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Engbers Ralf R Institute for Computational and Applied Mathematics, Westfälische Wilhelms-Universität (WWU) Münster, Einsteinstrasse 62, Münster 48149, Germany - - 2014
The identification of production functions from data is an important task in the modelling of economic growth. In this paper, we consider a non-parametric approach to this identification problem in the context of the spatial Solow model which allows for rather general production functions, in particular convex-concave ones that have ...
Albi G G Department of Mathematics and Computer Science, University of Ferrara, via Machiavelli 35, Ferrara 44121, - - 2014
The study of formations and dynamics of opinions leading to the so-called opinion consensus is one of the most important areas in mathematical modelling of social sciences. Following the Boltzmann-type control approach recently introduced by the first two authors, we consider a group of opinion leaders who modify their strategy ...
Beck L L CEA, DEN, Service de Recherches de Métallurgie Physique, Laboratoire JANNUS, 91191 Gif-sur-Yvette, France; C2RMF - UMR171 CNRS, Centre de Recherche et de Restauration des Musées de France, Palais du Louvre, Porte des Lions, 14 quai François Mitterrand, 75001 Paris, France. Electronic address: - - 2014
Study of prehistoric art is playing a major role in the knowledge of human evolution. Many scientific methods are involved in this investigation including chemical analysis of pigments present on artefacts or applied to cave walls. In the past decades, the characterization of coloured materials was carried on by taking ...
Graziani Rebecca R Università Commerciale Luigi Bocconi, Milan, - - 2014
The effect of a targeted agent on a cancer patient's clinical outcome putatively is mediated through the agent's effect on one or more early biological events. This is motivated by pre-clinical experiments with cells or animals that identify such events, represented by binary or quantitative biomarkers. When evaluating targeted agents ...
Vlasblom James J Department of Biochemistry, University of Regina, 3737 Wascana Parkway, Regina, SK S4S0A2, - - 2014
The model bacterium Escherichia coli is among the best studied prokaryotes, yet nearly half of its proteins are still of unknown biological function. This is despite a wealth of available large-scale physical and genetic interaction data. To address this, we extended the GeneMANIA function prediction web application developed for model ...
Walsh Jesse R - - 2014
BackgroundBioCyc databases are an important resource for information on biological pathways and genomic data. Such databases represent the accumulation of biological data, some of which has been manually curated from literature. An essential feature of these databases is the continuing data integration as new knowledge is discovered. As functional annotations ...
Meng Xuan-Yu XY Institute of Quantitative Biology and Medicine, Jiangsu Provincial Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou 215123, China. - - 2014
Growing experimental evidences suggest that dimerization and oligomerization are important for G Protein-Coupled Receptors (GPCRs) function. The detailed structural information of dimeric/oligomeric GPCRs would be very important to understand their function. Although it is encouraging that recently several experimental GPCR structures in oligomeric forms have appeared, experimental determination of GPCR ...
Brun-Usan M M Genomics, Bioinformatics and Evolution, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Barcelona, - - 2014
What proportion of the traits of individuals has been optimally shaped by natural selection and what has not? Here, we estimate the maximal number of those traits using a mathematical model for natural selection in multitrait organisms. The model represents the most ideal conditions for natural selection: a simple genotype-phenotype ...
Arbour J H JH Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON, - - 2014
Morphological, lineage and ecological diversity can vary substantially even among closely related lineages. Factors that influence morphological diversification, especially in functionally relevant traits, can help to explain the modern distribution of disparity across phylogenies and communities. Multivariate axes of feeding functional morphology from 75 species of Neotropical cichlid and a ...
Li Zitong Z University of - - 2014
Quantitative trait loci (QTL) mapping of wood properties in conifer species has focused on single time point measurements or on trait means based on heterogeneous wood samples (e.g. increment cores) thus ignoring systematic within-tree trends. In this study, functional QTL mapping was performed for a set of important wood properties ...
Saha Chiranjib - - 2014
This paper proposes a novel fuzzy rule-based penalty function approach for solving single-objective nonlinearly constrained optimization problems. Of all the existing state-of-the-art constraint handling techniques, the conventional method of penalty can be easily implemented because of its simplicity but suffers from the lack of robustness. To mitigate the problem of ...
