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Lin Wan-Yu WY Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, - - 2014
Biological evidence suggests that multiple causal variants in a gene may cluster physically. Variants within the same protein functional domain or gene regulatory element would locate in close proximity on the DNA sequence. However, spatial information of variants is usually not used in current rare variant association analyses. We here ...
Zhao Xing X West China School of Public Health, Sichuan University, Chengdu 610041, China. - - 2014
It is valuable to study the spatiotemporal pattern of Japanese encephalitis (JE) and its association with the contextual risk factors in southwest China, which is the most endemic area in China. Using data from 2004 to 2009, we applied GISmapping and spatial autocorrelation analysis to analyze reported incidence data of ...
Lei Yongdeng Y State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, No.19, Xinjiekouwai Street, Haidian District, Beijing, 100875, - - 2013
Globally, more people and assets are concentrated on the limited coastal plains where they are exposed to frequent disasters, such as typhoons, rainstorms, and floods that often result in tremendous casualties and economic losses. Based on the causal analysis of the historical typhoon cases in the Guangdong Province of China, ...
Imran Mudassar M Lahore University of Management Sciences, Sector U DHA, Lahore, Pakistan, - - 2013
In this paper, we present a rigorous mathematical analysis of a deterministic model for the transmission dynamics of hepatitis C. The model is suitable for populations where two frequent modes of transmission of hepatitis C virus, namely unsafe blood transfusions and intravenous drug use, are dominant. The susceptible population is ...
Gazave Elodie E Departments of Biological Statistics and Computational Biology and Molecular Biology and Genetics, Cornell University, Ithaca, NY - - 2013
Human populations have experienced dramatic growth since the Neolithic revolution. Recent studies that sequenced a very large number of individuals observed an extreme excess of rare variants and provided clear evidence of recent rapid growth in effective population size, although estimates have varied greatly among studies. All these studies were ...
Demetrashvili Nino - - 2013
Many QTL studies have two common features: (1) often there is missing marker information, (2) among many markers involved in the biological process only a few are causal. In statistics, the second issue falls under the headings "sparsity" and "causal inference". The goal of this work is to develop a ...
Belushkin M M Philip Morris International R&D, Philip Morris Products S.A., Rue des Usines 90, 2000 Neuchâtel, Switzerland. Electronic address: - - 2013
A wealth of in vitro toxicological information on different types of tobaccos and tobacco products has been acquired and published, although the link between in vitro data and impact on human health remains elusive. The present study investigates the possibility of establishing quantitative models for the in vitro toxicological endpoint ...
Baldissera Sandro S National Centre of Epidemiology, Surveillance and Health Promotion, National Institute of Public Health, Rome, - - 2013
Field substitution of nonrespondents can be used to maintain the planned sample size and structure in surveys but may introduce additional bias. Sample weighting is suggested as the preferable alternative; however, limited empirical evidence exists comparing the two methods. We wanted to assess the impact of substitution on surveillance results ...
Chen Yu Y Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI 48109, United - - 2014
Injury resulting from motor vehicle crashes is the leading cause of death among teenagers in the US. Few programs or policies have been found to be effective in reducing the risk of fatal car crashes for young novice drivers. One effective policy that has been widely implemented is Graduated Driver ...
Lawrence David W DW *Faculty of Medicine, University of Toronto, Toronto, Canada; †David L. MacIntosh Sport Medicine Clinic, Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, Canada; ‡Division of Neurosurgery, Injury Prevention Research Office, Keenan Research Centre, St Michael's Hospital, University of Toronto, Toronto, Canada; and §University of Toronto, Toronto, - - 2013
Interrater agreement evaluation of a tool to document and code the situational factors and mechanisms of knockouts (KOs) and technical knockouts (TKOs) in mixed martial arts (MMA). Retrospective case series. Professional MMA matches from the Ultimate Fighting Championship-2006-2012. Two nonmedically trained independent raters. The MMA Knockout Tool (MMA-KT) consists of ...
