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Corberán-Vallet Ana A 1Department of Statistics and Operations Research, University of Valencia, Burjassot, - - 2014
In this paper, we describe a Bayesian hierarchical Poisson model for the prospective analysis of data for infectious diseases. The proposed model consists of two components. The first component describes the behavior of disease during nonepidemic periods and the second component represents the increase in disease counts due to the ...
Kermany Amir R AR Department of Human Genetics, 920 E 58th Street, University of Chicago, Chicago, IL 60637, - - 2014
An estimated 10-30% of clinically recognized conceptions are aneuploid, leading to spontaneous miscarriages, IVF failures and, when viable, severe developmental disabilities. With the ongoing reduction in the cost of genotyping and DNA sequencing, the use of high density SNP markers for clinical diagnosis of aneuploidy and biomedical research into its ...
Murphy Adrianna A European Centre on Health of Societies in Transition (ECOHOST), Department of Health Services Research and Policy, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, - - 2014
The purpose of this study was to assess whether alcohol-related community characteristics act collectively to influence individual-level alcohol consumption in the former Soviet Union (fSU). Using multi-level data from nine countries in the fSU we conducted a factor analysis of seven alcohol-related community characteristics. The association between any latent factors ...
Commisso María S - - 2014
A finite element model of the temporomandibular joint (TMJ) and the human mandible was fabricated to study the effect of abnormal loading, such as awake and asleep bruxism, on the articular disc. A quasilinear viscoelastic model was used to simulate the behaviour of the disc. The viscoelastic nature of this ...
Yörük Barış K BK Department of Economics, University at Albany, SUNY, 1400 Washington Avenue, Albany, NY 12222, United States. Electronic address: - - 2014
Underage drinkers often use false identification to purchase alcohol or gain access into bars. In recent years, several states have introduced laws that provide incentives to retailers and bar owners who use electronic scanners to ensure that the customer is 21 years or older and uses a valid identification to ...
Gere Attila A Sensory Laboratory, Faculty of Food Science, Corvinus University of Budapest, H-1118, Budapest, Villányi út, 29-43, - - 2014
Traditional internal and external preference mapping methods are based on principal component analysis (PCA). However, parallel factor analysis (PARAFAC) and Tucker-3 methods could be a better choice. To evaluate the methods, preference maps of sweet corn varieties will be introduced. A preference map of eight sweet corn varieties was established ...
Verhulst Brad B Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine (VCU), Box 980126, Richmond, VA, 23298-0126, USA, - - 2014
Twin and family studies implicitly assume that the covariation between family members remains constant across differences in age between the members of the family. However, age-specificity in gene expression for shared environmental factors could generate higher correlations between family members who are more similar in age. Cohort effects (cohort × genotype or ...
Holmes Philip P Department of Mechanical and Aerospace Engineering, Princeton University; Program in Applied and Computational Mathematics, Princeton University; Princeton Neuroscience Institute, Princeton - - 2014
We review how leaky competing accumulators (LCAs) can be used to model decision making in two-alternative, forced-choice tasks, and we show how they reduce to drift diffusion (DD) processes in special cases. As continuum limits of the sequential probability ratio test, DD processes are optimal in producing decisions of specified ...
Schwabe Inga I Department of Research Methodology, Measurement, and Data Analysis, University of Twente, Drienerlolaan 5, 7522 NB,  Enschede, The Netherlands, - - 2014
Considerable effort has been devoted to establish genotype by environment interaction (G [Formula: see text] E) in case of unmeasured genetic and environmental influences. Although it has been outlined by various authors that the appearance of G [Formula: see text] E can be dependent on properties of the given measurement ...
Steiling W W Henkel AG & Co KGaA, Henkelstr. 67, D-40191 Düsseldorf, Germany. Electronic address: - - 2014
In recent years, the official regulation of chemicals and chemical products has been intensified. Explicitly for spray products enhanced requirements to assess the consumers'/professionals' exposure to such product type have been introduced. In this regard the Aerosol-Dispensers-Directive (75/324/EEC) with obligation for marketing aerosol dispensers, and the Cosmetic-Products-Regulation (1223/2009/EC) which obliges ...
