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Finucane Mariel M MM The J. David Gladstone Institutes, San Francisco, California, United States of - - 2014
Obesity is an important and intractable public health problem. In addition to the well-known risk factors of behavior, diet, and genetics, gut microbial communities were recently identified as another possible source of risk and a potential therapeutic target. However, human and animal-model studies have yielded conflicting results about the precise ...
Bansal Vikas V Department of Cardiovascular Genetics, Experimental and Clinical Research Center, Charité - Universitätsmedizin Berlin and Max Delbrück Center (MDC) for Molecular Medicine, Berlin, Germany ; Department of Mathematics and Computer Science, Free University of Berlin, Berlin, - - 2014
Copy number variations (CNVs) are one of the main sources of variability in the human genome. Many CNVs are associated with various diseases including cardiovascular disease. In addition to hybridization-based methods, next-generation sequencing (NGS) technologies are increasingly used for CNV discovery. However, respective computational methods applicable to NGS data are ...
Chan Matthew H T MH School of Mathematics and Statistics, University of Sydney, Sydney, New South Wales, - - 2014
There have been numerous empirical studies on the fitness consequences of behavioural syndromes in various animal taxa; however, the ecological and evolutionary implications on a population level are still poorly understood. To better understand these implications, we develop a non-linear age-structured mathematical model to qualitatively examine the evolutionary consequences of ...
Tang Fenyang F Jiangsu Province Center for Disease Control and Prevention, Nanjing, Jiangsu, - - 2014
This study aimed to describe the spatial and temporal trends of Shigella incidence rates in Jiangsu Province, People's Republic of China. It also intended to explore complex risk modes facilitating Shigella transmission. County-level incidence rates were obtained for analysis using geographic information system (GIS) tools. Trend surface and incidence maps ...
Valverde-Albacete Francisco J FJ Departamento de Lenguajes y Sistemas Informáticos, Universidad Nacional de Educación a Distancia, Madrid, - - 2014
THE MOST WIDELY SPREAD MEASURE OF PERFORMANCE, ACCURACY, SUFFERS FROM A PARADOX: predictive models with a given level of accuracy may have greater predictive power than models with higher accuracy. Despite optimizing classification error rate, high accuracy models may fail to capture crucial information transfer in the classification task. We ...
Nguyen Thuan T Department of Public Health and Preventive Medicine, Oregon Health and Science University, Portland, OR 97239, - - 2014
Model search strategies play an important role in finding simultaneous susceptibility genes that are associated with a trait. More particularly, model selection via the information criteria, such as the BIC with modifications, have received considerable attention in quantitative trait loci (QTL) mapping. However, such modifications often depend upon several factors, ...
Farzadfar Farshad F Non-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran, Endocrinology and Metabolism Research center, Endocrinology and Metabolism Research Institute, Tehran, Iran. - - 2014
Iran has witnessed a substantial demographic and health transition, especially during the past 2 decades, which necessitates updated evidence-based policies at national and indeed at subnational scale. The National and Subnational Burden of Diseases, Injuries, and Risk Factors (NASBOD) Study aims to provide the required evidence based on updated data ...
Kasaeian Amir A Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran, Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medecine, Tehran, Iran. mohamadk@tums.ac.ir, - - 2014
Statistical modeling and developing new methods for estimating burden of diseases, injuries and risk factors is a fundamental concern in studying the country health situation for better health management and policy making. Bayesian autoregressive multilevel model is a strong method for this kind of study though in complex situations it ...
Parsaeian Mahboubeh M Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran, Non-Communicable Disease Research Center, Endocrinology and Metabolism Population Science Research Institute, Tehran University of Medical Sciences, Tehran, Iran. mohamadk@ tums.ac.ir, - - 2014
Identifying the burden of disease and its inequality between geographical regions is an important issue to study health priorities. Estimating burden of diseases using statistical models is inevitable especially in the context of rare data availability. To this purpose, the spatio-temporal model can provide a statistically sound approach for explaining ...