He Yangcheng Y MOE-Microsoft Laboratory for Intelligent Computing and Intelligent Systems, Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200240, PR China. Electronic address: - - 2013
Concept factorization (CF) is a variant of non-negative matrix factorization (NMF). In CF, each concept is represented by a linear combination of data points, and each data point is represented by a linear combination of concepts. More specifically, each concept is represented by more than one data point with different ...
Camacho Guillermo A - - 2013
The information of electromyographic signals can be used by Myoelectric Control Systems (MCSs) to actuate prostheses. These devices allow the performing of movements that cannot be carried out by persons with amputated limbs. The state of the art in the development of MCSs is based on the use of individual ...
Tierney Laura T LT Faculty of Nursing, Midwifery & Health, University of Technology, Sydney, Australia. Electronic address: - - 2013
In intensive care, occupancy is a commonly used measure. There is inconsistency however in its measurement and optimal occupancy targets need to be defined. The objectives of this literature review were to explore how occupancy is measured, reported, and interpreted and investigate optimal occupancy levels for ICUs. A literature search ...
Nielsen Martin Reinhardt MR Department of Food and Resource Economics, University of Copenhagen, Rolighedsvej 23, 1958 Frederiksberg C, Denmark; Centre for Macroecology, Evolution and Climate, University of Copenhagen, Universitetsparken 15, 2100 Copenhagen Ø, - - 2013
Regulation of illegal bushmeat trade is a major conservation challenge in Africa. We investigated what factors are most likely to induce actors in the bushmeat trade to shift to an alternative occupation by conducting a choice experiment with 325 actors in the bushmeat trade in the Kilombero Valley, Tanzania. Specifically, ...
Cope R C RC School of Biological Science, The University of Queensland, St Lucia, Queensland, 4072, - - 2013
For wildlife populations it is often difficult to determine biological parameters that indicate breeding patterns and population mixing, but knowledge of these parameters is essential for effective management. A pedigree encodes the relationship between individuals, and can provide insight into the dynamics of a population over its recent history. Here, ...
Hartman Rosemary R Graduate Group in Ecology, University of California, Davis, One Shields Avenue, Davis, CA, 95616, U.S.A.. - - 2013
Habitat characteristics mediate predator-prey coexistence in many ecological systems but are seldom considered in species introductions. When economically important introduced predators are stocked despite known negative impacts on native species, understanding the role of refuges, landscape configurations, and community interactions can inform habitat management plans. We measured these factors in ...
Eserman Lauren A LA Plant Biology Department, University of Georgia, Athens, Georgia 30602 - - 2013
Morning glories are an emerging model system, and resolving phylogenetic relationships is critical for understanding their evolution. Phylogenetic studies demonstrated that the largest morning glory genus, Ipomoea, is not monophyletic, and nine other genera are derived from within Ipomoea. Therefore, systematic research is focused on the monophyletic tribe Ipomoeeae (ca. ...
Nakano Yoshio Y Department of Chemistry, Nihon University School of Dentistry, 1-8-13 Kanda-Surugadai, Chuo-ku, Tokyo 101-8310, Japan. Electronic address: - - 2013
This study presents an effective method of classifying oral malodor from oral microbiota in saliva by using a support vector machine (SVM), an artificial neural network (ANN), and a decision tree. This approach uses concentrations of methyl mercaptan in mouth air as an indicator of oral malodor, and peak areas ...
Zhao Zeng-Hui ZH State Key Laboratory of Mining Disaster Prevention and Control Cofounded by Shandong Province and the Ministry of Science and Technology, Qingdao, Shandong 266590, China ; College of Civil Engineering of Shandong University of Science and Technology, Qingdao, Shandong 266590, - - 2013
According to the geological characteristics of Xinjiang Ili mine in western area of China, a physical model of interstratified strata composed of soft rock and hard coal seam was established. Selecting the tunnel position, deformation modulus, and strength parameters of each layer as influencing factors, the sensitivity coefficient of roadway ...