Shaw William S WS Liberty Mutual Research Institute for Safety, 71 Frankland Road, Hopkinton, MA, 01748, USA, - - 2014
Introduction An employer offer of temporary job modification is a key strategy for facilitating return-to-work for musculoskeletal conditions, but there are no validated scales to assess the level of support for temporary job modifications across a range of job types and organizations. Objective To pilot test a new 21-item self-report ...
Xia Yang Y Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, - - 2014
Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) was measured in all participants aged 6 years and older from the Centers for Disease Control and Prevention's National Health and Nutrition Examination Survey 2007-2008. The suitability of using creatinine or specific gravity for urinary NNAL correction in exposure assessment is examined in this study. Effects ...
Kapo Katherine E KE Waterborne Environmental, Inc., Leesburg, Virginia, - - 2014
Eco-epidemiological studies utilizing existing monitoring program data provide a cost-effective means to bridge the gap between ecological and chemical status of watersheds and to develop hypotheses of stressor attribution that can influence the design of higher-tier assessments and subsequent management. The present study describes the process of combining existing data ...
Schwarz Norbert G NG Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht street 74, D-20359 Hamburg, Germany. Electronic address: - - 2014
Madagascar is an endemic area for schistosomiasis, but recent prevalence data are scarce. We investigated stool samples of 410 children aged 4-18 years from a combined primary and secondary school in a Madagascan highland village near Ambositra in order to assess the prevalence of Schistosoma mansoni using microscopy and real-time ...
Fischer Jesse R JR Department of Natural Resource Ecology and Management, Iowa State University, 339 Science II, Ames, IA, 50010, USA, - - 2014
Characterizing fish assemblages in lentic ecosystems is difficult, and multiple sampling methods are almost always necessary to gain reliable estimates of indices such as species richness. However, most research focused on lentic fish sampling methodology has targeted recreationally important species, and little to no information is available regarding the influence ...
Fernández Israel I Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040-Madrid, Spain. - - 2014
The recently introduced activation strain model (ASM) has allowed us to gain more insight into the intimacies of different fundamental processes in chemistry. In combination with the energy decomposition analysis (EDA) method, we have nowadays a very useful tool to quantitatively understand the physical factors that govern the activation barriers ...
Searle John J Road Accident Analysis, United - - 2014
A dilution model is widely used to link blood alcohol concentration and the quantity of alcohol consumed. Whilst some authors use the total body water formulation of that model, others use the Widmark Factor formulation. A paper by Forrest gave a table of example values of the Widmark Factor and ...
Dimitrov B D BD Academic Unit of Primary Care & Population Sciences, Faculty of Medicine, University of Southampton, Southampton, - - 2014
SUMMARY Multicomponent cyclicity in influenza (flu) incidence had been observed in various countries (e.g. periods T = 1, 2-3, 5-6, 8·0, 10·6-11·3, 13, 18-19 years) and its close similarity with cycles in natural environmental phenomena as meteorological factors and heliogeophysical activity (HGA) suggested. This report aimed at verifying previous results on cyclic ...
Crouch Simon S Epidemiology & Cancer Statistics Group, Department of Health Sciences, University of York, YO10 5DD, UK. Electronic address: - - 2014
We present a new method for determining prevalence estimates together with estimates of their precision, from incidence and survival data using Monte-Carlo simulation techniques. The algorithm also provides for the incidence process to be marked with the values of subject level covariates, facilitating calculation of the distribution of these variables ...
Kochunov Peter P Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: - - 2014
Combining datasets across independent studies can boost statistical power by increasing the numbers of observations and can achieve more accurate estimates of effect sizes. This is especially important for genetic studies where a large number of observations are required to obtain sufficient power to detect and replicate genetic effects. There ...