Roshan A A MRC Cancer Cell Unit, Hutchison-MRC Research Centre, Cambridge CB2 2XZ, - - 2014
Biological tools such as genetic lineage tracing, three-dimensional confocal microscopy and next-generation DNA sequencing are providing new ways to quantify the distribution of clones of normal and mutated cells. Understanding population-wide clone size distributions in vivo is complicated by multiple cell types within observed tissues, and overlapping birth and death ...
Cervera Javier J Departament de Termodinàmica, Universitat de València, Burjassot 46100, Spain - - 2014
The interplay between cooperativity and diversity is crucial for biological ensembles because single molecule experiments show a significant degree of heterogeneity and also for artificial nanostructures because of the high individual variability characteristic of nanoscale units. We study the cross-effects between cooperativity and diversity in model threshold ensembles composed of ...
Read Mark M Department of Electronics, University of York, York YO10 5GW, UK - - 2014
We present a framework to assist the diagrammatic modelling of complex biological systems using the unified modelling language (UML). The framework comprises three levels of modelling, ranging in scope from the dynamics of individual model entities to system-level emergent properties. By way of an immunological case study of the mouse ...
Matoz-Fernandez D A DA Departamento de Física, Instituto de Física Aplicada, Universidad Nacional de San Luis-CONICET, Ejército de los Andes 950, D5700BWS San Luis, Argentina. - - 2014
The statistical thermodynamics of polyatomic species mixtures adsorbed on two-dimensional lattices was developed based on generalization of the semiempirical approximation for the adsorption of single components [Romá, F. et al., Langmuir, 2006, 22, 3192-3197]. In this scheme, the partial adsorption isotherms are obtained using a correction function C[combining tilde], which ...
Nouri-Mahdavi Kouros K The Jules Stein Eye Institute, David Geffen School of Medicine at UCLA, Los Angeles, California, - - 2014
Glaucoma is a progressive optic neuropathy. Hence, most glaucomatous eyes demonstrate signs of deterioration over time despite what may appear to be adequate treatment. The main goal of glaucoma treatment is to slow the rate of disease so that patients can prolong their functional vision. Therefore, it is important for ...
Proud Elizabeth E Department of Physiotherapy, School of Health Sciences, The University of Melbourne, 3010, Victoria, Australia. Electronic address: - - 2014
To identify measurement tools used for upper limb evaluation in people with Parkinson's disease (PD), to summarize the content of each tool using the International Classification of Functioning, Disability and Health (ICF), and examine the reliability, validity, clinical utility and responsiveness of the measurement tools specific to this clinical group. ...
van Gils Jan A JA Department of Marine Ecology, NIOZ Royal Netherlands Institute for Sea Research, P.O. Box 59, 1790 AB, Den Burg (Texel), The - - 2014
1.Models relating intake rate to food abundance and competitor densities (generalized functional response models) can predict forager distributions and movements between patches, but we lack understanding of how distributions and small-scale movements by the foragers themselves affect intake rates. 2.Using a state-of-the-art approach based on continuous-time Markov chain dynamics, we ...
Hu Jialu J Department of Mathematics and Computer Science, Freie Universität Berlin, Takustrasse 9, 14195 Berlin, Germany. - - 2014
Sequences and protein interaction data are of significance to understand the underlying molecular mechanism of organisms. Local network alignment is one of key systematic ways for predicting protein functions, identifying functional modules, and understanding the phylogeny from these data. Most of currently existing tools, however, encounter their limitations which are ...
Amsuess Sebastian - - 2014
Functional replacement of upper limbs by means of dexterous prosthetic devices remains a technological challenge. While the mechanical design of prosthetic hands have advanced rapidly, the human-machine interfacing and the control strategies needed for the activation of multiple degrees of freedom are not reliable enough for restoring hand function successfully. ...