Eastwood John G JG South Western Sydney Local Health District, Locked Mail Bag 7279, Liverpool BC 1871, Sydney, NSW Australia ; School of Public Health and Community Medicine, The University of New South Wales, Sydney, NSW 2052 Australia ; School of Women's and Children's Health, The University of New South Wales, Sydney, NSW 2052 Australia ; School of Public Health, University of Sydney, Sydney, NSW 2006 Australia ; School of Public Health, Griffith University, Gold Coast, QLD 4222 - - 2014
A recent criticism of social epidemiological studies, and multi-level studies in particular has been a paucity of theory. We will present here the protocol for a study that aims to build a theory of the social epidemiology of maternal depression. We use a critical realist approach which is trans-disciplinary, encompassing ...
Weitkamp Katharina K Department of Child and Adolescent Psychiatry, Psychotherapy, and Psychosomatics, University Medical Centre Hamburg-Eppendorf, Hamburg, - - 2014
During the past several years, there has been a growing interest in the negative effects that providing therapy may have on therapists. Of special interest is a phenomenon called secondary traumatization, which can arise while working with traumatized clients. To develop a simple screening tool for secondary traumatization, a quantitative ...
Zhao Qing Q 1] Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China [2] Stockbridge School of Agriculture, University of Massachusetts, Amherst, MA 01003, - - 2014
Adsorption of organic compounds on carbon nanotubes (CNTs), governed by interactions between molecules and CNTs surfaces, is critical for their fate, transport, bioavailability and toxicity in the environment. Here, we report a promising concentration-dependent polyparameter linear free energy relationships (pp-LFERs) model to describe the compound-CNTs interactions and to predict sorption ...
Kolk Martin M Demography Unit, Department of Sociology, Stockholm University, , 10691 Stockholm, Sweden, Center for the Study of Cultural Evolution, Stockholm University, , 10691 Stockholm, Sweden, Department of Zoology, Stockholm University, , 10691 Stockholm, - - 2014
Correlations in family size across generations could have a major influence on human population size in the future. Empirical studies have shown that the associations between the fertility of parents and the fertility of children are substantial and growing over time. Despite their potential long-term consequences, intergenerational fertility correlations have ...
Grassi-Oliveira Rodrigo R Centre of Studies and Research in Traumatic Stress, Post-Graduate Program in Psychology, Pontifical Catholic University of the Rio Grande do Sul (PUCRS), Porto Alegre, RS, - - 2014
The Childhood Trauma Questionnaire (CTQ) is internationally accepted as a key tool for the assessment of childhood abuse and neglect experiences. However, there are relative few psychometric studies available and some authors have proposed two different factor solutions. We examined the dimensional structure and internal consistency of the Brazilian version ...
He Dongxiao D College of Computer Science and Technology, Jilin University, Changchun, China ; Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education, Jilin University, Changchun, - - 2014
Discovery of communities in complex networks is a fundamental data analysis problem with applications in various domains. While most of the existing approaches have focused on discovering communities of nodes, recent studies have shown the advantages and uses of link community discovery in networks. Generative models provide a promising class ...
Santin-Janin Hugues H Office National de la Chasse et de la Faune Sauvage, Direction des Études et de la Recherche, Le Perray-en-Yvelines, France ; Université de Lyon, Lyon, Université Lyon 1, CNRS, UMR 5558, Laboratoire de Biométrie et Biologie Evolutive, Villeurbanne, - - 2014
Data collected to inform time variations in natural population size are tainted by sampling error. Ignoring sampling error in population dynamics models induces bias in parameter estimators, e.g., density-dependence. In particular, when sampling errors are independent among populations, the classical estimator of the synchrony strength (zero-lag correlation) is biased downward. ...
Levy Jonathan I JI Department of Environmental Health, Boston University School of Public Health, Boston, Massachusetts, United States of - - 2014
Evaluating environmental health risks in communities requires models characterizing geographic and demographic patterns of exposure to multiple stressors. These exposure models can be constructed from multivariable regression analyses using individual-level predictors (microdata), but these microdata are not typically available with sufficient geographic resolution for community risk analyses given privacy concerns. ...
Nguyen Minh Thac MT Department of Economics, University of Illinois at Chicago, Chicago, Illinois, United States of - - 2014
Illicit trade carries the potential to magnify existing tobacco-related health care costs through increased availability of untaxed and inexpensive cigarettes. What is known with respect to the magnitude of illicit trade for Vietnam is produced primarily by the industry, and methodologies are typically opaque. Independent assessment of the illicit cigarette ...