Onogi A A Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, - - 2014
The implementation of genomic selection for Japanese Black cattle known for rich marbling of their meat, is now being explored. Although multiple-step methods are often adopted for dairy cattle, they present shortcomings such as bias and loss of information in addition to operational complexity. These can be avoided using single-step ...
Siddique Juned J Department of Preventive Medicine, Northwestern University, Chicago, IL, - - 2014
The true missing data mechanism is never known in practice. We present a method for generating multiple imputations for binary variables, which formally incorporates missing data mechanism uncertainty. Imputations are generated from a distribution of imputation models rather than a single model, with the distribution reflecting subjective notions of missing ...
Gravel Simon S McGill - - 2014
Successful sequencing experiments require judicious sample selection. However, this selection must often be performed on the basis of limited preliminary data. Predicting the statistical properties of the final sample based on preliminary data can be challenging, because numerous uncertain model assumptions may be involved. Here, we ask whether we can ...
Helpman Liat L a Psychology Department and Gonda Brain Research Center , Bar-Ilan - - 2014
The applicability of diagnostic criteria of Posttraumatic Stress Disorder to the pediatric population has been a focus of much debate (e.g., Carrion, Weems, Ray, & Reiss, 2002 ), informing changes in the Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5). The current study examined the factor structure of ...
Li Xin-Xu - - 2014
The report of the fifth national tuberculosis (TB) epidemiological survey in P. R. China, 2010, roughly showed that pulmonary TB (PTB) prevalence was higher in western China than in central and eastern China. However, accurately estimating the continuous spatial variations of PTB prevalence and clearly understanding factors impacting on spatial ...
Taylor Aimee R - - 2014
Reliable measures of anti-malarial resistance are crucial for malaria control. Resistance is typically a complex trait: multiple mutations in a single parasite (a haplotype or genotype) are necessary for elaboration of the resistant phenotype. The frequency of a genetic motif (proportion of parasite clones in the parasite population that carry ...
Shringarpure Suyash S Stanford - - 2014
Population stratification is an important task in genetic analyses. It provides information about the ancestry of individuals and can be an important confounder in genome-wide association studies. Public genotyping projects have made a large number of datasets available for study. However, practical constraints dictate that of a geographical/ethnic population, only ...
Wang Chaolong C 1] Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA. [2] Department of Biostatistics, Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA. - - 2014
Estimating individual ancestry is important in genetic association studies where population structure leads to false positive signals, although assigning ancestry remains challenging with targeted sequence data. We propose a new method for the accurate estimation of individual genetic ancestry, based on direct analysis of off-target sequence reads, and implement our ...
Akanno E C EC Department of Animal & Poultry Science, Centre for Genetic Improvement of Livestock, University of Guelph, Guelph, ON, - - 2014
Genetic improvement of pigs in tropical developing countries has focused on imported exotic populations which have been subjected to intensive selection with attendant high population-wide linkage disequilibrium (LD). Presently, indigenous pig population with limited selection and low LD are being considered for improvement. Given that the infrastructure for genetic improvement ...
Yang Shengping - - 2014
Accurate genotype calling is a pre-requisite of a successful Genome-Wide Association Study (GWAS). Although most genotyping algorithms can achieve an accuracy rate greater than 99% for genotyping DNA samples without copy number alterations (CNAs), almost all of these algorithms are not designed for genotyping tumor samples that are known to ...
Goedhart Paul W PW Biometris, Plant Research International, Wageningen University and Research Centre P.O. Box 16, 6700 AA, Wageningen, The - - 2014
Genetic modification of plants may result in unintended effects causing potentially adverse effects on the environment. A comparative safety assessment is therefore required by authorities, such as the European Food Safety Authority, in which the genetically modified plant is compared with its conventional counterpart. Part of the environmental risk assessment ...
