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Results 301 - 350 of 2462
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Alsaaod Maher - - 2014
Anaesthesia is mandatory for disbudding and castrating calves and lambs of any age, in Switzerland. According to the "anaesthesia delegation model" (ADM), anaesthesia for disbudding calves <3 weeks of age and castrating calves and lambs <2 weeks of age may be administered by certified farmers. Experience with this unique model ...
Prunières G J-C GJ Department of hand surgery, Strasbourg university hospital, 10, avenue Baumann, 67403 Illkirch, - - 2014
The aim of this study was to test the feasibility of a type of Japanese noodle, named "shirataki konnyaku", for microsurgery training in the operating room. Thirteen surgical residents without experience in microsurgery had to perform two microsurgical anastomoses: one on a model of a femoral artery of a rat ...
Sales J J Institute of Animal Science, Uhříněves, Prague, Czech - - 2014
Mathematical modelling of the relationships between mineral inputs and outputs would enable the prediction of mineral requirements of poultry under a wide range of conditions. To establish the feasibility of possible modelling of mineral requirements, the current study aimed to describe the individual mineral concentrations of whole bodies of quail ...
Rieppo Lassi L University of Eastern Finland, Department of Applied Physics, FI-70211 Kuopio, FinlandbKuopio University Hospital, Department of Clinical Neurophysiology, FI-70029 Kuopio, - - 2014
Articular cartilage (AC) is mainly composed of collagen, proteoglycans, chondrocytes, and water. These constituents are inhomogeneously distributed to provide unique biomechanical properties to the tissue. Characterization of the spatial distribution of these components in AC is important for understanding the function of the tissue and progress of osteoarthritis. Fourier transform ...
Lesaint Florian F Institut des Systèmes Intelligents et de Robotique, UMR 7222, UPMC Univ Paris 06, Paris, France ; Institut des Systèmes Intelligents et de Robotique, UMR 7222, CNRS, Paris, - - 2014
Reinforcement Learning has greatly influenced models of conditioning, providing powerful explanations of acquired behaviour and underlying physiological observations. However, in recent autoshaping experiments in rats, variation in the form of Pavlovian conditioned responses (CRs) and associated dopamine activity, have questioned the classical hypothesis that phasic dopamine activity corresponds to a ...
Dube B B Department of Animal Sciences, Stellenbosch University, Matielend, South - - 2014
Variance components for production traits were estimated using different models to evaluate maternal effects. Data analysed were records from the South African pig performance testing scheme on 22 224 pigs from 18 herds, tested between 1990 and 2008. The traits analysed were backfat thickness (BFAT), test period weight gain (TPG), lifetime ...
Pauluhn Jürgen J Toxicology, Bayer Pharma, 42096 Wuppertal, Germany. Electronic address: - - 2014
Convincing evidence suggests that high-surface-activity nano-materials, such as MWCNT, exert two modes of action (MoA), in which one appears to be related to surface activity/area and occurs concurrent with deposition, and the other is related to cumulative lung burden. Pulmonary inflammation induced by the latter mode appears to be dependent ...
Caccamo M M CoRFiLaC, Regione Siciliana, 97100 Ragusa, Italy. Electronic address: - - 2014
As part of a larger project aiming to develop management evaluation tools based on results from test-day (TD) models, the objective of this study was to examine the effect of physical composition of total mixed rations (TMR) tested quarterly from March 2006 through December 2008 on milk, fat, and protein ...
Lu Liangjian L Physiological Laboratory, Cambridge CB2 3EG, UK. - - 2014
The Na(+)-K(+)-2Cl(-) cotransporter NKCC2 is exclusively expressed in the renal thick ascending limb (TAL), where it exists as three main splice isoforms, NKCC2B, NKCC2A, and NKCC2F, with the latter two predominating. NKCC2A is expressed in both medullary and cortical TAL, but NKCC2F localizes to the medullary TAL. The biochemical characteristics ...