Amori Giovanni G CNR - Institute of Ecosystem Studies, viale dell'Università 32, I-00185 Rome, - - 2014
Recent molecular evidence suggests that Sciurus vulgaris populations from Calabria (southern Italy) are distinct from those occurring in northern and central Italy. Here, we re-analyzed using multivariate and univariate techniques an historical dataset provided by Cavazza (1913), who documented measurements for the now extinct squirrel population from Campania. Both univariate ...
Jaén-Moreno María J MJ UGC Salud Mental. Hospital Universitario Reina Sofía. - - 2014
Introduction. Interest in the existence of anomalous perceptions in the general population has increased greatly over recent years. Because of this, it has been possible to extend the knowledge regarding the theory of psychosis as a dimensional model. This study has aimed to validate the Spanish version of the Cardiff ...
Manzano-Piedras Esperanza E Departamento de Ecología Integrativa, Estación Biológica de Doñana (EBD), Consejo Superior de Investigaciones Científicas (CSIC), Sevilla, - - 2014
The role that different life-history traits may have in the process of adaptation caused by divergent selection can be assessed by using extensive collections of geographically-explicit populations. This is because adaptive phenotypic variation shifts gradually across space as a result of the geographic patterns of variation in environmental selective pressures. ...
Su Meng - - 2014
Some aspects of the neighborhood built environment may influence residents' physical activity, which in turn, affects their health. This study aimed to develop an urban built environment evaluation tool and conduct necessary reliability and validity tests. A 41-item urban built environment scan tool was developed to objectively assess the neighborhood ...
Gauvin Laetitia L Data Science Laboratory, ISI Foundation, Torino, - - 2014
The increasing availability of temporal network data is calling for more research on extracting and characterizing mesoscopic structures in temporal networks and on relating such structure to specific functions or properties of the system. An outstanding challenge is the extension of the results achieved for static networks to time-varying networks, ...
Andreo Veronica V Instituto de Altos Estudios Espaciales "Mario Gulich", Centro Espacial Teófilo Tabanera, CONAE, Ruta Provincial C45, Km 8, Falda del Carmen, Córdoba 5187, Argentina. - - 2014
We use a Species Distribution Modeling (SDM) approach along with Geographic Information Systems (GIS) techniques to examine the potential distribution of hantavirus pulmonary syndrome (HPS) caused by Andes virus (ANDV) in southern Argentina and, more precisely, define and estimate the area with the highest infection probability for humans, through the ...
Harris Morgan R MR Appalachian State University Biology Department, Boone, North Carolina, United States of - - 2014
Territorial aggression influences fitness and, in monogamous pairs, the behavior of both individuals could impact reproductive success. Moreover, territorial aggression is particularly important in the context of interspecific competition. Tree swallows and eastern bluebirds are highly aggressive, secondary cavity-nesting birds that compete for limited nesting sites. We studied eastern bluebirds ...
Sunde Peter P Department of Bioscience, Aarhus University, Rønde, - - 2014
Despite the dynamic nature of habitat selection, temporal variation as arising from factors such as weather are rarely quantified in species-habitat relationships. We analysed habitat use and selection (use/availability) of foraging, radio-tagged little owls (Athene noctua), a nocturnal, year-round resident generalist predator, to see how this varied as a function ...
Tian Li-Ping LP School of Information, Beijing Wuzi University, No. 1 Fuhe Street, Tongzhou District, Beijing 101149, - - 2014
Microarray technology has produced a huge body of time-course gene expression data and will continue to produce more. Such gene expression data has been proved useful in genomic disease diagnosis and drug design. The challenge is how to uncover useful information from such data by proper analysis methods such as ...
Limam Mansar Selma S Information Systems Program, Carnegie Mellon University, Doha, - - 2014
Obesity has become a worldwide epidemic. Qatar, a rapidly developing country in the Middle East, has seen a sharp increase in the prevalence of obesity. The increase can be attributed to several reasons, including sedentary lifestyles imposed by a harsh climate and the introduction of Western fast food. Mobile technologies ...