Norwalk Kate E KE Department of Educational and School Psychology, The Pennsylvania State University, USA. Electronic address: - - 2014
Despite growing interest in early intervention, there are few measures available to monitor the progress of early academic skills in preschoolers. The Early Arithmetic, Reading, and Learning Indicators (EARLI; DiPerna, Morgan, & Lei, 2007) were developed as brief assessments of critical early literacy and numeracy skills. The purpose of the ...
Caley Michael Julian MJ Australian Institute of Marine Science PMB 3, Townsville, Qld, 4810, - - 2014
Expert knowledge is a valuable source of information with a wide range of research applications. Despite the recent advances in defining expert knowledge, little attention has been given to how to view expertise as a system of interacting contributory factors for quantifying an individual's expertise. We present a systems approach ...
Eager Eric Alan EA Mathematics Department, University of Wisconsin La Crosse, 1020 Cowley Hall, 1725 State Street, La Crosse, WI, USA. Electronic address: - - 2013
Sink populations are doomed to decline to extinction in the absence of immigration. The dynamics of sink populations are not easily modelled using the standard framework of per capita rates of immigration, because numbers of immigrants are determined by extrinsic sources (for example, source populations, or population managers). Here we ...
Moulard Odilie O Oncology-Global Evidence and Value Development, Medical Affairs, Sanofi, Cambridge, MA, - - 2013
Primary myelofibrosis (PMF), essential thrombocythemia (ET), and polycythemia vera (PV) are BCR ABL negative myeloproliferative neoplasms (MPN). Published epidemiology data are scarce and multiple sources are needed in order to assess the disease burden. We assembled the most recent information available on the incidence and prevalence of MF, ET and ...
Tatinati Sivanagaraja S School of Electronics Engineering, College of IT Engineering, Kyungpook National University, Daegu, Republic of - - 2013
We propose a hybrid method for forecasting the wind speed. The wind speed data is first decomposed into intrinsic mode functions (IMFs) with empirical mode decomposition. Based on the partial autocorrelation factor of the individual IMFs, adaptive methods are then employed for the prediction of IMFs. Least squares-support vector machines ...
Huang Kang K Key Laboratory of Resource Biology and Biotechnology in Western China of Ministry of Education, and College of Life Sciences, Northwest University, Xi'an, ShaanXi, 710069, - - 2013
Studies in genetics and ecology often require estimates of relatedness coefficients based on genetic marker data. Many diploid estimators have been developed using either method-of-moments or maximum-likelihood estimates. However, there are no relatedness estimators for polyploids. The development of a moment estimator for polyploids with polysomic inheritance, which simultaneously incorporates ...
Walsh Ian I Department of Biology, University of Padua, Viale G. Colombo 3, 35131, Padua, Italy, - - 2013
Post-translational modification of protein lysines was recently shown to be a common feature of eukaryotic organisms. The ubiquitin modification is regarded as a versatile regulatory mechanism with many important cellular roles. Large-scale datasets are becoming available for H. sapiens ubiquitination. However, using current experimental techniques the vast majority of their ...
Estabrook Ryne - - 2013
While measurement evaluation has been embraced as an important step in psychological research, evaluating measurement structures with longitudinal data is fraught with limitations. This article defines and tests a measurement model of derivatives (MMOD), which is designed to assess the measurement structure of latent constructs both for analyses of between-person ...
Gunasekara Fiona Imlach FI Health Inequalities Research Programme, Department of Public Health, University of Otago, Wellington, New - - 2013
The analysis of repeated measures or panel data allows control of some of the biases which plague other observational studies, particularly unmeasured confounding. When this bias is suspected, and the research question is: 'Does a change in an exposure cause a change in the outcome?', a fixed effects approach can ...
Rojas Stephanie L - - 2013
The current study tests the convergent and discriminant validity of a modified version of the Five Factor Model Rating Form (FFMRF), a one-page, brief measure of the five-factor model. The Five Factor Form (FFF) explicitly identifies maladaptive variants for both poles of each of the 30 facets of the FFMRF. ...
