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Results 301 - 350 of 2430
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Downs N J NJ Faculty of Health, Engineering and Sciences, University of Southern Queensland, Toowoomba 4350, Australia. Electronic address: - - 2014
Simultaneous personal measurements of the occupational ultraviolet exposure weighted to the International Commission on Non-Ionising Radiation Protection hazard sensitivity spectrum (UVICNIRP) were made over a five week period (44 person-days) in the second half of the summer school term of 2012 in Queensland, Australia for individual high school teachers located ...
Freutel Maren M Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal Research Ulm, University of Ulm, Ulm, Germany. Electronic address: - - 2014
Musculoskeletal soft tissues, such as articular cartilage, ligaments, knee meniscus and intervertebral disk, have a complex structure, which provides elasticity and capability to support and distribute the body loads. Soft tissues describe an inhomogeneous and multiphasic structure, and exhibit a nonlinear, time-dependent behavior. Their mechanical response is governed by a ...
Tiburtius Sara S AG Numerik und Wissenschaftliches Rechnen, TU Darmstadt, FB Mathematik, Dolivostr. 15, 64293 , Darmstadt, - - 2014
The key parameters influencing the elastic properties of the mineralized turkey leg tendon (MTLT) were investigated. Two structurally different tissue types appearing in the MTLT were considered: circumferential and interstitial tissue. These differ in their amount of micropores and their average diameter of the mineralized collagen fibril bundles. A multiscale ...
Liu Dong D The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, PR - - 2014
A physiologically based toxicokinetic and toxicodynamic (PBTK-TD) model was developed for benzo[a]pyrene (B[a]P) in scallop Chlamys farreri. The PBTK model structure consisted of gill, digestive gland, adductor muscle, hemolymph and other tissues. In TD modeling, aryl hydrocarbon hydroxylase (AHH) activity assay, comet assay, protein carbonyl measurement and lipid peroxidation level ...
Van de Poel Bram B Division of MeBioS, Department of Biosystems (BIOSYST), KU Leuven, Willem de Croylaan 42, bus 2428, 3001, Leuven, - - 2014
The gaseous plant hormone ethylene is involved in many physiological processes including climacteric fruit ripening, in which it is a key determinant of fruit quality. A detailed model that describes ethylene biochemistry dynamics is missing. Often, kinetic modeling is used to describe metabolic networks or signaling cascades, mostly ignoring the ...
Tilbury Karissa K Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, - - 2014
A profound remodeling of the extracellular matrix occurs in many epithelial cancers. In ovarian cancer, the minor collagen isoform of Col III becomes upregulated in invasive disease. Here we use second harmonic generation (SHG) imaging microscopy to probe structural differences in fibrillar models of the ovarian stroma comprised of mixtures ...
Campos G S GS Department of Animal Production, Federal University of Rio Grande do Sul, Porto Alegre, - - 2014
A bioeconomic model was developed to calculate economic values for biological traits in full-cycle production systems and propose selection indices based on selection criteria used in the Brazilian Aberdeen Angus genetic breeding programme (PROMEBO). To assess the impact of changes in the performance of the traits on the profit of ...
Russo Laura - - 2014
Despite the relevance of carbohydrates as cues in eliciting specific biological responses, the covalent surface modification of collagen-based matrices with small carbohydrate epitopes has been scarcely investigated. We report thereby the development of an efficient procedure for the chemoselective neoglycosylation of collagen matrices (patches) via a thiol-ene approach, between alkene-derived ...
Hall Adam J AJ Departments of Mathematics and Statistics, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK. Electronic address: - - 2014
A four compartment mechanistic mathematical model is developed for the pharmacokinetics of the commonly used anti-malarial drug artesunate and its principle metabolite dihydroartemisinin following oral administration of artesunate. The model is structurally unidentifiable unless additional constraints are imposed. Combinations of mechanistically derived constraints are considered to assess their effects on ...
Cavallo Jaime A JA Section of Minimally Invasive Surgery, Department of Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8109, St. Louis, MO, 63110, - - 2014
The purpose of this study was to evaluate the associations between patient characteristics or surgical site classifications and the histologic remodeling scores of synthetic meshes biopsied from their abdominal wall repair sites in the first attempt to generate a multivariable risk prediction model of non-constructive remodeling. Biopsies of the synthetic ...