Velazquez Miguel A MA a Centre for Biological Sciences , University of Southampton, Southampton General Hospital , Southampton , United - - 2014
Ovarian transvaginal ultrasonography (OTU) has been used world-wide for commercial ovum pick-up programs for in vitro embryo production in elite herds, providing an excellent model for the elucidation of factors controlling bovine oocyte developmental competence. Noninvasive sampling and treatment of ovarian structures is easily accomplished with bovine OTU techniques providing ...
Cirovic Ivana M IM Business Technical College of Vocational Studies, Uzice, - - 2014
Carl Bovill suggested and described a method of generating rhythm in architecture with the help of fractional Brownian functions, as they are mathematical models of natural rhythm. A relationship established in the stated procedure between fractional Brownian functions as models of rhythm, and the observed group of architectural elements, is ...
Spada Elena E Department of Clinical Sciences and Community Health, Unit of Medical Statistics and Biometry, Università degli Studi di Milano, Milan, I-20133, - - 2014
The Extended Mechanistic Growth Function (EMGF) method (Clementi et al. [1999]: Am J Med Genet 87:317-323) is a possible alternative to the Cole and Green LMS method ([1992] Stat Med 11:1305-1319) to construct cross-sectional anthropometric charts. It differs from the technique used by Kuczmarski et al. ([2002]: Vital Health Stat ...
Kamiya Ritsu R 1 Department of Life Science, Faculty of Science, Gakushuin University, 1-5-1 Mejiro, Toshima-ku, Tokyo 171-8588, - - 2014
This review outlines the current knowledge of the functional diversity of axonemal dyneins, as revealed by studies with the model organism Chlamydomonas. Axonemal dyneins, which comprise outer and inner dynein arms, power cilia and flagella beating by producing sliding movements between adjacent outer-doublet microtubules. Outer- and inner-arm dyneins have traditionally ...
Choi Jaedeug - - 2014
Inverse reinforcement learning (IRL) is the problem of inferring the underlying reward function from the expert's behavior data. The difficulty in IRL mainly arises in choosing the best reward function since there are typically an infinite number of reward functions that yield the given behavior data as optimal. Another difficulty ...
You Di - - 2014
Regression plays a major role in many scientific and engineering problems. The goal of regression is to learn the unknown underlying function from a set of sample vectors with known outcomes. In recent years, kernel methods in regression have facilitated the estimation of nonlinear functions. However, two major (interconnected) problems ...
Szymanski Lech - - 2014
We present a comparative theoretical analysis of representation in artificial neural networks with two extreme architectures, a shallow wide network and a deep narrow network, devised to maximally decouple their representative power due to layer width and network depth. We show that, given a specific activation function, models with comparable ...
Wang Yong Y School of Marine Science and Technology, Northwestern Polytechnical University, Xi'an, 710072, - - 2014
This paper presents a detailed study of the high-order superdirectivity of circular sensor arrays, which is aimed at completing the authors' recently proposed analytical superdirectivity model. From the limit expression of the maximum directivity factor, it is shown that the circular arrays possess good potential for directivity improvement. It is ...
Ji Jun Zhong - - 2014
Studies of functional modules in a Protein-Protein Interaction (PPI) network contribute greatly to theunderstanding of biological mechanisms. With the development of computing science,computational approaches have played an important role in detecting functional modules. We present a new approach using multi-agent evolution for detection of functional modules in PPInetworks. The proposed ...
Paterson Rachel A RA Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast, United Kingdom; School of Biology, University of Leeds, Leeds, United - - 2014
Predatory functional responses play integral roles in predator-prey dynamics, and their assessment promises greater understanding and prediction of the predatory impacts of invasive species. Other inter-specific interactions, however, such as parasitism and higher-order predation, have the potential to modify predator-prey interactions and thus the predictive capability of the comparative functional ...
Rockwood Alan L AL Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, UT, 84108, USA, - - 2014
Distortions of peaks can occur when one uses the standard method of signal processing of data from the Orbitrap and other FT-based methods of mass spectrometry. These distortions arise because the standard method of signal processing is not a linear process. If one adds two or more functions, such as ...