Falkenbach Diana M - - 2013
Psychopathy is a personality construct typically related to deficits in interpersonal and affective functioning and antisocial behavior. Currently, the majority of research focuses on the omnibus construct of psychopathy as it applies to criminal populations. However, theories of psychopathy and empirical evidence suggest that there may be different variants of ...
Layeghifard Mehdi - - 2013
The advent of molecular biology techniques and constant increase in availability of genetic material have triggered the development of many phylogenetic tree inference methods. However, several reticulate evolution processes, such as horizontal gene transfer and hybridization, have been shown to blur the species evolutionary history by causing discordance among phylogenies ...
Zhang Qiuwen Q College of Hydropower and Information Engineering, Huazhong University of Science and Technology, Wuhan 430074, China ; School of Municipal and Geomatics Engineering, Hunan City University, Yiyang 413000, - - 2013
Groundwater contamination is a serious threat to water supply. Risk assessment of groundwater contamination is an effective way to protect the safety of groundwater resource. Groundwater is a complex and fuzzy system with many uncertainties, which is impacted by different geological and hydrological factors. In order to deal with the ...
Putnam Patrick P - - 2013
In recent years genetic data analysis has seen a rapid increase in the scale of data to be analyzed. Schadt et al [1] offered that with data sets approaching the petabyte scale, data related challenges such as formatting, management, and transfer are increasingly important topics which need to be addressed. ...
Lichev Vladimir V Department of Psychosomatic Medicine and Psychotherapy, University of Leipzig, Leipzig, - - 2013
The aim of this study was to evaluate psychometric properties and relations between two different methods of measuring alexithymia and one measure of emotional awareness in a German non-clinical sample. The 20-Item Toronto Alexithymia Scale (TAS-20), the Toronto Structured Interview for Alexithymia (TSIA), and the Levels of Emotional Awareness Scale ...
Chang Lun-Ching - - 2013
As high-throughput genomic technologies become accurate and affordable, an increasing number of data sets have been accumulated in the public domain and genomic information integration and meta-analysis have become routine in biomedical research. In this paper, we focus on microarray meta-analysis, where multiple microarray studies with relevant biological hypotheses are ...
Hu Yu Y Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA and Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, - - 2013
Correctly estimating isoform-specific gene expression is important for understanding complicated biological mechanisms and for mapping disease susceptibility genes. However, estimating isoform-specific gene expression is challenging because various biases present in RNA-Seq (RNA sequencing) data complicate the analysis, and if not appropriately corrected, can affect isoform expression estimation and downstream analysis. ...
Vitalis Renaud R INRA; Institut de Biologie - - 2013
The recent advent of high throughput sequencing and genotyping technologies makes it possible to produce, easily and cost-effectively, large amounts of detailed data on the genotype composition of populations. Detecting locus-specific effects may help identify those genes that have been, or are currently, targeted by natural selection. How best to ...
Vanderelst Dieter - - 2013
Many studies have assessed the level of bed net coverage in populations at risk of malaria infection. These revealed large variations in bed net use across countries, regions and social strata. Such studies are often aimed at identifying populations with low access to bed nets that should be prioritized in ...
Scraggs E E Department of Animal Sciences, Washington State University, Pullman, WA, - - 2013
The objective of this research was to examine the population structure of full-blood (100%) Wagyu cattle registered in the United States with the American Wagyu Association, with the aim of estimating and comparing the levels of inbreeding from both pedigree and genotypic data. A total of 4132 full-blood Wagyu cattle ...
Simon Chihanga - - 2013
Botswana has made substantial progress towards malaria elimination across the country. This work assessed interventions and epidemiological characteristics of malaria in Botswana, during a period of decreasing transmission intensity. National passive malaria surveillance data for five years (2008-2012) were analysed. A district-level, random effects model with Poisson regression was used ...
Steele Joel S JS Psychology Department, Portland State University, 1721 SW Broadway, Portland, Oregon, 97201, USA, - - 2013
We present an idiographic approach to modeling dyadic interactions using differential equations. Using data representing daily affect ratings from romantic relationships, we examined several models conceptualizing different types of dyadic interactions. We fitted each model to each of the dyads and the resulting AICc values were used to classify the ...