Chen Chun C School of Mechanical Engineering, Purdue University, 47907, West Lafayette, IN, - - 2014
Covering a cough can be useful in reducing the transmission of airborne infectious diseases. However, no simple method is available in the literature for predicting the exhaled airflow from a cough with the mouth covered. This investigation used smoke to visualize the airflow exhaled by 16 human subjects. Their mouths ...
Chevillotte G G Laboratoire d'Evaluation du Risque Chimique pour le Consommateur (LERCCo), Université Européenne de Bretagne - Université de Bretagne Occidentale (UEB-UBO), UFR Sciences et Techniques, 6 Av. Victor Le Gorgeu, CS93837, 29238 Brest Cedex 3, - - 2014
In a risk assessment of cosmetic products, it is necessary to know both qualitative and quantitative compositions. Currently, European Regulation No 1223/2009 requires the industries to provide ingredient lists for finished cosmetic products but not their concentrations. Ingredient concentrations are available in few bibliographic references but in an incomplete and ...
Boucquemont Julie - - 2014
Chronic kidney disease (CKD) is a progressive and usually irreversible disease. Different types of outcomes are of interest in the course of CKD such as time-to-dialysis, transplantation or decline of the glomerular filtration rate (GFR). Statistical analyses aiming at investigating the association between these outcomes and risk factors raise a ...
Zendegui Elaina A EA Rutgers, The State University of New Jersey, Graduate School of Applied and Professional Psychology, 41 Gordon Road, Suite C, Piscataway, NJ 08854, USA. Electronic address: - - 2014
Cognitive behavioral guided self-help (CBTgsh) is an evidence-based, brief, and cost-effective treatment for eating disorders characterized by recurrent binge eating. However, more research is needed to improve patient outcomes and clarify treatment components most associated with symptom change. A main component of CBTgsh is establishing a regular pattern of eating ...
Waller Alison S AS Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, - - 2014
Bacteriophages have key roles in microbial communities, to a large extent shaping the taxonomic and functional composition of the microbiome, but data on the connections between phage diversity and the composition of communities are scarce. Using taxon-specific marker genes, we identified and monitored 20 viral taxa in 252 human gut ...
Herrera Paz Edwin Francisco EF Universidad Católica de Honduras, San Pedro, Sula, - - 2014
In this work, we investigated surname distribution in 4,348,021 Honduran electors with the aim of detecting population structure through the study of isonymy in three administrative levels: the whole nation, the 18 departments, and the 298 municipalities. For each administrative level, we studied the surname effective number, α, the total ...
Gertz Michael M Centre for Applied Pharmacokinetic Research Manchester Pharmacy School, The University of Manchester, Oxford Road, M13 9PT, Manchester, - - 2014
To investigate the effect of OATP1B1 genotype as a covariate on repaglinide pharmacokinetics and drug-drug interaction (DDIs) risk using a reduced physiologically-based pharmacokinetic (PBPK) model. Twenty nine mean plasma concentration-time profiles for SLCO1B1 c.521T>C were used to estimate hepatic uptake clearance (CLuptake) in different genotype groups applying a population approach ...
Kribs-Zaleta Christopher M CM Department of Mathematics, University of Texas at Arlington, Box 19408, Arlington, TX 76019-0408 USA. Electronic address: - - 2014
The notion of evolutionary trade-off (one attribute increasing at the expense of another) is central to the evolution of traits, well-studied especially in life-history theory, where a framework first developed by Levins illustrates how internal (genetics) and external (fitness landscapes) forces interact to shape an organism's ongoing adaptation. This manuscript ...
Jiménez-Gómez José M JM INRA - Institut National de la Recherche Agronomique, UMR 1318, Institut Jean-Pierre Bourgin, Versailles, France; Max Planck Institute for Plant Breeding Research, Department of Plant Breeding and Genetics, Carl-von-Linné-Weg 10, 50829 Cologne, Germany. Electronic address: - - 2014
We are in the age of data-driven biology. Not even a decade after the invention of high-throughput sequencing technologies, there are methods that accurately monitor DNA polymorphisms, transcription profiles, methylation states, transcription factor binding sites, chromatin compactness, nucleosome positions, dynamic histone marks, and so on. We are starting to generate ...