Regier Michael D - - 2014
Abstract We performed an empirical study to evaluate the effect of mismeasured continuous confounders on the estimation of the causal parameter when using marginal structural models and inverse probability-of-treatment weighting. By executing an extensive simulation using 500 randomly generated parameter value combinations within a defined space, we observed the well-understood ...
Bouwman Aniek C - - 2014
Knowledge regarding causal relationships among traits is important to understand complex biological systems. Structural equation models (SEM) can be used to quantify the causal relations between traits, which allow prediction of outcomes to interventions applied to such a network. Such models are fitted conditionally on a causal structure among traits, ...
Duan Xiaojuan X a School of Mechanical and Chemical Engineering, The University of Western Australia , 35 Stirling Highway, Crawley WA 6009 Perth , - - 2014
A close relationship has been found between the 3D collagen structure and physiological condition of articular cartilage (AC). Studying the 3D collagen network in AC offers a way to determine the condition of the cartilage. However, traditional qualitative studies are time consuming and subjective. This study aims to develop a ...
Stenberg Pauline P Department of Forest Sciences, PO Box 27, FI-00014 University of Helsinki, - - 2014
Background and AimsProper characterization of the clumped structure of forests is needed for calculation of the absorbed radiation and photosynthetic production by a canopy. This study examined the dependency of crown-level clumping on tree size and growth conditions in Scots pine (Pinus sylvestris), and determined the ability of statistical canopy ...
Hassan S S 1Department for Plastic and Reconstructive Surgery, Ninewells Hospital and Medical School, Dundee, - - 2014
The aim of this study was to compare Thiel-embalmed cadavers with formalin-embalmed cadavers and porcine models in the surgical simulation repair of a Zone II flexor tendon division. Nine participants were recruited to the study. The models were assessed using a five-point scale. Assessment was divided into tissue quality, surgical ...
Beuk Jonathan J Centre for Neuroscience Studies, Queen's University, Kingston, Ontario, Canada K7L - - 2014
The countermanding paradigm investigates the ability to withhold a response when a stop signal is presented occasionally. The race model (Logan and Cowan, 1984) was developed to account for performance in humans and to estimate the stop signal response time (SSRT). This model has yet to be fully validated for ...
Goh K L KL School of Mechanical and Systems Engineering, Newcastle University, Newcastle upon Tyne, UK, - - 2014
Augmentation of the mechanical properties of connective tissue using ultraviolet (UV) radiation-by targeting collagen cross-linking in the tissue at predetermined UV exposure time [Formula: see text] and wavelength [Formula: see text]-has been proposed as a therapeutic method for supporting the treatment for structural-related injuries and pathologies. However, the effects of ...
Barros Ana M G AM Centro de Estudos Florestais, Instituto Superior de Agronomia, Universidade de Lisboa, Lisboa, - - 2014
Previous research has shown that fires burn certain land cover types disproportionally to their abundance. We used quantile regression to study land cover proneness to fire as a function of fire size, under the hypothesis that they are inversely related, for all land cover types. Using five years of fire ...
Müllerová Ludmila L Charles University in Prague, Faculty of Science, Department of Physical and Macromolecular Chemistry, Prague, Czech - - 2014
We introduce an easy but highly descriptive model of separation efficiency of dual-selector systems in capillary electrophoresis. The model expresses effective mobilities of analytes in dual-selector mixtures as a function of mixture composition and total concentration. The effective mobility follows the pattern familiar from single-selector systems, while complexation constant and ...
Chen Hua H Department of Orthopaedics Surgery, PLA General Hospital, Fuxinglu 28, Haidian District, Beijing, 100853, - - 2014
We created 66 male and 74 female virtual three-dimensional models of the pelvis based on computed tomography data from 140 patients. Virtual cylindrical bolts (VCBs) were placed in the anterior column (AC), which was then resliced serially along the bolt's long axis. AC screw tunnel mainly comprises two long, narrow ...
