principal component analysis (PCA) has been widely used to generate independent 'super traits' from the original multivariate phenotypic traits for the univariate analysis. However, parameter estimates in this framework may not be the same ...
Kumar Paulraj Ranjith PR Department of Electronics and Communication, PSR Engineering College, Sivakasi, - - 2014
Coronary artery disease due to atherosclerosis is an epidemic in India. An estimated 1.3 million Indians died from this in 2000. The projected death from coronary artery disease by 2016 is 2.98 million.OBJECTIVE: To build an effective model which assorts the individuals, whether they belong to the normal group, risk ...
Stefanile Cristina C Department of Health Sciences, Section of Psychology, University of Florence, Via di San Salvi, 12, Pad. 26, 50135 Florence, Italy. Electronic address: - - 2014
The current study examined the validity of the Italian version of the Acceptance of Cosmetic Surgery Scale (ACSS; Henderson-King & Henderson-King, 2005) in a sample of 378 Italian adult women. A series of confirmatory factor analyses were conducted. A three-factor solution provided the best fit to the data and confirmed ...
Xu Yihuan Y ImClone LLC, A Wholly Owned Subsidiary of Eli Lilly and Company, 440 Route 22, Bridgewater, NJ - - 2014
The g - and - h distributional family is generated from a relatively simple transformation of the standard normal and can approximate a broad spectrum of distributions. Consequently, it is easy to use in simulation studies and has been applied in multiple areas, including risk management, stock return analysis and ...
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