Kale Sohan S Department of Mechanical Science and Engineering, Institute for Condensed Matter Theory and Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, Illinois 61820, - - 2014
A spring lattice model with the ability to simulate elastic-plastic-brittle transitions in a disordered medium is presented. The model is based on bilinear constitutive law defined at the spring level and power-law-type disorder introduced in the yield and failure limits of the springs. The key parameters of the proposed model ...
Baker Tracie R TR Molecular and Environmental Toxicology Center, and Pharmaceutical Sciences, University of Wisconsin, Madison, WI - - 2014
2,3,7,8 Tetrachlorodibenzo-p-dioxin (TCDD) has been associated with many disease states in humans. A rising concern is that exposure early in life can lead to adult toxicity and toxicity in subsequent generations. Juvenile zebrafish exposed to TCDD (50 pg/ml in water; 1 h exposure) at 3 and 7 weeks post fertilization ...
Li Xingang X Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University Health Science Center , Beijing , People's Republic of China - - 2014
Abstract Modeling and simulation are aimed at achieving information about the behaviors of the drugs without the actual measurements and determination. The purpose of this study was to characterize the in vivo behavior of exenatide microspheres using model-based methods. Exenatide is a glucagon-like peptide-1 agonist medication, belonging to the group ...
Podgornik Aleš A BIA Separations d.o.o., Mirce 21, 5270 Ajdovščina, Slovenia; COBIK, Tovarniška 26, 5270 Ajdovščina, Slovenia. Electronic address: - - 2014
Chromatographic monoliths have several interesting properties making them attractive supports for analytics but also for purification, especially of large biomolecules and bioassemblies. Although many of monolith features were thoroughly investigated, there is no data available to predict how monolith mechanical properties affect its chromatographic performance. In this work, we investigated ...
Nielsen Hanne M - - 2014
The aim of the study was to estimate genetic parameters for direct and social genetic effects (SGE) for growth and welfare traits in farmed Atlantic cod (Gadus morhua). A SGE refers to the effect of an individual's genes on trait performance of its social partners. In total, 2100 individually tagged ...
Freutel Maren M Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research Ulm, University of Ulm, Ulm, Germany. Electronic address: - - 2014
Musculoskeletal soft tissues, such as articular cartilage, ligaments, knee meniscus and intervertebral disk, have a complex structure, which provides elasticity and capability to support and distribute the body loads. Soft tissues describe an inhomogeneous and multiphasic structure, and exhibit a nonlinear, time-dependent behavior. Their mechanical response is governed by a ...
Downs N J NJ Faculty of Health, Engineering and Sciences, University of Southern Queensland, Toowoomba 4350, Australia. Electronic address: - - 2014
Simultaneous personal measurements of the occupational ultraviolet exposure weighted to the International Commission on Non-Ionising Radiation Protection hazard sensitivity spectrum (UVICNIRP) were made over a five week period (44 person-days) in the second half of the summer school term of 2012 in Queensland, Australia for individual high school teachers located ...
Tiburtius Sara S AG Numerik und Wissenschaftliches Rechnen, TU Darmstadt, FB Mathematik, Dolivostr. 15, 64293 , Darmstadt, - - 2014
The key parameters influencing the elastic properties of the mineralized turkey leg tendon (MTLT) were investigated. Two structurally different tissue types appearing in the MTLT were considered: circumferential and interstitial tissue. These differ in their amount of micropores and their average diameter of the mineralized collagen fibril bundles. A multiscale ...
Liu Dong D The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, PR - - 2014
A physiologically based toxicokinetic and toxicodynamic (PBTK-TD) model was developed for benzo[a]pyrene (B[a]P) in scallop Chlamys farreri. The PBTK model structure consisted of gill, digestive gland, adductor muscle, hemolymph and other tissues. In TD modeling, aryl hydrocarbon hydroxylase (AHH) activity assay, comet assay, protein carbonyl measurement and lipid peroxidation level ...
Van de Poel Bram B Division of MeBioS, Department of Biosystems (BIOSYST), KU Leuven, Willem de Croylaan 42, bus 2428, 3001, Leuven, - - 2014
The gaseous plant hormone ethylene is involved in many physiological processes including climacteric fruit ripening, in which it is a key determinant of fruit quality. A detailed model that describes ethylene biochemistry dynamics is missing. Often, kinetic modeling is used to describe metabolic networks or signaling cascades, mostly ignoring the ...