Bachir Bouamoud B SIME Lab, MIS Team, ENSIAS, University of Mohammed V SOUISSI, Madinat Al Irfane, BP 713, Agdal, Rabat, - - 2014
The radio link between a pair of wireless nodes is affected by a set of random factors such as transmission range, node mobility, and environment conditions. The properties of such radio links are continually experienced when nodes status balances between being reachable and being unreachable; thereby on completion of each ...
Bandeiras Cátia C Instituto Gulbenkian de Ciência, Oeiras, - - 2014
After remarkable success of vector control campaigns worldwide, concerns about loss of immunity against Plasmodium falciparum due to lack of exposure to the parasite are relevant since an increase of severe cases in less immune individuals is expected. We present a mathematical model to investigate the impact of reducing exposure ...
Wong Un-Hong UH 0000-0002-4954-7846 Space Science Institute, Macau University of Science and Technology, Macao, - - 2014
In this paper, we model the reflectance of the lunar regolith by a new method combining Monte Carlo ray tracing and Hapke's model. The existing modeling methods exploit either a radiative transfer model or a geometric optical model. However, the measured data from an Interference Imaging spectrometer (IIM) on an ...
Abdul Khalil Khalilah K Department of Biomolecular Sciences, Faculty of Applied Sciences, Universiti Teknologi MARA, Sec. 2, 40150 Shah Alam, Selangor, - - 2014
This study was undertaken to optimize skim milk and yeast extract concentration as a cultivation medium for optimal Bifidobacteria pseudocatenulatum G4 (G4) biomass and β -galactosidase production as well as lactose and free amino nitrogen (FAN) balance after cultivation period. Optimization process in this study involved four steps: screening for ...
Carlson Jean M JM Department of Physics, University of California Santa Barbara, Santa Barbara, California, United States of - - 2014
Identifying and quantifying factors influencing human decision making remains an outstanding challenge, impacting the performance and predictability of social and technological systems. In many cases, system failures are traced to human factors including congestion, overload, miscommunication, and delays. Here we report results of a behavioral network science experiment, targeting decision ...
Ranjbar Reza R Molecular Biology Research Center, Baqiyatallah University of Medical Sciences, Tehran, - - 2014
Microbial typing is often employed to determine the source and routes of infections, confirm or rule out outbreaks, trace cross-transmission of healthcare-associated pathogens, recognize virulent strains and evaluate the effectiveness of control measures. Conventional microbial typing methods have occasionally been useful in describing the epidemiology of infectious diseases. However, these ...
Ferraro Angus J AJ Department of Meteorology, University of Reading, Reading, United - - 2014
Geoengineering by stratospheric aerosol injection has been proposed as a policy response to warming from human emissions of greenhouse gases, but it may produce unequal regional impacts. We present a simple, intuitive risk-based framework for classifying these impacts according to whether geoengineering increases or decreases the risk of substantial climate ...
Jalan Sarika S Complex Systems Lab, Indian Institute of Technology Indore, Indore, Madhya Pradesh, - - 2014
An understanding of how individuals shape and impact the evolution of society is vastly limited due to the unavailability of large-scale reliable datasets that can simultaneously capture information regarding individual movements and social interactions. We believe that the popular Indian film industry, "Bollywood", can provide a social network apt for ...
Wang Zhensheng Z School of Resource and Environmental Science, Wuhan University, 129 Luoyu Road, Wuhan 430079, China. - - 2014
In China, awareness about hypertension, the treatment rate and the control rate are low compared to developed countries, even though China's aging population has grown, especially in those areas with a high degree of urbanization. However, limited epidemiological studies have attempted to describe the spatial variation of the geo-referenced data ...
Nettling Martin - - 2014
New technologies for analyzing biological samples, like next generation sequencing, are producing a growing amount of data together with quality scores. Moreover, software tools (e.g., for mapping sequence reads), calculating transcription factor binding probabilities, estimating epigenetic modification enriched regions or determining single nucleotide polymorphism increase this amount of position-specific DNA-related ...
Echeverry-Galvis Maria Angela MA Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America ; Departamento de Ecologia y Territorio, Pontificia Universidad Javeriana, Bogotá - - 2014
Group living is a life history strategy employed by many organisms. This strategy is often difficult to study because the exact boundaries of a group can be unclear. Weaverbirds present an ideal model for the study of group living, because their colonies occupy a space with discrete boundaries: a single ...