Filgueiras A A University of Western Ontario (UWO), Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio), Brazil. Electronic address: - - 2014
Several studies have attempted to understand the dimensions of psychiatric symptoms in manic episodes, but only a few have been able to model the latent structure of mania in bipolar disorder patients using confirmatory factor analysis. The objective of the present study was to search for the best model of ...
Adams Mark M Evolutionary Biology Unit, South Australian Museum, North Terrace SA 5000, - - 2014
Several recent estimates of global biodiversity have concluded that the total number of species on Earth lies near the lower end of the wide range touted in previous decades. However, none of these recent estimates formally explore the real 'elephant in the room', namely, what proportion of species are taxonomically ...
Ricotta Emily E - - 2014
In places where malaria transmission is unstable or is transmitted under hypoendemic conditions, there are periods where limited foci of cases still occur and people become infected. These residual "hot spots" are likely reservoirs of the parasite population and so are fundamental to the seasonal spread and decline of malaria. ...
Gavina Maica Krizna A MK Institute of Mathematical Sciences and Physics, University of the Philippines Los Baños, Laguna, 4031, - - 2014
Farmers frequently decide where to locate the colonies of their domesticated eusocial bees, especially given the following mutually exclusive scenarios: (i) there are limited nectar and pollen sources within the vicinity of the apiary that cause competition among foragers; and (ii) there are fewer pollinators compared to the number of ...
Fang Cheng-Ran CR School of Civil Engineering and Architecture, Zhejiang University of Science and Technology, Hangzhou, 310023, China, - - 2014
Sorption is a fundamental process controlling the transformation, fate, degradation, and biological activity of hydrophobic organic contaminants in the environment. We investigated the kinetics, isotherms, and potential mechanisms for the sorption of two phthalic acid esters (PAEs), dibutyl phthalate (DBP) and dioctyl phthalate (DOP), on aged refuse. A two-compartment first-order ...
Brook Ah A School of Dentistry, The University of Adelaide, South Australia, Australia; Institute of Dentistry, Queen Mary University of London, United - - 2014
Complex systems are present in such diverse areas as social systems, economies, ecosystems and biology and, therefore, are highly relevant to dental research, education and practice. A Complex Adaptive System in biological development is a dynamic process in which, from interacting components at a lower level, higher level phenomena and ...
Sjölander A A Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, - - 2014
A common goal of epidemiologic research is to study how two exposures interact in causing a binary outcome. Causal interaction is defined as the presence of subjects for which the causal effect of one exposure depends on the level of the other exposure. For binary exposures, it has previously been ...
Leaché Adam D AD Department of Biology, University of Washington, Seattle, WA 98195, - - 2014
The multispecies coalescent has provided important progress for evolutionary inferences, including increasing the statistical rigor and objectivity of comparisons among competing species delimitation models. However, Bayesian species delimitation methods typically require brute force integration over gene trees via Markov chain Monte Carlo (MCMC), which introduces a large computation burden and ...
Chen Senlin S Department of Kinesiology, Iowa State University, United States. Electronic address: - - 2014
Physical inactivity needs to be strategically addressed from and throughout childhood and adolescence. The youth physical activity promotion model provides a comprehensive framework for understanding and promoting physical activity in youth. This study examined psychometric characteristics of the children's attraction to physical activity scale and the perceived physical competence scale, ...
Bornbaum Catherine C - - 2014
PURPOSE The construct validity of the Voice-Related Quality of Life (V-RQOL; Hogikyan & Sethuraman, 1999) measure was evaluated in a sample of 109 individuals who have undergone total laryngectomy. METHOD A principal components factor analysis was performed on participant responses to the 10-question V-RQOL measure. RESULTS Factor analysis of the ...
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