Papastamoulis Panagiotis - - 2014
Abstract RNA-seq studies allow for the quantification of transcript expression by aligning millions of short reads to a reference genome. However, transcripts share much of their sequence, so that many reads map to more than one place and their origin remains uncertain. This problem can be dealt using mixtures of ...
Tseng Chih-Yuan CY Department of Oncology, University of Alberta, Edmonton, Alberta, - - 2014
Toll-like receptor protein 7 (TLR7) is a transmembrane protein playing a crucial role in the signaling pathways involved in innate immunity. Its crystal structure is not yet available, but there are several proteins with possessing domain of sufficiently high homology, which enabled us to build a model of the TLR7 ...
Hamaji Masatsugu M Department of Bioartificial Organs, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan, - - 2014
Intrapleural and anti-adhesive materials were investigated in murine models, but not in a large animal model before clinical application. Our results failed to show any anti-adhesion effect of collagen fleece and suggested the thoracic physiology in murine models would not translate into a large animal model.
Bar Amir A Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 7610001, - - 2014
We introduce and analyze an exactly soluble one-dimensional Ising model with long range interactions that exhibits a mixed-order transition, namely a phase transition in which the order parameter is discontinuous as in first order transitions while the correlation length diverges as in second order transitions. Such transitions are known to ...
Dumestre Danielle D University of Calgary, Alberta, - - 2014
The purpose of this study is to (1) systematically review all the literature pertaining to microsurgical training models and to (2) determine which of these are specific to and validated for microsurgery training. PubMed, MEDLINE (OVID/EBSCO), Google Scholar, and Cochrane Central Register of Controlled Trials were searched using preset terms. ...
Canet Mark J MJ University of Arizona, Department of Pharmacology and - - 2014
Nonalcoholic fatty liver disease (NAFLD) is a prevalent form of chronic liver disease that can progress to the more advanced stage of nonalcoholic steatohepatitis (NASH). NASH has been shown to alter drug transporter regulation and may have implications in the development of adverse drug reactions. Several experimental rodent models have ...
Schroeter Jeffry D JD Applied Research Associates, Inc., Raleigh, NC - - 2014
Formaldehyde is a nasal carcinogen in rodents at high doses and is an endogenous compound that is present in all living cells. Due to its high solubility and reactivity, quantitative risk estimates for inhaled formaldehyde have relied on internal dose estimates in the upper respiratory tract. Dosimetry calculations are complicated ...
Mason Christopher E - - 2014
In today's biology, studies have shifted to analyzing systems over discrete biochemical reactions and pathways. These studies depend on combining the results from scores of experimental methods that analyze DNA; mRNA; noncoding RNAs, DNA, RNA, and protein interactions; and the nucleotide modifications that form the epigenome into global datasets that ...
Pawelec K M KM Department of Materials Science and Metallurgy, University of Cambridge, , 27 Charles Babbage Road, Cambridge CB3 0FS, - - 2014
In this paper, we show, for the first time, the key link between scaffold architecture and latent heat evolution during the production of porous biomedical collagen structures using freeze-drying. Collagen scaffolds are used widely in the biomedical industry for the repair and reconstruction of skeletal tissues and organs. Freeze-drying of ...
Feng Mei-Chen MC Institute of Dryland Farming Engineer, Shanxi Agricultural University, Taigu, People's Republic of - - 2014
In this study, relationships between normalized difference vegetation index (NDVI) and plant (winter wheat) nitrogen content (PNC) and between PNC and grain protein content (GPC) were investigated using multi-temporal moderate-resolution imaging spectroradiometer (MODIS) data at the different stages of winter wheat in Linfen (Shanxi, P. R. China). The anticipating model ...
Delellis Pietro P 1] Department of Electrical Engineering and Information Technology, University of Naples Federico II, Naples 80125, Italy [2] Department of Mechanical and Aerospace Engineering, Polytechnic School of Engineering, New York University, Brooklyn, New York 11201, - - 2014
We posit a new geometric perspective to define, detect, and classify inherent patterns of collective behaviour across a variety of animal species. We show that machine learning techniques, and specifically the isometric mapping algorithm, allow the identification and interpretation of different types of collective behaviour in five social animal species. ...