Tilbury Karissa K Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, - - 2014
A profound remodeling of the extracellular matrix occurs in many epithelial cancers. In ovarian cancer, the minor collagen isoform of Col III becomes upregulated in invasive disease. Here we use second harmonic generation (SHG) imaging microscopy to probe structural differences in fibrillar models of the ovarian stroma comprised of mixtures ...
Campos G S GS Department of Animal Production, Federal University of Rio Grande do Sul, Porto Alegre, - - 2014
A bioeconomic model was developed to calculate economic values for biological traits in full-cycle production systems and propose selection indices based on selection criteria used in the Brazilian Aberdeen Angus genetic breeding programme (PROMEBO). To assess the impact of changes in the performance of the traits on the profit of ...
Russo Laura - - 2014
Despite the relevance of carbohydrates as cues in eliciting specific biological responses, the covalent surface modification of collagen-based matrices with small carbohydrate epitopes has been scarcely investigated. We report thereby the development of an efficient procedure for the chemoselective neoglycosylation of collagen matrices (patches) via a thiol-ene approach, between alkene-derived ...
Hall Adam J AJ Departments of Mathematics and Statistics, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK. Electronic address: - - 2014
A four compartment mechanistic mathematical model is developed for the pharmacokinetics of the commonly used anti-malarial drug artesunate and its principle metabolite dihydroartemisinin following oral administration of artesunate. The model is structurally unidentifiable unless additional constraints are imposed. Combinations of mechanistically derived constraints are considered to assess their effects on ...
Cavallo Jaime A JA Section of Minimally Invasive Surgery, Department of Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8109, St. Louis, MO, 63110, - - 2014
The purpose of this study was to evaluate the associations between patient characteristics or surgical site classifications and the histologic remodeling scores of synthetic meshes biopsied from their abdominal wall repair sites in the first attempt to generate a multivariable risk prediction model of non-constructive remodeling. Biopsies of the synthetic ...
Regier Michael D - - 2014
Abstract We performed an empirical study to evaluate the effect of mismeasured continuous confounders on the estimation of the causal parameter when using marginal structural models and inverse probability-of-treatment weighting. By executing an extensive simulation using 500 randomly generated parameter value combinations within a defined space, we observed the well-understood ...
Bouwman Aniek C - - 2014
Knowledge regarding causal relationships among traits is important to understand complex biological systems. Structural equation models (SEM) can be used to quantify the causal relations between traits, which allow prediction of outcomes to interventions applied to such a network. Such models are fitted conditionally on a causal structure among traits, ...
Duan Xiaojuan X a School of Mechanical and Chemical Engineering, The University of Western Australia , 35 Stirling Highway, Crawley WA 6009 Perth , - - 2014
A close relationship has been found between the 3D collagen structure and physiological condition of articular cartilage (AC). Studying the 3D collagen network in AC offers a way to determine the condition of the cartilage. However, traditional qualitative studies are time consuming and subjective. This study aims to develop a ...
Beuk Jonathan J Centre for Neuroscience Studies, Queen's University, Kingston, Ontario, Canada K7L - - 2014
The countermanding paradigm investigates the ability to withhold a response when a stop signal is presented occasionally. The race model (Logan and Cowan, 1984) was developed to account for performance in humans and to estimate the stop signal response time (SSRT). This model has yet to be fully validated for ...
Hassan S S 1Department for Plastic and Reconstructive Surgery, Ninewells Hospital and Medical School, Dundee, - - 2014
The aim of this study was to compare Thiel-embalmed cadavers with formalin-embalmed cadavers and porcine models in the surgical simulation repair of a Zone II flexor tendon division. Nine participants were recruited to the study. The models were assessed using a five-point scale. Assessment was divided into tissue quality, surgical ...