Ronacher Bernhard B Department of Biology, Behavioral Physiology Group, Humboldt-Universität zu Berlin, 10099, Berlin, Germany, - - 2014
Grasshoppers and crickets independently evolved hearing organs and acoustic communication. They differ considerably in the organization of their auditory pathways, and the complexity of their songs, which are essential for mate attraction. Recent approaches aimed at describing the behavioral preference functions of females in both taxa by a simple modeling ...
Wei Qinglai - - 2014
In this paper, a new iterative adaptive dynamic programming (ADP) algorithm is developed to solve optimal control problems for infinite horizon discrete-time nonlinear systems with finite approximation errors. First, a new generalized value iteration algorithm of ADP is developed to make the iterative performance index function converge to the solution ...
Benadjaoud Mohamed Amine MA Center for Research in Epidemiology and Population Health (CESP) INSERM 1018 Radiation, Epidemiology Group, Villejuif, France; Université Paris sud, Le Kremlin-Bicêtre, France; Institut Gustave Roussy, Villejuif, France. Electronic address: - - 2014
To describe a novel method to explore radiation dose-volume effects. Functional data analysis is used to investigate the information contained in differential dose-volume histograms. The method is applied to the normal tissue complication probability modeling of rectal bleeding (RB) for patients irradiated in the prostatic bed by 3-dimensional conformal radiation ...
Winkler Thomas W TW Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany, Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland, Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne 1010, Switzerland, Swiss Institute of Bioinformatics, Lausanne, Switzerland, Statistical Bioinformatics, Institute for Functional Genomics, University of Regensburg, Regensburg, Germany, Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, 6020 Innsbruck, Austria thomas.winkler@ukr.de - - 2014
The R package EasyStrata facilitates the evaluation and visualisation of stratified genome-wide association meta-analyses (GWAMAs) results. It provides (i) statistical methods to test and account for between-strata difference as a means to tackle gene-strata (GxS) interaction effects and (ii) extended graphical features tailored for stratified GWAMA results. The software provides ...
Chen Weisheng - - 2014
This paper addresses the problem of globally stable direct adaptive backstepping neural network (NN) tracking control design for a class of uncertain strict-feedback systems under the assumption that the accuracy of the ultimate tracking error is given a priori. In contrast to the classical adaptive backstepping NN control schemes, this ...
Meyer Matthew J MJ Graduate Program in Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry , London, Ontario , Canada - - 2014
Abstract Purpose: This systematic review summarizes the utility of variables available at acute discharge after stroke for predicting functional independence at discharge from inpatient rehabilitation. Methods: A systematic review of four electronic databases (Medline, EMBASE, PsycINFO and CINAHL) was conducted to identify studies reporting multivariable models predicting post-rehabilitation Barthel Index ...
Adams Richard - - 2014
A study was conducted to investigate the criterion validity of measures of upper extremity (UE) motor function derived during practice of virtual activities of daily living (ADLs). Fourteen hemiparetic stroke patients employed a Virtual Occupational Therapy Assistant (VOTA), consisting of a high-fidelity virtual world and a Kinect™ sensor, in four ...
Ragkos A A 1Department of Agricultural Technology,Alexander Technological Educational Institute of Thessaloniki,Sindos,57400 - - 2014
Market failures are the main cause of poor acknowledgement of the true impact of functional sheep traits on the management and economic performance of farms, which results in their omission from the breeding goal or the estimation of non-representative economic weights in the breeding goal. Consequently, stated-preference non-market valuation techniques, ...
Ogutu Jack J Department of Industrial and Systems Engineering, Auburn University, Auburn, AL, - - 2014
Few studies have investigated mathematical characteristics of the discomfort-time relationship during prolonged static posture holding (SPH) on an individual basis. Consequently, the discomfort-time relationship is not clearly understood at individual trial level.OBJECTIVE: The objective of this study was to examine discomfort-time sequence data obtained from a large number of maximum-duration ...
Royston Patrick P MRC Clinical Trials Unit, University College London, London, WC2B 6NH, - - 2014
In a large simulation study reported in a companion paper, we investigated the significance levels of 21 methods for investigating interactions between binary treatment and a continuous covariate in a randomised controlled trial. Several of the methods were shown to have inflated type 1 errors. In the present paper, we ...