Meyer Carl G CG Hawaii Institute of Marine Biology, University of Hawaii at Manoa, Honolulu, Hawai'i, United States of - - 2014
Tiger sharks (Galecerdo cuvier) are apex predators characterized by their broad diet, large size and rapid growth. Tiger shark maximum size is typically between 380 & 450 cm Total Length (TL), with a few individuals reaching 550 cm TL, but the maximum size of tiger sharks in Hawaii waters remains ...
Krivitsky Pavel N PN Pennsylvania State University, University Park, - - 2014
Models of dynamic networks - networks that evolve over time - have manifold applications. We develop a discrete-time generative model for social network evolution that inherits the richness and flexibility of the class of exponential-family random graph models. The model - a Separable Temporal ERGM (STERGM) - facilitates separable modeling ...
Rupp Matthias M Department of Chemistry and Applied Biosciences, Eidgenössische Technische Hochschule (ETH), Zürich, - - 2014
Machine learning has been used for estimation of potential energy surfaces to speed up molecular dynamics simulations of small systems. We demonstrate that this approach is feasible for significantly larger, structurally complex molecules, taking the natural product Archazolid A, a potent inhibitor of vacuolar-type ATPase, from the myxobacterium Archangium gephyra ...
Borondo J J 1] Macro Connections, The MIT Media Lab, Massachusetts Institute of Technology, Cambridge, MA [2] Grupo de Sistemas Complejos and Departamento de Física y Mecánica, Universidad Politécnica de Madrid, ETSI Agrónomos, 28040 Madrid, - - 2014
A system is said to be meritocratic if the compensation and power available to individuals is determined by their abilities and merits. A system is topocratic if the compensation and power available to an individual is determined primarily by her position in a network. Here we introduce a model that ...
Ares Manuel M - - 2014
Quality control must be maintained at every step of a microarray experiment, from RNA isolation through statistical evaluation. Here we provide suggestions for analyzing microarray data. Because the utility of the results depends directly on the design of the experiment, the first critical step is to ensure that the experiment ...
Torii Manabu M Department of Radiology, Georgetown University Medical Center, Washington, DC, USA. - - 2014
Identifying phrases that refer to particular concept types is a critical step in extracting information from documents. Provided with annotated documents as training data, supervised machine learning can automate this process. When building a machine learning model for this task, the model may be built to detect all types simultaneously ...
Jafree Hafsa Athar HA Department of Mathematical Sciences, University of Karachi, Karachi, - - 2014
This paper presents new simple approaches for evaluating determinant and inverse of a matrix. The choice of pivot selection has been kept arbitrary thus they reduce the error while solving an ill conditioned system. Computation of determinant of a matrix has been made more efficient by saving unnecessary data storage ...
Fang Keyan K Key Laboratory of Humid Subtropical Eco-Geographical Process (Ministry of Education), College of Geographical Sciences, Fujian Normal University, Fuzhou, Fujian Province, China ; Key Laboratory of Western China's Environmental Systems (Ministry of Education), Research School of Arid Environment and Climate Change, Lanzhou University, Lanzhou, Gansu Province, China ; Department of Geosciences and Geography, University of Helsinki, Helsinki City, Helsinki, - - 2014
Traditional detrending methods assign equal mean value to all tree-ring series for chronology developments, despite that the mean annual growth changes in different time periods. We find that the strength of a tree-ring model can be improved by giving more weights to tree-ring series that have a stronger climate signal ...
Tétard-Jones Catherine C Molecular Agriculture Group, Nafferton Ecological Farming Group, School of Agriculture, Food and Rural Development, Newcastle University, Newcastle-Upon-Tyne, United - - 2014
'Omics analysis (transcriptomics, proteomics) quantifies changes in gene/protein expression, providing a snapshot of changes in biochemical pathways over time. Although tools such as modelling that are needed to investigate the relationships between genes/proteins already exist, they are rarely utilised. We consider the potential for using Structural Equation Modelling to investigate ...
Sun Catherine C CC New York Cooperative Fish and Wildlife Research Unit, Department of Natural Resources, Cornell University, Ithaca New York, United States of - - 2014
An increasing number of studies employ spatial capture-recapture models to estimate population size, but there has been limited research on how different spatial sampling designs and trap configurations influence parameter estimators. Spatial capture-recapture models provide an advantage over non-spatial models by explicitly accounting for heterogeneous detection probabilities among individuals that ...