Goh K L KL School of Mechanical and Systems Engineering, Newcastle University, Newcastle upon Tyne, UK, - - 2014
Augmentation of the mechanical properties of connective tissue using ultraviolet (UV) radiation-by targeting collagen cross-linking in the tissue at predetermined UV exposure time [Formula: see text] and wavelength [Formula: see text]-has been proposed as a therapeutic method for supporting the treatment for structural-related injuries and pathologies. However, the effects of ...
Müllerová Ludmila L Charles University in Prague, Faculty of Science, Department of Physical and Macromolecular Chemistry, Prague, Czech - - 2014
We introduce an easy but highly descriptive model of separation efficiency of dual-selector systems in capillary electrophoresis. The model expresses effective mobilities of analytes in dual-selector mixtures as a function of mixture composition and total concentration. The effective mobility follows the pattern familiar from single-selector systems, while complexation constant and ...
Barros Ana M G AM Centro de Estudos Florestais, Instituto Superior de Agronomia, Universidade de Lisboa, Lisboa, - - 2014
Previous research has shown that fires burn certain land cover types disproportionally to their abundance. We used quantile regression to study land cover proneness to fire as a function of fire size, under the hypothesis that they are inversely related, for all land cover types. Using five years of fire ...
Chen Hua H Department of Orthopaedics Surgery, PLA General Hospital, Fuxinglu 28, Haidian District, Beijing, 100853, - - 2014
We created 66 male and 74 female virtual three-dimensional models of the pelvis based on computed tomography data from 140 patients. Virtual cylindrical bolts (VCBs) were placed in the anterior column (AC), which was then resliced serially along the bolt's long axis. AC screw tunnel mainly comprises two long, narrow ...
Papastamoulis Panagiotis - - 2014
Abstract RNA-seq studies allow for the quantification of transcript expression by aligning millions of short reads to a reference genome. However, transcripts share much of their sequence, so that many reads map to more than one place and their origin remains uncertain. This problem can be dealt using mixtures of ...
Tseng Chih-Yuan CY Department of Oncology, University of Alberta, Edmonton, Alberta, - - 2014
Toll-like receptor protein 7 (TLR7) is a transmembrane protein playing a crucial role in the signaling pathways involved in innate immunity. Its crystal structure is not yet available, but there are several proteins with possessing domain of sufficiently high homology, which enabled us to build a model of the TLR7 ...
Hamaji Masatsugu M Department of Bioartificial Organs, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan, - - 2014
Intrapleural and anti-adhesive materials were investigated in murine models, but not in a large animal model before clinical application. Our results failed to show any anti-adhesion effect of collagen fleece and suggested the thoracic physiology in murine models would not translate into a large animal model.
Bar Amir A Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 7610001, - - 2014
We introduce and analyze an exactly soluble one-dimensional Ising model with long range interactions that exhibits a mixed-order transition, namely a phase transition in which the order parameter is discontinuous as in first order transitions while the correlation length diverges as in second order transitions. Such transitions are known to ...
Dumestre Danielle D University of Calgary, Alberta, - - 2014
The purpose of this study is to (1) systematically review all the literature pertaining to microsurgical training models and to (2) determine which of these are specific to and validated for microsurgery training. PubMed, MEDLINE (OVID/EBSCO), Google Scholar, and Cochrane Central Register of Controlled Trials were searched using preset terms. ...
Canet Mark J MJ University of Arizona, Department of Pharmacology and - - 2014
Nonalcoholic fatty liver disease (NAFLD) is a prevalent form of chronic liver disease that can progress to the more advanced stage of nonalcoholic steatohepatitis (NASH). NASH has been shown to alter drug transporter regulation and may have implications in the development of adverse drug reactions. Several experimental rodent models have ...