Rahmati S M A SM Department of Mechanical Engineering, Iran University of Science and Technology, Iran. Electronic address: - - 2014
Using proper technique in different sports is an inevitable factor. In this study, available techniques for snatch weightlifting are mathematically evaluated. The optimal motion trajectory is a technique used by weightlifters, which could be determined based on minimizing specific object functions. Object functions based on total kinetic energy, total torque ...
Zhou Zhongxing - - 2014
The modulation transfer function (MTF) of radiographic systems is frequently evaluated by the system's line spread function (LSF) using narrow slits. The conventional slit method requires LSF tail approximation, which is achieved by exponentially extrapolating the LSF tails beyond 1% of peak value. However, the estimated MTF at low frequencies ...
Přecechtělová Jana J Département de Chimie, Université de Montréal, C.P. 6128 Succursale A, Montréal, Québec H3C 3J7, - - 2014
A persistent challenge in density functional theory is the construction of a nonempirical correlation functional that is compatible with the exact exchange energy. To solve this problem, we develop a correlation factor approach in which an exchange hole model, yielding the exact exchange energy, is multiplied by a correlation factor ...
Farkhondeh Mohammad M Department of Chemical Engineering, University of Waterloo, 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada. - - 2014
A simple mesoscopic model is presented which accounts for the inhomogeneity of physical properties and bi-stable nature of phase-change insertion materials used in battery electrodes. The model does not include any geometric detail of the active material and discretizes the total active material domain into meso-scale units featuring basic thermodynamic ...
Li Meixia M State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, - - 2014
Long noncoding RNA (lncRNA) is an emerging category of transcript, and comprises the majority of the transcriptome of various complex organisms. The biological functions of only a handful of lncRNAs have been investigated in detail, showing involvement in a wide range of biological processes through different functional paradigms. However, most ...
Kheirabadi Khabat K Department of Animal Science, University of Tabriz, Tabriz, - - 2014
We compared the goodness of fit of three mathematical functions (including: Legendre polynomials, Lidauer-Mäntysaari function and Wilmink function) for describing the lactation curve of primiparous Iranian Holstein cows by using multiple-trait random regression models (MT-RRM). Lactational submodels provided the largest daily additive genetic (AG) and permanent environmental (PE) variance estimates ...
Stahl Ulrike U Functional Biogeography Research Group, Max Planck Institute for Biogeochemistry, 07701 Jena, Germany; - - 2014
Using functional traits to explain species' range limits is a promising approach in functional biogeography. It replaces the idiosyncrasy of species-specific climate ranges with a generic trait-based predictive framework. In addition, it has the potential to shed light on specific filter mechanisms creating large-scale vegetation patterns. However, its application to ...
Whittaker Robert J RJ School of Geography and the Environment, University of Oxford, Oxford OX1 3QY, United Kingdom; Centre for Macroecology, Evolution and Climate, Department of Biology, University of Copenhagen, Copenhagen, Denmark; - - 2014
Analyses of species-diversity patterns of remote islands have been crucial to the development of biogeographic theory, yet little is known about corresponding patterns in functional traits on islands and how, for example, they may be affected by the introduction of exotic species. We collated trait data for spiders and beetles ...
Violle Cyrille C Centre d'Ecologie Fonctionelle et Evolutive, Unité Mixte de Recherche 5175, Centre National de la Recherche Scientifique, Université de Montpellier, Université Paul-Valéry Montpellier, École Pratique des Hautes Études, F-34293 Montpellier Cedex 5, France; Centre de Synthèse et d'Analyse sur la Biodiversité/Fondation pour la Recherche sur la Biodiversité, Domaine du Petit Arbois, Avenue Louis Philibert, 13545 Aix-en-Provence, France; - - 2014
Understanding, modeling, and predicting the impact of global change on ecosystem functioning across biogeographical gradients can benefit from enhanced capacity to represent biota as a continuous distribution of traits. However, this is a challenge for the field of biogeography historically grounded on the species concept. Here we focus on the ...
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