Buyel Johannes Felix JF Institute for Molecular Biotechnology, RWTH Aachen - - 2014
Plants provide multiple benefits for the production of biopharmaceuticals including low costs, scalability, and safety. Transient expression offers the additional advantage of short development and production times, but expression levels can vary significantly between batches thus giving rise to regulatory concerns in the context of good manufacturing practice. We used ...
Bhargava Kiran K Department of Pharmacology and Therapeutics, King George's Medical University Erstwhile CSMMU, Lucknow 226003, - - 2014
In this work, 3D model of D2 dopamine receptor was determined by comparative homology modeling program MODELLER. The computed model's energy was minimized and validated using PROCHECK and Errat tool to obtain a stable model structure and was submitted in Protein Model Database (PMDB-ID: PM0079251). Stable model was used for ...
Alaoui Moulay Abdelaziz El MA Functional Genomic Platform, UATRS, Center for Scientific and Technical Research [CNRST], Rabat, Morocco ; Laboratory of Genetics and Biometry, Faculty of Sciences, University Ibn - - 2014
The Δ(9-)Tetrahydrocannabinol (THCA) is the primary psychoactive compound of Cannabis Sativa. It is produced by Δ(1-) Tetrahydrocannabinolic acid synthase (THCA) which catalyzes the oxidative cyclization of cannabigerolic acid (CBGA) the precursor of the THCA. In this study, we were interested by the three dimensional structure of THCA synthase protein. Generation ...
Zhang H M HM Maize Research Institute, Shanxi Academy of Agricultural Sciences, Xinzhou City, - - 2014
Maize (Zea mays L.) is one of the most important crops in the world. In this study, 13 agronomic traits of a recombinant inbred line population that was derived from the cross between Mo17 and Huangzao4 were investigated in maize: ear diameter, ear length, ear axis diameter, ear weight, plant ...
Hübner Ronald R Fachbereich Psychologie, Universität Konstanz Konstanz, - - 2014
SOME RESULTS SUGGEST THAT ATTENTIONAL SELECTION IN GLOBAL/LOCAL PROCESSING OCCURS AT TWO STAGES: an early stage, where global and local information of a hierarchical stimulus is filtered or weighted according to the current goal, and a late stage, where the contents of the stimulus are bound to their respective level. ...
Dalbey Walden E WE DalbeyTox, LLC, 860 Penns Way, West Chester, PA, 19382, USA. Email: - - 2014
Lubricating oil base stocks (LOBs) are substances used in the manufacture of finished lubricants and greases. They are produced from residue remaining after atmospheric distillation of crude oil that is subsequently fractionated by vacuum distillation and additional refining steps. Initial LOB streams that have been produced by vacuum distillation but ...
Li Quanfeng - - 2014
The nutrient composition of corn is variable. To prevent unforeseen reductions in growth performance, grading and analytical methods are used to minimize nutrient variability between calculated and analyzed values. This experiment was carried out to define the sources of variation in the energy content of corn and to develop a ...
Oh S R SR Department of Food Science and Technology, Chung-Ang University, 72-1 Nae-ri, Daeduk-myun, Ansung, Gyunggido 456-756, Republic of - - 2014
The inhibitory effect of chlorine (50, 100, and 200 mg/kg) was investigated with and without UV radiation (300 mW·s/cm(2)) for the growth of Listeria monocytogenes in chicken breast meat. Using a polynomial model, predictive growth models were also developed as a function of chlorine concentration, UV exposure, and storage temperature ...
Yu Eunjong E 0000-0002-4098-5153 Department of Architectural Engineering, Hanyang University 222, Wangsimni-ro, Seongdong-gu, Seoul 133-791, Republic of - - 2014
Damage of a 5-story framed structure was identified from two types of measured data, which are frequency response functions (FRF) and natural frequencies, using a finite element (FE) model updating procedure. In this study, a procedure to determine the appropriate weightings for different groups of observations was proposed. In addition, ...
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