Schroeter Jeffry D JD Applied Research Associates, Inc., Raleigh, NC - - 2014
Formaldehyde is a nasal carcinogen in rodents at high doses and is an endogenous compound that is present in all living cells. Due to its high solubility and reactivity, quantitative risk estimates for inhaled formaldehyde have relied on internal dose estimates in the upper respiratory tract. Dosimetry calculations are complicated ...
do Nascimento N F F NF Laboratório de Análises de Progênies, Departamento de Fitotecnia, Pós-Graduação em Genética e Melhoramento, Centro de Ciências Agrárias, Universidade Federal de Viçosa, Viçosa, Minas Gerais, - - 2014
The objective of this study was to determine the effects of the general and specific combining abilities (GCA and SCA, respectively) of 15 characteristics and to evaluate the most promising crosses and the reciprocal effect between the hybrids of six parents of the Capsicum annuum species. Six parents, belonging to ...
Grupe Gisela - - 2014
The application of mixing models for the sourcing of dietary end members, which mix into consumer collagen delta13C and delta15N isotopic ratios, has clear benefits for understanding human palaeodiet and human and vertebrate palaeoecology. This is because traditional visual or conventional statistical interpretations of bivariate plots may be erroneous or ...
Chen Zeqiang Z Institute of Space and Earth Information Science, The Chinese University of Hong Kong, Shatin, Hong Kong ; Collaborative Innovation Center for Geospatial Information Technology, Wuhan University, Wuhan 430079, China ; Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen 518057, - - 2014
Sharing and integrating Remote Sensing (RS) and Geographic Information System/Science (GIS) models are critical for developing practical application systems. Facilitating model sharing and model integration is a problem for model publishers and model users, respectively. To address this problem, a framework based on a Web service for sharing and integrating ...
Torii Manabu M Department of Radiology, Georgetown University Medical Center, Washington, DC, USA. - - 2014
Identifying phrases that refer to particular concept types is a critical step in extracting information from documents. Provided with annotated documents as training data, supervised machine learning can automate this process. When building a machine learning model for this task, the model may be built to detect all types simultaneously ...
Langmead Christopher James CJ Carnegie Mellon University, Pittsburgh, PA, USA, - - 2014
Atomistic simulations of the conformational dynamics of proteins can be performed using either Molecular Dynamics or Monte Carlo procedures. The ensembles of three-dimensional structures produced during simulation can be analyzed in a number of ways to elucidate the thermodynamic and kinetic properties of the system. The goal of this chapter ...
Nielsen J Rasmus JR Technical University of Denmark, National Institute of Aquatic Resources (DTU AQUA), Charlottenlund, - - 2014
Trawl survey data with high spatial and seasonal coverage were analysed using a variant of the Log Gaussian Cox Process (LGCP) statistical model to estimate unbiased relative fish densities. The model estimates correlations between observations according to time, space, and fish size and includes zero observations and over-dispersion. The model ...
Zhang Xiaohang X School of Economics and Management, Beijing University of Posts and Telecommunications, Beijing, - - 2014
A complex network is a useful tool for representing and analyzing complex systems, such as the world-wide web and transportation systems. However, the growing size of complex networks is becoming an obstacle to the understanding of the topological structure and their characteristics. In this study, a globally and locally adaptive ...
Di Marco Fabiana F Department of Biotechnology and Applied Clinical Science, University of L'Aquila, L'Aquila, - - 2014
The central nervous system undergoing degeneration can be stabilized, and in some models can be restored to function, by neuroprotective treatments. Photobiomodulation (PBM) and dietary saffron are distinctive as neuroprotectants in that they upregulate protective mechanisms, without causing measurable tissue damage. This study reports a first attempt to combine the ...
Liu Enqiang E University of Science and Technology Beijing, Beijing 100083, - - 2014
The contents access and sharing in multimedia social networks (MSNs) mainly rely on access control models and mechanisms. Simple adoptions of security policies in the traditional access control model cannot effectively establish a trust relationship among parties. This paper proposed a novel two-party trust architecture (TPTA) to apply in a ...
Aguilar Alex A Department of Animal Biology and Biodiversity Research Institute (IrBio), Faculty of Biology, University of Barcelona, Barcelona, - - 2014
The finding that tissue δ15N values increase with protein catabolism has led researchers to apply this value to gauge nutritive condition in vertebrates. However, its application to marine mammals has in most occasions failed. We investigated the relationship between δ15N values and the fattening/fasting cycle in a model species, the ...
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