Le Ngoc - - 2014
Histone proteins are subject to various posttranslational modifications (PTMs). Elucidating their functional relationships is crucial toward understanding many biological processes. Bayesian network (BN)-based approaches have shown the advantage of revealing causal relationships, rather than simple cooccurrences, of PTMs. Previous works employing BNs to infer causal relationships of PTMs require that ...
Hua Jianping J Center for Bioinformatics and Genomic Systems Engineering, Texas A&M University, College Station, TX, - - 2014
Gene set enrichment analysis (GSA) methods have been widely adopted by biological labs to analyze data and generate hypotheses for validation. Most of the existing comparison studies focus on whether the existing GSA methods can produce accurate P-values; however, practitioners are often more concerned with the correct gene-set ranking generated ...
Lu Meng - - 2014
In order to have a better understanding of unexplained heritability for complex diseases in conventional Genome-Wide Association Studies (GWAS), aggregated association analyses based on predefined functional regions, such as genes and pathways, become popular recently as they enable evaluating joint effect of multiple Single-Nucleotide Polymorphisms (SNPs), which helps increase the ...
Martínez Víctor - - 2014
Prioritization methods have become an useful tool for mining large amounts of data to suggest promising hypotheses in early research stages. Particularly, network-based prioritization tools use a network representation for the interactions between different biological entities to identify novel indirect relationships. However, current network-based prioritization tools are strongly tailored to ...
Shimizu Takahiro T a Akita University , - - 2014
Abstract The author developed a new scale aimed at measuring beliefs about "hypnotic states" and investigated the influence of such beliefs and attitudes on hypnotic responses in a large sample of Japanese undergraduate students. Exploratory factor analysis of this new questionnaire examining beliefs about hypnotic states yielded four factors: Dissociative ...
Wang Jiancheng J Seed Science Center, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310058, China ; Shandong Crop Germplasm Center, Shandong Academy of Agricultural Sciences, Ji'nan 250100, - - 2014
Core collection is an ideal resource for genome-wide association studies (GWAS). A subcore collection is a subset of a core collection. A strategy was proposed for finding the optimal sampling percentage on plant subcore collection based on Monte Carlo simulation. A cotton germplasm group of 168 accessions with 20 quantitative ...
Jang Jae-Yeon JY Department of Preventive Medicine and Public Health, Ajou University School of Medicine, Suwon, - - 2014
A set of exposure factors that reflects the characteristics of individual behavior capable of influencing exposure is essential for risk and exposure assessment. In 2007, the Korean Exposure Factors Handbook was, therefore, issued, driven by the need to develop reliable exposure factors representing the Korean population. The purpose of this ...
Ditkovich Y Y Hybrid Energy Sources Laboratory, Department of Electrical Engineering and Electronics, Ariel University Center of Samaria, 40700 Ariel, - - 2014
Three approaches to calculating capacity factor of fixed speed wind turbines are reviewed and compared using a case study. The first "quasiexact" approach utilizes discrete wind raw data (in the histogram form) and manufacturer-provided turbine power curve (also in discrete form) to numerically calculate the capacity factor. On the other ...
Eliazar Iddo I II School of Chemistry, Raymond & Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, - - 2014
This paper presents a panoramic macroscopic outlook of rank distributions. We establish a general framework for the analysis of rank distributions, which classifies them into five macroscopic "socioeconomic" states: monarchy, oligarchy-feudalism, criticality, socialism-capitalism, and communism. Oligarchy-feudalism is shown to be characterized by discrete macroscopic rank distributions, and socialism-capitalism is shown ...
Jiang Yongshuai Y College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, - - 2014
Traditional permutation (TradPerm) tests are usually considered the gold standard for multiple testing corrections. However, they can be difficult to complete for the meta-analyses of genetic association studies based on multiple single nucleotide polymorphism loci as they depend on individual-level genotype and phenotype data to perform random shuffles, which are ...
Staunton Kyran M KM Centre for Tropical Biodiversity & Climate Change and School of Marine and Tropical Biology, James Cook University, Townsville, Queensland, - - 2014
With the impending threat of climate change, greater understanding of patterns of species distributions and richness and the environmental factors driving them are required for effective conservation efforts. Species distribution models enable us to not only estimate geographic extents of species and subsequent patterns of species richness, but also generate ...
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