Lee Peter N PN P N Lee Statistics and Computing Ltd, Sutton, Surrey, United Kingdom. Electronic address: - - 2013
We quantified the decline in COPD risk following quitting using the negative exponential model, as previously carried out for other smoking-related diseases. We identified 14 blocks of RRs (from 11 studies) comparing current smokers, former smokers (by time quit) and never smokers, some studies providing sex-specific blocks. Corresponding pseudo-numbers of ...
Scholte Ronaldo G C RG Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, P.O. Box, CH-4002 Basel, Switzerland; University of Basel, P.O. Box, CH-4003 Basel, Switzerland; Coordenação Geral de Hanseníase e Doenças em Eliminação, Secretaria de Vigilância em Saúde-MS, SCS Qd 4 Bloco A Ed. Principal 3° andar - CEP: 70304-000, Brasília DF, - - 2013
Schistosomiasis is one of the most common parasitic diseases in tropical and subtropical areas, including Brazil. A national control programme has been instigated in Brazil in the mid-1970s and proved successful in terms of morbidity control, as the number of cases with hepato-splenic involvement has been reduced significantly. To consolidate ...
Haney Joseph T JT Jr Toxicology Division,Austin,TX,United States. Electronic address: - - 2013
A unit risk factor (URF) was developed for hexavalent chromium (CrVI). The URF is based on excess lung cancer mortality in two key epidemiological studies of chromate production workers. The Crump et al. (2003) study concerns the Painesville, OH worker cohort, while Gibb et al. (2000) regards the Baltimore, MD ...
Oh Jung Hun JH Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA. Electronic address: - - 2014
The association analysis between single nucleotide polymorphisms (SNPs) and disease or endpoint in genome-wide association studies (GWAS) has been considered as a powerful strategy for investigating genetic susceptibility and for identifying significant biomarkers. The statistical analysis approaches with simulated data have been widely used to review experimental designs and performance ...
Wen Xiaoquan X Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, - - 2013
Motivated by examples from genetic association studies, this article considers the model selection problem in a general complex linear model system and in a Bayesian framework. We discuss formulating model selection problems and incorporating context-dependent a priori information through different levels of prior specifications. We also derive analytic Bayes factors ...
Rashidi H H Animal Breeding and Genomics Centre, Wageningen University, P.O. Box 338, 6700 AH, Wageningen, The - - 2013
Porcine reproductive and respiratory syndrome (PRRS) is a viral disease with negative impacts on reproduction of sows. Genetic selection to improve the response of sows to PRRS could be an approach to control the disease. Determining sow response to PRRS requires knowing pathogen burden and sow performance. In practice, though, ...
Cid Begoña B Departamento de Matemática Aplicada II, Universidade de Vigo, 36310 Vigo, Spain. Electronic address: - - 2013
The timing of harvesting is a key instrument in managing and exploiting biological populations and renewable resources. Yet, there is a little theory on harvest timing, and even less is known about the impact of different harvest times on the stability of population dynamics, even though this may drive population ...
Alkhasawneh Mutasem Sh MSh Imaging and Computational Intelligence (ICI) Group, School of Electrical & Electronic Engineering, Universiti Sains Malaysia, Engineering Campus, 14300 Nibong Tebal, Penang, - - 2013
Landslide is one of the natural disasters that occur in Malaysia. Topographic factors such as elevation, slope angle, slope aspect, general curvature, plan curvature, and profile curvature are considered as the main causes of landslides. In order to determine the dominant topographic factors in landslide mapping analysis, a study was ...
Alisauskas Ray T RT Environment Canada Saskatoon, Saskatchewan, - - 2014
Estimates of range-wide abundance, harvest, and harvest rate are fundamental for sound inferences about the role of exploitation in the dynamics of free-ranging wildlife populations, but reliability of existing survey methods for abundance estimation is rarely assessed using alternative approaches. North American mallard populations have been surveyed each spring since ...
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